Research

The Yale Interventional Psychiatry Service is conducting a range of clinical trials using treatments such as Transcranial Magnetic Stimulation (TMS), Esketamine, Magnetic Seizure Therapy (MST), and Electroconvulsive Therapy (ECT).

Interventional Psychiatry Clinical Trials

Alzheimer's Disease, Mental Health & Behavioral ResearchKetamine for the Treatment of Depression in Parkinson's DiseasePrincipal Investigator: Sophie E Holmes
Mental Health & Behavioral ResearchCBT-ENDURE: Cognitive Behavioral Therapy following Esketamine for Major Depression and Suicidal Ideation for Relapse PreventionPrincipal Investigator: Samuel Wilkinson
Not accepting volunteers
Mental Health & Behavioral ResearchAn open-label, feasibility study of the tolerability and usability of a digital application to deliver targeted cognitive behavioral therapy, in addition to treatment as usual, to patients recently hospitalized for suicidal ideation or suicide attemptsPrincipal Investigator: Samuel Wilkinson
Not accepting volunteers

Publications

Efficacy and Safety of Ketamine/Esketamine in Bipolar Depression in a Clinical Setting.Santucci MC, Ansari M, Nikayin S, Radhakrishnan R, Rhee TG, Wilkinson ST. J Clin Psychiatry. 2024 Oct 2; 2024 Oct 2. PMID: 39361411.
Ageism in the Mental Health Setting.Dix E, Van Dyck L, Adeyemo S, Blazek M, Lehmann SW, Singh E, Wilkins K. Curr Psychiatry Rep. 2024 Sep 16; 2024 Sep 16. PMID: 39278983.
Blood pressure changes during ketamine infusion for the treatment of depression.Ansari M, Pittman B, Tylee DS, Ostroff R, Wilkinson ST, Nikayin S. Gen Hosp Psychiatry. 2024 Sep-Oct; 2024 Jul 4. PMID: 38991311.
Substance use and spine density: a systematic review and meta-analysis of preclinical studies.Oliva HNP, Prudente TP, Nunes EJ, Cosgrove KP, Radhakrishnan R, Potenza MN, Angarita GA. Mol Psychiatry. 2024 Sep; 2024 Apr 2. PMID: 38561468.
Hepatitis C Virus Reinfection Among People Who Inject Drugs: Long-Term Follow-Up of the HERO Study.Litwin AH, Tsui JI, Heo M, Mehta SH, Taylor LE, Lum PJ, Feinberg J, Kim AY, Norton BL, Pericot-Valverde I, Arnsten J, Meissner P, Karasz A, McKee MD, Ward JW, Johnson N, Agyemang L, Stein ES, Thomas A, Borsuk C, Blalock KL, Wilkinson S, Wagner K, Carty J, Murray-Krezan C, Anderson J, Jacobsohn V, Luetkemeyer AF, Falade-Nwulia O, Groome M, Davies S, Costello K, Page K. JAMA Netw Open. 2024 Aug 1; 2024 Aug 1. PMID: 39186268.
Enhancing Brain Health and Well-Being in Older Adults: Innovations in Lifestyle Interventions.Beyer JL, Dix E, Husain-Krautter S, Kyomen HH. Curr Psychiatry Rep. 2024 Aug; 2024 Jun 6. PMID: 38842654.
Ketamine vs Electroconvulsive Therapy for Treatment-Resistant Depression: A Secondary Analysis of a Randomized Clinical Trial.Jha MK, Wilkinson ST, Krishnan K, Collins KA, Sanacora G, Murrough J, Goes F, Altinay M, Aloysi A, Asghar-Ali A, Barnett B, Chang L, Costi S, Malone D, Nikayin S, Nissen SE, Ostroff R, Reti I, Wolski K, Wang D, Hu B, Mathew SJ, Anand A. JAMA Netw Open. 2024 Jun 3; 2024 Jun 3. PMID: 38916891.
In Vivo Synaptic Density in Early Schizophrenia: Are There No Differences or Are They Too Small to Detect?Radhakrishnan R. Biol Psychiatry. 2024 Apr 1. PMID: 38479976.
The Rapidly Shifting Ketamine Landscape in the US.Wilkinson ST, Palamar JJ, Sanacora G. JAMA Psychiatry. 2024 Mar 1. PMID: 38170542.
Engaging Historically Black Undergraduate Students in Geriatric Mental Health.Hoskins TF, Smith AT, McWilliams XA, Cox KL, Morgan R, Joshi P, Dix E, Kapoor A, Hendrie K, Perez-Palmer N, Kozar V, Black C. Am J Geriatr Psychiatry. 2024 Mar; 2023 Dec 21. PMID: 38143190.
The regional pattern of age-related synaptic loss in the human brain differs from gray matter volume loss: in vivo PET measurement with [(11)C]UCB-J.Toyonaga T, Khattar N, Wu Y, Lu Y, Naganawa M, Gallezot JD, Matuskey D, Mecca AP, Pittman B, Dias M, Nabulsi NB, Finnema SJ, Chen MK, Arnsten A, Radhakrishnan R, Skosnik PD, D'Souza DC, Esterlis I, Huang Y, van Dyck CH, Carson RE. Eur J Nucl Med Mol Imaging. 2024 Mar; 2023 Nov 13. PMID: 37955791.
A systematic review of approaches to improve medication adherence in homeless adults with psychiatric disorders.Hird R, Radhakrishnan R, Tsai J. Front Psychiatry. 2023; 2024 Jan 8. PMID: 38260790.
Systems that promote mental health in the teeth of oppression.Fullilove MT, Dix E, Hankerson SH, Lassiter J, Jordan A. Lancet Psychiatry. 2024 Jan. PMID: 38101874.
Ketamine and the neurobiology of depression: Toward next-generation rapid-acting antidepressant treatments.Krystal JH, Kaye AP, Jefferson S, Girgenti MJ, Wilkinson ST, Sanacora G, Esterlis I. Proc Natl Acad Sci U S A. 2023 Dec 5; 2023 Nov 27. PMID: 38011560.
Cognitive behavioral therapy following esketamine for major depression and suicidal ideation for relapse prevention: The CBT-ENDURE randomized clinical trial study protocol.Kitay BM, Murphy E, Macaluso M, Corlett PR, Hershenberg R, Joormann J, Martinez-Kaigi V, Nikayin S, Rhee TG, Sanacora G, Shelton RC, Thase ME, Wilkinson ST. Psychiatry Res. 2023 Dec; 2023 Oct 30. PMID: 37935086.
Psychedelic renaissance: Revitalized potential therapies for psychiatric disorders.Rhee TG, Davoudian PA, Sanacora G, Wilkinson ST. Drug Discov Today. 2023 Dec; 2023 Nov 2. PMID: 37925136.
Using latent profile analyses to classify subjects with anhedonia based on reward-related measures obtained in the FAST-MAS study.Darrow SM, Pizzagalli DA, Smoski M, Mathew SJ, Nurnberger J Jr, Lisanby SH, Iosifescu D, Murrough JW, Yang H, Weiner RD, Sanacora G, Keefe RSE, Song A, Goodman W, Whitton AE, Potter WZ, Krystal AD. J Affect Disord. 2023 Oct 15; 2023 Jul 17. PMID: 37467805.
Treatment-resistant depression: definition, prevalence, detection, management, and investigational interventions.McIntyre RS, Alsuwaidan M, Baune BT, Berk M, Demyttenaere K, Goldberg JF, Gorwood P, Ho R, Kasper S, Kennedy SH, Ly-Uson J, Mansur RB, McAllister-Williams RH, Murrough JW, Nemeroff CB, Nierenberg AA, Rosenblat JD, Sanacora G, Schatzberg AF, Shelton R, Stahl SM, Trivedi MH, Vieta E, Vinberg M, Williams N, Young AH, Maj M. World Psychiatry. 2023 Oct. PMID: 37713549.
Single-Dose Psilocybin Treatment for Major Depressive Disorder: A Randomized Clinical Trial.Raison CL, Sanacora G, Woolley J, Heinzerling K, Dunlop BW, Brown RT, Kakar R, Hassman M, Trivedi RP, Robison R, Gukasyan N, Nayak SM, Hu X, O'Donnell KC, Kelmendi B, Sloshower J, Penn AD, Bradley E, Kelly DF, Mletzko T, Nicholas CR, Hutson PR, Tarpley G, Utzinger M, Lenoch K, Warchol K, Gapasin T, Davis MC, Nelson-Douthit C, Wilson S, Brown C, Linton W, Ross S, Griffiths RR. JAMA. 2023 Sep 5. PMID: 37651119.
Substance Use Disorder and Health Outcomes in COVID-19-The Need for a Better Research Method to Determine Substance Use Exposure.Christian NJ, Zhou X, Radhakrishnan R. JAMA Psychiatry. 2023 Sep 1. PMID: 37405794.
The Intricate Interaction Between Expectations and Therapeutic Outcomes of Psychedelic Agents.Colloca L, Nikayin S, Sanacora G. JAMA Psychiatry. 2023 Sep 1. PMID: 37405764.
Bidirectional relationships between cannabis use, anxiety and depressive symptoms in the mediation of the association with psychotic experience: further support for an affective pathway to psychosis.Radhakrishnan R, Pries LK, Erzin G, Ten Have M, de Graaf R, van Dorsselaer S, Gunther N, Bak M, Rutten BPF, van Os J, Guloksuz S. Psychol Med. 2023 Sep; 2022 Sep 12. PMID: 36093677.
Efficacy and Safety of Esketamine Nasal Spray in Patients with Treatment-Resistant Depression Who Completed a Second Induction Period: Analysis of the Ongoing SUSTAIN-3 Study.Castro M, Wilkinson ST, Al Jurdi RK, Petrillo MP, Zaki N, Borentain S, Fu DJ, Turkoz I, Sun L, Brown B, Cabrera P. CNS Drugs. 2023 Aug; 2023 Aug 9. PMID: 37558912.
A leaky umbrella has little value: evidence clearly indicates the serotonin system is implicated in depression.Jauhar S, Arnone D, Baldwin DS, Bloomfield M, Browning M, Cleare AJ, Corlett P, Deakin JFW, Erritzoe D, Fu C, Fusar-Poli P, Goodwin GM, Hayes J, Howard R, Howes OD, Juruena MF, Lam RW, Lawrie SM, McAllister-Williams H, Marwaha S, Matuskey D, McCutcheon RA, Nutt DJ, Pariante C, Pillinger T, Radhakrishnan R, Rucker J, Selvaraj S, Stokes P, Upthegrove R, Yalin N, Yatham L, Young AH, Zahn R, Cowen PJ. Mol Psychiatry. 2023 Aug; 2023 Jun 16. PMID: 37322065.
International perspective on physician knowledge, attitude and practices related to medical cannabis.Syed SA, Singh J, Elkholy H, Palavra IR, Tomicevic M, Eric AP, da Costa MP, Guloksuz S, Radhakrishnan R. medRxiv. 2023 Jul 27; 2023 Jul 27. PMID: 37546945.
Impact of personal beliefs about medical cannabis on physician recommendation practices: Results of an international survey.Syed SA, Singh J, Elkholy H, Rojnić Palavra I, Tomicevic M, Eric AP, Pinto da Costa M, Guloksuz S, Radhakrishnan R. Asian J Psychiatr. 2023 Jul; 2023 May 19. PMID: 37257363.
Trends in Illicit Ketamine Seizures in the US From 2017 to 2022.Palamar JJ, Wilkinson ST, Carr TH, Rutherford C, Cottler LB. JAMA Psychiatry. 2023 Jul 1. PMID: 37223891.
Long-term safety and maintenance of response with esketamine nasal spray in participants with treatment-resistant depression: interim results of the SUSTAIN-3 study.Zaki N, Chen LN, Lane R, Doherty T, Drevets WC, Morrison RL, Sanacora G, Wilkinson ST, Popova V, Fu DJ. Neuropsychopharmacology. 2023 Jul; 2023 May 12. PMID: 37173512.
Ketamine versus ECT for Nonpsychotic Treatment-Resistant Major Depression.Anand A, Mathew SJ, Sanacora G, Murrough JW, Goes FS, Altinay M, Aloysi AS, Asghar-Ali AA, Barnett BS, Chang LC, Collins KA, Costi S, Iqbal S, Jha MK, Krishnan K, Malone DA, Nikayin S, Nissen SE, Ostroff RB, Reti IM, Wilkinson ST, Wolski K, Hu B. N Engl J Med. 2023 Jun 22; 2023 May 24. PMID: 37224232.
Differences in Quantification of the Metabotropic Glutamate Receptor 5 Across Bipolar Disorder and Major Depressive Disorder.Holmes SE, Asch RH, Davis MT, DellaGioia N, Pashankar N, Gallezot JD, Nabulsi N, Matuskey D, Sanacora G, Carson RE, Blumberg HP, Esterlis I. Biol Psychiatry. 2023 Jun 15; 2022 Nov 8. PMID: 36764853.
Candidate biomarkers in psychiatric disorders: state of the field.Abi-Dargham A, Moeller SJ, Ali F, DeLorenzo C, Domschke K, Horga G, Jutla A, Kotov R, Paulus MP, Rubio JM, Sanacora G, Veenstra-VanderWeele J, Krystal JH. World Psychiatry. 2023 Jun. PMID: 37159365.
The Role of Psychotherapy in the Management of Treatment-Resistant Depression.Rogan T, Wilkinson ST. Psychiatr Clin North Am. 2023 Jun; 2023 Mar 15. PMID: 37149349.
Role of Psychedelics in Treatment-Resistant Depression.Kamal S, Jha MK, Radhakrishnan R. Psychiatr Clin North Am. 2023 Jun; 2023 Mar 25. PMID: 37149346.
Arketamine as adjunctive therapy for treatment-resistant depression: A placebo-controlled pilot study.Leal GC, Souza-Marques B, Mello RP, Bandeira ID, Caliman-Fontes AT, Carneiro BA, Faria-Guimarães D, Guerreiro-Costa LNF, Jesus-Nunes AP, Silva SS, Lins-Silva DH, Fontes MA, Alves-Pereira R, Cordeiro V, Rugieri-Pacheco S, Santos-Lima C, Correia-Melo FS, Vieira F, Sanacora G, Lacerda ALT, Quarantini LC. J Affect Disord. 2023 Jun 1; 2023 Mar 4. PMID: 36871913.
Predictors of response and remission in patients with treatment-resistant depression: A post hoc pooled analysis of two acute trials of esketamine nasal spray.Turkoz I, Nelson JC, Wilkinson ST, Borentain S, Macaluso M, Trivedi MH, Williamson D, Sheehan JJ, Salvadore G, Singh J, Daly E. Psychiatry Res. 2023 May; 2023 Mar 16. PMID: 37019044.
Pharmacological and Somatic Treatment Effects on Suicide in Adults: A Systematic Review and Meta-Analysis.Wilkinson ST, Trujillo Diaz D, Rupp ZW, Kidambi A, Ramirez KL, Flores JM, Avila-Quintero VJ, Rhee TG, Olfson M, Bloch MH. Focus (Am Psychiatr Publ). 2023 Apr; 2023 Apr 14. PMID: 37201149.
Prophylactic Efficacy of Riluzole against Anxiety- and Depressive-Like Behaviors in Two Rodent Stress Models.Bansal Y, Fee C, Misquitta KA, Codeluppi SA, Sibille E, Berman RM, Coric V, Sanacora G, Banasr M. Complex Psychiatry. 2023 Jan-Dec; 2023 Feb 3. PMID: 37101541.
Effects of Electroconvulsive Therapy on Functional Outcomes Among Medicare Patients With Comorbid Depression and Dementia: A Nationwide 1-Year Follow-Up Study.Wilkinson ST, Sint K, Forester BP, Rhee TG. J Clin Psychiatry. 2023 Jan 25; 2023 Jan 25. PMID: 36700843.
COVID-19: Brain Effects.Dix E, Roy K. Psychiatr Clin North Am. 2022 Dec; 2022 Jul 6. PMID: 36396269.
Patient-centred models of hepatitis C treatment for people who inject drugs: a multicentre, pragmatic randomised trial.Litwin AH, Lum PJ, Taylor LE, Mehta SH, Tsui JI, Feinberg J, Kim AY, Norton BL, Heo M, Arnsten J, Meissner P, Karasz A, Mckee MD, Ward JW, Johnson N, Pericot-Valverde I, Agyemang L, Stein ES, Thomas A, Borsuk C, Blalock KL, Wilkinson S, Wagner K, Roche J, Murray-Krezan C, Anderson J, Jacobsohn V, Luetkemeyer AF, Falade-Nwulia O, Page K. Lancet Gastroenterol Hepatol. 2022 Dec. PMID: 36370741.
Efficacy and Safety of Ketamine vs Electroconvulsive Therapy Among Patients With Major Depressive Episode: A Systematic Review and Meta-analysis.Rhee TG, Shim SR, Forester BP, Nierenberg AA, McIntyre RS, Papakostas GI, Krystal JH, Sanacora G, Wilkinson ST. JAMA Psychiatry. 2022 Dec 1. PMID: 36260324.
Age, gender and body-mass-index relationships with in vivo CB(1) receptor availability in healthy humans measured with [(11)C]OMAR PET.Radhakrishnan R, Worhunsky PD, Zheng MQ, Najafzadeh S, Gallezot JD, Planeta B, Henry S, Nabulsi N, Ranganathan M, Skosnik PD, Pittman B, Cyril D'Souza D, Carson RE, Huang Y, Potenza MN, Matuskey D. Neuroimage. 2022 Dec 1; 2022 Oct 13. PMID: 36243269.
International pooled patient-level meta-analysis of ketamine infusion for depression: In search of clinical moderators.Price RB, Kissel N, Baumeister A, Rohac R, Woody ML, Ballard ED, Zarate CA Jr, Deakin W, Abdallah CG, Feder A, Charney DS, Grunebaum MF, Mann JJ, Mathew SJ, Gallagher B, McLoughlin DM, Murrough JW, Muthukumaraswamy S, McMillan R, Sumner R, Papakostas G, Fava M, Hock R, Phillips JL, Blier P, Shiroma P, Šóš P, Su TP, Chen MH, Tiger M, Lundberg J, Wilkinson ST, Wallace ML. Mol Psychiatry. 2022 Dec; 2022 Sep 7. PMID: 36071111.
At-home ketamine; still a lot to learn.Wilkinson ST, Sanacora G. J Affect Disord. 2022 Dec 1; 2022 Sep 5. PMID: 36067887.
Effect of Concomitant Benzodiazepines on the Antidepressant Effects of Ketamine: Findings From the RAPID Intravenous Ketamine Study.Feeney A, Hoeppner BB, Freeman MP, Flynn M, Iosifescu DV, Trivedi MH, Sanacora G, Mathew SJ, DeBattista C, Ionescu DF, Cusin C, Papakostas GI, Jha MK, Fava M. J Clin Psychiatry. 2022 Nov 14; 2022 Nov 14. PMID: 36383742.
A Participant-Level Integrative Data Analysis of Differential Placebo Response for Suicidal Ideation and Nonsuicidal Depressive Symptoms in Clinical Trials of Intravenous Racemic Ketamine.Bloomfield-Clagett B, Ballard ED, Greenstein DK, Wilkinson ST, Grunebaum MF, Murrough JW, Mathew SJ, Phillips JL, Fava M, Sanacora G, Zarate CA. Int J Neuropsychopharmacol. 2022 Oct 25. PMID: 35994774.
The association between cannabis use and facial emotion recognition in schizophrenia, siblings, and healthy controls: Results from the EUGEI study.Fusar-Poli L, Pries LK, van Os J, Radhakrishnan R, Pençe AY, Erzin G, Delespaul P, Kenis G, Luykx JJ, Lin BD, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran EŞ, Kaymak SU, Mihaljevic MM, Andric-Petrovic S, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Üçok A, Alptekin K, Saka MC, Aguglia E, Arango C, Rutten BP, Guloksuz S. Eur Neuropsychopharmacol. 2022 Oct; 2022 Aug 30. PMID: 36055075.
Ketamine in the Real World: Where Do We Go From Here?Wilkinson ST. J Clin Psychiatry. 2022 Sep 14; 2022 Sep 14. PMID: 36112579.
Brain-phenotype models fail for individuals who defy sample stereotypes.Greene AS, Shen X, Noble S, Horien C, Hahn CA, Arora J, Tokoglu F, Spann MN, Carrión CI, Barron DS, Sanacora G, Srihari VH, Woods SW, Scheinost D, Constable RT. Nature. 2022 Sep; 2022 Aug 24. PMID: 36002572.
Catatonia After COVID-19: A Case Series.Nikayin S, Chaffkin J, Ostroff RB. J ECT. 2022 Sep 1; 2022 Mar 1. PMID: 35220361.
Impact of Cannabis Use, Substance Use Disorders, and Psychiatric Diagnoses on COVID-19 Outcomes: A Retrospective Cohort Study.Ramakrishnan D, Sureshanand S, Pittman B, Radhakrishnan R. J Clin Psychiatry. 2022 Aug 29; 2022 Aug 29. PMID: 36044600.
Treatment response to esketamine nasal spray in patients with major depressive disorder and acute suicidal ideation or behavior without evidence of early response: a pooled post hoc analysis of ASPIRE.Turkoz I, Lopena O, Salvadore G, Sanacora G, Shelton R, Fu DJ. CNS Spectr. 2022 Jul 29; 2022 Jul 29. PMID: 35904046.
Evaluation of the Trajectory of Depression Severity With Ketamine and Esketamine Treatment in a Clinical Setting.Nikayin S, Rhee TG, Cunningham ME, de Fontnouvelle CA, Ostroff RB, Sanacora G, Wilkinson ST. JAMA Psychiatry. 2022 Jul 1. PMID: 35544190.
Long-term safety of ketamine and esketamine in treatment of depression.Nikayin S, Murphy E, Krystal JH, Wilkinson ST. Expert Opin Drug Saf. 2022 Jun; 2022 Apr 19. PMID: 35416105.
A Novel Biomarker of Neuronal Glutamate Metabolism in Nonhuman Primates Using Localized (1)H-Magnetic Resonance Spectroscopy: Development and Effects of BNC375, an α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator.Miller CO, Gantert LT, Previs SF, Chen Y, Anderson KD, Thomas JM, Sanacora G, Uslaner JM, Rothman DL, Mason GF. Biol Psychiatry Cogn Neurosci Neuroimaging. 2022 Jun; 2020 Sep 29. PMID: 33309567.
An Update on Community Ketamine Practices.O'Brien B, Wilkinson ST, Mathew SJ. Am J Psychiatry. 2022 May. PMID: 35491568.
A Choice-Based Conjoint Analysis of the Psychiatrist Decision-Making Process Used in Determining When to Discharge Adults With Major Depressive Disorder Hospitalized for Active Suicidal Ideation With Intent.Voelker J, Wilkinson ST, Katz EG, Nash AI, Daly E, Ali A, Lovink A, Stahl J, Desai A, Kuvadia H, Neslusan C, Sheehan JJ. J Nerv Ment Dis. 2022 May 1. PMID: 34937847.
Comparison of Long-Term Efficacy and Safety of Esketamine Nasal Spray Plus Oral Antidepressant in Younger Versus Older Patients With Treatment-Resistant Depression: Post-Hoc Analysis of SUSTAIN-2, a Long-Term Open-Label Phase 3 Safety and Efficacy Study.Ochs-Ross R, Wajs E, Daly EJ, Zhang Y, Lane R, Lim P, Drevets WC, Steffens DC, Sanacora G, Jamieson C, Hough D, Manji H, Singh JB. Am J Geriatr Psychiatry. 2022 May; 2021 Oct 6. PMID: 34750057.
mTORC1 inhibitor effects on rapid ketamine-induced reductions in suicidal ideation in patients with treatment-resistant depression.Averill LA, Averill CL, Gueorguieva R, Fouda S, Sherif M, Ahn KH, Ranganathan M, D'Souza DC, Southwick SM, Sanacora G, Duman RS, Krystal JH, Abdallah CG. J Affect Disord. 2022 Apr 15; 2022 Jan 29. PMID: 35101523.
Prefrontal Glutamate Neurotransmission in PTSD: A Novel Approach to Estimate Synaptic Strength in Vivo in Humans.Averill LA, Jiang L, Purohit P, Coppoli A, Averill CL, Roscoe J, Kelmendi B, De Feyter HM, de Graaf RA, Gueorguieva R, Sanacora G, Krystal JH, Rothman DL, Mason GF, Abdallah CG. Chronic Stress (Thousand Oaks). 2022 Jan-Dec; 2022 Apr 11. PMID: 35434443.
Efficacy of Intravenous Ketamine in Adolescent Treatment-Resistant Depression: A Randomized Midazolam-Controlled Trial.Dwyer JB, Landeros-Weisenberger A, Johnson JA, Londono Tobon A, Flores JM, Nasir M, Couloures K, Sanacora G, Bloch MH. Focus (Am Psychiatr Publ). 2022 Apr; 2022 Apr 22. PMID: 37153136.
Imaging the effect of ketamine on synaptic density (SV2A) in the living brain.Holmes SE, Finnema SJ, Naganawa M, DellaGioia N, Holden D, Fowles K, Davis M, Ropchan J, Emory P, Ye Y, Nabulsi N, Matuskey D, Angarita GA, Pietrzak RH, Duman RS, Sanacora G, Krystal JH, Carson RE, Esterlis I. Mol Psychiatry. 2022 Apr; 2022 Feb 15. PMID: 35165397.
Advanced training in interventional psychiatry.Nikayin S, Taylor JJ, Ostroff RB. J Neurol Sci. 2022 Mar 15; 2021 Dec 16. PMID: 34974201.
Ketamine in the Treatment of Obsessive-Compulsive Disorder: A Systematic Review.Bandeira ID, Lins-Silva DH, Cavenaghi VB, Dorea-Bandeira I, Faria-Guimarães D, Barouh JL, Jesus-Nunes AP, Beanes G, Souza LS, Leal GC, Sanacora G, Miguel EC, Sampaio AS, Quarantini LC. Harv Rev Psychiatry. 2022 Mar-Apr 01. PMID: 35267254.
Lower prefrontal cortical synaptic vesicle binding in cocaine use disorder: An exploratory (11) C-UCB-J positron emission tomography study in humans.Angarita GA, Worhunsky PD, Naganawa M, Toyonaga T, Nabulsi NB, Li CR, Esterlis I, Skosnik PD, Radhakrishnan R, Pittman B, Gueorguieva R, Potenza MN, Finnema SJ, Huang Y, Carson RE, Malison RT. Addict Biol. 2022 Mar; 2021 Dec 1. PMID: 34852401.
Editorial: Gone to Pot: Examining the Association Between Cannabis Use and Medical/Psychiatric Disorders.Radhakrishnan R, Guloksuz S, D'Souza DC, van Os J. Front Psychiatry. 2022; 2022 Feb 8. PMID: 35211046.
The stressed synapse 2.0: pathophysiological mechanisms in stress-related neuropsychiatric disorders.Sanacora G, Yan Z, Popoli M. Nat Rev Neurosci. 2022 Feb; 2021 Dec 10. PMID: 34893785.
Pharmacological and somatic treatment effects on suicide in adults: A systematic review and meta-analysis.Wilkinson ST, Trujillo Diaz D, Rupp ZW, Kidambi A, Ramirez KL, Flores JM, Avila-Quintero VJ, Rhee TG, Olfson M, Bloch MH. Depress Anxiety. 2022 Feb; 2021 Nov 11. PMID: 34762330.
Analysis of circulating exosomes reveals a peripheral signature of astrocytic pathology in schizophrenia.Ranganathan M, Rahman M, Ganesh S, D'Souza DC, Skosnik PD, Radhakrishnan R, Pathania S, Mohanakumar T. World J Biol Psychiatry. 2022 Jan; 2021 Apr 28. PMID: 33821753.
Twenty-year trends in use of electroconvulsive therapy among homeless and domiciled veterans with mental illness.Tsai J, Szymkowiak D, Wilkinson ST, Holtzheimer PE. CNS Spectr. 2021 Dec 13; 2021 Dec 13. PMID: 34895380.
Association of ECT With Risks of All-Cause Mortality and Suicide in Older Medicare Patients.Rhee TG, Sint K, Olfson M, Gerhard T, H Busch S, Wilkinson ST. Am J Psychiatry. 2021 Dec; 2021 Sep 10. PMID: 34503341.
Utilization of Electroconvulsive Therapy for Older Homeless Adults Covered by Medicare.Wilkinson ST, Rhee TG, Tsai J. Psychiatr Q. 2021 Dec; 2021 Sep 1. PMID: 34468909.
The Impact of Depression on Outcomes in Patients With Heart Failure and Reduced Ejection Fraction Treated in the GUIDE-IT Trial.Chouairi F, Fuery MA, Mullan CW, Caraballo C, Sen S, Maulion C, Wilkinson ST, Surti T, McCullough M, Miller PE, Pacor J, Leifer ES, Felker GM, Velazquez EJ, Fiuzat M, O'Connor CM, Januzzi JL, Desai NR, Ahmad T. J Card Fail. 2021 Dec; 2021 Jun 22. PMID: 34166799.
In vivo evidence of lower synaptic vesicle density in schizophrenia.Radhakrishnan R, Skosnik PD, Ranganathan M, Naganawa M, Toyonaga T, Finnema S, Hillmer AT, Esterlis I, Huang Y, Nabulsi N, Carson RE, D'Souza DC. Mol Psychiatry. 2021 Dec; 2021 Jun 16. PMID: 34135473.
Evaluating the Role of Ketamine/Esketamine in the Management of Major Depressive Disorder with Suicide Risk.Nikayin S, Sanacora G. CNS Drugs. 2021 Oct; 2021 Sep 7. PMID: 34491545.
Mental Health Care Resource Utilization and Barriers to Receiving Mental Health Services Among US Adults With a Major Depressive Episode and Suicidal Ideation or Behavior With Intent.Voelker J, Cai Q, Daly E, Connolly N, Pesa J, Sheehan JJ, Wilkinson ST. J Clin Psychiatry. 2021 Sep 14; 2021 Sep 14. PMID: 34529898.
Cell-type specific modulation of NMDA receptors triggers antidepressant actions.Pothula S, Kato T, Liu RJ, Wu M, Gerhard D, Shinohara R, Sliby AN, Chowdhury GMI, Behar KL, Sanacora G, Banerjee P, Duman RS. Mol Psychiatry. 2021 Sep; 2020 Jun 2. PMID: 32488125.
The Networked Computer Metaphor: A Novel Tool for Psychiatric Trainees to Enhance Utility of the Biopsychosocial Model of Health and Illness.Balan S, Majumder P, Radhakrishnan R, Wadhwa R, Somvanshi S. Cureus. 2021 Aug; 2021 Aug 23. PMID: 34462709.
Identifying brain networks in synaptic density PET ((11)C-UCB-J) with independent component analysis.Fang XT, Toyonaga T, Hillmer AT, Matuskey D, Holmes SE, Radhakrishnan R, Mecca AP, van Dyck CH, D'Souza DC, Esterlis I, Worhunsky PD, Carson RE. Neuroimage. 2021 Aug 15; 2021 May 15. PMID: 34000404.
The effect of single administration of intravenous ketamine augmentation on suicidal ideation in treatment-resistant unipolar depression: Results from a randomized double-blind study.Feeney A, Hock RS, Freeman MP, Flynn M, Hoeppner B, Iosifescu DV, Trivedi MH, Sanacora G, Mathew SJ, Debattista C, Ionescu DF, Fava M, Papakostas GI. Eur Neuropsychopharmacol. 2021 Aug; 2021 Jun 3. PMID: 34090255.
Treatment Response With Esketamine Nasal Spray Plus an Oral Antidepressant in Patients With Treatment-Resistant Depression Without Evidence of Early Response: A Pooled Post Hoc Analysis of the TRANSFORM Studies.Turkoz I, Daly E, Singh J, Lin X, Tymofyeyev Y, Williamson D, Salvadore G, Nash AI, Macaluso M, Wilkinson ST, Nelson JC. J Clin Psychiatry. 2021 Jul 20; 2021 Jul 20. PMID: 34288609.
Macro- and Microscale Stress-Associated Alterations in Brain Structure: Translational Link With Depression.Banasr M, Sanacora G, Esterlis I. Biol Psychiatry. 2021 Jul 15; 2021 Apr 16. PMID: 34001371.
Need for Ethnic and Population Diversity in Psychosis Research.Burkhard C, Cicek S, Barzilay R, Radhakrishnan R, Guloksuz S. Schizophr Bull. 2021 Jul 8. PMID: 33948664.
A Potential Case of Acute Ketamine Withdrawal: Clinical Implications for the Treatment of Refractory Depression.Roxas N, Ahuja C, Isom J, Wilkinson ST, Capurso N. Am J Psychiatry. 2021 Jul. PMID: 34270337.
Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions.Levey DF, Stein MB, Wendt FR, Pathak GA, Zhou H, Aslan M, Quaden R, Harrington KM, Nuñez YZ, Overstreet C, Radhakrishnan K, Sanacora G, McIntosh AM, Shi J, Shringarpure SS, Concato J, Polimanti R, Gelernter J. Nat Neurosci. 2021 Jul; 2021 May 27. PMID: 34045744.
Preliminary in vivo evidence of lower hippocampal synaptic density in cannabis use disorder.D'Souza DC, Radhakrishnan R, Naganawa M, Ganesh S, Nabulsi N, Najafzadeh S, Ropchan J, Ranganathan M, Cortes-Briones J, Huang Y, Carson RE, Skosnik P. Mol Psychiatry. 2021 Jul; 2020 Sep 24. PMID: 32973170.
Association of Cannabis Use During Adolescence With Neurodevelopment.Albaugh MD, Ottino-Gonzalez J, Sidwell A, Lepage C, Juliano A, Owens MM, Chaarani B, Spechler P, Fontaine N, Rioux P, Lewis L, Jeon S, Evans A, D'Souza D, Radhakrishnan R, Banaschewski T, Bokde ALW, Quinlan EB, Conrod P, Desrivières S, Flor H, Grigis A, Gowland P, Heinz A, Ittermann B, Martinot JL, Paillère Martinot ML, Nees F, Papadopoulos Orfanos D, Paus T, Poustka L, Millenet S, Fröhner JH, Smolka MN, Walter H, Whelan R, Schumann G, Potter A, Garavan H. JAMA Psychiatry. 2021 Jun 16; 2021 Jun 16. PMID: 34132750.
Emerging Therapeutics Based on the Amino Acid Neurotransmitter System: An Update on the Pharmaceutical Pipeline for Mood Disorders.Hecking J, Davoudian PA, Wilkinson ST. Chronic Stress (Thousand Oaks). 2021 Jan-Dec; 2021 Jun 2. PMID: 34124495.
Effect of Social Determinants of Health on Cognition and Risk of Alzheimer Disease and Related Dementias.Majoka MA, Schimming C. Clin Ther. 2021 Jun; 2021 Jun 5. PMID: 34103175.
Exocannabinoids, Endocannabinoids, and Psychosis.Radhakrishnan R, Ranganathan M, Skosnik PD, D'Souza DC. Biol Psychiatry Cogn Neurosci Neuroimaging. 2021 Jun. PMID: 34099185.
Absence seizures and their relationship to depression and anxiety: Evidence for bidirectionality.Gruenbaum BF, Sandhu MRS, Bertasi RAO, Bertasi TGO, Schonwald A, Kurup A, Gruenbaum SE, Freedman IG, Funaro MC, Blumenfeld H, Sanacora G. Epilepsia. 2021 May; 2021 Mar 10. PMID: 33751566.
Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation.McIntyre RS, Rosenblat JD, Nemeroff CB, Sanacora G, Murrough JW, Berk M, Brietzke E, Dodd S, Gorwood P, Ho R, Iosifescu DV, Lopez Jaramillo C, Kasper S, Kratiuk K, Lee JG, Lee Y, Lui LMW, Mansur RB, Papakostas GI, Subramaniapillai M, Thase M, Vieta E, Young AH, Zarate CA Jr, Stahl S. Am J Psychiatry. 2021 May 1; 2021 Mar 17. PMID: 33726522.
Repetitive and Self-injurious Behaviors in Children with Cornelia de Lange Syndrome.Srivastava S, Clark B, Landy-Schmitt C, Offermann EA, Kline AD, Wilkinson ST, Grados MA. J Autism Dev Disord. 2021 May. PMID: 32809170.
Efficacy of Intravenous Ketamine in Adolescent Treatment-Resistant Depression: A Randomized Midazolam-Controlled Trial.Dwyer JB, Landeros-Weisenberger A, Johnson JA, Londono Tobon A, Flores JM, Nasir M, Couloures K, Sanacora G, Bloch MH. Am J Psychiatry. 2021 Apr 1; 2021 Mar 3. PMID: 33653121.
Intravenous arketamine for treatment-resistant depression: open-label pilot study.Leal GC, Bandeira ID, Correia-Melo FS, Telles M, Mello RP, Vieira F, Lima CS, Jesus-Nunes AP, Guerreiro-Costa LNF, Marback RF, Caliman-Fontes AT, Marques BLS, Bezerra MLO, Dias-Neto AL, Silva SS, Sampaio AS, Sanacora G, Turecki G, Loo C, Lacerda ALT, Quarantini LC. Eur Arch Psychiatry Clin Neurosci. 2021 Apr; 2020 Feb 20. PMID: 32078034.
Therapeutic Potential of Psychedelics in Treatment of Psychiatric Disorders, Part 2: Review of the Evidence.Hosanagar A, Cusimano J, Radhakrishnan R. J Clin Psychiatry. 2021 Feb 23; 2021 Feb 23. PMID: 33988930.
Therapeutic Potential of Psychedelics in the Treatment of Psychiatric Disorders, Part 1: Psychopharmacology and Neurobiological Effects.Hosanagar A, Cusimano J, Radhakrishnan R. J Clin Psychiatry. 2021 Feb 23; 2021 Feb 23. PMID: 33988926.
Cognitive Behavioral Therapy to Sustain the Antidepressant Effects of Ketamine in Treatment-Resistant Depression: A Randomized Clinical Trial.Wilkinson ST, Rhee TG, Joormann J, Webler R, Ortiz Lopez M, Kitay B, Fasula M, Elder C, Fenton L, Sanacora G. Psychother Psychosom. 2021; 2021 Jun 29. PMID: 34186531.
Factors associated with health-related quality of life in patients with cirrhosis: a systematic review.Rabiee A, Ximenes RO, Nikayin S, Hickner A, Juthani P, Rosen RH, Garcia-Tsao G. Liver Int. 2021 Jan; 2020 Nov 2. PMID: 32998172.
Antipsychotic Medication Prescriptions for Homeless and Unstably Housed Veterans in the Veterans Affairs Health Care System.Tsai J, Szymkowiak D, Radhakrishnan R. J Clin Psychiatry. 2020 Dec 8; 2020 Dec 8. PMID: 33296148.
Psychosis-Relevant Effects of Intravenous Delta-9-Tetrahydrocannabinol: A Mega Analysis of Individual Participant-Data from Human Laboratory Studies.Ganesh S, Cortes-Briones J, Ranganathan M, Radhakrishnan R, Skosnik PD, D'Souza DC. Int J Neuropsychopharmacol. 2020 Dec 3. PMID: 32385508.
Prevalence of Treatment for Depression Among US Adults Who Screen Positive for Depression, 2007-2016.Rhee TG, Wilkinson ST, Steffens DC, Rosenheck RA, Olfson M. JAMA Psychiatry. 2020 Nov 1. PMID: 32609306.
Changes in pharmacotherapeutic approaches in the treatment of bipolar disorder by primary care physicians.Rhee TG, Olfson M, Wilkinson ST. Gen Hosp Psychiatry. 2020 Nov-Dec; 2020 Mar 14. PMID: 32184005.
Hormonal Treatments for Major Depressive Disorder: State of the Art.Dwyer JB, Aftab A, Radhakrishnan R, Widge A, Rodriguez CI, Carpenter LL, Nemeroff CB, McDonald WM, Kalin NH. Am J Psychiatry. 2020 Aug 1; 2020 May 27. PMID: 32456504.
20-Year Trends in the Pharmacologic Treatment of Bipolar Disorder by Psychiatrists in Outpatient Care Settings.Rhee TG, Olfson M, Nierenberg AA, Wilkinson ST. Am J Psychiatry. 2020 Aug 1; 2020 Apr 21. PMID: 32312111.
Characterization of the Quality of Electroconvulsive Therapy Among Older Medicare Beneficiaries.Rhee TG, Olfson M, Sint K, Wilkinson ST. J Clin Psychiatry. 2020 Jul 7; 2020 Jul 7. PMID: 32659875.
Exploring the Psychiatrist-Industry Financial Relationship: Insight from the Open Payment Data of Centers for Medicare and Medicaid Services.Rhee TG, Wilkinson ST. Adm Policy Ment Health. 2020 Jul. PMID: 31916072.
Correction: Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD).Fava M, Freeman MP, Flynn M, Judge H, Hoeppner BB, Cusin C, Ionescu DF, Mathew SJ, Chang LC, Iosifescu DV, Murrough J, Debattista C, Schatzberg AF, Trivedi MH, Jha MK, Sanacora G, Wilkinson ST, Papakostas GI. Mol Psychiatry. 2020 Jul. PMID: 30617276.
Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD).Fava M, Freeman MP, Flynn M, Judge H, Hoeppner BB, Cusin C, Ionescu DF, Mathew SJ, Chang LC, Iosifescu DV, Murrough J, Debattista C, Schatzberg AF, Trivedi MH, Jha MK, Sanacora G, Wilkinson ST, Papakostas GI. Mol Psychiatry. 2020 Jul; 2018 Oct 3. PMID: 30283029.
Early life stress and glutamate neurotransmission in major depressive disorder.Averill LA, Abdallah CG, Fenton LR, Fasula MK, Jiang L, Rothman DL, Mason GF, Sanacora G. Eur Neuropsychopharmacol. 2020 Jun; 2020 May 15. PMID: 32418842.
A Randomized Controlled Trial of Video Psychoeducation for Electroconvulsive Therapy in the United States.Tsai J, Huang M, Rosenheck RA, Wilkinson S. Psychiatr Serv. 2020 Jun 1; 2020 Mar 10. PMID: 32151214.
Is This Where We Stand After Decades of Research to Develop More Personalized Treatments for Depression?Sanacora G. JAMA Psychiatry. 2020 Jun 1. PMID: 32074267.
Esketamine Nasal Spray for Rapid Reduction of Major Depressive Disorder Symptoms in Patients Who Have Active Suicidal Ideation With Intent: Double-Blind, Randomized Study (ASPIRE I).Fu DJ, Ionescu DF, Li X, Lane R, Lim P, Sanacora G, Hough D, Manji H, Drevets WC, Canuso CM. J Clin Psychiatry. 2020 May 12; 2020 May 12. PMID: 32412700.
Temple-healing in South India.Radhakrishnan R. Indian J Psychiatry. 2020 May-Jun; 2020 May 15. PMID: 32773884.
Body Mass Index as a Moderator of Treatment Response to Ketamine for Major Depressive Disorder.Freeman MP, Hock RS, Papakostas GI, Judge H, Cusin C, Mathew SJ, Sanacora G, Iosifescu DV, DeBattista C, Trivedi MH, Fava M. J Clin Psychopharmacol. 2020 May/Jun. PMID: 32332464.
A randomized proof-of-mechanism trial applying the 'fast-fail' approach to evaluating κ-opioid antagonism as a treatment for anhedonia.Krystal AD, Pizzagalli DA, Smoski M, Mathew SJ, Nurnberger J Jr, Lisanby SH, Iosifescu D, Murrough JW, Yang H, Weiner RD, Calabrese JR, Sanacora G, Hermes G, Keefe RSE, Song A, Goodman W, Szabo ST, Whitton AE, Gao K, Potter WZ. Nat Med. 2020 May; 2020 Mar 30. PMID: 32231295.
Modulation of the antidepressant effects of ketamine by the mTORC1 inhibitor rapamycin.Abdallah CG, Averill LA, Gueorguieva R, Goktas S, Purohit P, Ranganathan M, Sherif M, Ahn KH, D'Souza DC, Formica R, Southwick SM, Duman RS, Sanacora G, Krystal JH. Neuropsychopharmacology. 2020 May; 2020 Feb 24. PMID: 32092760.
Esketamine Nasal Spray Plus Oral Antidepressant in Patients With Treatment-Resistant Depression: Assessment of Long-Term Safety in a Phase 3, Open-Label Study (SUSTAIN-2).Wajs E, Aluisio L, Holder R, Daly EJ, Lane R, Lim P, George JE, Morrison RL, Sanacora G, Young AH, Kasper S, Sulaiman AH, Li CT, Paik JW, Manji H, Hough D, Grunfeld J, Jeon HJ, Wilkinson ST, Drevets WC, Singh JB. J Clin Psychiatry. 2020 Apr 28; 2020 Apr 28. PMID: 32316080.
Psychiatric symptoms caused by cannabis constituents: a systematic review and meta-analysis.Hindley G, Beck K, Borgan F, Ginestet CE, McCutcheon R, Kleinloog D, Ganesh S, Radhakrishnan R, D'Souza DC, Howes OD. Lancet Psychiatry. 2020 Apr; 2020 Mar 17. PMID: 32197092.
Suicide in Older Adults With and Without Known Mental Illness: Results From the National Violent Death Reporting System, 2003-2016.Schmutte TJ, Wilkinson ST. Am J Prev Med. 2020 Apr; 2020 Jan 28. PMID: 32001049.
Effects of video psychoeducation on perceptions and knowledge about electroconvulsive therapy.Tsai J, Huang M, Wilkinson ST, Edelen C. Psychiatry Res. 2020 Feb 3; 2020 Feb 3. PMID: 32192999.
Efficacy and Safety of Esketamine Nasal Spray Plus an Oral Antidepressant in Elderly Patients With Treatment-Resistant Depression-TRANSFORM-3.Ochs-Ross R, Daly EJ, Zhang Y, Lane R, Lim P, Morrison RL, Hough D, Manji H, Drevets WC, Sanacora G, Steffens DC, Adler C, McShane R, Gaillard R, Wilkinson ST, Singh JB. Am J Geriatr Psychiatry. 2020 Feb; 2019 Oct 17. PMID: 31734084.
In vivo 5-HT(6) and 5-HT(2A) receptor availability in antipsychotic treated schizophrenia patients vs. unmedicated healthy humans measured with [(11)C]GSK215083 PET.Radhakrishnan R, Matuskey D, Nabulsi N, Gaiser E, Gallezot JD, Henry S, Planeta B, Lin SF, Ropchan J, Huang Y, Carson RE, D'Souza DC. Psychiatry Res Neuroimaging. 2020 Jan 30; 2019 Nov 12. PMID: 31760336.
Time to relapse after a single administration of intravenous ketamine augmentation in unipolar treatment-resistant depression.Salloum NC, Fava M, Hock RS, Freeman MP, Flynn M, Hoeppner B, Cusin C, Iosifescu DV, Trivedi MH, Sanacora G, Mathew SJ, Debattista C, Ionescu DF, Papakostas GI. J Affect Disord. 2020 Jan 1; 2019 Sep 3. PMID: 31494365.
Associations of sociodemographic and clinical factors with perinatal depression among Israeli women: a cross-sectional study.Adler L, Tsamir J, Katz R, Koren G, Yehoshua I. BMC Psychiatry. 2019 Nov 1; 2019 Nov 1. PMID: 31675947.
Longer-term open-label study of adjunctive riluzole in treatment-resistant depression.Sakurai H, Dording C, Yeung A, Foster S, Jain F, Chang T, Trinh NH, Bernard R, Boyden S, Iqbal SZ, Wilkinson ST, Mathew SJ, Mischoulon D, Fava M, Cusin C. J Affect Disord. 2019 Nov 1; 2019 Jul 2. PMID: 31400624.
Highs and lows of cannabinoid-dopamine interactions: effects of genetic variability and pharmacological modulation of catechol-O-methyl transferase on the acute response to delta-9-tetrahydrocannabinol in humans.Ranganathan M, De Aquino JP, Cortes-Briones JA, Radhakrishnan R, Pittman B, Bhakta S, D'Souza DC. Psychopharmacology (Berl). 2019 Nov; 2019 Jun 11. PMID: 31187152.
Associations of Adverse Childhood Experiences with Past-Year DSM-5 Psychiatric and Substance Use Disorders in Older Adults.Rhee TG, Barry LC, Kuchel GA, Steffens DC, Wilkinson ST. J Am Geriatr Soc. 2019 Oct; 2019 Jun 17. PMID: 31206597.
Psychiatric Practice Patterns and Barriers to the Adoption of Esketamine.Wilkinson ST, Howard DH, Busch SH. JAMA. 2019 Sep 17. PMID: 31373610.
Interaction between environmental and familial affective risk impacts psychosis admixture in states of affective dysregulation.Radhakrishnan R, Guloksuz S, Ten Have M, de Graaf R, van Dorsselaer S, Gunther N, Rauschenberg C, Reininghaus U, Pries LK, Bak M, van Os J. Psychol Med. 2019 Aug; 2018 Oct 4. PMID: 30284529.
Reasoning bias, working memory performance and a transdiagnostic phenotype of affective disturbances and psychotic experiences in the general population.Reininghaus U, Rauschenberg C, Ten Have M, de Graaf R, van Dorsselaer S, Simons CJP, Gunther N, Pries LK, Guloksuz S, Radhakrishnan R, Bak M, van Os J. Psychol Med. 2019 Aug; 2018 Aug 30. PMID: 30160228.
Elevated Unconjugated Bilirubin in Schizophrenia Compared to Bipolar Affective Disorder.Pradeep JR, Acharya MS, Radhakrishnan R, Srinivasan K. Prim Care Companion CNS Disord. 2019 Jul 25; 2019 Jul 25. PMID: 31364826.
Impact of midazolam vs. saline on effect size estimates in controlled trials of ketamine as a rapid-acting antidepressant.Wilkinson ST, Farmer C, Ballard ED, Mathew SJ, Grunebaum MF, Murrough JW, Sos P, Wang G, Gueorguieva R, Zarate CA Jr. Neuropsychopharmacology. 2019 Jun; 2019 Jan 17. PMID: 30653192.
Medical Marijuana: What Physicians Need to Know.Radhakrishnan R, Ranganathan M, D'Souza DC. J Clin Psychiatry. 2019 May 7; 2019 May 7. PMID: 31087827.
Lower synaptic density is associated with depression severity and network alterations.Holmes SE, Scheinost D, Finnema SJ, Naganawa M, Davis MT, DellaGioia N, Nabulsi N, Matuskey D, Angarita GA, Pietrzak RH, Duman RS, Sanacora G, Krystal JH, Carson RE, Esterlis I. Nat Commun. 2019 Apr 4; 2019 Apr 4. PMID: 30948709.
Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments.Duman RS, Sanacora G, Krystal JH. Neuron. 2019 Apr 3. PMID: 30946828.
Leveraging Neuroplasticity to Enhance Adaptive Learning: The Potential for Synergistic Somatic-Behavioral Treatment Combinations to Improve Clinical Outcomes in Depression.Wilkinson ST, Holtzheimer PE, Gao S, Kirwin DS, Price RB. Biol Psychiatry. 2019 Mar 15; 2018 Sep 20. PMID: 30528745.
Ketamine: A Paradigm Shift for Depression Research and Treatment.Krystal JH, Abdallah CG, Sanacora G, Charney DS, Duman RS. Neuron. 2019 Mar 6. PMID: 30844397.
Grey Matter Volume Differences Associated with Extremely Low Levels of Cannabis Use in Adolescence.Orr C, Spechler P, Cao Z, Albaugh M, Chaarani B, Mackey S, D'Souza D, Allgaier N, Banaschewski T, Bokde ALW, Bromberg U, Büchel C, Burke Quinlan E, Conrod P, Desrivières S, Flor H, Frouin V, Gowland P, Heinz A, Ittermann B, Martinot JL, Martinot MP, Nees F, Papadopoulos Orfanos D, Paus T, Poustka L, Millenet S, Fröhner JH, Radhakrishnan R, Smolka MN, Walter H, Whelan R, Schumann G, Potter A, Garavan H. J Neurosci. 2019 Mar 6; 2019 Jan 14. PMID: 30643026.
Caution Against Overinterpreting Opiate Receptor Stimulation as Mediating Antidepressant Effects of Ketamine.Sanacora G. Am J Psychiatry. 2019 Mar 1. PMID: 30818992.
Efficacy of intravenous ketamine treatment in anxious versus nonanxious unipolar treatment-resistant depression.Salloum NC, Fava M, Freeman MP, Flynn M, Hoeppner B, Hock RS, Cusin C, Iosifescu DV, Trivedi MH, Sanacora G, Mathew SJ, Debattista C, Ionescu DF, Papakostas GI. Depress Anxiety. 2019 Mar; 2018 Dec 30. PMID: 30597688.
The Successful Use of Electroconvulsive Therapy in a Patient With Cerebral Aneurysms and a Pituitary Lesion.Kitay BM, Katz RB, Wilkinson ST, Ostroff RB. J ECT. 2019 Mar. PMID: 29952859.
Access to Outpatient Electroconvulsive Therapy at VA Medical Centers - Reply.Wilkinson ST, Rosenheck R. J ECT. 2019 Mar. PMID: 29901498.
ELEctroconvulsive therapy (ECT) vs. Ketamine in patients with Treatment-resistant Depression: The ELEKT-D study protocol.Mathew SJ, Wilkinson ST, Altinay M, Asghar-Ali A, Chang LC, Collins KA, Dale RM, Hu B, Krishnan K, Kellner CH, Malone DA, Murrough JW, Ostroff RB, Sanacora G, Shao M, Anand A. Contemp Clin Trials. 2019 Feb; 2018 Dec 17. PMID: 30572160.
A new generation of antidepressants: an update on the pharmaceutical pipeline for novel and rapid-acting therapeutics in mood disorders based on glutamate/GABA neurotransmitter systems.Wilkinson ST, Sanacora G. Drug Discov Today. 2019 Feb; 2018 Nov 14. PMID: 30447328.
Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of Symptoms of Depression and Suicidality in Patients at Imminent Risk for Suicide: Results of a Double-Blind, Randomized, Placebo-Controlled Study.Canuso CM, Singh JB, Fedgchin M, Alphs L, Lane R, Lim P, Pinter C, Hough D, Sanacora G, Manji H, Drevets WC. Focus (Am Psychiatr Publ). 2019 Jan; 2019 Jan 7. PMID: 32015715.
Efficacy and safety of a fatty acid amide hydrolase inhibitor (PF-04457845) in the treatment of cannabis withdrawal and dependence in men: a double-blind, placebo-controlled, parallel group, phase 2a single-site randomised controlled trial.D'Souza DC, Cortes-Briones J, Creatura G, Bluez G, Thurnauer H, Deaso E, Bielen K, Surti T, Radhakrishnan R, Gupta A, Gupta S, Cahill J, Sherif MA, Makriyannis A, Morgan PT, Ranganathan M, Skosnik PD. Lancet Psychiatry. 2019 Jan; 2018 Dec 6. PMID: 30528676.
Serum and plasma brain-derived neurotrophic factor and response in a randomized controlled trial of riluzole for treatment resistant depression.Wilkinson ST, Kiselycznyk C, Banasr M, Webler RD, Haile C, Mathew SJ. J Affect Disord. 2018 Dec 1; 2018 Aug 18. PMID: 30153634.
The neurobiology of depression, ketamine and rapid-acting antidepressants: Is it glutamate inhibition or activation?Abdallah CG, Sanacora G, Duman RS, Krystal JH. Pharmacol Ther. 2018 Oct; 2018 May 25. PMID: 29803629.
Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU.Devlin JW, Skrobik Y, Gélinas C, Needham DM, Slooter AJC, Pandharipande PP, Watson PL, Weinhouse GL, Nunnally ME, Rochwerg B, Balas MC, van den Boogaard M, Bosma KJ, Brummel NE, Chanques G, Denehy L, Drouot X, Fraser GL, Harris JE, Joffe AM, Kho ME, Kress JP, Lanphere JA, McKinley S, Neufeld KJ, Pisani MA, Payen JF, Pun BT, Puntillo KA, Riker RR, Robinson BRH, Shehabi Y, Szumita PM, Winkelman C, Centofanti JE, Price C, Nikayin S, Misak CJ, Flood PD, Kiedrowski K, Alhazzani W. Crit Care Med. 2018 Sep. PMID: 30113379.
Executive Summary: Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU.Devlin JW, Skrobik Y, Gélinas C, Needham DM, Slooter AJC, Pandharipande PP, Watson PL, Weinhouse GL, Nunnally ME, Rochwerg B, Balas MC, van den Boogaard M, Bosma KJ, Brummel NE, Chanques G, Denehy L, Drouot X, Fraser GL, Harris JE, Joffe AM, Kho ME, Kress JP, Lanphere JA, McKinley S, Neufeld KJ, Pisani MA, Payen JF, Pun BT, Puntillo KA, Riker RR, Robinson BRH, Shehabi Y, Szumita PM, Winkelman C, Centofanti JE, Price C, Nikayin S, Misak CJ, Flood PD, Kiedrowski K, Alhazzani W. Crit Care Med. 2018 Sep. PMID: 30113371.
The effects of ketamine on prefrontal glutamate neurotransmission in healthy and depressed subjects.Abdallah CG, De Feyter HM, Averill LA, Jiang L, Averill CL, Chowdhury GMI, Purohit P, de Graaf RA, Esterlis I, Juchem C, Pittman BP, Krystal JH, Rothman DL, Sanacora G, Mason GF. Neuropsychopharmacology. 2018 Sep; 2018 Jun 28. PMID: 29977074.
The Psychiatric Consequences of Cannabinoids.De Aquino JP, Sherif M, Radhakrishnan R, Cahill JD, Ranganathan M, D'Souza DC. Clin Ther. 2018 Sep; 2018 Apr 17. PMID: 29678279.
Age-Related Change in 5-HT(6) Receptor Availability in Healthy Male Volunteers Measured with (11)C-GSK215083 PET.Radhakrishnan R, Nabulsi N, Gaiser E, Gallezot JD, Henry S, Planeta B, Lin SF, Ropchan J, Williams W, Morris E, D'Souza DC, Huang Y, Carson RE, Matuskey D. J Nucl Med. 2018 Sep; 2018 Apr 6. PMID: 29626125.
Acute and Longer-Term Outcomes Using Ketamine as a Clinical Treatment at the Yale Psychiatric Hospital.Wilkinson ST, Katz RB, Toprak M, Webler R, Ostroff RB, Sanacora G. J Clin Psychiatry. 2018 Jul 24; 2018 Jul 24. PMID: 30063304.
Ketamine: A Review for Clinicians.Sanacora G, Katz R. Focus (Am Psychiatr Publ). 2018 Jul; 2018 Jul 16. PMID: 31975918.
Hopes and Skepticism for Unraveling the Unique Mechanisms of Ketamine's Rapid Onset Antidepressant Actions in Rodent Models.Sanacora G. Biol Psychiatry. 2018 Jul 1. PMID: 29929579.
Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of Symptoms of Depression and Suicidality in Patients at Imminent Risk for Suicide: Results of a Double-Blind, Randomized, Placebo-Controlled Study.Canuso CM, Singh JB, Fedgchin M, Alphs L, Lane R, Lim P, Pinter C, Hough D, Sanacora G, Manji H, Drevets WC. Am J Psychiatry. 2018 Jul 1; 2018 Apr 16. PMID: 29656663.
Evidence That Environmental and Familial Risks for Psychosis Additively Impact a Multidimensional Subthreshold Psychosis Syndrome.Pries LK, Guloksuz S, Ten Have M, de Graaf R, van Dorsselaer S, Gunther N, Rauschenberg C, Reininghaus U, Radhakrishnan R, Bak M, Rutten BPF, van Os J. Schizophr Bull. 2018 Jun 6. PMID: 29701807.
Identifying Recipients of Electroconvulsive Therapy: Data From Privately Insured Americans.Wilkinson ST, Agbese E, Leslie DL, Rosenheck RA. Psychiatr Serv. 2018 May 1; 2018 Feb 1. PMID: 29385954.
Authorship Credit for Large Clinical Trials.Wilkinson ST, Sanacora G. JAMA. 2018 Feb 20. PMID: 29466586.
Acute psychoactive effects of intravenous ketamine during treatment of mood disorders: Analysis of the Clinician Administered Dissociative State Scale.van Schalkwyk GI, Wilkinson ST, Davidson L, Silverman WK, Sanacora G. J Affect Disord. 2018 Feb; 2017 Sep 28. PMID: 29045915.
The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis.Wilkinson ST, Ballard ED, Bloch MH, Mathew SJ, Murrough JW, Feder A, Sos P, Wang G, Zarate CA Jr, Sanacora G. Am J Psychiatry. 2018 Feb 1; 2017 Oct 3. PMID: 28969441.
From "Azalla" to Anandamide: Distilling the Therapeutic Potential of Cannabinoids.Radhakrishnan R, Ross DA. Biol Psychiatry. 2018 Jan 15. PMID: 29223222.
In Reply to Steinhilber et al.Packer CD, Katz RB. Acad Med. 2017 Dec. PMID: 29210743.
2017 in Review.Freedman R, Lewis DA, Michels R, Pine DS, Rush AJ, Schultz SK, Tamminga CA, Katz R. Am J Psychiatry. 2017 Dec 1. PMID: 29191032.
Safe Treatment of a Patient With an Ommaya Reservoir With Electroconvulsive Therapy.Toprak M, Katz RB, Ostroff R. J ECT. 2017 Dec. PMID: 28594737.
A Randomized, Double-Blind, Placebo-Controlled, Sequential Parallel Comparison Design Trial of Adjunctive Riluzole for Treatment-Resistant Major Depressive Disorder.Mathew SJ, Gueorguieva R, Brandt C, Fava M, Sanacora G. Neuropsychopharmacology. 2017 Dec; 2017 May 29. PMID: 28553836.
Tetrahydrocannabinol (THC) impairs encoding but not retrieval of verbal information.Ranganathan M, Radhakrishnan R, Addy PH, Schnakenberg-Martin AM, Williams AH, Carbuto M, Elander J, Pittman B, Andrew Sewell R, Skosnik PD, D'Souza DC. Prog Neuropsychopharmacol Biol Psychiatry. 2017 Oct 3; 2017 Jun 20. PMID: 28642081.
Considerations on the Off-label Use of Ketamine as a Treatment for Mood Disorders.Wilkinson ST, Sanacora G. JAMA. 2017 Sep 5. PMID: 28806440.
Ketamine for the Treatment of Depression-Reply.Sanacora G. JAMA Psychiatry. 2017 Sep 1. PMID: 28700772.
Co-occurring Catatonia and Posterior Reversible Encephalopathy Syndrome Responsive to Electroconvulsive Therapy.Klingensmith KE, Sanacora G, Ostroff R. J ECT. 2017 Sep. PMID: 28383349.
Reply to: Ketamine and Psychosis History: Antidepressant Efficacy and Psychotomimetic Effects Postinfusion.Medeiros da Frota Ribeiro C, Sanacora G, Ostroff R. Biol Psychiatry. 2017 Sep 1; 2017 Jan 23. PMID: 28262251.
Synaptic Loss and the Pathophysiology of PTSD: Implications for Ketamine as a Prototype Novel Therapeutic.Krystal JH, Abdallah CG, Averill LA, Kelmendi B, Harpaz-Rotem I, Sanacora G, Southwick SM, Duman RS. Curr Psychiatry Rep. 2017 Aug 26; 2017 Aug 26. PMID: 28844076.
Metabotropic Glutamate Receptor 5 and Glutamate Involvement in Major Depressive Disorder: A Multimodal Imaging Study.Abdallah CG, Hannestad J, Mason GF, Holmes SE, DellaGioia N, Sanacora G, Jiang L, Matuskey D, Satodiya R, Gasparini F, Lin X, Javitch J, Planeta B, Nabulsi N, Carson RE, Esterlis I. Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Jul; 2017 Apr 6. PMID: 28993818.
The Link Between the Immune System, Environment, and Psychosis.Radhakrishnan R, Kaser M, Guloksuz S. Schizophr Bull. 2017 Jul 1. PMID: 28969353.
A Survey of the Clinical, Off-Label Use of Ketamine as a Treatment for Psychiatric Disorders.Wilkinson ST, Toprak M, Turner MS, Levine SP, Katz RB, Sanacora G. Am J Psychiatry. 2017 Jul 1. PMID: 28669202.
Editorial training models for early-career psychiatrists.Radhakrishnan R, Wasser T, Picon F, Puspanathan P, Pinto da Costa M, Nakamae T, Elkholy H. Lancet Psychiatry. 2017 Jul. PMID: 28652036.
A Successful Course of Electroconvulsive Therapy in a Patient With Epilepsy and a Posterior Fossa Titanium Plate.Katz RB, Toprak M, Ostroff R. J ECT. 2017 Jun. PMID: 28009626.
Effective Research Mentorship for Residents: Meeting the Needs of Early Career Physicians.van Schalkwyk GI, Katz RB, Resignato J, van Schalkwyk SC, Rohrbaugh RM. Acad Psychiatry. 2017 Jun; 2016 Oct 20. PMID: 27766554.
Hippocampal volume changes following electroconvulsive therapy: a systematic review and meta-analysis.Wilkinson ST, Sanacora G, Bloch MH. Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 May; 2017 Feb 5. PMID: 28989984.
Development of a Diverse Learning Experience for Diverse Psychiatry Resident Needs: A Four-Year Biological Psychiatry Curriculum Incorporating Principles of Neurobiology, Psychopharmacology, and Evidence-Based Practice.Muzyk AJ, Gagliardi JP, Rakesh G, Jiroutek MR, Radhakrishnan R, Pae CU, Masand PS, Szabo ST. Psychiatry Investig. 2017 May; 2017 May 16. PMID: 28539947.
Ketamine as a Treatment for Adolescent Depression: A Case Report.Dwyer JB, Beyer C, Wilkinson ST, Ostroff RB, Qayyum Z, Bloch MH. J Am Acad Child Adolesc Psychiatry. 2017 Apr. PMID: 28335880.
A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders.Sanacora G, Frye MA, McDonald W, Mathew SJ, Turner MS, Schatzberg AF, Summergrad P, Nemeroff CB. JAMA Psychiatry. 2017 Apr 1. PMID: 28249076.
Treatment Outcome Comparison Between Telepsychiatry and Face-to-face Buprenorphine Medication-assisted Treatment for Opioid Use Disorder: A 2-Year Retrospective Data Analysis.Zheng W, Nickasch M, Lander L, Wen S, Xiao M, Marshalek P, Dix E, Sullivan C. J Addict Med. 2017 Mar/Apr. PMID: 28107210.
Procedural Consolidation During Electroconvulsive Therapy for a Patient With Severe Tourette Syndrome.Katz R, Bukanova E, Ostroff R. J ECT. 2017 Mar. PMID: 28009622.
A Case of Anesthesia Mumps with Electroconvulsive Therapy.Katz RB, Helgeson L, Ostroff R. J ECT. 2017 Mar. PMID: 27922460.
Adjunctive Lanicemine (AZD6765) in Patients with Major Depressive Disorder and History of Inadequate Response to Antidepressants: A Randomized, Placebo-Controlled Study.Sanacora G, Johnson MR, Khan A, Atkinson SD, Riesenberg RR, Schronen JP, Burke MA, Zajecka JM, Barra L, Su HL, Posener JA, Bui KH, Quirk MC, Piser TM, Mathew SJ, Pathak S. Neuropsychopharmacology. 2017 Mar; 2016 Sep 29. PMID: 27681442.
Computer-Assisted Cognitive Behavior Therapy to Prevent Relapse Following Electroconvulsive Therapy.Wilkinson ST, Ostroff RB, Sanacora G. J ECT. 2017 Mar. PMID: 27564424.
Characterization of GABAergic marker expression in the chronic unpredictable stress model of depression.Banasr M, Lepack A, Fee C, Duric V, Maldonado-Aviles J, DiLeone R, Sibille E, Duman RS, Sanacora G. Chronic Stress (Thousand Oaks). 2017 Feb; 2017 Aug 3. PMID: 28835932.
A Case Suspended in Time: The Educational Value of Case Reports.Packer CD, Katz RB, Iacopetti CL, Krimmel JD, Singh MK. Acad Med. 2017 Feb. PMID: 27097050.
Cognitive Behavior Therapy May Sustain Antidepressant Effects of Intravenous Ketamine in Treatment-Resistant Depression.Wilkinson ST, Wright D, Fasula MK, Fenton L, Griepp M, Ostroff RB, Sanacora G. Psychother Psychosom. 2017; 2017 May 11. PMID: 28490030.
Inflammation, Glutamate, and Glia: A Trio of Trouble in Mood Disorders.Haroon E, Miller AH, Sanacora G. Neuropsychopharmacology. 2017 Jan; 2016 Sep 15. PMID: 27629368.
Neuropsychiatric aspects of concussion.Radhakrishnan R, Garakani A, Gross LS, Goin MK, Pine J, Slaby AE, Sumner CR, Baron DA. Lancet Psychiatry. 2016 Dec. PMID: 27889010.
Anxiety symptoms in survivors of critical illness: a systematic review and meta-analysis.Nikayin S, Rabiee A, Hashem MD, Huang M, Bienvenu OJ, Turnbull AE, Needham DM. Gen Hosp Psychiatry. 2016 Nov-Dec; 2016 Aug 28. PMID: 27796253.
Depressive Symptoms After Critical Illness: A Systematic Review and Meta-Analysis.Rabiee A, Nikayin S, Hashem MD, Huang M, Dinglas VD, Bienvenu OJ, Turnbull AE, Needham DM. Crit Care Med. 2016 Sep. PMID: 27153046.
A Systematic Review of the Evidence for Medical Marijuana in Psychiatric Indications.Wilkinson ST, Radhakrishnan R, D'Souza DC. J Clin Psychiatry. 2016 Aug. PMID: 27561138.
KETAMINE: A POTENTIAL RAPID-ACTING ANTISUICIDAL AGENT?Wilkinson ST, Sanacora G. Depress Anxiety. 2016 Aug; 2016 Apr 15. PMID: 27082101.
KETAMINE'S MECHANISM OF ACTION: A PATH TO RAPID-ACTING ANTIDEPRESSANTS.Abdallah CG, Adams TG, Kelmendi B, Esterlis I, Sanacora G, Krystal JH. Depress Anxiety. 2016 Aug; 2016 Apr 6. PMID: 27062302.
A Double-Blind, Randomized, Placebo-Controlled, Dose-Frequency Study of Intravenous Ketamine in Patients With Treatment-Resistant Depression.Singh JB, Fedgchin M, Daly EJ, De Boer P, Cooper K, Lim P, Pinter C, Murrough JW, Sanacora G, Shelton RC, Kurian B, Winokur A, Fava M, Manji H, Drevets WC, Van Nueten L. Am J Psychiatry. 2016 Aug 1; 2016 Apr 8. PMID: 27056608.
Asian Indians in America: The influence of values and culture on mental health.Chandra RM, Arora L, Mehta UM, Asnaani A, Radhakrishnan R. Asian J Psychiatr. 2016 Aug; 2015 Sep 28. PMID: 26442987.
Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research.Krystal JH, Abi-Dargham A, Akbarian S, Arnsten AFT, Barch DM, Bearden CE, Braff DL, Brown ES, Bullmore ET, Carlezon WA Jr, Carter CS, Cook EH Jr, Daskalakis ZJ, DiLeone RJ, Duman RS, Grace AA, Hariri AR, Harrison PJ, Hiroi N, Kenny PJ, Kleinman JE, Krystal AD, Lewis DA, Lipska BK, Marder SR, Mason GF, Mathalon DH, McClung CA, McDougle CJ, McIntosh AM, McMahon FJ, Mirnics K, Monteggia LM, Narendran R, Nestler EJ, Neumeister A, O'Donovan MC, Öngür D, Pariante CM, Paulus MP, Pearlson G, Phillips ML, Pine DS, Pizzagalli DA, Pletnikov MV, Ragland JD, Rapoport JL, Ressler KJ, Russo SJ, Sanacora G, Sawa A, Schatzberg AF, Shaham Y, Shamay-Tsoory SG, Sklar P, State MW, Stein MB, Strakowski SM, Taylor SF, Turecki G, Turetsky BI, Weissman MM, Zachariou V, Zarate CA Jr, Zubieta JK. Biol Psychiatry. 2016 Jul 15. PMID: 27346079.
What Are We Learning From Early-Phase Clinical Trials With Glutamate Targeting Medications for the Treatment of Major Depressive Disorder.Sanacora G. JAMA Psychiatry. 2016 Jul 1. PMID: 27303925.
Reduced Brain Cannabinoid Receptor Availability in Schizophrenia.Ranganathan M, Cortes-Briones J, Radhakrishnan R, Thurnauer H, Planeta B, Skosnik P, Gao H, Labaree D, Neumeister A, Pittman B, Surti T, Huang Y, Carson RE, D'Souza DC. Biol Psychiatry. 2016 Jun 15; 2015 Aug 29. PMID: 26432420.
Reflections on an Innovation: The First Trainee-Led Academic Psychiatry Journal.Charoensook J, Sidaros R, Pier K, Millard H, Wasser T, Richards M, Radhakrishnan R. Acad Psychiatry. 2016 Jun; 2016 Mar 17. PMID: 26988840.
The American Journal of Psychiatry Residents' Journal: Training the Next Generation of Academic Psychiatrists.Wasser T, Richards M, Radhakrishnan R, Freedman R. Am J Psychiatry. 2016 May 1. PMID: 27133407.
The Use of Ketamine for the Treatment of Depression in the Context of Psychotic Symptoms: To the Editor.da Frota Ribeiro CM, Sanacora G, Hoffman R, Ostroff R. Biol Psychiatry. 2016 May 1; 2015 Jun 4. PMID: 26212896.
Human Laboratory Studies on Cannabinoids and Psychosis.Sherif M, Radhakrishnan R, D'Souza DC, Ranganathan M. Biol Psychiatry. 2016 Apr 1; 2016 Feb 2. PMID: 26970363.
Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants.Duman RS, Aghajanian GK, Sanacora G, Krystal JH. Nat Med. 2016 Mar. PMID: 26937618.
The Formation of Marijuana Risk Perception in a Population of Substance Abusing Patients.Wilkinson ST, van Schalkwyk GI, Davidson L, D'Souza DC. Psychiatr Q. 2016 Mar. PMID: 25982082.
A Meta-analytic Review of Non-specific Effects in Randomized Controlled Trials of Cognitive Remediation for Schizophrenia.Radhakrishnan R, Kiluk BD, Tsai J. Psychiatr Q. 2016 Mar. PMID: 25952944.
Successful Treatment of Tourette Syndrome With Electroconvulsive Therapy: A Case Report.Guo JN, Kothari JS, Leckman JF, Ostroff RB. Biol Psychiatry. 2016 Mar 1; 2014 Oct 5. PMID: 25481620.
Cannabinoids and Psychosis.D'Souza DC, Radhakrishnan R, Sherif M, Cortes-Briones J, Cahill J, Gupta S, Skosnik PD, Ranganathan M. Curr Pharm Des. 2016. PMID: 27568729.
Marijuana Legalization: Impact on Physicians and Public Health.Wilkinson ST, Yarnell S, Radhakrishnan R, Ball SA, D'Souza DC. Annu Rev Med. 2016; 2015 Oct 19. PMID: 26515984.
2015 in Review.Freedman R, Lewis DA, Michels R, Pine DS, Rush AJ, Schultz SK, Tamminga CA, Radhakrishnan R. Am J Psychiatry. 2015 Dec. PMID: 26619771.
A history of early life parental loss or separation is associated with successful cognitive-behavioral therapy in major depressive disorder.Niciu MJ, Abdallah CG, Fenton LR, Fasula MK, Black A, Anderson GM, Sanacora G. J Affect Disord. 2015 Nov 15; 2015 Aug 19. PMID: 26363143.
Marijuana use is associated with worse outcomes in symptom severity and violent behavior in patients with posttraumatic stress disorder.Wilkinson ST, Stefanovics E, Rosenheck RA. J Clin Psychiatry. 2015 Sep. PMID: 26455669.
Riluzole augmentation in treatment-refractory obsessive-compulsive disorder: a pilot randomized placebo-controlled trial.Pittenger C, Bloch MH, Wasylink S, Billingslea E, Simpson R, Jakubovski E, Kelmendi B, Sanacora G, Coric V. J Clin Psychiatry. 2015 Aug. PMID: 26214725.
Psy-feld: An Innovative Didactic Using the TV Show Seinfeld to Teach Delusional Disorder Subtypes.Tobia A, Bisen V, Zimmerman A, Trenton A, Dix E, Dobkin R. Acad Psychiatry. 2015 Aug; 2014 Nov 20. PMID: 25410045.
GABA Deficits Enhance the Psychotomimetic Effects of Δ9-THC.Radhakrishnan R, Skosnik PD, Cortes-Briones J, Sewell RA, Carbuto M, Schnakenberg A, Cahill J, Bois F, Gunduz-Bruce H, Pittman B, Ranganathan M, D'Souza DC. Neuropsychopharmacology. 2015 Jul; 2015 Mar 2. PMID: 25728472.
In vivo ketamine-induced changes in [¹¹C]ABP688 binding to metabotropic glutamate receptor subtype 5.DeLorenzo C, DellaGioia N, Bloch M, Sanacora G, Nabulsi N, Abdallah C, Yang J, Wen R, Mann JJ, Krystal JH, Parsey RV, Carson RE, Esterlis I. Biol Psychiatry. 2015 Feb 1; 2014 Jul 10. PMID: 25156701.
Reversal of non-suppression of cortisol levels in a patient with refractory depression receiving ketamine.Ostroff R, Kothari JS. Am J Psychiatry. 2015 Jan. PMID: 25553498.
Regulation of extrasynaptic glutamate levels as a pathophysiological mechanism in disorders of motivation and addiction.McCullumsmith RE, Sanacora G. Neuropsychopharmacology. 2015 Jan. PMID: 25482181.
Ketamine and rapid-acting antidepressants: a window into a new neurobiology for mood disorder therapeutics.Abdallah CG, Sanacora G, Duman RS, Krystal JH. Annu Rev Med. 2015; 2014 Oct 17. PMID: 25341010.
Glutamate metabolism in major depressive disorder.Abdallah CG, Jiang L, De Feyter HM, Fasula M, Krystal JH, Rothman DL, Mason GF, Sanacora G. Am J Psychiatry. 2014 Dec 1; 2014 Oct 31. PMID: 25073688.
Electroconvulsive therapy and cerebral aneurysms.Wilkinson ST, Helgeson L, Ostroff RB. J ECT. 2014 Dec. PMID: 25010028.
Medicalization of marijuana--reply.Wilkinson ST, D'Souza DC. JAMA. 2014 Nov 12. PMID: 25387198.
Delirium presenting as mania in a patient with end-stage COPD.Wilkinson ST, Chang SB, Foley T, Lipsey JR, MacKinnon DF. Am J Psychiatry. 2014 Aug. PMID: 25082489.
Problems with the medicalization of marijuana.Wilkinson ST, D'Souza DC. JAMA. 2014 Jun 18. PMID: 24845238.
Impact of Cannabis Use on the Development of Psychotic Disorders.Wilkinson ST, Radhakrishnan R, D'Souza DC. Curr Addict Rep. 2014 Jun 1. PMID: 25767748.
Body mass index identified as an independent predictor of psychiatric readmission.Manu P, Khan S, Radhakrishnan R, Russ MJ, Kane JM, Correll CU. J Clin Psychiatry. 2014 Jun. PMID: 25004198.
Gone to Pot - A Review of the Association between Cannabis and Psychosis.Radhakrishnan R, Wilkinson ST, D'Souza DC. Front Psychiatry. 2014; 2014 May 22. PMID: 24904437.
Decreased occipital cortical glutamate levels in response to successful cognitive-behavioral therapy and pharmacotherapy for major depressive disorder.Abdallah CG, Niciu MJ, Fenton LR, Fasula MK, Jiang L, Black A, Rothman DL, Mason GF, Sanacora G. Psychother Psychosom. 2014; 2014 Aug 6. PMID: 25116726.
Glial abnormalities in substance use disorders and depression: does shared glutamatergic dysfunction contribute to comorbidity?Niciu MJ, Henter ID, Sanacora G, Zarate CA Jr. World J Biol Psychiatry. 2014 Jan; 2013 Sep 12. PMID: 24024876.
Lithium toxicity presenting as transient transcortical motor aphasia: a case report.Katz RB, Packer CD. Psychosomatics. 2014 Jan-Feb; 2013 Sep 3. PMID: 24011866.
Thyroid dysfunction in major psychiatric disorders in a hospital based sample.Radhakrishnan R, Calvin S, Singh JK, Thomas B, Srinivasan K. Indian J Med Res. 2013 Dec. PMID: 24521631.
Scopolamine rapidly increases mammalian target of rapamycin complex 1 signaling, synaptogenesis, and antidepressant behavioral responses.Voleti B, Navarria A, Liu RJ, Banasr M, Li N, Terwilliger R, Sanacora G, Eid T, Aghajanian G, Duman RS. Biol Psychiatry. 2013 Nov 15; 2013 Jun 14. PMID: 23751205.
Medical and recreational marijuana: commentary and review of the literature.Wilkinson ST. Mo Med. 2013 Nov-Dec. PMID: 24564006.
Delayed amnesic syndrome after riluzole use in major depressive disorder: a case report.Cardoos A, Inamori A, Sanacora G, Fava M, Mischoulon D. Psychosomatics. 2013 Sep-Oct; 2013 Mar 6. PMID: 23473447.
From pathophysiology to novel antidepressant drugs: glial contributions to the pathology and treatment of mood disorders.Sanacora G, Banasr M. Biol Psychiatry. 2013 Jun 15. PMID: 23726152.
Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond.Krystal JH, Sanacora G, Duman RS. Biol Psychiatry. 2013 Jun 15. PMID: 23726151.
Acute effects of THC on time perception in frequent and infrequent cannabis users.Sewell RA, Schnakenberg A, Elander J, Radhakrishnan R, Williams A, Skosnik PD, Pittman B, Ranganathan M, D'Souza DC. Psychopharmacology (Berl). 2013 Mar; 2012 Nov 24. PMID: 23179965.
Feasibility, safety, and efficacy of the combination of D-serine and computerized cognitive retraining in schizophrenia: an international collaborative pilot study.D'Souza DC, Radhakrishnan R, Perry E, Bhakta S, Singh NM, Yadav R, Abi-Saab D, Pittman B, Chaturvedi SK, Sharma MP, Bell M, Andrade C. Neuropsychopharmacology. 2013 Feb; 2012 Oct 24. PMID: 23093223.
A case of amelioration of venlafaxine-discontinuation "brain shivers" with atomoxetine.Cortes JA, Radhakrishnan R. Prim Care Companion CNS Disord. 2013. PMID: 23930231.
Effects of ketamine in treatment-refractory obsessive-compulsive disorder.Bloch MH, Wasylink S, Landeros-Weisenberger A, Panza KE, Billingslea E, Leckman JF, Krystal JH, Bhagwagar Z, Sanacora G, Pittenger C. Biol Psychiatry. 2012 Dec 1; 2012 Jul 10. PMID: 22784486.
Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients.Laje G, Lally N, Mathews D, Brutsche N, Chemerinski A, Akula N, Kelmendi B, Simen A, McMahon FJ, Sanacora G, Zarate C Jr. Biol Psychiatry. 2012 Dec 1; 2012 Jul 6. PMID: 22771240.
Suicide: An Indian perspective.Radhakrishnan R, Andrade C. Indian J Psychiatry. 2012 Oct. PMID: 23372232.
Naltrexone does not attenuate the effects of intravenous Δ9-tetrahydrocannabinol in healthy humans.Ranganathan M, Carbuto M, Braley G, Elander J, Perry E, Pittman B, Radhakrishnan R, Sewell RA, D'Souza DC. Int J Neuropsychopharmacol. 2012 Oct; 2012 Jan 16. PMID: 22243563.
Rapid antidepressant effect of ketamine in the electroconvulsive therapy setting.Abdallah CG, Fasula M, Kelmendi B, Sanacora G, Ostroff R. J ECT. 2012 Sep. PMID: 22847373.
Perphenazine suspension: a new, old treatment, side effects and continuous use.Chrisphonte P, Ostroff RB, Rosenheck RA. Psychiatr Q. 2012 Sep. PMID: 22271354.
Heart rate variability responses to standing are attenuated in drug naive depressed patients.Pradeep J, Sambashivaiah S, Thomas T, Radhakrishnan R, Vaz M, Srinivasan K. Indian J Physiol Pharmacol. 2012 Jul-Sep. PMID: 23734434.
Cortical GABA levels in primary insomnia.Morgan PT, Pace-Schott EF, Mason GF, Forselius E, Fasula M, Valentine GW, Sanacora G. Sleep. 2012 Jun 1; 2012 Jun 1. PMID: 22654200.
¹H-[¹³C]-nuclear magnetic resonance spectroscopy measures of ketamine's effect on amino acid neurotransmitter metabolism.Chowdhury GM, Behar KL, Cho W, Thomas MA, Rothman DL, Sanacora G. Biol Psychiatry. 2012 Jun 1; 2011 Dec 9. PMID: 22169441.
Comparison of three a-priori models in the prediction of serum lithium concentration.Radhakrishnan R, Kanigere M, Menon J, Calvin S, Srinivasan K. Indian J Pharmacol. 2012 Mar. PMID: 22529482.
Practice of electroconvulsive therapy in a tertiary care hospital in Pakistan.Minhas HM, Ostroff R. J ECT. 2012 Mar. PMID: 21983759.
Overview of glutamatergic neurotransmission in the nervous system.Niciu MJ, Kelmendi B, Sanacora G. Pharmacol Biochem Behav. 2012 Feb; 2011 Aug 26. PMID: 21889952.
Intravenous ethanol infusion decreases human cortical γ-aminobutyric acid and N-acetylaspartate as measured with proton magnetic resonance spectroscopy at 4 tesla.Gomez R, Behar KL, Watzl J, Weinzimer SA, Gulanski B, Sanacora G, Koretski J, Guidone E, Jiang L, Petrakis IL, Pittman B, Krystal JH, Mason GF. Biol Psychiatry. 2012 Feb 1; 2011 Aug 19. PMID: 21855054.
Antidepressant-like properties of oral riluzole and utility of incentive disengagement models of depression in mice.Gourley SL, Espitia JW, Sanacora G, Taylor JR. Psychopharmacology (Berl). 2012 Feb; 2011 Jul 21. PMID: 21779782.
Domains and determinants of quality of life in schizophrenia and systemic lupus erythematosus.Radhakrishnan R, Menon J, Kanigere M, Ashok M, Shobha V, Galgali RB. Indian J Psychol Med. 2012 Jan. PMID: 22661808.
Towards a glutamate hypothesis of depression: an emerging frontier of neuropsychopharmacology for mood disorders.Sanacora G, Treccani G, Popoli M. Neuropharmacology. 2012 Jan; 2011 Aug 3. PMID: 21827775.
Association between unconjugated bilirubin and schizophrenia.Radhakrishnan R, Kanigere M, Menon J, Calvin S, Janish A, Srinivasan K. Psychiatry Res. 2011 Oct 30; 2011 Apr 5. PMID: 21470692.
Prayer, randomized controlled trials and distance healing: A response to Dr. Jana.Andrade C, Radhakrishnan R. Indian J Psychiatry. 2011 Jul. PMID: 22135451.
Association of polymorphisms in HCN4 with mood disorders and obsessive compulsive disorder.Kelmendi B, Holsbach-Beltrame M, McIntosh AM, Hilt L, George ED, Kitchen RR, Carlyle BC, Pittenger C, Coric V, Nolen-Hoeksema S, Sanacora G, Simen AA. Neurosci Lett. 2011 Jun 8; 2011 Apr 20. PMID: 21529705.
Levetiracetam in the management of bipolar depression: a randomized, double-blind, placebo-controlled trial.Saricicek A, Maloney K, Muralidharan A, Ruf B, Blumberg HP, Sanacora G, Lorberg B, Pittman B, Bhagwagar Z. J Clin Psychiatry. 2011 Jun; 2010 Oct 19. PMID: 21034692.
Electroconvulsive treatment performed in the operating room on a depressed patient before surgery.Beltran C, Ostroff R. J ECT. 2011 Mar. PMID: 21336046.
The antidepressant effect of ketamine is not associated with changes in occipital amino acid neurotransmitter content as measured by [(1)H]-MRS.Valentine GW, Mason GF, Gomez R, Fasula M, Watzl J, Pittman B, Krystal JH, Sanacora G. Psychiatry Res. 2011 Feb 28; 2011 Jan 12. PMID: 21232924.
Standard operating procedures for clinical practice.Rao TS, Radhakrishnan R, Andrade C. Indian J Psychiatry. 2011 Jan. PMID: 21430999.
Computerized ambulatory monitoring in mood disorders: feasibility, compliance, and reactivity.Husky MM, Gindre C, Mazure CM, Brebant C, Nolen-Hoeksema S, Sanacora G, Swendsen J. Psychiatry Res. 2010 Jul 30; 2010 May 21. PMID: 20488558.
Prayer, randomized controlled trials and healing: A response to Prof. Abraham Verghese.Andrade C, Radhakrishnan R. Indian J Psychiatry. 2010 Apr. PMID: 20838511.
Cortical inhibition, gamma-aminobutyric acid, and major depression: there is plenty of smoke but is there fire?Sanacora G. Biol Psychiatry. 2010 Mar 1. PMID: 20159143.
Reduced density of calbindin immunoreactive GABAergic neurons in the occipital cortex in major depression: relevance to neuroimaging studies.Maciag D, Hughes J, O'Dwyer G, Pride Y, Stockmeier CA, Sanacora G, Rajkowska G. Biol Psychiatry. 2010 Mar 1; 2009 Dec 9. PMID: 20004363.
The evolution of Indian psychiatric research: An examination of the early decades of the Indian Journal of Psychiatry.Radhakrishnan R, Andrade C. Indian J Psychiatry. 2010 Jan. PMID: 21836678.
Do glutamatergic agents represent a new class of antidepressant drugs? Part 2.Sanacora G. J Clin Psychiatry. 2009 Nov. PMID: 20031105.
Prayer and healing: A medical and scientific perspective on randomized controlled trials.Andrade C, Radhakrishnan R. Indian J Psychiatry. 2009 Oct-Dec. PMID: 20048448.
Do glutamatergic agents represent a new class of antidepressant drugs? Part 1.Sanacora G. J Clin Psychiatry. 2009 Oct. PMID: 19906350.
Targeting glial physiology and glutamate cycling in the treatment of depression.Valentine GW, Sanacora G. Biochem Pharmacol. 2009 Sep 1; 2009 Apr 17. PMID: 19376090.
Neuroplasticity as a target for the pharmacotherapy of anxiety disorders, mood disorders, and schizophrenia.Krystal JH, Tolin DF, Sanacora G, Castner SA, Williams GV, Aikins DE, Hoffman RE, D'Souza DC. Drug Discov Today. 2009 Jul; 2009 May 19. PMID: 19460458.
Safety and efficacy of antipsychotic drugs for the behavioral and psychological symptoms of dementia.Andrade C, Radhakrishnan R. Indian J Psychiatry. 2009 Jan. PMID: 21416025.
The prevention and treatment of cognitive decline and dementia: An overview of recent research on experimental treatments.Andrade C, Radhakrishnan R. Indian J Psychiatry. 2009 Jan. PMID: 19742190.
Reviewing medications for bipolar disorder: understanding the mechanisms of action.Sanacora G. J Clin Psychiatry. 2009 Jan. PMID: 19222977.
Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications.Sen S, Duman R, Sanacora G. Biol Psychiatry. 2008 Sep 15; 2008 Jun 24. PMID: 18571629.
Major depression: emerging therapeutics.Sen S, Sanacora G. Mt Sinai J Med. 2008 May-Jun. PMID: 18704976.
Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders.Sanacora G, Zarate CA, Krystal JH, Manji HK. Nat Rev Drug Discov. 2008 May. PMID: 18425072.
It is time to take a stand for medical research and against terrorism targeting medical scientists.Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, Berman KF, Blair J, Braff DL, Brown ES, Calabrese JR, Carlezon WA Jr, Cook EH Jr, Davidson RJ, Davis M, Desimone R, Drevets WC, Duman RS, Essock SM, Faraone SV, Freedman R, Friston KJ, Gelernter J, Geller B, Gill M, Gould E, Grace AA, Grillon C, Gueorguieva R, Hariri AR, Innis RB, Jones EG, Kleinman JE, Koob GF, Krystal AD, Leibenluft E, Levinson DF, Levitt PR, Lewis DA, Liberzon I, Lipska BK, Marder SR, Markou A, Mason GF, McDougle CJ, McEwen BS, McMahon FJ, Meaney MJ, Meltzer HY, Merikangas KR, Meyer-Lindenberg A, Mirnics K, Monteggia LM, Neumeister A, O'Brien CP, Owen MJ, Pine DS, Rapoport JL, Rauch SL, Robbins TW, Rosenbaum JF, Rosenberg DR, Ross CA, Rush AJ, Sackeim HA, Sanacora G, Schatzberg AF, Shaham Y, Siever LJ, Sunderland T, Tecott LH, Thase ME, Todd RD, Weissman MM, Yehuda R, Yoshikawa T, Young EA, McCandless R. Biol Psychiatry. 2008 Apr 15. PMID: 18371494.
Efficacy of electroconvulsive therapy in the treatment of nondepressed psychiatric illness in elderly patients: a review of the literature.Wilkins KM, Ostroff R, Tampi RR. J Geriatr Psychiatry Neurol. 2008 Mar. PMID: 18287164.
New understanding of mechanisms of action of bipolar medications.Sanacora G. J Clin Psychiatry. 2008. PMID: 19265637.
Olanzapine and acute urinary retention in two geriatric patients.Cohen R, Wilkins KM, Ostroff R, Tampi RR. Am J Geriatr Pharmacother. 2007 Sep. PMID: 17996664.
The use of electroconvulsive therapy in postpartum affective disorders.Forray A, Ostroff RB. J ECT. 2007 Sep. PMID: 17804998.
GABAergic contributions to the pathophysiology of depression and the mechanism of antidepressant action.Sanacora G, Saricicek A. CNS Neurol Disord Drug Targets. 2007 Apr. PMID: 17430150.
The NMDA receptor as a therapeutic target in major depressive disorder.Pittenger C, Sanacora G, Krystal JH. CNS Neurol Disord Drug Targets. 2007 Apr. PMID: 17430148.
Preliminary evidence of riluzole efficacy in antidepressant-treated patients with residual depressive symptoms.Sanacora G, Kendell SF, Levin Y, Simen AA, Fenton LR, Coric V, Krystal JH. Biol Psychiatry. 2007 Mar 15; 2006 Dec 4. PMID: 17141740.
Antidepressant-like effects of ceftriaxone in male C57BL/6J mice.Mineur YS, Picciotto MR, Sanacora G. Biol Psychiatry. 2007 Jan 15; 2006 Jul 24. PMID: 16860779.
Combined use of lamotrigine and electroconvulsive therapy in bipolar depression: a case series.Penland HR, Ostroff RB. J ECT. 2006 Jun. PMID: 16801832.
Elevated cerebrospinal fluid substance p concentrations in posttraumatic stress disorder and major depression.Geracioti TD Jr, Carpenter LL, Owens MJ, Baker DG, Ekhator NN, Horn PS, Strawn JR, Sanacora G, Kinkead B, Price LH, Nemeroff CB. Am J Psychiatry. 2006 Apr. PMID: 16585438.
Cortical gamma-aminobutyric acid concentrations in depressed patients receiving cognitive behavioral therapy.Sanacora G, Fenton LR, Fasula MK, Rothman DL, Levin Y, Krystal JH, Mason GF. Biol Psychiatry. 2006 Feb 1; 2005 Sep 1. PMID: 16139814.
Sex differences in diencephalon serotonin transporter availability in major depression.Staley JK, Sanacora G, Tamagnan G, Maciejewski PK, Malison RT, Berman RM, Vythilingam M, Kugaya A, Baldwin RM, Seibyl JP, Charney D, Innis RB. Biol Psychiatry. 2006 Jan 1; 2005 Sep 1. PMID: 16139815.
Beyond monoamines: glutamatergic function in mood disorders.Kugaya A, Sanacora G. CNS Spectr. 2005 Oct. PMID: 16400244.
Riluzole augmentation in treatment-resistant obsessive-compulsive disorder: an open-label trial.Coric V, Taskiran S, Pittenger C, Wasylink S, Mathalon DH, Valentine G, Saksa J, Wu YT, Gueorguieva R, Sanacora G, Malison RT, Krystal JH. Biol Psychiatry. 2005 Sep 1. PMID: 15993857.
Reversal of symptomatic hyperprolactinemia by aripiprazole.Wahl R, Ostroff R. Am J Psychiatry. 2005 Aug. PMID: 16055781.
Antidepressant effect of ketamine during ECT.Ostroff R, Gonzales M, Sanacora G. Am J Psychiatry. 2005 Jul. PMID: 15994728.
Chronic renal failure, hemodialysis, and electroconvulsive therapy: a case report.Williams S, Ostroff R. J ECT. 2005 Mar. PMID: 15791177.
Sex, GABA, and nicotine: the impact of smoking on cortical GABA levels across the menstrual cycle as measured with proton magnetic resonance spectroscopy.Epperson CN, O'Malley S, Czarkowski KA, Gueorguieva R, Jatlow P, Sanacora G, Rothman DL, Krystal JH, Mason GF. Biol Psychiatry. 2005 Jan 1. PMID: 15607299.
Riluzole augmentation for treatment-resistant depression.Sanacora G, Kendell SF, Fenton L, Coric V, Krystal JH. Am J Psychiatry. 2004 Nov. PMID: 15514421.
Brain serotonin transporter availability predicts treatment response to selective serotonin reuptake inhibitors.Kugaya A, Sanacora G, Staley JK, Malison RT, Bozkurt A, Khan S, Anand A, Van Dyck CH, Baldwin RM, Seibyl JP, Charney D, Innis RB. Biol Psychiatry. 2004 Oct 1. PMID: 15450785.
Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression.Sanacora G, Gueorguieva R, Epperson CN, Wu YT, Appel M, Rothman DL, Krystal JH, Mason GF. Arch Gen Psychiatry. 2004 Jul. PMID: 15237082.
Addition of the alpha2-antagonist yohimbine to fluoxetine: effects on rate of antidepressant response.Sanacora G, Berman RM, Cappiello A, Oren DA, Kugaya A, Liu N, Gueorguieva R, Fasula D, Charney DS. Neuropsychopharmacology. 2004 Jun. PMID: 15010697.
Pindolol augmentation in depressed patients resistant to selective serotonin reuptake inhibitors: a double-blind, randomized, controlled trial.Perry EB, Berman RM, Sanacora G, Anand A, Lynch-Colonese K, Charney DS. J Clin Psychiatry. 2004 Feb. PMID: 15003079.
Mutation screen of the glutamate decarboxylase-67 gene and haplotype association to unipolar depression.Lappalainen J, Sanacora G, Kranzler HR, Malison R, Hibbard ES, Price LH, Krystal J, Gelernter J. Am J Med Genet B Neuropsychiatr Genet. 2004 Jan 1. PMID: 14681921.
Clinical studies implementing glutamate neurotransmission in mood disorders.Sanacora G, Rothman DL, Mason G, Krystal JH. Ann N Y Acad Sci. 2003 Nov. PMID: 14684453.
Cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT.Kugaya A, Sanacora G, Verhoeff NP, Fujita M, Mason GF, Seneca NM, Bozkurt A, Khan SA, Anand A, Degen K, Charney DS, Zoghbi SS, Baldwin RM, Seibyl JP, Innis RB. Biol Psychiatry. 2003 Oct 15. PMID: 14550678.
Targeted prefrontal cortical activation with bifrontal ECT.Blumenfeld H, McNally KA, Ostroff RB, Zubal IG. Psychiatry Res. 2003 Jul 30. PMID: 12928104.
Increased cortical GABA concentrations in depressed patients receiving ECT.Sanacora G, Mason GF, Rothman DL, Hyder F, Ciarcia JJ, Ostroff RB, Berman RM, Krystal JH. Am J Psychiatry. 2003 Mar. PMID: 12611844.
Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors.Sanacora G, Mason GF, Rothman DL, Krystal JH. Am J Psychiatry. 2002 Apr. PMID: 11925309.
Monoamine depletion in unmedicated depressed subjects.Berman RM, Sanacora G, Anand A, Roach LM, Fasula MK, Finkelstein CO, Wachen RM, Oren DA, Heninger GR, Charney DS. Biol Psychiatry. 2002 Mar 15. PMID: 11922881.
Genotype-controlled analysis of plasma dopamine beta-hydroxylase activity in psychotic unipolar major depression.Cubells JF, Price LH, Meyers BS, Anderson GM, Zabetian CP, Alexopoulos GS, Nelson JC, Sanacora G, Kirwin P, Carpenter L, Malison RT, Gelernter J. Biol Psychiatry. 2002 Mar 1. PMID: 11904129.