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John Krystal, MD

Robert L. McNeil, Jr. Professor of Translational Research and Professor of Psychiatry, of Neuroscience, and of Psychology; Co-Director, Yale Center for Clinical Investigation; Chair, Psychiatry; Physician-in-Chief of Psychiatry, Yale New Haven Hospital; Director: NIAAA Center for the Translational Neuroscience of Alcoholism; Director, Clinical Neuroscience Division, VA National Center for PTSD

Contact Information

John Krystal, MD

Research Summary

Neurobiology; pharmacotherapy; genetics; neuroimaging; computational neuroscience

schizophrenia; alcoholism; PTSD; depression


Research Interests

Alcoholism; Drug Therapy; Genetics; Neurobiology; Psychiatry; Schizophrenia; Stress Disorders, Post-Traumatic; Veterans; Neuroimaging

Selected Publications

Clinical Trials

ConditionsStudy Title
Addictive Behaviors; Alcohol Addiction; Mental Health & Behavioral ResearchAlcohol Interaction Study
Mental Health & Behavioral ResearchEfficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study.
Diseases of the Nervous System; Mental Health & Behavioral ResearchTeen Brain and Behavior Study
Diseases of the Nervous System; Mental Health & Behavioral ResearchExamination of Glutamate and mGluR5 in Psychiatric Disorders
Mental Health & Behavioral ResearchAMPA Receptor Components of the Anti-Depressant Ketamine Response
Diseases of the Nervous System; Genetics - Adult; Genetics - Pediatric; Mental Health & Behavioral ResearchBrain Emotion Circuitry-Targeted Self-Monitoring and Regulation Therapy (BE-SMART)
Mental Health & Behavioral ResearchImaging mGluR5 and synaptic density in psychiatric disorders
Diseases of the Nervous System; Mental Health & Behavioral ResearchBiomarkers of Clinical Subtype and Treatment Response in Obsessive-Compulsive Disorder
Mental Health & Behavioral ResearchStudying the Adult Brain
COVID-19 Inpatient; COVID-19 Outpatient; Mental Health & Behavioral ResearchHave you had COVID-19?