Dylan Gee, PhD
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Featured Publications
Neural circuitry involved in conditioned inhibition via safety signal learning is sensitive to trauma exposure
Kribakaran S, Odriozola P, Cohodes E, McCauley S, Zacharek S, Hodges H, Haberman J, Pierre J, Gee D. Neural circuitry involved in conditioned inhibition via safety signal learning is sensitive to trauma exposure. Neurobiology Of Stress 2022, 21: 100497. PMID: 36532365, PMCID: PMC9755062, DOI: 10.1016/j.ynstr.2022.100497.Peer-Reviewed Original ResearchLeveraging the science of stress to promote resilience and optimize mental health interventions during adolescence
Gee DG, Sisk LM, Cohodes EM, Bryce NV. Leveraging the science of stress to promote resilience and optimize mental health interventions during adolescence. Nature Communications 2022, 13: 5693. PMID: 36171218, PMCID: PMC9519553, DOI: 10.1038/s41467-022-33416-4.Peer-Reviewed Original ResearchNeural effects of controllability as a key dimension of stress exposure
Cohodes EM, Odriozola P, Mandell JD, Caballero C, McCauley S, Zacharek SJ, Hodges HR, Haberman JT, Smith M, Thomas J, Meisner OC, Ellis CT, Hartley CA, Gee DG. Neural effects of controllability as a key dimension of stress exposure. Development And Psychopathology 2022, 35: 218-227. PMID: 35034670, DOI: 10.1017/s0954579421001498.Peer-Reviewed Original ResearchConceptsDorsal anterior insulaRight dorsal anterior insulaUncontrollable stress conditionUncontrollable stressStress exposureSex-matched participantsStressor controllabilityInitial exposureFunctional magnetic resonance imaging (fMRI) acquisitionSubsequent stress exposureNeural effectsAnterior insulaYoung adultsSubsequent stressorsPatterns of activityCross-species evidenceNeural correlatesSubsequent exposureExposureNeural underpinningsPresent studyParticipantsMagnetic resonance imaging (MRI) acquisitionAdaptive responseFMRI analysisEarly Adversity and Development: Parsing Heterogeneity and Identifying Pathways of Risk and Resilience
Gee DG. Early Adversity and Development: Parsing Heterogeneity and Identifying Pathways of Risk and Resilience. American Journal Of Psychiatry 2021, 178: 998-1013. PMID: 34734741, DOI: 10.1176/appi.ajp.2021.21090944.Peer-Reviewed Original ResearchConceptsEarly adversityProtective factorsEffects of adversityOnset of psychopathologyPathways of riskNeurodevelopmental trajectoriesMajor risk factorAdversityMental healthNeurodevelopmental pathwaysEarly environmentPsychopathologySpecific dimensionsIntervention strategiesFuture researchRisk factorsEarly risk identificationTreatment approachesImmense burdenConceptual modelDevelopmental timingResilienceOngoing refinementRiskFactorsAssociations among negative life events, changes in cortico-limbic connectivity, and psychopathology in the ABCD Study
Brieant AE, Sisk LM, Gee DG. Associations among negative life events, changes in cortico-limbic connectivity, and psychopathology in the ABCD Study. Developmental Cognitive Neuroscience 2021, 52: 101022. PMID: 34710799, PMCID: PMC8556598, DOI: 10.1016/j.dcn.2021.101022.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityNegative life eventsLife eventsInternalizing symptomsAdversity exposureCortico-limbic connectivityParental acceptanceAdolescent Brain Cognitive Development (ABCD) studyLongitudinal structural equation modelLower internalizing symptomsCognitive Development StudyContext of adversityIndirect effectsSample of youthStressful childhood experiencesCortico-limbic networkStructural equation modelLater psychopathologyNeurobiological maturationInternalizing problemsABCD studyFunctional connectivityChildhood experiencesPotential protective effectPsychopathology
2025
The Endocannabinoid System and Postnatal Neurodevelopment
Sisk L, Meyer H, Martinez-Garcia A, Gee D. The Endocannabinoid System and Postnatal Neurodevelopment. 2025, 83-112. DOI: 10.1007/978-3-031-87990-6_5.Peer-Reviewed Original ResearchStress-related disordersECB systemResilience to stress-related disordersMaturation of neuronal populationsResponse to stressECB signalingECB levelsFunctional connectivityHuman literaturePostnatal neurodevelopmentNeuronal populationsECBDisordersHuman studiesInfluence riskNeurodevelopmentEndocannabinoidAnxietyEndocrine systemRiskSignaling systemPotential riskYouthAdultsExposure to unpredictable childhood environments is associated with amygdala activation during early extinction in adulthood
Duda J, Keding T, Kribakaran S, Odriozola P, Kitt E, Cohodes E, Zacharek S, McCauley S, Haberman J, Joormann J, Gee D. Exposure to unpredictable childhood environments is associated with amygdala activation during early extinction in adulthood. Developmental Cognitive Neuroscience 2025, 74: 101578. PMID: 40493990, PMCID: PMC12179744, DOI: 10.1016/j.dcn.2025.101578.Peer-Reviewed Original ResearchUnpredictable childhood environmentsChildhood unpredictabilityExtinction learningAmygdala activationChildhood environmentAssociated with amygdala activationBasolateral amygdala activityChildhood trauma exposureSkin conductance responsesCross-species researchThreat cuesTrauma exposureNeural regionsSafety learningEarly adversityHealthy young adultsCurrent anxietyAssociated with activationConductance responsesCaregiving environmentAffective functioningHealthy neurodevelopmentNeural activityTargeted clinical interventionsIn adulthoodLongitudinal and Geographic Trends in Perceived Racial Discrimination Among Adolescents in the United States: The Adolescent Brain Cognitive Development Study
Fields C, Black C, Calhoun A, Rosenblatt M, Rodriguez R, Aina J, Thind J, Grayson J, Khalifa F, Assari S, Zhou X, Nagata J, Gee D. Longitudinal and Geographic Trends in Perceived Racial Discrimination Among Adolescents in the United States: The Adolescent Brain Cognitive Development Study. Journal Of Adolescent Health 2025, 77: 118-127. PMID: 40382724, DOI: 10.1016/j.jadohealth.2025.03.014.Peer-Reviewed Original ResearchConceptsNon-Hispanic youthPerceived discriminationDevelopment studiesHigher levels of perceived discriminationAmerican Community SurveyAnti-Black biasLevels of perceived discriminationPacific IslandersPerceived Discrimination ScaleWhite non-Hispanic youthNeighborhood segregationBlack householdsBlack youthContext-specific approachImmigrant backgroundPerceived racial discriminationRacial discriminationCommunity SurveyRacial biasYouthGeographic variationStructural contextAdolescent Brain Cognitive Development StudyNational representativesRacial/ethnic groupsValidation of an Electronic Self-Administered Version of the Dimensional Inventory of Stress and Trauma Across the Lifespan in a Large Sample of Young Adults
Cohodes E, Mandell J, Notti M, Schroeder M, Ababio R, McCauley S, Pierre J, Hodges H, Gee D. Validation of an Electronic Self-Administered Version of the Dimensional Inventory of Stress and Trauma Across the Lifespan in a Large Sample of Young Adults. Psychological Trauma Theory Research Practice And Policy 2025, 17: 813-820. PMID: 37956029, PMCID: PMC11089071, DOI: 10.1037/tra0001606.Peer-Reviewed Original Research11. Reduced Centromedial Amygdala Recruitment in Youth Independently Regulating Fear During a Parent-Focused Treatment for Pediatric Anxiety
Keding T, Kitt E, Broussard A, Ho G, Weeks G, Zacharek S, Nardini C, Hommel G, Marin C, Silverman W, Lebowitz E, Gee D. 11. Reduced Centromedial Amygdala Recruitment in Youth Independently Regulating Fear During a Parent-Focused Treatment for Pediatric Anxiety. Biological Psychiatry 2025, 97: s78. DOI: 10.1016/j.biopsych.2025.02.201.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
News
News
- June 24, 2025
Announcing the Center for Brain & Mind Health 2025 Pilot Grant Program Awardees
- March 05, 2025Source: Yale News
For Some, Childhood Adversity Can Promote Resilience to Anxiety Disorders
- January 08, 2025
Study Led by Gee Named a 2024 Leading Research Achievement by BBRF
- June 10, 2024
Yale Child Study Center welcomes 2024 summer interns
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