Joseph Craft, MD
Research & Publications
Biography
News
Research Summary
Dr. Craft investigates CD4 T helper cells in conventional and autoimmune responses in mice and in humans, focusing upon differentiation and function of follicular helper T (Tfh) cells that promote B cell maturation. Tfh-cell dependent GC responses are critical for development of humoral immunity upon vaccine administration or infection, and for driving pathogenic autoreactive B cell responses in autoimmunity. Dr. Craft’s studies on Tfh cells build upon his earlier work in characterizing immune targets in lupus, and studies of tolerance, inflammation, and therapy. His lab also investigates other CD4 T cell populations, including those that promote immune memory and inflammation. Studies by individuals in his lab include those by graduate student Amanda Poholek, in collaboration with Shane Crotty and colleagues, demonstrated that the transcription factor Bcl6 is necessary and sufficient for Tfh-cell genesis. Upon activation, CD4 T cells exhibit metabolic changes to meet their proliferative and effector needs, with the understanding of how metabolism is regulated in T helper (Th) 1 and Tfh cells incomplete. Work by grad students John Ray and Justin Shyer, with Matt Staron in Sue Kaech’s lab, was the first to decipher metabolic events that dictate Tfh-cell vs. Th1 cell development. Shyer and postdoctoral fellow Will Bailis in the Flavell lab at Yale subsequently used a CRISPR/Cas9 screen in primary T cells to reveal metabolic requirements for Th cell proliferation and effector function, a tool that will further aid identification of metabolic pathways needed for Tfh vs. Th1 differentiation. More recent work done by Can Cui, a student in the lab co-mentored by Nik Joshi, has shown a unique role to Tfh-B cell interactions in promoting effector CD8 T cell responses in a tumor model. Ping-Min Chen, a graduate student, demonstrated that upon renal infiltration, T cells adapt to their environment to ensure survival and effector capability, with remodeling of metabolic and epigenetic pathways with tissue damage driven by a hypoxia-dependent inflammatory gene program, which can be therapeutically blocked in lupus models with reversal of tissue damage.
Specialized Terms: T cell development, T cell differentiation and function, autoimmunity; lupus; tolerance
Extensive Research Description
Ongoing studies are targeted towards identification of the developmental pathways of CD4 T cells that provide B cell help and that promote inflammation, and dissection of their potential to promote autoimmunity and inflammation. Related work involves determination of tissue environmental factors that regulate T cell metabolism and effector function at inflammatory sites, such as tissues damaged in autoimmunity.
Coauthors
Research Interests
Antigens, Differentiation, T-Lymphocyte; Autoimmune Diseases; Biology; Immunity; Lupus Erythematosus, Systemic; Investigative Techniques; Rheumatology; Cytokines
Selected Publications
- Spatial profiling of chromatin accessibility in mouse and human tissuesDeng Y, Bartosovic M, Ma S, Zhang D, Kukanja P, Xiao Y, Su G, Liu Y, Qin X, Rosoklija GB, Dwork AJ, Mann JJ, Xu ML, Halene S, Craft JE, Leong KW, Boldrini M, Castelo-Branco G, Fan R. Spatial profiling of chromatin accessibility in mouse and human tissues Nature 2022, 609: 375-383. PMID: 35978191, PMCID: PMC9452302, DOI: 10.1038/s41586-022-05094-1.
- Spatial-CITE-seq: spatially resolved high-plex protein and whole transcriptome co-mapping.Fan R, Liu Y, DiStasio M, Su G, Asashima H, Enninful A, Qin X, Deng Y, Bordignon P, Cassano M, Tomayko M, Xu M, Halene S, Craft J, Hafler D. Spatial-CITE-seq: spatially resolved high-plex protein and whole transcriptome co-mapping. Research Square 2022 PMID: 35378748, PMCID: PMC8978952, DOI: 10.21203/rs.3.rs-1499315/v1.
- Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infectionZander R, Kasmani MY, Chen Y, Topchyan P, Shen J, Zheng S, Burns R, Ingram J, Cui C, Joshi N, Craft J, Zajac A, Cui W. Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infection Immunity 2022, 55: 475-493.e5. PMID: 35216666, PMCID: PMC8916994, DOI: 10.1016/j.immuni.2022.01.018.
- High-affinity, neutralizing antibodies to SARS-CoV-2 can be made without T follicular helper cellsChen JS, Chow RD, Song E, Mao T, Israelow B, Kamath K, Bozekowski J, Haynes WA, Filler RB, Menasche BL, Wei J, Alfajaro MM, Song W, Peng L, Carter L, Weinstein JS, Gowthaman U, Chen S, Craft J, Shon JC, Iwasaki A, Wilen CB, Eisenbarth SC. High-affinity, neutralizing antibodies to SARS-CoV-2 can be made without T follicular helper cells Science Immunology 2022, 7: eabl5652. PMID: 34914544, PMCID: PMC8977051, DOI: 10.1126/sciimmunol.abl5652.
- Development of Tbet- and CD11c-expressing B cells in a viral infection requires T follicular helper cells outside of germinal centersSong W, Antao OQ, Condiff E, Sanchez GM, Chernova I, Zembrzuski K, Steach H, Rubtsova K, Angeletti D, Lemenze A, Laidlaw BJ, Craft J, Weinstein JS. Development of Tbet- and CD11c-expressing B cells in a viral infection requires T follicular helper cells outside of germinal centers Immunity 2022, 55: 290-307.e5. PMID: 35090581, PMCID: PMC8965751, DOI: 10.1016/j.immuni.2022.01.002.
- Lupus nephritis and beyond: Kidney-intrinsic genetic risk for antibody deposition.Chernova I, Craft J. Lupus nephritis and beyond: Kidney-intrinsic genetic risk for antibody deposition. Cell Reports Medicine 2021, 2: 100479. PMID: 35028618, PMCID: PMC8714907, DOI: 10.1016/j.xcrm.2021.100479.
- Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responsesCui C, Wang J, Fagerberg E, Chen PM, Connolly KA, Damo M, Cheung JF, Mao T, Askari AS, Chen S, Fitzgerald B, Foster GG, Eisenbarth SC, Zhao H, Craft J, Joshi NS. Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses Cell 2021, 184: 6101-6118.e13. PMID: 34852236, PMCID: PMC8671355, DOI: 10.1016/j.cell.2021.11.007.
- CD4+ T cells that help B cells – a proposal for uniform nomenclatureEisenbarth SC, Baumjohann D, Craft J, Fazilleau N, Ma CS, Tangye SG, Vinuesa CG, Linterman MA. CD4+ T cells that help B cells – a proposal for uniform nomenclature Trends In Immunology 2021, 42: 658-669. PMID: 34244056, PMCID: PMC8324560, DOI: 10.1016/j.it.2021.06.003.
- ReplyCraft J, Weinstein J. Reply Arthritis & Rheumatology 2021, 73: 1344-1345. PMID: 33682376, DOI: 10.1002/art.41717.
- Type I Interferon–Activated STAT4 Regulation of Follicular Helper T Cell–Dependent Cytokine and Immunoglobulin Production in LupusDong X, Antao OQ, Song W, Sanchez GM, Zembrzuski K, Koumpouras F, Lemenze A, Craft J, Weinstein JS. Type I Interferon–Activated STAT4 Regulation of Follicular Helper T Cell–Dependent Cytokine and Immunoglobulin Production in Lupus Arthritis & Rheumatology 2021, 73: 478-489. PMID: 33512094, PMCID: PMC7914134, DOI: 10.1002/art.41532.
- T Follicular Regulatory Cells: Choreographers of Productive Germinal Center Responses.Lu Y, Craft J. T Follicular Regulatory Cells: Choreographers of Productive Germinal Center Responses. Frontiers In Immunology 2021, 12: 679909. PMID: 34177925, PMCID: PMC8222975, DOI: 10.3389/fimmu.2021.679909.
- CD4+ follicular regulatory T cells optimize the influenza virus–specific B cell responseLu Y, Jiang R, Freyn AW, Wang J, Strohmeier S, Lederer K, Locci M, Zhao H, Angeletti D, O’Connor K, Kleinstein SH, Nachbagauer R, Craft J. CD4+ follicular regulatory T cells optimize the influenza virus–specific B cell response Journal Of Experimental Medicine 2020, 218: e20200547. PMID: 33326020, PMCID: PMC7748821, DOI: 10.1084/jem.20200547.
- Repeat tick exposure elicits distinct immune responses in guinea pigs and miceKurokawa C, Narasimhan S, Vidyarthi A, Booth CJ, Mehta S, Meister L, Diktas H, Strank N, Lynn GE, DePonte K, Craft J, Fikrig E. Repeat tick exposure elicits distinct immune responses in guinea pigs and mice Ticks And Tick-borne Diseases 2020, 11: 101529. PMID: 32993942, PMCID: PMC7530331, DOI: 10.1016/j.ttbdis.2020.101529.
- Kidney tissue hypoxia dictates T cell–mediated injury in murine lupus nephritisChen PM, Wilson PC, Shyer JA, Veselits M, Steach HR, Cui C, Moeckel G, Clark MR, Craft J. Kidney tissue hypoxia dictates T cell–mediated injury in murine lupus nephritis Science Translational Medicine 2020, 12 PMID: 32269165, PMCID: PMC8055156, DOI: 10.1126/scitranslmed.aay1620.
- Georgia Abortion Law and Our Commitment to PatientsCraft JE, Crow MK, Lockshin M, Salmon J, Diamond B, Elkon K, Flood J, Fox D, Gabriel S, Gilkeson G, Hahn B, Hardin J, Koopman W, Seaman WE, Wofsy D, Sergent J, Uknis A, Weinblatt M. Georgia Abortion Law and Our Commitment to Patients Arthritis & Rheumatology 2019, 72: 377-378. PMID: 31637878, DOI: 10.1002/art.41143.
- Spatial and functional heterogeneity of follicular helper T cells in autoimmunity.Seth A, Craft J. Spatial and functional heterogeneity of follicular helper T cells in autoimmunity. Current Opinion In Immunology 2019, 61: 1-9. PMID: 31374450, PMCID: PMC7255639, DOI: 10.1016/j.coi.2019.06.005.
- Impaired ATM activation in B cells is associated with bone resorption in rheumatoid arthritisMensah KA, Chen JW, Schickel JN, Isnardi I, Yamakawa N, Vega-Loza A, Anolik JH, Gatti RA, Gelfand EW, Montgomery RR, Horowitz MC, Craft JE, Meffre E. Impaired ATM activation in B cells is associated with bone resorption in rheumatoid arthritis Science Translational Medicine 2019, 11 PMID: 31748230, PMCID: PMC7167286, DOI: 10.1126/scitranslmed.aaw4626.
- Author Correction: Distinct modes of mitochondrial metabolism uncouple T cell differentiation and functionBailis W, Shyer JA, Zhao J, Canaveras JCG, Al Khazal FJ, Qu R, Steach HR, Bielecki P, Khan O, Jackson R, Kluger Y, Maher LJ, Rabinowitz J, Craft J, Flavell RA. Author Correction: Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function Nature 2019, 573: e2-e2. PMID: 31447485, DOI: 10.1038/s41586-019-1490-y.
- Identification of a T follicular helper cell subset that drives anaphylactic IgEGowthaman U, Chen JS, Zhang B, Flynn WF, Lu Y, Song W, Joseph J, Gertie JA, Xu L, Collet MA, Grassmann JDS, Simoneau T, Chiang D, Berin MC, Craft JE, Weinstein JS, Williams A, Eisenbarth SC. Identification of a T follicular helper cell subset that drives anaphylactic IgE Science 2019, 365 PMID: 31371561, PMCID: PMC6901029, DOI: 10.1126/science.aaw6433.
- Distinct modes of mitochondrial metabolism uncouple T cell differentiation and functionBailis W, Shyer JA, Zhao J, Canaveras JCG, Al Khazal FJ, Qu R, Steach HR, Bielecki P, Khan O, Jackson R, Kluger Y, Maher LJ, Rabinowitz J, Craft J, Flavell RA. Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function Nature 2019, 571: 403-407. PMID: 31217581, PMCID: PMC6939459, DOI: 10.1038/s41586-019-1311-3.
- T follicular helper cell heterogeneity: Time, space, and functionSong W, Craft J. T follicular helper cell heterogeneity: Time, space, and function Immunological Reviews 2019, 288: 85-96. PMID: 30874350, PMCID: PMC6422039, DOI: 10.1111/imr.12740.
- Single-cell RNA sequencing unveils an IL-10-producing helper subset that sustains humoral immunity during persistent infectionXin G, Zander R, Schauder DM, Chen Y, Weinstein JS, Drobyski WR, Tarakanova V, Craft J, Cui W. Single-cell RNA sequencing unveils an IL-10-producing helper subset that sustains humoral immunity during persistent infection Nature Communications 2018, 9: 5037. PMID: 30487586, PMCID: PMC6261948, DOI: 10.1038/s41467-018-07492-4.
- scFTD-seq: freeze-thaw lysis based, portable approach toward highly distributed single-cell 3′ mRNA profilingDura B, Choi JY, Zhang K, Damsky W, Thakral D, Bosenberg M, Craft J, Fan R. scFTD-seq: freeze-thaw lysis based, portable approach toward highly distributed single-cell 3′ mRNA profiling Nucleic Acids Research 2018, 47: gky1173-. PMID: 30462277, PMCID: PMC6379653, DOI: 10.1093/nar/gky1173.
- Human Extrafollicular CD4+ Th Cells Help Memory B Cells Produce Igs.Kim ST, Choi JY, Lainez B, Schulz VP, Karas DE, Baum ED, Setlur J, Gallagher PG, Craft J. Human Extrafollicular CD4+ Th Cells Help Memory B Cells Produce Igs. The Journal Of Immunology 2018, 201: 1359-1372. PMID: 30030323, PMCID: PMC6112860, DOI: 10.4049/jimmunol.1701217.
- Correction: STAT4 and T-bet control follicular helper T cell development in viral infectionsWeinstein JS, Laidlaw BJ, Lu Y, Wang JK, Schulz VP, Li N, Herman EI, Kaech SM, Gallagher PG, Craft J. Correction: STAT4 and T-bet control follicular helper T cell development in viral infections Journal Of Experimental Medicine 2018, 215: 999-999. PMID: 29440270, PMCID: PMC5839754, DOI: 10.1084/jem.2017045702062018c.
- STAT4 and T-bet control follicular helper T cell development in viral infectionsWeinstein JS, Laidlaw BJ, Lu Y, Wang JK, Schulz VP, Li N, Herman EI, Kaech SM, Gallagher PG, Craft J. STAT4 and T-bet control follicular helper T cell development in viral infections Journal Of Experimental Medicine 2017, 215: 337-355. PMID: 29212666, PMCID: PMC5748849, DOI: 10.1084/jem.20170457.
- Interleukin-10 from CD4+ follicular regulatory T cells promotes the germinal center responseLaidlaw BJ, Lu Y, Amezquita RA, Weinstein JS, Vander Heiden JA, Gupta NT, Kleinstein SH, Kaech SM, Craft J. Interleukin-10 from CD4+ follicular regulatory T cells promotes the germinal center response Science Immunology 2017, 2 PMID: 29054998, PMCID: PMC5846620, DOI: 10.1126/sciimmunol.aan4767.
- Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cellsBosurgi L, Cao YG, Cabeza-Cabrerizo M, Tucci A, Hughes LD, Kong Y, Weinstein JS, Licona-Limon P, Schmid ET, Pelorosso F, Gagliani N, Craft JE, Flavell RA, Ghosh S, Rothlin CV. Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells Science 2017, 356: 1072-1076. PMID: 28495875, PMCID: PMC5556699, DOI: 10.1126/science.aai8132.
- Disruption of Pathogenic Cellular Networks by IL-21 Blockade Leads to Disease Amelioration in Murine Lupus.Choi JY, Seth A, Kashgarian M, Terrillon S, Fung E, Huang L, Wang LC, Craft J. Disruption of Pathogenic Cellular Networks by IL-21 Blockade Leads to Disease Amelioration in Murine Lupus. The Journal Of Immunology 2017, 198: 2578-2588. PMID: 28219887, PMCID: PMC5360548, DOI: 10.4049/jimmunol.1601687.
- TFH cells progressively differentiate to regulate the germinal center responseWeinstein JS, Herman EI, Lainez B, Licona-Limón P, Esplugues E, Flavell R, Craft J. TFH cells progressively differentiate to regulate the germinal center response Nature Immunology 2016, 17: 1197-1205. PMID: 27573866, PMCID: PMC5030190, DOI: 10.1038/ni.3554.
- The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunityChan PY, Carrera Silva EA, De Kouchkovsky D, Joannas LD, Hao L, Hu D, Huntsman S, Eng C, Licona-Limón P, Weinstein JS, Herbert DR, Craft JE, Flavell RA, Repetto S, Correale J, Burchard EG, Torgerson DG, Ghosh S, Rothlin CV. The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity Science 2016, 352: 99-103. PMID: 27034374, PMCID: PMC4935984, DOI: 10.1126/science.aaf1358.
- The multifaceted role of CD4+ T cells in CD8+ T cell memoryLaidlaw BJ, Craft JE, Kaech SM. The multifaceted role of CD4+ T cells in CD8+ T cell memory Nature Reviews Immunology 2016, 16: 102-111. PMID: 26781939, PMCID: PMC4860014, DOI: 10.1038/nri.2015.10.
- IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T CellsBrodeur TY, Robidoux TE, Weinstein JS, Craft J, Swain SL, Marshak-Rothstein A. IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells The Journal Of Immunology 2015, 195: 5251-5260. PMID: 26519529, PMCID: PMC4655158, DOI: 10.4049/jimmunol.1500777.
- Reply: To PMID 25581113.Choi J, Craft J. Reply: To PMID 25581113. Arthritis & Rheumatology (Hoboken, N.J.) 2015, 67: 3094-5. PMID: 26245163, DOI: 10.1002/art.39290.
- A Critical Role of IL-21-Induced BATF in Sustaining CD8-T-Cell-Mediated Chronic Viral ControlXin G, Schauder DM, Lainez B, Weinstein JS, Dai Z, Chen Y, Esplugues E, Wen R, Wang D, Parish IA, Zajac AJ, Craft J, Cui W. A Critical Role of IL-21-Induced BATF in Sustaining CD8-T-Cell-Mediated Chronic Viral Control Cell Reports 2015, 13: 1118-1124. PMID: 26527008, PMCID: PMC4859432, DOI: 10.1016/j.celrep.2015.09.069.
- The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T CellsRay JP, Staron MM, Shyer JA, Ho PC, Marshall HD, Gray SM, Laidlaw BJ, Araki K, Ahmed R, Kaech SM, Craft J. The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells Immunity 2015, 43: 690-702. PMID: 26410627, PMCID: PMC4618086, DOI: 10.1016/j.immuni.2015.08.017.
- Production of IL-10 by CD4+ regulatory T cells during the resolution of infection promotes the maturation of memory CD8+ T cellsLaidlaw BJ, Cui W, Amezquita RA, Gray SM, Guan T, Lu Y, Kobayashi Y, Flavell RA, Kleinstein SH, Craft J, Kaech SM. Production of IL-10 by CD4+ regulatory T cells during the resolution of infection promotes the maturation of memory CD8+ T cells Nature Immunology 2015, 16: 871-879. PMID: 26147684, PMCID: PMC4713030, DOI: 10.1038/ni.3224.
- Circulating Follicular Helper–Like T Cells in Systemic Lupus Erythematosus: Association With Disease ActivityChoi J, Ho J, Pasoto SG, Bunin V, Kim ST, Carrasco S, Borba EF, Gonçalves CR, Costa PR, Kallas EG, Bonfa E, Craft J. Circulating Follicular Helper–Like T Cells in Systemic Lupus Erythematosus: Association With Disease Activity Arthritis & Rheumatology 2015, 67: 988-999. PMID: 25581113, PMCID: PMC4450082, DOI: 10.1002/art.39020.
- Local Triggering of the ICOS Coreceptor by CD11c+ Myeloid Cells Drives Organ Inflammation in LupusTeichmann LL, Cullen JL, Kashgarian M, Dong C, Craft J, Shlomchik MJ. Local Triggering of the ICOS Coreceptor by CD11c+ Myeloid Cells Drives Organ Inflammation in Lupus Immunity 2015, 42: 552-565. PMID: 25786178, PMCID: PMC4456685, DOI: 10.1016/j.immuni.2015.02.015.
- PTENtiating autoimmunity through Treg cell deregulation.Ray JP, Craft J. PTENtiating autoimmunity through Treg cell deregulation. Nature Immunology 2015, 16: 139-40. PMID: 25594458, PMCID: PMC4447107, DOI: 10.1038/ni.3082.
- The transforming growth factor beta signaling pathway is critical for the formation of CD4 T follicular helper cells and isotype-switched antibody responses in the lung mucosaMarshall HD, Ray JP, Laidlaw BJ, Zhang N, Gawande D, Staron MM, Craft J, Kaech SM. The transforming growth factor beta signaling pathway is critical for the formation of CD4 T follicular helper cells and isotype-switched antibody responses in the lung mucosa ELife 2015, 4: e04851. PMID: 25569154, PMCID: PMC4337607, DOI: 10.7554/elife.04851.
- Global transcriptome analysis and enhancer landscape of human primary T follicular helper and T effector lymphocytesWeinstein JS, Lezon-Geyda K, Maksimova Y, Craft S, Zhang Y, Su M, Schulz VP, Craft J, Gallagher PG. Global transcriptome analysis and enhancer landscape of human primary T follicular helper and T effector lymphocytes Blood 2014, 124: 3719-3729. PMID: 25331115, PMCID: PMC4263981, DOI: 10.1182/blood-2014-06-582700.
- CD4+ T Cell Help Guides Formation of CD103+ Lung-Resident Memory CD8+ T Cells during Influenza Viral InfectionLaidlaw BJ, Zhang N, Marshall HD, Staron MM, Guan T, Hu Y, Cauley LS, Craft J, Kaech SM. CD4+ T Cell Help Guides Formation of CD103+ Lung-Resident Memory CD8+ T Cells during Influenza Viral Infection Immunity 2014, 41: 633-645. PMID: 25308332, PMCID: PMC4324721, DOI: 10.1016/j.immuni.2014.09.007.
- Dynamic signaling by T follicular helper cells during germinal center B cell selectionShulman Z, Gitlin AD, Weinstein JS, Lainez B, Esplugues E, Flavell RA, Craft JE, Nussenzweig MC. Dynamic signaling by T follicular helper cells during germinal center B cell selection Science 2014, 345: 1058-1062. PMID: 25170154, PMCID: PMC4519234, DOI: 10.1126/science.1257861.
- PPARγ Negatively Regulates T Cell Activation to Prevent Follicular Helper T Cells and Germinal Center FormationPark HJ, Kim DH, Choi JY, Kim WJ, Kim JY, Senejani AG, Hwang SS, Kim LK, Tobiasova Z, Lee GR, Craft J, Bothwell AL, Choi JM. PPARγ Negatively Regulates T Cell Activation to Prevent Follicular Helper T Cells and Germinal Center Formation PLOS ONE 2014, 9: e99127. PMID: 24921943, PMCID: PMC4055678, DOI: 10.1371/journal.pone.0099127.
- B Cells in T Follicular Helper Cell Development and Function: Separable Roles in Delivery of ICOS Ligand and AntigenWeinstein JS, Bertino SA, Hernandez SG, Poholek AC, Teplitzky TB, Nowyhed HN, Craft J. B Cells in T Follicular Helper Cell Development and Function: Separable Roles in Delivery of ICOS Ligand and Antigen The Journal Of Immunology 2014, 192: 3166-3179. PMID: 24610013, PMCID: PMC3991608, DOI: 10.4049/jimmunol.1302617.
- Transcription Factor STAT3 and Type I Interferons Are Corepressive Insulators for Differentiation of Follicular Helper and T Helper 1 CellsRay JP, Marshall HD, Laidlaw BJ, Staron MM, Kaech SM, Craft J. Transcription Factor STAT3 and Type I Interferons Are Corepressive Insulators for Differentiation of Follicular Helper and T Helper 1 Cells Immunity 2014, 40: 367-377. PMID: 24631156, PMCID: PMC3992517, DOI: 10.1016/j.immuni.2014.02.005.
- Transfer of antigen from human B cells to dendritic cellsHarvey BP, Raycroft MT, Quan TE, Rudenga BJ, Roman RM, Craft J, Mamula MJ. Transfer of antigen from human B cells to dendritic cells Molecular Immunology 2013, 58: 56-65. PMID: 24309484, PMCID: PMC4234097, DOI: 10.1016/j.molimm.2013.10.013.
- The nanomaterial-dependent modulation of dendritic cells and its potential influence on therapeutic immunosuppression in lupusLook M, Saltzman WM, Craft J, Fahmy TM. The nanomaterial-dependent modulation of dendritic cells and its potential influence on therapeutic immunosuppression in lupus Biomaterials 2013, 35: 1089-1095. PMID: 24183697, PMCID: PMC4164020, DOI: 10.1016/j.biomaterials.2013.10.046.
- CD301b+ Dermal Dendritic Cells Drive T Helper 2 Cell-Mediated ImmunityKumamoto Y, Linehan M, Weinstein JS, Laidlaw BJ, Craft JE, Iwasaki A. CD301b+ Dermal Dendritic Cells Drive T Helper 2 Cell-Mediated Immunity Immunity 2013, 39: 733-743. PMID: 24076051, PMCID: PMC3819035, DOI: 10.1016/j.immuni.2013.08.029.
- Roquin paralogs add a new dimension to ICOS regulation.Bertino SA, Craft J. Roquin paralogs add a new dimension to ICOS regulation. Immunity 2013, 38: 624-6. PMID: 23601678, PMCID: PMC3786165, DOI: 10.1016/j.immuni.2013.03.007.
- Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus in miceLook M, Stern E, Wang QA, DiPlacido LD, Kashgarian M, Craft J, Fahmy TM. Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus in mice Journal Of Clinical Investigation 2013, 123: 1741-1749. PMID: 23454752, PMCID: PMC3613921, DOI: 10.1172/jci65907.
- Accumulation of peripheral autoreactive B cells in the absence of functional human regulatory T cellsKinnunen T, Chamberlain N, Morbach H, Choi J, Kim S, Craft J, Mayer L, Cancrini C, Passerini L, Bacchetta R, Ochs HD, Torgerson TR, Meffre E. Accumulation of peripheral autoreactive B cells in the absence of functional human regulatory T cells Blood 2012, 121: 1595-1603. PMID: 23223361, PMCID: PMC3587322, DOI: 10.1182/blood-2012-09-457465.
- The pathogenesis of systemic lupus erythematosus-an update.Choi J, Kim ST, Craft J. The pathogenesis of systemic lupus erythematosus-an update. Current Opinion In Immunology 2012, 24: 651-7. PMID: 23131610, PMCID: PMC3508331, DOI: 10.1016/j.coi.2012.10.004.
- IL-7Rαlow memory CD8+ T cells are significantly elevated in patients with systemic lupus erythematosusKim JS, Cho BA, Sim JH, Shah K, Woo CM, Lee EB, Lee DS, Kang JS, Lee WJ, Park CG, Craft J, Kang I, Kim HR. IL-7Rαlow memory CD8+ T cells are significantly elevated in patients with systemic lupus erythematosus Rheumatology 2012, 51: 1587-1594. PMID: 22661557, PMCID: PMC3418646, DOI: 10.1093/rheumatology/kes100.
- Follicular helper T cells in immunity and systemic autoimmunityCraft JE. Follicular helper T cells in immunity and systemic autoimmunity Nature Reviews Rheumatology 2012, 8: 337-347. PMID: 22549246, PMCID: PMC3604997, DOI: 10.1038/nrrheum.2012.58.
- T cells that promote B‐Cell maturation in systemic autoimmunityWeinstein JS, Hernandez SG, Craft J. T cells that promote B‐Cell maturation in systemic autoimmunity Immunological Reviews 2012, 247: 160-171. PMID: 22500839, PMCID: PMC3334351, DOI: 10.1111/j.1600-065x.2012.01122.x.
- Caspase-activated DNase is required for maintenance of tolerance to lupus nuclear autoantigens.Jog NR, Frisoni L, Shi Q, Monestier M, Hernandez S, Craft J, Prak ET, Caricchio R. Caspase-activated DNase is required for maintenance of tolerance to lupus nuclear autoantigens. Arthritis And Rheumatism 2012, 64: 1247-56. PMID: 22127758, PMCID: PMC3292632, DOI: 10.1002/art.33448.
- IL-21 receptor is required for the systemic accumulation of activated B and T lymphocytes in MRL/MpJ-Fas(lpr/lpr)/J mice.Rankin AL, Guay H, Herber D, Bertino SA, Duzanski TA, Carrier Y, Keegan S, Senices M, Stedman N, Ryan M, Bloom L, Medley Q, Collins M, Nickerson-Nutter C, Craft J, Young D, Dunussi-Joannopoulos K. IL-21 receptor is required for the systemic accumulation of activated B and T lymphocytes in MRL/MpJ-Fas(lpr/lpr)/J mice. Journal Of Immunology (Baltimore, Md. : 1950) 2012, 188: 1656-67. PMID: 22231702, PMCID: PMC3618484, DOI: 10.4049/jimmunol.1003871.
- IL-10 signaling in CD4+ T cells is critical for the pathogenesis of collagen-induced arthritisTao J, Kamanaka M, Hao J, Hao Z, Jiang X, Craft JE, Flavell RA, Wu Z, Hong Z, Zhao L, Yin Z. IL-10 signaling in CD4+ T cells is critical for the pathogenesis of collagen-induced arthritis Arthritis Research & Therapy 2011, 13: r212. PMID: 22192790, PMCID: PMC3334665, DOI: 10.1186/ar3545.
- An Interleukin-21- Interleukin-10-STAT3 Pathway Is Critical for Functional Maturation of Memory CD8+ T CellsCui W, Liu Y, Weinstein JS, Craft J, Kaech SM. An Interleukin-21- Interleukin-10-STAT3 Pathway Is Critical for Functional Maturation of Memory CD8+ T Cells Immunity 2011, 35: 792-805. PMID: 22118527, PMCID: PMC3431922, DOI: 10.1016/j.immuni.2011.09.017.
- Differential Expression of Ly6C and T-bet Distinguish Effector and Memory Th1 CD4+ Cell Properties during Viral InfectionMarshall HD, Chandele A, Jung YW, Meng H, Poholek AC, Parish IA, Rutishauser R, Cui W, Kleinstein SH, Craft J, Kaech SM. Differential Expression of Ly6C and T-bet Distinguish Effector and Memory Th1 CD4+ Cell Properties during Viral Infection Immunity 2011, 35: 633-646. PMID: 22018471, PMCID: PMC3444169, DOI: 10.1016/j.immuni.2011.08.016.
- The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in MiceTang W, Lu Y, Tian QY, Zhang Y, Guo FJ, Liu GY, Syed NM, Lai Y, Lin EA, Kong L, Su J, Yin F, Ding AH, Zanin-Zhorov A, Dustin ML, Tao J, Craft J, Yin Z, Feng JQ, Abramson SB, Yu XP, Liu CJ. The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice Science 2011, 332: 478-484. PMID: 21393509, PMCID: PMC3104397, DOI: 10.1126/science.1199214.
- Dissecting the Immune Cell Mayhem That Drives Lupus PathogenesisCraft JE. Dissecting the Immune Cell Mayhem That Drives Lupus Pathogenesis Science Translational Medicine 2011, 3: 73ps9. PMID: 21389262, PMCID: PMC3694130, DOI: 10.1126/scitranslmed.3002138.
- Systemic autoimmunity and lymphoproliferation are associated with excess IL-7 and inhibited by IL-7Rα blockade.Gonzalez-Quintial R, Lawson BR, Scatizzi JC, Craft J, Kono DH, Baccala R, Theofilopoulos AN. Systemic autoimmunity and lymphoproliferation are associated with excess IL-7 and inhibited by IL-7Rα blockade. PloS One 2011, 6: e27528. PMID: 22102903, PMCID: PMC3213145, DOI: 10.1371/journal.pone.0027528.
- Development of a nanoparticulate formulation of retinoic acid that suppresses Th17 cells and upregulates regulatory T cells.Capurso NA, Look M, Jeanbart L, Nowyhed H, Abraham C, Craft J, Fahmy TM. Development of a nanoparticulate formulation of retinoic acid that suppresses Th17 cells and upregulates regulatory T cells. Self/Nonself 2010, 1: 335-340. PMID: 21487509, PMCID: PMC3062389, DOI: 10.4161/self.1.4.13946.
- Naturally Activated Vγ4 γδ T Cells Play a Protective Role in Tumor Immunity through Expression of EomesoderminHe W, Hao J, Dong S, Gao Y, Tao J, Chi H, Flavell R, O’Brien R, Born WK, Craft J, Han J, Wang P, Zhao L, Wu J, Yin Z. Naturally Activated Vγ4 γδ T Cells Play a Protective Role in Tumor Immunity through Expression of Eomesodermin The Journal Of Immunology 2010, 185: 126-133. PMID: 20525896, PMCID: PMC3813958, DOI: 10.4049/jimmunol.0903767.
- In Vivo Regulation of Bcl6 and T Follicular Helper Cell DevelopmentPoholek AC, Hansen K, Hernandez SG, Eto D, Chandele A, Weinstein JS, Dong X, Odegard JM, Kaech SM, Dent AL, Crotty S, Craft J. In Vivo Regulation of Bcl6 and T Follicular Helper Cell Development The Journal Of Immunology 2010, 185: 313-326. PMID: 20519643, PMCID: PMC2891136, DOI: 10.4049/jimmunol.0904023.
- Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosusShah K, Lee WW, Lee SH, Kim SH, Kang SW, Craft J, Kang I. Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus Arthritis Research & Therapy 2010, 12: r53. PMID: 20334681, PMCID: PMC2888202, DOI: 10.1186/ar2964.
- Epstein‐Barr virus promotes interferon‐α production by plasmacytoid dendritic cellsQuan TE, Roman RM, Rudenga BJ, Holers VM, Craft JE. Epstein‐Barr virus promotes interferon‐α production by plasmacytoid dendritic cells Arthritis & Rheumatism 2010, 62: 1693-1701. PMID: 20178121, PMCID: PMC2885535, DOI: 10.1002/art.27408.
- Emerging from the shadows: follicular helper T cells in autoimmunity.DiPlacido LD, Craft J. Emerging from the shadows: follicular helper T cells in autoimmunity. Arthritis And Rheumatism 2010, 62: 6-8. PMID: 20039423, PMCID: PMC2806501, DOI: 10.1002/art.25045.
- Thymic self-reactivity selects natural interleukin 17–producing T cells that can regulate peripheral inflammationMarks BR, Nowyhed HN, Choi JY, Poholek AC, Odegard JM, Flavell RA, Craft J. Thymic self-reactivity selects natural interleukin 17–producing T cells that can regulate peripheral inflammation Nature Immunology 2009, 10: 1125-1132. PMID: 19734905, PMCID: PMC2751862, DOI: 10.1038/ni.1783.
- Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation.Johnston RJ, Poholek AC, DiToro D, Yusuf I, Eto D, Barnett B, Dent AL, Craft J, Crotty S. Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science (New York, N.Y.) 2009, 325: 1006-10. PMID: 19608860, PMCID: PMC2766560, DOI: 10.1126/science.1175870.
- Competing for help: new insights into the function of follicular helper T cells.Poholek AC, Craft J. Competing for help: new insights into the function of follicular helper T cells. Immunology And Cell Biology 2009, 87: 438-9. PMID: 19381158, PMCID: PMC3612525, DOI: 10.1038/icb.2009.26.
- Barrier immunity and IL-17.Marks BR, Craft J. Barrier immunity and IL-17. Seminars In Immunology 2009, 21: 164-71. PMID: 19386512, PMCID: PMC2692766, DOI: 10.1016/j.smim.2009.03.001.
- ICOS Controls Effector Function but Not Trafficking Receptor Expression of Kidney-Infiltrating Effector T Cells in Murine LupusOdegard JM, DiPlacido LD, Greenwald L, Kashgarian M, Kono DH, Dong C, Flavell RA, Craft J. ICOS Controls Effector Function but Not Trafficking Receptor Expression of Kidney-Infiltrating Effector T Cells in Murine Lupus The Journal Of Immunology 2009, 182: 4076-4084. PMID: 19299705, PMCID: PMC2746004, DOI: 10.4049/jimmunol.0800758.
- ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunityOdegard JM, Marks BR, DiPlacido LD, Poholek AC, Kono DH, Dong C, Flavell RA, Craft J. ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity Journal Of Experimental Medicine 2008, 205: 2873-2886. PMID: 18981236, PMCID: PMC2585848, DOI: 10.1084/jem.20080840.
- Editing Antigen Presentation: Antigen Transfer between Human B Lymphocytes and Macrophages Mediated by Class A Scavenger ReceptorsHarvey BP, Quan TE, Rudenga BJ, Roman RM, Craft J, Mamula MJ. Editing Antigen Presentation: Antigen Transfer between Human B Lymphocytes and Macrophages Mediated by Class A Scavenger Receptors The Journal Of Immunology 2008, 181: 4043-4051. PMID: 18768860, PMCID: PMC2701691, DOI: 10.4049/jimmunol.181.6.4043.
- Autoantibodies against cyclophilin in systemic lupus erythematosus and Lyme diseaseKRATZ A, HARDING MW, CRAFT J, MACKWORTH‐YOUNG C, HANDSCHUMACHER RE. Autoantibodies against cyclophilin in systemic lupus erythematosus and Lyme disease Clinical & Experimental Immunology 2008, 90: 422-427. PMID: 1458678, PMCID: PMC1554566, DOI: 10.1111/j.1365-2249.1992.tb05862.x.
- Scavenger receptor type AI mediates antigen transfer from human B cells to other APCsHarvey B, Quan T, Roman R, Rudenga B, Craft J, Mamula M. Scavenger receptor type AI mediates antigen transfer from human B cells to other APCs The FASEB Journal 2008, 22: 1068.14-1068.14. DOI: 10.1096/fasebj.22.1_supplement.1068.14.
- CD4 T Cells That Promote Extrafollicular B Cell ResponsesPoholek A, Odegard J, Craft J. CD4 T Cells That Promote Extrafollicular B Cell Responses The FASEB Journal 2008, 22: 846.3-846.3. DOI: 10.1096/fasebj.22.1_supplement.846.3.
- The Role of ICOS in Peripheral Inflammation in LupusEardley L, Odegard J, Craft J. The Role of ICOS in Peripheral Inflammation in Lupus The FASEB Journal 2008, 22: 668.18-668.18. DOI: 10.1096/fasebj.22.1_supplement.668.18.
- Epigenetic and Transcriptional Programs Lead to Default IFN-γ Production by γδ T CellsChen L, He W, Kim ST, Tao J, Gao Y, Chi H, Intlekofer AM, Harvey B, Reiner SL, Yin Z, Flavell RA, Craft J. Epigenetic and Transcriptional Programs Lead to Default IFN-γ Production by γδ T Cells The Journal Of Immunology 2007, 178: 2730-2736. PMID: 17312115, DOI: 10.4049/jimmunol.178.5.2730.
- Abrogation of skin disease in LUPUS‐prone MRL/FASlpr mice by means of a novel tylophorine analogChoi J, Gao W, Odegard J, Shiah H, Kashgarian M, McNiff JM, Baker DC, Cheng Y, Craft J. Abrogation of skin disease in LUPUS‐prone MRL/FASlpr mice by means of a novel tylophorine analog Arthritis & Rheumatism 2006, 54: 3277-3283. PMID: 17009262, DOI: 10.1002/art.22119.
- γδ T Cells Facilitate Adaptive Immunity against West Nile Virus Infection in MiceWang T, Gao Y, Scully E, Davis CT, Anderson JF, Welte T, Ledizet M, Koski R, Madri JA, Barrett A, Yin Z, Craft J, Fikrig E. γδ T Cells Facilitate Adaptive Immunity against West Nile Virus Infection in Mice The Journal Of Immunology 2006, 177: 1825-1832. PMID: 16849493, DOI: 10.4049/jimmunol.177.3.1825.
- Gamma Interferon Plays a Crucial Early Antiviral Role in Protection against West Nile Virus InfectionShrestha B, Wang T, Samuel MA, Whitby K, Craft J, Fikrig E, Diamond MS. Gamma Interferon Plays a Crucial Early Antiviral Role in Protection against West Nile Virus Infection Journal Of Virology 2006, 80: 5338-5348. PMID: 16699014, PMCID: PMC1472130, DOI: 10.1128/jvi.00274-06.
- Role for macrophage migration inhibitory factor in asthmaMizue Y, Ghani S, Leng L, McDonald C, Kong P, Baugh J, Lane SJ, Craft J, Nishihira J, Donnelly SC, Zhu Z, Bucala R. Role for macrophage migration inhibitory factor in asthma Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 14410-14415. PMID: 16186482, PMCID: PMC1242335, DOI: 10.1073/pnas.0507189102.
- Naive CD4+ T Cells from Lupus-Prone Fas-Intact MRL Mice Display TCR-Mediated Hyperproliferation Due to Intrinsic Threshold Defects in ActivationZielinski CE, Jacob SN, Bouzahzah F, Ehrlich BE, Craft J. Naive CD4+ T Cells from Lupus-Prone Fas-Intact MRL Mice Display TCR-Mediated Hyperproliferation Due to Intrinsic Threshold Defects in Activation The Journal Of Immunology 2005, 174: 5100-5109. PMID: 15814741, DOI: 10.4049/jimmunol.174.8.5100.
- Association of reduced CD4 T cell responses specific to varicella zoster virus with high incidence of herpes zoster in patients with systemic lupus erythematosus.Park HB, Kim KC, Park JH, Kang TY, Lee HS, Kim TH, Jun JB, Bae SC, Yoo DH, Craft J, Jung S. Association of reduced CD4 T cell responses specific to varicella zoster virus with high incidence of herpes zoster in patients with systemic lupus erythematosus. The Journal Of Rheumatology 2004, 31: 2151-5. PMID: 15517626.
- Resistance to Development of Collagen-Induced Arthritis in C57BL/6 Mice Is Due to a Defect in Secondary, but Not in Primary, Immune ResponsePan M, Kang I, Craft J, Yin Z. Resistance to Development of Collagen-Induced Arthritis in C57BL/6 Mice Is Due to a Defect in Secondary, but Not in Primary, Immune Response Journal Of Clinical Immunology 2004, 24: 481-491. PMID: 15359107, DOI: 10.1023/b:joci.0000040919.16739.44.
- Age-Associated Change in the Frequency of Memory CD4+ T Cells Impairs Long Term CD4+ T Cell Responses to Influenza VaccineKang I, Hong MS, Nolasco H, Park SH, Dan JM, Choi JY, Craft J. Age-Associated Change in the Frequency of Memory CD4+ T Cells Impairs Long Term CD4+ T Cell Responses to Influenza Vaccine The Journal Of Immunology 2004, 173: 673-681. PMID: 15210831, DOI: 10.4049/jimmunol.173.1.673.
- Activation of Naive CD4+ T Cells In Vivo by a Self-Peptide Mimic: Mechanism of Tolerance Maintenance and Preservation of ImmunityChoi JY, Craft J. Activation of Naive CD4+ T Cells In Vivo by a Self-Peptide Mimic: Mechanism of Tolerance Maintenance and Preservation of Immunity The Journal Of Immunology 2004, 172: 7399-7407. PMID: 15187117, DOI: 10.4049/jimmunol.172.12.7399.
- The Centromeric Region of Chromosome 7 from MRL Mice (Lmb3) Is an Epistatic Modifier of Fas for Autoimmune Disease ExpressionKong PL, Morel L, Croker BP, Craft J. The Centromeric Region of Chromosome 7 from MRL Mice (Lmb3) Is an Epistatic Modifier of Fas for Autoimmune Disease Expression The Journal Of Immunology 2004, 172: 2785-2794. PMID: 14978078, DOI: 10.4049/jimmunol.172.5.2785.
- Defective Control of Latent Epstein-Barr Virus Infection in Systemic Lupus ErythematosusKang I, Quan T, Nolasco H, Park SH, Hong MS, Crouch J, Pamer EG, Howe JG, Craft J. Defective Control of Latent Epstein-Barr Virus Infection in Systemic Lupus Erythematosus The Journal Of Immunology 2004, 172: 1287-1294. PMID: 14707107, DOI: 10.4049/jimmunol.172.2.1287.
- Age-dependent Requirement for γδ T Cells in the Primary but Not Secondary Protective Immune Response against an Intestinal ParasiteRamsburg E, Tigelaar R, Craft J, Hayday A. Age-dependent Requirement for γδ T Cells in the Primary but Not Secondary Protective Immune Response against an Intestinal Parasite Journal Of Experimental Medicine 2003, 198: 1403-1414. PMID: 14597739, PMCID: PMC2194243, DOI: 10.1084/jem.20030050.
- Intrastructural help in diversification of humoral autoimmune responsesFATENEJAD S, CRAFT J. Intrastructural help in diversification of humoral autoimmune responses Clinical & Experimental Immunology 2003, 106: 1-4. PMID: 8870690, PMCID: PMC2200562, DOI: 10.1046/j.1365-2249.1996.d01-821.x.
- Role of the H‐2 haplotype in Fas‐intact lupus‐prone MRL mice: association with autoantibodies but not renal diseaseKong PL, Zhu T, Madaio MP, Craft J. Role of the H‐2 haplotype in Fas‐intact lupus‐prone MRL mice: association with autoantibodies but not renal disease Arthritis & Rheumatism 2003, 48: 2992-2995. PMID: 14558109, DOI: 10.1002/art.11308.
- IFN-γ-Producing γδ T Cells Help Control Murine West Nile Virus InfectionWang T, Scully E, Yin Z, Kim JH, Wang S, Yan J, Mamula M, Anderson JF, Craft J, Fikrig E. IFN-γ-Producing γδ T Cells Help Control Murine West Nile Virus Infection The Journal Of Immunology 2003, 171: 2524-2531. PMID: 12928402, DOI: 10.4049/jimmunol.171.5.2524.
- γδ T Cells Provide an Early Source of Interferon γ in Tumor ImmunityGao Y, Yang W, Pan M, Scully E, Girardi M, Augenlicht LH, Craft J, Yin Z. γδ T Cells Provide an Early Source of Interferon γ in Tumor Immunity Journal Of Experimental Medicine 2003, 198: 433-442. PMID: 12900519, PMCID: PMC2194096, DOI: 10.1084/jem.20030584.
- Oxazolone and diclofenac-induced popliteal lymph node assay reactions are attenuated in mice orally pretreated with the respective compound: potential role for the induction of regulatory mechanisms following enteric administration.Gutting BW, Bouzahzah F, Kong PL, Updyke LW, Amacher DE, Craft J. Oxazolone and diclofenac-induced popliteal lymph node assay reactions are attenuated in mice orally pretreated with the respective compound: potential role for the induction of regulatory mechanisms following enteric administration. Toxicology And Applied Pharmacology 2003, 189: 120-33. PMID: 12781630, DOI: 10.1016/s0041-008x(03)00091-7.
- Intrinsic T Cell Defects in Systemic AutoimmunityKONG PL, ODEGARD JM, BOUZAHZAH F, CHOI J, EARDLEY LD, ZIELINSKI CE, CRAFT JE. Intrinsic T Cell Defects in Systemic Autoimmunity Annals Of The New York Academy Of Sciences 2003, 987: 60-67. PMID: 12727624, DOI: 10.1111/j.1749-6632.2003.tb06033.x.
- STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: A critical role of STAT3 in innate immunityWelte T, Zhang SS, Wang T, Zhang Z, Hesslein DG, Yin Z, Kano A, Iwamoto Y, Li E, Craft JE, Bothwell AL, Fikrig E, Koni PA, Flavell RA, Fu XY. STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: A critical role of STAT3 in innate immunity Proceedings Of The National Academy Of Sciences Of The United States Of America 2003, 100: 1879-1884. PMID: 12571365, PMCID: PMC149927, DOI: 10.1073/pnas.0237137100.
- CD4+ T Cells from Lupus-Prone Mice Avoid Antigen-Specific Tolerance Induction In VivoBouzahzah F, Jung S, Craft J. CD4+ T Cells from Lupus-Prone Mice Avoid Antigen-Specific Tolerance Induction In Vivo The Journal Of Immunology 2003, 170: 741-748. PMID: 12517936, DOI: 10.4049/jimmunol.170.2.741.
- The transmembrane form of TNF-alpha drives autoantibody production in the absence of CD154: studies using MRL/Mp-Fas(lpr) mice.Fujii T, Okada M, Mimori T, Craft J. The transmembrane form of TNF-alpha drives autoantibody production in the absence of CD154: studies using MRL/Mp-Fas(lpr) mice. Clinical And Experimental Immunology 2002, 130: 224-32. PMID: 12390309, PMCID: PMC1906522, DOI: 10.1046/j.1365-2249.2002.01982.x.
- IL-10 Regulates Murine LupusYin Z, Bahtiyar G, Zhang N, Liu L, Zhu P, Robert ME, McNiff J, Madaio MP, Craft J. IL-10 Regulates Murine Lupus The Journal Of Immunology 2002, 169: 2148-2155. PMID: 12165544, DOI: 10.4049/jimmunol.169.4.2148.
- Transgenic Overexpression of Interleukin (IL)-10 in the Lung Causes Mucus Metaplasia, Tissue Inflammation, and Airway Remodeling via IL-13-dependent and -independent Pathways*Lee CG, Homer RJ, Cohn L, Link H, Jung S, Craft JE, Graham BS, Johnson TR, Elias JA. Transgenic Overexpression of Interleukin (IL)-10 in the Lung Causes Mucus Metaplasia, Tissue Inflammation, and Airway Remodeling via IL-13-dependent and -independent Pathways* Journal Of Biological Chemistry 2002, 277: 35466-35474. PMID: 12107190, DOI: 10.1074/jbc.m206395200.
- Detection of anti-elongation factor 2 kinase (calmodulin-dependent protein kinase III) antibodies in patients with systemic lupus erythematosus.Arora S, Yang JM, Craft J, Hait W. Detection of anti-elongation factor 2 kinase (calmodulin-dependent protein kinase III) antibodies in patients with systemic lupus erythematosus. Biochemical And Biophysical Research Communications 2002, 293: 1073-6. PMID: 12051769, DOI: 10.1016/S0006-291X(02)00324-8.
- Regulation of T cell-dependent autoantibody production by a gammadelta T cell line derived from lupus-prone mice.Fujii T, Okada M, Craft J. Regulation of T cell-dependent autoantibody production by a gammadelta T cell line derived from lupus-prone mice. Cellular Immunology 2002, 217: 23-35. PMID: 12425998, DOI: 10.1016/s0008-8749(02)00509-9.
- T-Bet expression and failure of GATA-3 cross-regulation lead to default production of IFN-gamma by gammadelta T cells.Yin Z, Chen C, Szabo SJ, Glimcher LH, Ray A, Craft J. T-Bet expression and failure of GATA-3 cross-regulation lead to default production of IFN-gamma by gammadelta T cells. Journal Of Immunology (Baltimore, Md. : 1950) 2002, 168: 1566-71. PMID: 11823483, DOI: 10.4049/jimmunol.168.4.1566.
- From T to B and back again: positive feedback in systemic autoimmune diseaseShlomchik M, Craft J, Mamula M. From T to B and back again: positive feedback in systemic autoimmune disease Nature Reviews Immunology 2001, 1: 147-153. PMID: 11905822, DOI: 10.1038/35100573.
- CD4(+) T cells from lupus-prone mice are hyperresponsive to T cell receptor engagement with low and high affinity peptide antigens: a model to explain spontaneous T cell activation in lupus.Vratsanos GS, Jung S, Park YM, Craft J. CD4(+) T cells from lupus-prone mice are hyperresponsive to T cell receptor engagement with low and high affinity peptide antigens: a model to explain spontaneous T cell activation in lupus. The Journal Of Experimental Medicine 2001, 193: 329-37. PMID: 11157053, PMCID: PMC2195926, DOI: 10.1084/jem.193.3.329.
- Roles of Fas and Fas ligand during mammary gland remodelingSong J, Sapi E, Brown W, Nilsen J, Tartaro K, Kacinski B, Craft J, Naftolin F, Mor G. Roles of Fas and Fas ligand during mammary gland remodeling Journal Of Clinical Investigation 2000, 106: 1209-1220. PMID: 11086022, PMCID: PMC381435, DOI: 10.1172/jci10411.
- Dominance of IL-12 over IL-4 in gamma delta T cell differentiation leads to default production of IFN-gamma: failure to down-regulate IL-12 receptor beta 2-chain expression.Yin Z, Zhang DH, Welte T, Bahtiyar G, Jung S, Liu L, Fu XY, Ray A, Craft J. Dominance of IL-12 over IL-4 in gamma delta T cell differentiation leads to default production of IFN-gamma: failure to down-regulate IL-12 receptor beta 2-chain expression. Journal Of Immunology (Baltimore, Md. : 1950) 2000, 164: 3056-64. PMID: 10706694, DOI: 10.4049/jimmunol.164.6.3056.
- gamma delta T cells in autoimmunity.Yin Z, Craft J. gamma delta T cells in autoimmunity. Springer Seminars In Immunopathology 2000, 22: 311-20. PMID: 11116960, DOI: 10.1007/s002810000048.
- Autoreactive T cells in murine lupus: origins and roles in autoantibody production.Craft J, Peng S, Fujii T, Okada M, Fatenejad S. Autoreactive T cells in murine lupus: origins and roles in autoantibody production. Immunologic Research 1999, 19: 245-57. PMID: 10493178, DOI: 10.1007/BF02786492.
- Central T cell tolerance in lupus-prone mice: influence of autoimmune background and the lpr mutation.Fatenejad S, Peng SL, Disorbo O, Craft J. Central T cell tolerance in lupus-prone mice: influence of autoimmune background and the lpr mutation. The Journal Of Immunology 1998, 161: 6427-32. PMID: 9834135, DOI: 10.4049/jimmunol.161.11.6427.
- Influence of antigen organization on the development of lupus autoantibodies.Fatenejad S, Bennett M, Moslehi J, Craft J. Influence of antigen organization on the development of lupus autoantibodies. Arthritis And Rheumatism 1998, 41: 603-12. PMID: 9550469, DOI: 10.1002/1529-0131(199804)41:4<603::AID-ART7>3.0.CO;2-E.
- Perforin protects against autoimmunity in lupus-prone mice.Peng SL, Moslehi J, Robert ME, Craft J. Perforin protects against autoimmunity in lupus-prone mice. Journal Of Immunology (Baltimore, Md. : 1950) 1998, 160: 652-60. PMID: 9551899.
- Self antigens and epitope spreading in systemic autoimmunity.Craft J, Fatenejad S. Self antigens and epitope spreading in systemic autoimmunity. Arthritis And Rheumatism 1997, 40: 1374-82. PMID: 9259415, DOI: 10.1002/art.1780400803.
- The transcriptional activator Sp1, a novel autoantigenSpain T, Sun R, Gradzka M, Lin S, Craft J, Miller G. The transcriptional activator Sp1, a novel autoantigen Arthritis & Rheumatism 1997, 40: 1085-1095. PMID: 9182919, DOI: 10.1002/art.1780400613.
- Roles of interferon-gamma and interleukin-4 in murine lupus.Peng SL, Moslehi J, Craft J. Roles of interferon-gamma and interleukin-4 in murine lupus. The Journal Of Clinical Investigation 1997, 99: 1936-46. PMID: 9109438, PMCID: PMC508018, DOI: 10.1172/JCI119361.
- The regulation of murine lupus.Peng SL, Craft J. The regulation of murine lupus. Annals Of The New York Academy Of Sciences 1997, 815: 128-38. PMID: 9186650, DOI: 10.1111/j.1749-6632.1997.tb52055.x.
- A man with fever and petechiae.Greene WL, Craft J. A man with fever and petechiae. Lancet 1997, 349: 696. PMID: 9078202, DOI: 10.1016/S0140-6736(96)11204-6.
- alpha beta T cell regulation and CD40 ligand dependence in murine systemic autoimmunity.Peng SL, McNiff JM, Madaio MP, Ma J, Owen MJ, Flavell RA, Hayday AC, Craft J. alpha beta T cell regulation and CD40 ligand dependence in murine systemic autoimmunity. The Journal Of Immunology 1997, 158: 2464-70. PMID: 9036998, DOI: 10.4049/jimmunol.158.5.2464.
- Scleroderma: a disease related to damaged proteins?Peng SL, Fatenejad S, Craft J. Scleroderma: a disease related to damaged proteins? Nature Medicine 1997, 3: 276-8. PMID: 9055850, DOI: 10.1038/nm0397-276.
- Revisiting autoantibody profiles in systemic lupus erythematosus.Olhoffer IH, Peng SL, Craft J. Revisiting autoantibody profiles in systemic lupus erythematosus. The Journal Of Rheumatology 1997, 24: 297-302. PMID: 9034986.
- Induction of nonpathologic, humoral autoimmunity in lupus-prone mice by a class II-restricted, transgenic alpha beta T cell. Separation of autoantigen-specific and -nonspecific help.Peng SL, Fatenejad S, Craft J. Induction of nonpathologic, humoral autoimmunity in lupus-prone mice by a class II-restricted, transgenic alpha beta T cell. Separation of autoantigen-specific and -nonspecific help. The Journal Of Immunology 1996, 157: 5225-30. PMID: 8955166, DOI: 10.4049/jimmunol.157.12.5225.
- Propagation and regulation of systemic autoimmunity by gammadelta T cells.Peng SL, Madaio MP, Hayday AC, Craft J. Propagation and regulation of systemic autoimmunity by gammadelta T cells. Journal Of Immunology (Baltimore, Md. : 1950) 1996, 157: 5689-98. PMID: 8955223.
- Autoimmunity to RNA polymerase II is focused at the carboxyl terminal domain of the large subunit.Hirakata M, Kanungo J, Suwa A, Takeda Y, Craft J, Hardin JA. Autoimmunity to RNA polymerase II is focused at the carboxyl terminal domain of the large subunit. Arthritis And Rheumatism 1996, 39: 1886-91. PMID: 8912511, PMCID: PMC6007873, DOI: 10.1002/art.1780391115.
- Systemic autoimmunity in LG/J mice.Peng SL, Madaio MP, Craft J. Systemic autoimmunity in LG/J mice. Immunology Letters 1996, 53: 153-5. PMID: 9024995, DOI: 10.1016/s0165-2478(96)02616-8.
- Association of RNase mitochondrial RNA processing enzyme with ribonuclease P in higher ordered structures in the nucleolus: a possible coordinate role in ribosome biogenesis.Lee B, Matera AG, Ward DC, Craft J. Association of RNase mitochondrial RNA processing enzyme with ribonuclease P in higher ordered structures in the nucleolus: a possible coordinate role in ribosome biogenesis. Proceedings Of The National Academy Of Sciences Of The United States Of America 1996, 93: 11471-11476. PMID: 8876159, PMCID: PMC38081, DOI: 10.1073/pnas.93.21.11471.
- Anti-U5 small nuclear ribonucleoprotein (snRNP) antibodies: a rare anti-U snRNP specificity.Okano Y, Targoff IN, Oddis CV, Fujii T, Kuwana M, Tsuzaka K, Hirakata M, Mimori T, Craft J, Medsger TA. Anti-U5 small nuclear ribonucleoprotein (snRNP) antibodies: a rare anti-U snRNP specificity. Clinical Immunology And Immunopathology 1996, 81: 41-7. PMID: 8808640, DOI: 10.1006/clin.1996.0155.
- PCR-RFLP Genotyping of Murine MHC HaplotypesPeng S, Craft J. PCR-RFLP Genotyping of Murine MHC Haplotypes BioTechniques 1996, 21: 362-368. PMID: 8879564, DOI: 10.2144/96213bm03.
- A tumor-suppressor function for Fas (CD95) revealed in T cell-deficient mice.Peng SL, Robert ME, Hayday AC, Craft J. A tumor-suppressor function for Fas (CD95) revealed in T cell-deficient mice. The Journal Of Experimental Medicine 1996, 184: 1149-54. PMID: 9064331, PMCID: PMC2192794, DOI: 10.1084/jem.184.3.1149.
- Protective antibodies in murine Lyme disease arise independently of CD40 ligand.Fikrig E, Barthold SW, Chen M, Grewal IS, Craft J, Flavell RA. Protective antibodies in murine Lyme disease arise independently of CD40 ligand. The Journal Of Immunology 1996, 157: 1-3. PMID: 8683101, DOI: 10.4049/jimmunol.157.1.1.
- Autoimmune lpr/lpr mice deficient in CD40 ligand: spontaneous Ig class switching with dichotomy of autoantibody responses.Ma J, Xu J, Madaio MP, Peng Q, Zhang J, Grewal IS, Flavell RA, Craft J. Autoimmune lpr/lpr mice deficient in CD40 ligand: spontaneous Ig class switching with dichotomy of autoantibody responses. The Journal Of Immunology 1996, 157: 417-26. PMID: 8683147, DOI: 10.4049/jimmunol.157.1.417.
- Murine lupus in the absence of alpha beta T cells.Peng SL, Madaio MP, Hughes DP, Crispe IN, Owen MJ, Wen L, Hayday AC, Craft J. Murine lupus in the absence of alpha beta T cells. The Journal Of Immunology 1996, 156: 4041-9. PMID: 8621947, DOI: 10.4049/jimmunol.156.10.4041.
- Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells.Wen L, Pao W, Wong FS, Peng Q, Craft J, Zheng B, Kelsoe G, Dianda L, Owen MJ, Hayday AC. Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells. Journal Of Experimental Medicine 1996, 183: 2271-2282. PMID: 8642336, PMCID: PMC2192585, DOI: 10.1084/jem.183.5.2271.
- Autoantibodies to glycyl-transfer RNA synthetase in myositis. Association with dermatomyositis and immunologic heterogeneity.Hirakata M, Suwa A, Takeda Y, Matsuoka Y, Irimajiri S, Targoff IN, Hardin JA, Craft J. Autoantibodies to glycyl-transfer RNA synthetase in myositis. Association with dermatomyositis and immunologic heterogeneity. Arthritis And Rheumatism 1996, 39: 146-51. PMID: 8546723, DOI: 10.1002/art.1780390119.
- MHC class I polymorphism in lupus-prone MRL/Mp mice.Peng SL, Craft J. MHC class I polymorphism in lupus-prone MRL/Mp mice. Immunogenetics 1996, 44: 407-8. PMID: 8781130.
- T cells in murine lupus: propagation and regulation of disease.Peng SL, Craft J. T cells in murine lupus: propagation and regulation of disease. Molecular Biology Reports 1996, 23: 247-51. PMID: 9112236, DOI: 10.1007/BF00351176.
- Spliceosomal snRNPs AutoantibodiesPeng S, Craft J. Spliceosomal snRNPs Autoantibodies 1996, 774-782. DOI: 10.1016/b978-044482383-0/50119-9.
- Safety and immunogenicity of an outer surface protein A vaccine in subjects with previous Lyme disease.Schoen RT, Meurice F, Brunet CM, Cretella S, Krause DS, Craft JE, Fikrig E. Safety and immunogenicity of an outer surface protein A vaccine in subjects with previous Lyme disease. The Journal Of Infectious Diseases 1995, 172: 1324-9. PMID: 7594671, DOI: 10.1093/infdis/172.5.1324.
- T cells with gamma/delta T cell receptors (TCR) of intestinal type are preferentially expanded in TCR-alpha-deficient lpr mice.Hughes DP, Hayday A, Craft JE, Owen MJ, Crispe IN. T cells with gamma/delta T cell receptors (TCR) of intestinal type are preferentially expanded in TCR-alpha-deficient lpr mice. Journal Of Experimental Medicine 1995, 182: 233-241. PMID: 7540652, PMCID: PMC2192080, DOI: 10.1084/jem.182.1.233.
- Molecular Structure and Function of Autoantigens in Systemic SclerosisLee B, Craft J. Molecular Structure and Function of Autoantigens in Systemic Sclerosis International Reviews Of Immunology 1995, 12: 129-144. PMID: 7650417, DOI: 10.3109/08830189509056708.
- Pattern of anti-small nuclear ribonucleoprotein antibodies in MRL/Mp-lpr/lpr mice suggests that the intact U1 snRNP particle is their autoimmunogenic target.Fatenejad S, Brooks W, Schwartz A, Craft J. Pattern of anti-small nuclear ribonucleoprotein antibodies in MRL/Mp-lpr/lpr mice suggests that the intact U1 snRNP particle is their autoimmunogenic target. Journal Of Immunology (Baltimore, Md. : 1950) 1994, 152: 5523-31. PMID: 7514640.
- Immunoglobulin synthesis and generalized autoimmunity in mice congenitally deficient in αβ(+) T cellsWen L, Roberts S, Viney J, Wong F, Mallick C, Findly R, Peng Q, Craft J, Owen M, Mayday A. Immunoglobulin synthesis and generalized autoimmunity in mice congenitally deficient in αβ(+) T cells Nature 1994, 369: 654-658. PMID: 8208291, DOI: 10.1038/369654a0.
- B cells process and present lupus autoantigens that initiate autoimmune T cell responses.Mamula MJ, Fatenejad S, Craft J. B cells process and present lupus autoantigens that initiate autoimmune T cell responses. The Journal Of Immunology 1994, 152: 1453-61. PMID: 8301145, DOI: 10.4049/jimmunol.152.3.1453.
- Role of intermolecular/intrastructural B- and T-cell determinants in the diversification of autoantibodies to ribonucleoprotein particles.Fatenejad S, Mamula MJ, Craft J. Role of intermolecular/intrastructural B- and T-cell determinants in the diversification of autoantibodies to ribonucleoprotein particles. Proceedings Of The National Academy Of Sciences Of The United States Of America 1993, 90: 12010-12014. PMID: 8265662, PMCID: PMC48115, DOI: 10.1073/pnas.90.24.12010.
- Nucleotide sequence analysis of the A protein of the U1 small nuclear ribonucleoprotein particle: the murine protein contains a 5' amino-terminal tag.Bennett MM, Baron MA, Craft J. Nucleotide sequence analysis of the A protein of the U1 small nuclear ribonucleoprotein particle: the murine protein contains a 5' amino-terminal tag. Nucleic Acids Research 1993, 21: 4404. PMID: 8415008, PMCID: PMC310090, DOI: 10.1093/nar/21.18.4404.
- Identification of autoantibodies to RNA polymerase II. Occurrence in systemic sclerosis and association with autoantibodies to RNA polymerases I and III.Hirakata M, Okano Y, Pati U, Suwa A, Medsger TA, Hardin JA, Craft J. Identification of autoantibodies to RNA polymerase II. Occurrence in systemic sclerosis and association with autoantibodies to RNA polymerases I and III. The Journal Of Clinical Investigation 1993, 91: 2665-72. PMID: 8390487, PMCID: PMC443330, DOI: 10.1172/JCI116505.
- Autoantigenic epitopes of the B and D polypeptides of the U1 snRNP. Analysis of domains recognized by the Y12 monoclonal anti-Sm antibody and by patient sera.Hirakata M, Craft J, Hardin JA. Autoantigenic epitopes of the B and D polypeptides of the U1 snRNP. Analysis of domains recognized by the Y12 monoclonal anti-Sm antibody and by patient sera. Journal Of Immunology (Baltimore, Md. : 1950) 1993, 150: 3592-601. PMID: 7682245.
- Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks.Blier PR, Griffith AJ, Craft J, Hardin JA. Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks. The Journal Of Biological Chemistry 1993, 268: 7594-601. PMID: 8463290.
- Comparison of the Drosophila melanogaster, human and murine Sm B cDNAs: evolutionary conservation.Brunet C, Quan T, Craft J. Comparison of the Drosophila melanogaster, human and murine Sm B cDNAs: evolutionary conservation. Gene 1993, 124: 269-73. PMID: 7680326, DOI: 10.1016/0378-1119(93)90404-q.
- Prevention of Lyme Disease after Tick BitesMagid D, Schwartz B, Craft J, Schwartz J. Prevention of Lyme Disease after Tick Bites New England Journal Of Medicine 1992, 327: 534-541. PMID: 1298217, DOI: 10.1056/nejm199208203270806.
- Autoantigenic epitopes of the B polypeptide of Sm small nuclear RNP particles. Identification of regions accessible only within the U1 small nuclear RNP.Ohosone Y, Mimori T, Fujii T, Akizuki M, Matsuoka Y, Irimajiri S, Hardin JA, Craft J, Homma M. Autoantigenic epitopes of the B polypeptide of Sm small nuclear RNP particles. Identification of regions accessible only within the U1 small nuclear RNP. Arthritis And Rheumatism 1992, 35: 960-6. PMID: 1379432, DOI: 10.1002/art.1780350818.
- The murine gene encoding the highly conserved Sm B protein contains a nonfunctional alternative 3' splice site.Griffith AJ, Schmauss C, Craft J. The murine gene encoding the highly conserved Sm B protein contains a nonfunctional alternative 3' splice site. Gene 1992, 114: 195-201. PMID: 1376292, DOI: 10.1016/0378-1119(92)90574-9.
- Nucleotide sequence and genomic structure analyses of the p70 subunit of the human Ku autoantigen: evidence for a family of genes encoding Ku (p70)-related polypeptides.Griffith AJ, Craft J, Evans J, Mimori T, Hardin JA. Nucleotide sequence and genomic structure analyses of the p70 subunit of the human Ku autoantigen: evidence for a family of genes encoding Ku (p70)-related polypeptides. Molecular Biology Reports 1992, 16: 91-7. PMID: 1608402, DOI: 10.1007/BF00419754.
- Antibodies to snRNPs in systemic lupus erythematosus.Craft J. Antibodies to snRNPs in systemic lupus erythematosus. Rheumatic Diseases Clinics Of North America 1992, 18: 311-35. PMID: 1626072.
- Autoantibodies to small nuclear and cytoplasmic ribonucleoproteins in Japanese patients with inflammatory muscle disease.Hirakata M, Mimori T, Akizuki M, Craft J, Hardin JA, Homma M. Autoantibodies to small nuclear and cytoplasmic ribonucleoproteins in Japanese patients with inflammatory muscle disease. Arthritis And Rheumatism 1992, 35: 449-56. PMID: 1567494, DOI: 10.1002/art.1780350415.
- PBC 95k, a 95-kilodalton nuclear autoantigen in primary biliary cirrhosis.Evans J, Reuben A, Craft J. PBC 95k, a 95-kilodalton nuclear autoantigen in primary biliary cirrhosis. Arthritis And Rheumatism 1991, 34: 731-6. PMID: 2053918, DOI: 10.1002/art.1780340614.
- The analysis of antinuclear and antinucleolar autoantibodies of scleroderma by radioimmunoprecipitation assays.Kipnis RJ, Craft J, Hardin JA. The analysis of antinuclear and antinucleolar autoantibodies of scleroderma by radioimmunoprecipitation assays. Arthritis And Rheumatism 1990, 33: 1431-7. PMID: 2403405, DOI: 10.1002/art.1780330917.
- Lyme disease.Rahn DW, Craft J. Lyme disease. Rheumatic Diseases Clinics Of North America 1990, 16: 601-15. PMID: 2217960.
- Human Ro ribonucleoprotein particles: characterization of native structure and stable association with the La polypeptide.Boire G, Craft J. Human Ro ribonucleoprotein particles: characterization of native structure and stable association with the La polypeptide. Journal Of Clinical Investigation 1990, 85: 1182-1190. PMID: 1690756, PMCID: PMC296550, DOI: 10.1172/jci114551.
- snRNPs and scRNPs as autoantigens: clues to the etiology of the connective tissue diseasesCraft J, Mamula M, Ohosone Y, Boire G, Gold H, Hardin J. snRNPs and scRNPs as autoantigens: clues to the etiology of the connective tissue diseases Clinical Rheumatology 1990, 9: 10-19. PMID: 1697517, DOI: 10.1007/bf02205547.
- The Th ribonucleoprotein particle: association with the RNA processing enzymes RNase MRP and RNase P.Craft J, Gold H. The Th ribonucleoprotein particle: association with the RNA processing enzymes RNase MRP and RNase P. Molecular Biology Reports 1990, 14: 109. PMID: 1694555, DOI: 10.1007/BF00360435.
- New RNPs of higher eukaryotes.Craft J, Gold H. New RNPs of higher eukaryotes. Molecular Biology Reports 1990, 14: 97-101. PMID: 2194112, DOI: 10.1007/BF00360432.
- An immunological determinant of RNase P protein is conserved between Escherichia coli and humans.Mamula MJ, Baer M, Craft J, Altman S. An immunological determinant of RNase P protein is conserved between Escherichia coli and humans. Proceedings Of The National Academy Of Sciences Of The United States Of America 1989, 86: 8717-8721. PMID: 2479027, PMCID: PMC298359, DOI: 10.1073/pnas.86.22.8717.
- The RNA processing enzyme RNase MRP is identical to the Th RNP and related to RNase P.Gold HA, Topper JN, Clayton DA, Craft J. The RNA processing enzyme RNase MRP is identical to the Th RNP and related to RNase P. Science (New York, N.Y.) 1989, 245: 1377-80. PMID: 2476849, DOI: 10.1126/science.2476849.
- Higher order structure is present in the yeast nucleus: autoantibody probes demonstrate that the nucleolus lies opposite the spindle pole body.Yang CH, Lambie EJ, Hardin J, Craft J, Snyder M. Higher order structure is present in the yeast nucleus: autoantibody probes demonstrate that the nucleolus lies opposite the spindle pole body. Chromosoma 1989, 98: 123-8. PMID: 2673672, DOI: 10.1007/BF00291048.
- Biochemical and immunological heterogeneity of the Ro ribonucleoprotein particles. Analysis with sera specific for the RohY5 particle.Boire G, Craft J. Biochemical and immunological heterogeneity of the Ro ribonucleoprotein particles. Analysis with sera specific for the RohY5 particle. Journal Of Clinical Investigation 1989, 84: 270-279. PMID: 2472427, PMCID: PMC303979, DOI: 10.1172/jci114150.
- Molecular cloning of cDNA encoding Sm autoantigen: derivation of a cDNA for a B polypeptide of the U series of small nuclear ribonucleoprotein particles.Ohosone Y, Mimori T, Griffith A, Akizuki M, Homma M, Craft J, Hardin JA. Molecular cloning of cDNA encoding Sm autoantigen: derivation of a cDNA for a B polypeptide of the U series of small nuclear ribonucleoprotein particles. Proceedings Of The National Academy Of Sciences Of The United States Of America 1989, 86: 4249-4253. PMID: 2524838, PMCID: PMC287428, DOI: 10.1073/pnas.86.11.4249.
- Clinical manifestations of Lyme disease in the United States.Trock DH, Craft JE, Rahn DW. Clinical manifestations of Lyme disease in the United States. Connecticut Medicine 1989, 53: 327-30. PMID: 2667885.
- Antibodies in human serum that precipitate ribonuclease P.Gold HA, Craft J, Hardin JA, Bartkiewicz M, Altman S. Antibodies in human serum that precipitate ribonuclease P. Proceedings Of The National Academy Of Sciences Of The United States Of America 1988, 85: 5483-5487. PMID: 2456570, PMCID: PMC281781, DOI: 10.1073/pnas.85.15.5483.
- Murine graft vs host disease. A model for study of mechanisms that generate autoantibodies to ribonucleoproteins.Gelpi C, Rodriguez-Sanchez JL, Martinez MA, Craft J, Hardin JA. Murine graft vs host disease. A model for study of mechanisms that generate autoantibodies to ribonucleoproteins. The Journal Of Immunology 1988, 140: 4160-6. PMID: 3372998, DOI: 10.4049/jimmunol.140.12.4160.
- The U2 small nuclear ribonucleoprotein particle as an autoantigen. Analysis with sera from patients with overlap syndromes.Craft J, Mimori T, Olsen TL, Hardin JA. The U2 small nuclear ribonucleoprotein particle as an autoantigen. Analysis with sera from patients with overlap syndromes. Journal Of Clinical Investigation 1988, 81: 1716-1724. PMID: 2968364, PMCID: PMC442616, DOI: 10.1172/jci113511.
- Autoantigenic histone epitopes: a comparison between procainamide- and hydralazine-induced lupus.Craft JE, Radding JA, Harding MW, Bernstein RM, Hardin JA. Autoantigenic histone epitopes: a comparison between procainamide- and hydralazine-induced lupus. Arthritis And Rheumatism 1987, 30: 689-94. PMID: 2440452, DOI: 10.1002/art.1780300612.
- Linked sets of antinuclear antibodies: what do they mean?Craft JE, Hardin JA. Linked sets of antinuclear antibodies: what do they mean? Journal Of Rheumatology Supplement 1987, 14 Suppl 13: 106-9. PMID: 2441041.
- A human IgM M-protein in a patient with unknown bleeding disorder binds to β-galactosyl and β-glucosyl residuesKusunoki S, Craft J, Roach B, Hardin J, Yu R. A human IgM M-protein in a patient with unknown bleeding disorder binds to β-galactosyl and β-glucosyl residues Archives Of Biochemistry And Biophysics 1987, 255: 226-232. PMID: 3592674, DOI: 10.1016/0003-9861(87)90389-4.
- Patterns of Autoimmunity to Nucleoproteins in Patients with Systemic Lupus ErythematosusHardin J, Craft J. Patterns of Autoimmunity to Nucleoproteins in Patients with Systemic Lupus Erythematosus Rheumatic Disease Clinics Of North America 1987, 13: 37-46. PMID: 3306823, DOI: 10.1016/s0889-857x(21)00820-6.
- Clinical manifestations of lyme diseaseSteere A, Bartenhagen N, Craft J, Hutchinson G, Newman J, Pachner A, Rahn D, Sigal L, Taylor E, Malawista S. Clinical manifestations of lyme disease International Journal Of Medical Microbiology 1986, 263: 201-205. PMID: 3554839, DOI: 10.1016/s0176-6724(86)80123-7.
- Antigens of Borrelia burgdorferi recognized during Lyme disease. Appearance of a new immunoglobulin M response and expansion of the immunoglobulin G response late in the illness.Craft JE, Fischer DK, Shimamoto GT, Steere AC. Antigens of Borrelia burgdorferi recognized during Lyme disease. Appearance of a new immunoglobulin M response and expansion of the immunoglobulin G response late in the illness. Journal Of Clinical Investigation 1986, 78: 934-939. PMID: 3531237, PMCID: PMC423723, DOI: 10.1172/jci112683.
- Antibody response in Lyme disease: evaluation of diagnostic tests.Craft JE, Grodzicki RL, Steere AC. Antibody response in Lyme disease: evaluation of diagnostic tests. The Journal Of Infectious Diseases 1984, 149: 789-95. PMID: 6373966, DOI: 10.1093/infdis/149.5.789.
- Recovery of Lyme disease spirochetes from patients.Steere AC, Grodzicki RL, Craft JE, Shrestha M, Kornblatt AN, Malawista SE. Recovery of Lyme disease spirochetes from patients. The Yale Journal Of Biology And Medicine 1984, 57: 557-60. PMID: 6393606, PMCID: PMC2589990.
- The antibody response in Lyme disease.Craft JE, Grodzicki RL, Shrestha M, Fischer DK, García-Blanco M, Steere AC. The antibody response in Lyme disease. The Yale Journal Of Biology And Medicine 1984, 57: 561-5. PMID: 6393607, PMCID: PMC2590019.
- Treatment of the early manifestations of Lyme disease.Steere AC, Hutchinson GJ, Rahn DW, Sigal LH, Craft JE, DeSanna ET, Malawista SE. Treatment of the early manifestations of Lyme disease. Annals Of Internal Medicine 1983, 99: 22-6. PMID: 6407378, DOI: 10.7326/0003-4819-99-1-22.
- The early clinical manifestations of Lyme disease.Steere AC, Bartenhagen NH, Craft JE, Hutchinson GJ, Newman JH, Rahn DW, Sigal LH, Spieler PN, Stenn KS, Malawista SE. The early clinical manifestations of Lyme disease. Annals Of Internal Medicine 1983, 99: 76-82. PMID: 6859726, DOI: 10.7326/0003-4819-99-1-76.
- Clinical findings in Southeast Asian refugees.Barry M, Craft J, Coleman D, Coulter HO, Horwitz R. Clinical findings in Southeast Asian refugees. JAMA 1983, 249: 3200-3. PMID: 6854849.
- Hematologic abnormalities in Southeast Asian refugees.Craft J, Coleman D, Coulter HO, Horwitz R, Barry M. Hematologic abnormalities in Southeast Asian refugees. JAMA 1983, 249: 3204-6. PMID: 6854850.
- The Spirochetal Etiology of Lyme DiseaseSteere A, Grodzicki R, Kornblatt A, Craft J, Barbour A, Burgdorfer W, Schmid G, Johnson E, Malawista S. The Spirochetal Etiology of Lyme Disease New England Journal Of Medicine 1983, 308: 733-740. PMID: 6828118, DOI: 10.1056/nejm198303313081301.
- Ultrastructural description of a "cylinder organelle" in the outer plexiform layer of human retinas.Craft J, Albert DM, Reid TW. Ultrastructural description of a "cylinder organelle" in the outer plexiform layer of human retinas. Investigative Ophthalmology 1975, 14: 923-7. PMID: 1193806.
Clinical Trials
Conditions | Study Title |
---|---|
Immune System | Yale Lupus and Connective Tissue Disease Bio-Repository / Yale Rheumatology Bio-Repository |
Diseases of the Nervous System; Mental Health & Behavioral Research | Teen Brain and Behavior Study |