Marc N Potenza, PhD, MD

Professor of Psychiatry, in the Child Study Center and of Neuroscience; Director, Center of Excellence in Gambling Research; Director, Yale Program for Research on Impulsivity and Impulse Control Disorders; Director, Women and Addictive Disorders, Women's Health Research at Yale

Research Interests

Child Psychiatry; Gambling; Impulse Control Disorders; Neurobiology; Psychiatry; Psychotherapy; Substance-Related Disorders; Psychiatry and Psychology

Research Organizations

Psychiatry: Addictions, Division of | Center for Nicotine and Tobacco Use Research at Yale (CENTURY) | Connecticut Mental Health Center | Human Genetics, Division of | Neuroscience Research Training Program (NRTP) | Psychotherapy Development Center | Specialized Center of Research (SCOR) to Develop Gender-Sensitive Treatment for Tobacco Dependence | Stress & Addiction Clinical Research Program | Substance Abuse Research | Women's Behavioral Health Research, Division of | Yale Program for Research on Impulsivity and Impulse Control Disorders

Interdepartmental Neuroscience Program

Women's Health Research at Yale: WHRY Research Cores: Addictive Behaviors Core

Office of Cooperative Research

Research Summary

My research focuses on how non-substance ("behavioral") addictions are similar to and different from substance addictions. We use brain imaging, genetic, clinical, pharmacological, behavioral and epidemiological approaches to study this topic. We are also interested how individual differences related to impulsivity and gender, for example, influence non-substance and substance addictions.

Specialized Terms: Pathological gambling; Impulse control disorders; Substance abuse; Addiction; Gender differences

Extensive Research Description

Dr. Potenza's research has focused on the neurobiology and treatment of substance and non-substance addictions and other disorders characterized by impaired impulse control, particularly the disorders characterized in DSM-IV as “Impulse Control Disorders Not Elsewhere Classified.” The majority of this work has focused on understanding clinical and neurobiological underpinnings of these disorders, and their co-occurrences with other mental health disorders, in order to advance prevention and treatment strategies. Dr. Potenza's research has applied brain imaging, genetic, epidemiological and clinical trials methodologies to gain knowledge and improve prevention and treatment strategies for addictive disorders. This work has also involved a specific focus on gender and identifying potential intermediary phenotypes, like facets of impulsivity, that may in part explain the high rates of co-occurrence between impulse control disorders and other mental health conditions, and might represent novel targets for prevention and treatment strategies. We have treatment studies for people with gambling problems with or without tobacco smoking. We have brain imaging studies for people with gambling or substance use problems.

Selected Publications

Full List of PubMed Publications

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Contact Info

Marc N Potenza, PhD, MD
Mailing Address
PsychiatryCMHC Room S-104
34 Park St

New Haven, CT 06519