Kelly Olino, MD, FACS
Assistant Professor of Surgery (Oncology); Leader, Skin Cancer Surgery, Melanoma Program; Clinical Director of the Smilow Melanoma Program, Yale Cancer Center; Co-Director Cutaneous Malignancy Tumor Board, Yale Cancer Center; Medical Student Clerkship Liaison for Division of Surgical Oncology, Surgery
Research & Publications
Biography
News
Research Summary
Dr. Olino works closely with both basic science researchers and her colleagues in medical oncology to perform translational research and in developing clinical trials to utilize immune therapies to treat skin and soft tissue cancers including melanoma, merkel cell carcinoma and sarcoma.
Extensive Research Description
Tumor immunology
Coauthors
Research Interests
Carcinoma, Squamous Cell; Immunotherapy; Melanoma; Soft Tissue Neoplasms; Carcinoma, Merkel Cell; Adrenocortical Carcinoma; Surgical Oncology
Selected Publications
- Impact of COVID-19 on the gastrointestinal surgical oncology patient populationBakkila B, Bakkila B, Marks V, Marks V, Kerekes D, Kunstman J, Kunstman J, Salem R, Salem R, Billingsley K, Ahuja N, Ahuja N, Laurans M, Laurans M, Olino K, Olino K, Khan S. Impact of COVID-19 on the gastrointestinal surgical oncology patient population. Heliyon 2023, 9: e18459. DOI: 10.1016/j.heliyon.2023.e18459.
- Combinatorial immunotherapy with agonistic CD40 activates dendritic cells to express IL12 and overcomes PD-1 resistance.Krykbaeva I, Bridges K, Damsky W, Pizzurro G, Alexander A, McGeary M, Park K, Muthusamy V, Eyles J, Eyles J, Luheshi N, Turner N, Weiss S, Olino K, Kaech S, Kluger H, Miller-Jensen K, Bosenberg M. Combinatorial immunotherapy with agonistic CD40 activates dendritic cells to express IL12 and overcomes PD-1 resistance. Cancer Immunology Research 2023, of1-of19. PMID: 37478171, DOI: 10.1158/2326-6066.cir-22-0699.
- Impact of COVID-19 on the gastrointestinal surgical oncology patient populationBakkila B, Marks V, Kerekes D, Kunstman J, Salem R, Billingsley K, Ahuja N, Laurans M, Olino K, Khan S. Impact of COVID-19 on the gastrointestinal surgical oncology patient population. Heliyon 2023, 9: e18459. PMID: 37534012, PMCID: PMC10391949, DOI: 10.1016/j.heliyon.2023.e18459.
- Case report: Metastatic Merkel cell carcinoma presenting seven years after loco-regional disease resection of primary tumor with interval in-transit and nodal metastasesRusheen J, Clune J, Ariyan S, Baumann R, Kluger H, Olino K, Weiss S. Case report: Metastatic Merkel cell carcinoma presenting seven years after loco-regional disease resection of primary tumor with interval in-transit and nodal metastases. Frontiers In Oncology 2023, 13: 1217816. PMID: 37476373, PMCID: PMC10354444, DOI: 10.3389/fonc.2023.1217816.
- Efficacy of adjuvant therapy in patients (pts) with AJCC v8 stage IIIA cutaneous melanoma.Grover P, Li I, Kuijpers A, Kreidieh F, Williamson A, Amaral T, Dimitriou F, Placzke J, Olino K, Vitale M, Saiag P, Gutzmer R, Allayous C, Olofsson Bagge R, Asher N, Meniawy T, Lawless A, Warburton L, Menzies A, Long G. Efficacy of adjuvant therapy in patients (pts) with AJCC v8 stage IIIA cutaneous melanoma. Journal Of Clinical Oncology 2023, 41: 9518-9518. DOI: 10.1200/jco.2023.41.16_suppl.9518.
- The role of imaging and sentinel lymph node biopsy in patients with T3b-T4b melanoma with clinically negative diseasePapageorge M, Maina R, King A, Lee V, Baumann R, Pucar D, Ariyan S, Khan S, Weiss S, Clune J, Olino K. The role of imaging and sentinel lymph node biopsy in patients with T3b-T4b melanoma with clinically negative disease. Frontiers In Oncology 2023, 13: 1143354. PMID: 37223678, PMCID: PMC10200883, DOI: 10.3389/fonc.2023.1143354.
- Lenvatinib or anti-VEGF in combination with anti-PD-1 differentially augments anti-tumor activity in melanomaTran T, Caulfield J, Zhang L, Schoenfeld D, Djureinovic D, Chiang V, Oria V, Weiss S, Olino K, Jilaveanu L, Kluger H. Lenvatinib or anti-VEGF in combination with anti-PD-1 differentially augments anti-tumor activity in melanoma. JCI Insight 2023, 8: e157347. PMID: 36821392, PMCID: PMC10132152, DOI: 10.1172/jci.insight.157347.
- Evaluating the medical management of locally advanced and metastatic basal cell carcinoma: A single institutional retrospective analysis investigating efficacy, safety, and tolerabilityBelzer A, Pach J, Mortlock R, Clune J, Olino K, Sznol M, Bhatia A, Burtness B, Christensen S, Leventhal J. Evaluating the medical management of locally advanced and metastatic basal cell carcinoma: A single institutional retrospective analysis investigating efficacy, safety, and tolerability. JAAD International 2023, 11: 174-175. PMID: 37252181, PMCID: PMC10213716, DOI: 10.1016/j.jdin.2023.02.007.
- Malignant Melanoma in Older Adults: Different Patient or Different Disease?Sasson D, Smetona J, Parsaei Y, Papageorge M, Ariyan S, Olino K, Clune J. Malignant Melanoma in Older Adults: Different Patient or Different Disease? Cureus 2023, 15: e34742. PMCID: PMC9998075, DOI: 10.7759/cureus.34742.
- Malignant Melanoma in Older Adults: Different Patient or Different Disease?Sasson D, Smetona J, Parsaei Y, Papageorge M, Ariyan S, Olino K, Clune J. Malignant Melanoma in Older Adults: Different Patient or Different Disease? Cureus 2023, 15: e34742. PMID: 36909026, PMCID: PMC9998075, DOI: 10.7759/cureus.34742.
- Evaluating the Medical Management of Locally Advanced and Metastatic Basal Cell Carcinoma: A Single Institutional Retrospective Analysis Investigating Efficacy, Safety, and TolerabilityBelzer A, Pach J, Mortlock R, Clune J, Olino K, Sznol M, Bhatia A, Burtness B, Christensen S, Leventhal J. Evaluating the Medical Management of Locally Advanced and Metastatic Basal Cell Carcinoma: A Single Institutional Retrospective Analysis Investigating Efficacy, Safety, and Tolerability. JAAD International 2023 DOI: 10.1016/j.jdin.2023.02.007.
- Predictive accuracy of elevated mitotic rate on lymph node positivity and recurrence in thin melanomasLy C, Blaha O, Wei W, Galan A, Kluger H, Ariyan S, Olino K, Clune J. Predictive accuracy of elevated mitotic rate on lymph node positivity and recurrence in thin melanomas. Frontiers In Oncology 2023, 12: 1077226. DOI: 10.3389/fonc.2022.1077226.
- Predictive accuracy of elevated mitotic rate on lymph node positivity and recurrence in thin melanomasLy C, Blaha O, Wei W, Galan A, Kluger H, Ariyan S, Olino K, Clune J. Predictive accuracy of elevated mitotic rate on lymph node positivity and recurrence in thin melanomas. Frontiers In Oncology 2023, 12: 1077226. PMID: 36686728, PMCID: PMC9853390, DOI: 10.3389/fonc.2022.1077226.
- Current diagnosis and management of cardiac melanoma: a case series and reviewLong A, Chang J, Glahn J, Olino K, Tran T, Clune J. Current diagnosis and management of cardiac melanoma: a case series and review. Journal Of Cancer Metastasis And Treatment 2023 DOI: 10.20517/2394-4722.2022.113.
- The spectrum of cutaneous immune-related adverse events in patients with skin of colorBelzer A, Mortlock R, Olamiju B, Olino K, Cohen J, Leventhal J. The spectrum of cutaneous immune-related adverse events in patients with skin of color. Journal Of The American Academy Of Dermatology 2022, 88: 1156-1158. PMID: 36470309, DOI: 10.1016/j.jaad.2022.11.051.
- Unmeasured factors are associated with the use of completion lymph node dissection (CLND) in melanomaLeonard L, Beaty L, Thomas M, Quinn C, Colborn K, Araujo T, Torphy R, Assumpção L, Olino K, Studts C, Franco S, McCarter M, Stewart C, Gleisner A. Unmeasured factors are associated with the use of completion lymph node dissection (CLND) in melanoma. Journal Of Surgical Oncology 2022, 127: 716-726. PMID: 36453464, DOI: 10.1002/jso.27153.
- Indoor Versus Outdoor: Does Occupational Sunlight Exposure Increase Melanoma Risk? A Systematic ReviewMaduka R, Tai K, Gonsai R, DeWalt N, Chetty A, Brackett A, Olino K, Schneider E, Ahuja V. Indoor Versus Outdoor: Does Occupational Sunlight Exposure Increase Melanoma Risk? A Systematic Review. Journal Of Surgical Research 2022, 283: 274-281. PMID: 36423476, DOI: 10.1016/j.jss.2022.10.025.
- The Role of Preoperative Imaging in the Management of High-Risk MelanomaPapageorge M, Maina R, King A, Lee V, Baumann R, Ariyan S, Khan S, Clune J, Olino K. The Role of Preoperative Imaging in the Management of High-Risk Melanoma. Journal Of The American College Of Surgeons 2022, 235: s257-s257. DOI: 10.1097/01.xcs.0000895024.53746.fb.
- Integrative molecular and clinical profiling of acral melanoma links focal amplification of 22q11.21 to metastasisFarshidfar F, Rhrissorrakrai K, Levovitz C, Peng C, Knight J, Bacchiocchi A, Su J, Yin M, Sznol M, Ariyan S, Clune J, Olino K, Parida L, Nikolaus J, Zhang M, Zhao S, Wang Y, Huang G, Wan M, Li X, Cao J, Yan Q, Chen X, Newman AM, Halaban R. Integrative molecular and clinical profiling of acral melanoma links focal amplification of 22q11.21 to metastasis. Nature Communications 2022, 13: 898. PMID: 35197475, PMCID: PMC8866401, DOI: 10.1038/s41467-022-28566-4.
- ASO Visual Abstract: Merkel Cell Carcinoma-Changing Practice Patterns and Impact on Recurrence-Free and Overall Survival at a Single Institution and Nationally.Esposito A, Jacobs D, Ariyan S, Galan A, Kluger H, Clune J, Weiss S, Tran T, Olino K. ASO Visual Abstract: Merkel Cell Carcinoma-Changing Practice Patterns and Impact on Recurrence-Free and Overall Survival at a Single Institution and Nationally. Annals Of Surgical Oncology 2021, 28: 736-737. PMID: 34564774, DOI: 10.1245/s10434-021-10784-7.
- Methods of Sentinel Lymph Node Identification in Auricular MelanomaNoorbakhsh S, Papageorge M, Maina RM, Baumann R, Moores C, Weiss SA, Pucar D, Ariyan S, Olino K, Clune J. Methods of Sentinel Lymph Node Identification in Auricular Melanoma. Plastic & Reconstructive Surgery Global Open 2021, 9: e4004. PMID: 34938645, PMCID: PMC8687720, DOI: 10.1097/gox.0000000000004004.
- Squamous cell carcinoma arising in long-standing necrobiosis lipoidica treated with radical resection and split-thickness skin graftXie CB, Ring N, Damsky W, McNiff JM, Olino K, Odell I. Squamous cell carcinoma arising in long-standing necrobiosis lipoidica treated with radical resection and split-thickness skin graft. JAAD Case Reports 2021, 19: 90-93. PMID: 35024397, PMCID: PMC8724883, DOI: 10.1016/j.jdcr.2021.11.005.
- S3112 A Rare Case of Gastric Adenocarcinoma in a Patient With Graves’ DiseaseManno G, Sood A, Venkatesan R, Belalcazar L, Suimin Q, Olino K, Parupudi S. S3112 A Rare Case of Gastric Adenocarcinoma in a Patient With Graves’ Disease. The American Journal Of Gastroenterology 2021, 116: s1284-s1285. DOI: 10.14309/01.ajg.0000785980.36265.83.
- ASO Visual Abstract: Merkel Cell Carcinoma—Changing Practice Patterns and Impact on Recurrence-Free and Overall Survival at a Single Institution and NationallyEsposito A, Jacobs D, Ariyan S, Galan A, Kluger H, Clune J, Weiss S, Tran T, Olino K. ASO Visual Abstract: Merkel Cell Carcinoma—Changing Practice Patterns and Impact on Recurrence-Free and Overall Survival at a Single Institution and Nationally. Annals Of Surgical Oncology 2021, 28: 736-737. DOI: 10.1245/s10434-021-10784-7.
- ASO Author Reflections: The Utility of Overall Survival as an Outcome in the Study of Merkel Cell CarcinomaEsposito AC, Jacobs D, Olino K. ASO Author Reflections: The Utility of Overall Survival as an Outcome in the Study of Merkel Cell Carcinoma. Annals Of Surgical Oncology 2021, 29: 425-426. PMID: 34523003, DOI: 10.1245/s10434-021-10791-8.
- Merkel Cell Carcinoma: Changing Practice Patterns and Impact on Recurrence-Free and Overall Survival at a Single Institution and NationallyEsposito A, Jacobs D, Ariyan S, Galan A, Kluger H, Clune J, Weiss S, Tran T, Olino K. Merkel Cell Carcinoma: Changing Practice Patterns and Impact on Recurrence-Free and Overall Survival at a Single Institution and Nationally. Annals Of Surgical Oncology 2021, 29: 415-424. PMID: 34494169, PMCID: PMC8677689, DOI: 10.1245/s10434-021-10727-2.
- Epigenetic signatures differentiate uterine and soft tissue leiomyosarcomaHasan NM, Sharma A, Ruzgar NM, Deshpande H, Olino K, Khan S, Ahuja N. Epigenetic signatures differentiate uterine and soft tissue leiomyosarcoma. Oncotarget 2021, 12: 1566-1579. PMID: 34381562, PMCID: PMC8351604, DOI: 10.18632/oncotarget.28032.
- Circulating clonally expanded T cells reflect functions of tumor-infiltrating T cellsLucca LE, Axisa PP, Lu B, Harnett B, Jessel S, Zhang L, Raddassi K, Zhang L, Olino K, Clune J, Singer M, Kluger HM, Hafler DA. Circulating clonally expanded T cells reflect functions of tumor-infiltrating T cells. Journal Of Experimental Medicine 2021, 218: e20200921. PMID: 33651881, PMCID: PMC7933991, DOI: 10.1084/jem.20200921.
- Metabolism of Innate Immune Cells in CancerTalty R, Olino K. Metabolism of Innate Immune Cells in Cancer. Cancers 2021, 13: 904. PMID: 33670082, PMCID: PMC7927092, DOI: 10.3390/cancers13040904.
- Assessment of Age, Period, and Birth Cohort Effects and Trends in Merkel Cell Carcinoma Incidence in the United StatesJacobs D, Huang H, Olino K, Weiss S, Kluger H, Judson BL, Zhang Y. Assessment of Age, Period, and Birth Cohort Effects and Trends in Merkel Cell Carcinoma Incidence in the United States. JAMA Dermatology 2021, 157: 59-65. PMID: 33146688, PMCID: PMC7643047, DOI: 10.1001/jamadermatol.2020.4102.
- Primary Treatment Selection for Clinically Node-Negative Merkel Cell Carcinoma of the Head and NeckJacobs D, Olino K, Park HS, Clune J, Cheraghlou S, Girardi M, Burtness B, Kluger H, Judson BL. Primary Treatment Selection for Clinically Node-Negative Merkel Cell Carcinoma of the Head and Neck. Otolaryngology 2020, 164: 1214-1221. PMID: 33079010, DOI: 10.1177/0194599820967001.
- S1414 Successful Endoscopic Management of Necrotizing Pancreatitis Due to Rare Anatomical VariantsBaliss M, Nguyen C, Houghton T, Rachapudi S, Parupudi S, Olino K. S1414 Successful Endoscopic Management of Necrotizing Pancreatitis Due to Rare Anatomical Variants. The American Journal Of Gastroenterology 2020, 115: s694-s694. DOI: 10.14309/01.ajg.0000707704.50102.3e.
- Neoadjuvant anti–programmed cell death 1 therapy for locally advanced basal cell carcinoma in treatment-naive patients: A case seriesLigtenberg KG, Hu JK, Damsky W, Olino K, Kluger H, Clune J, Cowper SE, Panse G, Leventhal J, Weiss SA. Neoadjuvant anti–programmed cell death 1 therapy for locally advanced basal cell carcinoma in treatment-naive patients: A case series. JAAD Case Reports 2020, 6: 628-633. PMID: 32613057, PMCID: PMC7317689, DOI: 10.1016/j.jdcr.2020.05.010.
- Assessment of Lymph Node Evaluation in Patients with Clinically Node Negative Merkel Cell Carcinoma of the Head and NeckJacobs D, Park H, Young M, Olino K, Rahmati R, Mehra S, Burtness B, Judson B. Assessment of Lymph Node Evaluation in Patients with Clinically Node Negative Merkel Cell Carcinoma of the Head and Neck. International Journal Of Radiation Oncology • Biology • Physics 2020, 106: 1191-1192. DOI: 10.1016/j.ijrobp.2019.11.099.
- Survival after checkpoint inhibitors for metastatic acral, mucosal and uveal melanomaKlemen ND, Wang M, Rubinstein JC, Olino K, Clune J, Ariyan S, Cha C, Weiss SA, Kluger HM, Sznol M. Survival after checkpoint inhibitors for metastatic acral, mucosal and uveal melanoma. Journal For ImmunoTherapy Of Cancer 2020, 8: e000341. PMID: 32209601, PMCID: PMC7103823, DOI: 10.1136/jitc-2019-000341.
- Exposing Hidden Targets: Combining epigenetic and immunotherapy to overcome cancer resistanceOlino K, Park T, Ahuja N. Exposing Hidden Targets: Combining epigenetic and immunotherapy to overcome cancer resistance. Seminars In Cancer Biology 2020, 65: 114-122. PMID: 31911188, DOI: 10.1016/j.semcancer.2020.01.001.
- Measurement of 2-hydroxyglutarate enantiomers in serum by chiral gas chromatography-tandem mass spectrometry and its application as a biomarker for IDH mutant gliomas.Strain SK, Groves MD, Olino KL, Emmett MR. Measurement of 2-hydroxyglutarate enantiomers in serum by chiral gas chromatography-tandem mass spectrometry and its application as a biomarker for IDH mutant gliomas. Clinical Mass Spectrometry. Jan 2020 Jan; 15(4), 16-20.
- Measurement of 2-hydroxyglutarate enantiomers in serum by chiral gas chromatography-tandem mass spectrometry and its application as a biomarker for IDH mutant gliomasStrain S, Groves M, Olino K, Emmett M. Measurement of 2-hydroxyglutarate enantiomers in serum by chiral gas chromatography-tandem mass spectrometry and its application as a biomarker for IDH mutant gliomas. Journal Of Mass Spectrometry And Advances In The Clinical Lab 2020, 15: 16-24. DOI: 10.1016/j.clinms.2019.11.002.
- PD-1 Blockade in Advanced Adrenocortical Carcinoma.Raj N, Zheng Y, Kelly V, Katz SS, Chou J, Do RKG, Capanu M, Zamarin D, Saltz LB, Ariyan CE, Untch BR, O'Reilly EM, Gopalan A, Berger MF, Olino K, Segal NH, Reidy-Lagunes DL. PD-1 Blockade in Advanced Adrenocortical Carcinoma. Journal Of Clinical Oncology 2019, 38: 71-80. PMID: 31644329, PMCID: PMC7351334, DOI: 10.1200/jco.19.01586.
- 2805 Targeted Interventions Improving Compliance With Guideline-Based Care in Acute PancreatitisSydor M, Roark R, Samuel R, Chatila A, Nguyen B, Dayah R, Marcondes F, Khowaja T, Kaushik C, Faruqi J, Garza R, Agarwal M, Biggs S, Tambra S, Kline K, Bilal M, Olino K, Parupudi S, Sonstein L. 2805 Targeted Interventions Improving Compliance With Guideline-Based Care in Acute Pancreatitis. The American Journal Of Gastroenterology 2019, 114: s1548-s1549. DOI: 10.14309/01.ajg.0000600752.71743.ef.
- Patterns of failure after immunotherapy with checkpoint inhibitors predict durable progression-free survival after local therapy for metastatic melanomaKlemen ND, Wang M, Feingold PL, Cooper K, Pavri SN, Han D, Detterbeck FC, Boffa DJ, Khan SA, Olino K, Clune J, Ariyan S, Salem RR, Weiss SA, Kluger HM, Sznol M, Cha C. Patterns of failure after immunotherapy with checkpoint inhibitors predict durable progression-free survival after local therapy for metastatic melanoma. Journal For ImmunoTherapy Of Cancer 2019, 7: 196. PMID: 31340861, PMCID: PMC6657062, DOI: 10.1186/s40425-019-0672-3.
- Efficacy and safety of pembrolizumab in patients with advanced adrenocortical carcinoma.Raj N, Zheng Y, Kelly V, Katz S, Chou J, Do R, Capanu M, Zamarin D, Ariyan C, Untch B, O'Reilly E, Gopalan A, Berger M, Olino K, Segal N, Reidy D. Efficacy and safety of pembrolizumab in patients with advanced adrenocortical carcinoma. Journal Of Clinical Oncology 2019, 37: 4112-4112. DOI: 10.1200/jco.2019.37.15_suppl.4112.
- Prevalence of False-Negative Results of Intraoperative Consultation on Surgical Margins During Resection of Gastric and Gastroesophageal AdenocarcinomaMcAuliffe JC, Tang LH, Kamrani K, Olino K, Klimstra DS, Brennan MF, Coit DG. Prevalence of False-Negative Results of Intraoperative Consultation on Surgical Margins During Resection of Gastric and Gastroesophageal Adenocarcinoma. JAMA Surgery 2019, 154: 126-132. PMID: 30422226, PMCID: PMC6439656, DOI: 10.1001/jamasurg.2018.3863.
- Hepatic Inflammatory Pseudotumor: An Important Differential Diagnosis in Patients With a History of Previous Biliary Procedures.Zhao J, Olino K, Low LE, Qiu S, Stevenson HL. Hepatic Inflammatory Pseudotumor: An Important Differential Diagnosis in Patients With a History of Previous Biliary Procedures. ACG Case Reports Journal 2019, 6: e00015. PMID: 31598534, PMCID: PMC6657982, DOI: 10.14309/crj.0000000000000015.
- Evaluating Adherence to Guideline-Based Care in Diagnosis and Management of Acute Pancreatitis at an Academic Medical Center - A Quality Improvement ProjectKline K, Bilal M, Marcondes F, Samuel R, Joshi S, Allencherril R, Fischer W, Jenson W, Guturu P, Sonstein L, Parupudi S, Olino K. Evaluating Adherence to Guideline-Based Care in Diagnosis and Management of Acute Pancreatitis at an Academic Medical Center - A Quality Improvement Project. The American Journal Of Gastroenterology 2018, 113: s12-s13. DOI: 10.14309/00000434-201810001-00019.
- Evaluating Appropriate Use of Antibiotics in Acute Pancreatitis - Need for Antibiotic StewardshipKline K, Marcondes F, Bilal M, Joshi S, Allencherril R, Fischer W, Guturu P, Olino K, Parupudi S. Evaluating Appropriate Use of Antibiotics in Acute Pancreatitis - Need for Antibiotic Stewardship. The American Journal Of Gastroenterology 2018, 113: s618-s619. DOI: 10.14309/00000434-201810001-01074.
- Gastric Neuroendocrine Tumor Presenting as Large Gastric Ulceration and MelenaSamuel R, Tayyem O, Krill T, Abdulla H, Maharsi S, Olino K, Guturu P, Parupudi S. Gastric Neuroendocrine Tumor Presenting as Large Gastric Ulceration and Melena. The American Journal Of Gastroenterology 2018, 113: s1478. DOI: 10.14309/00000434-201810001-02654.
- Development of a Model for Training and Assessing Open Image-Guided Liver Tumor AblationDiab K, Kochat S, McClintic J, Stevenson HL, Agle SC, Olino K, Tyler DS, Brown KM. Development of a Model for Training and Assessing Open Image-Guided Liver Tumor Ablation. Journal Of Surgical Education 2018, 76: 554-559. PMID: 30121166, DOI: 10.1016/j.jsurg.2018.07.015.
- Immunologic Aspects of Regional Chemotherapeutic Treatments in MelanomaPerone J, Tamesa T, Tsutsui M, Alvarado R, Dolber P, Pinchuk I, Olino K, Tyler D. Immunologic Aspects of Regional Chemotherapeutic Treatments in Melanoma. Journal Of The American College Of Surgeons 2017, 225: s192-s193. DOI: 10.1016/j.jamcollsurg.2017.07.439.
- Autoimmune Pancreatitis Mimicking Pancreatic Cancer: It Can HappenSaraireh H, Bilal M, Qiu S, Parupudi S, Olino K. Autoimmune Pancreatitis Mimicking Pancreatic Cancer: It Can Happen. The American Journal Of Gastroenterology 2017, 112: s711-s712. DOI: 10.14309/00000434-201710001-01310.
- Multidisciplinary Management of Gastric NeoplasmsOlino K, Tyler D. Multidisciplinary Management of Gastric Neoplasms. Surgical Clinics Of North America 2017, 97: i. DOI: 10.1016/s0039-6109(17)30019-1.
- Development of laparoscopic and open models for training and assessing image-guided liver tumor ablationDiab K, Agle S, Olino K, Kochat S, Tyler D, Brown K. Development of laparoscopic and open models for training and assessing image-guided liver tumor ablation. Hepato Pancreato Biliary 2017, 19: s84-s85. DOI: 10.1016/j.hpb.2017.02.113.
- Gastric NeoplasmsOlino KL, Tyler DS. Gastric Neoplasms. Surgical Clinics Of North America 2017, 97: xv-xvi. PMID: 28325200, DOI: 10.1016/j.suc.2017.02.001.
- Palliative Care for Pancreatic and Periampullary CancerPerone JA, Riall TS, Olino K. Palliative Care for Pancreatic and Periampullary Cancer. Surgical Clinics Of North America 2016, 96: 1415-1430. PMID: 27865285, PMCID: PMC5119929, DOI: 10.1016/j.suc.2016.07.012.
- Incidence of hepaticojejunostomy stricture after hepaticojejunostomyDimou FM, Adhikari D, Mehta HB, Olino K, Riall TS, Brown KM. Incidence of hepaticojejunostomy stricture after hepaticojejunostomy. Surgery 2016, 160: 691-698. PMID: 27392391, PMCID: PMC5429863, DOI: 10.1016/j.surg.2016.05.021.
- What is the OPTiMal Way to Manage In-Transit Disease?Olino K, Tyler DS. What is the OPTiMal Way to Manage In-Transit Disease? Annals Of Surgical Oncology 2016, 23: 4126-4129. PMID: 27380046, DOI: 10.1245/s10434-016-5393-y.
- Longer Course of Induction Chemotherapy Followed by Chemoradiation Favors Better Survival Outcomes for Patients With Locally Advanced Pancreatic CancerFaisal F, Tsai HL, Blackford A, Olino K, Xia C, De Jesus-Acosta A, Le DT, Cosgrove D, Azad N, Rasheed Z, Diaz LA, Donehower R, Laheru D, Hruban RH, Fishman EK, Edil BH, Schulick R, Wolfgang C, Herman J, Zheng L. Longer Course of Induction Chemotherapy Followed by Chemoradiation Favors Better Survival Outcomes for Patients With Locally Advanced Pancreatic Cancer. American Journal Of Clinical Oncology 2016, 39: 18-26. PMID: 24351782, PMCID: PMC4061284, DOI: 10.1097/coc.0000000000000022.
- Low objective response and high toxicity to single-agent mitotane in patients with metastatic adrenocortical carcinoma (ACC): A 25 year experience at MSKCC.Lung B, Valentino E, Gerst S, Untch B, Katz S, Strong V, Raj N, Olino K, Saltz L, Reidy D. Low objective response and high toxicity to single-agent mitotane in patients with metastatic adrenocortical carcinoma (ACC): A 25 year experience at MSKCC. Journal Of Clinical Oncology 2015, 33: 4105-4105. DOI: 10.1200/jco.2015.33.15_suppl.4105.
- PD-1/PD-L1 Blockade Together With Vaccine Therapy Facilitates Effector T-Cell Infiltration Into Pancreatic TumorsSoares KC, Rucki AA, Wu AA, Olino K, Xiao Q, Chai Y, Wamwea A, Bigelow E, Lutz E, Liu L, Yao S, Anders RA, Laheru D, Wolfgang CL, Edil BH, Schulick RD, Jaffee EM, Zheng L. PD-1/PD-L1 Blockade Together With Vaccine Therapy Facilitates Effector T-Cell Infiltration Into Pancreatic Tumors. Journal Of Immunotherapy 2015, 38: 1-11. PMID: 25415283, PMCID: PMC4258151, DOI: 10.1097/cji.0000000000000062.
- Right Colectomy Procedure GuideOlino K, Samdani T, Garcia-Aguilar J. Right Colectomy Procedure Guide. 2015, 121-131. DOI: 10.1007/978-3-319-09120-4_10.
- A preclinical murine model of hepatic metastases.Soares KC, Foley K, Olino K, Leubner A, Mayo SC, Jain A, Jaffee E, Schulick RD, Yoshimura K, Edil B, Zheng L. A preclinical murine model of hepatic metastases. Journal Of Visualized Experiments 2014, 51677. PMID: 25285458, PMCID: PMC4378377, DOI: 10.3791/51677.
- A Preclinical Murine Model of Hepatic MetastasesSoares K, Foley K, Olino K, Leubner A, Mayo S, Jain A, Jaffee E, Schulick R, Yoshimura K, Edil B, Zheng L. A Preclinical Murine Model of Hepatic Metastases. Journal Of Visualized Experiments 2014 DOI: 10.3791/51677-v.
- Traumatic HemoperitoneumHicks CW, Garcia L, Howley I, Olino K, Atallah C, Sopko N, Efron D, Stevens KA. Traumatic Hemoperitoneum. JAMA Surgery 2014, 149: 615-616. PMID: 24759918, DOI: 10.1001/jamasurg.2013.123.
- A Single Institution's 26-Year Experience With Nonfunctional Pancreatic Neuroendocrine TumorsEllison TA, Wolfgang CL, Shi C, Cameron JL, Murakami P, Mun LJ, Singhi AD, Cornish TC, Olino K, Meriden Z, Choti M, Diaz LA, Pawlik TM, Schulick RD, Hruban RH, Edil BH. A Single Institution's 26-Year Experience With Nonfunctional Pancreatic Neuroendocrine Tumors. Annals Of Surgery 2014, 259: 204-212. PMID: 23673766, PMCID: PMC4048026, DOI: 10.1097/sla.0b013e31828f3174.
- Missing Consent Forms in the Preoperative Area: A Single-Center Assessment of the Scope of the Problem and Its Downstream EffectsGaronzik-Wang JM, Brat G, Salazar JH, Dhanasopon A, Lin A, Akinkuotu A, O’Daly A, Elder B, Olino K, Burns W, Camp M, Lipsett PA, Freischlag JA, Haut ER. Missing Consent Forms in the Preoperative Area: A Single-Center Assessment of the Scope of the Problem and Its Downstream Effects. JAMA Surgery 2013, 148: 886-889. PMID: 23842781, DOI: 10.1001/jamasurg.2013.354.
- Abstract PR9: Granulocyte macrophage colony stimulating factor (GM-CSF) pancreas tumor vaccine in combination with blockade of PD-1 in a preclinical model of pancreatic cancer.Soares K, Olino K, Edil B, Zhou D, Wamwea A, Leubner A, Schulick R, Pardoll D, Jaffee E, Zheng L. Abstract PR9: Granulocyte macrophage colony stimulating factor (GM-CSF) pancreas tumor vaccine in combination with blockade of PD-1 in a preclinical model of pancreatic cancer. Cancer Research 2013, 73: pr9-pr9. DOI: 10.1158/1538-7445.tumimm2012-pr9.
- The intraductal injection of 5-fluorouracil for breast cancer: Preventive effect and immune response.Mori T, Wada S, Olino K, Edil B, Pardoll D, Schulick R, Sukumar S, Yoshimura K. The intraductal injection of 5-fluorouracil for breast cancer: Preventive effect and immune response. Journal Of Clinical Oncology 2012, 30: e13559-e13559. DOI: 10.1200/jco.2012.30.15_suppl.e13559.
- Glycolipid Antigens for Treating Hepatic Colorectal Cancer Metastases and Their Effect on the Therapeutic Efficacy of Live Attenuated Listeria monocytogenesOlino K, Edil BH, Meckel KF, Pan X, Thuluvath A, Pardoll DM, Schulick RD, Yoshimura K, Weber WP. Glycolipid Antigens for Treating Hepatic Colorectal Cancer Metastases and Their Effect on the Therapeutic Efficacy of Live Attenuated Listeria monocytogenes. JAMA Surgery 2012, 147: 480-482. PMID: 22785644, PMCID: PMC4144826, DOI: 10.1001/archsurg.2011.2206.
- Clinicopathological Characteristics and Molecular Analyses of Multifocal Intraductal Papillary Mucinous Neoplasms of the PancreasMatthaei H, Norris AL, Tsiatis AC, Olino K, Hong SM, dal Molin M, Goggins MG, Canto M, Horton KM, Jackson KD, Capelli P, Zamboni G, Bortesi L, Furukawa T, Egawa S, Ishida M, Ottomo S, Unno M, Motoi F, Wolfgang CL, Edil BH, Cameron JL, Eshleman JR, Schulick RD, Maitra A, Hruban RH. Clinicopathological Characteristics and Molecular Analyses of Multifocal Intraductal Papillary Mucinous Neoplasms of the Pancreas. Annals Of Surgery 2012, 255: 326-333. PMID: 22167000, PMCID: PMC3534752, DOI: 10.1097/sla.0b013e3182378a18.
- Risk Factors for the Development of Intra-Abdominal Abscess Following Splenectomy for TraumaHashmi M, Kisat M, Rehman K, Zafar S, Olino K, Haut E, Schneider E, Stevens K, Efron D, Chi A, Rushing A, Zafar H, Haider A. Risk Factors for the Development of Intra-Abdominal Abscess Following Splenectomy for Trauma. Journal Of Surgical Research 2012, 172: 200. DOI: 10.1016/j.jss.2011.11.240.
- Radiation in the management of pancreatic neuroendocrine tumors.Maidment B, Ellison T, Herman J, Sharma N, Laheru D, Regine W, Wild A, Olino K, Hruban R, Cameron J, Alexander H, Hanna N, Hausner P, Zheng L, Choti M, Schulick R, Wolfgang C, Edil B. Radiation in the management of pancreatic neuroendocrine tumors. Journal Of Clinical Oncology 2012, 30: 335-335. DOI: 10.1200/jco.2012.30.4_suppl.335.
- Tumor-Associated Antigen Expressing Listeria monocytogenes Induces Effective Primary and Memory T-Cell Responses Against Hepatic Colorectal Cancer MetastasesOlino K, Wada S, Edil BH, Pan X, Meckel K, Weber W, Slansky J, Tamada K, Lauer P, Brockstedt D, Pardoll D, Schulick R, Yoshimura K. Tumor-Associated Antigen Expressing Listeria monocytogenes Induces Effective Primary and Memory T-Cell Responses Against Hepatic Colorectal Cancer Metastases. Annals Of Surgical Oncology 2011, 19: 597-607. PMID: 21979110, PMCID: PMC4498288, DOI: 10.1245/s10434-011-2037-0.
- Conditional survival in patients with pancreatic ductal adenocarcinoma resected with curative intentMayo SC, Nathan H, Cameron JL, Olino K, Edil BH, Herman JM, Hirose K, Schulick RD, Choti MA, Wolfgang CL, Pawlik TM. Conditional survival in patients with pancreatic ductal adenocarcinoma resected with curative intent. Cancer 2011, 118: 2674-2681. PMID: 21935914, PMCID: PMC3578343, DOI: 10.1002/cncr.26553.
- Loss of E-cadherin expression and outcome among patients with resectable pancreatic adenocarcinomasHong SM, Li A, Olino K, Wolfgang CL, Herman JM, Schulick RD, Iacobuzio-Donahue C, Hruban RH, Goggins M. Loss of E-cadherin expression and outcome among patients with resectable pancreatic adenocarcinomas. Modern Pathology 2011, 24: 1237-1247. PMID: 21552209, PMCID: PMC3155013, DOI: 10.1038/modpathol.2011.74.
- Presence of Pancreatic Intraepithelial Neoplasia in the Pancreatic Transection Margin does not Influence Outcome in Patients with R0 Resected Pancreatic CancerMatthaei H, Hong SM, Mayo SC, dal Molin M, Olino K, Venkat R, Goggins M, Herman JM, Edil BH, Wolfgang CL, Cameron JL, Schulick RD, Maitra A, Hruban RH. Presence of Pancreatic Intraepithelial Neoplasia in the Pancreatic Transection Margin does not Influence Outcome in Patients with R0 Resected Pancreatic Cancer. Annals Of Surgical Oncology 2011, 18: 3493-3499. PMID: 21537863, PMCID: PMC3166423, DOI: 10.1245/s10434-011-1745-9.
- Tyrosine 23 Phosphorylation-Dependent Cell-Surface Localization of Annexin A2 Is Required for Invasion and Metastases of Pancreatic CancerZheng L, Foley K, Huang L, Leubner A, Mo G, Olino K, Edil BH, Mizuma M, Sharma R, Le DT, Anders RA, Illei PB, Van Eyk JE, Maitra A, Laheru D, Jaffee EM. Tyrosine 23 Phosphorylation-Dependent Cell-Surface Localization of Annexin A2 Is Required for Invasion and Metastases of Pancreatic Cancer. PLOS ONE 2011, 6: e19390. PMID: 21572519, PMCID: PMC3084841, DOI: 10.1371/journal.pone.0019390.
- Abstract LB-456: The intraductal injection of 5-fluorouracil induces immune response to eradicate and prevent breast cancerMori T, Wada S, Olino K, Weber W, Edil B, Meckel K, Pan X, Pardoll D, Schulick R, Sukumar S, Yoshimura K. Abstract LB-456: The intraductal injection of 5-fluorouracil induces immune response to eradicate and prevent breast cancer. Cancer Research 2011, 71: lb-456-lb-456. DOI: 10.1158/1538-7445.am2011-lb-456.
- Presence of Pancreatic Intraepithelial Neoplasia in the Pancreatic Transection Margin does not Influence Outcome in Patients with R0 Resected Pancreatic CancerMatthaei H, Hong SM, Mayo SC, dal Molin M, Olino K, Venkat R, Goggins M, Herman JM, Edil BH, Wolfgang CL, Cameron JL, Schulick RD, Maitra A, Hruban RH. Presence of Pancreatic Intraepithelial Neoplasia in the Pancreatic Transection Margin does not Influence Outcome in Patients with R0 Resected Pancreatic Cancer. Indian Journal Of Surgical Oncology 2011, 2: 9-15. PMID: 22696140, PMCID: PMC3373004, DOI: 10.1007/s13193-011-0073-7.
- EUS is still superior to multidetector computerized tomography for detection of pancreatic neuroendocrine tumorsKhashab MA, Yong E, Lennon AM, Shin EJ, Amateau S, Hruban RH, Olino K, Giday S, Fishman EK, Wolfgang CL, Edil BH, Makary M, Canto MI. EUS is still superior to multidetector computerized tomography for detection of pancreatic neuroendocrine tumors. Gastrointestinal Endoscopy 2010, 73: 691-696. PMID: 21067742, DOI: 10.1016/j.gie.2010.08.030.
- The Effect of Steatosis on Echogenicity of Colorectal Liver Metastases on Intraoperative Ultrasonographyvan Vledder MG, Torbenson MS, Pawlik TM, Boctor EM, Hamper UM, Olino K, Choti MA. The Effect of Steatosis on Echogenicity of Colorectal Liver Metastases on Intraoperative Ultrasonography. JAMA Surgery 2010, 145: 661-667. PMID: 20644129, DOI: 10.1001/archsurg.2010.124.
- W1682 Tumor Size Correlates With Lymph Node Metastasis in Primary Pancreatic Endocrine NeoplasmsEllison T, Olino K, Cameron J, Hruban R, Shi C, Gilson M, Choti M, Pawlik T, Schulick R, Wolfgang C, Edil B. W1682 Tumor Size Correlates With Lymph Node Metastasis in Primary Pancreatic Endocrine Neoplasms. Gastroenterology 2010, 138: s-902-s-903. DOI: 10.1016/s0016-5085(10)64171-6.
- Immuno- and gene-therapeutic strategies targeted against cancer (mainly focusing on pancreatic cancer)Yoshimura K, Olino K, Edil BH, Schulick RD, Oka M. Immuno- and gene-therapeutic strategies targeted against cancer (mainly focusing on pancreatic cancer). Surgery Today 2010, 40: 404-410. PMID: 20425541, DOI: 10.1007/s00595-009-4120-8.
- Abstract 2935: Modulation of immune checkpoint B7-H1/B7-DC/PD-1 interaction in combination with live attenuated Listeria monocytogenes expressing a tumor associated antigen effectively treats hepatic colorectal cancer metastasesYoshimura K, Olino K, Edil B, Wada S, Pan X, Meckel K, Pardoll D, Schulick R. Abstract 2935: Modulation of immune checkpoint B7-H1/B7-DC/PD-1 interaction in combination with live attenuated Listeria monocytogenes expressing a tumor associated antigen effectively treats hepatic colorectal cancer metastases. Cancer Research 2010, 70: 2935-2935. DOI: 10.1158/1538-7445.am10-2935.
- M1442: Endoscopic Ultrasound (EUS) Versus Multidetector CT (MDCT) for Detection of Pancreatic Neuroendocrine TumorsKhashab M, Yong E, Shin E, Amateau S, Lennon A, Olino K, Wolfgang C, Edil B, Canto M. M1442: Endoscopic Ultrasound (EUS) Versus Multidetector CT (MDCT) for Detection of Pancreatic Neuroendocrine Tumors. Gastrointestinal Endoscopy 2010, 71: ab222. DOI: 10.1016/j.gie.2010.03.442.
- Clinicopathologic Analysis of Ampullary Neoplasms in 450 Patients: Implications for Surgical Strategy and Long-Term PrognosisWinter JM, Cameron JL, Olino K, Herman JM, de Jong MC, Hruban RH, Wolfgang CL, Eckhauser F, Edil BH, Choti MA, Schulick RD, Pawlik TM. Clinicopathologic Analysis of Ampullary Neoplasms in 450 Patients: Implications for Surgical Strategy and Long-Term Prognosis. Journal Of Gastrointestinal Surgery 2009, 14: 379-387. PMID: 19911239, DOI: 10.1007/s11605-009-1080-7.
- Integrin α2 Mediates Selective Metastasis to the LiverYoshimura K, Meckel KF, Laird LS, Chia CY, Park JJ, Olino KL, Tsunedomi R, Harada T, Iizuka N, Hazama S, Kato Y, Keller JW, Thompson JM, Chang F, Romer LH, Jain A, Iacobuzio-Donahue C, Oka M, Pardoll DM, Schulick RD. Integrin α2 Mediates Selective Metastasis to the Liver. Cancer Research 2009, 69: 7320-7328. PMID: 19738067, PMCID: PMC4857201, DOI: 10.1158/0008-5472.can-09-0315.
- The Current Management of Choledochal CystsEdil BH, Olino K, Cameron JL. The Current Management of Choledochal Cysts. Advances In Surgery 2009, 43: 221-232. PMID: 19845181, DOI: 10.1016/j.yasu.2009.02.007.
- SMAD4 Gene Mutations Are Associated with Poor Prognosis in Pancreatic CancerBlackford A, Serrano OK, Wolfgang CL, Parmigiani G, Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Eshleman JR, Goggins M, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Cameron JL, Olino K, Schulick R, Winter J, Herman JM, Laheru D, Klein AP, Vogelstein B, Kinzler KW, Velculescu VE, Hruban RH. SMAD4 Gene Mutations Are Associated with Poor Prognosis in Pancreatic Cancer. Clinical Cancer Research 2009, 15: 4674-4679. PMID: 19584151, PMCID: PMC2819274, DOI: 10.1158/1078-0432.ccr-09-0227.
- Genetic Mutations Associated with Cigarette Smoking in Pancreatic CancerBlackford A, Parmigiani G, Kensler TW, Wolfgang C, Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Eshleman JR, Goggins M, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Klein A, Cameron JL, Olino K, Schulick R, Winter J, Vogelstein B, Velculescu VE, Kinzler KW, Hruban RH. Genetic Mutations Associated with Cigarette Smoking in Pancreatic Cancer. Cancer Research 2009, 69: 3681-3688. PMID: 19351817, PMCID: PMC2669837, DOI: 10.1158/0008-5472.can-09-0015.
- Preoperative Chemotherapy for Colorectal Liver Metastases: Impact on Hepatic Histology and Postoperative OutcomePawlik TM, Olino K, Gleisner AL, Torbenson M, Schulick R, Choti MA. Preoperative Chemotherapy for Colorectal Liver Metastases: Impact on Hepatic Histology and Postoperative Outcome. Journal Of Gastrointestinal Surgery 2007, 11: 860-868. PMID: 17492335, DOI: 10.1007/s11605-007-0149-4.