Maor Sauler, MD

• Adam V Wisnewski
• Albert Ko
• Asawari Korde
• Buqu Hu
• Clemente Britto-Leon
• Daniel Greif
• David N. Assis
• David Stitelman
• Edward Manning
• Emanuela Bruscia
• Farida Ahangari
• Francis Lee
• Gail Stanley
• Heather Allore
• Hong-Jai Park
• Hongyu Zhao
• Inderjit Singh
• Isabel Bazan
• Jeanette Tetrault
• Jen-hwa Chu
• Jennefer Par-Young
• Jian Liu
• Jianlei Gu
• Jon Koff
• Jonas Christian Schupp
• Jose Gomez Villalobos
• Junghee Jenny Shin
• Lawrence Young
• Margaret Pisani
• Marie Egan
• Mark David Siegel
• Martin Slade
• Maurizio Chioccioli
• Micha Sam Brickman Raredon
• Min-Jong Kang
• Mridu Gulati
• Naftali Kaminski
• Nicole Grant
• Richard Bucala
• Richard Pierce
• Robert Homer
• Ruth R Montgomery
• Sang-Hun Kim
• Taylor Adams
• Terence Trow
• Wade Schulz
• Won Jae Huh
• Xiting Yan
• Xuchen Zhang

Aging; Emphysema; Lung Diseases; Respiratory Distress Syndrome; Frail Elderly; Lung Injury

• Macrophage migration inhibitory factor deficiency in chronic obstructive pulmonary diseaseSauler M, Leng L, Trentalange M, Haslip M, Shan P, Piecychna M, Zhang Y, Andrews N, Mannam P, Allore H, Fried T, Bucala R, Lee PJ. Macrophage migration inhibitory factor deficiency in chronic obstructive pulmonary disease. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2014, 306: l487-l496. PMID: 24441872, PMCID: PMC3949087, DOI: 10.1152/ajplung.00284.2013.
• Endothelial CD74 mediates macrophage migration inhibitory factor protection in hyperoxic lung injurySauler M, Zhang Y, Min J, Leng L, Shan P, Roberts S, Jorgensen WL, Bucala R, Lee PJ. Endothelial CD74 mediates macrophage migration inhibitory factor protection in hyperoxic lung injury. The FASEB Journal 2015, 29: 1940-1949. PMID: 25609432, PMCID: PMC4415022, DOI: 10.1096/fj.14-260299.
• The DNA repair transcriptome in severe COPDSauler M, Lamontagne M, Finnemore E, Herazo-Maya JD, Tedrow J, Zhang X, Morneau JE, Sciurba F, Timens W, Paré PD, Lee PJ, Kaminski N, Bossé Y, Gomez JL. The DNA repair transcriptome in severe COPD. European Respiratory Journal 2018, 52: 1701994. PMID: 30190272, PMCID: PMC6422831, DOI: 10.1183/13993003.01994-2017.
• MicroRNA miR-24-3p reduces DNA damage responses, apoptosis, and susceptibility to chronic obstructive pulmonary diseaseNouws J, Wan F, Finnemore E, Roque W, Kim SJ, Bazan IS, Li CX, Sköld C, Dai Q, Yan X, Chioccioli M, Neumeister V, Britto CJ, Sweasy J, Bindra RS, Wheelock ÅM, Gomez JL, Kaminski N, Lee PJ, Sauler M. MicroRNA miR-24-3p reduces DNA damage responses, apoptosis, and susceptibility to chronic obstructive pulmonary disease. JCI Insight 2021, 6: e134218. PMID: 33290275, PMCID: PMC7934877, DOI: 10.1172/jci.insight.134218.
• Characterization of the COPD alveolar niche using single-cell RNA sequencingSauler M, McDonough JE, Adams TS, Kothapalli N, Barnthaler T, Werder RB, Schupp JC, Nouws J, Robertson MJ, Coarfa C, Yang T, Chioccioli M, Omote N, Cosme C, Poli S, Ayaub EA, Chu SG, Jensen KH, Gomez JL, Britto CJ, Raredon MSB, Niklason LE, Wilson AA, Timshel PN, Kaminski N, Rosas IO. Characterization of the COPD alveolar niche using single-cell RNA sequencing. Nature Communications 2022, 13: 494. PMID: 35078977, PMCID: PMC8789871, DOI: 10.1038/s41467-022-28062-9.
• Cell Death in the Lung: The Apoptosis–Necroptosis AxisSauler M, Bazan IS, Lee PJ. Cell Death in the Lung: The Apoptosis–Necroptosis Axis. Annual Review Of Physiology 2018, 81: 1-28. PMID: 30485762, PMCID: PMC6598441, DOI: 10.1146/annurev-physiol-020518-114320.
• A functional macrophage migration inhibitory factor promoter polymorphism is associated with reduced diffusing capacityZhang C, Ramsey C, Berical A, Yu L, Leng L, McGinnis K, Song Y, Michael H, McCormack M, Allore H, Morris A, Crothers K, Bucala R, Lee P, Sauler M. A functional macrophage migration inhibitory factor promoter polymorphism is associated with reduced diffusing capacity. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2018, 316: l400-l405. PMID: 30520689, PMCID: PMC6397351, DOI: 10.1152/ajplung.00439.2018.
• Spatial Transcriptomics Resolve an Emphysema-Specific Lymphoid Follicle B Cell Signature in Chronic Obstructive Pulmonary DiseaseRojas-Quintero J, Ochsner S, New F, Divakar P, Yang C, Wu T, Robinson J, Chandrashekar D, Banovich N, Rosas I, Sauler M, Kheradmand F, Gaggar A, Margaroli C, San Jose Estepar R, McKenna N, Polverino F. Spatial Transcriptomics Resolve an Emphysema-Specific Lymphoid Follicle B Cell Signature in Chronic Obstructive Pulmonary Disease. American Journal Of Respiratory And Critical Care Medicine 2024, 209: 48-58. PMID: 37934672, PMCID: PMC10870877, DOI: 10.1164/rccm.202303-0507le.
• Cigarette Smoking and the Airway Epithelium: Characterizing Changes in Gene Expression over TimeCastaldi P, Sauler M. Cigarette Smoking and the Airway Epithelium: Characterizing Changes in Gene Expression over Time. American Journal Of Respiratory And Critical Care Medicine 2023, 208: 749-750. PMID: 37610776, PMCID: PMC10563183, DOI: 10.1164/rccm.202308-1371ed.
• Alveolar type II epithelial cell FASN maintains lipid homeostasis in experimental COPDFan L, McConn K, Plataki M, Kenny S, Williams N, Kim K, Quirke J, Chen Y, Sauler M, Möbius M, Chung K, Gomez E, Choi A, Xu J, Cloonan S. Alveolar type II epithelial cell FASN maintains lipid homeostasis in experimental COPD. JCI Insight 2023, 8: e163403. PMID: 37606038, PMCID: PMC10543729, DOI: 10.1172/jci.insight.163403.
• A statistical framework to identify cell types whose genetically regulated proportions are associated with complex diseasesLiu W, Deng W, Chen M, Dong Z, Zhu B, Yu Z, Tang D, Sauler M, Lin C, Wain L, Cho M, Kaminski N, Zhao H. A statistical framework to identify cell types whose genetically regulated proportions are associated with complex diseases. PLOS Genetics 2023, 19: e1010825. PMID: 37523391, PMCID: PMC10414598, DOI: 10.1371/journal.pgen.1010825.
• VISTA (PD-1H) Is a Crucial Immune Regulator to Limit Pulmonary Fibrosis.Kim S, Adams T, Hu Q, Shin H, Chae G, Lee S, Sharma L, Kwon H, Lee F, Park H, Huh W, Manning E, Kaminski N, Sauler M, Chen L, Song J, Kim T, Kang M. VISTA (PD-1H) Is a Crucial Immune Regulator to Limit Pulmonary Fibrosis. American Journal Of Respiratory Cell And Molecular Biology 2023, 69: 22-33. PMID: 36450109, PMCID: PMC10324045, DOI: 10.1165/rcmb.2022-0219oc.
• Taking Small Airways in Chronic Obstructive Pulmonary Disease to TASCSauler M, Hackett T. Taking Small Airways in Chronic Obstructive Pulmonary Disease to TASC. American Journal Of Respiratory And Critical Care Medicine 2023, 207: 1114-1115. PMID: 36821491, PMCID: PMC10161754, DOI: 10.1164/rccm.202302-0295ed.
• In utero delivery of miRNA induces epigenetic alterations and corrects pulmonary pathology in congenital diaphragmatic herniaUllrich S, Yung N, Bauer-Pisani T, Maassel N, Guerra M, Freedman-Weiss M, Ahle S, Ricciardi A, Sauler M, Saltzman W, Piotrowski-Daspit A, Stitelman D. In utero delivery of miRNA induces epigenetic alterations and corrects pulmonary pathology in congenital diaphragmatic hernia. Molecular Therapy - Nucleic Acids 2023, 32: 594-602. PMID: 37200861, PMCID: PMC10185702, DOI: 10.1016/j.omtn.2023.04.018.
• Reply to SureshBazan I, Kim S, Ardito T, Zhang Y, Shan P, Sauler M, Lee P. Reply to Suresh. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2022, 323: l648-l649. PMID: 36351165, PMCID: PMC9662795, DOI: 10.1152/ajplung.00294.2022.
• A lung targeted miR-29 mimic as a therapy for pulmonary fibrosisChioccioli M, Roy S, Newell R, Pestano L, Dickinson B, Rigby K, Herazo-Maya J, Jenkins G, Ian S, Saini G, Johnson SR, Braybrooke R, Yu G, Sauler M, Ahangari F, Ding S, DeIuliis J, Aurelien N, Montgomery RL, Kaminski N. A lung targeted miR-29 mimic as a therapy for pulmonary fibrosis. EBioMedicine 2022, 85: 104304. PMID: 36265417, PMCID: PMC9587275, DOI: 10.1016/j.ebiom.2022.104304.
• MIF is a Common Genetic Determinant of COVID-19 Symptomatic Infection and SeverityShin JJ, Fan W, Par-Young J, Piecychna M, Leng L, Israni-Winger K, Qing H, Gu J, Zhao H, Schulz WL, Unlu S, Kuster J, Young G, Liu J, Ko AI, Garcia A, Sauler M, Wisnewski AV, Young L, Orduña A, Wang A, Klementina O, Garcia AB, Hegyi P, Armstrong ME, Mitchell P, Ordiz DB, Garami A, Kang I, Bucala R. MIF is a Common Genetic Determinant of COVID-19 Symptomatic Infection and Severity. QJM 2022, 116: hcac234. PMID: 36222594, PMCID: PMC9620729, DOI: 10.1093/qjmed/hcac234.
• Epidermal Growth Factor Receptor Inhibition Is Protective in Hyperoxia-Induced Lung InjuryHarris ZM, Sun Y, Joerns J, Clark B, Hu B, Korde A, Sharma L, Shin HJ, Manning EP, Placek L, Unutmaz D, Stanley G, Chun H, Sauler M, Rajagopalan G, Zhang X, Kang MJ, Koff JL. Epidermal Growth Factor Receptor Inhibition Is Protective in Hyperoxia-Induced Lung Injury. Oxidative Medicine And Cellular Longevity 2022, 2022: 9518592. PMID: 36193076, PMCID: PMC9526641, DOI: 10.1155/2022/9518592.
• Lung Spatial Profiling Reveals a T Cell Signature in COPD Patients with Fatal SARS-CoV-2 InfectionYang CX, Tomchaney M, Landecho MF, Zamacona BR, Oto M, Zulueta J, Malo J, Knoper S, Contoli M, Papi A, Vasilescu DM, Sauler M, Straub C, Tan C, Martinez FD, Bhattacharya D, Rosas IO, Kheradmand F, Hackett TL, Polverino F. Lung Spatial Profiling Reveals a T Cell Signature in COPD Patients with Fatal SARS-CoV-2 Infection. Cells 2022, 11: 1864. PMID: 35740993, PMCID: PMC9220844, DOI: 10.3390/cells11121864.
• Untargeted metabolomics analysis of esophageal squamous cell cancer progressionYang T, Hui R, Nouws J, Sauler M, Zeng T, Wu Q. Untargeted metabolomics analysis of esophageal squamous cell cancer progression. Journal Of Translational Medicine 2022, 20: 127. PMID: 35287685, PMCID: PMC8919643, DOI: 10.1186/s12967-022-03311-z.
• Compromised Cardiopulmonary Function in Fibulin-5 Deficient Mice.Ramachandra AB, Mikush N, Sauler M, Humphrey JD, Manning EP. Compromised Cardiopulmonary Function in Fibulin-5 Deficient Mice. Journal Of Biomechanical Engineering 2022, 144 PMID: 35171214, PMCID: PMC8990734, DOI: 10.1115/1.4053873.
• Sex differences and altered mitophagy in experimental pulmonary hypertensionBazan IS, Kim SJ, Ardito TA, Zhang Y, Shan P, Sauler M, Lee P. Sex differences and altered mitophagy in experimental pulmonary hypertension. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2022, 322: l761-l769. PMID: 35137625, PMCID: PMC9076415, DOI: 10.1152/ajplung.00019.2020.
• Characterization of pulmonary vascular remodeling and MicroRNA-126-targets in COPD-pulmonary hypertensionGoel K, Egersdorf N, Gill A, Cao D, Collum S, Jyothula S, Huang H, Sauler M, Lee P, Majka S, Karmouty-Quintana H, Petrache I. Characterization of pulmonary vascular remodeling and MicroRNA-126-targets in COPD-pulmonary hypertension. Respiratory Research 2022, 23: 349. PMID: 36522710, PMCID: PMC9756782, DOI: 10.1186/s12931-022-02267-4.
• MIF but not MIF-2 recruits inflammatory macrophages in an experimental polymicrobial sepsis modelTilstam PV, Schulte W, Holowka T, Kim BS, Nouws J, Sauler M, Piecychna M, Pantouris G, Lolis E, Leng L, Bernhagen J, Fingerle-Rowson G, Bucala R. MIF but not MIF-2 recruits inflammatory macrophages in an experimental polymicrobial sepsis model. Journal Of Clinical Investigation 2021, 131: e127171. PMID: 34850744, PMCID: PMC8631602, DOI: 10.1172/jci127171.
• Leveraging ageing models of pulmonary fibrosis: the efficacy of nintedanib in ageingKato K, Shin YJ, Palumbo S, Papageorgiou I, Hahn S, Irish JD, Rounseville SP, Krafty RT, Wollin L, Sauler M, Hecker L. Leveraging ageing models of pulmonary fibrosis: the efficacy of nintedanib in ageing. European Respiratory Journal 2021, 58: 2100759. PMID: 34531276, PMCID: PMC8613836, DOI: 10.1183/13993003.00759-2021.
• Metformin: Experimental and Clinical Evidence for a Potential Role in Emphysema Treatment.Polverino F, Wu TD, Rojas-Quintero J, Wang X, Mayo J, Tomchaney M, Tram J, Packard S, Zhang D, Cleveland KH, Cordoba-Lanus E, Owen CA, Fawzy A, Kinney GL, Hersh CP, Hansel NN, Doubleday K, Sauler M, Tesfaigzi Y, Ledford JG, Casanova C, Zmijewski J, Konhilas J, Langlais PR, Schnellmann R, Rahman I, McCormack M, Celli B. Metformin: Experimental and Clinical Evidence for a Potential Role in Emphysema Treatment. American Journal Of Respiratory And Critical Care Medicine 2021, 204: 651-666. PMID: 34033525, PMCID: PMC8521702, DOI: 10.1164/rccm.202012-4510oc.
• Integrated Single-Cell Atlas of Endothelial Cells of the Human LungSchupp JC, Adams TS, Cosme C, Raredon MSB, Yuan Y, Omote N, Poli S, Chioccioli M, Rose KA, Manning EP, Sauler M, DeIuliis G, Ahangari F, Neumark N, Habermann AC, Gutierrez AJ, Bui LT, Lafyatis R, Pierce RW, Meyer KB, Nawijn MC, Teichmann SA, Banovich NE, Kropski JA, Niklason LE, Pe’er D, Yan X, Homer RJ, Rosas IO, Kaminski N. Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung. Circulation 2021, 144: 286-302. PMID: 34030460, PMCID: PMC8300155, DOI: 10.1161/circulationaha.120.052318.
• SPLUNC1: a novel marker of cystic fibrosis exacerbationsKhanal S, Webster M, Niu N, Zielonka J, Nunez M, Chupp G, Slade MD, Cohn L, Sauler M, Gomez JL, Tarran R, Sharma L, Dela Cruz CS, Egan M, Laguna T, Britto CJ. SPLUNC1: a novel marker of cystic fibrosis exacerbations. European Respiratory Journal 2021, 58: 2000507. PMID: 33958427, PMCID: PMC8571118, DOI: 10.1183/13993003.00507-2020.
• Nintedanib Inhibits Pulmonary Fibrosis Development in Aged Mice but Does Not Reverse Age-Dependent Established FibrosisKato K, Shin Y, Irish J, Rounseville S, Sauler M, Wollin S, Hecker L. Nintedanib Inhibits Pulmonary Fibrosis Development in Aged Mice but Does Not Reverse Age-Dependent Established Fibrosis. 2021, a4425-a4425. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a4425.
• Lung Compliance Clusters of COVID-ARDS Identify Distinct Subgroups with Increased MortalityAlapaty S, Siner J, Sauler M, Baldassarri S, Davis J, Gomez J. Lung Compliance Clusters of COVID-ARDS Identify Distinct Subgroups with Increased Mortality. 2021, a2492-a2492. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2492.
• Single-cell characterization of a model of poly I:C-stimulated peripheral blood mononuclear cells in severe asthmaChen A, Diaz-Soto MP, Sanmamed MF, Adams T, Schupp JC, Gupta A, Britto C, Sauler M, Yan X, Liu Q, Nino G, Cruz CSD, Chupp GL, Gomez JL. Single-cell characterization of a model of poly I:C-stimulated peripheral blood mononuclear cells in severe asthma. Respiratory Research 2021, 22: 122. PMID: 33902571, PMCID: PMC8074196, DOI: 10.1186/s12931-021-01709-9.
• Macrophage-derived PDGF-B induces muscularization in murine and human pulmonary hypertensionNtokou A, Dave JM, Kauffman AC, Sauler M, Ryu C, Hwa J, Herzog EL, Singh I, Saltzman WM, Greif DM. Macrophage-derived PDGF-B induces muscularization in murine and human pulmonary hypertension. JCI Insight 2021, 6: e139067. PMID: 33591958, PMCID: PMC8026182, DOI: 10.1172/jci.insight.139067.
• Non-coding RNAs as Regulators of Cellular Senescence in Idiopathic Pulmonary Fibrosis and Chronic Obstructive Pulmonary DiseaseOmote N, Sauler M. Non-coding RNAs as Regulators of Cellular Senescence in Idiopathic Pulmonary Fibrosis and Chronic Obstructive Pulmonary Disease. Frontiers In Medicine 2020, 7: 603047. PMID: 33425948, PMCID: PMC7785852, DOI: 10.3389/fmed.2020.603047.
• Gene coexpression networks reveal novel molecular endotypes in alpha-1 antitrypsin deficiencyChu JH, Zang W, Vukmirovic M, Yan X, Adams T, DeIuliis G, Hu B, Mihaljinec A, Schupp JC, Becich MJ, Hochheiser H, Gibson KF, Chen ES, Morris A, Leader JK, Wisniewski SR, Zhang Y, Sciurba FC, Collman RG, Sandhaus R, Herzog EL, Patterson KC, Sauler M, Strange C, Kaminski N. Gene coexpression networks reveal novel molecular endotypes in alpha-1 antitrypsin deficiency. Thorax 2020, 76: 134-143. PMID: 33303696, PMCID: PMC10794043, DOI: 10.1136/thoraxjnl-2019-214301.
• Single-Cell Transcriptional Archetypes of Airway Inflammation in Cystic Fibrosis.Schupp JC, Khanal S, Gomez JL, Sauler M, Adams TS, Chupp GL, Yan X, Poli S, Zhao Y, Montgomery RR, Rosas IO, Dela Cruz CS, Bruscia EM, Egan ME, Kaminski N, Britto CJ. Single-Cell Transcriptional Archetypes of Airway Inflammation in Cystic Fibrosis. American Journal Of Respiratory And Critical Care Medicine 2020, 202: 1419-1429. PMID: 32603604, PMCID: PMC7667912, DOI: 10.1164/rccm.202004-0991oc.
• Macrophage Migration Inhibitory Factor is not Associated with Sarcoidosis Susceptibility or Severity in Whites or BlacksOdio CD, Miller EJ, Sauler M, Leng L, Piecychna M, Drake WP, Bucala R. Macrophage Migration Inhibitory Factor is not Associated with Sarcoidosis Susceptibility or Severity in Whites or Blacks. Sarcoidosis, Vasculitis, And Diffuse Lung Diseases 2020, 37: e2020003. PMID: 33264374, PMCID: PMC7690059, DOI: 10.36141/svdld.v37i3.9273.
• A Network of Sputum MicroRNAs is Associated with Neutrophilic Airway Inflammation in AsthmaGomez JL, Chen A, Diaz MP, Zirn N, Gupta A, Britto C, Sauler M, Yan X, Stewart E, Santerian K, Grant N, Liu Q, Fry R, Rager J, Cohn L, Alexis N, Chupp GL. A Network of Sputum MicroRNAs is Associated with Neutrophilic Airway Inflammation in Asthma. American Journal Of Respiratory And Critical Care Medicine 2020, 0: 51-64. PMID: 32255668, PMCID: PMC7328332, DOI: 10.1164/rccm.201912-2360oc.
• PECAM-1 is Associated WithOutcomes and Response to Treatment in Pulmonary Arterial HypertensionClapham KR, Rao Y, Sahay S, Sauler M, Lee PJ, Psotka MA, Fares WH, Ahmad T. PECAM-1 is Associated WithOutcomes and Response to Treatment in Pulmonary Arterial Hypertension. The American Journal Of Cardiology 2020, 127: 198-199. PMID: 32430164, DOI: 10.1016/j.amjcard.2020.04.031.
• Form, Function, and Dysfunction: Airway Diseases Are Associated With Increased Risk for Rheumatoid ArthritisSauler M. Form, Function, and Dysfunction: Airway Diseases Are Associated With Increased Risk for Rheumatoid Arthritis. Arthritis & Rheumatology 2020, 72: 699-701. PMID: 31876099, PMCID: PMC7188593, DOI: 10.1002/art.41193.
• Differential regulation of macrophage activation by the MIF cytokine superfamily members MIF and MIF‐2 in adipose tissue during endotoxemiaKim B, Tilstam PV, Arnke K, Leng L, Ruhl T, Piecychna M, Schulte W, Sauler M, Frueh FS, Storti G, Lindenblatt N, Giovanoli P, Pallua N, Bernhagen J, Bucala R. Differential regulation of macrophage activation by the MIF cytokine superfamily members MIF and MIF‐2 in adipose tissue during endotoxemia. The FASEB Journal 2020, 34: 4219-4233. PMID: 31961019, PMCID: PMC7060131, DOI: 10.1096/fj.201901511r.
• Endothelial toll‐like receptor 4 maintains lung integrity via epigenetic suppression of p16INK4aKim S, Shan P, Hwangbo C, Zhang Y, Min J, Zhang X, Ardito T, Li A, Peng T, Sauler M, Lee PJ. Endothelial toll‐like receptor 4 maintains lung integrity via epigenetic suppression of p16INK4a. Aging Cell 2019, 18: e12914. PMID: 30790400, PMCID: PMC6516428, DOI: 10.1111/acel.12914.
• BPIFA1 regulates lung neutrophil recruitment and interferon signaling during acute inflammationBritto CJ, Niu N, Khanal S, Huleihel L, Herazo-Maya J, Thompson A, Sauler M, Slade MD, Sharma L, Dela Cruz CS, Kaminski N, Cohn LE. BPIFA1 regulates lung neutrophil recruitment and interferon signaling during acute inflammation. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2018, 316: l321-l333. PMID: 30461288, PMCID: PMC6397348, DOI: 10.1152/ajplung.00056.2018.
• Endothelial cell‐secreted MIF reduces pericyte contractility and enhances neutrophil extravasationPellowe AS, Sauler M, Hou Y, Merola J, Liu R, Calderon B, Lauridsen HM, Harris MR, Leng L, Zhang Y, Tilstam PV, Pober JS, Bucala R, Lee PJ, Gonzalez AL. Endothelial cell‐secreted MIF reduces pericyte contractility and enhances neutrophil extravasation. The FASEB Journal 2018, 33: 2171-2186. PMID: 30252532, PMCID: PMC6338650, DOI: 10.1096/fj.201800480r.
• Complexity of macrophage migration inhibitory factor (MIF) and other angiogenic biomarkers profiling in pulmonary arterial hypertensionMarshall JD, Sauler M, Tonelli A, Rao Y, Bucala R, Lee PJ, Fares WH. Complexity of macrophage migration inhibitory factor (MIF) and other angiogenic biomarkers profiling in pulmonary arterial hypertension. Pulmonary Circulation 2017, 7: 730-733. PMID: 28714356, PMCID: PMC5841895, DOI: 10.1177/2045893217724141.
• MIF and Pulmonary DiseaseBaker T, Lee P, Sauler M. MIF and Pulmonary Disease. 2017, 135-144. DOI: 10.1007/978-3-319-52354-5_8.
• MIF and Pulmonary DiseaseBaker T, Lee P, Sauler M. MIF and Pulmonary Disease: MIF Family Cytokines in Innate Immunity and Homeostasis, Springer, 2017
• MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritisYoo SA, Leng L, Kim BJ, Du X, Tilstam PV, Kim KH, Kong JS, Yoon HJ, Liu A, Wang T, Song Y, Sauler M, Bernhagen J, Ritchlin CT, Lee P, Cho CS, Kim WU, Bucala R. MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2016, 113: e7917-e7926. PMID: 27872288, PMCID: PMC5150393, DOI: 10.1073/pnas.1612717113.
• D‐dopachrome tautomerase in adipose tissue inflammation and wound repairKim B, Tilstam PV, Hwang SS, Simons D, Schulte W, Leng L, Sauler M, Ganse B, Averdunk L, Kopp R, Stoppe C, Bernhagen J, Pallua N, Bucala R. D‐dopachrome tautomerase in adipose tissue inflammation and wound repair. Journal Of Cellular And Molecular Medicine 2016, 21: 35-45. PMID: 27605340, PMCID: PMC5192814, DOI: 10.1111/jcmm.12936.
• The clinical significance of the MIF homolog d-dopachrome tautomerase (MIF-2) and its circulating receptor (sCD74) in burnKim BS, Stoppe C, Grieb G, Leng L, Sauler M, Assis D, Simons D, Boecker AH, Schulte W, Piecychna M, Hager S, Bernhagen J, Pallua N, Bucala R. The clinical significance of the MIF homolog d-dopachrome tautomerase (MIF-2) and its circulating receptor (sCD74) in burn. Burns 2016, 42: 1265-1276. PMID: 27209369, PMCID: PMC5010466, DOI: 10.1016/j.burns.2016.02.005.
• Transcription factor ICBP90 regulates the MIF promoter and immune susceptibility locusYao J, Leng L, Sauler M, Fu W, Zheng J, Zhang Y, Du X, Yu X, Lee P, Bucala R. Transcription factor ICBP90 regulates the MIF promoter and immune susceptibility locus. Journal Of Clinical Investigation 2016, 126: 732-744. PMID: 26752645, PMCID: PMC4731159, DOI: 10.1172/jci81937.
• COPD: Clinical Manifestations and Management (include pulmonary rehabilitation)COPD: Clinical Manifestations and Management (include pulmonary rehabilitation). By Rennard S, Dela Cruz CS, Sauler M. Clinical Advisor Dec 20, 2016.
• Role of macrophage migration inhibitory factor in age-related lung diseaseSauler M, Bucala R, Lee PJ. Role of macrophage migration inhibitory factor in age-related lung disease. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2015, 309: l1-l10. PMID: 25957294, PMCID: PMC4491511, DOI: 10.1152/ajplung.00339.2014.
• Suppression of NLRX1 in chronic obstructive pulmonary diseaseKang MJ, Yoon CM, Kim BH, Lee CM, Zhou Y, Sauler M, Homer R, Dhamija A, Boffa D, West AP, Shadel GS, Ting JP, Tedrow JR, Kaminski N, Kim WJ, Lee CG, Oh YM, Elias JA. Suppression of NLRX1 in chronic obstructive pulmonary disease. Journal Of Clinical Investigation 2015, 125: 2458-2462. PMID: 25938787, PMCID: PMC4497738, DOI: 10.1172/jci71747.
• Oxidants in Acute and Chronic Lung DiseaseMannam P, Srivastava A, Sugunaraj JP, Lee PJ, Sauler M. Oxidants in Acute and Chronic Lung Disease. Journal Of Blood & Lymph 2014, 4: 1000128. PMID: 25705575, PMCID: PMC4335304, DOI: 10.4172/2165-7831.1000128.
• Unresolved pulmonary embolism leading to a diagnosis of pulmonary artery sarcomaGutiérrez A, Sauler M, Mitchell JM, Siegel MD, Trow TK, Bacchetta M, Fares WH. Unresolved pulmonary embolism leading to a diagnosis of pulmonary artery sarcoma. Heart & Lung 2014, 43: 574-576. PMID: 24928184, DOI: 10.1016/j.hrtlng.2014.05.006.
• Endothelial PINK1 Mediates the Protective Effects of NLRP3 Deficiency during Lethal Oxidant InjuryZhang Y, Sauler M, Shinn AS, Gong H, Haslip M, Shan P, Mannam P, Lee PJ. Endothelial PINK1 Mediates the Protective Effects of NLRP3 Deficiency during Lethal Oxidant Injury. The Journal Of Immunology 2014, 192: 5296-5304. PMID: 24778451, PMCID: PMC4047670, DOI: 10.4049/jimmunol.1400653.
• Standard Nonspecific Therapies in the Management of Pulmonary Arterial HypertensionSauler M, Fares WH, Trow TK. Standard Nonspecific Therapies in the Management of Pulmonary Arterial Hypertension. Clinics In Chest Medicine 2013, 34: 799-810. PMID: 24267305, DOI: 10.1016/j.ccm.2013.08.013.
• Lung endothelial HO‐1 targeting in vivo using lentiviral miRNA regulates apoptosis and autophagy during oxidant injuryZhang Y, Jiang G, Sauler M, Lee PJ. Lung endothelial HO‐1 targeting in vivo using lentiviral miRNA regulates apoptosis and autophagy during oxidant injury. The FASEB Journal 2013, 27: 4041-4058. PMID: 23771928, PMCID: PMC4046184, DOI: 10.1096/fj.13-231225.
• Newly Recognized Occupational and Environmental Causes of Chronic Terminal Airways and Parenchymal Lung DiseaseSauler M, Gulati M. Newly Recognized Occupational and Environmental Causes of Chronic Terminal Airways and Parenchymal Lung Disease. Clinics In Chest Medicine 2012, 33: 667-680. PMID: 23153608, PMCID: PMC3515663, DOI: 10.1016/j.ccm.2012.09.002.
• The Past, Present, and Future of Advance Directives as a Guide to End-of-Life Decision MakingSauler M, Siegel MD. The Past, Present, and Future of Advance Directives as a Guide to End-of-Life Decision Making. CHEST Journal 2012, 141: 9-10. PMID: 22215824, DOI: 10.1378/chest.11-2744.
• Pulmonary Embolism in Older PatientsMathur A, Sauler M, Pisani M. Pulmonary Embolism in Older Patients. 2011, 133-153. DOI: 10.1007/978-1-60761-727-3_7.
• Pulmonary Embolism in Older Patients38. Mathur A, Sauler M (co-first author), and Pisani M. Pulmonary Embolism in Older Patients: Aging and Lung Disease, A Clinical Guide. Humana Press, 2011.
• Reporting of Multivariable Methods in the Medical LiteratureTetrault J, Sauler M, Wells C, Concato J. Reporting of Multivariable Methods in the Medical Literature. Journal Of Investigative Medicine 2008, 56: 954. DOI: 10.231/jim.0b013e31818914ff.
• Reporting of Multivariable Methods in the Medical LiteratureTetrault JM, Sauler M, Wells CK, Concato J. Reporting of Multivariable Methods in the Medical Literature. Journal Of Investigative Medicine 2008, 56: 954. PMID: 18797413, DOI: 10.2310/jim.0b013e31818914ff.