Mei Xue Dong, MD, PhD
Assistant Professor of Medicine (Rheumatology, Allergy & Immunology)
Research & Publications
Biography
News
Locations
Coauthors
Selected Publications
- Type I Interferon–Activated STAT4 Regulation of Follicular Helper T Cell–Dependent Cytokine and Immunoglobulin Production in LupusDong X, Antao OQ, Song W, Sanchez GM, Zembrzuski K, Koumpouras F, Lemenze A, Craft J, Weinstein JS. Type I Interferon–Activated STAT4 Regulation of Follicular Helper T Cell–Dependent Cytokine and Immunoglobulin Production in Lupus. Arthritis & Rheumatology 2021, 73: 478-489. PMID: 33512094, PMCID: PMC7914134, DOI: 10.1002/art.41532.
- Lack of a significant role of P-Rex1, a major regulator of macrophage Rac1 activation and chemotaxis, in atherogenesisWang Z, Dong X, Li Z, Smith JD, Wu D. Lack of a significant role of P-Rex1, a major regulator of macrophage Rac1 activation and chemotaxis, in atherogenesis. Prostaglandins And Other Lipid Mediators 2008, 87: 9-13. PMID: 18502673, PMCID: PMC3644862, DOI: 10.1016/j.prostaglandins.2008.04.001.
- Phospholipase C β3 deficiency leads to macrophage hypersensitivity to apoptotic induction and reduction of atherosclerosis in miceWang Z, Liu B, Wang P, Dong X, Fernandez-Hernando C, Li Z, Hla T, Li Z, Claffey K, Smith JD, Wu D. Phospholipase C β3 deficiency leads to macrophage hypersensitivity to apoptotic induction and reduction of atherosclerosis in mice. Journal Of Clinical Investigation 2007, 118: 195-204. PMID: 18079968, PMCID: PMC2129238, DOI: 10.1172/jci33139.
- Signaling requirements for translocation of P‐Rex1, a key Rac2 exchange factor involved in chemoattractant‐stimulated human neutrophil functionZhao T, Nalbant P, Hoshino M, Dong X, Wu D, Bokoch GM. Signaling requirements for translocation of P‐Rex1, a key Rac2 exchange factor involved in chemoattractant‐stimulated human neutrophil function. Journal Of Leukocyte Biology 2007, 81: 1127-1136. PMID: 17227822, DOI: 10.1189/jlb.0406251.
- Characterization and Application of a New Optical Probe for Membrane Lipid DomainsJin L, Millard AC, Wuskell JP, Dong X, Wu D, Clark HA, Loew LM. Characterization and Application of a New Optical Probe for Membrane Lipid Domains. Biophysical Journal 2006, 90: 2563-2575. PMID: 16415047, PMCID: PMC1403187, DOI: 10.1529/biophysj.105.072884.
- Methods for Studying Neutrophil ChemotaxisDong X, Wu D. Methods for Studying Neutrophil Chemotaxis. 2006, 406: 605-613. PMID: 16472691, DOI: 10.1016/s0076-6879(06)06047-2.
- P-Rex1 Is a Primary Rac2 Guanine Nucleotide Exchange Factor in Mouse NeutrophilsDong X, Mo Z, Bokoch G, Guo C, Li Z, Wu D. P-Rex1 Is a Primary Rac2 Guanine Nucleotide Exchange Factor in Mouse Neutrophils. Current Biology 2005, 15: 1874-1879. PMID: 16243036, DOI: 10.1016/j.cub.2005.09.014.
- Regulation of PTEN by Rho small GTPasesLi Z, Dong X, Wang Z, Liu W, Deng N, Ding Y, Tang L, Hla T, Zeng R, Li L, Wu D. Regulation of PTEN by Rho small GTPases. Nature Cell Biology 2005, 7: 399-404. PMID: 15793569, DOI: 10.1038/ncb1236.
Clinical Trials
| Conditions | Study Title |
|---|---|
| Immune System | Yale Lupus and Connective Tissue Disease Bio-Repository / Yale Rheumatology Bio-Repository |
| Arthritis | Yale Rheumatology Program Patient Registry and Bio-Repository |