My laboratory investigates vector-borne diseases, including illnesses transmitted by ticks and mosquitoes. Studies are directed toward understanding Lyme disease, human granulocytic ehrlichiosis, flaviviruses and malaria. Efforts on Lyme disease include exploring immunity to Borrelia burgdorferi, and the immunobiology of Lyme arthritis. We are investigating the molecular strategies that Anaplasma phagocytophilum uses to survive in polymorphonuclear leukocytes or ticks. Finally, we are also developing molecular approaches to prevent ticks or mosquitoes from feeding on a mammalian host, thereby interfering with pathogen transmission.
Specialized Terms: Vector-borne diseases; Ticks; Mosquitoes; Lyme disease; Human granulocytic ehrilichiosis; West Nile virus; malaria
Bacteria; Epidemiology; Lyme Disease; Parasitology; Public Health; Ticks; Viruses; West Nile virus; Global Health; Ehrlichiosis; Malaria Vaccines; Borrelia burgdorferi; Infectious Disease Medicine
Infectious Diseases; Mosquito-borne Diseases; Tick-borne Diseases