Yi-Hwa Liu, PhD

• Adriana Dana Oprea
• Albert Sinusas
• Attila Feher
• Chi Liu
• Edward J Miller
• Evangelos K. Oikonomou
• Forrester Lee
• Frans Wackers
• Inga Melvinsdottir
• James Dziura
• Jennifer Mattera
• John Onofrey
• John Stendahl
• Kim Germaine Emiel Smolderen
• MingDe Lin
• Monique Hinchcliff
• Nicha Dvornek
• Ricardo Avendaño
• Stephanie Thorn

Cardiology; Nuclear Medicine; Ventricular Function, Left; Myocardial Perfusion Imaging

• Comparison of the prognostic value between quantification and visual estimation of coronary calcification from attenuation CT in patients undergoing SPECT myocardial perfusion imagingFeher A, Pieszko K, Shanbhag A, Lemley M, Miller R, Huang C, Miras L, Liu Y, Gerber J, Sinusas A, Miller E, Slomka P. Comparison of the prognostic value between quantification and visual estimation of coronary calcification from attenuation CT in patients undergoing SPECT myocardial perfusion imaging. The International Journal Of Cardiovascular Imaging 2023, 40: 185-193. PMID: 37845406, DOI: 10.1007/s10554-023-02980-1.
• TAI-GAN: Temporally and Anatomically Informed GAN for Early-to-Late Frame Conversion in Dynamic Cardiac PET Motion CorrectionGuo X, Shi L, Chen X, Zhou B, Liu Q, Xie H, Liu Y, Palyo R, Miller E, Sinusas A, Spottiswoode B, Liu C, Dvornek N. TAI-GAN: Temporally and Anatomically Informed GAN for Early-to-Late Frame Conversion in Dynamic Cardiac PET Motion Correction. 2023, 14288: 64-74. PMID: 38464964, PMCID: PMC10923183, DOI: 10.1007/978-3-031-44689-4_7.
• Transformer-Based Dual-Domain Network for Few-View Dedicated Cardiac SPECT Image ReconstructionsXie H, Zhou B, Chen X, Guo X, Thorn S, Liu Y, Wang G, Sinusas A, Liu C. Transformer-Based Dual-Domain Network for Few-View Dedicated Cardiac SPECT Image Reconstructions. 2023, 14229: 163-172. DOI: 10.1007/978-3-031-43999-5_16.
• Correction to: Integration of coronary artery calcium scoring from CT attenuation scans by machine learning improves prediction of adverse cardiovascular events in patients undergoing SPECT/CT myocardial perfusion imagingFeher A, Pieszko K, Miller R, Lemley M, Shanbhag A, Huang C, Miras L, Liu Y, Sinusas A, Miller E, Slomka P. Correction to: Integration of coronary artery calcium scoring from CT attenuation scans by machine learning improves prediction of adverse cardiovascular events in patients undergoing SPECT/CT myocardial perfusion imaging. Journal Of Nuclear Cardiology 2023, 30: 860-863. PMID: 36598750, DOI: 10.1007/s12350-022-03196-x.
• ASSOCIATION OF RB-82 PET DERIVED REGIONAL MYOCARDIAL BLOOD FLOW TO SEVERITY OF ANGIOGRAPHIC CORONARY ARTERY STENOSIS IN PATIENTS PRESENTING WITH ACUTE CHEST PAINHu J, Trejo-Paredes C, Shah S, Liu Y, Smolderen K, Hurtado C, Sinusas A, Miller E, Kattan C. ASSOCIATION OF RB-82 PET DERIVED REGIONAL MYOCARDIAL BLOOD FLOW TO SEVERITY OF ANGIOGRAPHIC CORONARY ARTERY STENOSIS IN PATIENTS PRESENTING WITH ACUTE CHEST PAIN. Journal Of The American College Of Cardiology 2023, 81: 1409. DOI: 10.1016/s0735-1097(23)01853-3.
• IN PATIENTS UNDERGOING NUCLEAR MYOCARDIAL PERFUSION IMAGING, RHEUMATOID ARTHRITIS IS ASSOCIATED WITH INCREASED RISK OF ADVERSE CARDIOVASCULAR EVENTS INDEPENDENT OF MYOCARDIAL ISCHEMIAPires J, Oikonomou E, Agarwal R, Liu Y, miller E, Sinusas A, Feher A. IN PATIENTS UNDERGOING NUCLEAR MYOCARDIAL PERFUSION IMAGING, RHEUMATOID ARTHRITIS IS ASSOCIATED WITH INCREASED RISK OF ADVERSE CARDIOVASCULAR EVENTS INDEPENDENT OF MYOCARDIAL ISCHEMIA. Journal Of The American College Of Cardiology 2023, 81: 1467. DOI: 10.1016/s0735-1097(23)01911-3.
• CORONARY ARTERY CALCIFICATIONS ARE A BETTER PREDICTOR OF CARDIOVASCULAR OUTCOMES THAN ISCHEMIC ECG CHANGES IN PATIENTS WITH NORMAL PERFUSION ON EXERCISE SPECTShi T, Kokkinidis D, Agarwal R, Liu Y, Sinusas A, Miller E, Feher A. CORONARY ARTERY CALCIFICATIONS ARE A BETTER PREDICTOR OF CARDIOVASCULAR OUTCOMES THAN ISCHEMIC ECG CHANGES IN PATIENTS WITH NORMAL PERFUSION ON EXERCISE SPECT. Journal Of The American College Of Cardiology 2023, 81: 1498. DOI: 10.1016/s0735-1097(23)01942-3.
• RB-82 PET DERIVED REGIONAL MYOCARDIAL BLOOD FLOW IS ASSOCIATED WITH ALL-CAUSE MORTALITY IN PATIENTS PRESENTING WITH ACUTE CHEST PAINTrejo-Paredes C, Hu J, Shah S, Liu Y, Smolderen K, Hurtado C, Sinusas A, Miller E. RB-82 PET DERIVED REGIONAL MYOCARDIAL BLOOD FLOW IS ASSOCIATED WITH ALL-CAUSE MORTALITY IN PATIENTS PRESENTING WITH ACUTE CHEST PAIN. Journal Of The American College Of Cardiology 2023, 81: 1502. DOI: 10.1016/s0735-1097(23)01946-0.
• Integration of coronary artery calcium scoring from CT attenuation scans by machine learning improves prediction of adverse cardiovascular events in patients undergoing SPECT/CT myocardial perfusion imagingFeher A, Pieszko K, Miller R, Lemley M, Shanbhag A, Huang C, Miras L, Liu YH, Sinusas AJ, Miller EJ, Slomka PJ. Integration of coronary artery calcium scoring from CT attenuation scans by machine learning improves prediction of adverse cardiovascular events in patients undergoing SPECT/CT myocardial perfusion imaging. Journal Of Nuclear Cardiology 2022, 30: 590-603. PMID: 36195826, DOI: 10.1007/s12350-022-03099-x.
• Deep-learning-based estimation of attenuation map improves attenuation correction performance over direct attenuation estimation for myocardial perfusion SPECTDu Y, Shang J, Sun J, Wang L, Liu YH, Xu H, Mok GSP. Deep-learning-based estimation of attenuation map improves attenuation correction performance over direct attenuation estimation for myocardial perfusion SPECT. Journal Of Nuclear Cardiology 2022, 30: 1022-1037. PMID: 36097242, DOI: 10.1007/s12350-022-03092-4.
• Potential Impact of SPECT Resolution on Quantification of Left Ventricular Volumes and Ejection Fraction: A Phantom StudyLiu H, Aslan M, Sandoval V, Liu Y. Potential Impact of SPECT Resolution on Quantification of Left Ventricular Volumes and Ejection Fraction: A Phantom Study. Journal Of Medical And Biological Engineering 2022, 42: 734-743. DOI: 10.1007/s40846-022-00747-y.
• Deep learning-based denoising in projection-domain and reconstruction-domain for low-dose myocardial perfusion SPECTSun J, Jiang H, Du Y, Li C, Wu T, Liu Y, Yang B, Mok G. Deep learning-based denoising in projection-domain and reconstruction-domain for low-dose myocardial perfusion SPECT. Journal Of Nuclear Cardiology 2022, 30: 970-985. PMID: 35982208, DOI: 10.1007/s12350-022-03045-x.
• Deep-Learning-Based Few-Angle Cardiac SPECT Reconstruction Using TransformerXie H, Thorn S, Liu Y, Lee S, Liu Z, Wang G, Sinusas A, Liu C. Deep-Learning-Based Few-Angle Cardiac SPECT Reconstruction Using Transformer. IEEE Transactions On Radiation And Plasma Medical Sciences 2022, 7: 33-40. PMID: 37397179, PMCID: PMC10312390, DOI: 10.1109/trpms.2022.3187595.
• Increasing angular sampling through deep learning for stationary cardiac SPECT image reconstructionXie H, Thorn S, Chen X, Zhou B, Liu H, Liu Z, Lee S, Wang G, Liu YH, Sinusas AJ, Liu C. Increasing angular sampling through deep learning for stationary cardiac SPECT image reconstruction. Journal Of Nuclear Cardiology 2022, 30: 86-100. PMID: 35508796, DOI: 10.1007/s12350-022-02972-z.
• Direct and indirect strategies of deep-learning-based attenuation correction for general purpose and dedicated cardiac SPECTChen X, Zhou B, Xie H, Shi L, Liu H, Holler W, Lin M, Liu YH, Miller EJ, Sinusas AJ, Liu C. Direct and indirect strategies of deep-learning-based attenuation correction for general purpose and dedicated cardiac SPECT. European Journal Of Nuclear Medicine And Molecular Imaging 2022, 49: 3046-3060. PMID: 35169887, PMCID: PMC9253078, DOI: 10.1007/s00259-022-05718-8.
• Post-reconstruction attenuation correction for SPECT myocardium perfusion imaging facilitated by deep learning-based attenuation map generationLiu H, Wu J, Shi L, Liu Y, Miller E, Sinusas A, Liu YH, Liu C. Post-reconstruction attenuation correction for SPECT myocardium perfusion imaging facilitated by deep learning-based attenuation map generation. Journal Of Nuclear Cardiology 2021, 29: 2881-2892. PMID: 34671940, DOI: 10.1007/s12350-021-02817-1.
• Association Between Impaired Myocardial Flow Reserve on 82Rubidium Positron Emission Tomography Imaging and Adverse Events in Patients With Autoimmune Rheumatic DiseaseFeher A, Boutagy NE, Oikonomou EK, Liu YH, Miller EJ, Sinusas AJ, Hinchcliff M. Association Between Impaired Myocardial Flow Reserve on 82Rubidium Positron Emission Tomography Imaging and Adverse Events in Patients With Autoimmune Rheumatic Disease. Circulation Cardiovascular Imaging 2021, 14: e012208. PMID: 34503339, PMCID: PMC8475774, DOI: 10.1161/circimaging.120.012208.
• Impaired Myocardial Flow Reserve on 82Rubidium Positron Emission Tomography/Computed Tomography in Patients With Systemic Sclerosis.Feher A, Boutagy NE, Oikonomou EK, Thorn S, Liu YH, Miller EJ, Sinusas AJ, Hinchcliff M. Impaired Myocardial Flow Reserve on 82Rubidium Positron Emission Tomography/Computed Tomography in Patients With Systemic Sclerosis. The Journal Of Rheumatology 2021, 48: 1574-1582. PMID: 34266986, PMCID: PMC10275580, DOI: 10.3899/jrheum.210040.
• Diagnostic accuracy of stress-only myocardial perfusion SPECT improved by deep learningLiu H, Wu J, Miller EJ, Liu C, Yaqiang, Liu, Liu YH. Diagnostic accuracy of stress-only myocardial perfusion SPECT improved by deep learning. European Journal Of Nuclear Medicine And Molecular Imaging 2021, 48: 2793-2800. PMID: 33511425, DOI: 10.1007/s00259-021-05202-9.
• Abstract 16617: Multimodality Imaging Approach in Delivery and Tracking of a Novel Imageable Hydrogel in a Chronic Porcine Infarct ModelMelvinsdottir I, Lee S, Avendano R, Midgett D, Liu Y, Thorn S, hawley C, Mamarian M, Uman S, Humphrey J, Duncan J, Burdick J, Sinusas A. Abstract 16617: Multimodality Imaging Approach in Delivery and Tracking of a Novel Imageable Hydrogel in a Chronic Porcine Infarct Model. Circulation 2020, 142 DOI: 10.1161/circ.142.suppl_3.16617.
• Anger recall mental stress decreases 123I-metaiodobenzylguanidine (123I-MIBG) uptake and increases heterogeneity of cardiac sympathetic activity in the myocardium in patients with ischemic cardiomyopathyAvendaño R, Hashemi-Zonouz T, Sandoval V, Liu C, Burg M, Sinusas AJ, Lampert R, Liu YH. Anger recall mental stress decreases 123I-metaiodobenzylguanidine (123I-MIBG) uptake and increases heterogeneity of cardiac sympathetic activity in the myocardium in patients with ischemic cardiomyopathy. Journal Of Nuclear Cardiology 2020, 29: 798-809. PMID: 33034036, DOI: 10.1007/s12350-020-02372-1.
• Noise reduction with cross-tracer and cross-protocol deep transfer learning for low-dose PETLiu H, Wu J, Lu W, Onofrey JA, Liu YH, Liu C. Noise reduction with cross-tracer and cross-protocol deep transfer learning for low-dose PET. Physics In Medicine And Biology 2020, 65: 185006. PMID: 32924973, DOI: 10.1088/1361-6560/abae08.
• Quantification of myocardial blood flow (MBF) and reserve (MFR) incorporated with a novel segmentation approach: Assessments of quantitative precision and the lower limit of normal MBF and MFR in patientsLiu H, Thorn S, Wu J, Fazzone-Chettiar R, Sandoval V, Miller EJ, Sinusas AJ, Liu YH. Quantification of myocardial blood flow (MBF) and reserve (MFR) incorporated with a novel segmentation approach: Assessments of quantitative precision and the lower limit of normal MBF and MFR in patients. Journal Of Nuclear Cardiology 2020, 28: 1236-1248. PMID: 32715416, DOI: 10.1007/s12350-020-02278-y.
• Multimodality Imaging Approach To Evaluate The Delivery And Impact Of A Novel Imageable Theranostic Hydrogel Post Myocardial Infarction In A Chronic Porcine ModelMelvinsdottir I, Lee S, Avendano R, Midgett D, Thorn S, Liu Y, Uman S, Humphrey J, Duncan J, Burdick J, Sinusas A. Multimodality Imaging Approach To Evaluate The Delivery And Impact Of A Novel Imageable Theranostic Hydrogel Post Myocardial Infarction In A Chronic Porcine Model. Journal Of Cardiovascular Computed Tomography 2020, 14: s27. DOI: 10.1016/j.jcct.2020.06.031.
• Deep learning-based attenuation map generation for myocardial perfusion SPECTShi L, Onofrey JA, Liu H, Liu YH, Liu C. Deep learning-based attenuation map generation for myocardial perfusion SPECT. European Journal Of Nuclear Medicine And Molecular Imaging 2020, 47: 2383-2395. PMID: 32219492, DOI: 10.1007/s00259-020-04746-6.
• A robust segmentation method with triple‐factor non‐negative matrix factorization for myocardial blood flow quantification from dynamic 82Rb positron emission tomographyLiu H, Wu J, Sun J, Wu T, Fazzone‐Chettiar R, Thorn S, Sinusas AJ, Liu Y. A robust segmentation method with triple‐factor non‐negative matrix factorization for myocardial blood flow quantification from dynamic 82Rb positron emission tomography. Medical Physics 2019, 46: 5002-5013. PMID: 31444909, DOI: 10.1002/mp.13783.
• P289SPECT camera head configuration, acquisition time, and resolution recovery processing impact image defect size quantificationStendahl J, Weyman C, Liu Y, Liu C, Miller E, Sinusas A. P289SPECT camera head configuration, acquisition time, and resolution recovery processing impact image defect size quantification. European Heart Journal - Cardiovascular Imaging 2019, 20: jez148.018. DOI: 10.1093/ehjci/jez148.018.
• A new approach to quantification of end-diastolic volume and ejection fraction from SPECT equilibrium radionuclide angiocardiography: methodology and phantom validation.Hashemi-Zonouz T, Wu J, Sandoval V, Allahverdi SH, Fazzone-Chettiar R, Liu Y-H. A new approach to quantification of end-diastolic volume and ejection fraction from SPECT equilibrium radionuclide angiocardiography: methodology and phantom validation. J Med Biol Eng 2019; 39:393-402.
• A Novel Three-Dimensional Clustering Method Incorporated with Ellipsoid Model Fitting for Personalizing Myocardial Perfusion Positron Emission Tomography Image SegmentationSun J, Wu T, Liu H, Liu Y. A Novel Three-Dimensional Clustering Method Incorporated with Ellipsoid Model Fitting for Personalizing Myocardial Perfusion Positron Emission Tomography Image Segmentation. 2018, 00: 1-4. DOI: 10.1109/nssmic.2018.8824346.
• New Method for Quantification of the Left Ventricular Function from Low-dose Equilibrium Radionuclide Angiocardiography: Comparisons with Conventional Methods in PatientsLiu Y, Tsatkin V, Fazzone-Chettiar R, Miller E, Sinusas A. New Method for Quantification of the Left Ventricular Function from Low-dose Equilibrium Radionuclide Angiocardiography: Comparisons with Conventional Methods in Patients. 2018, 00: 1-3. DOI: 10.1109/nssmic.2018.8824749.
• A New Approach to Quantification of End-Diastolic Volume and Ejection Fraction from SPECT Equilibrium Radionuclide Angiocardiography: Methodology and Phantom ValidationHashemi-Zonouz T, Wu J, Sandoval V, Allahverdi S, Fazzone-Chettiar R, Liu Y. A New Approach to Quantification of End-Diastolic Volume and Ejection Fraction from SPECT Equilibrium Radionuclide Angiocardiography: Methodology and Phantom Validation. Journal Of Medical And Biological Engineering 2018, 39: 393-402. DOI: 10.1007/s40846-018-0413-y.
• SUV QUANTIFICATION OF 99MTC-PYP IMAGING IN TTR-CARDIAC AMYLOIDOSIS USING A CZT CAMERA: A NEW TOOL IN THE ARMAMENTARIUMSikanderkhel S, Liu Y, Liu C, Miller E. SUV QUANTIFICATION OF 99MTC-PYP IMAGING IN TTR-CARDIAC AMYLOIDOSIS USING A CZT CAMERA: A NEW TOOL IN THE ARMAMENTARIUM. Journal Of The American College Of Cardiology 2018, 71: a1689. DOI: 10.1016/s0735-1097(18)32230-7.
• A blind deconvolution method incorporated with anatomical‐based filtering for partial volume correction: Validations with 123I‐mIBG cardiac SPECT/CTWu J, Liu H, Zonouz T, Sandoval VM, Mohy‐ud‐Din H, Lampert RJ, Sinusas AJ, Liu C, Liu Y. A blind deconvolution method incorporated with anatomical‐based filtering for partial volume correction: Validations with 123I‐mIBG cardiac SPECT/CT. Medical Physics 2017, 44: 6435-6446. PMID: 28994458, DOI: 10.1002/mp.12622.
• Quantification and Determination of Normal 123I-Meta Iodobenzylguanidine Heart-to-Mediastinum Ratio (HMR) from Cardiac SPECT/CT and Correlation with Planar HMRAlvi R, Miller EJ, Zonouz TH, Sandoval V, Tariq N, Lampert R, Sinusas AJ, Liu YH. Quantification and Determination of Normal 123I-Meta Iodobenzylguanidine Heart-to-Mediastinum Ratio (HMR) from Cardiac SPECT/CT and Correlation with Planar HMR. Journal Of Nuclear Medicine 2017, 59: 652-658. PMID: 28916622, DOI: 10.2967/jnumed.117.197152.
• Hybrid Imaging in Cardioavascular MedicineYi-Hwa Liu and Albert J. Sinusas, CRC Press, Taylor & Francis Group, London, UK, 2017 (ISBN: 978-1-4665-9537-8).
• NORMAL LIMITS OF HEART-TO-MEDIASTINUM RATIO (HMR) OF I-123 MIBG UPTAKE QUANTIFIED FROM HIGH-SENSITIVITY (HS) AND HIGH-RESOLUTION (HR) SPECT/CTLiu Y, Zonouz T, Sandoval V, Lampert R, Sinusas A. NORMAL LIMITS OF HEART-TO-MEDIASTINUM RATIO (HMR) OF I-123 MIBG UPTAKE QUANTIFIED FROM HIGH-SENSITIVITY (HS) AND HIGH-RESOLUTION (HR) SPECT/CT. Journal Of The American College Of Cardiology 2016, 67: 1822. DOI: 10.1016/s0735-1097(16)31823-x.
• SPECT Imaging of 2-D and 3-D Distributed Sources with Near-Field Coded Aperture Collimation: Computer Simulation and Real Data ValidationMu Z, Dobrucki LW, Liu YH. SPECT Imaging of 2-D and 3-D Distributed Sources with Near-Field Coded Aperture Collimation: Computer Simulation and Real Data Validation. Journal Of Medical And Biological Engineering 2016, 36: 32-43. PMID: 27069461, PMCID: PMC4791458, DOI: 10.1007/s40846-016-0111-6.
• High-Sensitivity and High-Resolution SPECT/CT Systems Provide Substantial Dose Reduction Without Compromising Quantitative Precision for Assessment of Myocardial Perfusion and FunctionPalyo RJ, Sinusas A, Liu YH. High-Sensitivity and High-Resolution SPECT/CT Systems Provide Substantial Dose Reduction Without Compromising Quantitative Precision for Assessment of Myocardial Perfusion and Function. Journal Of Nuclear Medicine 2016, 57: 893-899. PMID: 26848173, DOI: 10.2967/jnumed.115.164632.
• Prerequisite of SPECT/CT Image Segmentation Approach Potentially Leading to Precise Absolute Quantification of Myocardial Focal Tracer Uptake: Phantom and Canine ValidationsLiu Y, Prasad R, Li S. Prerequisite of SPECT/CT Image Segmentation Approach Potentially Leading to Precise Absolute Quantification of Myocardial Focal Tracer Uptake: Phantom and Canine Validations. 2014, 1-3. DOI: 10.1109/nssmic.2014.7430786.
• New Approach to Quantification of Molecularly Targeted Radiotracer Uptake from Hybrid Cardiac SPECT/CT: Methodology and ValidationLi S, Sinusas AJ, Dobrucki LW, Liu YH. New Approach to Quantification of Molecularly Targeted Radiotracer Uptake from Hybrid Cardiac SPECT/CT: Methodology and Validation. Journal Of Nuclear Medicine 2013, 54: 2175-2181. PMID: 24221992, DOI: 10.2967/jnumed.113.123208.
• Potential Impact of Hybrid CZT SPECT/CT Imaging on Estimation Accuracy of Left Ventricular Volumes and Ejection Fraction: A Phantom StudyLiu Y, Sandoval V, Sinusas A. Potential Impact of Hybrid CZT SPECT/CT Imaging on Estimation Accuracy of Left Ventricular Volumes and Ejection Fraction: A Phantom Study. 2013, 1-5. DOI: 10.1109/nssmic.2013.6829398.
• FastMIST: A Fast Molecular Imaging SimulaTorRyder W, Angelis G, Bashar R, Kyme A, Fulton R, Liu Y, Meikle S. FastMIST: A Fast Molecular Imaging SimulaTor. 2011 IEEE Nuclear Science Symposium Conference Record 2013, 2723-2726. DOI: 10.1109/nssmic.2012.6551619.
• Left Ventricular Ejection Fraction and Left Ventricular End‐Diastolic Volume in Patients With Diastolic DysfunctionJovin IS, Ebisu K, Liu Y, Finta LA, Oprea AD, Brandt CA, Dziura J, Wackers FJ. Left Ventricular Ejection Fraction and Left Ventricular End‐Diastolic Volume in Patients With Diastolic Dysfunction. Congestive Heart Failure 2012, 19: 130-134. PMID: 23241105, DOI: 10.1111/chf.12013.
• 82RB POSITRON EMISSION TOMOGRAPHY (PET) MYOCARDIAL BLOOD FLOW (MBF) CORRELATES WITH CORONARY ARTERY INTIMAL THICKNESS MEASURED BY INTRAVASCULAR ULTRASOUND (IVUS) FOLLOWING HEART TRANSPLANTATIONMohani A, Khanna P, Liu Y, Sinusas A, Lee F. 82RB POSITRON EMISSION TOMOGRAPHY (PET) MYOCARDIAL BLOOD FLOW (MBF) CORRELATES WITH CORONARY ARTERY INTIMAL THICKNESS MEASURED BY INTRAVASCULAR ULTRASOUND (IVUS) FOLLOWING HEART TRANSPLANTATION. Journal Of The American College Of Cardiology 2011, 57: e848. DOI: 10.1016/s0735-1097(11)60848-6.
• Accuracy and Reproducibility of Absolute Quantification of Myocardial Focal Tracer Uptake from Molecularly Targeted SPECT/CT: A Canine ValidationLiu YH, Sahul Z, Weyman CA, Dione DP, Dobrucki WL, Mekkaoui C, Brennan MP, Ryder WJ, Sinusas AJ. Accuracy and Reproducibility of Absolute Quantification of Myocardial Focal Tracer Uptake from Molecularly Targeted SPECT/CT: A Canine Validation. Journal Of Nuclear Medicine 2011, 52: 453-460. PMID: 21321271, PMCID: PMC3137905, DOI: 10.2967/jnumed.110.082214.
• Cardiovascular ImagingYi-Hwa Liu and Frans J.Th Wackers, CRC Press, Taylor & Francis Group, London, UK, 2011(ISBN: 978-1-84076-109-2).
• Recent Progress on SPECT Imaging with Near-field Coded Aperture Collimation: A Small Animal StudyMu Z, Dobrucki W, Hu X, Liu Y. Recent Progress on SPECT Imaging with Near-field Coded Aperture Collimation: A Small Animal Study. 2010, 3450-3453. DOI: 10.1109/nssmic.2010.5874447.
• Cardiovascular ImagingLiu Y, Wackers F. Cardiovascular Imaging. 2009 DOI: 10.1201/b15123.
• A novel three‐dimensional image reconstruction method for near‐field coded aperture single photon emission computerized tomographyMu Z, Hong B, Li S, Liu Y. A novel three‐dimensional image reconstruction method for near‐field coded aperture single photon emission computerized tomography. Medical Physics 2009, 36: 1533-1542. PMID: 19544769, PMCID: PMC2832028, DOI: 10.1118/1.3103490.
• Hotspot quantification of myocardial focal tracer uptake from molecular targeted SPECT/CT images: experimental validationLiu Y, Sahul Z, Weyman C, Ryder W, Dione D, Dobrucki L, Mekkaoui C, Brennan M, Hu X, Hawley C, Sinusas A. Hotspot quantification of myocardial focal tracer uptake from molecular targeted SPECT/CT images: experimental validation. Proceedings Of SPIE--the International Society For Optical Engineering 2008, 6915: 69150n-69150n-8. DOI: 10.1117/12.768985.
• Generic iterative reconstruction of multi-pinhole SPECTRyder W, Brennan M, Sinusas A, Liu Y. Generic iterative reconstruction of multi-pinhole SPECT. Proceedings Of SPIE--the International Society For Optical Engineering 2008, 6913: 69132m-69132m-10. DOI: 10.1117/12.769519.
• Quantification of nuclear cardiac images: The Yale approachLiu YH. Quantification of nuclear cardiac images: The Yale approach. Journal Of Nuclear Cardiology 2007, 14: 483-491. PMID: 17679055, DOI: 10.1016/j.nuclcard.2007.06.005.
• 6.4 New method of scatter correction for quantification of molecular targeted cardiac images: canine validationLiu Y, Weyman C, Dione D, Sahul Z, Dobrucki W, Brennan M, Mekkaoui C, Sinusas A. 6.4 New method of scatter correction for quantification of molecular targeted cardiac images: canine validation. Journal Of Nuclear Cardiology 2007, 14: s39. DOI: 10.1016/j.nuclcard.2006.12.157.
• A New Method for Hot-Spot Quantification of Hybrid SPECT/CT Cardiac Images: Methodology and Preliminary Phantom ValidationLiu Y, Fernando G, Sinusas A. A New Method for Hot-Spot Quantification of Hybrid SPECT/CT Cardiac Images: Methodology and Preliminary Phantom Validation. IEEE Transactions On Nuclear Science 2006, 53: 2814-2821. DOI: 10.1109/tns.2006.879823.
• Aperture Collimation Correction and Maximum-Likelihood Image Reconstruction for Near-Field Coded Aperture Imaging of Single Photon Emission Computerized TomographyMu Z, Liu YH. Aperture Collimation Correction and Maximum-Likelihood Image Reconstruction for Near-Field Coded Aperture Imaging of Single Photon Emission Computerized Tomography. IEEE Transactions On Medical Imaging 2006, 25: 701-711. PMID: 16768235, DOI: 10.1109/tmi.2006.873298.
• A new approach of 3D SPECT reconstruction for near-field coded aperture imagingHong B, Mu Z, Liu Y. A new approach of 3D SPECT reconstruction for near-field coded aperture imaging. Proceedings Of SPIE--the International Society For Optical Engineering 2006, 6142: 61424d-61424d-8. DOI: 10.1117/12.653300.
• A stochastic approach for quantification of hotspot focal uptake from cardiac SPECT/CT images: A canine validationLiu Y, Li S, Bourke B, Weyman C, Sinusas A. A stochastic approach for quantification of hotspot focal uptake from cardiac SPECT/CT images: A canine validation. Journal Of Nuclear Cardiology 2005, 12: s73. DOI: 10.1016/j.nuclcard.2004.12.169.
• A Geometry- and Count-Based Method for Gated Spect Quantification of Myocardial Thickness, Left Ventricular Volume, and Ejection FractionLiu Y, Khaimov D. A Geometry- and Count-Based Method for Gated Spect Quantification of Myocardial Thickness, Left Ventricular Volume, and Ejection Fraction. IEEE Transactions On Nuclear Science 2005, 52: 159-165. DOI: 10.1109/tns.2005.843621.
• A New Method for SPECT Quantification of Targeted Radiotracers Uptake in the MyocardiumLi S, Dobrucki LW, Sinusas AJ, Liu YH. A New Method for SPECT Quantification of Targeted Radiotracers Uptake in the Myocardium. 2005, 8: 684-691. PMID: 16686019, DOI: 10.1007/11566489_84.
• New hybrid count- and geometry-based method for quantification of left ventricular volumes and ejection fraction from ECG-gated SPECT: Methodology and validationLiu YH, Sinusas AJ, Khaimov D, Gebuza BI, Wackers FJ. New hybrid count- and geometry-based method for quantification of left ventricular volumes and ejection fraction from ECG-gated SPECT: Methodology and validation. Journal Of Nuclear Cardiology 2005, 12: 55-65. PMID: 15682366, DOI: 10.1016/j.nuclcard.2004.09.015.
• 804-1 18-f-fluoro-2-deoxyglucose as a memory marker of transient myocardial ischemiaAbbott B, Liu Y, Arrighi J. 804-1 18-f-fluoro-2-deoxyglucose as a memory marker of transient myocardial ischemia. Journal Of The American College Of Cardiology 2004, 43: a332. DOI: 10.1016/s0735-1097(04)91405-2.
• Gated SPECT Quantification for Myocardial Thickness, Left Ventricular Volumes and Ejection Fraction: Methodology and Phantom ValidationLiu Y, Khaimov D, Sinusas A, Wackers F. Gated SPECT Quantification for Myocardial Thickness, Left Ventricular Volumes and Ejection Fraction: Methodology and Phantom Validation. 2003, 4: 2955-2959. DOI: 10.1109/nssmic.2003.1352503.
• Quantification of regional myocardial wall thickening on electrocardiogram-gated SPECT imagingShen M, Liu Y, Sinusas A, Fetterman R, Bruni W, Drozhinin O, Zaret B, Wackers F. Quantification of regional myocardial wall thickening on electrocardiogram-gated SPECT imaging. Journal Of Nuclear Cardiology 1999, 6: 583-595. PMID: 10608585, DOI: 10.1016/s1071-3581(99)90095-8.
• Quantification of SPECT myocardial perfusion images: Methodology and validation of the Yale-CQ methodLiu Y, Sinusas A, DeMan P, Zaret B, Wackers F. Quantification of SPECT myocardial perfusion images: Methodology and validation of the Yale-CQ method. Journal Of Nuclear Cardiology 1999, 6: 190-203. PMID: 10327104, DOI: 10.1016/s1071-3581(99)90080-6.
• A novel geometry for SPECT imaging associated with the EM-type blind deconvolution methodLiu Y, Rangarajan A, Gagnon D, Therrien M, Sinusas A, Wackers F, Zubal I. A novel geometry for SPECT imaging associated with the EM-type blind deconvolution method. IEEE Transactions On Nuclear Science 1998, 45: 2095-2101. DOI: 10.1109/23.708310.
• New methods for SPECT imaging and pre-reconstruction restorationLiu Y, Rangarajan A, Gagnon D, Therrien M, Sinusas A, Wackers F, Zubal G. New methods for SPECT imaging and pre-reconstruction restoration. 1997, 1230: 531-536. DOI: 10.1007/3-540-63046-5_55.
• The Yale-CQ method for cardiac SPECT quantification: phantom validation and patient applicationLiu Y, DeMan P, Sinusas A, Natale D, Wackers F. The Yale-CQ method for cardiac SPECT quantification: phantom validation and patient application. 1997, 3: 1091-1093 vol.3. DOI: 10.1109/iembs.1996.652723.
• A novel geometry for SPECT imaging associated with the EM-type blind deconvolution methodLiu Y, Rangarajan A, Gagnon D, Therrien M, Sinusas A, Wackers F, Zubal I. A novel geometry for SPECT imaging associated with the EM-type blind deconvolution method. 2011 IEEE Nuclear Science Symposium Conference Record 1997, 2: 1014-1017 vol.2. DOI: 10.1109/nssmic.1997.670482.
• Quantification of technetium 99m-labeled sestamibi single-photon emission computed tomography based on mean counts improves accuracy for assessment of relative regional myocardial blood flow: Experimental validation in a canine modelLiu Y, Sinusas A, Shi C, Shen M, Dione D, Heller E, Wackers F. Quantification of technetium 99m-labeled sestamibi single-photon emission computed tomography based on mean counts improves accuracy for assessment of relative regional myocardial blood flow: Experimental validation in a canine model. Journal Of Nuclear Cardiology 1996, 3: 312-320. PMID: 8799250, DOI: 10.1016/s1071-3581(96)90091-4.
• Detection of myocardial ischemia with dynamic SPECT I-123-lodophenylpentadecanoic acid (IPPA) imagingDaher E, Shi C, Heller E, Liu Y, DeMan P, Dione D, Wackers F, Sinusas A. Detection of myocardial ischemia with dynamic SPECT I-123-lodophenylpentadecanoic acid (IPPA) imaging. Journal Of The American College Of Cardiology 1996, 27: 407-408. DOI: 10.1016/s0735-1097(96)82567-8.
• Blind deconvolution of fluorescence micrographs by maximum-likelihood estimation.Krishnamurthi V, Liu Y, Bhattacharyya S, Turner J, Holmes T. Blind deconvolution of fluorescence micrographs by maximum-likelihood estimation. Applied Optics 1995, 34: 6633-47. PMID: 21060518, DOI: 10.1364/ao.34.006633.
• Phantom evaluation of non-uniform attenuation correction using simultaneous transmission emission SPECTDeMan P, Eror E, Liu Y, Mattera J, Wackers F, Sinusas A. Phantom evaluation of non-uniform attenuation correction using simultaneous transmission emission SPECT. Journal Of Nuclear Cardiology 1995, 2: s48. DOI: 10.1016/s1071-3581(05)80276-4.
• Validation of a new SPECT quantification method using computer simulationLiu Y, Sinusas A, Wackers F. Validation of a new SPECT quantification method using computer simulation. 1995, 3: 1506-1509 vol.3. DOI: 10.1109/nssmic.1995.500312.
• An automated approach for quantification of relative regional myocardial blood flow, using SPECT Tc99m-sestamibi: preliminary validation in a canine modelLiu Y, Sinusas A, Shi C, Shen M, Dione D, Duncan J, Wackers F. An automated approach for quantification of relative regional myocardial blood flow, using SPECT Tc99m-sestamibi: preliminary validation in a canine model. 1994, 1: 636-638 vol.1. DOI: 10.1109/iembs.1994.411839.
• Three-dimensional image reconstruction of fluorescence micrographs without knowing the point spread functionHolmes T, Krishnamurthi V, Liu Y. Three-dimensional image reconstruction of fluorescence micrographs without knowing the point spread function. Microscopy And Microanalysis 1993, 51: 152-153. DOI: 10.1017/s0424820100146606.
• Blind deconvolution of 2-D and 3-D fluorescent micrographsKrishnamurthi V, Liu Y, Holmes T, Roysam B, Turner J. Blind deconvolution of 2-D and 3-D fluorescent micrographs. Proceedings Of SPIE--the International Society For Optical Engineering 1992, 1660: 95-102. DOI: 10.1117/12.59544.
• Increased depth of field and stereo pairs of fluorescence micrographs via inverse filtering and maximum‐likelihood estimationHolmes T, Liu Y, Khosla D, Agard D. Increased depth of field and stereo pairs of fluorescence micrographs via inverse filtering and maximum‐likelihood estimation. Journal Of Microscopy 1991, 164: 217-237. DOI: 10.1111/j.1365-2818.1991.tb03209.x.
• Acceleration of maximum-likelihood image restoration for fluorescence microscopy and other noncoherent imageryHolmes T, Liu Y. Acceleration of maximum-likelihood image restoration for fluorescence microscopy and other noncoherent imagery. Journal Of The Optical Society Of America A 1991, 8: 893. DOI: 10.1364/josaa.8.000893.
• Preliminary tests of maximum likelihood image reconstruction method on 3-D real data and some practical considerations for the data correctionsLiu Y, Holmes T, Koshy M. Preliminary tests of maximum likelihood image reconstruction method on 3-D real data and some practical considerations for the data corrections. Proceedings Of SPIE--the International Society For Optical Engineering 1991, 1428: 191-199. DOI: 10.1117/12.44141.
• Simulation Tests Of Restoring Truncated Fluorescence MicrographsHolmes T, Liu Y. Simulation Tests Of Restoring Truncated Fluorescence Micrographs. Proceedings Of SPIE--the International Society For Optical Engineering 1989, 1161: 197-204. DOI: 10.1117/12.962699.
• Richardson-Lucy/maximum likelihood image restoration algorithm for fluorescence microscopy: further testing.Holmes T, Liu Y. Richardson-Lucy/maximum likelihood image restoration algorithm for fluorescence microscopy: further testing. Applied Optics 1989, 28: 4930-8. PMID: 20555971, DOI: 10.1364/ao.28.004930.