Biological systems operate away from equilibrium but the applications of non-equilibrium dynamics in our current understanding of biology remain limited. The lab of Min Wu is fascinated by cortical oscillations and travelling waves that are regulated by interacting networks of phosphoinositide-metabolizing enzymes. The laboratory is currently investigating the mechanisms of these single cell pattern formation by high-resolution quantitative imaging, optogenetics and genome-editing. We aim to employ these spatial-temporal patterns as a conceptual framework to dissect fundamental cellular processes of cell growth, cell division, and cell size control.
Cell size and growth
Organelle Biogenesis; Endocytosis; Growth; Homeostasis; Nonlinear Dynamics; Nanotechnology; Cell Shape; Wavelet Analysis; Phosphoinositide Phosphatases