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Gita Pathak, PhD

Postdoctoral Associate

Research & Publications
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Selected Publications

Genetic Liability to Posttraumatic Stress Disorder Symptoms and Its Association With Cardiometabolic and Respiratory OutcomesPathak G, Singh K, Choi K, Fang Y, Kouakou M, Lee Y, Zhou X, Fritsche L, Wendt F, Davis L, Polimanti R. Genetic Liability to Posttraumatic Stress Disorder Symptoms and Its Association With Cardiometabolic and Respiratory Outcomes. JAMA Psychiatry 2024, 81: 34-44. PMID: 37910111, PMCID: PMC10620678, DOI: 10.1001/jamapsychiatry.2023.4127.
Genetically regulated multi-omics study for symptom clusters of posttraumatic stress disorder highlights pleiotropy with hematologic and cardio-metabolic traitsPathak GA, Singh K, Wendt FR, Fleming TW, Overstreet C, Koller D, Tylee DS, De Angelis F, Cabrera Mendoza B, Levey DF, Koenen KC, Krystal JH, Pietrzak RH, O’ Donell C, Gaziano JM, Falcone G, Stein MB, Gelernter J, Pasaniuc B, Mancuso N, Davis LK, Polimanti R. Genetically regulated multi-omics study for symptom clusters of posttraumatic stress disorder highlights pleiotropy with hematologic and cardio-metabolic traits. Molecular Psychiatry 2022, 27: 1394-1404. PMID: 35241783, PMCID: PMC9210390, DOI: 10.1038/s41380-022-01488-9.
Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalizationPathak GA, Singh K, Miller-Fleming TW, Wendt FR, Ehsan N, Hou K, Johnson R, Lu Z, Gopalan S, Yengo L, Mohammadi P, Pasaniuc B, Polimanti R, Davis LK, Mancuso N. Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization. Nature Communications 2021, 12: 4569. PMID: 34315903, PMCID: PMC8316582, DOI: 10.1038/s41467-021-24824-z.
A first update on mapping the human genetic architecture of COVID-19.COVID-19 Host Genetics Initiative. A first update on mapping the human genetic architecture of COVID-19. Nature 2022, 608: E1-E10. PMID: 35922517, DOI: 10.1038/s41586-022-04826-7.
Mapping the human genetic architecture of COVID-19.COVID-19 Host Genetics Initiative. Mapping the human genetic architecture of COVID-19. Nature 2021, 600: 472-477. PMID: 34237774, DOI: 10.1038/s41586-021-03767-x.
ACE2 Netlas: In silico Functional Characterization and Drug-Gene Interactions of ACE2 Gene Network to Understand Its Potential Involvement in COVID-19 SusceptibilityPathak GA, Wendt FR, Goswami A, Koller D, De Angelis F, Initiative C, Polimanti R. ACE2 Netlas: In silico Functional Characterization and Drug-Gene Interactions of ACE2 Gene Network to Understand Its Potential Involvement in COVID-19 Susceptibility. Frontiers In Genetics 2021, 12: 698033. PMID: 34512723, PMCID: PMC8429844, DOI: 10.3389/fgene.2021.698033.
Genetically-regulated transcriptomics & copy number variation of proctitis points to altered mitochondrial and DNA repair mechanisms in individuals of European ancestryPathak GA, Polimanti R, Silzer TK, Wendt FR, Chakraborty R, Phillips NR. Genetically-regulated transcriptomics & copy number variation of proctitis points to altered mitochondrial and DNA repair mechanisms in individuals of European ancestry. BMC Cancer 2020, 20: 954. PMID: 33008348, PMCID: PMC7530964, DOI: 10.1186/s12885-020-07457-1.
Two‐stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancerPathak GA, Zhou Z, Silzer TK, Barber RC, Phillips NR, for the Alzheimer's Disease Neuroimaging Initiative B. Two‐stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancer. Alzheimer's & Dementia 2020, 16: 162-177. PMID: 31914222, DOI: 10.1002/alz.12003.
Genome-Wide Methylation of Mild Cognitive Impairment in Mexican Americans Highlights Genes Involved in Synaptic Transport, Alzheimer's Disease-Precursor Phenotypes, and Metabolic Morbidities.Pathak GA, Silzer TK, Sun J, Zhou Z, Daniel AA, Johnson L, O'Bryant S, Phillips NR, Barber RC. Genome-Wide Methylation of Mild Cognitive Impairment in Mexican Americans Highlights Genes Involved in Synaptic Transport, Alzheimer's Disease-Precursor Phenotypes, and Metabolic Morbidities. Journal Of Alzheimer's Disease 2019, 72: 733-749. PMID: 31640099, DOI: 10.3233/jad-190634.
Brainwide Mendelian Randomization Study of Anxiety Disorders and SymptomsZanoaga M, Friligkou E, He J, Pathak G, Koller D, Cabrera-Mendoza B, Stein M, Polimanti R. Brainwide Mendelian Randomization Study of Anxiety Disorders and Symptoms. Biological Psychiatry 2023, 95: 810-817. PMID: 37967698, PMCID: PMC10978301, DOI: 10.1016/j.biopsych.2023.11.006.
Characterizing the polygenic architecture of complex traits in populations of East Asian and European descentDe Lillo A, Wendt F, Pathak G, Polimanti R. Characterizing the polygenic architecture of complex traits in populations of East Asian and European descent. Human Genomics 2023, 17: 67. PMID: 37475089, PMCID: PMC10360343, DOI: 10.1186/s40246-023-00514-3.
Modeling the longitudinal changes of ancestry diversity in the Million Veteran ProgramWendt F, Pathak G, Vahey J, Qin X, Koller D, Cabrera-Mendoza B, Haeny A, Harrington K, Rajeevan N, Duong L, Levey D, De Angelis F, De Lillo A, Bigdeli T, Pyarajan S, Gaziano J, Gelernter J, Aslan M, Provenzale D, Helmer D, Hauser E, Polimanti R. Modeling the longitudinal changes of ancestry diversity in the Million Veteran Program. Human Genomics 2023, 17: 46. PMID: 37268996, PMCID: PMC10239111, DOI: 10.1186/s40246-023-00487-3.
Declining autozygosity over time: An exploration in over 1 million individuals from three diverse cohortsColbert S, Wendt F, Pathak G, Helmer D, Hauser E, Keller M, Polimanti R, Johnson E. Declining autozygosity over time: An exploration in over 1 million individuals from three diverse cohorts. American Journal Of Human Genetics 2023, 110: 1008-1014. PMID: 37178685, PMCID: PMC10257001, DOI: 10.1016/j.ajhg.2023.04.007.
Sex differences in the polygenic architecture of hearing problems in adultsDe Angelis F, Zeleznik O, Wendt F, Pathak G, Tylee D, De Lillo A, Koller D, Cabrera-Mendoza B, Clifford R, Maihofer A, Nievergelt C, Curhan G, Curhan S, Polimanti R. Sex differences in the polygenic architecture of hearing problems in adults. Genome Medicine 2023, 15: 36. PMID: 37165447, PMCID: PMC10173489, DOI: 10.1186/s13073-023-01186-3.
Epidemiologic and Genetic Associations of Endometriosis With Depression, Anxiety, and Eating DisordersKoller D, Pathak G, Wendt F, Tylee D, Levey D, Overstreet C, Gelernter J, Taylor H, Polimanti R. Epidemiologic and Genetic Associations of Endometriosis With Depression, Anxiety, and Eating Disorders. Obstetrical & Gynecological Survey 2023, 78: 282-283. DOI: 10.1097/01.ogx.0000935848.53207.07.
Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disordersHatoum A, Colbert S, Johnson E, Huggett S, Deak J, Pathak G, Jennings M, Paul S, Karcher N, Hansen I, Baranger D, Edwards A, Grotzinger A, Tucker-Drob E, Kranzler H, Davis L, Sanchez-Roige S, Polimanti R, Gelernter J, Edenberg H, Bogdan R, Agrawal A. Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders. Nature Mental Health 2023, 1: 210-223. PMID: 37250466, PMCID: PMC10217792, DOI: 10.1038/s44220-023-00034-y.
Phenome-wide genetic-correlation analysis and genetically informed causal inference of amyotrophic lateral sclerosisD’Antona S, Pathak G, Koller D, Porro D, Cava C, Polimanti R. Phenome-wide genetic-correlation analysis and genetically informed causal inference of amyotrophic lateral sclerosis. Human Genetics 2023, 142: 1173-1183. PMID: 36773064, PMCID: PMC10449723, DOI: 10.1007/s00439-023-02525-5.
Epidemiologic and Genetic Associations of Endometriosis With Depression, Anxiety, and Eating DisordersKoller D, Pathak G, Wendt F, Tylee D, Levey D, Overstreet C, Gelernter J, Taylor H, Polimanti R. Epidemiologic and Genetic Associations of Endometriosis With Depression, Anxiety, and Eating Disorders. JAMA Network Open 2023, 6: e2251214. PMID: 36652249, PMCID: PMC9856929, DOI: 10.1001/jamanetworkopen.2022.51214.
Phenome-wide association study of loci harboring de novo tandem repeat mutations in UK Biobank exomesWendt F, Pathak G, Polimanti R. Phenome-wide association study of loci harboring de novo tandem repeat mutations in UK Biobank exomes. Nature Communications 2022, 13: 7682. PMID: 36509785, PMCID: PMC9744822, DOI: 10.1038/s41467-022-35423-x.
Denisovan and Neanderthal archaic introgression differentially impacted the genetics of complex traits in modern populationsKoller D, Wendt F, Pathak G, De Lillo A, De Angelis F, Cabrera-Mendoza B, Tucci S, Polimanti R. Denisovan and Neanderthal archaic introgression differentially impacted the genetics of complex traits in modern populations. BMC Biology 2022, 20: 249. PMID: 36344982, PMCID: PMC9641937, DOI: 10.1186/s12915-022-01449-2.
Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cellsLynall ME, Soskic B, Hayhurst J, Schwartzentruber J, Levey DF, Pathak GA, Polimanti R, Gelernter J, Stein MB, Trynka G, Clatworthy MR, Bullmore E. Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells. Nature Communications 2022, 13: 6102. PMID: 36243721, PMCID: PMC9569335, DOI: 10.1038/s41467-022-33885-7.
Understanding the comorbidity between posttraumatic stress severity and coronary artery disease using genome-wide information and electronic health recordsPolimanti R, Wendt FR, Pathak GA, Tylee DS, Tcheandjieu C, Hilliard AT, Levey DF, Adhikari K, Gaziano JM, O’Donnell C, Assimes TL, Stein MB, Gelernter J. Understanding the comorbidity between posttraumatic stress severity and coronary artery disease using genome-wide information and electronic health records. Molecular Psychiatry 2022, 27: 3961-3969. PMID: 35986173, DOI: 10.1038/s41380-022-01735-z.
Sex-Specific Genetic and Transcriptomic Liability to NeuroticismWendt FR, Pathak GA, Singh K, Stein MB, Koenen KC, Krystal JH, Gelernter J, Davis LK, Polimanti R. Sex-Specific Genetic and Transcriptomic Liability to Neuroticism. Biological Psychiatry 2022, 93: 243-252. PMID: 36244801, PMCID: PMC10508260, DOI: 10.1016/j.biopsych.2022.07.019.
An Atlas of Genetic Correlations and Genetically Informed Associations Linking Psychiatric and Immune-Related PhenotypesTylee DS, Lee YK, Wendt FR, Pathak GA, Levey DF, De Angelis F, Gelernter J, Polimanti R. An Atlas of Genetic Correlations and Genetically Informed Associations Linking Psychiatric and Immune-Related Phenotypes. JAMA Psychiatry 2022, 79: 667-676. PMID: 35507366, PMCID: PMC9069342, DOI: 10.1001/jamapsychiatry.2022.0914.
Characterizing the Genetic Effects Linking Psychiatric and Immune-Related PhenotypesTylee D, Lee Y, Wendt F, Pathak G, Levey D, De Angelis F, Gelernter J, Polimanti R. Characterizing the Genetic Effects Linking Psychiatric and Immune-Related Phenotypes. Biological Psychiatry 2022, 91: s72-s73. DOI: 10.1016/j.biopsych.2022.02.200.
Expression of stable and reliable preference and aversion phenotypes following place conditioning with psychostimulantsShetty R, Rutledge M, LeBouf A, Mock J, Pathak G, Forster M. Expression of stable and reliable preference and aversion phenotypes following place conditioning with psychostimulants. Psychopharmacology 2022, 239: 2593-2603. PMID: 35482071, DOI: 10.1007/s00213-022-06130-8.
Using phenotype risk scores to enhance gene discovery for generalized anxiety disorder and posttraumatic stress disorderWendt FR, Pathak GA, Deak JD, De Angelis F, Koller D, Cabrera-Mendoza B, Lebovitch DS, Levey DF, Stein MB, Kranzler HR, Koenen KC, Gelernter J, Huckins LM, Polimanti R. Using phenotype risk scores to enhance gene discovery for generalized anxiety disorder and posttraumatic stress disorder. Molecular Psychiatry 2022, 27: 2206-2215. PMID: 35181757, PMCID: PMC9133008, DOI: 10.1038/s41380-022-01469-y.
Host Genetic Liability for Severe COVID-19 Associates with Alcohol Drinking Behavior and Diabetic Outcomes in Participants of European DescentWendt FR, De Lillo A, Pathak GA, De Angelis F, Initiative C, Polimanti R. Host Genetic Liability for Severe COVID-19 Associates with Alcohol Drinking Behavior and Diabetic Outcomes in Participants of European Descent. Frontiers In Genetics 2021, 12: 765247. PMID: 34966408, PMCID: PMC8711039, DOI: 10.3389/fgene.2021.765247.
Drinking and smoking polygenic risk is associated with childhood and early-adulthood psychiatric and behavioral traits independently of substance use and psychiatric genetic riskDe Angelis F, Wendt FR, Pathak GA, Tylee DS, Goswami A, Gelernter J, Polimanti R. Drinking and smoking polygenic risk is associated with childhood and early-adulthood psychiatric and behavioral traits independently of substance use and psychiatric genetic risk. Translational Psychiatry 2021, 11: 586. PMID: 34775470, PMCID: PMC8590689, DOI: 10.1038/s41398-021-01713-z.
Posttraumatic Stress Disorder and Cardiovascular DiseaseO’Donnell C, Longacre L, Cohen BE, Fayad ZA, Gillespie CF, Liberzon I, Pathak GA, Polimanti R, Risbrough V, Ursano RJ, Heide R, Yancy CW, Vaccarino V, Sopko G, Stein MB. Posttraumatic Stress Disorder and Cardiovascular Disease. JAMA Cardiology 2021, 6: 1207-1216. PMID: 34259831, DOI: 10.1001/jamacardio.2021.2530.
Disentangling sex differences in the shared genetic architecture of posttraumatic stress disorder, traumatic experiences, and social support with body size and compositionCarvalho C, Wendt FR, Pathak GA, Maihofer AX, Stein DJ, Sumner JA, Hemmings SMJ, Nievergelt CM, Koenen KC, Gelernter J, Belangero SI, Polimanti R. Disentangling sex differences in the shared genetic architecture of posttraumatic stress disorder, traumatic experiences, and social support with body size and composition. Neurobiology Of Stress 2021, 15: 100400. PMID: 34611531, PMCID: PMC8477211, DOI: 10.1016/j.ynstr.2021.100400.
Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directionsLevey DF, Stein MB, Wendt FR, Pathak GA, Zhou H, Aslan M, Quaden R, Harrington KM, Nuñez YZ, Overstreet C, Radhakrishnan K, Sanacora G, McIntosh AM, Shi J, Shringarpure SS, Concato J, Polimanti R, Gelernter J. Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions. Nature Neuroscience 2021, 24: 954-963. PMID: 34045744, PMCID: PMC8404304, DOI: 10.1038/s41593-021-00860-2.
Role of microbes in the pathogenesis of neuropsychiatric disordersGoswami A, Wendt FR, Pathak GA, Tylee DS, De Angelis F, De Lillo A, Polimanti R. Role of microbes in the pathogenesis of neuropsychiatric disorders. Frontiers In Neuroendocrinology 2021, 62: 100917. PMID: 33957173, PMCID: PMC8364482, DOI: 10.1016/j.yfrne.2021.100917.
Biobank Scale Pharmacogenomics Informs the Genetic Underpinnings of Simvastatin UseWendt FR, Koller D, Pathak GA, Jacoby D, Miller EJ, Polimanti R. Biobank Scale Pharmacogenomics Informs the Genetic Underpinnings of Simvastatin Use. Clinical Pharmacology & Therapeutics 2021, 110: 777-785. PMID: 33837531, PMCID: PMC8376807, DOI: 10.1002/cpt.2260.
Cross-ancestry genome-wide association studies identified heterogeneous loci associated with differences of allele frequency and regulome tagging between participants of European descent and other ancestry groups from the UK Biobank.De Lillo A, D'Antona S, Pathak GA, Wendt FR, De Angelis F, Fuciarelli M, Polimanti R. Cross-ancestry genome-wide association studies identified heterogeneous loci associated with differences of allele frequency and regulome tagging between participants of European descent and other ancestry groups from the UK Biobank. Human Molecular Genetics 2021, 30: 1457-1467. PMID: 33890984, PMCID: PMC8283210, DOI: 10.1093/hmg/ddab114.
Pleiotropic effects of telomere length loci with brain morphology and brain tissue expression.Pathak GA, Wendt FR, Levey DF, Mecca AP, van Dyck CH, Gelernter J, Polimanti R. Pleiotropic effects of telomere length loci with brain morphology and brain tissue expression. Human Molecular Genetics 2021, 30: 1360-1370. PMID: 33831179, PMCID: PMC8255129, DOI: 10.1093/hmg/ddab102.
Sex-stratified gene-by-environment genome-wide interaction study of trauma, posttraumatic-stress, and suicidalityWendt FR, Pathak GA, Levey DF, Nuñez YZ, Overstreet C, Tyrrell C, Adhikari K, De Angelis F, Tylee DS, Goswami A, Krystal JH, Abdallah CG, Stein MB, Kranzler HR, Gelernter J, Polimanti R. Sex-stratified gene-by-environment genome-wide interaction study of trauma, posttraumatic-stress, and suicidality. Neurobiology Of Stress 2021, 14: 100309. PMID: 33665242, PMCID: PMC7905234, DOI: 10.1016/j.ynstr.2021.100309.
Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran ProgramStein MB, Levey DF, Cheng Z, Wendt FR, Harrington K, Pathak GA, Cho K, Quaden R, Radhakrishnan K, Girgenti MJ, Ho YA, Posner D, Aslan M, Duman RS, Zhao H, Polimanti R, Concato J, Gelernter J. Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Program. Nature Genetics 2021, 53: 174-184. PMID: 33510476, PMCID: PMC7972521, DOI: 10.1038/s41588-020-00767-x.
Multi-environment gene interactions linked to the interplay between polysubstance dependence and suicidalityPolimanti R, Levey DF, Pathak GA, Wendt FR, Nunez YZ, Ursano RJ, Kessler RC, Kranzler HR, Stein MB, Gelernter J. Multi-environment gene interactions linked to the interplay between polysubstance dependence and suicidality. Translational Psychiatry 2021, 11: 34. PMID: 33431810, PMCID: PMC7801457, DOI: 10.1038/s41398-020-01153-1.
Epigenomic Profiles of African-American Transthyretin Val122Ile Carriers Reveals Putatively Dysregulated Amyloid MechanismsPathak GA, Wendt FR, De Lillo A, Nunez YZ, Goswami A, De Angelis F, Fuciarelli M, Kranzler HR, Gelernter J, Polimanti R. Epigenomic Profiles of African-American Transthyretin Val122Ile Carriers Reveals Putatively Dysregulated Amyloid Mechanisms. Circulation Genomic And Precision Medicine 2021, 14: e003011. PMID: 33428857, PMCID: PMC7887108, DOI: 10.1161/circgen.120.003011.
Multiomics Investigation of Hypertension and White Matter Hyperintensity as a Source of Vascular Dementia or a Comorbidity to Alzheimer’s DiseasePathak G, Barber R, Phillips N. Multiomics Investigation of Hypertension and White Matter Hyperintensity as a Source of Vascular Dementia or a Comorbidity to Alzheimer’s Disease. Current Alzheimer Research 2021, 18: 171-177. PMID: 33888050, DOI: 10.2174/1567205018666210422133547.
Multivariate genome-wide analysis of education, socioeconomic status and brain phenomeWendt FR, Pathak GA, Lencz T, Krystal JH, Gelernter J, Polimanti R. Multivariate genome-wide analysis of education, socioeconomic status and brain phenome. Nature Human Behaviour 2020, 5: 482-496. PMID: 33349686, PMCID: PMC8068566, DOI: 10.1038/s41562-020-00980-y.
Characterizing the effect of background selection on the polygenicity of brain-related traitsWendt FR, Pathak GA, Overstreet C, Tylee DS, Gelernter J, Atkinson EG, Polimanti R. Characterizing the effect of background selection on the polygenicity of brain-related traits. Genomics 2020, 113: 111-119. PMID: 33278486, PMCID: PMC7855394, DOI: 10.1016/j.ygeno.2020.11.032.
Epigenetic profiling of Italian patients identified methylation sites associated with hereditary transthyretin amyloidosisDe Lillo A, Pathak GA, De Angelis F, Di Girolamo M, Luigetti M, Sabatelli M, Perfetto F, Frusconi S, Manfellotto D, Fuciarelli M, Polimanti R. Epigenetic profiling of Italian patients identified methylation sites associated with hereditary transthyretin amyloidosis. Clinical Epigenetics 2020, 12: 176. PMID: 33203445, PMCID: PMC7672937, DOI: 10.1186/s13148-020-00967-6.
Attachment Style Moderates Polygenic Risk for Posttraumatic Stress in United States Military Veterans: Results From the National Health and Resilience in Veterans StudyTamman AJF, Wendt FR, Pathak GA, Krystal JH, Montalvo-Ortiz JL, Southwick SM, Sippel LM, Gelernter J, Polimanti R, Pietrzak RH. Attachment Style Moderates Polygenic Risk for Posttraumatic Stress in United States Military Veterans: Results From the National Health and Resilience in Veterans Study. Biological Psychiatry 2020, 89: 878-887. PMID: 33276944, DOI: 10.1016/j.biopsych.2020.09.018.
Polygenic risk for autism spectrum disorder associates with anger recognition in a neurodevelopment-focused phenome-wide scan of unaffected youths from a population-based cohortWendt FR, Carvalho CM, Pathak GA, Gelernter J, Polimanti R. Polygenic risk for autism spectrum disorder associates with anger recognition in a neurodevelopment-focused phenome-wide scan of unaffected youths from a population-based cohort. PLOS Genetics 2020, 16: e1009036. PMID: 32941431, PMCID: PMC7523983, DOI: 10.1371/journal.pgen.1009036.
Patient genetics is linked to chronic wound microbiome composition and healingTipton C, Wolcott R, Sanford N, Miller C, Pathak G, Silzer T, Sun J, Fleming D, Rumbaugh K, Little T, Phillips N, Phillips C. Patient genetics is linked to chronic wound microbiome composition and healing. PLOS Pathogens 2020, 16: e1008511. PMID: 32555671, PMCID: PMC7302439, DOI: 10.1371/journal.ppat.1008511.
Mitochondrial tRNA methylation in Alzheimer’s disease and progressive supranuclear palsySilzer T, Pathak G, Phillips N. Mitochondrial tRNA methylation in Alzheimer’s disease and progressive supranuclear palsy. BMC Medical Genomics 2020, 13: 71. PMID: 32429992, PMCID: PMC7236490, DOI: 10.1186/s12920-020-0727-9.
Complex Multi-Environment Gene Interactions at the Basis of the Interplay Between Polysubstance Abuse and Suicide BehaviorsPolimanti R, Levey D, Pathak G, Wendt F, Nunez Y, Kranzler H, Stein M, Gelernter J. Complex Multi-Environment Gene Interactions at the Basis of the Interplay Between Polysubstance Abuse and Suicide Behaviors. Biological Psychiatry 2020, 87: s155. DOI: 10.1016/j.biopsych.2020.02.411.
Education and Socioeconomic Status Mask the Identification of Brain Cell Types in GWAS of Mental Health and DiseaseWendt F, Pathak G, Lencz T, Krystal J, Gelernter J, Polimanti R. Education and Socioeconomic Status Mask the Identification of Brain Cell Types in GWAS of Mental Health and Disease. Biological Psychiatry 2020, 87: s110. DOI: 10.1016/j.biopsych.2020.02.302.
Heterogeneity and Polygenicity in Psychiatric Disorders: A Genome-Wide PerspectiveWendt FR, Pathak GA, Tylee DS, Goswami A, Polimanti R. Heterogeneity and Polygenicity in Psychiatric Disorders: A Genome-Wide Perspective. Chronic Stress 2020, 4: 2470547020924844. PMID: 32518889, PMCID: PMC7254587, DOI: 10.1177/2470547020924844.
Deciphering the Biological Mechanisms Underlying the Genome-Wide Associations between Computerized Device Use and Psychiatric DisordersWendt FR, Carvalho C, Pathak GA, Gelernter J, Polimanti R. Deciphering the Biological Mechanisms Underlying the Genome-Wide Associations between Computerized Device Use and Psychiatric Disorders. Journal Of Clinical Medicine 2019, 8: 2040. PMID: 31766499, PMCID: PMC6947231, DOI: 10.3390/jcm8122040.
Circulating mitochondrial DNA: New indices of type 2 diabetes-related cognitive impairment in Mexican AmericansSilzer T, Barber R, Sun J, Pathak G, Johnson L, O’Bryant S, Phillips N. Circulating mitochondrial DNA: New indices of type 2 diabetes-related cognitive impairment in Mexican Americans. PLOS ONE 2019, 14: e0213527. PMID: 30861027, PMCID: PMC6414026, DOI: 10.1371/journal.pone.0213527.
Global genetic variation of select opiate metabolism genes in self-reported healthy individualsWendt FR, Pathak G, Sajantila A, Chakraborty R, Budowle B. Global genetic variation of select opiate metabolism genes in self-reported healthy individuals. The Pharmacogenomics Journal 2017, 18: 281-294. PMID: 28398354, DOI: 10.1038/tpj.2017.13.

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Gita Pathak, PhD

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