- May 09, 2023
Getting it Right (Academic Track): Insights from Brian Coon
- July 21, 2022
Understanding how mechanical forces contribute to disease: Dr. Nicolas Baeyens
- July 19, 2022
Yale study decodes a signaling network that mediates vascular resilience
- November 23, 2021
Yale Study Identifies How Blood Flow Determines Artery Diameter
Welcome to the Schwartz Lab!
How cells coordinate to form mechanically stable, functional three dimensional tissues and organisms is arguably the most interesting and important problem in 21st century biological sciences. It underlies not just normal development and physiology but also cancer and heart disease, the major killers in developed nations. Our lab studies two critical and related aspects of these problems. They are: integrin signaling, or how cells respond to extracellular matrix; and mechanotransduction, or how cells respond to mechanical forces. We study both fundamental aspects of these processes and their roles in the vascular system, particularly atherosclerosis and other vascular diseases. More broadly, we aim to relate our basic discoveries in cell biology to human disease its treatment. Thus, as befits a basic scientist in the Yale Department of Medicine, our research program brings together tools and approaches from cell biology, biophysics and bioengineering with developmental systems and models of human disease.