Stephanie Thorn, MSc, PhD

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Assistant Professor of Medicine (Cardiovascular Medicine)

Appointments

Cardiovascular Medicine

Primary

Comparative Medicine

Secondary

Titles

Associate Director, Yale Translational Research Imaging Center (Y-TRIC)

Contact Info

203.737.5917

Yale School of Medicine

PO Box 208017, DANA 3

New Haven, CT 06520-8017

United States

About

Titles

Assistant Professor of Medicine (Cardiovascular Medicine)

Associate Director, Yale Translational Research Imaging Center (Y-TRIC)

Biography

Dr Stephanie L. Thorn, MSc, PhD is a Assistant Professor in the Section of Cardiovascular Medicine, Department of Internal Medicine. Dr Thorn received her PhD at the University of Ottawa Heart Institute in Cellular and Molecular Medicine. She is currently the Associate Director of the Yale Translational Research Imaging Center (YTRIC). Her research interests are centered on cardiovascular imaging, using PET, SPECT and CT to develop new approaches in the interrogation of molecular pathways, quantification of blood flow and alterations myocardial function. Dr Thorn specifically pursues translational research in ischemia-reperfusion remodeling, myocardial infarction and right ventricular heart failure.

Appointments

Cardiovascular Medicine
Assistant Professor
Primary
Cardiovascular Medicine
Comparative Medicine
Research Scientist
Secondary
Comparative Medicine

Education & Training

PhD: University of Ottawa, Cellular and Molecular Medicine (2013)

MSc: University of Guelph, Human Biology and Nutritional Sciences (2003)

BSc (Hon): University of Guelph, Human Kinetics (2001)

YTRIC

Research

Overview

Medical Subject Headings (MeSH)

Computed Tomography Angiography; Diseases; Heart Failure; Heart Failure, Diastolic; Hypertrophy, Right Ventricular; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Positron Emission Tomography Computed Tomography; Radionuclide Imaging; Single Photon Emission Computed Tomography Computed Tomography

Research at a Glance

Yale Co-Authors

Frequent collaborators of Stephanie Thorn's published research.

Albert Sinusas, MD
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View 15 Common Publications
Chi Liu, PhD
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View 9 Common Publications
Edward J Miller, MD, PhD
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View 5 Common Publications
Yi-Hwa Liu, PhD
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View 5 Common Publications
Alaa Alashi, MD, MHS
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View 4 Common Publications
Attila Feher, MD, PhD
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View 4 Common Publications

Myocardial Infarction
6 YSM Researchers
View 9 Related Publications
Single Photon Emission Computed Tomography Computed Tomography
4 YSM Researchers
View 3 Related Publications
Heart Failure
14 YSM Researchers
View 2 Related Publications
Positron Emission Tomography Computed Tomography
6 YSM Researchers
View 2 Related Publications
Radionuclide Imaging
3 YSM Researchers
View 2 Related Publications
Myocardial Ischemia
4 YSM Researchers
View Related Publication

Publications

2024

Development Of Ct Quantitative Tools To Assess Collateral Formation In Rabbit Model Of Hind Limb Ischemia: Implications For Evaluation Of Vascular Reserve.
Vermillion B, Jang S, Alashi A, Burns R, Guerrera N, Depino A, Martins S, Papademetris X, Zeiss C, Guo L, Liu C, Thorn S, Sinusas A. Development Of Ct Quantitative Tools To Assess Collateral Formation In Rabbit Model Of Hind Limb Ischemia: Implications For Evaluation Of Vascular Reserve. Journal Of Cardiovascular Computed Tomography 2024, 18: s50-s51. DOI: 10.1016/j.jcct.2024.05.117.
Peer-Reviewed Original Research
Non-invasive Estimation Of Right Ventricle-Pulmonary Artery Coupling Using Multiphase Cardiac Computed Tomography Angiography In Pig Model Of Acute Respiratory Distress Syndrome
Jang S, Thorn S, Vermillion B, Alashi A, Zohora F, Lee S, Ahn S, Burns R, Dela Cruz C, Zeiss C, Spinale F, Heerdt P, Sinusas A. Non-invasive Estimation Of Right Ventricle-Pulmonary Artery Coupling Using Multiphase Cardiac Computed Tomography Angiography In Pig Model Of Acute Respiratory Distress Syndrome. Journal Of Cardiovascular Computed Tomography 2024, 18: s46. DOI: 10.1016/j.jcct.2024.05.106.
Peer-Reviewed Original Research
Concepts
Early Transient CT Enhancement Post Myocardial Infarction Is Associated With Technetium-99m Pyrophosphate Uptake And Calcium Deposition
Zohora F, Lee S, Lin A, Jang S, Vermillion B, Burns R, Callegari S, DePino A, Guerrera N, Thorn S, Sinusas A. Early Transient CT Enhancement Post Myocardial Infarction Is Associated With Technetium-99m Pyrophosphate Uptake And Calcium Deposition. Journal Of Cardiovascular Computed Tomography 2024, 18: s25-s26. DOI: 10.1016/j.jcct.2024.05.058.
Peer-Reviewed Original Research
Coordinate-Independent 3-D Ultrasound Principal Stretch and Direction Imaging
Jeng G, Chen P, Hsieh M, Liu Z, Langdon J, Ahn S, Staib L, Stendahl J, Thorn S, Sinusas A, Duncan J, O'Donnell M. Coordinate-Independent 3-D Ultrasound Principal Stretch and Direction Imaging. IEEE Transactions On Biomedical Engineering 2024, PP: 1-12. PMID: 38941195, DOI: 10.1109/tbme.2024.3420220.
Peer-Reviewed Original Research
Concepts
Comparative study of functional and structural muscle changes in peripheral artery disease: rubidium-82 positron emission tomography and histological correlation
Alashi A, Vermillion B, Callegari S, Burns R, Guo L, Moulton E, Guerrera N, Depino A, Papademetris X, Zeiss C, Thorn S, Liu C, Sinusas A. Comparative study of functional and structural muscle changes in peripheral artery disease: rubidium-82 positron emission tomography and histological correlation. European Heart Journal - Cardiovascular Imaging 2024, 25: jeae142.087. DOI: 10.1093/ehjci/jeae142.087.
Peer-Reviewed Original Research
Concepts
Links Between Obstructive Sleep Apnea and Myocardial Blood Flow Changes Impacting Adverse Cardiovascular Disease-related Outcomes
Aneni E, Sinusas A, Emokpae M, Thorn S, Yaggi H, Miller E. Links Between Obstructive Sleep Apnea and Myocardial Blood Flow Changes Impacting Adverse Cardiovascular Disease-related Outcomes. Current Cardiology Reports 2024, 26: 723-734. PMID: 38806976, DOI: 10.1007/s11886-024-02072-z.
Peer-Reviewed Original Research
Concepts
Multi-Task Learning for Motion Analysis and Segmentation in 3D Echocardiography
Ta K, Ahn S, Thorn S, Stendahl J, Zhang X, Langdon J, Staib L, Sinusas A, Duncan J. Multi-Task Learning for Motion Analysis and Segmentation in 3D Echocardiography. IEEE Transactions On Medical Imaging 2024, 43: 2010-2020. PMID: 38231820, DOI: 10.1109/tmi.2024.3355383.
Peer-Reviewed Original Research
Concepts
MULTIMODALITY IMAGING GUIDED INTRAMYOCARDIAL DELIVERY OF IMAGEABLE HYDROGEL POST MYOCARDIAL INFARCTION IMPROVES STRAIN ASSOCIATED WITH INTEGRIN ACTIVATION
Melvinsdottir I, Midgett D, Lee S, Chen K, Avendano R, Ahn S, Thorn S, Uman S, Sinusas A. MULTIMODALITY IMAGING GUIDED INTRAMYOCARDIAL DELIVERY OF IMAGEABLE HYDROGEL POST MYOCARDIAL INFARCTION IMPROVES STRAIN ASSOCIATED WITH INTEGRIN ACTIVATION. Journal Of The American College Of Cardiology 2024, 83: 1399. DOI: 10.1016/s0735-1097(24)03389-8.
Peer-Reviewed Original Research
ASSESSING VASCULAR FLOW IN ACUTE AND CHRONIC RABBIT MODELS OF HINDLIMB ISCHEMIA USING HIGH-RESOLUTION 2D ANGIOGRAPHY: IMPLICATIONS FOR PET FLOW QUANTIFICATION
Callegari S, Vermillion B, Alashi A, Burns R, Jang S, Guerrera N, Guo L, Depino A, Zohora F, Smolderen K, Hurtado C, Liu C, Thorn S, Sinusas A. ASSESSING VASCULAR FLOW IN ACUTE AND CHRONIC RABBIT MODELS OF HINDLIMB ISCHEMIA USING HIGH-RESOLUTION 2D ANGIOGRAPHY: IMPLICATIONS FOR PET FLOW QUANTIFICATION. Journal Of The American College Of Cardiology 2024, 83: 2251. DOI: 10.1016/s0735-1097(24)04241-4.
Peer-Reviewed Original Research

2023

The development of a novel endovascular grasper for challenging inferior vena cava filter retrieval
Ochoa Chaar C, Kostiuk V, Rodriguez P, Kim T, Rathbone D, Ghandour L, Burns R, Thorn S, Sinusas A, Guzman R, Dardik A. The development of a novel endovascular grasper for challenging inferior vena cava filter retrieval. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2023, 12: 101731. PMID: 38081514, DOI: 10.1016/j.jvsv.2023.101731.
Peer-Reviewed Original Research

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Academic Achievements and Community Involvement

activity
Hotspot Imaging in Cardiovascular Disease: Methodology of Image Acquisition and Tracer Quantification
Oral PresentationSociety of Nuclear Medicine and Molecular Imaging Annual Meeting
Details

Links & Media

Media

Right Ventricle Heart Failure
Contrast CT images of a normal myocardium and one with right ventricle heart failure.
Cardiac Ischemia-Reperfusion
Using non-invasive SPECT/CT hybrid imaging, the reduced perfusion area can be quantified. At 3-days post-ischemia, the same area shows an increase in the radiotracer uptake of the matrix metalloproteinase agent, Tc-99m RP805. This tracer is an index of cardiac remodeling.

News

April 01, 2024
Yale Faculty Present Groundbreaking Clinical Research at the 2024 American College of Cardiology Scientific Sessions
Read more
March 18, 2024
Meet Yale Internal Medicine: Stephanie Thorn, MSc, PhD
Read more
January 16, 2024
Yale's Cardiac Imaging Center Revolutionizes Translational Research
Read more
July 12, 2023
Image-guided Therapy Improves Cardiac Function Post-MI (Discoveries & Impact July 2023)
Read more

See All News

Get In Touch

Contacts

Academic Office Number

203.737.5917

Lab Number

203.785.5005

Mailing Address

Yale School of Medicine

PO Box 208017, DANA 3

New Haven, CT 06520-8017

United States

Appointments

Titles

Contact Info

Titles

Biography

Appointments

Cardiovascular Medicine

Comparative Medicine

Other Departments & Organizations

Education & Training

Overview

Medical Subject Headings (MeSH)

Research at a Glance

Yale Co-Authors

Albert Sinusas, MD

Chi Liu, PhD

Edward J Miller, MD, PhD

Yi-Hwa Liu, PhD

Alaa Alashi, MD, MHS

Attila Feher, MD, PhD

Publications

2024

2023

Hotspot Imaging in Cardiovascular Disease: Methodology of Image Acquisition and Tracer Quantification

Media

News

Yale Faculty Present Groundbreaking Clinical Research at the 2024 American College of Cardiology Scientific Sessions

Meet Yale Internal Medicine: Stephanie Thorn, MSc, PhD

Yale's Cardiac Imaging Center Revolutionizes Translational Research

Image-guided Therapy Improves Cardiac Function Post-MI (Discoveries & Impact July 2023)

Contacts