Rand J. Gruen, PhD
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About
Biography
Dr. Gruen practices psychotherapy and works with children, adolescents, adults, and families. He also supervises residents in the Yale University Department of Psychiatry.
Appointments
Education & Training
- Postdoctoral Fellow
- Yale University School of Medicine (1989)
- PhD
- University of California, Berkeley, Psychology (1985)
- MA
- University of California, Berkeley, Psychology (1985)
- BA
- University of California, Berkeley, Psychology (1982)
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Rand J. Gruen's published research.
Publications Timeline
A big-picture view of Rand J. Gruen's research output by year.
Benjamin Bunney, MD
John Elsworth, PhD
16Publications
299Citations
Publications
2005
- Mendelson T; Gruen RJ. Cognitive Therapy and Research. 2005,29: 301-314.Peer-Reviewed Original Research
2004
Amyloid-beta deposition is associated with decreased hippocampal glucose metabolism and spatial memory impairment in APP/PS1 mice.
Sadowski M, Pankiewicz J, Scholtzova H, Ji Y, Quartermain D, Jensen CH, Duff K, Nixon RA, Gruen RJ, Wisniewski T. Amyloid-beta deposition is associated with decreased hippocampal glucose metabolism and spatial memory impairment in APP/PS1 mice. J Neuropathol Exp Neurol 2004, 63: 418-28. PMID: 15198121, DOI: 10.1093/jnen/63.5.418.Peer-Reviewed Original Research
1999
Effects of repeated amphetamine treatment on regional GABAA receptor binding.
Gruen RJ, Stoker S, Friedhoff AJ, Bradberry CW. Effects of repeated amphetamine treatment on regional GABAA receptor binding. Brain Res 1999, 825: 180-2. PMID: 10216185, DOI: 10.1016/s0006-8993(99)01150-6.Peer-Reviewed Original Research
1996
Novelty-associated locomotion: correlation with cortical and sub-cortical GABAA receptor binding.
Gruen RJ, Wenberg K, Selim M, Friedhoff AJ, Bradberry CW. Novelty-associated locomotion: correlation with cortical and sub-cortical GABAA receptor binding. Eur J Pharmacol 1996, 309: 115-20. PMID: 8874129, DOI: 10.1016/0014-2999(96)00332-9.Peer-Reviewed Original Research
1995
Alterations in GABAA receptor binding in the prefrontal cortex following exposure to chronic stress.
Gruen RJ, Wenberg K, Elahi R, Friedhoff AJ. Alterations in GABAA receptor binding in the prefrontal cortex following exposure to chronic stress. Brain Res 1995, 684: 112-4. PMID: 7583199, DOI: 10.1016/0006-8993(95)00441-r.Peer-Reviewed Original Research
1991
Individual differences in behavioral measures: Correlations with nucleus accumbens dopamine measured by microdialysis
Bradberry C, Gruen R, Berridge C, Roth R. Individual differences in behavioral measures: Correlations with nucleus accumbens dopamine measured by microdialysis. Pharmacology Biochemistry And Behavior 1991, 39: 877-882. PMID: 1763106, DOI: 10.1016/0091-3057(91)90047-6.Peer-Reviewed Original ResearchCitationsDo endogenous excitatory amino acids influence striatal dopamine release?
Moghaddam B, Gruen RJ. Do endogenous excitatory amino acids influence striatal dopamine release? Brain Res 1991, 544: 329-30. PMID: 2039947, DOI: 10.1016/0006-8993(91)90074-6.Peer-Reviewed Original Research
1990
Effect ofl-glutamate on the release of striatal dopamine: in vivo dialysis and electrochemical studies
Moghaddam B, Gruen R, Roth R, Bunney B, Adams R. Effect ofl-glutamate on the release of striatal dopamine: in vivo dialysis and electrochemical studies. Brain Research 1990, 518: 55-60. PMID: 1975217, DOI: 10.1016/0006-8993(90)90953-9.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsN-methyl-D-aspartate receptor antagonistVivo voltammetryExtracellular DA concentrationsMM GluDA outflowStriatal dopamineReceptor antagonistExtracellular dopamineRat striatumVivo dialysisMicrodialysis probeLocal applicationBasal levelsExtracellular concentrationPathophysiological conditionsVivo releaseDA concentrationDopamineL-glutamateField potentialsIonic changesSignificant increaseSelective microelectrodesDepressionStriatumPerinatal diazepam exposure: alterations in exploratory behavior and mesolimbic dopamine turnover.
Gruen RJ, Deutch AY, Roth RH. Perinatal diazepam exposure: alterations in exploratory behavior and mesolimbic dopamine turnover. Pharmacol Biochem Behav 1990, 36: 169-75. PMID: 2349259, DOI: 10.1016/0091-3057(90)90144-7.Peer-Reviewed Original ResearchRegionally specific alterations in the low-affinity GABAA receptor following perinatal exposure to diazepam
Gruen R, Elsworth J, Roth R. Regionally specific alterations in the low-affinity GABAA receptor following perinatal exposure to diazepam. Brain Research 1990, 514: 151-154. PMID: 2162709, DOI: 10.1016/0006-8993(90)90449-l.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsLow-affinity GABAA receptorsPerinatal exposureGABAA receptorsAbility of GABAPerinatal periodAdult ratsBenzodiazepine receptorsCingulate cortexLow affinity formDiazepamSpecific alterationsSignificant decreaseReceptorsSignificant reductionExposureAffinity formAlterationsHypothalamusGABARatsCortex
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