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Machine Learning, Data Topology, and Biomedical Datasets – The Krishnaswamy Lab

July 21, 2026

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Research at a Glance

Annals of Surgical Oncology | June 2026
Peritoneal Metastases Evade Circulating Tumor DNA Detection
This study investigates the limitations of circulating tumor DNA (ctDNA) surveillance in stage II–III colon cancer, showing reduced detection of isolated peritoneal metastases due to biological constraints.
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Scientific Reports | February 2026
Gene Programs Behind Lipid Droplet Zonal Distribution in Fatty Liver Disease
This study investigates the genetic and molecular mechanisms behind lipid droplet accumulation in alcohol-related liver disease, revealing zone-specific gene regulation linked to disease progression and therapeutic targets.
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Journal of Political Economy | January 2026
Multigenerational Effects of Early-Life Advantage in Monkeys
This study investigates how early-life advantages in rhesus monkeys influence health and social status across generations, showing benefits persist only for offspring of maternally-reared mothers.
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YSM In the News

The Fundamentals

Yale Medicine Magazine was originally established in the 1950s as the medical school's alumni bulletin. Its articles cover discoveries in biomedicine, clinical advances, new ways of training tomorrow’s doctors, and the evolution of medicine and healthcare.

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Women’s Health Research at Yale Funds Projects on Obesity and Ovarian Aging, Diabetes, Cancers, and Autoimmunity

Beyond BMI: Men and Postmenopausal Women Fare Differently After Bariatric Surgery

YSM Joins International Team to Develop AI for Precision Medicine

How Autistic Brains Process Faces Differently

What the Brain Is Doing When We’re Unaware of Our Actions

Machine Learning, Data Topology, and Biomedical Datasets – The Krishnaswamy Lab

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Motherhood, Restlessness, and SpaceX: Stories of Yale Internal Medicine

When the Science of Casting Becomes Art

MHS Degree Program Welcomes Class of 2028

Inci Yildirim Named the John F. Enders Professor of Pediatrics

Research at a Glance

3D Tumour Atlases Revolutionize Cancer Detection & Treatment

Peritoneal Metastases Evade Circulating Tumor DNA Detection

Gene Programs Behind Lipid Droplet Zonal Distribution in Fatty Liver Disease

Multigenerational Effects of Early-Life Advantage in Monkeys

YSM In the News

What Are the Key Signs of UV Damage to Look For? With Kathleen Suozzi, MD

How fast you should expect symptom relief after HoLEP surgery

Terrifying truth about rapid rise in autoimmune diseases: Scientists make terrifying discovery... and warn of lethal combo of common lifestyle habits

The Fundamentals

In this issue

Scientists Look to Sperm to Improve Reproductive Health and Beyond

Identifying Drug Targets—And Then the Drugs

Events

Yale Cytoskeleton Club Seminar: "Revealing the role of tubulin isotypes in regulating microtubule mechanosensitivity and luminal accessibility"

Yale Child Study Center Developmental Science Internship Symposium

Addiction Medicine Grand Rounds: "Door-to-Balloon Time for Withdrawal: Evidence & New Approaches for Acute Withdrawal in a Fentanyl Era"

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News

Top Stories

Women’s Health Research at Yale Funds Projects on Obesity and Ovarian Aging, Diabetes, Cancers, and Autoimmunity

Beyond BMI: Men and Postmenopausal Women Fare Differently After Bariatric Surgery

YSM Joins International Team to Develop AI for Precision Medicine

How Autistic Brains Process Faces Differently

What the Brain Is Doing When We’re Unaware of Our Actions

Machine Learning, Data Topology, and Biomedical Datasets – The Krishnaswamy Lab

Latest

Motherhood, Restlessness, and SpaceX: Stories of Yale Internal Medicine

When the Science of Casting Becomes Art

MHS Degree Program Welcomes Class of 2028

Inci Yildirim Named the John F. Enders Professor of Pediatrics

Most Read

How to Reverse Insulin Resistance

Can Type 2 Diabetes Be Reversed?

A Two-Pronged Vaccine Approach to Prevent Genital Herpes

Why the FDA Recalled Six Popular Acne Products

Behind the Smoke: Unmasking the Link Between Cannabis and Schizophrenia

Research at a Glance

3D Tumour Atlases Revolutionize Cancer Detection & Treatment

Peritoneal Metastases Evade Circulating Tumor DNA Detection

Gene Programs Behind Lipid Droplet Zonal Distribution in Fatty Liver Disease

Multigenerational Effects of Early-Life Advantage in Monkeys

YSM In the News

What Are the Key Signs of UV Damage to Look For? With Kathleen Suozzi, MD

How fast you should expect symptom relief after HoLEP surgery

Terrifying truth about rapid rise in autoimmune diseases: Scientists make terrifying discovery... and warn of lethal combo of common lifestyle habits

The Fundamentals

In this issue

Scientists Look to Sperm to Improve Reproductive Health and Beyond

Identifying Drug Targets—And Then the Drugs

Events

Yale Cytoskeleton Club Seminar: "Revealing the role of tubulin isotypes in regulating microtubule mechanosensitivity and luminal accessibility"

Yale Child Study Center Developmental Science Internship Symposium

Addiction Medicine Grand Rounds: "Door-to-Balloon Time for Withdrawal: Evidence & New Approaches for Acute Withdrawal in a Fentanyl Era"

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Follow Us on Social Media