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Pain Research, Informatics, Multi-morbidities and Education (PRIME) Center

A VA Health Services Research and Development Center of Innovation (COIN)


To improve our understanding of the complex interactions between pain and associated chronic disease and behavioral health factors and to develop and implement effective interventions that can reduce pain, its negative impacts on emotional and physical functioning, and overall disease burden by employing principles of medical informatics, behavioral science, and health services research, and to improve women Veterans' health.

Focused Areas of Research

With a focus on pain and women’s health research, the strategic goals of the PRIME Center are to: (1) Enact a strategic research agenda to advance scientific knowledge and to have a significant impact on improving care for Veterans with pain and associated chronic conditions; (2) Conduct research to improve women Veterans' health; (3) Foster innovative health services research outside the two focused areas; (4) Establish a strong infrastructure that supports mentoring and career development, including partnered, system-oriented research; and (5) Promote interdisciplinary, cross-institutional collaborations and research networks in priority areas.

Who is Eligible?

Veterans with painful medical conditions, including, but not limited to chronic low back pain, diabetic peripheral neuropathic pain, and pain related to Multiple Sclerosis.

Contact Us

For more information about the Center and our research program, please contact The Center at 203-932-5711, extension 2335.

The PRIME Seminar

The PRIME Center - VA Connecticut Healthcare System
950 Campbell Ave., West Haven, CT 06516
Building 35A, 2nd Floor Conference Room (Room 237)
Mondays at noon

Next meeting: October 2, 12:00 noon
Lori Bastian, MD, MPH
Director, PRIME Center
Section Chief of General Internal Medicine
VA Connecticut Healthcare System
Professor of Internal Medicine, Yale School of Medicine

Upcoming Schedule

April 22, 2019 No Seminar
April 29, 2019 Yetsa A. Tuakli-Wosormu, MD, MPH, IOC Dip., Sp. Med TBD
May 6, 2019 Caitlin Sorenson, PsyD The Theory, Process, and Outcomes of Culturally Adapted Psychotherapy and Psychosocial Interventions
May 13, 2019 Allison Gaffey, PhD Sleep, Cardiovascular Disease and Healthcare Utilization in OEF/OIF/OND Veterans
May 20, 2019 Margaret Bauer, PhD The Roles of Self-Affirmation and Emotional Disclosure in Promoting Adjustment to Chronic Financial Stress: An Experimental Investigation
May 27, 2019 No Seminar Memorial Day
June 3, 2019 John R. Blosnich, PhD Health Equity Research about Transgender Veterans in the Veterans Health Administration: The Potential, Problems, and Promise of Electronic Health Record Data
June 10, 2019 Alexandra Singer, PhD Mindfulness Practice and Perceived Stress: A Secondary Analysis of a Randomized Controlled Trial of Mindfulness-Based Cognitive Therapy for Migraine
June 17, 2019 Brenda Fenton, PhD Headache and TBI
June 24, 2019 Lucy Gu, PhD Exploratory Trials Examining the Feasibility and Cost-Effectiveness of Media Methods for Sample Recruitment


  • PRIME Center Director

    Professor of Internal Medicine (General Medicine); Section Chief of General Internal Medicine VA Connecticut Healthcare System; Director, Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center

  • PRIME Center Associate Director

    C.N.H. Long Professor of Medicine (General Medicine) and Professor of Public Health (Health Policy); Co-Leader, Cancer Microbiology

  • PRIME Center Director of Methodologies and Biostatistics

    Associate Professor of Emergency Medicine; Director, Methods Core, Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center; Director, Research Design Clinic, Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center; Consultant for Observational Studies, Yale Center for Analytical Sciences (YCAS)

Video: Investigator Insights: Automated Mobile Ancillary Care for Substance Abuse Treatment

Brent Moore, PhD, Research Psychologist at the VA Connecticut Healthcare System and Research Scientist in the Yale Department of Psychiatry, discusses the Automatic Mobile Ancillary Care for Substance Abuse Treatment program in a video produced by the U.S. Department of Veterans Affairs. Watch it here