Morgan Hardy, MD, MPH
Instructor of PsychiatryCards
About
Titles
Instructor of Psychiatry
Biography
Dr. Hardy is a board-certified psychiatrist and researcher with the Yale Depression Research Program, working under the mentorship of Samuel Wilkinson and Gerard Sanacora. His research focuses on enhancing the effectiveness of ketamine and other emerging therapeutics for treatment of severe mood disorders. Dr. Hardy also works clinically in the Yale Interventional Psychiatry Service.
Prior to joining Yale in September 2025, he served as a staff psychiatrist in the United States Air Force, rising to the rank of Major. While stationed in the United Kingdom, he created and directed the Air Force's first ketamine and esketamine treatment program for service members and their families with severe depression and post-traumatic stress disorder (PTSD). He has a prior research background in mild traumatic brain injury/PTSD and multi-modal interventions for high-utilizer psychiatric patients.
Last Updated on September 24, 2025.
Appointments
Psychiatry
InstructorPrimary
Other Departments & Organizations
- Interventional Psychiatry Service
- Psychiatry
- Yale Medicine
- Yale New Haven Health System
Education & Training
- MD
- Duke University School of Medicine (2017)
- MPH
- University of North Carolina at Chapel Hill (2016)
Research
Publications
2026
Next-Generation Pharmacotherapies for Unipolar Mood Disorders: A Leading Article on Phase II/III Drug Development Across Diverse Mechanisms
King A, Hardy M, Rhee T, Wilkinson S. Next-Generation Pharmacotherapies for Unipolar Mood Disorders: A Leading Article on Phase II/III Drug Development Across Diverse Mechanisms. CNS Drugs 2026, 1-16. PMID: 42645703, DOI: 10.1007/s40263-026-01330-8.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsA Systematic Review of Long-term Safety Outcomes of Ketamine and Esketamine in Patients with Treatment-resistant Depression.
Wasolua T, Hardy M, Bommersbach T, McIntyre R, Rhee T. A Systematic Review of Long-term Safety Outcomes of Ketamine and Esketamine in Patients with Treatment-resistant Depression. Psychotherapy And Psychosomatics 2026, 1. PMID: 42611840, DOI: 10.1159/pps/aemag005.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCombined Ketamine and Cognitive-Behavioral Therapy: Leveraging Metaplasticity to Enhance Treatment Outcomes
Hardy M, Li S, Wilkinson S. Combined Ketamine and Cognitive-Behavioral Therapy: Leveraging Metaplasticity to Enhance Treatment Outcomes. FOCUS The Journal Of Lifelong Learning In Psychiatry 2026, 24: 294-306. PMID: 42576910, PMCID: PMC13449557, DOI: 10.1176/appi.focus.20260001.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConcurrent SSRI, SNRI, or Other Antidepressant Use Not Associated With Differential Outcomes in Ketamine or Esketamine Treatment.
Curran E, Hardy M, Katz R, Rhee T, Wilkinson S. Concurrent SSRI, SNRI, or Other Antidepressant Use Not Associated With Differential Outcomes in Ketamine or Esketamine Treatment. The Journal Of Clinical Psychiatry 2026, 87 PMID: 42095696, DOI: 10.4088/jcp.25br16294.Peer-Reviewed Original Research
2025
The Potential Role of Hypnotic Suggestion in Ketamine-Assisted Psychotherapy for Depression.
Hardy M. The Potential Role of Hypnotic Suggestion in Ketamine-Assisted Psychotherapy for Depression. The Primary Care Companion For CNS Disorders 2025, 27 PMID: 39919225, DOI: 10.4088/pcc.24cr03826.Peer-Reviewed Original Research
2021
Embedded Psychiatric Services in a Multidisciplinary Amyotrophic Lateral Sclerosis Clinic: An Assessment of Patient Needs and Perceptions
Hardy M, Castle C, Jackson C. Embedded Psychiatric Services in a Multidisciplinary Amyotrophic Lateral Sclerosis Clinic: An Assessment of Patient Needs and Perceptions. Journal Of Neuropsychiatry 2021, 34: 53-59. PMID: 34763523, DOI: 10.1176/appi.neuropsych.21040092.Peer-Reviewed Original ResearchPrevention of Hypoxia During Electroconvulsive Therapy
Hardy M, Faber R, Vazquez J, Klinger J. Prevention of Hypoxia During Electroconvulsive Therapy. Journal Of Ect 2021, 37: 148-149. PMID: 34294648, DOI: 10.1097/yct.0000000000000787.Peer-Reviewed Original Research
2020
A Case of Serotonin Syndrome in the Setting of Dextromethorphan-Based Cough Medicine, Tramadol, and Multiple Antidepressants.
Hardy M, Panikkar G. A Case of Serotonin Syndrome in the Setting of Dextromethorphan-Based Cough Medicine, Tramadol, and Multiple Antidepressants. The Primary Care Companion For CNS Disorders 2020, 22 PMID: 32141719, DOI: 10.4088/pcc.19l02518.Peer-Reviewed Original ResearchPatient Attribution of Posttraumatic Symptoms to Brain Injury Versus PTSD in Military-Related Mild TBI
Hardy M, Kennedy J, Cooper D. Patient Attribution of Posttraumatic Symptoms to Brain Injury Versus PTSD in Military-Related Mild TBI. Journal Of Neuropsychiatry 2020, 32: 252-258. PMID: 32054399, DOI: 10.1176/appi.neuropsych.19090202.Peer-Reviewed Original ResearchDifferences in Posttraumatic Stress Disorder, Depression, and Attribution of Symptoms in Service Members With Combat Versus Noncombat Mild Traumatic Brain Injury
Hardy M, Kennedy J, Reid M, Cooper D. Differences in Posttraumatic Stress Disorder, Depression, and Attribution of Symptoms in Service Members With Combat Versus Noncombat Mild Traumatic Brain Injury. Journal Of Head Trauma Rehabilitation 2020, 35: 37-45. PMID: 31033746, DOI: 10.1097/htr.0000000000000486.Peer-Reviewed Original Research