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Pallavi Gopal, MD, PhD

Assistant Professor of Pathology

Contact Information

Pallavi Gopal, MD, PhD

Office Location

  • 310 Cedar Street, Rm LH108
    New Haven, CT 06510

Mailing Address

  • Yale School of Medicine

    Department of Pathology, P.O. Box 208023

    New Haven, CT 06520-8023

    United States

Research Summary

The Gopal lab is broadly interested in mRNA transport, RNA metabolism and its regulation in healthy and diseased neurons. As a physician-scientist, Dr. Gopal’s research aims to bridge neuronal cell biology and neuropathology of neurodegenerative disease. Her post-doctoral research provided new insight into the biophysical properties of neuronal ribonucleoprotein (RNP) granules and has shown that ALS-linked mutations fundamentally perturb the dynamic properties and transport of neuronal RNP complexes. The focus of the Gopal lab is to elucidate the molecular mechanisms driving neuronal RNP granule assembly, the spatiotemporal maturation and function of diverse RNP granules in neuronal physiology, and pathologic transitions in disease.


Research Interests

Amyotrophic Lateral Sclerosis; Autopsy; Cell Biology; Neurons; Ribonucleoproteins; Neurodegenerative Diseases; RNA Transport; Frontotemporal Lobar Degeneration; TDP-43 Proteinopathies

Selected Publications