Erica C Leifheit, PhD
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Research Scientist in Epidemiology (Chronic Diseases)
Biography
Erica Leifheit is a Research Scientist in the Department of Chronic Disease Epidemiology at Yale School of Public Health. Her research interests are in cardiovascular and cerebrovascular disease epidemiology and outcomes. Dr. Leifheit’s earlier work focused on the relationship of psychosocial factors, such as social support, depression, and stress, to patient-centered outcomes and adherence after acute myocardial infarction. Her current work centers on outcomes after stroke, using national healthcare claims data to better understand patterns in stroke care delivery and outcomes across hospitals and geographic regions. She is also involved in a number of projects that use Medicare administrative data to enhance the surveillance of patient outcomes for clinical trials and prospective registries. Dr. Leifheit received her PhD in epidemiology and public health from Yale University.
Appointments
Chronic Disease Epidemiology
Research ScientistPrimary
Other Departments & Organizations
Education & Training
- PhD
- Yale University (2010)
Research
Overview
Medical Subject Headings (MeSH)
Cardiovascular Diseases; Quality of Health Care; Quality of Life; Stroke
Research at a Glance
Yale Co-Authors
Frequent collaborators of Erica C Leifheit's published research.
Publications Timeline
A big-picture view of Erica C Leifheit's research output by year.
Research Interests
Research topics Erica C Leifheit is interested in exploring.
Harlan Krumholz, MD, SM
Gail D'Onofrio, MD, MS
Judith Lichtman, PhD, MPH
Basmah Safdar, MD, FACEP
Erica Spatz, MD, MHS
Fan Li, PhD
13Publications
927Citations
Publications
2024
Association of marital/partner status with hospital readmission among young adults with acute myocardial infarction.
Zhu C, Dreyer R, Li F, Spatz E, Caraballo C, Mahajan S, Raparelli V, Leifheit E, Lu Y, Krumholz H, Spertus J, D'Onofrio G, Pilote L, Lichtman J. Association of marital/partner status with hospital readmission among young adults with acute myocardial infarction. PLOS ONE 2024, 19: e0287949. PMID: 38277368, PMCID: PMC10817183, DOI: 10.1371/journal.pone.0287949.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsMarital/partner statusPsychosocial factorsAcute myocardial infarctionYoung adultsHospital dischargeYear of hospital dischargeYoung acute myocardial infarctionAssociated with 1.3-foldCohort of young adultsLong-term readmissionCox proportional hazards modelsStatus interactionSimilar-aged menMyocardial infarctionProportional hazards modelUnpartnered statusPatient interviewsPhysician panelCardiovascular healthHospital readmissionSocioeconomic factorsAMI survivorsSequential adjustmentCardiac readmissionMultiple imputation
2022
Trends in 1-Year Recurrent Ischemic Stroke in the US Medicare Fee-for-Service Population
Leifheit EC, Wang Y, Goldstein LB, Lichtman JH. Trends in 1-Year Recurrent Ischemic Stroke in the US Medicare Fee-for-Service Population. Stroke 2022, 53: 3338-3347. PMID: 36214126, PMCID: PMC11059192, DOI: 10.1161/strokeaha.122.039438.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsRecurrent ischemic strokeIschemic strokeRecurrence rateMedicare beneficiariesRecurrent stroke rateSecondary stroke preventionPoor general healthHigh-risk populationHigh recurrence rateService Medicare beneficiariesUS Medicare feeHighest sextileRecurrent strokeStroke preventionStroke recurrenceClinical characteristicsCohort studyGeneral healthPrincipal diagnosisStroke rateUninsured adultsCox modelMedicare feeHigh recurrenceTesting ratesTrends in 10-Year Outcomes Among Medicare Beneficiaries Who Survived an Acute Myocardial Infarction
Wang Y, Leifheit EC, Krumholz HM. Trends in 10-Year Outcomes Among Medicare Beneficiaries Who Survived an Acute Myocardial Infarction. JAMA Cardiology 2022, 7: 613-622. PMID: 35507330, PMCID: PMC9069341, DOI: 10.1001/jamacardio.2022.0662.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsRecurrent acute myocardial infarctionAcute myocardial infarctionHealth priority areasLong-term outcomesCause mortalityHazard ratioWhite patientsMyocardial infarctionMedicare feeMedicare-MedicaidService beneficiariesInitial acute myocardial infarctionTen-year mortalityShort-term outcomesDemographic subgroupsEligible patientsPatient characteristicsAMI survivorsAcute periodMean ageRecurrence rateSubgroup analysisMAIN OUTCOMEMortality riskAMI admissions
2018
Outcomes after carotid endarterectomy among elderly dual Medicare-Medicaid-eligible patients.
Leifheit EC, Wang Y, Howard G, Howard VJ, Goldstein LB, Brott TG, Lichtman JH. Outcomes after carotid endarterectomy among elderly dual Medicare-Medicaid-eligible patients. Neurology 2018, 91: e1553-e1558. PMID: 30266891, PMCID: PMC6205687, DOI: 10.1212/wnl.0000000000006380.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCarotid endarterectomyDual-eligible patientsRelative annual reductionService Medicare beneficiariesDual-eligible statusYears of ageDual-eligible beneficiariesEligible patientsCause mortalityCause readmissionClinical characteristicsIschemic strokeAdjusted analysisStudy cohortWorse outcomesMedicaid coverageMedicare beneficiariesDual eligiblesPatientsMedicaid benefitsMedicare-MedicaidMedicareOutcomesEndarterectomyHigh rateSex Differences in the Presentation and Perception of Symptoms Among Young Patients With Myocardial Infarction
Lichtman JH, Leifheit EC, Safdar B, Bao H, Krumholz HM, Lorenze NP, Daneshvar M, Spertus JA, D'Onofrio G. Sex Differences in the Presentation and Perception of Symptoms Among Young Patients With Myocardial Infarction. Circulation 2018, 137: 781-790. PMID: 29459463, PMCID: PMC5822747, DOI: 10.1161/circulationaha.117.031650.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAcute myocardial infarctionPerception of symptomsChest painCare-seeking behaviorSymptom presentationYounger patientsMyocardial infarctionST-segment elevation acute myocardial infarctionMultivariable hierarchical logistic regressionIndex AMI hospitalizationMajority of womenHierarchical logistic regressionStress/anxietyVIRGO StudyMuscle painPatient characteristicsPredominant symptomAMI symptomsPerceive symptomsProdromal symptomsPatient interviewsHeart diseasePainAMI hospitalizationUS hospitals
2017
Carotid Endarterectomy and Carotid Artery Stenting in the US Medicare Population, 1999-2014
Lichtman JH, Jones MR, Leifheit EC, Sheffet AJ, Howard G, Lal BK, Howard VJ, Wang Y, Curtis J, Brott TG. Carotid Endarterectomy and Carotid Artery Stenting in the US Medicare Population, 1999-2014. JAMA 2017, 318: 1035-1046. PMID: 28975306, PMCID: PMC5818799, DOI: 10.1001/jama.2017.12882.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsVascular risk factorsCarotid endarterectomyCarotid arteryHospital mortalityCause mortalityRevascularization ratesIschemic strokeMyocardial infarctionRisk factorsMedicare beneficiariesSerial cross-sectional analysisUnderwent carotid arteryNumber of patientsUS national trendsService Medicare beneficiariesCross-sectional analysisSymptomatic patientsSymptomatic statusUnique patientsCarotid stenosisEndarterectomyMedicare inpatientMAIN OUTCOMEMedicare feePatients
2015
Sex Differences in Cardiac Risk Factors, Perceived Risk, and Health Care Provider Discussion of Risk and Risk Modification Among Young Patients With Acute Myocardial Infarction The VIRGO Study
Leifheit-Limson EC, D’Onofrio G, Daneshvar M, Geda M, Bueno H, Spertus JA, Krumholz HM, Lichtman JH. Sex Differences in Cardiac Risk Factors, Perceived Risk, and Health Care Provider Discussion of Risk and Risk Modification Among Young Patients With Acute Myocardial Infarction The VIRGO Study. Journal Of The American College Of Cardiology 2015, 66: 1949-1957. PMID: 26515996, PMCID: PMC4628727, DOI: 10.1016/j.jacc.2015.08.859.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCardiac risk factorsAcute myocardial infarctionHealth care provider discussionsRisk modificationRisk factorsHeart diseaseHealth care providersProvider discussionsVIRGO StudyYounger patientsMyocardial infarctionCare providersSignificant cardiac risk factorsYoung AMI patientsPatients age 18Heart disease riskRisk factor prevalenceSelf-perceived riskModified Poisson regressionSex differencesFactor prevalenceAMI patientsCardiac riskSpanish hospitalsProvider feedback
2013
Preventable Readmissions Within 30 Days of Ischemic Stroke Among Medicare Beneficiaries
Lichtman JH, Leifheit-Limson EC, Jones SB, Wang Y, Goldstein LB. Preventable Readmissions Within 30 Days of Ischemic Stroke Among Medicare Beneficiaries. Stroke 2013, 44: 3429-3435. PMID: 24172581, PMCID: PMC3905749, DOI: 10.1161/strokeaha.113.003165.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPreventable readmission ratesIschemic strokePrevention Quality IndicatorsPreventable readmissionsReadmission ratesHealthcare ResearchQuality's Prevention Quality IndicatorsHospital Inpatient Quality Reporting ProgramCauses of readmissionThirty-day readmissionHigh-risk patientsPatient-level factorsRandom effects logistic regressionIschemic stroke dischargesQuality Reporting ProgramCause readmissionHospital readmissionComorbid conditionsPreventable causePrimary diagnosisReadmissionMedicare feeMedicare beneficiariesService beneficiariesMultivariate analysisPrevalence of Traditional Cardiac Risk Factors and Secondary Prevention Among Patients Hospitalized for Acute Myocardial Infarction (AMI): Variation by Age, Sex, and Race
Leifheit-Limson EC, Spertus JA, Reid KJ, Jones SB, Vaccarino V, Krumholz HM, Lichtman JH. Prevalence of Traditional Cardiac Risk Factors and Secondary Prevention Among Patients Hospitalized for Acute Myocardial Infarction (AMI): Variation by Age, Sex, and Race. Journal Of Women's Health 2013, 22: 659-666. PMID: 23841468, DOI: 10.1089/jwh.2012.3962.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsMeSH KeywordsAdultAge FactorsAgedAged, 80 and overBlack or African AmericanBody Mass IndexCounselingDiabetes Mellitus, Type 2FemaleHospitalizationHumansHypercholesterolemiaHypertensionLife StyleMaleMiddle AgedMyocardial InfarctionObesityPrevalenceProspective StudiesRisk FactorsSecondary PreventionSex FactorsSmokingSmoking CessationSocioeconomic FactorsWhite PeopleConceptsCardiac risk factorsAcute myocardial infarctionSecondary prevention effortsTraditional cardiac risk factorsLipid-lowering medicationsRisk factorsWhite patientsAMI patientsMyocardial infarctionPrevention effortsGreater risk factor burdenMultiple cardiac risk factorsRisk factor burdenYoung black patientsYoung white patientsSecondary prevention strategiesRisk factor prevalenceHigh-risk subgroupsMultiple risk factorsBlack womenAge-sex groupsOlder patientsSecondary preventionYounger patientsFactor prevalence
2012
30-Day Risk-Standardized Mortality and Readmission Rates After Ischemic Stroke in Critical Access Hospitals
Lichtman JH, Leifheit-Limson EC, Jones SB, Wang Y, Goldstein LB. 30-Day Risk-Standardized Mortality and Readmission Rates After Ischemic Stroke in Critical Access Hospitals. Stroke 2012, 43: 2741-2747. PMID: 22935397, PMCID: PMC3547601, DOI: 10.1161/strokeaha.112.665646.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsRisk-standardized mortality ratesRisk-standardized readmission ratesAnnual hospital volumeIschemic strokeReadmission ratesHospital volumeVolume quartileHighest risk-standardized mortality ratesPoor short-term outcomeMedicare beneficiaries 65 yearsService Medicare beneficiaries 65 yearsHighest volume quartileHospital volume quartilesPrimary discharge diagnosisLow-volume hospitalsShort-term outcomesBeneficiaries 65 years
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