2025
A systematic review of anti-suicidal effects of sedative-hypnotics and cognitive behavioral therapy for insomnia
Valentino K, Teopiz K, Wong S, Le G, Badulescu S, Johnson D, Ho R, Rhee T, Cao B, Rosenblat J, Mansur R, McIntyre R. A systematic review of anti-suicidal effects of sedative-hypnotics and cognitive behavioral therapy for insomnia. CNS Spectrums 2025, 30: e45. PMID: 40452498, DOI: 10.1017/s1092852925000318.Peer-Reviewed Original ResearchMeSH KeywordsCognitive Behavioral TherapyHumansHypnotics and SedativesSleep Initiation and Maintenance DisordersSuicidal IdeationSuicide PreventionConceptsColumbia-Suicide Severity Rating ScaleOrexin receptor antagonistsScale for Suicide IdeationCognitive behavioral therapySuicidal ideationCBT-ISedative-hypnoticsBehavioral therapySuicide completersSuicide attemptsReducing depressive symptom severityEffects of sedative-hypnoticsDepressive symptom severityMeasures of suicidalitySeverity Rating ScaleRisk of suicideSleep-related interventionsAssociated with reduced SIComorbid insomniaSuicidal thoughtsSymptom severityRandomized controlled trialsTreating insomniaRating ScaleSleep interventionsNational Trends in Suicidal Thoughts and Suicide Attempts Among High School Students in the United States
Bommersbach T, Olfson M, Rhee T. National Trends in Suicidal Thoughts and Suicide Attempts Among High School Students in the United States. American Journal Of Psychiatry 2025, 182: 639-659. PMID: 40432341, DOI: 10.1176/appi.ajp.20240706.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentCross-Sectional StudiesFemaleHumansMaleStudentsSuicidal IdeationSuicide, AttemptedUnited StatesConceptsPast-year suicidal thoughtsSuicidal thoughtsHigh school studentsHealth risk behaviorsSuicidal symptomsSuicide attemptsNon-Hispanic whitesSchool studentsBehavioral risksBlack studentsNational trendsHigh school seniorsU.S. high school studentsDepressive symptomsAttempted suicideRisk categoriesEstimate national trendsBiennial cross-sectional surveysMultivariate logistic regressionSuicideYouth Risk Behavior SurveySchool seniorsElevated ratesHealth risk categoriesRisk Behavior SurveyFunctional connectome-based predictive modeling of suicidal ideation
Averill L, Tamman A, Fouda S, Averill C, Nemati S, Ragnhildstveit A, Gosnell S, Akiki T, Salas R, Abdallah C. Functional connectome-based predictive modeling of suicidal ideation. Journal Of Affective Disorders 2025, 387: 119518. PMID: 40441623, DOI: 10.1016/j.jad.2025.119518.Peer-Reviewed Original ResearchConceptsSuicidal ideationAssociated with increased suicidal ideationRecurrent major depressive disorderConnectome-based predictive modelingResting-state functional magnetic resonance imagingMechanisms of suicidal behaviorAssociated with suicidal ideationFunctional magnetic resonance imagingMajor depressive disorderDorsal salience networkIncreased suicidal ideationIncreased network integrationIncreased suicide riskThe Menninger ClinicNetwork integrationReduced network integrationRelative to controlsCentral executiveDepressive disorderDepressive episodeSalience networkNeural alterationsSuicidal behaviorSuicide riskBrain networksThe efficacy of lithium in the treatment of suicidal ideation, behavior and suicide: An updated systematic review and meta-analysis of randomized controlled trials
Wang J, Le G, Wong S, Teopiz K, Kwan A, Rosenblat J, Rhee T, Ho R, Lo H, Goldberg J, Vinberg M, Grande I, Mansur R, Meyer J, McIntyre R. The efficacy of lithium in the treatment of suicidal ideation, behavior and suicide: An updated systematic review and meta-analysis of randomized controlled trials. Journal Of Affective Disorders 2025, 387: 119487. PMID: 40441661, DOI: 10.1016/j.jad.2025.119487.Peer-Reviewed Original ResearchConceptsSuicidal ideationBipolar disorderSuicide attemptsCompleted suicideTreatment of suicidal ideationTreating acute maniaRate of completed suicideAnti-suicidal effectsEfficacy of lithiumAcute maniaDiagnostic heterogeneityBD-I.Randomized controlled trialsTreatment fidelitySuicide measuresLithium effectsSuicideIdeationLithium levelsMethodological limitationsAssociated with nonsignificant reductionsMeta-analysis of randomized controlled trialsControlled trialsFirst-line treatmentMeta-analysisTrajectories of positive symptoms and suicidality in individuals at clinical high risk for psychosis
Deng W, MacNutt C, Addington J, Bearden C, Cadenhead K, Carrión R, Keshavan M, Mathalon D, Perkins D, Stone W, Walker E, Woods S, Cannon T. Trajectories of positive symptoms and suicidality in individuals at clinical high risk for psychosis. Journal Of Affective Disorders 2025, 384: 208-213. PMID: 40334865, DOI: 10.1016/j.jad.2025.05.023.Peer-Reviewed Original ResearchConceptsPositive symptomsClinical high riskSuicidal ideationCHR-PMeasures of suicidal ideationEarly stages of psychosisPersistence of suicidal ideationSeverity of depressive symptomsPositive symptom severityAssessment timepointsCHR-P participantsEmergence of suicidalityStages of psychosisCHR-P populationTargeted suicide prevention strategiesPsychotic disordersEarly psychosisSuicide prevention strategiesDepressive symptomsSymptom severityPsychosisIdeationDelusionsSuicideHallucinationsExamining the Factor Structure of the Acquired Capability for Suicide Scale (ACSS) in a Military Population: Initial Development and Validation of a Four-Factor Version of the ACSS
Thomas K, Hoyt W, Goldberg S, Abbas M, Schultz M, Hiserodt M, Wyman M. Examining the Factor Structure of the Acquired Capability for Suicide Scale (ACSS) in a Military Population: Initial Development and Validation of a Four-Factor Version of the ACSS. Psychological Services 2025, 22: 312-323. PMID: 39636588, PMCID: PMC12011536, DOI: 10.1037/ser0000917.Peer-Reviewed Original ResearchConceptsInterpersonal theory of suicideTheory of suicideFour-factor versionInterpersonal theorySuicide ScaleAcquired CapabilityFactor structureMilitary populationNational Guard service membersReturn from deploymentConfirmatory factor analysisMonths postdeploymentMilitary sampleSuicidal behaviorPreliminary supportPredictive validityPostdeployment dataAssessment pointsSuicideService membersTheory-relevantVeteran populationLife experiencesFour-factorAdequate validityHigh rates of suicidality and parasuicidal behavior in individuals at clinical high-risk for psychosis: Implications for suicide risk assessment and suicide prevention
Trujillo T, Mirzakhanian H, Addington J, Bearden C, Cannon T, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Stone W, Walker E, Woods S, Cadenhead K. High rates of suicidality and parasuicidal behavior in individuals at clinical high-risk for psychosis: Implications for suicide risk assessment and suicide prevention. Schizophrenia Research 2025, 281: 1-9. PMID: 40300257, DOI: 10.1016/j.schres.2025.04.030.Peer-Reviewed Original ResearchConceptsClinical high riskCalgary Depression Scale for SchizophreniaClinical high-risk youthSuicide risk assessmentParasuicidal behaviorSuicidal ideationLife eventsSelf-harmNorth American Prodrome Longitudinal StudyClinical high-risk participantsStructured Assessment of Violence RiskAssessment of Violence RiskClinical high-risk groupHealthy controlsRates of suicidal ideationHistory of self-harmHistory of SILevels of suicidalityStressful life eventsPredictors of SIRates of suicideAssociated with worse symptomsCHR participantsPsychotic conversionDSM diagnosesA cohort study of predictors of short-term nonfatal suicidal and self-harm events among individuals with mental health disorders treated in the emergency department
Marcus S, Cullen S, Schmutte T, Xie M, Liu T, Ungar L, Cardamone N, Williams N, Olfson M. A cohort study of predictors of short-term nonfatal suicidal and self-harm events among individuals with mental health disorders treated in the emergency department. Journal Of Psychiatric Research 2025, 186: 458-468. PMID: 40318538, DOI: 10.1016/j.jpsychires.2025.04.035.Peer-Reviewed Original ResearchConceptsSelf-harm eventsMental health disordersED visitsHealth disordersBulimia nervosaEmergency departmentNonfatal suicideDiagnosis of bulimia nervosaElectronic health record dataSuicidal self-harmEmergency mental healthcareSuicide-related eventsLogistic regressionHealth record dataMental health diagnosesEmergency department visitsMental health problemsVisits of individualsSuicidal symptomsMental healthcareED episodesHealth recordsSelf-harmShort-term riskHealth diagnosisDelineating Empirically Plausible Causal Pathways to Suicidality Among People at Clinical High Risk for Psychosis
Bronstein M, Kummerfeld E, Bearden C, Cornblatt B, Walker E, Woods S, Mathalon D, Perkins D, Cadenhead K, Addington J, Cannon T, Vinogradov S. Delineating Empirically Plausible Causal Pathways to Suicidality Among People at Clinical High Risk for Psychosis. Journal Of Psychopathology And Clinical Science 2025, 134: 239-250. PMID: 39913476, DOI: 10.1037/abn0000969.Peer-Reviewed Original ResearchConceptsClinical high riskNorth American Prodrome Longitudinal StudyClinical high-risk samplesAttenuated psychosis symptomsPathways to suicideSuicide risk reductionPsychosis symptomsCausal pathwaysDepressed moodPsychosisIntervention effortsSelf-deprecationSuicideLongitudinal studyMeasurement time pointsStudy timepointsHigh riskSymptomsInterventionHopelessnessMoodTime pointsDepressionIndividualsDirect causesAssociation between loneliness and suicidality among general populations and persons with depressive and bipolar disorders: A systematic review
Lu A, Chan A, Menon T, Le G, Wong S, Ho R, Lo H, Rhee T, Lim P, Guillen-Burgos H, McIntyre R. Association between loneliness and suicidality among general populations and persons with depressive and bipolar disorders: A systematic review. Journal Of Affective Disorders 2025, 380: 777-801. PMID: 40157511, DOI: 10.1016/j.jad.2025.03.150.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBipolar DisorderDepressive DisorderFemaleHumansLonelinessMaleMiddle AgedSuicidal IdeationSuicideYoung AdultConceptsGeneral population sampleBipolar disorderSystematic reviewPopulation sampleAge groupsHealthy adultsWeb of ScienceOlder adultsUnadjusted modelsDepressive symptomsData extractionDepressive disorderEligibility criteriaModerate positive correlationNIH toolPositive associationLonelinessEvaluate personalitySuicideAdultsClinical diagnosisDisordersQuality assessmentAssociationComprehensive assessmentInterpersonal difficulties and suicidal ideation in young people at clinical high-risk for psychosis and help-seeking clinical controls
Bailey A, Bauer B, Mittal V, Ellman L, Strauss G, Walker E, Powers A, Kenney J, Corlett P, Woods S, Gold J, Schiffman J, Waltz J, Silverstein S. Interpersonal difficulties and suicidal ideation in young people at clinical high-risk for psychosis and help-seeking clinical controls. Psychiatry Research 2025, 348: 116467. PMID: 40184931, PMCID: PMC12051163, DOI: 10.1016/j.psychres.2025.116467.Peer-Reviewed Original ResearchConceptsRates of suicidal ideationPresence of suicidal ideationClinical high riskSuicidal ideationInterpersonal difficultiesMental health concernsInterpersonal traumaExperiences of suicidal ideationHelp-seeking controlsDSM-5 diagnosisSame-age peersDSM-5Interpersonal mechanismsDiagnostic groupsIdeationYoung peoplePsychosisClinical controlCHRPHealth concernHigh riskAssociated with presenceDifficultiesSuicideLogistic regression modelsGambling in Connecticut adolescents: Prevalence, socio-demographic characteristics, trauma exposure, suicidality, and other risk behaviors
Stefanovics E, Zhai Z, Potenza M. Gambling in Connecticut adolescents: Prevalence, socio-demographic characteristics, trauma exposure, suicidality, and other risk behaviors. PLOS ONE 2025, 20: e0290589. PMID: 39908256, PMCID: PMC11798454, DOI: 10.1371/journal.pone.0290589.Peer-Reviewed Original ResearchConceptsSocial supportRisk behaviorsCorrelates of gamblingTraumatic experiencesPoor health outcomesAssociated with traumatic experiencesImplement tailored interventionsReceipt of social supportHealth risk behaviorsConnecticut high school studentsSocio-demographic characteristicsFamily social supportAcademic performanceAssociated with suicideInfluence gambling behaviorPublic health concernTailored interventionsHealth outcomesPast-year gamblingYouth Risk Behavior SurveyPoor academic performanceTrauma exposureRisk Behavior SurveyCurrent prevalenceHigh school studentsResilience and Vulnerability: Suicide-Specific Cognitions in a Nationally Representative Sample of US Military Veterans.
Fischer I, Nichter B, Trachik B, Bryan C, Pietrzak R. Resilience and Vulnerability: Suicide-Specific Cognitions in a Nationally Representative Sample of US Military Veterans. The Primary Care Companion For CNS Disorders 2025, 27 PMID: 39823445, DOI: 10.4088/pcc.24m03821.Peer-Reviewed Original ResearchConceptsSuicide-specific cognitionsNationally representative sampleUS military veteransSuicide riskMilitary veteransActivities of daily livingNational Health and ResilienceSample of US military veteransSuicide Cognitions ScalePrevalence of veteransPositive psychological traitsReduce suicide riskAdverse childhood experiencesDaily livingPsychosocial characteristicsSocial supportVeterans StudyUS veteransSuicidal behaviorSuicidal ideationCognitive scalesRepresentative samplePsychological traitsElevated riskSocial connectednessInsight and suicidality in first-episode psychosis: The mediating role of depression
Tayfur S, Song Z, Li F, Hazan H, Gibbs-Dean T, Purushothaman D, Karmani S, Terashima J, Tek C, Srihari V. Insight and suicidality in first-episode psychosis: The mediating role of depression. Schizophrenia Research 2025, 275: 189-195. PMID: 39754935, DOI: 10.1016/j.schres.2024.12.013.Peer-Reviewed Original ResearchConceptsFirst-episode psychosisPredictors of suicideCoordinated specialty careTreatment of depressionPersistence of depressionEffects of depressionSuicide attemptsMediation analysisPrevent suicideDepressionSuicideImpact suicidePsychosisTargeted interventionsLongitudinal cohort studyEarly treatment stageParticipantsSignificant predictorsImproving clinical outcomesRegression analysisSpecialty careClinical outcomesCohort studyRelationshipMonths
2024
Prevalence of mental health conditions, substance use disorders, suicidal ideation and attempts, and experiences of homelessness among Veterans with criminal-legal involvement: A meta-analysis
Edwards E, Fortuna A, Holliday R, Addison H, Tsai J. Prevalence of mental health conditions, substance use disorders, suicidal ideation and attempts, and experiences of homelessness among Veterans with criminal-legal involvement: A meta-analysis. Clinical Psychology Review 2024, 115: 102533. PMID: 39740354, DOI: 10.1016/j.cpr.2024.102533.Peer-Reviewed Original ResearchConceptsSubstance use disordersCriminal-legal systemHistory of incarcerationExperience of homelessnessMental health conditionsCriminal-legalCommunity supervisionHistory of suicidal ideationSuicidal ideationHistory of homelessnessDrug useVeterans Health AdministrationRates of psychosocial difficultiesVeterans Health Administration settingsRates of alcohol useInvolvement experiencesPrevalence of mental health conditionsMinority groupsNon-VHA settingsCurrent homelessnessHomelessnessSuicidal thoughtsUse disorderHealth conditionsAlcohol useIncidence and antecedents of emergent suicidal ideation and behavior among Veterans with serious mental illness receiving intensive case management
Browne J, Mohamed S. Incidence and antecedents of emergent suicidal ideation and behavior among Veterans with serious mental illness receiving intensive case management. Journal Of Psychiatric Research 2024, 181: 607-613. PMID: 39740616, DOI: 10.1016/j.jpsychires.2024.12.018.Peer-Reviewed Original ResearchConceptsEmergent suicidal ideationSuicidal ideationMental illnessBehavior groupCommunity-based treatment programsAffective disorder diagnosesSix-month follow-up assessmentFollow-up assessmentService useSubjective distressDisorder diagnosisLifetime hospitalizationsQuality of lifeIdeationProgram evaluation dataTreatment programsVeteransVeterans Health AdministrationBaseline quality of lifePrimary study aimSix-month incidenceBehavioral patternsHealth AdministrationIllnessHigh-risk groupModerators and Mediators of Treatments for Suicidal Thoughts and Behaviors: A Review of More Than 50 Years of Randomized Controlled Trials
Goger P, Guo R, Jo S, Cha C, Ribeiro J, Huang X, Fox K. Moderators and Mediators of Treatments for Suicidal Thoughts and Behaviors: A Review of More Than 50 Years of Randomized Controlled Trials. Behavior Therapy 2024, 56: 241-260. PMID: 40010898, DOI: 10.1016/j.beth.2024.10.003.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultHumansPsychosocial InterventionRandomized Controlled Trials as TopicSuicidal IdeationSuicide, AttemptedConceptsTherapeutic allianceSuicidal thoughtsBorderline personality disorder diagnosisPersonality disorder diagnosisHistory of STBMediators of treatmentTreatment randomized controlled trialsAnxiety sensitivityPsychosocial treatmentsComorbid depressionDisorder diagnosisTreatment contactTherapeutic relationshipSuicide treatmentReplication attemptTest moderationNo mediationSuicideSuicide ratesModeratelyControlled trialsAdolescentsRandomized controlled trialsAdultsThoughtsEpisodic future thinking and psychopathology: A focus on depression and suicide risk
Nam R, Lowry N, Lawrence O, Novotny L, Cha C. Episodic future thinking and psychopathology: A focus on depression and suicide risk. Current Opinion In Psychology 2024, 59: 101853. PMID: 39128387, DOI: 10.1016/j.copsyc.2024.101853.Peer-Reviewed Original ResearchConceptsEpisodic future thinkingFuture thinkingAssociated with depressive symptomsSignificant cognitive processesAutobiographical eventsEmotional valenceSuicide riskDepressive symptomsSuicidal thoughtsCognitive processesPsychopathologyDepressionSuicideTemporal associationAnhedoniaSadnessThinkingSymptomsThoughtsYouthPerceived discrimination, mental health help-seeking attitudes, and suicide ideation, planning, and attempts among black young adults
Boyd D, Quinn C, Durkee M, Williams E, Constant A, Washington D, Butler-Barnes S, Ewing A. Perceived discrimination, mental health help-seeking attitudes, and suicide ideation, planning, and attempts among black young adults. BMC Public Health 2024, 24: 2019. PMID: 39075376, PMCID: PMC11285399, DOI: 10.1186/s12889-024-19519-1.Peer-Reviewed Original ResearchConceptsMental health help-seeking attitudesHelp-seeking attitudesBlack young adultsExperiences of discriminationEveryday discriminationMental health help-seeking behaviorYoung adultsHealth help-seeking behaviorSuicidal ideationExperiences of everyday discriminationMental health servicesMental health supportLong-term health consequencesHelp-seeking behaviorSuicide prevention effortsFeelings of isolationSuicidal behaviorImpact of discriminationHealth servicesHealth supportLogistic regression analysisSexual healthPrevention effortsStudy participantsRisk of suicidal behaviorImpact of COVID-19-Induced Academic Stress on Insomnia and Suicidal Ideation among Taiwanese Health Trainees and Junior Doctors
Huang P, Lin C, Huang R, Chen J, Potenza M, Strong C, Wang H, Griffiths M, Chen C, Ko N, Shieh S. Impact of COVID-19-Induced Academic Stress on Insomnia and Suicidal Ideation among Taiwanese Health Trainees and Junior Doctors. Medical Science Monitor 2024, 30: e944932. PMID: 38910318, PMCID: PMC11305106, DOI: 10.12659/msm.944932.Peer-Reviewed Original ResearchConceptsInsomnia Severity IndexPsychological distressAcademic stressHealth traineesClinical trainingAssociated with psychological distressHigh academic stressGood mental healthAssociated with higher levelsAssociated with insomniaReduce academic stressSuicidal ideationPromote good mental healthStructural equation modelingAcademic-related stressSignificant mediatorsDASS-21Stress ScaleInsomniaMental healthSelf-designed questionsClinical confidencePostgraduate-yearDistressEquation modeling
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply