As neurodegenerative diseases and cancers pose a huge challenge to our society, novel and creative approaches are needed to illuminate their pathogenesis, detect the diseases at early stages to allow for more effective interventions, and monitor therapeutic effects. We are developing novel PET imaging approaches that directly measure biochemical or phenotypic changes in living subjects, through the integration of medicinal chemistry, radiochemistry, quantitatvie PET imaging, and pharmacology.
PET imaging; Brain imaging; Cancer diagnosis and prognosis; Biomarker and drug discovery and development
Alzheimer Disease; Chemistry, Pharmaceutical; Pharmacokinetics; Pharmacology; Biomarkers; Neurodegenerative Diseases; Positron-Emission Tomography; Drug Discovery; Drug Development
Aging; Biomarkers