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Martin Schwartz, PhD

Robert W. Berliner Professor of Medicine (Cardiology) and Professor of Biomedical Engineering and of Cell Biology

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Martin Schwartz, PhD



Martin Schwartz earned a BA in chemistry from New College in Sarasota FL and a PhD in physical chemistry from Stanford, where he worked in Harden McConnell’s lab on biophysics of phospholipid membranes.He then did postdoctoral research in biology at MIT in the laboratory of Richard Hynes where he studied interactions of fibronectin with cells and other proteins. He was on the faculty at Harvard Medical School, Scripps Research Institute and the University of Virginia prior to moving to Yale in 2011. Starting in the 1980’s, his lab was among the first to report that integrin mediated adhesion could regulate signaling pathways in cells;that integrin-mediated adhesion promotes cell survival, that integrins synergize with growth factor receptors to activate growth signaling pathways and that integrins regulate Rho family GTPases. His lab has also elucidated mechanotransduction pathways by which endothelial cells respond to fluid shear stress to activate inflammatory pathways linked to atherosclerosis. His current research program combines studies using biophysical, cellular and animal approaches to important questions about integrin signaling, mechanotransduction and disease in the vascular system.

Education & Training

  • Postdoctoral fellow
    MIT (1982)
  • PhD
    Stanford University (1979)
  • BA
    New College of the University South Florida (1975)

Honors & Recognition

AwardAwarding OrganizationDate
Greenblatt Distinguished LectureMedical College of Georgia2021
Bolie LectureUniversity of Colorado2019
Fellow of the American Society for Cell BiologyAmerican Society for Cell Biology2017
Joseph Calandra LectureNorthwestern University2017
Fellow of the American Association for Advancement of ScienceAmerican Association for Advancement of Science2016
Harold F. Dvorak Plenary LectureHarvard Medical School2013
Andrew P. Somlyo Honorary LecturePennsylvania Muscle Institute, University of Pennsylvania2013
Chair, Signaling by Cell Adhesion Receptors Gordon Research Conference2012
Robert W. Berliner Professor of MedicineYale School of Medicine2012
Chair, Vascular Cell BiologyGordon Research Conference2011
Vice Chair, Signaling by Cell Adhesion Receptors Gordon Research Conference2010
Hayashi Lecturer, Woods Hole MBL Physiology CourseMarine Biology Laboratory2009
Vice Chair, Vascular Cell BiologyGordon Research Conference2009
James O. Davis LectureshipUniversity of Missouri2009

Professional Service

NAVBO workshop on Biology of Signaling in the Cardiovascular SystemChair2015
Biological Sciences Advisory CommitteeMember2014 - 2016
NAVBO workshop on Biology of Signaling in the Cardiovascular SystemChair2013
Gordon Research Conference on Signaling by Cell Adhesion ReceptorsChair2012
American Association for Advancement of ScienceMember2012 - Present
Gordon Research Conference on Vascular Cell BiologyChair2011
Frontiers in Cell Migration and MechanotransductionCo-Chair2011
Nature, Science, Cell, Developmental Cell, PNAS, Nat Cell Biol, Curr Biol, Circ Res.Reviewer2011 - Present
Vascular Biology and Therapeutics ProgramCommittee Member2011
Mechanotransduction in Physiology and DiseaseAlpha Yap, Co- Chair Chris Chen, Co- Chair2009
ICIMember ICI study section2008 - 2011
NAVBOMember NAVBO Council2008 - 2010
Journal of Cell ScienceEditorial Board Member2006 - Present
Biochemical Journal (2006-2008)Associate Editor2006 - 2015
Journal of Cell BiologyAssociate Editor2001 - Present
Cell Communication and AdhesionEditorial Board Member1998 - 2011
Keystone Conference on Signaling by Integrins and Growth Factor ReceptorsLewis Cantley, co-chair1998
North American Vascular Biology Organization (NAVBO)Member1998 - Present
Matrix BiologyEditorial Board Member1997 - 2012
Molecular Biology of the CellAssociate Editor1996 - 2008
Keystone Conference on Integrins and Signaling Events in Cell Biology and DiseaseChair, David Cheresh1996
CDF4Member CDF4 study section1996 - 2000
American Heart AssociationMember vascular wall study section1993 - 1996
American Society for Cell BiologyMember1991 - Present

Departments & Organizations