Erica Spatz, MD, MHS
Associate Professor of Cardiology and Associate Professor of Epidemiology (Chronic Diseases)Cards
About
Research
Publications
2024
Race, Ethnicity, and Gender Differences in Patient Reported Well-Being and Cognitive Functioning Within 3 Months of Symptomatic Illness During COVID-19 Pandemic
Hill M, Huebinger R, Ebna Mannan I, Yu H, Wisk L, O’Laughlin K, Gentile N, Stephens K, Gottlieb M, Weinstein R, Koo K, Santangelo M, Saydah S, Spatz E, Lin Z, Schaeffer K, Kean E, Montoy J, Rodriguez R, Idris A, McDonald S, Elmore J, Venkatesh A. Race, Ethnicity, and Gender Differences in Patient Reported Well-Being and Cognitive Functioning Within 3 Months of Symptomatic Illness During COVID-19 Pandemic. Journal Of Racial And Ethnic Health Disparities 2024, 1-18. PMID: 39172356, DOI: 10.1007/s40615-024-02124-8.Peer-Reviewed Original ResearchPROMIS T-scoresPain interferenceBlack participantsWell-beingHealth-related quality of lifeNon-Hispanic white participantsCognitive functionMeasures of healthHealth-related qualityMethodsThis prospective cohort studyFollow-up surveyProspective cohort studyT-scoreQuality of lifeCOVID-19-related health outcomesLower well-beingPROMIS-29Physical functionHealth outcomesBaseline to 3Social participationWhite participantsCohort studyCOVID-19Sleep disturbanceThe association between prolonged SARS-CoV-2 symptoms and work outcomes
Venkatesh A, Yu H, Malicki C, Gottlieb M, Elmore J, Hill M, Idris A, Montoy J, O’Laughlin K, Rising K, Stephens K, Spatz E, Weinstein R, Group F. The association between prolonged SARS-CoV-2 symptoms and work outcomes. PLOS ONE 2024, 19: e0300947. PMID: 39074096, PMCID: PMC11285965, DOI: 10.1371/journal.pone.0300947.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 symptomsReturn to workAssociated with increased oddsAnalyzed self-reported dataNational cohort studySelf-reported dataLong COVIDCOVID-19 pandemicLost work timePublic health emergencyWork absenteeismMissed workdaysElectronic surveyEmployment statusSARS-CoV-2 infectionWell-being impactsOdds ratioWork lossCohort studyNumerous healthImpact of long COVIDCOVID-19Risk factorsThree-monthsHealth emergencyTransforming Hypertension Diagnosis and Management in The Era of Artificial Intelligence: A 2023 National Heart, Lung, and Blood Institute (NHLBI) Workshop Report.
Shimbo D, Shah R, Abdalla M, Agarwal R, Ahmad F, Anaya G, Attia Z, Bull S, Chang A, Commodore-Mensah Y, Ferdinand K, Kawamoto K, Khera R, Leopold J, Luo J, Makhni S, Mortazavi B, Oh Y, Savage L, Spatz E, Stergiou G, Turakhia M, Whelton P, Yancy C, Iturriaga E. Transforming Hypertension Diagnosis and Management in The Era of Artificial Intelligence: A 2023 National Heart, Lung, and Blood Institute (NHLBI) Workshop Report. Hypertension 2024 PMID: 39011653, DOI: 10.1161/hypertensionaha.124.22095.Peer-Reviewed Original ResearchMachine learning toolsManagement of hypertensionNational HeartArtificial intelligenceBlood InstitutePredictive of incident hypertensionHealth care systemImplementation challengesDiverse group of stakeholdersAI toolsPopulation healthMeasurement of blood pressureCare systemHealth careIncident hypertensionHypertension riskEra of artificial intelligenceHypertension diagnosisLearning toolsManaging hypertensionHypertension-related complicationsAntihypertensive medicationsHealthPublic healthGroups of stakeholdersEvaluating Ischemic Heart Disease in Women: Focus on Angina With Nonobstructive Coronary Arteries (ANOCA)
Maayah M, Latif N, Vijay A, Gallegos C, Cigarroa N, Martinez E, Mazure C, Miller E, Spatz E, Shah S. Evaluating Ischemic Heart Disease in Women: Focus on Angina With Nonobstructive Coronary Arteries (ANOCA). Journal Of The Society For Cardiovascular Angiography & Interventions 2024, 3: 102195. PMID: 39166160, PMCID: PMC11330936, DOI: 10.1016/j.jscai.2024.102195.Peer-Reviewed Original ResearchIschemic heart diseaseNonobstructive coronary arteriesCoronary artery diseaseArtery diseaseObstructive coronary artery diseaseCoronary arteryLong-term cardiovascular prognosisHeart diseaseSuspected ischemic heart diseaseAtherosclerotic coronary artery diseaseCoronary vasomotor disordersPretest probability of diseasePragmatic diagnostic algorithmExpert consensus documentEvaluating ischemic heart diseaseImpact quality of lifeQuality of lifeSymptomatic patientsPretest probabilityANOCACardiovascular prognosisVasomotor disordersDiagnostic evaluationPersistent symptomsDiagnostic strategiesDevelopment and multinational validation of an algorithmic strategy for high Lp(a) screening
Aminorroaya A, Dhingra L, Oikonomou E, Saadatagah S, Thangaraj P, Vasisht Shankar S, Spatz E, Khera R. Development and multinational validation of an algorithmic strategy for high Lp(a) screening. Nature Cardiovascular Research 2024, 3: 558-566. PMID: 39195936, DOI: 10.1038/s44161-024-00469-1.Peer-Reviewed Original ResearchElectronic health recordsAssociated with premature atherosclerotic cardiovascular diseaseElevated Lp(aHealth recordsUK BiobankPremature atherosclerotic cardiovascular diseaseMachine learning modelsAtherosclerotic cardiovascular diseaseCohort studyReal-world settingsTargeted screeningCardiovascular diseaseLearning modelsNovel targeted therapeuticsAlgorithmic strategiesCohortProbability thresholdScreeningClinical featuresValidation cohortElevated lipoproteinRisk inspectionARICLp(aGlobal considerations for informed consent with shared decision-making in the digital age
St John E, Moore C, Pillarisetti R, Spatz E. Global considerations for informed consent with shared decision-making in the digital age. BMJ Evidence-Based Medicine 2024, bmjebm-2023-112740. PMID: 38697783, DOI: 10.1136/bmjebm-2023-112740.Peer-Reviewed Original ResearchDigital Health Interventions for Hypertension Management in US Populations Experiencing Health Disparities
Katz M, Mszar R, Grimshaw A, Gunderson C, Onuma O, Lu Y, Spatz E. Digital Health Interventions for Hypertension Management in US Populations Experiencing Health Disparities. JAMA Network Open 2024, 7: e2356070. PMID: 38353950, PMCID: PMC10867699, DOI: 10.1001/jamanetworkopen.2023.56070.Peer-Reviewed Original ResearchConceptsDigital health interventionsHealth disparitiesHealth interventionsSystematic reviewSystolic BPSocial determinants of healthHypertension managementCommunity health workersFactors associated with cardiovascular diseaseDeterminants of healthLeveraging digital healthRemote BP monitoringDigital health technologiesStandard care groupMeta-analysisBlood pressureDiastolic BPPreferred Reporting ItemsControl groupSystolic BP changeBaseline to 6Random-effects modelSkilled nursingCultural tailoringSocial determinantsPrioritizing the Exposome to Reduce Cardiovascular Disease Burden
Spatz E, Chen K, Krumholz H. Prioritizing the Exposome to Reduce Cardiovascular Disease Burden. JAMA Cardiology 2024, 9: 163-164. PMID: 37955872, DOI: 10.1001/jamacardio.2023.4722.Peer-Reviewed Original ResearchAssociation of marital/partner status with hospital readmission among young adults with acute myocardial infarction.
Zhu C, Dreyer R, Li F, Spatz E, Caraballo C, Mahajan S, Raparelli V, Leifheit E, Lu Y, Krumholz H, Spertus J, D'Onofrio G, Pilote L, Lichtman J. Association of marital/partner status with hospital readmission among young adults with acute myocardial infarction. PLOS ONE 2024, 19: e0287949. PMID: 38277368, PMCID: PMC10817183, DOI: 10.1371/journal.pone.0287949.Peer-Reviewed Original ResearchConceptsMarital/partner statusPsychosocial factorsAcute myocardial infarctionYoung adultsHospital dischargeYear of hospital dischargeYoung acute myocardial infarctionAssociated with 1.3-foldCohort of young adultsLong-term readmissionCox proportional hazards modelsStatus interactionSimilar-aged menMyocardial infarctionProportional hazards modelUnpartnered statusPatient interviewsPhysician panelCardiovascular healthHospital readmissionSocioeconomic factorsAMI survivorsSequential adjustmentCardiac readmissionMultiple imputationPsychological Health and Ischemic Heart Disease in Women: A Review of Current Evidence and Clinical Considerations across the Healthspan
Gaffey A, Spatz E. Psychological Health and Ischemic Heart Disease in Women: A Review of Current Evidence and Clinical Considerations across the Healthspan. Current Atherosclerosis Reports 2024, 26: 45-58. PMID: 38240928, PMCID: PMC11219074, DOI: 10.1007/s11883-023-01185-0.Peer-Reviewed Original ResearchConceptsIschemic heart disease riskPsychological healthIschemic heart diseasePsychosocial stressRisk of ischemic heart diseaseIschemic heart disease diagnosisPsychological factorsStudy of psychological factorsPositive psychological factorsOptimal psychological healthHeart diseaseSignificant life eventsIHD riskPsychosocial factorsSense of purposeWoman's riskPsychological screeningPsychological assessmentPsychological interventionsLife eventsSex-specific factorsSocial isolationHealthVulnerable groupsNarrative review
Clinical Care
Overview
Erica Spatz, MD, MHS, is a general cardiologist who treats a variety of conditions that relate to the heart and circulatory system. In addition to emphasizing prevention to her patients, she is an active researcher who investigates ways to prevent heart attacks and strokes, so that more people can live long and healthy lives.
“The field of prevention is exciting. We are rapidly developing new ways of estimating people’s risk of future heart disease, and we have new medications and tools to reduce that risk,” says Dr. Spatz, who is especially interested in applying “precision medicine” to prevention. This is making conversations with patients in her practice more specific and less generic. “I am thinking, ‘What are the patient’s risk factors? What's unique about their biology, their genetics, and their biography? What are the aspects of their lives that may be contributing to cardiovascular risk or, on the contrary, promoting cardiovascular health? What might be the best strategies for reducing risk and improving their health outcomes?’ The onus is on us as clinicians, physicians, nurses, and pharmacists, to really understand the person before us.”
We need to be working at multiple levels to reduce heart disease, Spatz says. “We need strong policies and coordinated community efforts to promote healthier lifestyles and overall well-being. There is so much we can be doing to make ‘healthy’ the easy choice for our population. At the individual level, there is an opportunity to better capture the personalized biological factors, experiences, and behaviors that inform cardiovascular risk—through digital technology and surveys.”
Lifestyle changes are often considered the bedrock of preventing heart disease, and while this can be difficult for some people—especially if they are overwhelmed with other life challenges—small achievable goals go a long way, Dr. Spatz says. “I try to think about this from a lifelong perspective. Cardiovascular disease prevention is hard work and people can't be perfect all the time, so I try to find specific things people can work on as well as opportunities when this makes sense in a person's life. If I can help them to define a healthier path, then I think the ripple effects can be massive.”
In addition to caring for patients, Dr. Spatz serves as a clinical investigator for the Center for Outcomes Research & Evaluation (CORE), an organization at Yale School of Medicine that focuses on health care quality, where she researches individualized approaches to preventing and managing cardiovascular disease, health disparities across the health care system, and ways to engage patients as partners in their care. She also is a cofounder of Project Access-New Haven—a network of physicians, hospitals, and community organizations partnering to provide donated specialty care to underserved patients in New Haven.
Clinical Specialties
Fact Sheets
Heart Attack (Myocardial Infarction)
Learn More on Yale MedicineHeart Disease in Women
Learn More on Yale MedicineChest Pain
Learn More on Yale MedicineCoronary Artery Disease (CAD)
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Yale Medicine News
News & Links
News
- July 24, 2024
Yale Department of Internal Medicine Faculty Promotions and Appointments (July 2024)
- June 27, 2024
What to Know about Lipoprotein(a)
- May 22, 2024Source: The Washington Post
Just how dangerous is turbulence?
- April 01, 2024
Yale Faculty Present Groundbreaking Clinical Research at the 2024 American College of Cardiology Scientific Sessions