Publications

2026

α2-Adrenergic receptor modulates 5-HT2A-mediated behavioral effects of MDMA and psilocybin in mice
Rosado A, Yu A, Yang J, Rondeau J, Floris G, Basu A, Staszko S, Dibbs M, Feng J, Li Y, Warner-Schmidt J, Kelmendi B, Krystal J, Pittenger C, Kwan A, Kaye A. α2-Adrenergic receptor modulates 5-HT2A-mediated behavioral effects of MDMA and psilocybin in mice. Molecular Psychiatry 2026, 1-12. PMID: 42414551, DOI: 10.1038/s41380-026-03713-1.
Peer-Reviewed Original Research
Artificial intelligence as an adjunctive tool for rater qualification for clinical trials: an illustration
Targum S, Newton S, DeBonis D, Wilkinson S, Sanacora G. Artificial intelligence as an adjunctive tool for rater qualification for clinical trials: an illustration. Journal Of Affective Disorders Reports 2026, 25: 101068. DOI: 10.1016/j.jadr.2026.101068.
Peer-Reviewed Original Research
A genomic study of trichotillomania and excoriation disorder in families
Greenspun S, Milanes I, Farhat L, Abdallah S, Bok D, Chen D, Liu W, Teefe E, Bloch M, Fernandez T, Olfson E. A genomic study of trichotillomania and excoriation disorder in families. Translational Psychiatry 2026 PMID: 42315517, DOI: 10.1038/s41398-026-04164-6.
Peer-Reviewed Original Research
Using connectome-based predictive models to reveal the systems standardized tests and clinical symptoms are reflecting
Samardzija A, Shen X, Luo W, Greene A, Mehta S, Tokoglu F, Arora J, Woods S, Katz R, Sanacora G, Srihari V, Scheinost D, Constable R. Using connectome-based predictive models to reveal the systems standardized tests and clinical symptoms are reflecting. Nature Communications 2026 PMID: 42303975, DOI: 10.1038/s41467-026-73941-0.
Peer-Reviewed Original Research
Monitoring of Clinics That Use Direct‐to‐Consumer Advertising for Off‐Label Ketamine in the New York Metropolitan Area: A Cross‐Sectional Systematic Web Search
Abukahok N, Lawrence S, Adhikari S, Wilkinson S, Palamar J. Monitoring of Clinics That Use Direct‐to‐Consumer Advertising for Off‐Label Ketamine in the New York Metropolitan Area: A Cross‐Sectional Systematic Web Search. Fundamental & Clinical Pharmacology 2026, 40: e70095. PMID: 42274347, PMCID: PMC13262787, DOI: 10.1111/fcp.70095.
Peer-Reviewed Original Research
MeSH Keywords
Reversible alterations of brain acetate metabolism associated with alcohol consumption
Kumaragamage C, Jiang L, Angarita G, de Graaf R, Guidone E, Coppoli A, Behar K, Gulanski B, Pittman B, Weinzimer S, Rothman D, Krystal J, Mason G. Reversible alterations of brain acetate metabolism associated with alcohol consumption. Neuropsychopharmacology 2026, 1-9. PMID: 42218273, DOI: 10.1038/s41386-026-02455-6.
Peer-Reviewed Original Research
Metabolic dysfunction-associated steatotic liver disease and neurocognitive and reward circuit dysfunction: implications for mental disorders
Mollin N, Le G, Dri C, Yang E, van Bruggen F, Lin K, Bargiota S, Lo H, Ho R, Rhee T, Cao B, Kwan A, McIntyre R. Metabolic dysfunction-associated steatotic liver disease and neurocognitive and reward circuit dysfunction: implications for mental disorders. CNS Spectrums 2026, 31: e17. DOI: 10.1017/s1092852926100984.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
Ketamine Infusions and Rapid Reduction of Suicidal and Depressive Symptoms in Major Depressive Episode
Shim S, Jeong H, Bommersbach T, Nierenberg A, Zarate C, Kaster T, Correll C, McIntyre R, Krystal J, Rhee T. Ketamine Infusions and Rapid Reduction of Suicidal and Depressive Symptoms in Major Depressive Episode. JAMA Psychiatry 2026, 83 PMID: 42090166, PMCID: PMC13150733, DOI: 10.1001/jamapsychiatry.2026.0612.
Peer-Reviewed Original Research
Adjunctive Antipsychotics in Major Depressive Disorder
McIntyre R, Stahl S, Shim S, Pompili M, Goldberg J, Correll C, Kwan A, Dri C, Xu H, Vinberg M, Rhee T. Adjunctive Antipsychotics in Major Depressive Disorder. JAMA Psychiatry 2026, 83 PMID: 42090141, PMCID: PMC13150735, DOI: 10.1001/jamapsychiatry.2026.0658.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
Cognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention: The CBT-ENDURE Randomized Trial.
Wilkinson S, Kitay B, Macaluso M, Santucci M, Kumpf K, Voghell C, Astorino L, Hershenberg R, Martinez-Kaigi V, Nowell T, Thase M, Sanacora G, Rhee T. Cognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention: The CBT-ENDURE Randomized Trial. The Journal Of Clinical Psychiatry 2026, 87 PMID: 42095692, DOI: 10.4088/jcp.25m16285.
Peer-Reviewed Original Research
MeSH Keywords
Efficacy and Safety of the Neuroplastogen TSND-201 for the Treatment of PTSD
Jones A, Warner-Schmidt J, Kwak H, Stogniew M, Mandell B, Ching T, Stein M, Kelmendi B. Efficacy and Safety of the Neuroplastogen TSND-201 for the Treatment of PTSD. JAMA Psychiatry 2026, 83: 469-477. PMID: 41706459, PMCID: PMC12917749, DOI: 10.1001/jamapsychiatry.2025.4625.
Peer-Reviewed Original Research
This study investigates TSND-201, a rapid-acting neuroplastogen, showing significant, durable reductions in PTSD symptoms and good safety, supporting its potential as an effective treatment.
Full Summary
A Meta-Analysis of Drift-Diffusion Modeling of Self-Referential Processing and Relations with Depressive Symptoms
Edgar E, Ibrahim K, Bloch M, Crowley M. A Meta-Analysis of Drift-Diffusion Modeling of Self-Referential Processing and Relations with Depressive Symptoms. Computational Brain & Behavior 2026, 1-18. DOI: 10.1007/s42113-026-00283-x.
Peer-Reviewed Original Research
Concurrent SSRI, SNRI, or Other Antidepressant Use Not Associated With Differential Outcomes in Ketamine or Esketamine Treatment.
Curran E, Hardy M, Katz R, Rhee T, Wilkinson S. Concurrent SSRI, SNRI, or Other Antidepressant Use Not Associated With Differential Outcomes in Ketamine or Esketamine Treatment. The Journal Of Clinical Psychiatry 2026, 87 PMID: 42095696, DOI: 10.4088/jcp.25br16294.
Peer-Reviewed Original Research
Lower synaptic density in mood circuitry underlies depression in Parkinson’s disease
Cayir S, Naganawa M, Volpi T, Sadabad F, Dias M, Yang Y, Elliott S, Ansari M, Elshahat A, Pittman B, Esterlis I, Nabulsi N, Huang Y, Sanacora G, Comley R, Finnema S, Carson R, Tinaz S, Matuskey D, Holmes S. Lower synaptic density in mood circuitry underlies depression in Parkinson’s disease. Brain Communications 2026, 8: fcag136. PMID: 42109687, PMCID: PMC13152014, DOI: 10.1093/braincomms/fcag136.
Peer-Reviewed Original Research
Electroconvulsive therapy: improved understanding of long-term risks and benefits from advances in administrative health data
Kaster T, Rhee T, Adler E, Kirov G. Electroconvulsive therapy: improved understanding of long-term risks and benefits from advances in administrative health data. The British Journal Of Psychiatry 2026, 1-6. PMID: 41986911, PMCID: PMC13173538, DOI: 10.1192/bjp.2026.10613.
Peer-Reviewed Original Research
Optimized reference region and the effect on test-retest reliability and sensitivity to differences between Parkinson’s disease and control groups with [11C]UCB-J
Khattar N, Matuskey D, Gallezot J, Naganawa M, Holmes S, Sadabad F, Mayeli M, Esterlis I, van Dyck C, Mecca A, D’Souza D, Nabulsi N, Finnema S, Huang Y, Carson R, Toyonaga T. Optimized reference region and the effect on test-retest reliability and sensitivity to differences between Parkinson’s disease and control groups with [11C]UCB-J. Journal Of Cerebral Blood Flow And Metabolism : Official Journal Of The International Society Of Cerebral Blood Flow And Metabolism 2026, 0271678x261441071. PMID: 41960765, PMCID: PMC13068773, DOI: 10.1177/0271678x261441071.
Peer-Reviewed Original Research
Insufficient Sleep Among US Adolescents Across Behavioral Risk Groups
Bommersbach T, Olfson M, Rhee T. Insufficient Sleep Among US Adolescents Across Behavioral Risk Groups. JAMA: The Journal Of The American Medical Association 2026, 335: 1173-1176. PMID: 41770537, PMCID: PMC12954592, DOI: 10.1001/jama.2026.1417.
Peer-Reviewed Original Research
Effect of Esketamine on Depressive Symptoms in Adolescents With Major Depressive Disorder at Imminent Suicide Risk: A Randomized Psychoactive-Controlled Study
Kosik-Gonzalez C, Fu D, Chen L, Lane R, Bloch M, DelBello M, Moreno C, Drevets W, Canuso C. Effect of Esketamine on Depressive Symptoms in Adolescents With Major Depressive Disorder at Imminent Suicide Risk: A Randomized Psychoactive-Controlled Study. FOCUS The Journal Of Lifelong Learning In Psychiatry 2026, 24: 223-235. DOI: 10.1176/appi.focus.26024113.
Peer-Reviewed Original Research
Long-Term Safety and Maintenance of Response With Esketamine Nasal Spray in Participants With Treatment-Resistant Depression: Interim Results of the SUSTAIN-3 Study
Zaki N, Chen L, Lane R, Doherty T, Drevets W, Morrison R, Sanacora G, Wilkinson S, Popova V, Fu D. Long-Term Safety and Maintenance of Response With Esketamine Nasal Spray in Participants With Treatment-Resistant Depression: Interim Results of the SUSTAIN-3 Study. FOCUS The Journal Of Lifelong Learning In Psychiatry 2026, 24: 212-222. DOI: 10.1176/appi.focus.26024111.
Peer-Reviewed Original Research
Trajectories of late-life depression: insights from molecular imaging
Holmes S, Smith G. Trajectories of late-life depression: insights from molecular imaging. Neuropsychopharmacology 2026, 1-19. PMID: 41922490, DOI: 10.1038/s41386-026-02340-2.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
Clinical effects of ursodeoxycholic acid in COVID-19 infection: a systematic review and dose–response meta-analysis
Song J, Shim S, Shin J, Choe W, Park J, Lee T, Kang S, Rhee T, Huh K. Clinical effects of ursodeoxycholic acid in COVID-19 infection: a systematic review and dose–response meta-analysis. Frontiers In Pharmacology 2026, 17: 1719144. PMID: 41993579, PMCID: PMC13079291, DOI: 10.3389/fphar.2026.1719144.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
Calculating and extracting missing summary statistics for meta-analysis
Shin J, Rhee T, Kim S, Shim S. Calculating and extracting missing summary statistics for meta-analysis. Journal Of Evidence-Based Practice 2026, 2: 1-7. DOI: 10.63528/jebp.2026.00002.
Peer-Reviewed Original Research
Medically Recommended Cannabis Use for U.S. Adolescents
Bommersbach T, Olfson M, Rhee T. Medically Recommended Cannabis Use for U.S. Adolescents. American Journal Of Preventive Medicine 2026, 71: 108355. PMID: 41903661, DOI: 10.1016/j.amepre.2026.108355.
Peer-Reviewed Original Research
Influence of self-referential processing on depression and anxiety: A meta-analysis of cognitive biases and task variants
Edgar E, Reid L, Marco L, Sawada Y, Ibrahim K, Bloch M, Crowley M. Influence of self-referential processing on depression and anxiety: A meta-analysis of cognitive biases and task variants. Journal Of Psychiatric Research 2026, 198: 240-251. PMID: 41931984, PMCID: PMC13176957, DOI: 10.1016/j.jpsychires.2026.03.035.
Peer-Reviewed Original Research
MeSH Keywords
The American Society of Clinical Psychopharmacology (ASCP) task force on the deprescribing of psychotropic medications for mood disorders: Delphi expert consensus.
Goldberg J, Swartz H, McIntyre R, Mago R, Malhi G, Jha M, Berk M, Kasper S, Freeman M, Gitlin M, Sajatovic M, Ostacher M, Citrome L, Iosifescu D, Perlis R, Furukawa T, Vieta E, Thase M, Young A, Tohen M, Nierenberg A, Macaluso M, Shelton R, Correll C, Aaronson S, Rosenblat J, Gorwood P, Khan A, Kupka R, Cohen L, Mitchell P, Frye M, Sanacora G, Kane J, Rubio-Lorente J, Goodman D, Zohar J, Davis L, Gupta S, Steingard S, Zarate C, Clayton A. The American Society of Clinical Psychopharmacology (ASCP) task force on the deprescribing of psychotropic medications for mood disorders: Delphi expert consensus. The British Journal Of Psychiatry 2026, 1-9. PMID: 41877318, DOI: 10.1192/bjp.2026.10580.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements

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