Tyrone Cannon
Clark L. Hull Professor of Psychology and Professor of Psychiatry
Research & Publications
Biography
News
Coauthors
Selected Publications
- Genetically Informed Study Highlights Income-Independent Effect of Schizophrenia Liability on Mental and Physical HealthKouakou M, Cabrera-Mendoza B, Pathak G, Cannon T, Polimanti R. Genetically Informed Study Highlights Income-Independent Effect of Schizophrenia Liability on Mental and Physical Health. Schizophrenia Bulletin 2024, sbae093. PMID: 38848523, DOI: 10.1093/schbul/sbae093.
- The Italian adaptation of the Mini‐SIPS, a tool for early detection of individuals at clinical high risk and first episode of psychosis: A preliminary study of implementation in an Italian FEP programFerrara M, Basaldella M, Vacca F, Woods S, Walsh B, Cannon T, Srihari V, Grassi L. The Italian adaptation of the Mini‐SIPS, a tool for early detection of individuals at clinical high risk and first episode of psychosis: A preliminary study of implementation in an Italian FEP program. Early Intervention In Psychiatry 2024 PMID: 38769052, DOI: 10.1111/eip.13548.
- The Complex Latent Structure of Attenuated Psychotic Symptoms: Hierarchical and Bifactor Models of SIPS Symptoms Replicated in Two Large Samples at Clinical High Risk for PsychosisCowan H, Williams T, Mittal V, Addington J, Bearden C, Cadenhead K, Cannon T, Cornblatt B, Keshevan M, Perkins D, Mathalon D, Stone W, Woods S, Walker E. The Complex Latent Structure of Attenuated Psychotic Symptoms: Hierarchical and Bifactor Models of SIPS Symptoms Replicated in Two Large Samples at Clinical High Risk for Psychosis. Schizophrenia Bulletin 2024, sbae042. PMID: 38728417, DOI: 10.1093/schbul/sbae042.
- Information processing style and institutional trust as factors of COVID vaccine hesitancyZhao W, Russell C, Jankovsky A, Cannon T, Pittenger C, Pushkarskaya H. Information processing style and institutional trust as factors of COVID vaccine hesitancy. Scientific Reports 2024, 14: 10416. PMID: 38710827, PMCID: PMC11074285, DOI: 10.1038/s41598-024-60788-y.
- Longitudinal Trajectories of Premorbid Social and Academic Adjustment in Youth at Clinical High Risk for Psychosis: Implications for ConversionCowan H, Mittal V, Addington J, Bearden C, Cadenhead K, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Stone W, Tsuang M, Woods S, Cannon T, Walker E. Longitudinal Trajectories of Premorbid Social and Academic Adjustment in Youth at Clinical High Risk for Psychosis: Implications for Conversion. Schizophrenia Bulletin 2024, sbae050. PMID: 38706103, DOI: 10.1093/schbul/sbae050.
- Social Engagement Moderates Relations Between Hippocampal-Temporoparietal Junction Connectivity and Neighborhood Social Fragmentation in Youth at Clinical High Risk for PsychosisAberizk K, Addington J, Bearden C, Cadenhead K, Cannon T, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Stone W, Tsuang M, Woods S, Walker E, Ku B. Social Engagement Moderates Relations Between Hippocampal-Temporoparietal Junction Connectivity and Neighborhood Social Fragmentation in Youth at Clinical High Risk for Psychosis. Biological Psychiatry 2024, 95: s37-s38. DOI: 10.1016/j.biopsych.2024.02.095.
- 451. Group Iterative Multiple Model Estimation Reveals Individuals at Clinical High-Risk for Psychosis and Healthy Comparisons Self-Organize by Premorbid Adjustment According to Patterns of Temporoparietal Brain ConnectivityAberizk K, Ku B, Addington J, Bearden C, Cadenhead K, Cannon T, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Stone W, Tsuang M, Woods S, Walker E. 451. Group Iterative Multiple Model Estimation Reveals Individuals at Clinical High-Risk for Psychosis and Healthy Comparisons Self-Organize by Premorbid Adjustment According to Patterns of Temporoparietal Brain Connectivity. Biological Psychiatry 2024, 95: s284. DOI: 10.1016/j.biopsych.2024.02.950.
- 12. Reduced P300 Responses Are Associated With Altered Excitatory and Inhibitory Cell Function in High-Risk Individuals who Convert to Psychosis: Insights From the NAPLS-2 SampleRodriguez-Sanchez J, Hauke D, Friston K, Cannon T, Mathalon D, Adams R. 12. Reduced P300 Responses Are Associated With Altered Excitatory and Inhibitory Cell Function in High-Risk Individuals who Convert to Psychosis: Insights From the NAPLS-2 Sample. Biological Psychiatry 2024, 95: s79. DOI: 10.1016/j.biopsych.2024.02.190.
- Race/ethnicity and socioeconomic status as predictors of outcome following family therapy in youth at clinical high risk for psychosisRuiz‐Yu B, Le T, Weintraub M, Zinberg J, Addington J, O'Brien M, Walsh B, Friedman‐Yakoobian M, Auther A, Cornblatt, Domingues I, Cannon T, Miklowitz D, Bearden C. Race/ethnicity and socioeconomic status as predictors of outcome following family therapy in youth at clinical high risk for psychosis. Early Intervention In Psychiatry 2024 PMID: 38676463, DOI: 10.1111/eip.13541.
- Does recency of prodromal symptom onset or worsening matter for psychosis prediction?Cannon T. Does recency of prodromal symptom onset or worsening matter for psychosis prediction? Early Intervention In Psychiatry 2024, 18: 273-274. PMID: 38586971, DOI: 10.1111/eip.13459.
- The Hierarchical Taxonomy of Psychopathology in Clinical High Risk for Psychosis: Validation and ExtensionWilliams T, Williams A, Cowan H, Walker E, Cannon T, Bearden C, Keshavan M, Cornblatt B, Addington J, Woods S, Perkins D, Mathalon D, Cadenhead K, Stone W, Mittal V. The Hierarchical Taxonomy of Psychopathology in Clinical High Risk for Psychosis: Validation and Extension. Journal Of Psychopathology And Clinical Science 2024, 133: 235-244. PMID: 38546628, DOI: 10.1037/abn0000893.
- Plasma complement and coagulation proteins as prognostic factors of negative symptoms: An analysis of the NAPLS 2 and 3 studiesByrne J, Healy C, Föcking M, Heurich M, Susai S, Mongan D, Wynne K, Kodosaki E, Woods S, Cornblatt B, Stone W, Mathalon D, Bearden C, Cadenhead K, Addington J, Walker E, Cannon T, Cannon M, Jeffries C, Perkins D, Cotter D. Plasma complement and coagulation proteins as prognostic factors of negative symptoms: An analysis of the NAPLS 2 and 3 studies. Brain Behavior And Immunity 2024, 119: 188-196. PMID: 38555993, DOI: 10.1016/j.bbi.2024.03.049.
- Genetic contribution to microglial activation in schizophreniaKoskuvi M, Pörsti E, Hewitt T, Räsänen N, Wu Y, Trontti K, McQuade A, Kalyanaraman S, Ojansuu I, Vaurio O, Cannon T, Lönnqvist J, Therman S, Suvisaari J, Kaprio J, Blurton-Jones M, Hovatta I, Lähteenvuo M, Rolova T, Lehtonen Š, Tiihonen J, Koistinaho J. Genetic contribution to microglial activation in schizophrenia. Molecular Psychiatry 2024, 1-12. PMID: 38519640, DOI: 10.1038/s41380-024-02529-1.
- Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ): Rationale and Study Design of the Largest Global Prospective Cohort Study of Clinical High Risk for PsychosisWannan C, Nelson B, Addington J, Allott K, Anticevic A, Arango C, Baker J, Bearden C, Billah T, Bouix S, Broome M, Buccilli K, Cadenhead K, Calkins M, Cannon T, Cecci G, Chen E, Cho K, Choi J, Clark S, Coleman M, Conus P, Corcoran C, Cornblatt B, Diaz-Caneja C, Dwyer D, Ebdrup B, Ellman L, Fusar-Poli P, Galindo L, Gaspar P, Gerber C, Glenthøj L, Glynn R, Harms M, Horton L, Kahn R, Kambeitz J, Kambeitz-Ilankovic L, Kane J, Kapur T, Keshavan M, Kim S, Koutsouleris N, Kubicki M, Kwon J, Langbein K, Lewandowski K, Light G, Mamah D, Marcy P, Mathalon D, McGorry P, Mittal V, Nordentoft M, Nunez A, Pasternak O, Pearlson G, Perez J, Perkins D, Powers A, Roalf D, Sabb F, Schiffman J, Shah J, Smesny S, Spark J, Stone W, Strauss G, Tamayo Z, Torous J, Upthegrove R, Vangel M, Verma S, Wang J, Rossum I, Wolf D, Wolff P, Wood S, Yung A, Agurto C, Alvarez-Jimenez M, Amminger P, Armando M, Asgari-Targhi A, Cahill J, Carrión R, Castro E, Cetin-Karayumak S, Chakravarty M, Cho Y, Cotter D, D’Alfonso S, Ennis M, Fadnavis S, Fonteneau C, Gao C, Gupta T, Gur R, Gur R, Hamilton H, Hoftman G, Jacobs G, Jarcho J, Ji J, Kohler C, Lalousis P, Lavoie S, Lepage M, Liebenthal E, Mervis J, Murty V, Nicholas S, Ning L, Penzel N, Poldrack R, Polosecki P, Pratt D, Rabin R, Eichi H, Rathi Y, Reichenberg A, Reinen J, Rogers J, Ruiz-Yu B, Scott I, Seitz-Holland J, Srihari V, Srivastava A, Thompson A, Turetsky B, Walsh B, Whitford T, Wigman J, Yao B, Yuen H, Ahmed U, Byun A, Chung Y, Do K, Hendricks L, Huynh K, Jeffries C, Lane E, Langholm C, Lin E, Mantua V, Santorelli G, Ruparel K, Zoupou E, Adasme T, Addamo L, Adery L, Ali M, Auther A, Aversa S, Baek S, Bates K, Bathery A, Bayer J, Beedham R, Bilgrami Z, Birch S, Bonoldi I, Borders O, Borgatti R, Brown L, Bruna A, Carrington H, Castillo-Passi R, Chen J, Cheng N, Ching A, Clifford C, Colton B, Contreras P, Corral S, Damiani S, Done M, Estradé A, Etuka B, Formica M, Furlan R, Geljic M, Germano C, Getachew R, Goncalves M, Haidar A, Hartmann J, Jo A, John O, Kerins S, Kerr M, Kesselring I, Kim H, Kim N, Kinney K, Krcmar M, Kotler E, Lafanechere M, Lee C, Llerena J, Markiewicz C, Matnejl P, Maturana A, Mavambu A, Mayol-Troncoso R, McDonnell A, McGowan A, McLaughlin D, McIlhenny R, McQueen B, Mebrahtu Y, Mensi M, Hui C, Suen Y, Wong S, Morrell N, Omar M, Partridge A, Phassouliotis C, Pichiecchio A, Politi P, Porter C, Provenzani U, Prunier N, Raj J, Ray S, Rayner V, Reyes M, Reynolds K, Rush S, Salinas C, Shetty J, Snowball C, Tod S, Turra-Fariña G, Valle D, Veale S, Whitson S, Wickham A, Youn S, Zamorano F, Zavaglia E, Zinberg J, Woods S, Shenton M. Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ): Rationale and Study Design of the Largest Global Prospective Cohort Study of Clinical High Risk for Psychosis. Schizophrenia Bulletin 2024, 50: 496-512. PMID: 38451304, PMCID: PMC11059785, DOI: 10.1093/schbul/sbae011.
- Moral learning and positive schizotypy: Social cognitive mechanisms in psychosis- pronenessZhao W, Cannon T. Moral learning and positive schizotypy: Social cognitive mechanisms in psychosis- proneness. Schizophrenia Research 2024, 266: 156-164. PMID: 38402656, DOI: 10.1016/j.schres.2024.02.023.
- Proteomic Biomarkers for the Prediction of Transition to Psychosis in Individuals at Clinical High Risk: A Multi-cohort Model Development StudyByrne J, Healy C, Föcking M, Susai S, Mongan D, Wynne K, Kodosaki E, Heurich M, de Haan L, Hickie I, Smesny S, Thompson A, Markulev C, Young A, Schäfer M, Riecher-Rössler A, Mossaheb N, Berger G, Schlögelhofer M, Nordentoft M, Chen E, Verma S, Nieman D, Woods S, Cornblatt B, Stone W, Mathalon D, Bearden C, Cadenhead K, Addington J, Walker E, Cannon T, Cannon M, McGorry P, Amminger P, Cagney G, Nelson B, Jeffries C, Perkins D, Cotter D. Proteomic Biomarkers for the Prediction of Transition to Psychosis in Individuals at Clinical High Risk: A Multi-cohort Model Development Study. Schizophrenia Bulletin 2024, 50: 579-588. PMID: 38243809, PMCID: PMC11059811, DOI: 10.1093/schbul/sbad184.
- Differential expression of haptoglobin in individuals at clinical high risk of psychosis and its association with global functioning and clinical symptomsHealy C, Byrne J, Raj Suasi S, Föcking M, Mongan D, Kodosaki E, Heurich M, Cagney G, Wynne K, Bearden C, Woods S, Cornblatt B, Mathalon D, Stone W, Cannon T, Addington J, Cadenhead K, Perkins D, Jeffries C, Cotter D. Differential expression of haptoglobin in individuals at clinical high risk of psychosis and its association with global functioning and clinical symptoms. Brain Behavior And Immunity 2024, 117: 175-180. PMID: 38219978, DOI: 10.1016/j.bbi.2023.12.018.
- Psychosis superspectrum I: Nosology, etiology, and lifespan developmentJonas K, Cannon T, Docherty A, Dwyer D, Gur R, Gur R, Nelson B, Reininghaus U, Kotov R. Psychosis superspectrum I: Nosology, etiology, and lifespan development. Molecular Psychiatry 2024, 29: 1005-1019. PMID: 38200290, DOI: 10.1038/s41380-023-02388-2.
- Notice of Retraction: Worthington MA et al. Dynamic Prediction of Outcomes for Youth at Clinical High Risk for Psychosis: A Joint Modeling Approach. JAMA Psychiatry. 2023;80(10):1017-1025.Cannon T, Worthington M, Addington J, Bearden C, Cadenhead K, Cornblatt B, Keshavan M, Lympus C, Mathalon D, Perkins D, Stone W, Walker E, Woods S, Zhao Y. Notice of Retraction: Worthington MA et al. Dynamic Prediction of Outcomes for Youth at Clinical High Risk for Psychosis: A Joint Modeling Approach. JAMA Psychiatry. 2023;80(10):1017-1025. JAMA Psychiatry 2024, 81: 109-110. PMID: 37917049, DOI: 10.1001/jamapsychiatry.2023.4732.
- Linking enlarged choroid plexus with plasma analyte and structural phenotypes in clinical high risk for psychosis: A multisite neuroimaging studyBannai D, Reuter M, Hegde R, Hoang D, Adhan I, Gandu S, Pong S, Raymond N, Zeng V, Chung Y, He G, Sun D, van Erp T, Addington J, Bearden C, Cadenhead K, Cornblatt B, Mathalon D, McGlashan T, Jeffries C, Stone W, Tsuang M, Walker E, Woods S, Cannon T, Perkins D, Keshavan M, Lizano P. Linking enlarged choroid plexus with plasma analyte and structural phenotypes in clinical high risk for psychosis: A multisite neuroimaging study. Brain Behavior And Immunity 2023, 117: 70-79. PMID: 38169244, PMCID: PMC10932816, DOI: 10.1016/j.bbi.2023.12.021.
- Borderline personality disorder features are associated with inflexible social interpretationsDuda J, Fineberg S, Deng W, Ma Y, Everaert J, Cannon T, Joormann J. Borderline personality disorder features are associated with inflexible social interpretations. Journal Of Affective Disorders 2023, 348: 78-87. PMID: 38110156, DOI: 10.1016/j.jad.2023.12.036.
- Relations of Lifetime Perceived Stress and Basal Cortisol with Hippocampal Volume among Healthy Adolescents and those at Clinical High-Risk for Psychosis: A Structural Equation Modeling ApproachAberizk K, Addington J, Bearden C, Cadenhead K, Cannon T, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Stone W, Tsuang M, Woods S, Walker E, Ku B. Relations of Lifetime Perceived Stress and Basal Cortisol with Hippocampal Volume among Healthy Adolescents and those at Clinical High-Risk for Psychosis: A Structural Equation Modeling Approach. Biological Psychiatry 2023 PMID: 38092185, PMCID: PMC11166888, DOI: 10.1016/j.biopsych.2023.11.027.
- Conspiracy mentality, subclinical paranoia, and political conservatism are associated with perceived status threatKoller W, Thompson H, Cannon T. Conspiracy mentality, subclinical paranoia, and political conservatism are associated with perceived status threat. PLOS ONE 2023, 18: e0293930. PMID: 37992025, PMCID: PMC10664880, DOI: 10.1371/journal.pone.0293930.
- On the clinical utility of individualized prediction models for psychosis in at risk youthCannon T. On the clinical utility of individualized prediction models for psychosis in at risk youth. Biological Psychiatry 2023 PMID: 37949345, DOI: 10.1016/j.biopsych.2023.11.003.
- 73 Identification of 24-Month Cognitive Trajectories Among Clinical High Risk for Psychosis (CHR-P) Using Latent Class Mixture ModelingGuest R, Addington J, Bearden C, Cadenhead K, Cornblatt B, Mathalon D, Perkins D, Tsuang M, Woods S, Cannon T, Keshavan M, Stone W, Walker E. 73 Identification of 24-Month Cognitive Trajectories Among Clinical High Risk for Psychosis (CHR-P) Using Latent Class Mixture Modeling. Journal Of The International Neuropsychological Society 2023, 29: 857-858. DOI: 10.1017/s1355617723010597.
- Predicting Conversion to Psychosis Using Machine Learning: Are We There Yet?Cannon T. Predicting Conversion to Psychosis Using Machine Learning: Are We There Yet? American Journal Of Psychiatry 2023, 180: 789-791. PMID: 37908096, DOI: 10.1176/appi.ajp.20230711.
- Interactions of genetic predisposition and intrauterine events in the etiology of schizophreniaEllman L, Cannon T. Interactions of genetic predisposition and intrauterine events in the etiology of schizophrenia. 2006, 19-40. DOI: 10.1093/oso/9780198510840.003.0002.
- Automated analysis of structural MRI dataThompson P, Rapoport J, Cannon T, Toga A. Automated analysis of structural MRI data. 2004, 119-166. DOI: 10.1093/oso/9780198525967.003.0006.