Yale Genome Editing Center

Services and Resources for Creating Genetically Engineered Mice

CRISPR/Cas Genome Editing

Creation of targeted mouse lines via CRISPR/Cas.

Transgenic Mouse Service

Pronuclear microinjection of transgene constructs to create transgenic mouse lines.

The Gene Targeting Service

Creation of genetically altered ES cell lines by homologous recombination. Karyotyping. Generation of chimeric mice by injection of ES cells into blastocysts; transmission of the targeted gene through the germline.

Mouse Embryo Cryopreservation

Freezing and storage of mouse embryos.

Custom Services

Call to discuss other embryonic stem cell and mouse embryology-related services.

Contact Us

Timothy Nottoli, PhD
(203) 737-4325

Xiaojun Xing, MSĀ 
(203) 785-3666