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Yale Insights in Cardiovascular Medicine: 2022

December 18, 2022
by Elisabeth Reitman

Trending cardiovascular-related research from the Yale School of Medicine.

Researchers from the Yale School of Medicine Section of Cardiovascular Medicine outline emerging areas of research in the cardiovascular medicine field. Current research topics include the drivers of COVID-19, clinical decision making, and health disparities. Note the results are based on Altmetric data.


Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort

Science Translational Medicine

Co-author: Michael Simons

2022 ACC Expert Consensus Decision Pathway on Cardiovascular Sequelae of COVID-19 in Adults: Myocarditis and Other Myocardial Involvement, Post-Acute Sequelae of SARS-CoV-2 Infection, and Return to Play 

Journal of the American College of Cardiology (JACC)

Co-author: Erica S. Spatz

Excess Mortality in Massachusetts During the Delta and Omicron Waves of COVID-19

JAMA: Journal of the American Medical Association

Authors: Chengan Du, Chenxue Liang, Harlan Krumholz

Uncoupling of all-cause excess mortality from COVID-19 cases in a highly vaccinated state

Lancet Infectious Diseases

Authors: Chengan Du, Chenxue Liang, Shu-Xia Li, Zhenqiu Lin, Harlan M. Krumholz

The findings suggest that the mortality toll of the omicron variant of SARS-CoV-2 was neutralized in a state where vaccination is widespread, further strengthening the case for sensible public health tactics.

Dr. Harlan M. Krumholz

Peripheral Artery Disease and COVID-19 Outcomes: Insights from the Yale DOM-CovX Registry

Current Problems in Cardiology

Authors: Kim G.Smolderen, Megan Lee, Tanima Arora, Michael Simonov, Carlos Mena-Hurtado

Clinical decision support & patient-focused information

Nudging within learning health systems: next generation decision support to improve cardiovascular care

European Heart Journal

Co-author: Tariq Ahmad

Renal effects of guideline-directed medical therapies in heart failure: a consensus document from the Heart Failure Association of the European Society of Cardiology

European Journal of Heart Failure

Co-author: Jeffrey M. Testani

Analysis of Patient-Focused Information About Left Atrial Appendage Occlusion on US Hospital Web Pages

JAMA Internal Medicine

Authors: Erica S. Spatz, Joseph Ross 

Left Atrial Appendage Occlusion Versus Oral Anticoagulation in Atrial Fibrillation A Decision Analysis

Annals of Internal Medicine

Co-author: James V. Freeman

Health disparities & outcomes research

Evaluation of Temporal Trends in Racial and Ethnic Disparities in Sleep Duration Among US Adults, 2004-2018

JAMA Network Open

Authors: Howard Forman, Karthik Murugiah, Brita Roy, Cesar Caraballo-Cordovez, Yuan Lu, Harlan M. Krumholz, Johanna Elumn, Marcella Smith, Jeph Herrin, Shiwani Mahajan

Specifically, we found that over the 15 years we analyzed, Black people had the highest prevalence of both short sleep duration [fewer than 7 hours] and long sleep duration [more than 9 hours].

Dr. César Caraballo-Cordovez

Trends in 10-Year Outcomes Among Medicare Beneficiaries Who Survived an Acute Myocardial Infarction

JAMA Cardiology

Authors: Erica Leifheit, Harlan Krumholz, Yun Wang

Basic science research

Cellular recovery after prolonged warm ischaemia of the whole body


Authors: Robert Duckrow, Mario Skarica, Madhav Menon, Albert Sinusas, Stephanie Thorn, Nenad Sestan, Gregory Tietjen, Suel-Kee Kim, Anita Huttner, Hitten Zaveri, Sudhir Perincheri, Khadija Banu, David Andrijevic, Kevin Sheth

Submitted by Elisabeth Reitman on December 09, 2022