Publications

2026

Correlates of Impaired Sleep Duration Among Adults With Trauma Alone and With Posttraumatic Stress Disorder
Havlik J, Rhee T, Rosenheck R. Correlates of Impaired Sleep Duration Among Adults With Trauma Alone and With Posttraumatic Stress Disorder. Psychological Trauma Theory Research Practice And Policy 2026, 18: 1544-1553. PMID: 39836166, DOI: 10.1037/tra0001846.
Peer-Reviewed Original Research
NMDA subunit 2B-selective negative allosteric modulator satoprodil (BI 1569912) as mono- and adjunctive therapy in patients with major depressive disorder: results from two phase 2 randomized, controlled trials
Cohen E, Sanacora G, Watanabe K, Feldbarg A, Goeldner R, Scholz A, Starling B, Süssmuth S, Fowler J, De Crescenzo F. NMDA subunit 2B-selective negative allosteric modulator satoprodil (BI 1569912) as mono- and adjunctive therapy in patients with major depressive disorder: results from two phase 2 randomized, controlled trials. Neuropsychopharmacology 2026, 1-13. PMID: 42701110, DOI: 10.1038/s41386-026-02538-4.
Peer-Reviewed Original Research
Supervised machine learning enables identification of people with untreated substance use disorders using EHR-like data
Havlik J, Murphy M, Rhee T, Humphreys K, Rosenheck R. Supervised machine learning enables identification of people with untreated substance use disorders using EHR-like data. Nature Mental Health 2026, 1-13. DOI: 10.1038/s44220-026-00717-2.
Peer-Reviewed Original Research
The Randomization Effect in a Double-Blind Placebo-Controlled Depression Study.
Targum S, Ceesay P, Lines C, Thase M, Sanacora G, Merola A. The Randomization Effect in a Double-Blind Placebo-Controlled Depression Study. Journal Of Clinical Psychopharmacology 2026 PMID: 42684061, DOI: 10.1097/jcp.0000000000002250.
Peer-Reviewed Original Research
Comment on Esketamine 5 Years After Approval: Welcome New Data With Continuing Questions
Ahmed M, Cabrera P, Doherty T, Himedan M, Kern D, Turkoz I, Sanacora G. Comment on Esketamine 5 Years After Approval: Welcome New Data With Continuing Questions. American Journal Of Psychiatry 2026, 183: 682-683. PMID: 41844563, DOI: 10.1176/appi.ajp.20251203.
Commentaries, Editorials and Letters
Surrender, disidentification, and reappraisal: a qualitative comparison of psilocybin responders and non-responders in treatment-resistant OCD
Agin-Liebes G, Shnayder S, Fram G, Swift T, Ching T, Jankovsky A, Hokanson J, Pittenger C, Kelmendi B. Surrender, disidentification, and reappraisal: a qualitative comparison of psilocybin responders and non-responders in treatment-resistant OCD. Frontiers In Psychiatry 2026, 17: 1791689. PMID: 42746496, PMCID: PMC13576466, DOI: 10.3389/fpsyt.2026.1791689.
Peer-Reviewed Original Research
Whole-exome sequencing in individuals with obsessive–compulsive disorder and chronic tic disorders identifies 36 large-effect risk genes
Wang B, Tran M, Wang S, Liu Y, Olfson E, Wang G, Sun N, Dea J, Olwal C, Bertolace L, Bloch M, Cappi C, Chang Y, Chavira D, Coffey B, Falkenstein M, Frank A, Franklin M, Garayalde S, Garrido H, Grados M, Hatem R, Howell A, Khim S, Kuckertz J, Le M, Libby A, McCarty R, McNamara M, McNeil D, Miguel E, Nasello C, Nguyen B, Norbu T, Oh L, Ordway A, Paciotti C, Peskin V, Pittenger C, Simpson H, Simpson Martin H, Tischfield M, Xing J, Zakrzewski J, Dietrich A, Gilbert D, Hoekstra P, Kim Y, Kuperman S, Rosen A, Zinner S, Bouhaddou M, King R, Rouleau G, Ressler K, Mathews C, Krogan N, Sestan N, Tischfield J, Lee A, Heiman G, Fernandez T, Willsey A. Whole-exome sequencing in individuals with obsessive–compulsive disorder and chronic tic disorders identifies 36 large-effect risk genes. Nature Neuroscience 2026, 1-13. PMID: 42680906, DOI: 10.1038/s41593-026-02419-5.
Peer-Reviewed Original Research
Transdiagnostic connectome-based predictive modeling reveals networks jointly linked to subjective clinical symptoms and cognition
Simon A, Samardzija A, Iannone S, Parra F, Mehta S, Tokoglu F, Qiu M, Arora J, Tang K, Flanagan A, Katz R, Sanacora G, Woods S, Srihari V, Shen X, Scheinost D, Constable R. Transdiagnostic connectome-based predictive modeling reveals networks jointly linked to subjective clinical symptoms and cognition. Communications Biology 2026 DOI: 10.1038/s42003-026-10822-8.
Peer-Reviewed Original Research
Next-Generation Pharmacotherapies for Unipolar Mood Disorders: A Leading Article on Phase II/III Drug Development Across Diverse Mechanisms
King A, Hardy M, Rhee T, Wilkinson S. Next-Generation Pharmacotherapies for Unipolar Mood Disorders: A Leading Article on Phase II/III Drug Development Across Diverse Mechanisms. CNS Drugs 2026, 1-16. PMID: 42645703, DOI: 10.1007/s40263-026-01330-8.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
A Systematic Review of Long-term Safety Outcomes of Ketamine and Esketamine in Patients with Treatment-resistant Depression.
Wasolua T, Hardy M, Bommersbach T, McIntyre R, Rhee T. A Systematic Review of Long-term Safety Outcomes of Ketamine and Esketamine in Patients with Treatment-resistant Depression. Psychotherapy And Psychosomatics 2026, 1. PMID: 42611840, DOI: 10.1159/pps/aemag005.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
Association between dextromethorphan/bupropion with diabetes mellitus and hyperglycemia: reports to the Food and Drug Administration Adverse Event Reporting System (FAERS)
Zheng Y, Wong S, Le G, Kwan A, Dri C, Ho R, Rhee T, Guillen-Burgos H, McIntyre R. Association between dextromethorphan/bupropion with diabetes mellitus and hyperglycemia: reports to the Food and Drug Administration Adverse Event Reporting System (FAERS). CNS Spectrums 2026, 31: e36. PMID: 42563435, DOI: 10.1017/s1092852926101163.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
MeSH Keywords
Associations between state-level prenatal substance use policies and treatment completion among pregnant women admitted to substance use treatment facilities
Chu J, Carandang R, Rhee T, Cunningham S. Associations between state-level prenatal substance use policies and treatment completion among pregnant women admitted to substance use treatment facilities. Journal Of Substance Use And Addiction Treatment 2026, 191: 210069. PMID: 42532382, DOI: 10.1016/j.josat.2026.210069.
Peer-Reviewed Original Research
Insufficient Sleep Among US Adolescents-Reply.
Bommersbach T, Olfson M, Rhee T. Insufficient Sleep Among US Adolescents-Reply. JAMA: The Journal Of The American Medical Association 2026, 336: 344-345. PMID: 42340703, DOI: 10.1001/jama.2026.6656.
Commentaries, Editorials and Letters
Health risk assessment of inorganic arsenic: an umbrella review
Leem S, Shin J, Lee J, Seo M, Zee S, Lee S, Kim J, Kim J, Rhee T, Shim S. Health risk assessment of inorganic arsenic: an umbrella review. Reviews On Environmental Health 2026, 41: 433-446. PMID: 42494104, DOI: 10.1515/reveh-2025-0124.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
MeSH Keywords
Combined Ketamine and Cognitive-Behavioral Therapy: Leveraging Metaplasticity to Enhance Treatment Outcomes
Hardy M, Li S, Wilkinson S. Combined Ketamine and Cognitive-Behavioral Therapy: Leveraging Metaplasticity to Enhance Treatment Outcomes. FOCUS The Journal Of Lifelong Learning In Psychiatry 2026, 24: 294-306. PMID: 42576910, PMCID: PMC13449557, DOI: 10.1176/appi.focus.20260001.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
α2-Adrenergic receptor modulates 5-HT2A-mediated behavioral effects of MDMA and psilocybin in mice
Rosado A, Yu A, Yang J, Rondeau J, Floris G, Basu A, Staszko S, Dibbs M, Feng J, Li Y, Warner-Schmidt J, Kelmendi B, Krystal J, Pittenger C, Kwan A, Kaye A. α2-Adrenergic receptor modulates 5-HT2A-mediated behavioral effects of MDMA and psilocybin in mice. Molecular Psychiatry 2026, 1-12. PMID: 42414551, DOI: 10.1038/s41380-026-03713-1.
Peer-Reviewed Original Research
Ketamine Infusions and Rapid Reduction of Suicidal and Depressive Symptoms in Major Depressive Episode
Shim S, Jeong H, Bommersbach T, Nierenberg A, Zarate C, Kaster T, Correll C, McIntyre R, Krystal J, Rhee T. Ketamine Infusions and Rapid Reduction of Suicidal and Depressive Symptoms in Major Depressive Episode. JAMA Psychiatry 2026, 83: 714-731. PMID: 42090166, PMCID: PMC13150733, DOI: 10.1001/jamapsychiatry.2026.0612.
Peer-Reviewed Original Research
Artificial intelligence as an adjunctive tool for rater qualification for clinical trials: an illustration
Targum S, Newton S, DeBonis D, Wilkinson S, Sanacora G. Artificial intelligence as an adjunctive tool for rater qualification for clinical trials: an illustration. Journal Of Affective Disorders Reports 2026, 25: 101068. DOI: 10.1016/j.jadr.2026.101068.
Peer-Reviewed Original Research
Adjunctive Antipsychotics in Major Depressive Disorder
McIntyre R, Stahl S, Shim S, Pompili M, Goldberg J, Correll C, Kwan A, Dri C, Xu H, Vinberg M, Rhee T. Adjunctive Antipsychotics in Major Depressive Disorder. JAMA Psychiatry 2026, 83: 741-750. PMID: 42090141, PMCID: PMC13150735, DOI: 10.1001/jamapsychiatry.2026.0658.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
Editorial: Intergenerational Benefits of Treating Maternal Depression: Recognizing Externalities
Brady R, Bloch M. Editorial: Intergenerational Benefits of Treating Maternal Depression: Recognizing Externalities. Journal Of The American Academy Of Child And Adolescent Psychiatry 2026 PMID: 42379514, DOI: 10.1016/j.jaac.2026.06.019.
Commentaries, Editorials and Letters
A genomic study of trichotillomania and excoriation disorder in families
Greenspun S, Milanes I, Farhat L, Abdallah S, Bok D, Chen D, Liu W, Teefe E, Bloch M, Fernandez T, Olfson E. A genomic study of trichotillomania and excoriation disorder in families. Translational Psychiatry 2026, 16: 432. PMID: 42315517, PMCID: PMC13522538, DOI: 10.1038/s41398-026-04164-6.
Peer-Reviewed Original Research
Using connectome-based predictive models to reveal the systems standardized tests and clinical symptoms are reflecting
Samardzija A, Shen X, Luo W, Greene A, Mehta S, Tokoglu F, Arora J, Woods S, Katz R, Sanacora G, Srihari V, Scheinost D, Constable R. Using connectome-based predictive models to reveal the systems standardized tests and clinical symptoms are reflecting. Nature Communications 2026, 17: 7650. PMID: 42303975, PMCID: PMC13434263, DOI: 10.1038/s41467-026-73941-0.
Peer-Reviewed Original Research
Monitoring of Clinics That Use Direct‐to‐Consumer Advertising for Off‐Label Ketamine in the New York Metropolitan Area: A Cross‐Sectional Systematic Web Search
Abukahok N, Lawrence S, Adhikari S, Wilkinson S, Palamar J. Monitoring of Clinics That Use Direct‐to‐Consumer Advertising for Off‐Label Ketamine in the New York Metropolitan Area: A Cross‐Sectional Systematic Web Search. Fundamental & Clinical Pharmacology 2026, 40: e70095-e70095. PMID: 42274347, PMCID: PMC13262787, DOI: 10.1111/fcp.70095.
Peer-Reviewed Original Research
MeSH Keywords
Reversible alterations of brain acetate metabolism associated with alcohol consumption
Kumaragamage C, Angarita G, de Graaf R, Guidone E, Coppoli A, Behar K, Gulanski B, Pittman B, Weinzimer S, Rothman D, Krystal J, Mason G. Reversible alterations of brain acetate metabolism associated with alcohol consumption. Neuropsychopharmacology 2026, 51: 1758-1766. PMID: 42218273, PMCID: PMC13334440, DOI: 10.1038/s41386-026-02455-6.
Peer-Reviewed Original Research
Metabolic dysfunction-associated steatotic liver disease and neurocognitive and reward circuit dysfunction: implications for mental disorders
Mollin N, Le G, Dri C, Yang E, van Bruggen F, Lin K, Bargiota S, Lo H, Ho R, Rhee T, Cao B, Kwan A, McIntyre R. Metabolic dysfunction-associated steatotic liver disease and neurocognitive and reward circuit dysfunction: implications for mental disorders. CNS Spectrums 2026, 31: e17. DOI: 10.1017/s1092852926100984.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements

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