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Emily Olfson, MD/PhD

Assistant Professor in the Child Study Center; Solnit Integrated Program, Yale Child Study Center

Research & Publications
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Selected Publications

Prevalence and gender distribution of trichotillomania: A systematic review and meta-analysisThomson HA, Farhat LC, Olfson E, Levine JLS, Bloch MH. Prevalence and gender distribution of trichotillomania: A systematic review and meta-analysis Journal Of Psychiatric Research 2022, 153: 73-81. PMID: 35802953, DOI: 10.1016/j.jpsychires.2022.06.058.
Whole‐exome DNA sequencing in childhood anxiety disorders identifies rare de novo damaging coding variantsOlfson E, Lebowitz ER, Hommel G, Pashankar N, Silverman WK, Fernandez TV. Whole‐exome DNA sequencing in childhood anxiety disorders identifies rare de novo damaging coding variants Depression And Anxiety 2022, 39: 474-484. PMID: 35312124, PMCID: PMC9246845, DOI: 10.1002/da.23251.
Pharmacological and behavioral treatment for trichotillomania: An updated systematic review with meta‐analysisFarhat LC, Olfson E, Nasir M, Levine JLS, Li F, Miguel EC, Bloch MH. Pharmacological and behavioral treatment for trichotillomania: An updated systematic review with meta‐analysis Depression And Anxiety 2020, 37: 715-727. PMID: 32390221, DOI: 10.1002/da.23028.
Measuring Treatment Response in Pediatric Trichotillomania: A Meta-Analysis of Clinical TrialsFarhat LC, Olfson E, Levine JLS, Li F, Franklin ME, Lee HJ, Lewin AB, McGuire JF, Rahman O, Storch EA, Tolin DF, Zickgraf HF, Bloch MH. Measuring Treatment Response in Pediatric Trichotillomania: A Meta-Analysis of Clinical Trials Journal Of Child And Adolescent Psychopharmacology 2019, 30: 306-315. PMID: 31794677, PMCID: PMC7476376, DOI: 10.1089/cap.2019.0103.
De Novo Damaging DNA Coding Mutations Are Associated With Obsessive-Compulsive Disorder and Overlap With Tourette’s Disorder and AutismCappi C, Oliphant ME, Péter Z, Zai G, Conceição do Rosário M, Sullivan CAW, Gupta AR, Hoffman EJ, Virdee M, Olfson E, Abdallah SB, Willsey AJ, Shavitt RG, Miguel EC, Kennedy JL, Richter MA, Fernandez TV. De Novo Damaging DNA Coding Mutations Are Associated With Obsessive-Compulsive Disorder and Overlap With Tourette’s Disorder and Autism Biological Psychiatry 2019, 87: 1035-1044. PMID: 31771860, PMCID: PMC7160031, DOI: 10.1016/j.biopsych.2019.09.029.
Identifying standardized definitions of treatment response in trichotillomania: A meta-analysisFarhat LC, Olfson E, Li F, Telang S, Bloch MH. Identifying standardized definitions of treatment response in trichotillomania: A meta-analysis Progress In Neuro-Psychopharmacology And Biological Psychiatry 2018, 89: 446-455. PMID: 30336171, DOI: 10.1016/j.pnpbp.2018.10.009.
Genes Orchestrating Brain FunctionOlfson E, Ross DA. Genes Orchestrating Brain Function Biological Psychiatry 2017, 82: e17-e19. PMID: 28693738, PMCID: PMC5712901, DOI: 10.1016/j.biopsych.2017.06.003.
CYP2A6 metabolism in the development of smoking behaviors in young adultsOlfson E, Bloom J, Bertelsen S, Budde JP, Breslau N, Brooks A, Culverhouse R, Chan G, Chen L, Chorlian D, Dick DM, Edenberg HJ, Hartz S, Hatsukami D, Hesselbrock VM, Johnson EO, Kramer JR, Kuperman S, Meyers JL, Nurnberger J, Porjesz B, Saccone NL, Schuckit MA, Stitzel J, Tischfield JA, Rice JP, Goate A, Bierut LJ. CYP2A6 metabolism in the development of smoking behaviors in young adults Addiction Biology 2016, 23: 437-447. PMID: 28032407, PMCID: PMC5491369, DOI: 10.1111/adb.12477.
The significant impact of education, poverty, and race on Internet-based research participant engagementHartz SM, Quan T, Ibiebele A, Fisher SL, Olfson E, Salyer P, Bierut LJ. The significant impact of education, poverty, and race on Internet-based research participant engagement Genetics In Medicine 2016, 19: 240-243. PMID: 27467456, PMCID: PMC5274598, DOI: 10.1038/gim.2016.91.
Implications of Personal Genomic Testing for Health Behaviors: The Case of Smoking.Olfson E, Hartz S, Carere DA, Green RC, Roberts JS, Bierut LJ. Implications of Personal Genomic Testing for Health Behaviors: The Case of Smoking. Nicotine & Tobacco Research 2016, 18: 2273-2277. PMID: 27613923, PMCID: PMC5103936, DOI: 10.1093/ntr/ntw168.
When Does Choice of Accuracy Measure Alter Imputation Accuracy Assessments?Ramnarine S, Zhang J, Chen LS, Culverhouse R, Duan W, Hancock DB, Hartz SM, Johnson EO, Olfson E, Schwantes-An TH, Saccone NL. When Does Choice of Accuracy Measure Alter Imputation Accuracy Assessments? PLOS ONE 2015, 10: e0137601. PMID: 26458263, PMCID: PMC4601794, DOI: 10.1371/journal.pone.0137601.
Identification of Medically Actionable Secondary Findings in the 1000 GenomesOlfson E, Cottrell CE, Davidson NO, Gurnett CA, Heusel JW, Stitziel NO, Chen LS, Hartz S, Nagarajan R, Saccone NL, Bierut LJ. Identification of Medically Actionable Secondary Findings in the 1000 Genomes PLOS ONE 2015, 10: e0135193. PMID: 26332594, PMCID: PMC4558085, DOI: 10.1371/journal.pone.0135193.
Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African AmericansOlfson E, Saccone NL, Johnson EO, Chen LS, Culverhouse R, Doheny K, Foltz SM, Fox L, Gogarten SM, Hartz S, Hetrick K, Laurie CC, Marosy B, Amin N, Arnett D, Barr RG, Bartz TM, Bertelsen S, Borecki IB, Brown MR, Chasman DI, van Duijn CM, Feitosa MF, Fox ER, Franceschini N, Franco OH, Grove ML, Guo X, Hofman A, Kardia SL, Morrison AC, Musani SK, Psaty BM, Rao DC, Reiner AP, Rice K, Ridker PM, Rose LM, Schick UM, Schwander K, Uitterlinden AG, Vojinovic D, Wang JC, Ware EB, Wilson G, Yao J, Zhao W, Breslau N, Hatsukami D, Stitzel JA, Rice J, Goate A, Bierut LJ. Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans Molecular Psychiatry 2015, 21: 601-607. PMID: 26239294, PMCID: PMC4740321, DOI: 10.1038/mp.2015.105.
An ADH1B Variant and Peer Drinking in Progression to Adolescent Drinking Milestones: Evidence of a Gene‐by‐Environment InteractionOlfson E, Edenberg HJ, Nurnberger J, Agrawal A, Bucholz KK, Almasy LA, Chorlian D, Dick DM, Hesselbrock VM, Kramer JR, Kuperman S, Porjesz B, Schuckit MA, Tischfield JA, Wang J, Wetherill L, Foroud TM, Rice J, Goate A, Bierut LJ. An ADH1B Variant and Peer Drinking in Progression to Adolescent Drinking Milestones: Evidence of a Gene‐by‐Environment Interaction Alcoholism Clinical And Experimental Research 2014, 38: 2541-2549. PMID: 25257461, PMCID: PMC4256939, DOI: 10.1111/acer.12524.
Return of individual genetic results in a high-risk sample: enthusiasm and positive behavioral changeHartz SM, Olfson E, Culverhouse R, Cavazos-Rehg P, Chen LS, DuBois J, Fisher S, Kaphingst K, Kaufman D, Plunk A, Ramnarine S, Solomon S, Saccone NL, Bierut LJ. Return of individual genetic results in a high-risk sample: enthusiasm and positive behavioral change Genetics In Medicine 2014, 17: 374-379. PMID: 25166427, PMCID: PMC4344933, DOI: 10.1038/gim.2014.110.
Summaries of oral sessions at the XXI World Congress of Psychiatric Genetics, Boston, Massachusetts, 17–21 October 2013Akpudo H, Aleksic B, Alkelai A, Burton C, Roa T, Chen DT, Cheng MC, Cocchi E, Davis LK, Giori IG, Hubbard LM, Merikangas A, Moily NS, Okewole A, Olfson E, Pappa I, Reitt M, Singh AB, Steinberg J, Strohmaier J, Ting TT, van Hulzen KJ, O’Shea A, DeLisi LE. Summaries of oral sessions at the XXI World Congress of Psychiatric Genetics, Boston, Massachusetts, 17–21 October 2013 Psychiatric Genetics 2014, 24: 125-150. PMID: 24912047, DOI: 10.1097/ypg.0000000000000043.
Convergence of Genome‐Wide Association and Candidate Gene Studies for AlcoholismOlfson E, Bierut LJ. Convergence of Genome‐Wide Association and Candidate Gene Studies for Alcoholism Alcoholism Clinical And Experimental Research 2012, 36: 2086-2094. PMID: 22978509, PMCID: PMC3521088, DOI: 10.1111/j.1530-0277.2012.01843.x.
Rare and Common Variants in CARD14, Encoding an Epidermal Regulator of NF-kappaB, in PsoriasisJordan CT, Cao L, Roberson ED, Duan S, Helms CA, Nair RP, Duffin KC, Stuart PE, Goldgar D, Hayashi G, Olfson EH, Feng BJ, Pullinger CR, Kane JP, Wise CA, Goldbach-Mansky R, Lowes MA, Peddle L, Chandran V, Liao W, Rahman P, Krueger GG, Gladman D, Elder JT, Menter A, Bowcock AM. Rare and Common Variants in CARD14, Encoding an Epidermal Regulator of NF-kappaB, in Psoriasis American Journal Of Human Genetics 2012, 90: 796-808. PMID: 22521419, PMCID: PMC3376540, DOI: 10.1016/j.ajhg.2012.03.013.
Analysis of insertional sites of the SIRE1 retroelement family from Glycine max using GenBank BAC-end sequences.Flasch DA, Rebman EK, Olfson EH, Nguyen KK, Geirut LE, Garland MC, Lindorfer CM, Laten HM. Analysis of insertional sites of the SIRE1 retroelement family from Glycine max using GenBank BAC-end sequences. In Silico Biology 2008, 8: 531-43. PMID: 19374136.
Accessibility and longevity of Internet citations in a clinical AIDS journal.Olfson E, Laurence J. Accessibility and longevity of Internet citations in a clinical AIDS journal. AIDS Patient Care And STDs 2005, 19: 5-8. PMID: 15665630, DOI: 10.1089/apc.2005.19.5.

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