Yale researchers have introduced countless medical and health advances over the last century, including the first success with antibiotics in the United States and the first use of chemotherapy to treat cancer. University scientists have been responsible for the identification of Lyme disease and the discovery of genes responsible for high blood pressure, osteoporosis, dyslexia, and Tourette's syndrome, among other disorders. Early work on the artificial heart and the creation of the first insulin pump took place at Yale, as did seminal discoveries about how the cell and its components function at the molecular level. Today, research activities take place in a wide range of departments, programs, and centers.

The School of Medicine has extraordinary strength in the basic sciences and consistently ranks in the top handful of medical schools receiving funding from the National Institutes of Health. Yale scientists have made seminal discoveries in many fields:

Core Research Facilities

Yale School of Medicine’s core research facilities offer investigators a wide range of state-of-the art instrumentation and technologies for basic, translational, and clinical research.

A tissue culture room in The Anlyan Center forms the backdrop for an impromptu lesson in experiment design. The notes outline experiments to characterize the cellular and molecular mechanisms governing excretion of substances in the urine, particularly oxalate, which predispose to kidney stones when present at high concentrations in the urine.