Batur Gultekin, BSc (Hon)
Research & Publications
Biography
Locations
Research Summary
Gunel Lab utilizes state of the art genomics techniques and complex bioinformatic analysis for gene discovery followed by functional studies to pursue three major research interests; developmental neurogenetic disorders, neurovascular disorders and tumor Biology. The overall goal of the lab is to understand the biology of these disorders and help design better/novel diagnostics, therapeutics and non-invasive treatments for these diseases.
Extensive Research Description
I am conducting research on the contribution of population-rare germline mutations in cerebrovascular disorders including intracranial aneurysms as well as structural brain malformations including microcephaly. I am taking part in both computational and wet lab aspects of the research projects at Neurogenetics laboratory of Professor Murat Gunel, MD.
Coauthors
Research Interests
Genetics; Molecular Biology; Neurobiology; Neurosciences; Computational Biology; Machine Learning
Public Health Interests
Bioinformatics
Selected Publications
- PPIL4 is essential for brain angiogenesis and implicated in intracranial aneurysms in humansBarak T, Ristori E, Ercan-Sencicek AG, Miyagishima DF, Nelson-Williams C, Dong W, Jin SC, Prendergast A, Armero W, Henegariu O, Erson-Omay EZ, Harmancı AS, Guy M, Gültekin B, Kilic D, Rai DK, Goc N, Aguilera SM, Gülez B, Altinok S, Ozcan K, Yarman Y, Coskun S, Sempou E, Deniz E, Hintzen J, Cox A, Fomchenko E, Jung SW, Ozturk AK, Louvi A, Bilgüvar K, Connolly ES, Khokha MK, Kahle KT, Yasuno K, Lifton RP, Mishra-Gorur K, Nicoli S, Günel M. PPIL4 is essential for brain angiogenesis and implicated in intracranial aneurysms in humans. Nature Medicine 2021, 27: 2165-2175. PMID: 34887573, PMCID: PMC8768030, DOI: 10.1038/s41591-021-01572-7.
- Clinical trial publication trends within neurologyDuy PQ, Sreekrishnan A, David W, Paranjpe MD, Paranjpe I, Sheth A, Gültekin B, Sheth KN. Clinical trial publication trends within neurology. Translational Neuroscience 2019, 10: 233-234. PMID: 31497319, PMCID: PMC6708287, DOI: 10.1515/tnsci-2019-0037.