Mihaela Aslan, PhD
Research Scientist (General Medicine)
Research & Publications
Biography
Locations
Coauthors
Selected Publications
- Metformin prescription for U.S. veterans with prediabetes, 2010–2019Gulanski B, Goulet J, Radhakrishnan K, Ko J, Li Y, Rajeevan N, Lee K, Heberer K, Lynch J, Streja E, Mutalik P, Cheung K, Concato J, Shih M, Lee J, Aslan M. Metformin prescription for U.S. veterans with prediabetes, 2010–2019. Journal Of Investigative Medicine 2023, 72: 139-150. PMID: 37668313, DOI: 10.1177/10815589231201141.
- 88. GENETIC ARCHITECTURE OF SCHIZOPHRENIA IN AFRICAN ANCESTRY INDIVIDUALSBigdeli T, Gorman B, Voloudakis G, Chatzinakos C, Barr P, Burstein D, Genovese G, Pyarajan S, Huang G, Pato C, Pato M, Fanous A, Aslan M, Harvey P, Roussos P. 88. GENETIC ARCHITECTURE OF SCHIZOPHRENIA IN AFRICAN ANCESTRY INDIVIDUALS. European Neuropsychopharmacology 2023, 75: s103. DOI: 10.1016/j.euroneuro.2023.08.191.
- Early predictors of chronic posttraumatic stress disorder symptom trajectories in U.S. Army soldiers deployed to the Iraq war zoneVasterling J, Franz M, Lee L, Kaiser A, Proctor S, Marx B, Schnurr P, Ko J, Concato J, Aslan M. Early predictors of chronic posttraumatic stress disorder symptom trajectories in U.S. Army soldiers deployed to the Iraq war zone. Journal Of Traumatic Stress 2023, 36: 955-967. PMID: 37608526, DOI: 10.1002/jts.22964.
- Anti–SARS-CoV-2 Pharmacotherapies Among Nonhospitalized US Veterans, January 2022 to January 2023Yan L, Streja E, Li Y, Rajeevan N, Rowneki M, Berry K, Hynes D, Cunningham F, Huang G, Aslan M, Ioannou G, Bajema K. Anti–SARS-CoV-2 Pharmacotherapies Among Nonhospitalized US Veterans, January 2022 to January 2023. JAMA Network Open 2023, 6: e2331249. PMID: 37651140, PMCID: PMC10472184, DOI: 10.1001/jamanetworkopen.2023.31249.
- Effectiveness of COVID-19 Treatment With Nirmatrelvir–Ritonavir or Molnupiravir Among U.S. Veterans: Target Trial Emulation Studies With One-Month and Six-Month OutcomesBajema K, Berry K, Streja E, Rajeevan N, Li Y, Mutalik P, Yan L, Cunningham F, Hynes D, Rowneki M, Bohnert A, Boyko E, Iwashyna T, Maciejewski M, Osborne T, Viglianti E, Aslan M, Huang G, Ioannou G. Effectiveness of COVID-19 Treatment With Nirmatrelvir–Ritonavir or Molnupiravir Among U.S. Veterans: Target Trial Emulation Studies With One-Month and Six-Month Outcomes. Annals Of Internal Medicine 2023, 176: m22-3565. PMID: 37276589, PMCID: PMC10243488, DOI: 10.7326/m22-3565.
- Modeling the longitudinal changes of ancestry diversity in the Million Veteran ProgramWendt F, Pathak G, Vahey J, Qin X, Koller D, Cabrera-Mendoza B, Haeny A, Harrington K, Rajeevan N, Duong L, Levey D, De Angelis F, De Lillo A, Bigdeli T, Pyarajan S, Gaziano J, Gelernter J, Aslan M, Provenzale D, Helmer D, Hauser E, Polimanti R. Modeling the longitudinal changes of ancestry diversity in the Million Veteran Program. Human Genomics 2023, 17: 46. PMID: 37268996, PMCID: PMC10239111, DOI: 10.1186/s40246-023-00487-3.
- 561. Lifetime Consequences and Correlates of Anticholinergic Medication Burden in the VA Healthcare SystemBigdeli T, Joshi Y, Li Y, Rajeevan N, Sayward F, Przygodszki R, Huang G, Pyarajan S, Muralidhar S, Gaziano J, Braff D, Light G, Aslan M, Roussos P, Harvey P. 561. Lifetime Consequences and Correlates of Anticholinergic Medication Burden in the VA Healthcare System. Biological Psychiatry 2023, 93: s321. DOI: 10.1016/j.biopsych.2023.02.801.
- Association of Gulf War Illness with Characteristics in Deployed vs. Non-Deployed Gulf War Era Veterans in the Cooperative Studies Program 2006/Million Veteran Program 029 Cohort: A Cross-Sectional AnalysisDuong L, Djotsa A, Vahey J, Steele L, Quaden R, Harrington K, Ahmed S, Polimanti R, Streja E, Gaziano J, Concato J, Zhao H, Radhakrishnan K, Hauser E, Helmer D, Aslan M, Gifford E. Association of Gulf War Illness with Characteristics in Deployed vs. Non-Deployed Gulf War Era Veterans in the Cooperative Studies Program 2006/Million Veteran Program 029 Cohort: A Cross-Sectional Analysis. International Journal Of Environmental Research And Public Health 2022, 20: 258. PMID: 36612580, PMCID: PMC9819371, DOI: 10.3390/ijerph20010258.
- Early Adoption of Anti–SARS-CoV-2 Pharmacotherapies Among US Veterans With Mild to Moderate COVID-19, January and February 2022Bajema K, Wang X, Hynes D, Rowneki M, Hickok A, Cunningham F, Bohnert A, Boyko E, Iwashyna T, Maciejewski M, Viglianti E, Streja E, Yan L, Aslan M, Huang G, Ioannou G. Early Adoption of Anti–SARS-CoV-2 Pharmacotherapies Among US Veterans With Mild to Moderate COVID-19, January and February 2022. JAMA Network Open 2022, 5: e2241434. PMID: 36367727, PMCID: PMC9652752, DOI: 10.1001/jamanetworkopen.2022.41434.
- NEW BIOLOGICAL INSIGHTS FROM MULTI-ANCESTRY GENOMIC ANALYSES OF SCHIZOPHRENIA AND BIPOLAR DISORDERBigdeli T, Gorman B, Voloudakis G, Genovese G, Iyegbe C, Barr P, Li Y, Pato M, Pato C, Fanous A, Muralidhar S, Aslan M, Pyarajan S, Harvey P, Roussos P. NEW BIOLOGICAL INSIGHTS FROM MULTI-ANCESTRY GENOMIC ANALYSES OF SCHIZOPHRENIA AND BIPOLAR DISORDER. European Neuropsychopharmacology 2022, 63: e24-e25. DOI: 10.1016/j.euroneuro.2022.07.056.
- CORRELATES AND CONSEQUENCES OF EXTERNALIZING RISK IN THE MILLION VETERANS PROGRAMBarr P, Bigdeli T, Kosten T, Swann A, Graham D, Lipsky R, Nielsen D, Aslan M, Dick D, Harden K, Harvey P, Kimbrel N, Beckham J. CORRELATES AND CONSEQUENCES OF EXTERNALIZING RISK IN THE MILLION VETERANS PROGRAM. European Neuropsychopharmacology 2022, 63: e257. DOI: 10.1016/j.euroneuro.2022.07.459.
- P515. Genomic Analyses of Schizophrenia and Bipolar Disorder Patients With Very Poor OutcomesHarvey P, Bigdeli T, Fanous A, Rajeevan N, Gorman B, Genovese G, Li Y, Sayward F, Pyarajan S, Aslan M. P515. Genomic Analyses of Schizophrenia and Bipolar Disorder Patients With Very Poor Outcomes. Biological Psychiatry 2022, 91: s297. DOI: 10.1016/j.biopsych.2022.02.752.
- P513. New Biological Insights From Multi-Ancestry Genomic Analyses of Schizophrenia and Bipolar Disorder: A Cooperative Studies Program #572 and Million Veteran Program (MVP) StudyBigdeli T, Voloudakis G, Gorman B, Genovese G, 572 C, Program M, Fanous A, Aslan M, Harvey P, Roussos P. P513. New Biological Insights From Multi-Ancestry Genomic Analyses of Schizophrenia and Bipolar Disorder: A Cooperative Studies Program #572 and Million Veteran Program (MVP) Study. Biological Psychiatry 2022, 91: s296. DOI: 10.1016/j.biopsych.2022.02.750.
- W71. PENETRANCE AND PLEIOTROPY OF POLYGENIC RISK SCORES FOR SCHIZOPHRENIA, BIPOLAR DISORDER, AND MAJOR DEPRESSION IN 660,000 US VETERANSBigdeli T, Voloudakis G, Barr P, Li Y, Gorman B, Gleason T, Przygodzki R, Huang G, Pyarajan S, Muralidhar S, Gaziano M, Aslan M, Fanous A, Harvey P, Roussos P. W71. PENETRANCE AND PLEIOTROPY OF POLYGENIC RISK SCORES FOR SCHIZOPHRENIA, BIPOLAR DISORDER, AND MAJOR DEPRESSION IN 660,000 US VETERANS. European Neuropsychopharmacology 2021, 51: e182. DOI: 10.1016/j.euroneuro.2021.08.156.
- Genomics of Gulf War Illness in U.S. Veterans Who Served during the 1990–1991 Persian Gulf War: Methods and Rationale for Veterans Affairs Cooperative Study #2006Radhakrishnan K, Hauser ER, Polimanti R, Helmer DA, Provenzale D, McNeil RB, Maffucci A, Quaden R, Zhao H, Whitbourne SB, Harrington KM, Vahey J, Gelernter J, Levey DF, Huang GD, Gaziano JM, Concato J, Aslan M. Genomics of Gulf War Illness in U.S. Veterans Who Served during the 1990–1991 Persian Gulf War: Methods and Rationale for Veterans Affairs Cooperative Study #2006. Brain Sciences 2021, 11: 845. PMID: 34202057, PMCID: PMC8301942, DOI: 10.3390/brainsci11070845.
- Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directionsLevey DF, Stein MB, Wendt FR, Pathak GA, Zhou H, Aslan M, Quaden R, Harrington KM, Nuñez YZ, Overstreet C, Radhakrishnan K, Sanacora G, McIntosh AM, Shi J, Shringarpure SS, Concato J, Polimanti R, Gelernter J. Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions. Nature Neuroscience 2021, 24: 954-963. PMID: 34045744, PMCID: PMC8404304, DOI: 10.1038/s41593-021-00860-2.
- Genomic and Phenomic Correlates of Suicidality Among US Veterans With Schizophrenia or Bipolar DisorderBigdeli T, Peterson R, Khankari N, Rajeevan N, Swann A, Sayward F, Meyers J, Li Y, Nielsen D, Wilkinson A, Graham D, O'Leary T, Zhao H, Cheung K, Mane S, Miller P, Brophy M, Program M, Przygodszki R, Siever L, Pyarajan S, Gleason T, Muralidhar S, Gaziano J, Concato J, Huang G, Fanous A, Aslan M, Kosten T, Harvey P. Genomic and Phenomic Correlates of Suicidality Among US Veterans With Schizophrenia or Bipolar Disorder. Biological Psychiatry 2021, 89: s237-s238. DOI: 10.1016/j.biopsych.2021.02.596.
- Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran ProgramStein MB, Levey DF, Cheng Z, Wendt FR, Harrington K, Pathak GA, Cho K, Quaden R, Radhakrishnan K, Girgenti MJ, Ho YA, Posner D, Aslan M, Duman RS, Zhao H, Polimanti R, Concato J, Gelernter J. Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Program. Nature Genetics 2021, 53: 174-184. PMID: 33510476, PMCID: PMC7972521, DOI: 10.1038/s41588-020-00767-x.
- S173. GENOME-WIDE ASSOCIATION STUDIES OF SCHIZOPHRENIA AND BIPOLAR DISORDER IN A DIVERSE COHORT OF US VETERANSBigdeli T, Fanous A, Rajeevan N, Sayward F, Li Y, Brophy M, Pyarajan S, Gleason T, Przygodszki R, Gaziano M, O’Leary T, Muralidhar S, , Huang G, Concato J, Siever L, Aslan M, Harvey P. S173. GENOME-WIDE ASSOCIATION STUDIES OF SCHIZOPHRENIA AND BIPOLAR DISORDER IN A DIVERSE COHORT OF US VETERANS. Schizophrenia Bulletin 2020, 46: s103-s103. PMCID: PMC7234483, DOI: 10.1093/schbul/sbaa031.239.
- Genome-Wide Association Studies of Schizophrenia and Bipolar Disorder in a Diverse Cohort of US VeteransBigdeli T, Fanous A, Li Y, Rajeevan N, Sayward F, Investigators G, Zhao H, Brophy M, Pyarajan S, O'Leary T, Gleason T, Przygodszki R, Muralidhar S, Gaziano J, Program M, Concato J, Siever L, Aslan M, Harvey P. Genome-Wide Association Studies of Schizophrenia and Bipolar Disorder in a Diverse Cohort of US Veterans. Biological Psychiatry 2020, 87: s178. DOI: 10.1016/j.biopsych.2020.02.468.
- Reproducible Genetic Risk Loci for Anxiety: Results From ∼200,000 Participants in the Million Veteran ProgramLevey DF, Gelernter J, Polimanti R, Zhou H, Cheng Z, Aslan M, Quaden R, Concato J, Radhakrishnan K, Bryois J, Sullivan PF, Stein M. Reproducible Genetic Risk Loci for Anxiety: Results From ∼200,000 Participants in the Million Veteran Program. American Journal Of Psychiatry 2020, 177: 223-232. PMID: 31906708, PMCID: PMC7869502, DOI: 10.1176/appi.ajp.2019.19030256.
- SHARED CONTRIBUTIONS OF COMMON GENETIC VARIANTS TO RISK OF PSYCHOSIS AMONG INDIVIDUALS OF AFRICAN, LATINO, AND EUROPEAN ANCESTRYBigdeli T, Aslan M, Genovese G, Iyegbe C, Charney A, Schooler N, on the Genetics of Schizophrenia C, Cohort G, Program M, Braff D, Muralidhar S, McCarroll S, Gaziano M, Pato M, Pato C, Harvey P, Fanous A. SHARED CONTRIBUTIONS OF COMMON GENETIC VARIANTS TO RISK OF PSYCHOSIS AMONG INDIVIDUALS OF AFRICAN, LATINO, AND EUROPEAN ANCESTRY. European Neuropsychopharmacology 2019, 29: s23-s24. DOI: 10.1016/j.euroneuro.2019.07.047.
- GENOMICS OF SUICIDAL IDEATION AND BEHAVIOR IN VETERANS WITH SEVERE MENTAL ILLNESSHarvey P, Bigdeli T, Fanous A, Aslan M, Sun N, Zhao H. GENOMICS OF SUICIDAL IDEATION AND BEHAVIOR IN VETERANS WITH SEVERE MENTAL ILLNESS. European Neuropsychopharmacology 2019, 29: s34. DOI: 10.1016/j.euroneuro.2019.07.069.
- GWAS OF A QUANTITATIVE ANXIETY TRAIT IN THE MILLION VETERAN PROGRAM SAMPLEGelernter J, Levey D, Polimanti R, Zhou H, Cheng Z, Aslan M, Quaden R, Concato J, Radhakrishnan K, Bryois J, Sullivan P, Stein M. GWAS OF A QUANTITATIVE ANXIETY TRAIT IN THE MILLION VETERAN PROGRAM SAMPLE. European Neuropsychopharmacology 2019, 29: s33. DOI: 10.1016/j.euroneuro.2019.07.067.
- GENOMIC CHARACTERIZATION OF POSTTRAUMATIC STRESS DISORDER IN A LARGE (N) MULTI-POPULATION U.S. MILITARY VETERAN SAMPLEStein M, Levey D, Polimanti R, Cheng Z, Harrington K, Radhakrishnan K, Aslan M, Concato J, Group M, Gelernter J. GENOMIC CHARACTERIZATION OF POSTTRAUMATIC STRESS DISORDER IN A LARGE (N) MULTI-POPULATION U.S. MILITARY VETERAN SAMPLE. European Neuropsychopharmacology 2019, 29: s43. DOI: 10.1016/j.euroneuro.2019.07.085.
- 54 GENOME-WIDE ASSOCATIONS WITH DEPRESSIVE SYMPTOMS IN THE MILLION VETERANS PROGRAMLevey D, Gelernter J, Polimanti R, Zhou H, Cheng Z, Aslan M, Quaden R, Harrington K, Cho K, Concato J, Radhakrishnan K, Program M, Stein M. 54 GENOME-WIDE ASSOCATIONS WITH DEPRESSIVE SYMPTOMS IN THE MILLION VETERANS PROGRAM. European Neuropsychopharmacology 2019, 29: s89. DOI: 10.1016/j.euroneuro.2019.07.195.
- Genome-wide association study of post-traumatic stress disorder reexperiencing symptoms in >165,000 US veteransGelernter J, Sun N, Polimanti R, Pietrzak R, Levey DF, Bryois J, Lu Q, Hu Y, Li B, Radhakrishnan K, Aslan M, Cheung KH, Li Y, Rajeevan N, Sayward F, Harrington K, Chen Q, Cho K, Pyarajan S, Sullivan PF, Quaden R, Shi Y, Hunter-Zinck H, Gaziano JM, Concato J, Zhao H, Stein MB. Genome-wide association study of post-traumatic stress disorder reexperiencing symptoms in >165,000 US veterans. Nature Neuroscience 2019, 22: 1394-1401. PMID: 31358989, PMCID: PMC6953633, DOI: 10.1038/s41593-019-0447-7.
- S93. GENOMICS OF SUICIDAL IDEATION AND BEHAVIOR IN VETERANS WITH SCHIZOPHRENIA AND BIPOLAR ILLNESSHarvey P, Aslan M, Sun N, Zhao H, Concato J. S93. GENOMICS OF SUICIDAL IDEATION AND BEHAVIOR IN VETERANS WITH SCHIZOPHRENIA AND BIPOLAR ILLNESS. Schizophrenia Bulletin 2019, 45: s342-s342. PMCID: PMC6455790, DOI: 10.1093/schbul/sbz020.638.
- Genome-wide Association Study of Maximum Habitual Alcohol Intake in >140,000 U.S. European and African American Veterans Yields Novel Risk LociGelernter J, Sun N, Polimanti R, Pietrzak RH, Levey DF, Lu Q, Hu Y, Li B, Radhakrishnan K, Aslan M, Cheung KH, Li Y, Rajeevan N, Sayward F, Harrington K, Chen Q, Cho K, Honerlaw J, Pyarajan S, Lencz T, Quaden R, Shi Y, Hunter-Zinck H, Gaziano JM, Kranzler HR, Concato J, Zhao H, Stein MB, Program D, Program M. Genome-wide Association Study of Maximum Habitual Alcohol Intake in >140,000 U.S. European and African American Veterans Yields Novel Risk Loci. Biological Psychiatry 2019, 86: 365-376. PMID: 31151762, PMCID: PMC6919570, DOI: 10.1016/j.biopsych.2019.03.984.
- M25 GENETICS OF COGNITIVE FUNCTION IN SCHIZOPHRENIA AND BIPOLAR DISORDERHarvey P, Sun N, Lu Q, Hu Y, Li B, Chen Q, Aslan M, Radhakrishnan K, Cheung K, Li Y, Sayward F, Rajeevan N, Zhao H, Gaziano M, Concato J. M25 GENETICS OF COGNITIVE FUNCTION IN SCHIZOPHRENIA AND BIPOLAR DISORDER. European Neuropsychopharmacology 2019, 29: s967-s968. DOI: 10.1016/j.euroneuro.2017.08.332.
- STUDIES ON ALCOHOL DEPENDENCE GENETICS FROM YALE-PENN AND THE MVPGelernter J, Sun N, Polimanti R, Zhou H, Levey D, Harrington K, Gaziano M, Pyarajan S, Aslan M, Sayward F, Li B, Farrer L, Zhao H, Concato J, Stein M. STUDIES ON ALCOHOL DEPENDENCE GENETICS FROM YALE-PENN AND THE MVP. European Neuropsychopharmacology 2019, 29: s1035-s1036. DOI: 10.1016/j.euroneuro.2018.07.032.
- Correction: Prolonged Grief Disorder: Psychometric Validation of Criteria Proposed for DSM-V and ICD-11Prigerson H, Horowitz M, Jacobs S, Parkes C, Aslan M, Goodkin K, Raphael B, Marwit S, Wortman C, Neimeyer R, Bonanno G, Block S, Kissane D, Boelen P, Maercker A, Litz B, Johnson J, First M, Maciejewski P. Correction: Prolonged Grief Disorder: Psychometric Validation of Criteria Proposed for DSM-V and ICD-11. PLOS Medicine 2013, 10: 10.1371/annotation/a1d91e0d-981f-4674-926c-0fbd2463b5ea. PMCID: PMC3867550, DOI: 10.1371/annotation/a1d91e0d-981f-4674-926c-0fbd2463b5ea.
- Design of “Neuropsychological and Mental Health Outcomes of Operation Iraqi Freedom: A Longitudinal Cohort Study”Aslan M, Concato J, Peduzzi P, Proctor S, Schnurr P, Marx B, McFall M, Gleason T, Huang G, Vasterling J. Design of “Neuropsychological and Mental Health Outcomes of Operation Iraqi Freedom: A Longitudinal Cohort Study”. Journal Of Investigative Medicine 2013, 61: 569. DOI: 10.231/jim.0b013e31828407ff.
- Changes in Gleason Scores for Prostate CancerRamos J, Uchio E, Aslan M, Concato J. Changes in Gleason Scores for Prostate Cancer. Journal Of Investigative Medicine 2010, 58: 625. DOI: 10.2310/jim.0b013e3181d4720c.
- Asymptotically minimax Bayes predictive densitiesAslan M. Asymptotically minimax Bayes predictive densities. Annals of Statistics 2006; 34:2921-2938.
- Validity of Using an Electronic Medical Record for Assessing Quality of Care in an Outpatient SettingBenin AL, Vitkauskas G, Thornquist E, Shapiro ED, Concato J, Aslan M, Krumholz HM. Validity of Using an Electronic Medical Record for Assessing Quality of Care in an Outpatient Setting. Medical Care 2005, 43: 691-698. PMID: 15970784, DOI: 10.1097/01.mlr.0000167185.26058.8e.
- Childhood maltreatment as a risk factor for adult cardiovascular disease and depression.Batten SV, Aslan M, Maciejewski PK, Mazure CM. Childhood maltreatment as a risk factor for adult cardiovascular disease and depression. The Journal Of Clinical Psychiatry 2004, 65: 249-54. PMID: 15003081, DOI: 10.4088/jcp.v65n0217.
- Double-Blind, Placebo-Controlled Assessment of Combined Clonazepam With Paroxetine Compared With Paroxetine Monotherapy for Generalized Social Anxiety DisorderBatten S, Aslan M, Maciejewski P, Mazure C. Double-Blind, Placebo-Controlled Assessment of Combined Clonazepam With Paroxetine Compared With Paroxetine Monotherapy for Generalized Social Anxiety Disorder. The Journal Of Clinical Psychiatry 2004, 65: 104-109. DOI: 10.4088/jcp.v65n0216.
- A Generalized Maximum Likelihood PriorAslan M, Nicolaou A. A Generalized Maximum Likelihood Prior. American Statistical Association Proceedings of the Section on Bayesian Statistical Science 2005;15-18.