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Yale Cocaine Research Clinic


The Cocaine Research Clinic studies the causes and consequences of cocaine addiction in order to develop improved treatments and, ultimately, to prevent addiction to the drug.
Our research is nationally recognized, and we have active studies in the following areas:

  • Genetics of addiction
  • Brain imaging (PET, MRI)
  • Psychopharmacology
  • Medications Development
  • Sleep and Cognition

Who is eligible?

Treatment and non-treatment seeking individuals who are now using or have used cocaine in the past are potentially eligible.

Contact Us

For more information about the clinic and our research programs, please call Marcella M. Mignosa at 203-903-7795.


  • Assistant Professor of Psychiatry; Director, Yale Cocaine Research Clinic, Psychiatry; Inpatient Chief of the Clinical Neuroscience Research Unit (CNRU), Psychiatry; Medical Director, Forensic Drug Diversion Clinic (ForDD)

  • Professor of Psychiatry and of Neuroscience and of Radiology and Biomedical Imaging; Co-Director of the T32 Translational Alcohol Research Program, Psychiatry and Public Health

  • Associate Professor of Radiology and Biomedical Imaging; Director, NeuroPET Imaging Program, Radiology and Biomedical Imaging; Medical Director, Yale Positron Emission Tomography (PET) Center

  • Steven M. Southwick Professor of Psychiatry and Professor in the Child Study Center and of Neuroscience; Director, Center of Excellence in Gambling Research; Director, Yale Program for Research on Impulsivity and Impulse Control Disorders; Director, Women and Addictive Disorders, Women's Health Research at Yale


Clinical Neuroscience Research Unit (3rd Floor)

Connecticut Mental Health Center
34 Park Street
New Haven, CT 06519