Phillip Joseph, MD
Assistant Professor; Associate Director, Pulmonary Vascular Disease Program
Research & Publications
Biography
News
Coauthors
Selected Publications
- Post-Acute Sequelae of SARS-CoV-2 More Than DeconditioningJoseph P, Singh I. Post-Acute Sequelae of SARS-CoV-2 More Than Deconditioning. CHEST Journal 2023, 164: 583-584. PMID: 37689472, DOI: 10.1016/j.chest.2023.03.014.
- Integrating Right Ventricular Pressure Waveform Analysis With Two-Point Volume Measurement for Quantification of Systolic and Diastolic Function: Experimental Validation and Clinical ApplicationHeerdt P, Martin-Flores M, Oakland H, Joseph P, Singh I. Integrating Right Ventricular Pressure Waveform Analysis With Two-Point Volume Measurement for Quantification of Systolic and Diastolic Function: Experimental Validation and Clinical Application. Journal Of Cardiothoracic And Vascular Anesthesia 2023, 37: 1929-1937. PMID: 37422337, PMCID: PMC10529383, DOI: 10.1053/j.jvca.2023.06.011.
- Sex Differences in Hemodynamic Response to Exercise in Patients With Myalgic Encephalomyelitis: Insights From Invasive Cardiopulmonary Exercise TestingWichmann Madsen K, Squires J, Stovall M, Al-Zayer S, Chang C, Xiao W, Pari R, Joseph P, Systrom D. Sex Differences in Hemodynamic Response to Exercise in Patients With Myalgic Encephalomyelitis: Insights From Invasive Cardiopulmonary Exercise Testing. 2023, a2995-a2995. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2995.
- Proteomic profiling demonstrates inflammatory and endotheliopathy signatures associated with impaired cardiopulmonary exercise hemodynamic profile in Post Acute Sequelae of SARS‐CoV‐2 infection (PASC) syndromeSingh I, Leitner B, Wang Y, Zhang H, Joseph P, Lutchmansingh D, Gulati M, Possick J, Damsky W, Hwa J, Heerdt P, Chun H. Proteomic profiling demonstrates inflammatory and endotheliopathy signatures associated with impaired cardiopulmonary exercise hemodynamic profile in Post Acute Sequelae of SARS‐CoV‐2 infection (PASC) syndrome. Pulmonary Circulation 2023, 13: e12220. PMID: 37091121, PMCID: PMC10113513, DOI: 10.1002/pul2.12220.
- Exercise Pathophysiology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Postacute Sequelae of SARS-CoV-2 More in Common Than Not?Joseph P, Singh I, Oliveira R, Capone C, Mullen M, Cook D, Stovall M, Squires J, Madsen K, Waxman A, Systrom D. Exercise Pathophysiology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Postacute Sequelae of SARS-CoV-2 More in Common Than Not? CHEST Journal 2023, 164: 717-726. PMID: 37054777, PMCID: PMC10088277, DOI: 10.1016/j.chest.2023.03.049.
- Response to letter to the editor “noninvasive determinants of pulmonary hypertension in interstitial lung disease”Joseph P, Savarimuthu S, Oakland H, Cullinan M, Heerdt P, Singh I. Response to letter to the editor “noninvasive determinants of pulmonary hypertension in interstitial lung disease”. Pulmonary Circulation 2023, 13: e12238. PMID: 37180828, PMCID: PMC10166920, DOI: 10.1002/pul2.12238.
- Noninvasive determinants of pulmonary hypertension in interstitial lung diseaseJoseph P, Savarimuthu S, Zhao J, Yan X, Oakland H, Cullinan M, Heerdt P, Singh I. Noninvasive determinants of pulmonary hypertension in interstitial lung disease. Pulmonary Circulation 2023, 13: e12197. PMID: 36814586, PMCID: PMC9939578, DOI: 10.1002/pul2.12197.
- Short- and long-term noninvasive cardiopulmonary exercise assessment in previously hospitalised COVID-19 patientsSingh I, Joseph P. Short- and long-term noninvasive cardiopulmonary exercise assessment in previously hospitalised COVID-19 patients. European Respiratory Journal 2022, 61: 2201739. PMID: 36137592, PMCID: PMC9515479, DOI: 10.1183/13993003.01739-2022.
- Neurovascular Dysregulation and Acute Exercise Intolerance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome A Randomized, Placebo-Controlled Trial of PyridostigmineJoseph P, Pari R, Miller S, Warren A, Stovall MC, Squires J, Chang CJ, Xiao W, Waxman AB, Systrom DM. Neurovascular Dysregulation and Acute Exercise Intolerance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome A Randomized, Placebo-Controlled Trial of Pyridostigmine. CHEST Journal 2022, 162: 1116-1126. PMID: 35526605, DOI: 10.1016/j.chest.2022.04.146.
- Impaired Stressed Blood Volume Augmentation in Post-COVID-19 PatientsSavarimuthu S, Joseph P, Lutchmansingh D, Possick J, Gulati M, Cullinan M, Kreiger J, Heerdt P, Singh I. Impaired Stressed Blood Volume Augmentation in Post-COVID-19 Patients. 2022, a5418-a5418. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5418.
- Acute Effect of Pyridostigmine in Exertional Intolerance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Randomized Placebo-Controlled Clinical TrialStovall M, Joseph P, Pari R, Warren A, Miller S, Squires J, Xiao W, Waxman A, Systrom D. Acute Effect of Pyridostigmine in Exertional Intolerance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Randomized Placebo-Controlled Clinical Trial. 2022, a2063-a2063. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2063.
- Right Ventricular Capacitance in Pulmonary Arterial Hypertension and Heart Failure with Preserved Ejection FractionOakland H, Sugeng L, Joseph P, Izzi D, Zalik F, Raza A, Amendola R, Heerdt P, Singh I. Right Ventricular Capacitance in Pulmonary Arterial Hypertension and Heart Failure with Preserved Ejection Fraction. 2022, a4423-a4423. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a4423.
- Reply to Grignola and TrujilloOakland HT, Joseph P, Naeije R, Elassal A, Cullinan M, Heerdt PM, Singh I. Reply to Grignola and Trujillo. Journal Of Applied Physiology 2022, 132: 219-219. PMID: 35030044, PMCID: PMC8759952, DOI: 10.1152/japplphysiol.00810.2021.
- Cardiopulmonary Exercise Testing in Pulmonary Vascular DiseaseJoseph P, Systrom D. Cardiopulmonary Exercise Testing in Pulmonary Vascular Disease. 2022, 582-596. DOI: 10.1016/b978-0-12-801238-3.11478-3.
- Abstract 6991: Impaired Systemic Oxygen Extraction Relates to Reduced Exercise Capacity in Post-COVID-19 Long Hauler SyndromeBiondi M, Joseph P, Gulati M, Possick J, Lutchmansingh D, Cullinan M, Heerdt P, Singh I. Abstract 6991: Impaired Systemic Oxygen Extraction Relates to Reduced Exercise Capacity in Post-COVID-19 Long Hauler Syndrome. Circulation 2021, 144: a6991-a6991. DOI: 10.1161/circ.144.suppl_1.6991.
- Abstract 10486: Single-Beat Estimation Right Ventricular End Diastolic Pressure RelationshipOakland H, Sugeng L, Joseph P, Amendola R, Crandall I, Raza A, Izzi D, Zalik F, Elassal A, Heerdt P, Singh I. Abstract 10486: Single-Beat Estimation Right Ventricular End Diastolic Pressure Relationship. Circulation 2021, 144: a10486-a10486. DOI: 10.1161/circ.144.suppl_1.10486.
- UNEXPLAINED DYSPNEA IN A PATIENT WITH A HISTORY OF COVID-19Biondi M, Gulati M, Possick J, Joseph P, Singh I, Lutchmansingh D. UNEXPLAINED DYSPNEA IN A PATIENT WITH A HISTORY OF COVID-19. CHEST Journal 2021, 160: a2373-a2374. PMCID: PMC8503500, DOI: 10.1016/j.chest.2021.07.2054.
- Sex Differences and the Role of Sex Hormones in Pulmonary HypertensionOakland HT, Joseph P. Sex Differences and the Role of Sex Hormones in Pulmonary Hypertension. Clinics In Chest Medicine 2021, 42: 457-465. PMID: 34353451, DOI: 10.1016/j.ccm.2021.04.006.
- Persistent Exertional Intolerance After COVID-19 Insights From Invasive Cardiopulmonary Exercise TestingSingh I, Joseph P, Heerdt PM, Cullinan M, Lutchmansingh DD, Gulati M, Possick JD, Systrom DM, Waxman AB. Persistent Exertional Intolerance After COVID-19 Insights From Invasive Cardiopulmonary Exercise Testing. CHEST Journal 2021, 161: 54-63. PMID: 34389297, PMCID: PMC8354807, DOI: 10.1016/j.chest.2021.08.010.
- Arterial load and right ventricular-vascular coupling in pulmonary hypertensionOakland H, Joseph P, Naeije R, Elassal A, Cullinan M, Heerdt PM, Singh I. Arterial load and right ventricular-vascular coupling in pulmonary hypertension. Journal Of Applied Physiology 2021, 131: 424-433. PMID: 34043473, PMCID: PMC8325619, DOI: 10.1152/japplphysiol.00204.2021.
- Characteristic Impedance Affects Global Right Ventricular Function in Pulmonary Arterial Hypertension and Heart Failure with Preserved Ejection FractionOakland H, Joseph P, Elassal A, Cullinan M, Heerdt P, Singh I. Characteristic Impedance Affects Global Right Ventricular Function in Pulmonary Arterial Hypertension and Heart Failure with Preserved Ejection Fraction. 2021, a3690-a3690. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a3690.
- Insights From Invasive Cardiopulmonary Exercise Testing of Patients With Myalgic Encephalomyelitis/Chronic Fatigue SyndromeJoseph P, Arevalo C, Oliveira RKF, Faria-Urbina M, Felsenstein D, Oaklander AL, Systrom DM. Insights From Invasive Cardiopulmonary Exercise Testing of Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. CHEST Journal 2021, 160: 642-651. PMID: 33577778, PMCID: PMC8727854, DOI: 10.1016/j.chest.2021.01.082.
- The Evolution in Nomenclature, Diagnosis, and Classification of Pulmonary HypertensionFouad J, Joseph P. The Evolution in Nomenclature, Diagnosis, and Classification of Pulmonary Hypertension. Clinics In Chest Medicine 2021, 42: 1-8. PMID: 33541603, DOI: 10.1016/j.ccm.2020.11.012.
- CHARACTERISTICS AND OUTCOMES OF PATIENTS WITH COVID-19 WITH RESPIRATORY FAILURE REQUIRING EXTRACORPOREAL MEMBRANE OXYGENATIONFouad J, Singh I, Khosla A, Szabo C, Tantawy H, Razo-Vazquez A, Geirsson A, Bonde P, Fajardo E, Joseph P, Siner J, Chichra A. CHARACTERISTICS AND OUTCOMES OF PATIENTS WITH COVID-19 WITH RESPIRATORY FAILURE REQUIRING EXTRACORPOREAL MEMBRANE OXYGENATION. CHEST Journal 2020, 158: a703-a704. PMCID: PMC7548617, DOI: 10.1016/j.chest.2020.08.660.
- Diagnostic utility of sub‐maximum cardiopulmonary exercise testing in the ambulatory setting for heart failure with preserved ejection fractionOakland HT, Joseph P, Elassal A, Cullinan M, Heerdt PM, Singh I. Diagnostic utility of sub‐maximum cardiopulmonary exercise testing in the ambulatory setting for heart failure with preserved ejection fraction. Pulmonary Circulation 2020, 10: 1-10. PMID: 33282205, PMCID: PMC7691918, DOI: 10.1177/2045894020972273.
- Fick principle and exercise pulmonary hemodynamic determinants of the six‐minute walk distance in pulmonary hypertensionJoseph P, Oliveira RKF, Eslam RB, Agarwal M, Waxman AB, Systrom DM. Fick principle and exercise pulmonary hemodynamic determinants of the six‐minute walk distance in pulmonary hypertension. Pulmonary Circulation 2020, 10: 1-9. PMID: 32994925, PMCID: PMC7502687, DOI: 10.1177/2045894020957576.
- Cardiopulmonary Exercise Testing in Pulmonary Vascular DiseaseJoseph P, Systrom DM. Cardiopulmonary Exercise Testing in Pulmonary Vascular Disease . In: Encyclopedia of Respiratory Medicine, 2e. 2 ed. Peacock A, editor. United Kingdom: Elsevier; 2020.
- Lysophosphatidic acid and apolipoprotein A1 predict increased risk of developing World Trade Center-lung injury: a nested case-control study.Tsukiji J, Cho SJ, Echevarria GC, Kwon S, Joseph P, Schenck EJ, Naveed B, Prezant DJ, Rom WN, Schmidt AM, Weiden MD, Nolan A. Lysophosphatidic acid and apolipoprotein A1 predict increased risk of developing World Trade Center-lung injury: a nested case-control study. Biomarkers : Biochemical Indicators Of Exposure, Response, And Susceptibility To Chemicals 2014, 19: 159-65. PMID: 24548082, PMCID: PMC4306444, DOI: 10.3109/1354750X.2014.891047.
Clinical Trials
| Conditions | Study Title |
|---|---|
| Diseases of the Cardiovascular System; Hypertension | A Study of Sotatercept for the Treatment of Cpc-PH Due to HFpEF (MK-7962-007/A011-16) (CADENCE) |