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Yale Genome Editing Center

Services and Resources for Creating Genetically Engineered Mice

Pronuclear microinjection of transgene constructs to create transgenic mouse lines.
Creation of genetically altered ES cell lines by homologous recombination. Karyotyping. Generation of chimeric mice by injection of ES cells into blastocysts; transmission of the targeted gene through the germline.
Freezing and storage of mouse embryos.
Call to discuss other embryonic stem cell and mouse embryology-related services.

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