Yale Center for Clinical Investigation

About YCCI

In 2004, more than a year before the National Institute of Health (NIH) Clinical and Translational Science Award (CTSA) was announced, Robert J. Alpern, Dean and Ensign Professor of Medicine for the Yale School of Medicine, initiated a strategic planning process to evaluate and further the status of clinical and translational research at the Yale School of Medicine. Two major goals that emerged from the strategic planning process were to expand and centralize the training of the next generation of clinical and translational scientists and to provide a robust infrastructure that would promote innovative and collaborative research directed at improving patient care.

Clinicaltrials.gov Training

Smith & Krystal

From the Co-Directors

Welcome to the website for the Yale Center for Clinical Investigation. 
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Mentor Training for Fall 2019

YCCI is offering mentor training for the Fall of 2019.  If you are interested in participating you would need to commit to attend at least three of the five sessions offered.  The sessions are open to faculty members of any rank who serve as a research mentor.  For more information on mentor training click here.

Pilot Grants 2019

The Yale Center for Clinical Investigation (YCCI) is pleased to announce the 2019 round of pilot grants.  YCCI’s pilot program is a funding venue for conducting small-scale research projects to generate data that potentially could lead to further research and funding opportunities. To learn more visit the website

Full applications are due May 17, 2019 at 5:00 PM

YCCI Scholar Awards 2019 applications are open

We are pleased to announce a request for applications for YCCI Scholar Awards, which provide salary and/or research funds to a select number of junior faculty members who are strongly committed to careers in clinical research, community-based research or translational research.

A letter of intent is required and is due by 5:00 PM on April 12, 2019 and the due date for full applications is May 17, 2019 at 5:00 PM. Click here for more information and links for submission.


Request for applications for the Fund to Retain Clinical Scientists at the Yale School of Medicine (FRCS)

The goal of this exceptional program is to retain early-career physician-scientists in research. The FRCS Program provides research funds to select junior physician-scientists who have a compelling need for additional resources in order to maintain research productivity in the face of extraordinary caregiving needs. Applicants may request up to $50,000 for a one-year award period.

The due date for full applications is May 13, 2019 by 5:00 pm. Click here for more information and links for submission.

Foundations of Community-Engaged Research Course

Under the auspices of the Yale Center for Clinical Investigation (YCCI), the Center for Research Engagement (CRE) and the Yale National Clinician Scholars Program (NCSP) offer post-doctoral training in community partnered research for Yale investigators affiliated with the Schools of Medicine, Public Health, and Nursing. Those who are accepted into the training will be known as YCCI Advanced Health Sciences Fellows. 2019-20 will be the 10th year of our partnered training. Responses due May 20, 2019.

See the Foundations of Community-Engaged Research Course page for details.

Participate in clinical research at Yale

Interested in participating at clinical research at Yale? Search for trials, read patient stories and create a profile and sign up on our website.

Opting Out of Research

There are three ways to opt out of clinical research at Yale. Learn more.

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