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Mridu Gulati, MD

Associate Professor of Medicine (Pulmonary, Critical Care and Sleep Medicine)

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Mridu Gulati, MD

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Lippard Laboratory of Clinical Investigation (LLCI)
15 York Street, Ste 101D
New Haven, CT 06510

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Pulmonary, Critical Care & Sleep Medicine
PO Box 208057, 300 Cedar Street
New Haven, CT 06520-8057
United States

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Selected Publications

Circulating Mitochondrial DNA is associated with High Levels of Fatigue in Two Independent Sarcoidosis CohortsFiorini V, Hu B, Sun Y, Yu S, McGovern J, Gandhi S, Woo S, Turcotte-Foster S, Pivarnik T, Khan Z, Adams T, Herzog E, Kaminski N, Gulati M, Ryu C. Circulating Mitochondrial DNA is associated with High Levels of Fatigue in Two Independent Sarcoidosis Cohorts. CHEST Journal 2023 PMID: 37977267, DOI: 10.1016/j.chest.2023.11.020.
EVALUATION OF CONTENT VALIDITY OF A NEW EXPOSURE ASSESSMENT QUESTIONNAIRE IN PATIENTS WITH FIBROSING INTERSTITIAL LUNG DISEASESSWAMINATHAN A, MCFATRICH M, MKUMBA L, WRIGHT L, REDLICH C, SNYDER L, REEVE B, OLSON A, GULATI M. EVALUATION OF CONTENT VALIDITY OF A NEW EXPOSURE ASSESSMENT QUESTIONNAIRE IN PATIENTS WITH FIBROSING INTERSTITIAL LUNG DISEASES. CHEST Journal 2023, 164: a5103-a5104. DOI: 10.1016/j.chest.2023.07.3304.
Proteomic profiling demonstrates inflammatory and endotheliopathy signatures associated with impaired cardiopulmonary exercise hemodynamic profile in Post Acute Sequelae of SARS‐CoV‐2 infection (PASC) syndromeSingh I, Leitner B, Wang Y, Zhang H, Joseph P, Lutchmansingh D, Gulati M, Possick J, Damsky W, Hwa J, Heerdt P, Chun H. Proteomic profiling demonstrates inflammatory and endotheliopathy signatures associated with impaired cardiopulmonary exercise hemodynamic profile in Post Acute Sequelae of SARS‐CoV‐2 infection (PASC) syndrome. Pulmonary Circulation 2023, 13: e12220. PMID: 37091121, PMCID: PMC10113513, DOI: 10.1002/pul2.12220.
Autoimmune comorbidities associated with sarcoidosis: a case-control study in the All of Us research programMurphy M, Edemobi P, Leasure A, Gulati M, Miller E, Damsky W, Cohen J. Autoimmune comorbidities associated with sarcoidosis: a case-control study in the All of Us research program. Rheumatology Advances In Practice 2023, 7: rkad030. DOI: 10.1093/rap/rkad030.
“Long Haulers”Lutchmansingh D, Sevilla J, Possick J, Gulati M. “Long Haulers”. Seminars In Respiratory And Critical Care Medicine 2023, 44: 130-142. PMID: 36646091, DOI: 10.1055/s-0042-1759568.
Rationale and design of the SARCoidosis Outcomes in all respiratory Viral Infectious Diseases (SARCOVID) StudyStrykowski R, Patel DC, Neto MR, Hena KM, Gulati M, Maier LA, Patterson K. Rationale and design of the SARCoidosis Outcomes in all respiratory Viral Infectious Diseases (SARCOVID) Study. BMJ Open Respiratory Research 2022, 9: e001254. PMID: 35882424, PMCID: PMC9329732, DOI: 10.1136/bmjresp-2022-001254.
Occupational and environmental exposures in the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis (GRADS) studyRyan SM, Mroz MM, Herzog EL, Ryu C, Fingerlin TE, Maier LA, Gulati M. Occupational and environmental exposures in the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis (GRADS) study. Respiratory Medicine 2022, 200: 106923. PMID: 35932543, DOI: 10.1016/j.rmed.2022.106923.
Inhibition of type 1 immunity with tofacitinib is associated with marked improvement in longstanding sarcoidosisDamsky W, Wang A, Kim DJ, Young BD, Singh K, Murphy MJ, Daccache J, Clark A, Ayasun R, Ryu C, McGeary MK, Odell ID, Fazzone-Chettiar R, Pucar D, Homer R, Gulati M, Miller EJ, Bosenberg M, Flavell RA, King B. Inhibition of type 1 immunity with tofacitinib is associated with marked improvement in longstanding sarcoidosis. Nature Communications 2022, 13: 3140. PMID: 35668129, PMCID: PMC9170782, DOI: 10.1038/s41467-022-30615-x.
Disparities in Lung Transplant among Patients with Idiopathic Pulmonary Fibrosis: An Analysis of the IPF-PRO RegistrySwaminathan A, Hellkamp A, Neely M, Bender S, Paoletti L, White E, Palmer S, Whelan T, Dilling D, Baker A, Beegle S, Belperio J, Condos R, Cordova F, Culver D, Fitzgerald J, Flaherty K, Gibson K, Gulati M, Guntupalli K, Gupta N, Case A, Hotchkin D, Huie T, Kaner R, Kim H, Lancaster L, Lasky J, Lee D, Liesching T, Lipchik R, Lobo J, Luckhardt T, Mageto Y, Menon P, Morrison L, Namen A, Oldham J, Paul T, Zhang D, Porteous M, Raj R, Ramaswamy M, Russell T, Sachs P, Safdar Z, Shafazand S, Siddiqi A, Sigal B, Strek M, Suliman S, Tabak J, Walia R. Disparities in Lung Transplant among Patients with Idiopathic Pulmonary Fibrosis: An Analysis of the IPF-PRO Registry. Annals Of The American Thoracic Society 2022, 19: 981-990. PMID: 35073248, PMCID: PMC9169123, DOI: 10.1513/annalsats.202105-589oc.
Impaired Stressed Blood Volume Augmentation in Post-COVID-19 PatientsSavarimuthu S, Joseph P, Lutchmansingh D, Possick J, Gulati M, Cullinan M, Kreiger J, Heerdt P, Singh I. Impaired Stressed Blood Volume Augmentation in Post-COVID-19 Patients. 2022, a5418-a5418. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5418.
Cough-Specific Quality of Life Predicts Disease Progression Among Patients With Interstitial Lung Disease Data From the Pulmonary Fibrosis Foundation Patient RegistryLee J, White E, Freiheit E, Scholand M, Strek M, Podolanczuk A, Patel N, Foundation P, Bascom R, Belloli E, Bhatt N, Bhorade S, Case A, Castriotta R, Criner G, Danoff S, De Andrade J, Desai A, Glassberg M, Glazer C, Gulati M, Gupta N, Hamblin M, Huie T, Kaner R, Kass D, Kim H, Kreider M, Lancaster L, Lasky J, Limper A, Montesi S, Mooney J, Morrison L, Nambiar A, Nathan S, Natt B, Paul T, Perez R, Podolanczuk A, Raghu G, Scholand M, Shifren A, Strek M, Todd N, Walia R, Weight S, Whelan T, Wolters P. Cough-Specific Quality of Life Predicts Disease Progression Among Patients With Interstitial Lung Disease Data From the Pulmonary Fibrosis Foundation Patient Registry. CHEST Journal 2022, 162: 603-613. PMID: 35337809, PMCID: PMC9808640, DOI: 10.1016/j.chest.2022.03.025.
Occupational Exposome and Lung HealthMacMurdo M, Culver D, Gulati M. Occupational Exposome and Lung Health. 2022, 51-91. DOI: 10.1007/978-3-030-90185-1_4.
Correction to: Association of Circulating Proteins with Death or Lung Transplant in Patients with Idiopathic Pulmonary Fibrosis in the IPF-PRO Registry CohortTodd JL, Neely ML, Overton R, Mulder H, Roman J, Lasky JA, de Andrade JA, Gulati M, Huang H, Leonard TB, Hesslinger C, Noth I, Belperio JA, Flaherty KR, Palmer SM. Correction to: Association of Circulating Proteins with Death or Lung Transplant in Patients with Idiopathic Pulmonary Fibrosis in the IPF-PRO Registry Cohort. Lung 2022, 200: 19-19. PMID: 35166906, PMCID: PMC8881254, DOI: 10.1007/s00408-022-00516-3.
Association of Circulating Proteins with Death or Lung Transplant in Patients with Idiopathic Pulmonary Fibrosis in the IPF-PRO Registry CohortTodd JL, Neely ML, Overton R, Mulder H, Roman J, Lasky JA, de Andrade JA, Gulati M, Huang H, Leonard TB, Hesslinger C, Noth I, Belperio JA, Flaherty KR, Palmer SM. Association of Circulating Proteins with Death or Lung Transplant in Patients with Idiopathic Pulmonary Fibrosis in the IPF-PRO Registry Cohort. Lung 2022, 200: 11-18. PMID: 35066606, PMCID: PMC8881240, DOI: 10.1007/s00408-021-00505-y.
Occupational Interstitial Lung DiseaseGulati M, Maier L. Occupational Interstitial Lung Disease. 2022, 368-380. DOI: 10.1016/b978-0-12-801238-3.11503-x.
Abstract 6991: Impaired Systemic Oxygen Extraction Relates to Reduced Exercise Capacity in Post-COVID-19 Long Hauler SyndromeBiondi M, Joseph P, Gulati M, Possick J, Lutchmansingh D, Cullinan M, Heerdt P, Singh I. Abstract 6991: Impaired Systemic Oxygen Extraction Relates to Reduced Exercise Capacity in Post-COVID-19 Long Hauler Syndrome. Circulation 2021, 144: a6991-a6991. DOI: 10.1161/circ.144.suppl_1.6991.
UNEXPLAINED DYSPNEA IN A PATIENT WITH A HISTORY OF COVID-19Biondi M, Gulati M, Possick J, Joseph P, Singh I, Lutchmansingh D. UNEXPLAINED DYSPNEA IN A PATIENT WITH A HISTORY OF COVID-19. CHEST Journal 2021, 160: a2373-a2374. PMCID: PMC8503500, DOI: 10.1016/j.chest.2021.07.2054.
Transcriptomics of bronchoalveolar lavage cells identifies new molecular endotypes of sarcoidosisVukmirovic M, Yan X, Gibson KF, Gulati M, Schupp JC, DeIuliis G, Adams TS, Hu B, Mihaljinec A, Woolard TN, Lynn H, Emeagwali N, Herzog EL, Chen ES, Morris A, Leader JK, Zhang Y, Garcia JGN, Maier LA, Collman RG, Drake WP, Becich MJ, Hochheiser H, Wisniewski SR, Benos PV, Moller DR, Prasse A, Koth LL, Kaminski N. Transcriptomics of bronchoalveolar lavage cells identifies new molecular endotypes of sarcoidosis. European Respiratory Journal 2021, 58: 2002950. PMID: 34083402, PMCID: PMC9759791, DOI: 10.1183/13993003.02950-2020.
Regulation of Immune Cell Matrix Metalloproteinase Production by the Sarcoidosis Lung MatrisomeLiu A, Sun H, Winkler J, Reeves B, Gulati M, Wang W, Lam T, Herzog E. Regulation of Immune Cell Matrix Metalloproteinase Production by the Sarcoidosis Lung Matrisome. 2021, a4262-a4262. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a4262.
IL-15 Is Independent of Pulmonary Sarcoid Granuloma Formation In VivoMinasyan M, Sharma L, Pivarnik T, Liu W, Adams T, Bermejo S, Peng X, Ishikawa G, Perry C, Kaminski N, Gulati M, Herzog E, Dela Cruz C, Ryu C. IL-15 Is Independent of Pulmonary Sarcoid Granuloma Formation In Vivo. 2021, a4263-a4263. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a4263.
Biophysical and Biochemical Contributions to Leukocyte Phenotypes in Scleroderma Associated Interstitial Lung DiseaseSun H, Winkler J, Laranger R, Liu A, Perry C, Gulati M, Homer R, Mak M, Gonzalez A, Herzog E. Biophysical and Biochemical Contributions to Leukocyte Phenotypes in Scleroderma Associated Interstitial Lung Disease. 2021, a4653-a4653. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a4653.
Elevated IL-15 concentrations in the sarcoidosis lung are independent of granuloma burden and disease phenotypesMinasyan M, Sharma L, Pivarnik T, Liu W, Adams T, Bermejo S, Peng X, Liu A, Ishikawa G, Perry C, Kaminski N, Gulati M, Herzog EL, Dela Cruz CS, Ryu C. Elevated IL-15 concentrations in the sarcoidosis lung are independent of granuloma burden and disease phenotypes. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2021, 320: l1137-l1146. PMID: 33851886, PMCID: PMC8285626, DOI: 10.1152/ajplung.00575.2020.
Macrophage-derived netrin-1 drives adrenergic nerve–associated lung fibrosisGao R, Peng X, Perry C, Sun H, Ntokou A, Ryu C, Gomez JL, Reeves BC, Walia A, Kaminski N, Neumark N, Ishikawa G, Black KE, Hariri LP, Moore MW, Gulati M, Homer RJ, Greif DM, Eltzschig HK, Herzog EL. Macrophage-derived netrin-1 drives adrenergic nerve–associated lung fibrosis. Journal Of Clinical Investigation 2021, 131: e136542. PMID: 33393489, PMCID: PMC7773383, DOI: 10.1172/jci136542.
Delphi Consensus Recommendations on Management of Dosing, Adverse Events, and Comorbidities in the Treatment of Idiopathic Pulmonary Fibrosis with NintedanibRahaghi F, Belperio JA, Fitzgerald J, Gulati M, Hallowell R, Highland KB, Huie TJ, Kim HJ, Kolb M, Lasky JA, Southern BD, Swigris JJ, de Andrade JA. Delphi Consensus Recommendations on Management of Dosing, Adverse Events, and Comorbidities in the Treatment of Idiopathic Pulmonary Fibrosis with Nintedanib. Clinical Medicine Insights Circulatory Respiratory And Pulmonary Medicine 2021, 15: 11795484211006050. PMID: 33854398, PMCID: PMC8013629, DOI: 10.1177/11795484211006050.
The Pulmonary Fibrosis Foundation Patient Registry. Rationale, Design, and Methods.Wang BR, Edwards R, Freiheit EA, Ma Y, Burg C, de Andrade J, Lancaster L, Lindell K, Nathan SD, Raghu G, Gibson K, Gulati M, Mason W, Noth I, Schmidt B, Spino C, Staszak S, Stauffer J, Wolters PJ, Cosgrove GP, Flaherty KR. The Pulmonary Fibrosis Foundation Patient Registry. Rationale, Design, and Methods. Annals Of The American Thoracic Society 2020, 17: 1620-1628. PMID: 32776789, DOI: 10.1513/annalsats.202001-035sd.
A Clinic Blueprint for Post-Coronavirus Disease 2019 RECOVERY Learning From the Past, Looking to the FutureLutchmansingh DD, Knauert MP, Antin-Ozerkis DE, Chupp G, Cohn L, Dela Cruz CS, Ferrante LE, Herzog EL, Koff J, Rochester CL, Ryu C, Singh I, Tickoo M, Winks V, Gulati M, Possick JD. A Clinic Blueprint for Post-Coronavirus Disease 2019 RECOVERY Learning From the Past, Looking to the Future. CHEST Journal 2020, 159: 949-958. PMID: 33159907, PMCID: PMC7641526, DOI: 10.1016/j.chest.2020.10.067.
Antifibrotic Drug Use in Patients with Idiopathic Pulmonary Fibrosis. Data from the IPF-PRO RegistrySalisbury M, Conoscenti C, Culver D, Yow E, Neely M, Bender S, Hartmann N, Palmer S, Leonard T, Baker A, Beegle S, Belperio J, Condos R, Cordova F, Culver D, Dilling D, Fitzgerald J, Flaherty K, Gibson K, Gulati M, Guntupalli K, Gupta N, Case A, Hotchkin D, Huie T, Kaner R, Kim H, Lancaster L, Lasky J, Lee D, Liesching T, Lipchik R, Lobo J, Luckhardt (formerly Joao de Andrade) T, Mageto Y, Malik N, Menon P, Morrison L, Namen A, Oldham J, Paul T, Podolanczuk A, Porteous M, Raj R, Ramaswamy M, Russell T, Sachs P, Safdar Z, Shafazand S, Siddiqi A, Sigal B, Strek M, Suliman S, Tabak J, Walia R, Whelan T. Antifibrotic Drug Use in Patients with Idiopathic Pulmonary Fibrosis. Data from the IPF-PRO Registry. Annals Of The American Thoracic Society 2020, 17: 1413-1423. PMID: 32574517, PMCID: PMC7640723, DOI: 10.1513/annalsats.201912-880oc.
Essential Components of an Interstitial Lung Disease Clinic Results From a Delphi Survey and Patient Focus Group AnalysisGraney B, He C, Marll M, Matson S, Bianchi P, Cosgrove G, Lee J, Collaborators P, Abrencillo R, Bascom R, Scholand M, Bhatt N, Case A, Chaudhary S, Culver D, Danoff S, Desai A, Dilling D, Glazer C, Gulati M, Gupta N, Hamblin M, Hamzeh N, Huie T, Kim H, King C, Kreider M, Lacamera P, Lancaster L, Luckhardt T, Mageto Y, Kottman R, McCormick J, Mehrad B, Menon P, Montesi S, Mooney J, Moore D, Moua T, Nambiar A, Oldham J, Patel D, Paul T, Perez R, Podolanczuk A, Ramaswamy M, Roe D, Saad M, Sandbo N, Schaumberg T, Schmidt S, Shea B, Shifren A, Strek M, Thavarajah K, Todd N, Veeraraghavan S, Weight S, Wolters P, Zibrak J. Essential Components of an Interstitial Lung Disease Clinic Results From a Delphi Survey and Patient Focus Group Analysis. CHEST Journal 2020, 159: 1517-1530. PMID: 33031832, PMCID: PMC7534733, DOI: 10.1016/j.chest.2020.09.256.
FORGING RELATIONSHIPS THROUGH COMMUNICATION AND COLLABORATION BETWEEN ILD CENTERS AND COMMUNITY PULMONOLOGISTS IMPROVES PATIENT CAREVajdos J, Swigris J, Glassberg M, Gulati M, Olson A, Padilla M, Shifren A, Bruno T, Miller S, Harty T. FORGING RELATIONSHIPS THROUGH COMMUNICATION AND COLLABORATION BETWEEN ILD CENTERS AND COMMUNITY PULMONOLOGISTS IMPROVES PATIENT CARE. CHEST Journal 2020, 158: a1330-a1332. DOI: 10.1016/j.chest.2020.08.1210.
Association of neoepitopes with disease severity and respiratory hospitalization in patients with IPFOldham J, Todd J, Neely M, Mulder H, Overton R, Kim H, Gulati M, Leonard T, Palmer S, Noth I, Hesslinger C. Association of neoepitopes with disease severity and respiratory hospitalization in patients with IPF. 2020, 5188. DOI: 10.1183/13993003.congress-2020.5188.
Diagnosis of Hypersensitivity Pneumonitis in Adults. An Official ATS/JRS/ALAT Clinical Practice GuidelineRaghu G, Remy-Jardin M, Ryerson CJ, Myers JL, Kreuter M, Vasakova M, Bargagli E, Chung JH, Collins BF, Bendstrup E, Chami HA, Chua AT, Corte TJ, Dalphin JC, Danoff SK, Diaz-Mendoza J, Duggal A, Egashira R, Ewing T, Gulati M, Inoue Y, Jenkins AR, Johannson KA, Johkoh T, Tamae-Kakazu M, Kitaichi M, Knight SL, Koschel D, Lederer DJ, Mageto Y, Maier LA, Matiz C, Morell F, Nicholson AG, Patolia S, Pereira CA, Renzoni EA, Salisbury ML, Selman M, Walsh SLF, Wuyts WA, Wilson KC. Diagnosis of Hypersensitivity Pneumonitis in Adults. An Official ATS/JRS/ALAT Clinical Practice Guideline. American Journal Of Respiratory And Critical Care Medicine 2020, 202: e36-e69. PMID: 32706311, PMCID: PMC7397797, DOI: 10.1164/rccm.202005-2032st.
Associations between Patient-reported Outcomes and Death or Lung transplant in IPF: Data from the IPF-PRO RegistryCase AH, Hellkamp AS, Neely ML, Bender S, Dilling DF, Gulati M, Hotchkin DL, Huie TJ, Lancaster L, Snyder LD, Conoscenti CS, Palmer S. Associations between Patient-reported Outcomes and Death or Lung transplant in IPF: Data from the IPF-PRO Registry. Annals Of The American Thoracic Society 2020, 0: 699-705. PMID: 32040340, PMCID: PMC7258421, DOI: 10.1513/annalsats.201906-437oc.
Adrenergic Nerve-Associated Lung Fibrosis Is Driven by Myeloid Netrin-1Perry C, Gao R, Peng X, Ntokou A, Ryu C, Gomez J, Reeves B, Walia A, Sun H, Black K, Hariri L, Moore M, Gulati M, Homer R, Greif D, Eltzschig H, Herzog E. Adrenergic Nerve-Associated Lung Fibrosis Is Driven by Myeloid Netrin-1. 2020, a2410-a2410. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2410.
Sarcoidosis Extracellular Matrix Regulation of Immune Cell PhenotypeLiu A, Sun H, Ledesma-Mendoza A, Winkler J, Reeves B, Gulati M, Wang W, Lam T, Herzog E. Sarcoidosis Extracellular Matrix Regulation of Immune Cell Phenotype. 2020, a5530-a5530. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a5530.
Rationale, Design, and Results of the Idiopathic Pulmonary Fibrosis "Sadokine" Pilot StudyKhan Z, Carrano D, Minasyan M, Gulati M, Ryu C, Herzog E. Rationale, Design, and Results of the Idiopathic Pulmonary Fibrosis "Sadokine" Pilot Study. 2020, a6580-a6580. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6580.
Association of Circulating Proteins with Death or Lung Transplant in the IPF-PRO Registry CohortTodd J, Neely M, Overton R, Mulder H, Roman J, Lasky J, De Andrade J, Gulati M, Huang H, Leonard T, Hesslinger C, Noth I, Belperio J, Flaherty K, Palmer S. Association of Circulating Proteins with Death or Lung Transplant in the IPF-PRO Registry Cohort. 2020, a6205-a6205. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6205.
Disease Severity and Quality of Life in Patients With Idiopathic Pulmonary Fibrosis A Cross-Sectional Analysis of the IPF-PRO RegistryO’Brien E, Hellkamp A, Neely M, Swaminathan A, Bender S, Snyder L, Culver D, Conoscenti C, Todd J, Palmer S, Leonard T, investigators I, Asi W, Baker A, Beegle S, Belperio J, Condos R, Cordova F, Culver D, de Andrade J, Dilling D, Flaherty K, Glassberg M, Gulati M, Guntupalli K, Gupta N, Case A, Hotchkin D, Huie T, Kaner R, Kim H, Kreider M, Lancaster L, Lasky J, Lederer D, Lee D, Liesching T, Lipchik R, Lobo J, Mageto Y, Menon P, Morrison L, Namen A, Oldham J, Raj R, Ramaswamy M, Russell T, Sachs P, Safdar Z, Sigal B, Silhan L, Strek M, Suliman S, Tabak J, Walia R, Whelan T. Disease Severity and Quality of Life in Patients With Idiopathic Pulmonary Fibrosis A Cross-Sectional Analysis of the IPF-PRO Registry. CHEST Journal 2020, 157: 1188-1198. PMID: 31954102, DOI: 10.1016/j.chest.2019.11.042.
Peripheral blood proteomic profiling of idiopathic pulmonary fibrosis biomarkers in the multicentre IPF-PRO RegistryTodd JL, Neely ML, Overton R, Durham K, Gulati M, Huang H, Roman J, Newby LK, Flaherty KR, Vinisko R, Liu Y, Roy J, Schmid R, Strobel B, Hesslinger C, Leonard TB, Noth I, Belperio JA, Palmer SM. Peripheral blood proteomic profiling of idiopathic pulmonary fibrosis biomarkers in the multicentre IPF-PRO Registry. Respiratory Research 2019, 20: 227. PMID: 31640794, PMCID: PMC6805665, DOI: 10.1186/s12931-019-1190-z.
Patient Registries in Idiopathic Pulmonary FibrosisCulver DA, Behr J, Belperio JA, Corte TJ, de Andrade JA, Flaherty KR, Gulati M, Huie TJ, Lancaster LH, Roman J, Ryerson CJ, Kim HJ. Patient Registries in Idiopathic Pulmonary Fibrosis. American Journal Of Respiratory And Critical Care Medicine 2019, 200: 160-167. PMID: 31034241, PMCID: PMC6635784, DOI: 10.1164/rccm.201902-0431ci.
Plasma mitochondrial DNA is associated with extrapulmonary sarcoidosisRyu C, Brandsdorfer C, Adams T, Hu B, Kelleher DW, Yaggi M, Manning EP, Walia A, Reeves B, Pan H, Winkler J, Minasyan M, Dela Cruz CS, Kaminski N, Gulati M, Herzog EL. Plasma mitochondrial DNA is associated with extrapulmonary sarcoidosis. European Respiratory Journal 2019, 54: 1801762. PMID: 31273041, PMCID: PMC8088542, DOI: 10.1183/13993003.01762-2018.
Predictors of death or lung transplant after a diagnosis of idiopathic pulmonary fibrosis: insights from the IPF-PRO RegistrySnyder L, Neely ML, Hellkamp AS, O’Brien E, de Andrade J, Conoscenti CS, Leonard T, Bender S, Gulati M, Culver DA, Kaner RJ, Palmer S, Kim HJ. Predictors of death or lung transplant after a diagnosis of idiopathic pulmonary fibrosis: insights from the IPF-PRO Registry. Respiratory Research 2019, 20: 105. PMID: 31142314, PMCID: PMC6542049, DOI: 10.1186/s12931-019-1043-9.
Circulating Mitochondrial DNA Is Associated with Fibroblast Activation and Disease Progression in Scleroderma Associated Interstitial Lung DiseaseRyu C, Sun H, Winkler J, Meena S, Walia A, Minasyan M, Brandsdorfer C, Gulati M, Peng X, Herzog E. Circulating Mitochondrial DNA Is Associated with Fibroblast Activation and Disease Progression in Scleroderma Associated Interstitial Lung Disease. 2019, a7219-a7219. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7219.
Peripheral Blood Proteomic Profiling to Distinguish Disease Biomarkers in the Multicenter IPF-PRO Registry CohortTodd J, Durham K, Overton R, Neely M, Belperio J, Gulati M, Huang H, Roman J, Newby L, Noth I, Vinisko R, Liu Y, Hesslinger C, Leonard T, Flaherty K, Palmer S, on behalf of the IPF-PRO Registry i. Peripheral Blood Proteomic Profiling to Distinguish Disease Biomarkers in the Multicenter IPF-PRO Registry Cohort. 2019, a4325-a4325. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4325.
Association of Circulating Proteins with Disease Specific Measures in the Multicenter IPF-PRO Registry CohortTodd J, Neely M, Overton R, Gulati M, Huang H, Roman J, Flaherty K, Vinisko R, Hesslinger C, Leonard T, Noth I, Palmer S, Belperio J, on behalf of the IPF-PRO Registry i. Association of Circulating Proteins with Disease Specific Measures in the Multicenter IPF-PRO Registry Cohort. 2019, a5838-a5838. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5838.
Predictors of death or transplant in patients with idiopathic pulmonary fibrosis in the IPF-PRO RegistrySnyder L, Neely M, Hellkamp A, O'Brien E, Flaherty K, De Andrade J, Conoscenti C, Leonard T, Bender S, Gulati M, Culver D, Kaner R, Palmer S, Kim H. Predictors of death or transplant in patients with idiopathic pulmonary fibrosis in the IPF-PRO Registry. 2018, pa2196. DOI: 10.1183/13993003.congress-2018.pa2196.
Insights from RNA-sequencing of bronchoalveolar lavage cells in a large sarcoidosis cohortVukmirovic M, Yan X, Gibson K, Gulati M, DeIuliis G, Woolard T, Adams T, Hu B, Zang W, Mihaljinec A, Luijk H, Aurelien N, O'Neal S, Becich M, Hochheiser H, Herzog E, Senior R, Chen E, Morris A, Leader J, Zhang Y, “Skip” Garcia J, Wisniewski S, Benos P, Maier L, Moller D, Drake W, Koth L, Kaminski N. Insights from RNA-sequencing of bronchoalveolar lavage cells in a large sarcoidosis cohort. 2017, oa2907. DOI: 10.1183/1393003.congress-2017.oa2907.
Antifibrotic role of vascular endothelial growth factor in pulmonary fibrosisMurray LA, Habiel DM, Hohmann M, Camelo A, Shang H, Zhou Y, Coelho AL, Peng X, Gulati M, Crestani B, Sleeman MA, Mustelin T, Moore MW, Ryu C, Osafo-Addo AD, Elias JA, Lee CG, Hu B, Herazo-Maya JD, Knight DA, Hogaboam CM, Herzog EL. Antifibrotic role of vascular endothelial growth factor in pulmonary fibrosis. JCI Insight 2017, 2: e92192. PMID: 28814671, PMCID: PMC5621899, DOI: 10.1172/jci.insight.92192.
Extracellular Mitochondrial DNA Is Generated by Fibroblasts and Predicts Death in Idiopathic Pulmonary FibrosisRyu C, Sun H, Gulati M, Herazo-Maya J, Chen Y, Osafo-Addo A, Brandsdorfer C, Winkler J, Blaul C, Faunce J, Pan H, Woolard T, Tzouvelekis A, Antin-Ozerkis DE, Puchalski JT, Slade M, Gonzalez AL, Bogenhagen DF, Kirillov V, Feghali-Bostwick C, Gibson K, Lindell K, Herzog RI, Dela Cruz CS, Mehal W, Kaminski N, Herzog EL, Trujillo G. Extracellular Mitochondrial DNA Is Generated by Fibroblasts and Predicts Death in Idiopathic Pulmonary Fibrosis. American Journal Of Respiratory And Critical Care Medicine 2017, 196: 1571-1581. PMID: 28783377, PMCID: PMC5754440, DOI: 10.1164/rccm.201612-2480oc.
Upper Airway Obstruction Requiring Emergent Tracheostomy Secondary to Laryngeal Sarcoidosis: A Case ReportRyu C, Herzog EL, Pan H, Homer R, Gulati M. Upper Airway Obstruction Requiring Emergent Tracheostomy Secondary to Laryngeal Sarcoidosis: A Case Report. American Journal Of Case Reports 2017, 18: 157-159. PMID: 28190872, PMCID: PMC5319306, DOI: 10.12659/ajcr.902231.
Occupational lung diseases: from old and novel exposures to effective preventive strategiesCullinan P, Muñoz X, Suojalehto H, Agius R, Jindal S, Sigsgaard T, Blomberg A, Charpin D, Annesi-Maesano I, Gulati M, Kim Y, Frank AL, Akgün M, Fishwick D, de la Hoz RE, Moitra S. Occupational lung diseases: from old and novel exposures to effective preventive strategies. The Lancet Respiratory Medicine 2017, 5: 445-455. PMID: 28089118, DOI: 10.1016/s2213-2600(16)30424-6.
Lung Diseases, OccupationalGulati M, Cullen M. Lung Diseases, Occupational. 2017, 485-490. DOI: 10.1016/b978-0-12-803678-5.00261-7.
Validation of the prognostic value of MMP‐7 in idiopathic pulmonary fibrosisTzouvelekis A, Herazo‐Maya J, Slade M, Chu J, Deiuliis G, Ryu C, Li Q, Sakamoto K, Ibarra G, Pan H, Gulati M, Antin‐Ozerkis D, Herzog EL, Kaminski N. Validation of the prognostic value of MMP‐7 in idiopathic pulmonary fibrosis. Respirology 2016, 22: 486-493. PMID: 27761978, PMCID: PMC5352520, DOI: 10.1111/resp.12920.
Plexin C1 deficiency permits synaptotagmin 7–mediated macrophage migration and enhances mammalian lung fibrosisPeng X, Moore M, Mathur A, Zhou Y, Sun H, Gan Y, Herazo‐Maya J, Kaminski N, Hu X, Pan H, Ryu C, Osafo‐Addo A, Homer RJ, Feghali‐Bostwick C, Fares W, Gulati M, Hu B, Lee C, Elias JA, Herzog EL. Plexin C1 deficiency permits synaptotagmin 7–mediated macrophage migration and enhances mammalian lung fibrosis. The FASEB Journal 2016, 30: 4056-4070. PMID: 27609773, PMCID: PMC5102121, DOI: 10.1096/fj.201600373r.
Netrin‐1 Regulates Fibrocyte Accumulation in the Decellularized Fibrotic Sclerodermatous Lung Microenvironment and in Bleomycin‐Induced Pulmonary FibrosisSun H, Zhu Y, Pan H, Chen X, Balestrini JL, Lam TT, Kanyo JE, Eichmann A, Gulati M, Fares WH, Bai H, Feghali-Bostwick CA, Gan Y, Peng X, Moore MW, White ES, Sava P, Gonzalez AL, Cheng Y, Niklason LE, Herzog EL. Netrin‐1 Regulates Fibrocyte Accumulation in the Decellularized Fibrotic Sclerodermatous Lung Microenvironment and in Bleomycin‐Induced Pulmonary Fibrosis. Arthritis & Rheumatology 2016, 68: 1251-1261. PMID: 26749424, PMCID: PMC5547894, DOI: 10.1002/art.39575.
An Update on Hypersensitivity PneumonitisGulati M. An Update on Hypersensitivity Pneumonitis. Current Respiratory Medicine Reviews 2016, 12: 33-43. DOI: 10.2174/1573398x11666151028205804.
Potential Mechanistic Links Between Aging and IPFPan H, Gulati M, Herzog E. Potential Mechanistic Links Between Aging and IPF. 2015, 409-429. DOI: 10.1142/9789814635011_0016.
Chitinase 3–like–1 and its receptors in Hermansky-Pudlak syndrome–associated lung diseaseZhou Y, He CH, Herzog EL, Peng X, Lee CM, Nguyen TH, Gulati M, Gochuico BR, Gahl WA, Slade ML, Lee CG, Elias JA. Chitinase 3–like–1 and its receptors in Hermansky-Pudlak syndrome–associated lung disease. Journal Of Clinical Investigation 2015, 125: 3178-3192. PMID: 26121745, PMCID: PMC4563747, DOI: 10.1172/jci79792.
Small Airways Disease Related to Occupational ExposuresGulati M, Teng A. Small Airways Disease Related to Occupational Exposures. Clinical Pulmonary Medicine 2015, 22: 133-140. DOI: 10.1097/cpm.0000000000000094.
Asbestosis and environmental causes of usual interstitial pneumoniaGulati M, Redlich CA. Asbestosis and environmental causes of usual interstitial pneumonia. Current Opinion In Pulmonary Medicine 2015, 21: 193-200. PMID: 25621562, PMCID: PMC4472384, DOI: 10.1097/mcp.0000000000000144.
Chitinase 3–Like 1 Suppresses Injury and Promotes Fibroproliferative Responses in Mammalian Lung FibrosisZhou Y, Peng H, Sun H, Peng X, Tang C, Gan Y, Chen X, Mathur A, Hu B, Slade MD, Montgomery RR, Shaw AC, Homer RJ, White ES, Lee CM, Moore MW, Gulati M, Lee CG, Elias JA, Herzog EL. Chitinase 3–Like 1 Suppresses Injury and Promotes Fibroproliferative Responses in Mammalian Lung Fibrosis. Science Translational Medicine 2014, 6: 240ra76. PMID: 24920662, PMCID: PMC4340473, DOI: 10.1126/scitranslmed.3007096.
Supportive Care for Patients with Pulmonary Complications of Connective Tissue DiseaseGulati M, Antin-Ozerkis D. Supportive Care for Patients with Pulmonary Complications of Connective Tissue Disease. Seminars In Respiratory And Critical Care Medicine 2014, 35: 274-282. PMID: 24668542, DOI: 10.1055/s-0034-1371538.
Pulmonary FibrosisMurray L, Homer R, Gulati M, Herzog E. Pulmonary Fibrosis. 2014, 2636-2653. DOI: 10.1016/b978-0-12-386456-7.05307-7.
Semaphorin 7a+ Regulatory T Cells Are Associated with Progressive Idiopathic Pulmonary Fibrosis and Are Implicated in Transforming Growth Factor-β1–induced Pulmonary FibrosisReilkoff RA, Peng H, Murray LA, Peng X, Russell T, Montgomery R, Feghali-Bostwick C, Shaw A, Homer RJ, Gulati M, Mathur A, Elias JA, Herzog EL. Semaphorin 7a+ Regulatory T Cells Are Associated with Progressive Idiopathic Pulmonary Fibrosis and Are Implicated in Transforming Growth Factor-β1–induced Pulmonary Fibrosis. American Journal Of Respiratory And Critical Care Medicine 2012, 187: 180-188. PMID: 23220917, PMCID: PMC3570653, DOI: 10.1164/rccm.201206-1109oc.
PrefaceRedlich CA, Blanc PD, Gulati M, Kuschner WG. Preface. Clinics In Chest Medicine 2012, 33: xi-xii. PMID: 23153617, DOI: 10.1016/j.ccm.2012.09.006.
Newly Recognized Occupational and Environmental Causes of Chronic Terminal Airways and Parenchymal Lung DiseaseSauler M, Gulati M. Newly Recognized Occupational and Environmental Causes of Chronic Terminal Airways and Parenchymal Lung Disease. Clinics In Chest Medicine 2012, 33: 667-680. PMID: 23153608, PMCID: PMC3515663, DOI: 10.1016/j.ccm.2012.09.002.
Chitinase 1 Is a Biomarker for and Therapeutic Target in Scleroderma-Associated Interstitial Lung Disease That Augments TGF-β1 SignalingLee CG, Herzog EL, Ahangari F, Zhou Y, Gulati M, Lee CM, Peng X, Feghali-Bostwick C, Jimenez SA, Varga J, Elias JA. Chitinase 1 Is a Biomarker for and Therapeutic Target in Scleroderma-Associated Interstitial Lung Disease That Augments TGF-β1 Signaling. The Journal Of Immunology 2012, 189: 2635-2644. PMID: 22826322, PMCID: PMC4336775, DOI: 10.4049/jimmunol.1201115.
Role of semaphorin 7a signaling in transforming growth factor β1–induced lung fibrosis and scleroderma‐related interstitial lung diseaseGan Y, Reilkoff R, Peng X, Russell T, Chen Q, Mathai SK, Homer R, Gulati M, Siner J, Elias J, Bucala R, Herzog E. Role of semaphorin 7a signaling in transforming growth factor β1–induced lung fibrosis and scleroderma‐related interstitial lung disease. Arthritis & Rheumatism 2011, 63: 2484-2494. PMID: 21484765, PMCID: PMC3651701, DOI: 10.1002/art.30386.
Local apoptosis promotes collagen production by monocyte-derived cells in transforming growth factor β1-induced lung fibrosisPeng X, Mathai SK, Murray LA, Russell T, Reilkoff R, Chen Q, Gulati M, Elias JA, Bucala R, Gan Y, Herzog EL. Local apoptosis promotes collagen production by monocyte-derived cells in transforming growth factor β1-induced lung fibrosis. Fibrogenesis & Tissue Repair 2011, 4: 12. PMID: 21586112, PMCID: PMC3123188, DOI: 10.1186/1755-1536-4-12.
Semaphorin 7A Expression On Lymphocytes Promotes Alternative Macrophage Activation In Murine Models Of Lung Fibrosis And Human IPFReilkoff R, Russell T, Peng X, Gulati M, Homer R, Elias J, Herzog E. Semaphorin 7A Expression On Lymphocytes Promotes Alternative Macrophage Activation In Murine Models Of Lung Fibrosis And Human IPF. 2011, a5575-a5575. DOI: 10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5575.
Diagnostic assessment of patients with interstitial lung diseaseGulati M. Diagnostic assessment of patients with interstitial lung disease. Npj Primary Care Respiratory Medicine 2011, 20: 120-127. PMID: 21509417, PMCID: PMC6549811, DOI: 10.4104/pcrj.2010.00079.
TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid PMurray LA, Chen Q, Kramer MS, Hesson DP, Argentieri RL, Peng X, Gulati M, Homer RJ, Russell T, van Rooijen N, Elias JA, Hogaboam CM, Herzog EL. TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P. The International Journal Of Biochemistry & Cell Biology 2010, 43: 154-162. PMID: 21044893, DOI: 10.1016/j.biocel.2010.10.013.
Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotypeMathai SK, Gulati M, Peng X, Russell TR, Shaw AC, Rubinowitz AN, Murray LA, Siner JM, Antin-Ozerkis DE, Montgomery RR, Reilkoff RA, Bucala RJ, Herzog EL. Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype. Laboratory Investigation 2010, 90: 812-823. PMID: 20404807, PMCID: PMC3682419, DOI: 10.1038/labinvest.2010.73.
Serum Amyloid P Therapeutically Attenuates Murine Bleomycin-Induced Pulmonary Fibrosis via Its Effects on MacrophagesMurray LA, Rosada R, Moreira AP, Joshi A, Kramer MS, Hesson DP, Argentieri RL, Mathai S, Gulati M, Herzog EL, Hogaboam CM. Serum Amyloid P Therapeutically Attenuates Murine Bleomycin-Induced Pulmonary Fibrosis via Its Effects on Macrophages. PLOS ONE 2010, 5: e9683. PMID: 20300636, PMCID: PMC2837381, DOI: 10.1371/journal.pone.0009683.
Longitudinal Decline in FEV1 by GOLD Stage in Workers in a Spirometry Surveillance Program.Gulati M, Slade M, Galusha D, Redlich C, Cullen M. Longitudinal Decline in FEV1 by GOLD Stage in Workers in a Spirometry Surveillance Program. 2009, a4078. DOI: 10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4078.
Healthcare for Obstructive Lung Disease in an Industrial Spirometry Surveillance ProgramGulati M, Slade MD, Fiellin MG, Cullen MR. Healthcare for Obstructive Lung Disease in an Industrial Spirometry Surveillance Program. Journal Of Occupational And Environmental Medicine 2009, 51: 336-342. PMID: 19225419, PMCID: PMC3711683, DOI: 10.1097/jom.0b013e3181954ae6.
Lung Diseases, OccupationalGulati M, Cullen M. Lung Diseases, Occupational. 2008, 157-163. DOI: 10.1016/b978-012373960-5.00298-7.
Clinical profile, diagnosis and management of patients presenting with symptomatic pulmonary embolism.Agarwal R, Gulati M, Mittal B, Jindal S. Clinical profile, diagnosis and management of patients presenting with symptomatic pulmonary embolism. The Indian Journal Of Chest Diseases & Allied Sciences 2006, 48: 111-4. PMID: 16696525.
Risk Factors for Tuberculin Skin Test Positivity in an Industrial Workforce Results of a Contact InvestigationGulati M, Liss DJ, Sparer JA, Slade MD, Holt EW, Rabinowitz PM. Risk Factors for Tuberculin Skin Test Positivity in an Industrial Workforce Results of a Contact Investigation. Journal Of Occupational And Environmental Medicine 2005, 47: 1190-1199. PMID: 16282881, DOI: 10.1097/01.jom.0000183098.29627.47.
Chapter 19 Diseases of the Lung and PleuraWeir N, Gulati M, Redlich C, Tarlo S, Chan-Yeung M, Schachter E, Kennedy S, Schwartz D, Glazer C, Rose C, Balmes J, Brodkin C, Rosenstock L, Banks D, Petsonk E, Attfield M, Donovan J, Lockey J. Chapter 19 Diseases of the Lung and Pleura. 2005, 285-417. DOI: 10.1016/b978-0-7216-8974-6.50023-3.
The World Trade Center Residents’ Respiratory Health Study: New-Onset Respiratory Symptoms and Pulmonary FunctionReibman J, Lin S, Hwang SA, Gulati M, Bowers JA, Rogers L, Berger KI, Hoerning A, Gomez M, Fitzgerald EF. The World Trade Center Residents’ Respiratory Health Study: New-Onset Respiratory Symptoms and Pulmonary Function. Environmental Health Perspectives 2004, 113: 406-411. PMID: 15811830, PMCID: PMC1278479, DOI: 10.1289/ehp.7375.
Impatient Inpatient CareGulati M, Saint S, Tierney L. Impatient Inpatient Care. New England Journal Of Medicine 2000, 342: 37-40. PMID: 10620648, DOI: 10.1056/nejm200001063420107.

Clinical Trials

Conditions	Study Title
Diseases of the Cardiovascular System; Diseases of the Kidney & Urinary Tract; Genetics - Adult	Genetic Determinants of Aneurysms in Autosomal Dominant Polycystic Kidney Disease
Immune System; Rheumatology/Scleroderma	Pathogenic Wnt-beta catenin target genes in macrophages and fibrosis

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