Brenda Cabrera-Mendoza, MD/PhD
Postdoctoral Fellow
Research & Publications
Biography
News
Coauthors
Selected Publications
- Linking Behavior and Genetics: Psychopathology and Recognition of Anger and Other EmotionsCabrera-Mendoza B, Koller D, Polimanti R. Linking Behavior and Genetics: Psychopathology and Recognition of Anger and Other Emotions 2022, 1-19. DOI: 10.1007/978-3-030-98711-4_86-1.
- Within subject cross‐tissue analyzes of epigenetic clocks in substance use disorder postmortem brain and bloodCabrera‐Mendoza B, Stertz L, Najera K, Selvaraj S, Teixeira A, Meyer T, Fries G, Walss‐Bass C. Within subject cross‐tissue analyzes of epigenetic clocks in substance use disorder postmortem brain and blood American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2022, 192: 13-27. PMID: 36056652, PMCID: PMC9742183, DOI: 10.1002/ajmg.b.32920.
- The Relationship of Attention-Deficit/Hyperactivity Disorder With Posttraumatic Stress Disorder: A Two-Sample Mendelian Randomization and Population-Based Sibling Comparison StudyWendt FR, Garcia-Argibay M, Cabrera-Mendoza B, Valdimarsdóttir UA, Gelernter J, Stein MB, Nivard MG, Maihofer AX, Consortium P, Maihofer A, Choi K, Coleman J, Daskalakis N, Denckla C, Ketema E, Morey R, Polimanti R, Ratanatharathorn A, Torres K, Wingo A, Zai C, Aiello A, Almli L, Amstadter A, Andersen S, Andreassen O, Arbisi P, Ashley-Koch A, Austin S, Avdibegovic E, Borglum A, Babic D, Bækvad-Hansen M, Baker D, Beckham J, Bierut L, Bisson J, Boks M, Bolger E, Bradley B, Brashear M, Breen G, Bryant R, Bustamante A, Bybjerg-Grauholm J, Calabrese J, Caldas-de-Almeida J, Chen C, Dale A, Dalvie S, Deckert J, Delahanty D, Dennis M, Disner S, Domschke K, Duncan L, Kulenovic A, Erbes C, Evans A, Farrer L, Feeny N, Flory J, Forbes D, Franz C, Galea S, Garrett M, Gautam A, Gelaye B, Gelernter J, Geuze E, Gillespie C, Uka A, Gordon S, Guffanti G, Hammamieh R, Hauser M, Heath A, Hemmings S, Hougaard D, Jakovljevic M, Jett M, Johnson E, Jones I, Jovanovic T, Qin X, Karstoft K, Kaufman M, Kessler R, Khan A, Kimbrel N, King A, Koen N, Kranzler H, Kremen W, Lawford B, Lebois L, Lewis C, Liberzon I, Linnstaedt S, Logue M, Lori A, Lugonja B, Luykx J, Lyons M, Maples-Keller J, Marmar C, Martin N, Maurer D, Mavissakalian M, McFarlane A, McGlinchey R, McLaughlin K, McLean S, Mehta D, Mellor R, Michopoulos V, Milberg W, Miller M, Morris C, Mors O, Mortensen P, Nelson E, Nordentoft M, Norman S, O’Donnell M, Orcutt H, Panizzon M, Peters E, Peterson A, Peverill M, Pietrzak R, Polusny M, Rice J, Risbrough V, Roberts A, Rothbaum A, Rothbaum B, Roy-Byrne P, Ruggiero K, Rung A, Rutten B, Saccone N, Sanchez S, Schijven D, Seedat S, Seligowski A, Seng J, Sheerin C, Silove D, Smith A, Smoller J, Sponheim S, Stein D, Stevens J, Teicher M, Thompson W, Trapido E, Uddin M, Ursano R, van den Heuvel L, Van Hooff M, Vermetten E, Vinkers C, Voisey J, Wang Y, Wang Z, Werge T, Williams M, Williamson D, Winternitz S, Wolf C, Wolf E, Yehuda R, Young K, Young R, Zhao H, Zoellner L, Haas M, Lasseter H, Provost A, Salem R, Sebat J, Shaffer R, Wu T, Ripke S, Daly M, Ressler K, Koenen K, Stein M, Nievergelt C, Nievergelt C, Larsson H, Mattheisen M, Polimanti R, Meier S. The Relationship of Attention-Deficit/Hyperactivity Disorder With Posttraumatic Stress Disorder: A Two-Sample Mendelian Randomization and Population-Based Sibling Comparison Study Biological Psychiatry 2022, 93: 362-369. PMID: 36335070, DOI: 10.1016/j.biopsych.2022.08.012.
- The association of obesity-related traits on COVID-19 severity and hospitalization is affected by socio-economic status: a multivariable Mendelian randomization studyCabrera-Mendoza B, Wendt FR, Pathak GA, De Angelis F, De Lillo A, Koller D, Polimanti R. The association of obesity-related traits on COVID-19 severity and hospitalization is affected by socio-economic status: a multivariable Mendelian randomization study International Journal Of Epidemiology 2022, 51: 1371-1383. PMID: 35751636, PMCID: PMC9278255, DOI: 10.1093/ije/dyac129.
- High polygenic burden is associated with blood DNA methylation changes in individuals with suicidal behaviorCabrera-Mendoza B, Martínez-Magaña JJ, Genis-Mendoza AD, Sarmiento E, Ruíz-Ramos D, Tovilla-Zárate CA, González-Castro TB, Juárez-Rojop IE, García-de la Cruz DD, López-Armenta M, Real F, García-Dolores F, Flores G, Vázquez-Roque RA, Lanzagorta N, Escamilla M, Saucedo-Uribe E, Rodríguez-Mayoral O, Jiménez-Genchi J, Castañeda-González C, Roche-Bergua A, Nicolini H. High polygenic burden is associated with blood DNA methylation changes in individuals with suicidal behavior Journal Of Psychiatric Research 2020, 123: 62-71. PMID: 32036075, DOI: 10.1016/j.jpsychires.2020.01.008.
- Sex differences in brain gene expression among suicide completersCabrera-Mendoza B, Fresno C, Monroy-Jaramillo N, Fries GR, Walss-Bass C, Glahn DC, Ostrosky-Wegman P, Mendoza-Morales RC, García-Dolores F, Díaz-Otañez CE, González-Sáenz EE, Genis-Mendoza AD, Martínez-Magaña JJ, Romero-Pimentel AL, Flores G, Vázquez-Roque RA, Nicolini H. Sex differences in brain gene expression among suicide completers Journal Of Affective Disorders 2020, 267: 67-77. PMID: 32063575, DOI: 10.1016/j.jad.2020.01.167.
- Candidate pharmacological treatments for substance use disorder and suicide identified by gene co‐expression network‐based drug repositioningCabrera‐Mendoza B, Martínez‐Magaña J, Monroy‐Jaramillo N, Genis‐Mendoza A, Fresno C, Fries GR, Walss‐Bass C, Armenta M, García‐Dolores F, Díaz‐Otañez C, Flores G, Vázquez‐Roque R, Nicolini H. Candidate pharmacological treatments for substance use disorder and suicide identified by gene co‐expression network‐based drug repositioning American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2021, 186: 193-206. PMID: 33403748, DOI: 10.1002/ajmg.b.32830.
- Sex differences in the polygenic architecture of hearing problems in adultsDe Angelis, F., Zeleznik, O. A., Wendt, F. R., Pathak, G. A., Tylee, D. S., De Lillo, A., Koller, D., Cabrera-Mendoza, B., Clifford, R. E., Maihofer, A. X., Nievergelt, C. M., Curhan, G. C., Curhan, S. G., & Polimanti, R. (2023). Sex differences in the polygenic architecture of hearing problems in adults. Genome Medicine, 15(1), 36. https://doi.org/10.1186/s13073-023-01186-3
- Denisovan and Neanderthal archaic introgression differentially impacted the genetics of complex traits in modern populationsKoller D, Wendt F, Pathak G, De Lillo A, De Angelis F, Cabrera-Mendoza B, Tucci S, Polimanti R. Denisovan and Neanderthal archaic introgression differentially impacted the genetics of complex traits in modern populations BMC Biology 2022, 20: 249. PMID: 36344982, PMCID: PMC9641937, DOI: 10.1186/s12915-022-01449-2.
- A GENOME-WIDE CROSS-DISORDER ANALYSIS OF BIPOLAR DISORDER, SCHIZOPHRENIA, AND DEPRESSION REVEALS NOVEL PLEIOTROPIC LOCI AND PATHWAYSFriligkou E, Wendt F, Pathak G, Tylee D, De Angelis F, De Lillo A, Koller D, Cabrera-Mendoza B, Polimanti R. A GENOME-WIDE CROSS-DISORDER ANALYSIS OF BIPOLAR DISORDER, SCHIZOPHRENIA, AND DEPRESSION REVEALS NOVEL PLEIOTROPIC LOCI AND PATHWAYS European Neuropsychopharmacology 2022, 63: e254-e255. DOI: 10.1016/j.euroneuro.2022.07.454.
- Epigenome-Wide Analysis Reveals DNA Methylation Alteration in ZFP57 and Its Target RASGFR2 in a Mexican Population Cohort with AutismAspra Q, Cabrera-Mendoza B, Morales-Marín ME, Márquez C, Chicalote C, Ballesteros A, Aguilar M, Castro X, Gómez-Cotero A, Balboa-Verduzco AM, Albores-Gallo L, Nafate-López O, Marcín-Salazar CA, Sánchez P, Lanzagorta-Piñol N, López-Armenta FO, Nicolini H. Epigenome-Wide Analysis Reveals DNA Methylation Alteration in ZFP57 and Its Target RASGFR2 in a Mexican Population Cohort with Autism Children 2022, 9: 462. PMID: 35455506, PMCID: PMC9025761, DOI: 10.3390/children9040462.
- Genetically regulated multi-omics study for symptom clusters of posttraumatic stress disorder highlights pleiotropy with hematologic and cardio-metabolic traitsPathak GA, Singh K, Wendt FR, Fleming TW, Overstreet C, Koller D, Tylee DS, De Angelis F, Cabrera Mendoza B, Levey DF, Koenen KC, Krystal JH, Pietrzak RH, O’ Donell C, Gaziano JM, Falcone G, Stein MB, Gelernter J, Pasaniuc B, Mancuso N, Davis LK, Polimanti R. Genetically regulated multi-omics study for symptom clusters of posttraumatic stress disorder highlights pleiotropy with hematologic and cardio-metabolic traits Molecular Psychiatry 2022, 27: 1394-1404. PMID: 35241783, PMCID: PMC9210390, DOI: 10.1038/s41380-022-01488-9.
- Using phenotype risk scores to enhance gene discovery for generalized anxiety disorder and posttraumatic stress disorderWendt FR, Pathak GA, Deak JD, De Angelis F, Koller D, Cabrera-Mendoza B, Lebovitch DS, Levey DF, Stein MB, Kranzler HR, Koenen KC, Gelernter J, Huckins LM, Polimanti R. Using phenotype risk scores to enhance gene discovery for generalized anxiety disorder and posttraumatic stress disorder Molecular Psychiatry 2022, 27: 2206-2215. PMID: 35181757, PMCID: PMC9133008, DOI: 10.1038/s41380-022-01469-y.
- The integration of genetically-regulated transcriptomics and electronic health records highlights a pattern of medical outcomes related to increased hepatic transthyretin expressionPathak GA, De Lillo A, Wendt FR, De Angelis F, Koller D, Mendoza B, Jacoby D, Miller EJ, Buxbaum JN, Polimanti R. The integration of genetically-regulated transcriptomics and electronic health records highlights a pattern of medical outcomes related to increased hepatic transthyretin expression Amyloid 2021, 29: 110-119. PMID: 34935565, PMCID: PMC9213571, DOI: 10.1080/13506129.2021.2018678.
- Evaluación longitudinal mediante resonancia magnética del modelo de esquizofrenia de lesión neonatal en el hipocampo ventralGenis-Mendoza AD, Elizalde-Martínez C, Martínez-Magaña JJ, Cabrera-Mendoza B, Morales-Guadarrama A, Sacristán E, Beltrán-Villalobos I, Tovilla-Zarate CA, Nicolini H. Evaluación longitudinal mediante resonancia magnética del modelo de esquizofrenia de lesión neonatal en el hipocampo ventral Cirugía Y Cirujanos 2021, 89: 785-791. PMID: 34851586, DOI: 10.24875/ciru.20001027.
- COMORBID-PHENOME PREDICTION AND PHENOTYPE RISK SCORES INCREASE DATA AVAILABILITY FOR ANXIETY AND PTSD GENE DISCOVERYWendt F, Pathak G, Deak J, De Angelis F, Koller D, Cabrera-Mendoza B, Levey D, Stein M, Kranzler H, Koenen K, Gelernter J, Huckins L, Polimanti R. COMORBID-PHENOME PREDICTION AND PHENOTYPE RISK SCORES INCREASE DATA AVAILABILITY FOR ANXIETY AND PTSD GENE DISCOVERY European Neuropsychopharmacology 2021, 51: e6-e7. DOI: 10.1016/j.euroneuro.2021.07.023.
- Brain Gene Expression-DNA Methylation Correlation in Suicide Completers: Preliminary ResultsCabrera-Mendoza B, Martínez-Magaña JJ, Genis-Mendoza AD, Monroy-Jaramillo N, Walss-Bass C, Fries GR, García-Dolores F, López-Armenta M, Flores G, Vázquez-Roque RA, Nicolini H. Brain Gene Expression-DNA Methylation Correlation in Suicide Completers: Preliminary Results Revista De Investigación Clínica 2021, 72: 283-292. PMID: 33057323, DOI: 10.24875/ric.19003250.
- Brain Gene Expression-DNA Methylation Correlation in Suicide Completers: Preliminary ResultsCabrera-Mendoza B, Martínez-Magaña J, Genis-Mendoza A, Monroy-Jaramillo N, Walss-Bass C, Fries G, García-Dolores F, López-Armenta M, Flores G, Vázquez-Roque R, Nicolini H. Brain Gene Expression-DNA Methylation Correlation in Suicide Completers: Preliminary Results Revista De Investigación Clínica 2021, 72 DOI: 10.24875/ric.19003250.
- A meta-study on transcription factor networks in the suicidal brainCabrera-Mendoza B, de Anda-Jáuregui G, Nicolini H, Fresno C. A meta-study on transcription factor networks in the suicidal brain Journal Of Psychiatric Research 2021, 136: 23-31. PMID: 33548827, DOI: 10.1016/j.jpsychires.2021.01.037.
- Association of antibody titers and 5-HTTLPR gene polymorphisms in pediatric autoimmune neuropsychiatric disorder associated with streptococciGenis-Mendoza A, Nicolini H, Manrique V, López-Canovas L, Cabrera-Mendoza B, Bobes M, Lanzagorta N, Santana D. Association of antibody titers and 5-HTTLPR gene polymorphisms in pediatric autoimmune neuropsychiatric disorder associated with streptococci Salud Mental 2020, 43: 181-187. DOI: 10.17711/sm.0185-3325.2020.025.
- Brain Gene Expression-DNA Methylation Correlation in Suicide Completers: Preliminary Results.Cabrera-Mendoza B, Martínez-Magaña JJ, Genis-Mendoza AD, Monroy-Jaramillo N, Walss-Bass C, Fries GR, García-Dolores F, López-Armenta M, Flores G, Vázquez-Roque RA, Nicolini H. Brain Gene Expression-DNA Methylation Correlation in Suicide Completers: Preliminary Results. Revista De Investigación Clínica 2020, 73 PMID: 32488228.
- Diagnosis in PANDAS: An UpdateCabrera-Mendoza B, Genis-Mendoza A, Nicolini H. Diagnosis in PANDAS: An Update Current Psychiatry Research And Reviews 2020, 15: 237-247. DOI: 10.2174/2666082215666190917161514.
- Brain Gene Expression Profiling of Individuals With Dual Diagnosis Who Died by SuicideCabrera-Mendoza B, Fresno C, Monroy-Jaramillo N, Fries GR, Walss-Bass C, Glahn DC, Ostrosky-Wegman P, Genis-Mendoza AD, Martínez-Magaña JJ, Romero-Pimentel AL, Díaz-Otañez CE, García-Dolores F, González-Sáenz EE, Mendoza-Morales RC, Flores G, Vázquez-Roque R, Nicolini H. Brain Gene Expression Profiling of Individuals With Dual Diagnosis Who Died by Suicide Journal Of Dual Diagnosis 2019, 16: 177-190. PMID: 31774731, DOI: 10.1080/15504263.2019.1692160.
- Neuroanatomical features and its usefulness in classification of patients with PANDAS.Cabrera B, Romero-Rebollar C, Jiménez-Ángeles L, Genis-Mendoza AD, Flores J, Lanzagorta N, Arroyo M, de la Fuente-Sandoval C, Santana D, Medina-Bañuelos V, Sacristán E, Nicolini H. Neuroanatomical features and its usefulness in classification of patients with PANDAS. CNS Spectrums 2019, 24: 533-543. PMID: 30428956, DOI: 10.1017/S1092852918001268.
- Exploratory analysis of genetic variants influencing molecular traits in cerebral cortex of suicide completersRodríguez‐López M, Martínez‐Magaña J, Cabrera‐Mendoza B, Genis‐Mendoza A, García‐Dolores F, López‐Armenta M, Flores G, Vázquez‐Roque R, Nicolini H. Exploratory analysis of genetic variants influencing molecular traits in cerebral cortex of suicide completers American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2019, 183: 26-37. PMID: 31418530, DOI: 10.1002/ajmg.b.32752.
- Brain Gene Expression Pattern of Subjects with Completed Suicide and Comorbid Substance Use DisorderCabrera B, Monroy-Jaramillo N, Fries GR, Mendoza-Morales RC, García-Dolores F, Mendoza-Larios A, Diaz-Otañez C, Walss-Bass C, Glahn DC, Ostrosky-Wegman P, Fresno C, Nicolini H. Brain Gene Expression Pattern of Subjects with Completed Suicide and Comorbid Substance Use Disorder Complex Psychiatry 2018, 5: 60-73. PMID: 31019919, PMCID: PMC6465692, DOI: 10.1159/000493940.