Universal, Restricted, and Infrastructure Research Services

Within the School of Medicine, there are a number of services that make available research resources for both internal and external investigators. Below we have listed these services alphabetically.


A-Z List

  • Services Available: Analysis of hCG, progesterone, estradiol, LH, FSH, and TSH levels
  • Equipment Available for Service: Roche Cobas e411 immunoanalyzer.
  • Supplies from Requester: N/A
  • Cost/Fees: None
  • Home Department, Center, or Program: Obstetrics, Gynecology, & Reproductive Sciences
  • Main Contact: Dr. Seth Guller
  • Available to Non-Yale Customers: Yes
  • ISP number: ISP699
  • Resource focus: 
  • Services Available: Creation of Bioinformatics Reports for Brain Tumors
  • Equipment Available for Service: Instron 8874 Materials Testing System - Equipment run by lab staff only; Machine Shop (FMB 532) - Equipment run by lab staff only
  • Supplies from requester: Bone/tendon/ligament/device specimens; funding to cover costs of parts & labor in manufacturing; custom specimen holders
  • Cost/Fees: None
  • Home Department, Center, or Program: Neurosurgery
  • Main Contact:  Zeynep Erson Omay, PhD
  • Available to non-Yale customers: No
  • ISP number: ISP956
  • Resource focus:
  • Services Available: 4-point bending (bone); compression; tension (tendon/ligament); device testing; fatigue/cyclic loading; in vivo loading (small animals).
  • Equipment Available for Service: Sequencing services provided by "Yale Center for Genome Analysis" (YCGA); Yale High Power Computation Cluster provided by Yale Center for Research Computing. (These services are available to Yale faculty/staff with proper training.)
  • Supplies from requester: N/A
  • Cost/Fees: Yes, contact
  • Home Department, Center, or Program: Orthopedics and Rehabilitation
  • Main Contact: Steven Tommasini
  • Available to non-Yale customers: Yes
  • ISP number: ISP949
  • Resource focus:
  • Services Available: Procurement, collection, storage, annotation, consenting, data collection, basic processing, study coordination, regulatory
  • Equipment Available for Service: -80ºC freezers, -20ºC freezer, centrifuge, snorkel, bench space. (The equipment is not available for faculty or staff use unless they are part of the ISP.)
  • Supplies from requester: N/A
  • Cost/Fees: Yes, contact
  • Home Department, Center, or Program: Obstetrics, Gynecology, & Reproductive Sciences
  • Website: Division of Reproductive Sciences
  • Main Contact: Lauren Perley
  • Available to non-Yale customers: Yes
  • ISP number: ISP955
  • Resource focus:
  • Services Available: Research and Design Clinics, Analytic Clinics, Office Hours, Multi-site Clinical Trials, Data management
  • Equipment Available for Service: N/A
  • Supplies from requester: Data and specific aims for projects
  • Cost/Fees: Only charge for analytics that is not covered by grants. All consultations are free of charge including grant preparation provided they are written into the grant budget.
  • Home Department, Center, or Program: Yale Center for Analytical Sciences
  • Website: Yale Center for Analytical Sciences
  • Main Contact: Alicia Lakomski
  • Available to non-Yale customers: Yes
  • ISP number: ISP852
  • Resource focus:
  • Services Available: Plastic embedding/sectioning; Paraffin embedding/sectioning; Special stains; Histomorphometry; Cryosectioning; Imaging/analysis
  • Equipment Available for Service: Microtomes, Cryostat, Embedding Center, Tissue Processors, Image analysis system, Digital camera. (Equipment for use by laboratory staff only.)
  • Supplies from requester: Fixative, containers
  • Cost/Fees: Yes, contact
  • Home Department, Center, or Program: Orthopedics and Rehabilitation
  • Website: Orthopædic Histology and Histomorphometry Laboratory
  • Main Contact: Mark Horowitz
  • Available to non-Yale customers: Yes
  • ISP number:
  • Resource focus:
  • Services Available: 
  • Confocal microscopy:point scanning (Leica) and spinning disk (Perkin Elmer) microscopes equipped for fixed and live cell imaging
  • Mouse Genotyping and Cell Isolation Core
  • Primary cell isolation and mouse genotyping (Arteriogenesis PPG core)
  • Mouse physiology: in vivo and ex vivo studies of cardiac function, Langerhans hearts, blood pressure and ECG monitoring
  • Microsurgery core: mouse and rat surgery
  • Micro-CT core: in vitro and in vivo micro-CT imaging
  • Mouse breeding core: management of mouse colonies
  • Surgical and imaging core: large animal surgery and imaging (Arteriogenesis PPG core)
  • Zebrafish facility: includes zebrafish housing as well facilities for live fish imaging and microinjections
  • Equipment Available for Service: Dissecting microscope with video display; inhaled anesthesia and mechanical ventilator; micrormanometer catheters, pressure transduction equipment, recording and computer analysis; heart perfusion apparatus. (Equipment is not available for individual use.)
  • Supplies from requester: N/A
  • Cost/Fees: Yes, contact
  • Home Department, Center, or Program: Internal Medicine (Cardiovascular Research Center)
  • Main Contact:  Jasheng ZhagLawrence Young 
  • Available to non-Yale customers: Yes
  • ISP number: ISP916
  • Resource focus:
  • Services Available: Angiographic Core Laboratory, Echocardiographic Core Laboratory, ECG Core Laboratory, DUS Core Laboratory, Clinical Events Committee, Data Safety Monitoring Board, Medical Writing and Literature Review, Protocol Development and Review
  • Equipment Available for Service: N/A
  • Supplies from requester: N/A
  • Cost/Fees: Yes, contact
  • Home Department, Center, or Program: MIMED Cardiology
  • Website: Yale Cardiovascular Research Group
  • Main Contact: Carmen Canales
  • Available to non-Yale customers: Yes
  • ISP number: 
  • Resource focus: 
  • Services Available: Advanced light microscopy, including confocal, multi photon, several types of super-resolution, swept field, and light sheet.
  • Equipment Available for Service: Confocal, multiphoton, several types of super-resolution, light sheet and swept field microscopes.
  • Supplies from requester: Cells or tissues to be examined and expendable microscopy reagents.
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Center for Cellular and Molecular Imaging (CCMI)
  • Website: Confocal Microscopy
  • Main Contact:  Michael Nathanson; Al Mennone
  • Available to non-Yale customers: Yes
  • ISP number: ISP288
  • Resource focus: Imaging 
  • Services Available: X-ray diffraction data collection; Crystallization robots; Nanotransfer robot; Imager robots; Nano-ITC; HPLC-MALS; Incubators.
  • Equipment Available for Service: Rigaku X-ray Generator and Pilatus Detector; TTP Labtech 5 Position Deck Mosquito Crystallization Robot; Art Robbins Gryphon LCP Crystallization Robot; Formulatrix Nanotransfer (NT)-8 Robot; Formulatrix Rock Imager-1 Robot; Formulatix Rock Automated Imager-1000; Nano-ITC; Agilent 1290 HPLC Size Exclusion Chromatography-MALS.
  • Supplies from requester: Customer brings their own research samples and consumables for most services.  Contact Jim Murphy about specific consumables that should be brought with your samples.
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Center for Cellular and Molecular Imaging (CCMI)
  • Website:  Macromolecular X-ray Crystallography
  • Main Contact: Jim Murphy
  • Available to non-Yale customers: Yes
  • ISP number: ISP233
  • Resource focus: Crystallography
  • Services Available: Cell imaging core
  • Equipment Available for Service: Leica SP5UV Confocal Microscope; Leica DMI6000 Epifluorescence Microscope
  • Supplies from requester: Cells or Tissues for analysis
  • Cost/Fees: Yes, contact
  • Home Department, Center, or Program: Yale Stem Cell Center
  • Website: Yale Stem Cell Center
  • Main Contact:  Thomas Ardito
  • Available to non-Yale customers: No
  • ISP number:
  • Resource focus:
  • Services Available: 
  • Capture-single, Capture-4-5 samples, Capture-6 samples, Capture-8-10 samples, Capture-16 samples, Target Capture-24 samples, Epi Capture-single
  • FFPE-extraction & repair MIPs/plate
  • Sample QC/CLIA Overhead
  • gDNA (in-house and TruSeq), RNA Library pre (poly A selection), RNA library prep (smRNA), RNA Library prep (ribosomal depletion), RNA Library prep (low input), RNA Library prep (FFPE), 
  • Analysis Consultation per hour, HiSeq 2500 2x75, HiSeq 2500 1x75, HiSeq 2500 2x150, MiSeq 500 Cycle, HS4000 2x100, NovaSeq S1 2x100, NovaSeq S2 2x100, NovaSeq S2 2x150, NovaSeq S4 2x150
  • Equipment Available for Service: 
  • ILLUMINA NOVASEQ (2)
  • SEQUENCING SYSTEM UPGRADE
  • HISEQ 4000 SEQ SYSTEM (2)
  • MICROPLATE READER
  • FREEZER
  • UPRIGHT FREEZER (4)
  • NIMBLEGEN HYBRIDIZATION SYSTEM
  • SINGLE THRESHOLD ANALYZER
  • ULTRASONICATOR
  • 8PORT ETHERNET LINE-CARD XFP OPT
  • LABCHIP GX SYSTEM
  • CLUSTER STATION C-BOT (4)
  • THERMAL CYCLER CHASSIS
  • LIQUID HANDLING WORKSTATION
  • REAL-TIME PCR SYSTEM
  • BLADE SERVER ENCLOSURE
  • REAL-TIME PCR SYSTEM
  • MISEQ
  • BLADE ENCLOSURE WITH SERVERS
  • TOUCH CYCLER
  • THERMAL CYCLER (2)
  • UNIFIED STORAGE (2)
  • HIGH PERFORMANCE COMPUTING CLUST
  • CBOT CLUSTER GENERATION SYSTEM
  • SEQUENCING SYSTEM (2)
  • MANY: LENOVO HPC STORAGE PER QUOTE
  • MANY: HITACHI NAS 4080
  • MANY: LENOVO HPC COMPUTE NODES P (2)
  • SEQUENCING SYSTEM
  • PREP DNA SIZE SELECTION SYSTEM
  • THERMAL CYCLER
  • BLADE ENCLOSURE WITH SERVERS (2)


  • Services Available: Diisocyanate Antibody Serum Titration
  • Equipment Available for Service: BioRad Model 550 plate microplate reader
  • Supplies from requester: Serum 
  • Cost/Fees: None.
  • Home Department, Center, or Program: Yale Occupational & Environmental Health program (YOEMP)
  • Main Contact: Adam WisnewskiCarrie Redlich
  • Available to non-Yale customers: Yes
  • ISP number: 
  • Resource focus: 
  • Services Available: Live Cell Imaging by Fluorescence Light Microscopy, with particular on TIRFM and Spinning Disk Confocal
  • Equipment Available for Service: Total Internal Reflection Fluorescent Microscopes (3); Spinning Disc Confocal (Yokogawa based) with FRAP; Structured Illumination Microscopy
  • Supplies from requester: Cells grow in suitable imaging chambers/coverslips
  • Cost/Fees: Yes, contact
  • Home Department, Center, or Program: Cell Biology
  • Website: Cell Biology
  • Main Contact: Felix Rivera-Molina and Derek Toomre
  • Available to non-Yale customers: Yes
  • ISP number: ISP920
  • Resource focus: 
  • Services Available: Rates for sequence, only, available through YCGA.  Rates for clinical report writing vary
  • Equipment Available for Service: Illumina Novaseq for exome sequencing; custom bioinformatics pipeline for clinical analysis
  • Supplies from requester: Blood, saliva, or tissue sample as source of DNA.
  • Cost/Fees: No fee schedule.
  • Home Department, Center, or Program: Genetics
  • Website: Yale Center for Genome Analysis
  • Main Contact: For high-throughput sequencing, overall, contact Shrikant Mane or Kaya Bilguvar; For clinical testing for hereditary disease, contact Daniel Dykas or Allison Bailey
  • Available to non-Yale customers: No
  • ISP number:
  • Resource focus:
  • Services Available: PCR molecular testings for solid tumor and lymphoma diagnosis. FISH testing of solid tumors for both diagnostic and therapeutic purposes
  • Equipment Available for Service: N/A
  • Supplies from requester: N/A
  • Cost/Fees: Yes, contact
  • Home Department, Center, or Program: Pathology
  • Website: Pathology
  • Main Contact: Dr. Pei Hui
  • Available to non-Yale customers: No
  • ISP number: ISP445
  • Resource focus:
  • Services Available: Clinical study protocol development, biobanking logistics, EHR data analysis
  • Equipment Available for Service: Centrifuge, freezers, computers, etc (All are available if appropriately trained)
  • Supplies from requester: N/A
  • Cost/Fees: Yes, contact
  • Home Department, Center, or Program: O'Brien Center (Nephrology)
  • Website: Nephrology
  • Main Contact: Francis Perry Wilson
  • Available to non-Yale customers: Yes
  • ISP number:
  • Resource focus:
  • Services Available: Procedural training
  • Equipment Available for Service: Central access task trainer; Ultrasound; CVC kits; Sterile Bundles; Supplies are not available after training
  • Supplies from requester: N/A
  • Cost/Fees: Yes, refer to contacts
  • Home Department, Center, or Program: Yale Center for Medical Simulation
  • Main Contact: James Bonz MD
  • Available to non-Yale customers: No
  • ISP number: ISP938
  • Resource focus:
  • Services Available: Multiparameter cell analysis
  • Equipment Available for Service: CyTOF Helios mass cytometer, CyTOF Imaging mass cytometer
  • Supplies from requester: Samples to be analyzed and any specialized reagents, such as antibodies
  • Cost/Fees: Yes; Contact Shelly Ren or the main contact listed below
  • Home Department, Center, or Program: Internal Medicine
  • Website:  CyTOF Facility
  • Main Contact: Ruth Montgomery
  • Available to non-Yale customers: Yes
  • ISP number: ISP928
  • Resource focus: Cell Analysis
  • Services Available: 
  • BAC modification and mouse line distribution services
  • - selection and confirmation of BACs
  • - design and verification of targeting strategies for BAC modification
  • - performance and validation of the BAC modification procedure (recombineering)
  • - CHEF gel purification of linearized BAC DNA for pronuclear injection
  • - [pronuclear injection performed for a fee in the Yale Transgenic Facility]
  • - developing genotyping assays; founder identification
  • CRISPR genome editing services
  • - design of mouse gene editing strategies
  • - production of mouse gene editing reagents
  • - design of cell line gene editing strategies
  • - production of cell line gene editing reagents
  • - performance of cell line editing procedure, validation and selection of multiple clonal cell lines
  • Model organism cell line and distribution
  • - breeding and genotyping investigator-selected mice with ‘Terminator’ mouse
  • - pharmacologic selection and culture of selected tubule cells
  • - maintain and distribute genetically modified cell lines
  • - maintain and distribute well characterized mouse models and multi-allelic combinations
  • Human Sample Investigation
  • - Targeted Urine Proteomics Assay (TUPA)
  • - Imaging Mass Cytometry (IMC)
  • Equipment Available for Service: N/A
  • Supplies from requester: N/A
  • Cost/Fees: No fee schedule
  • Home Department, Center, or Program: Nephrology
  • Website: Nephrology
  • Main Contact: Hong Vu
  • Available to non-Yale customers: Yes
  • ISP number:
  • Resource focus:
  • Services Available: Dishwashing & Autoclave
  • Equipment Available for Service: Autoclave machines (fully depreciated)
  • Supplies from requester: Glassware for washing
  • Cost/Fees: Yes, please contact
  • Home Department, Center, or Program: Genetics
  • Main Contact: Nicholas Balsamo
  • Available to non-Yale customers: No
  • ISP number: ISP533
  • Resource focus: 
  • Services Available: Assay Processing
  • Equipment Available for Service: Incucyte Imaging
  • Supplies from requester: compounds to be tested
  • Cost/Fees: Yes, refer information on fee schedule
  • Home Department, Center, or Program: Obstetrics, Gynecology, & Reproductive Sciences
  • Website: Division of Reproductive Sciences
  • Main Contact: Paulomi Aldo
  • Available to non-Yale customers: Yes
  • ISP number: ISP958
  • Resource focus:
  • Services Available: Bioplex Analyzer Calibur Cell Analyzer, LSRII and Amnis Cell Analyzers, Operator Assisted Cell Sorting, Self-Sorting on SH800 Stratedigm Cell Analyzer
  • Equipment Available for Service: The analytic cytometers are available for independent use to trained investigators. Only select cell sorters can be independently operated by investigators that have been extensively trained.
  • Supplies from requester: Users should bring their own pipettes and filter mesh to filter samples at the cytometers, as well as any solutions needed to dilute their samples.
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Immunobiology
  • Website: Yale Flow Cytometry
  • Main Contact: Ann Haberman
  • Available to non-Yale customers: Yes
  • ISP number: ISP455
  • Resource focus: Cell Analysis
  • Services Available: Fly food
  • Equipment Available for Service: The fly food kettle and dispenser in BCMM are only available to trained staff
  • Supplies from requester: Plugs for vials and bottles.
  • Cost/Fees: Users are billed for the amount of food they order on a monthly basis through the Genetics business office
  • Home Department, Center, or Program: Genetics
  • Main Contact: Kathleen Ayers
  • Available to non-Yale customers: No
  • ISP number: ISP577
  • Resource focus:
  • Services Available: YSM rate calculation form submitted by David Gillich and Mate Horvath in CMed office. Services include CRISPR/Cas genome editing, transgenic mouse production, ES cell-mediated gene targeting, cryopreservation, mouse strain reanimation and rederivation
  • Equipment Available for Service: Microinjection workstations: use restricted, but possibly available to faculty/staff with extensive training. Cell culture biosafety cabinets, incubators: possibly available, but we've never been asked. Minor equipment/apparatus is available for use by other faculty/staff upon request
  • Supplies from requester: Transgenic/targeting vector plasmids, if the investigator chooses, but they can request that we construct their plasmids. They need to provide ideas and help with planning.
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Comparative Medicine
  • Website: Yale Genome Editing Center
  • Main Contact: Tim Nottoli
  • Available to non-Yale customers: Yes
  • ISP number: 
  • Resource focus: 
  • Services Available: Glass washing, autoclaving, and hazardous waste disposal
  • Equipment Available for Service: (2) dishwashers and (2) autoclaves
  • Supplies from requester: N/A
  • Cost/Fees: Yes, refer to contacts
  • Home Department, Center, or Program: Pharmacology
  • Main Contact: Alex Mazzucco
  • Available to non-Yale customers: No
  • ISP number:
  • Resource focus:
  • Services Available: We provide patient samples for research
  • Equipment Available for Service: N/A
  • Supplies from requester: N/A
  • Cost/Fees: Yes, refer to contacts
  • Home Department, Center, or Program: YCCC
  • Website:  Yale Cooperative Center of Excellence in Hematology (YCCEH)
  • Main Contact: Stephanie Halene
  • Available to non-Yale customers: Yes
  • ISP number:
  • Resource focus:
  • Services Available: Access to Hemavet hematology analyzer
  • Equipment Available for Service: Hemavet hematology analyzer: users must be trained prior to use, and then perform analyses themselves.
  • Supplies from requester: Anticoagulated blood samples in the appropriate tube.
  • Cost/Fees: Yes, contact.
  • Home Department, Center, or Program: Yale Coperative Center of Excellence in Hematology (YCCEH) in the Det of Laboratory Medicine
  • Website: Yale Cooperative Center of Excellence in Hematology (YCCEH)
  • Main Contact: Lin Wang
  • Available to non-Yale customers: Yes
  • ISP number: 
  • Resource focus: 
  • Services Available: High Throughput Sequencing
  • Equipment Available for Service: HiSeq 4000 /no
  • Supplies from requester: DNA, RNA
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Stem Cell Center
  • Website:  Yale Stem Cell Center
  • Main Contact: Mei Zhong
  • Available to non-Yale customers: Yes
  • ISP number:
  • Resource focus:
  • Services Available: iPSC generation, gene editing using cas9/CRISPR technology, karyotyping, teratoma formation
  • Equipment Available for Service: Incubators, PCR hood, PCR machine
  • Supplies from requester: Starting material
  • Cost/Fees: No
  • Home Department, Center, or Program: Cell Biology Department and Yale Stem Cell Center
  • Website:  Yale Stem Cell Center
  • Main Contact: Alison Bonds
  • Available to non-Yale customers: Yes
  • ISP number: ISP299
  • Resource focus:
  • Services Available: Provides well characterized cultures of vascular cells while keeping costs limited by operating as a not-for-profit facility
  • Equipment Available for Service: N/A
  • Supplies from requester: N/A
  • Cost/Fees: Yes, refer to contacts
  • Home Department, Center, or Program: VBT program
  • Website:  Vascular Biology & Therapeutics Program
  • Main Contact: Gwendolyn Davis Arrington; Penny Riggione
  • Available to non-Yale customers: Yes
  • ISP number:
  • Resource focus:
  • Services Available: Image anonymization
  • Equipment Available for Service: PACS
  • Supplies from requester: Computers
  • Cost/Fees: Yes, refer to contacts
  • Home Department, Center, or Program: Radiology
  • Website:  Radiology & Biomedical Imaging
  • Main Contact: Cindy Voghell
  • Available to non-Yale customers: No
  • ISP number: ISP941
  • Resource focus:
  • Services Available: Blood Processing; Flow Cytometry; Cell Sorting; Luminex Assays; Use of instrumentation
  • Equipment Available for Service: 
  • BD FACSAria II - not available
  • BD LSR Fortessa (2) - available once trained
  • Luminex 200 - available once trained
  • Supplies from requester: All reagents required for assays need to be provided by users.  All reagents required to QC instrumentation are provided by the core.
  • Cost/Fees: Yes, refer to contacts
  • Home Department, Center, or Program: Laboratory Medicine
  • Website:  Laboratory Medicine
  • Main Contact: Lesley Devine
  • Available to non-Yale customers: No
  • ISP number:
  • Resource focus:
  • Services Available: Plate processing
  • Equipment Available for Service: Essen Zoom Imaging; PC with Software
  • Supplies from requester: Plates and Cells
  • Cost/Fees: Yes, refer to website
  • Home Department, Center, or Program: Obstetrics, Gynecology, & Reproductive Sciences
  • Website:  Division of Reproductive Sciences
  • Main Contact: Paulomi Aldo
  • Available to non-Yale customers: No
  • ISP number: ISP924
  • Resource focus:
  • Services Available: 2P Imaging, operator assisted or microscope training 2P Imaging, unassisted 2P Imaging, off peak Surgical Preparation - intraabdominal, chest or lymph nodes Surgical Preparation - ear or calvarium Animal Preparation - noninvasive Facility Workstation Usage Image Analysis - training or technician performed
  • Equipment Available for Service: Both the two-photon laser scanning microscope and the image analysis software at the computer workstation are available for independent use after training.
  • Supplies from requester: Only software and hardware are available for use. All other supplies should be brought to the facility.
  • Cost/Fees: Yes, refer to contacts
  • Home Department, Center, or Program: 
  • Website: Imaging
  • Main Contact: Ann Haberman
  • Available to non-Yale customers: Yes
  • ISP number: ISP600
  • Resource focus: Imaging
  • Services Available: Courses in various aspects of translational science
  • Equipment Available for Service: Normal classroom A/V equipment
  • Supplies from requester: N/A
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Yale Center for Clinical Investigation
  • Website:  Investigative Medicine Program
  • Main Contact: Jasmine Glaspy
  • Available to non-Yale customers: Yes
  • ISP number: ISP927
  • Resource focus:
  • Services Available: Live mice imaging-no tech assistance; First time training fee; Live mice imaging-with tech assistance
  • Equipment Available for Service: Bruker In Vivo MXPro; PC with Software
  • Supplies from requester: Mice
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Obstetrics, Gynecology, & Reproductive Sciences
  • Website:  Division of Reproductive Sciences
  • Main Contact: Paulomi Aldo
  • Available to non-Yale customers: No
  • ISP number: ISP919
  • Resource focus:
  • Services Available: Graphic Labor, Poster Printing,Special materials, whole slide scanning, ITS reporting (new)
  • Equipment Available for Service: Epson large format printers, Aperio whole slide imager, copiers, laser printer
  • Supplies from requester: USB drives for file transfer
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Pathology
  • Website:  Pathology
  • Main Contact: Katherine Henderson
  • Available to non-Yale customers: No
  • ISP number:
  • Resource focus:
  • Services Available: Size Exclusion Chromatography /Multi Angle Light Scattering (MALS); Flow Field Fractionation /MALS; FL plate reader; Isothermal Micro Calorimetry (ITC); Surface Plasmon Resonance Biosensor (SPR); Dynamic Light Scattering (DLS); High Performance Liquid Chromatography (HPLC);
  • Equipment Available for Service: 
  • Agilent 1100 HPLC
  • Biacore T100 Biosensor
  • VP-ITC Microcalorimeter
  • DynaPro DLS detector
  • SPECTRAmax GEMINI FL plate reader
  • Supplies from requester: All consumables
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Keck
  • Website:  Biophysical Resource
  • Main Contact: Ewa Folta-Stogniew
  • Available to non-Yale customers: Yes
  • ISP number:
  • Resource focus:
  • Services Available: Premix Tube, Plate Sequencing - 96 well/min 48, 384-Well Sequencing, PCR Purification and Sequencing - 96 Well, PCR Purification and Sequencing - 384 Well, Fragment Analysis, TapeStation Genomic DNA QC, TapeStation RNA QC, Ion Torrent Library Prep, Ion Torrent - 314 Chip, Ion Torrent - 316 Chip, Ion Torrent - 318 Chip, Real Time PCR - Plate Run, Real Time PCR - SNP, Real Time PCR - Post Read Only
  • Equipment Available for Service: 
  • ABI 3730xl Sequencers - DNA Sequencing staff only
  • Ion Torrent PGM - DNA Sequencing staff only
  • ABI 7900HT RT-PCR - available to all faculty/staff, no training required
  • Supplies from requester: For all sequencing and fragment analysis services, they provide some combination of sample and primer.  For the RT-PCR, they provide the plate ready to run and they perform all operation and data analysis independently.
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Keck
  • Website:  DNA Sequencing
  • Main Contact: Amy Blanchard
  • Available to non-Yale customers: Yes
  • ISP number: ISP959
  • Resource focus: Cell Analysis 
  • Services Available: 
  • Sample Prep-Simple
  • Sample Prep-Complex
  • Sample Prep-Trypsin
  • Sample Prep-Custom enzyme
  • Sample Prep-TiO2
  • Sample Prep-Desalt
  • Sample Prep-NanoDrop
  • Sample Prep-Offline LC
  • Sample Prep-AAA
  • Sample Prep-iTRAQ-4plex-label
  • Sample Prep-iTRAQ-8plex-label
  • Sample Prep-TMT-6plex-label
  • HRMS-Exact mass
  • HRMS-Intact Protein mass
  • LCMSMS-Basic Protein ID
  • LCMSMS-Short gradient
  • LCMSMS-Medium gradient
  • LCMSMS-Long gradient
  • Targeted-SM-Sample
  • Targeted-SM-StdCurve
  • Targeted-SM-Optimization
  • Targeted-SM-Data analysis
  • DataAnalysis-Labeled-Profiling
  • DataAnalysis-LFQ-Profiling
  • DataAnalysis-Protein ID
  • DataAnalysis-Database Configuration
  • Consulting
  • Open Access-Usage
  • Equipment Available for Service: 
  • Orbitrap Fusion (Not open access)
  • Q-Exactive Plus (Not open access)
  • Orbitrap Elite (Not open access)
  • 4000 QTRAP (Open access)
  • LTQ Velos (Open access)"
  • Supplies from requester: Solvents, vials, eppendorf tubes, in some cases columns, standards, and samples to be analyzed
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Keck
  • Website: Proteomics
  • Main Contact: TuKiet (Tu) Lam
  • Available to non-Yale customers: Yes
  • ISP number: ISP959
  • Resource focus: Cell Analysis
  • Services Available: 
  • Synthesis Services: 25 nanomole, standard oligos, 65 bases on DR. OLIGO; 100 nanomole, standard oligos, 120 bases on DR. OLIGO; 100 nanomole, standard oligos, 119 bases and/or modified oligos on 394; 200 nanomole on 394; 1.0 micromole on 394; RNA (1.0 micromole) on 394; RNA (100 nanomole) on DR. OLIGO
  • Purification Services: 100 nanomole PAGE purification (surcharge per Oligo); 200 nanomole PAGE purification (surcharge per Oligo); 1.0 umole PAGE purification (surcharge per Oligo); Glen-Pak Purification (surcharge per Oligo); Purified RNA - 2'Deprotection/Purification; HPLC Purification (surcharge per Oligo)
  • Cloning Service: 1.0 micromole on DR. OLIGO, Custom Cloning
  • Equipment Available for Service:
  • Dr. Oligo DNA/RNA Synthesizers (oligo staff only)
  • ABI 394 DNA/RNA Synthesizers (oligo staff only)
  • Perkin-Elmer LabChip GX Micro-fluidic Electrophoresis System (oligo staff only)
  • Beckman PACE/MDQ Capillary Electrophoresis System (oligo staff only)
  • Agilent 1100 HPLC Systems (oligo staff only)
  • BioXP 3200 Genomic Workstation (oligo staff only)
  • Supplies from requester: Linearized vectors
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Keck
  • Website:  Oligo Synthesis Resource
  • Main Contact: Joseph DeLuca
  • Available to non-Yale customers: Yes
  • ISP number: ISP959
  • Resource focus: Cell Analysis
  • Services Available: MR imaging and spectroscopy
  • Equipment Available for Service: 3T Prisma, 3T Prisma, 3T Trio, 4T Bruker, 7T Siemens, 4T Bruker (20cm), 9.4T Bruker, 11.75T Bruker
  • Supplies from requester: N/A
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Radiology and Biomedical Imaging
  • Website:  Magnetic Resonance Research Center
  • Main Contact: Tobb Constable
  • Available to non-Yale customers: Yes
  • ISP number: ISP633
  • Resource focus:
  • Services Available: Ready supply of life science, chemicals and research supplies around the university
  • Equipment Available for Service: N/A
  • Supplies from requester: N/A
  • Cost/Fees: No fee schedule
  • Home Department, Center, or Program: University Research Stores
  • Website:  Research Stockroom
  • Main Contact: Joseph Vellali
  • Available to non-Yale customers: No
  • ISP number:
  • Resource focus:
  • Services Available: 
  • Affy 3'-IVT Express
  • Affy WT (Whole Transcript)
  • Affy WT (Whole Transcript) with Reagents
  • Affy miRNA
  • Affy WT Low Input
  • Affy OncoScan Assay (min 8 samples)
  • Affy CytoScan Assay (min 8 samples)
  • Misc: Sample QC
  • Misc: DNase treatment
  • Ill Infinium Genotyping
  • Ill Methylation EPIC (includes bisulfite conversion)
  • PacBio Library Prep (250bp-3kb)
  • PacBio Library Prep (3kb-20kb)
  • PacBio Sequencing (one Smrt Cell)
  • DNA Extraction-Tissue
  • DNA Extraction-Blood
  • DNA Extraction-FFPE
  • HWM DNA Extraction-Cells
  • RNA Isolation-Tissue
  • RNA Isolation-Blood
  • RNA Isolation-FFPE
  • 10x Single cell RNA-Seq library prep
  • 10x Single cell VDJ library prep
  • 10x Genome/Exome library prep
  • Equipment Available for Service:
  • Array Scanner from Illumina and Affymetrix, not available to faculty/staff
  • 10x Genomic controller, not available to faculty/staff
  • Supplies from requester: Samples
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Molecular Biophysics and Biochemistry
  • Website:  Yale Center for Genome Analysis (YCGA)
  • Main Contact: Guilin Wang
  • Available to non-Yale customers: Yes
  • ISP number:
  • Resource focus:
  • Services Available: microCT analysis of animal bones, with the capacity to resolve structures down to 3.5 microns and provide fine structural images at the level of individual trabecula
  • Equipment Available for Service: ScanCo MicroCT 35 machine, operated by Dr. Ben-Hua Sun. The equipment must be used under Dr. Sun's supervision.
  • Supplies from requester: None.
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Endocrinology
  • Website: Insogna Lab
  • Main Contact: Kathryn Kristofik
  • Available to non-Yale customers: Yes
  • ISP number: 
  • Resource focus: 
  • Services Available: Collection of MNCs via Apheresis
  • Equipment Available for Service: Cobe-Spectra or Amicus Apheresis Machines. They are ONLY available, and operated by, trained Apheresis Nursing Staff or Snyder Research Laboratory Personnel, under Apheresis Nurse supervision.
  • Supplies from requester: None -- save for a normal human volunteer donor
  • Cost/Fees: Yes, contact
  • Home Department, Center, or Program: Laboratory Medicine
  • Main Contact: Edward L. Snyder, MD, FACP
  • Available to non-Yale customers: No
  • ISP number:
  • Resource focus:
  • Services Available: Assay processing-full service; Machine use only; Plate Analysis only
  • Equipment Available for Service: Luminex 100 analyzer, PC (use of equipment is not available to customer)
  • Supplies from requester: Only the samples to be analyzed OR they have the option to provide the kit
  • Cost/Fees: None.
  • Home Department, Center, or Program: Obstetrics, Gynecology, & Reproductive Sciences
  • Website: Division of Reproductive Sciences
  • Main Contact: Paulomi Aldo
  • Available to non-Yale customers: Yes
  • ISP number:
  • Resource focus:
  • Services Available: Consultation; custom tissue collection; perfusion; histology, both routine and custom; necropsy; study design; histopathology interpretation; manuscript preparation; grant preparation - collaborative research activities
  • Equipment Available for Service: Histology lab equipment, Microscope equipment, Microbiology lab equipment
  • Supplies from requester: Tissue or animals to be characterized, any specialized collection media that is needed
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Comparative Medicine
  • Website: Mouse Research Pathology
  • Main Contact:  Gordon TerwilligerCaroline Zeiss
  • Available to non-Yale customers: Yes
  • ISP number: SIRIU1
  • Resource focus: Whole animal services
  • Services Available: Plastic embedding/sectioning, Paraffin embedding/sectioning, Special stains, Histomorphometry, Cryosectioning, Imaging/analysis
  • Equipment Available for Service: Microtomes, Cryostat, Embedding Center, Tissue Processors, Image analysis system, Digital camera Equipment for use by laboratory staff only
  • Supplies from requester: Fixative, containers
  • Cost/Fees: Yes, contact
  • Home Department, Center, or Program: Orthopaedics & Rehabilitation
  • Website: Orthopædic Histology and Histomorphometry Laboratory
  • Main Contact: Dr. Mark Horowitz
  • Available to non-Yale customers: Yes
  • ISP number: 
  • Resource focus: 
  • Services Available: Tissue procurement, distribution and analysis
  • Equipment Available for Service: Tissue cutters and stainers, processors and imaging machines - available for use only by facility staff
  • Supplies from requester: They can provide information, case lists or tissue specimens, blocks or slides
  • Cost/Fees: Yes, contact
  • Home Department, Center, or Program: Pathology
  • Website: Pathology
  • Main Contact: David Rimm
  • Available to non-Yale customers: Yes
  • ISP number: ISP433
  • Resource focus: 
  • Services Available: Delivery of fresh blood from healthy adult volunteers
  • Equipment Available for Service: N/A
  • Supplies from requester: Blood must be processed by users
  • Cost/Fees: Yes, contact
  • Home Department, Center, or Program: Laboratory Medicine
  • Website:  Clinical Research at Yale
  • Main Contact: Stephanie Eisenbarth
  • Available to non-Yale customers: Yes
  • ISP number: ISP940
  • Resource focus:
  • Services Available: Scan; Synthesis; Metabolites; Extra Hour - human/large animal; Rodent/small animal imaging hourly rate; NHP use; Preclinical data analysis; Ligand development; PK study
  • Equipment Available for Service: 
  • 1 GE PETtrace Cyclotron
  • 1 Whole body PET/CT scanner (Siemens mCT-X)
  • 1 Whole bode PET-only scanner (Siemens HR+)
  • 1 Brain-dedicated PET scanner (Siemens HRRT)
  • 2 Small Animal scanners (Siemens Focus 220)
  • 1 Small animal PET-CT scanner (Siemens Inveon)
  • Supplies from requester: Customers must provide the humans or animals that are to be scanned
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Radiology & Biomedical Imaging
  • Website:  Yale Positron Emission Tomography
  • Main Contact: Richard E. Carson
  • Available to non-Yale customers: Yes
  • ISP number: ISP500
  • Resource focus: Imaging
  • Services Available: Hiring, reappointing, and terminating postdoctoral and postgraduate trainees
  • Equipment Available for Service: N/A
  • Supplies from requester: N/A
  • Cost/Fees: None.
  • Home Department, Center, or Program: Office for Postdoctoral Affairs
  • Website:  Office for Postdoctoral Affairs
  • Main Contact: John Alvaro
  • Available to non-Yale customers: No
  • ISP number: ISP797
  • Resource focus:
  • Services Available: Processing and sectioning of tissue for Light and EM
  • Equipment Available for Service: Cryostat, Microtomes are available for a fee for service
  • Supplies from requester: All supplies related to use
  • Cost/Fees: None.
  • Home Department, Center, or Program: C&M Physiology Microscopy Core
  • Main Contact: SueAnn Mentone
  • Available to non-Yale customers: No
  • ISP number: 
  • Resource focus: 
  • Services Available: 
  • Obtaining hospital IRB approvals and re-approvals
  • Overall study management
  • Identifying newly diagnosed cancer cases with specific tumors 
  • Requesting and abstracting medical records
  • Obtaining physician consent to contact patients
  • Consenting patients for study participation (English and Spanish) and conducting study interviews
  • Identifying, requesting, and obtaining pathology specimens from pathology departments. 
  • Serving as an honest broker, if necessary for studies that require investigators to remain blinded to the identity of patients
  • Identifying, requesting, and obtaining radiology films/scans
  • Survey administration and cohort follow-up 
  • Equipment Available for Service: N/A
  • Supplies from requester: N/A
  • Cost/Fees: None.
  • Home Department, Center, or Program: Yale Cancer Center
  • Website: Yale Cancer Center
  • Main Contact: Rajni Mehta
  • Available to non-Yale customers: Yes
  • ISP number: 
  • Resource focus: 
  • Services Available: Tissue Harvest Processed for Electron Microscopy; Tissue Harvest that Undergoes Immunocytochemistry followed by Processing for Electron Microscropy; Fixed Tissue Processed for Electron Microscopy; Fixed Tissue that Undergoes Immunocytochemistry followed by Processing for Electron Microscropy
  • Equipment Available for Service: Electron microscope, Tecnai 12 Biotwin; it is not available to trained staff.  There is a dedicated electron microscopist.
  • Supplies from requester: None; supplies are included in the ISP rate calculations
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Comparative Medicine
  • Website:  Comparative Medicine
  • Main Contact: Marya Shanabrough
  • Available to non-Yale customers: Yes
  • ISP number:
  • Resource focus:
  • Services Available: Irradiation machines for irradiations of molecular compounds, cell cultures, animal and human tumor cells, and whole animal experiments
  • Equipment Available for Service: There are four XRAD 320kv x-ray machines along with two Siemans 250kv x-ray machines. There is Cs-137 gamma irradiator.  All equipment is available to faculty/staff after following the training requirements and protocols.
  • Supplies from requester: Users just have to bring their samples to be irradiated in a sealed container (test tube, flask, petri dish)  Animals must be irradiated in an approved mouse/rat pie cage.
  • Cost/Fees: Yes, contact
  • Home Department, Center, or Program: Therapeutic Radiology
  • Main Contact: Paul J Bongiorni
  • Available to non-Yale customers: Yes
  • ISP number:
  • Resource focus:
  • Services Available: Sample processing and short-term storage
  • Equipment Available for Service: Routine lab equiptment. Not available; Limited liquid nitrogen storage space - potentially available.
  • Supplies from requester: N/A
  • Cost/Fees: None.
  • Home Department, Center, or Program: YCCC
  • Main Contact:  Stephanie HaleneTalia MitchellRocco Carbone
  • Available to non-Yale customers: No
  • ISP number: ISP808
  • Resource focus:
  • Services Available: REDCap
  • Equipment Available for Service: This is a web tool for data management. As such the service is provided through a web browser.
  • Supplies from requester: Any internet-enabled device.
  • Cost/Fees: Yes, contact
  • Home Department, Center, or Program: REDCap@Yale
  • Website:  REDCap@Yale
  • Main Contact: RedCap Committee (inquiries will be handled by the REDCap Committee rather than a single person)
  • Available to non-Yale customers: No
  • ISP number:
  • Resource focus:
  • Services Available: Immunofluorescence tests, Imunofluorescense slides, PCR tests, RT-PCR tests
  • Equipment Available for Service: Autoclave, Biosafety hoods, Centrifuges, PCR machines, Fluorescence microscope, CO2 incubators 
  • Supplies from requester: N/A
  • Cost/Fees: Yes, refer to website
  • Home Department, Center, or Program:  Comparative Medicine
  • Website: Mouse
  • Main Contact: Susan Compton
  • Available to non-Yale customers: Yes
  • ISP number:
  • Resource focus:
  • Services Available: 
  • Circular Dichroism- Chirascan
  • Circular Dichroism- Training
  • Spectrofluorometer- PTI-QuantaMaster
  • Spectrofluorometer- Training
  • Stop Flow Spectrofluorometer- Applied Photophysics
  • Stop Flow Spectrofluorometer- Training
  • Equipment Available for Service: Chirascan: Circular Dichroism Spectrometer from Applied Photophysics; Stop Flow Spectrophotometer from Applied Photophysics; PTI-QuantaMaster Fluorometer (All are available to faculty/staff once they are trained.)
  • Supplies from requester: Compressed air tank, liquid nitrogen tank, pipette tips, Kim wipes, acetone, and ethanol
  • Cost/Fees: Yes, refer to information on fee schedule
  • Home Department, Center, or Program: Therapeutic Radiology, Biophysics Keck facility
  • Website:  Biophysical Resource
  • Main Contact: Khadijeh Alnajjar
  • Available to non-Yale customers: Yes
  • ISP number:
  • Resource focus:
  • Services Available: Reproductive tissue procurement and storage
  • Equipment Available for Service: Freezer
  • Supplies from requester: N/A
  • Cost/Fees: Yes, contact
  • Home Department, Center, or Program: Obstetrics, Gynecology & Reproductive Sciences
  • Main Contact: Lauren Perley
  • Available to non-Yale customers: Yes
  • ISP number: 
  • Resource focus: 
  • Services Available: Tissue Clearing and Imaging Service
  • Equipment Available for Service: Clearing reagents, dyes, and custom Multiphoton microscope. Not available for faculty or staff.
  • Supplies from requester: Specimens for imaging. If antibody staining to be imaged, stains must be performed by submitting group. Guidance is available for antibody staining. Data drives may be supplied by ISP at or near cost of desired. (Discussion of experimental plan before specimen submission typically required.)
  • Cost/Fees: Yes, contact
  • Home Department, Center, or Program: Laboratory Medicine
  • Main Contact: Richard Torres, MD
  • Available to non-Yale customers: No
  • ISP number: 
  • Resource focus: 
  • Services Available: Large Animal Echocardiography, Small Animal SPECT/CT, Small Animal Echocardiography, Interventional Imaging Suite, Specimen MicroCT, Hybrid CZT SPECT 64-slice CT, Technologist Assistance, Technologist Assistance Weekends
  • Equipment Available for Service: Equipment is fully operated by core staff.
  • Supplies from requester: Users may need to provide special use catheters and imaging probes.
  • Cost/Fees: Yes, please contact
  • Home Department, Center, or Program: Cardiovascular Medicine
  • Website: Yale Translational Research Imaging Center (Y-TRIC)
  • Main Contact: Donna McMahon
  • Available to non-Yale customers: Yes
  • ISP number: 
  • Resource focus: 
  • Services Available: Fish feeding, monitoring and support of fish health, tank cleaning, zebrafish breeding support, zebrafish in-vitro fertilization, embryo sorting, euthanization of old fish, microscope services
  • Equipment Available for Service: Leica microscopes (stereomicroscopes x3, fluorescence microscopes), embryo injecting equipment, zebrafish housing system (Pentair). Microscopes and injecting equipment are available to faculty/staff once they are trained.
  • Supplies from requester: Anything outside of items related to zebrafish husbandry (i.e. materials associated with genotyping, embryo injection materials, etc.)
  • Cost/Fees: Customers are invoiced for husbandry services
  • Home Department, Center, or Program: Internal Medicine
  • Main Contact: Stefania Nicoli (PI) or Meredith Cavanaugh
  • Available to non-Yale customers: No
  • ISP number: ISP943
  • Resource focus: Fish Experiments

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