Andrew Prendergast, BA, PhD
Scientific Director
Research & Publications
Biography
News
Locations
Coauthors
Selected Publications
- Sensory Systems in the Peripheral and Central Nervous Systems Shape Host Response During InfectionsWyart C, Jim K, Prendergast A. Sensory Systems in the Peripheral and Central Nervous Systems Shape Host Response During Infections. Neuroscience 2023, 525: 47-50. PMID: 37419406, DOI: 10.1016/j.neuroscience.2023.07.008.
- CSF-contacting neurons respond to Streptococcus pneumoniae and promote host survival during central nervous system infectionPrendergast A, Jim K, Marnas H, Desban L, Quan F, Djenoune L, Laghi V, Hocquemiller A, Lunsford E, Roussel J, Keiser L, Lejeune F, Dhanasekar M, Bardet P, Levraud J, van de Beek D, Vandenbroucke-Grauls C, Wyart C. CSF-contacting neurons respond to Streptococcus pneumoniae and promote host survival during central nervous system infection. Current Biology 2023, 33: 940-956.e10. PMID: 36791723, DOI: 10.1016/j.cub.2023.01.039.
- Phenotyping Zebrafish Mutant Models to Assess Candidate Genes Associated with Aortic AneurysmPrendergast A, Ziganshin BA, Papanikolaou D, Zafar MA, Nicoli S, Mukherjee S, Elefteriades JA. Phenotyping Zebrafish Mutant Models to Assess Candidate Genes Associated with Aortic Aneurysm. Genes 2022, 13: 123. PMID: 35052463, PMCID: PMC8775119, DOI: 10.3390/genes13010123.
- PPIL4 is essential for brain angiogenesis and implicated in intracranial aneurysms in humansBarak T, Ristori E, Ercan-Sencicek AG, Miyagishima DF, Nelson-Williams C, Dong W, Jin SC, Prendergast A, Armero W, Henegariu O, Erson-Omay EZ, Harmancı AS, Guy M, Gültekin B, Kilic D, Rai DK, Goc N, Aguilera SM, Gülez B, Altinok S, Ozcan K, Yarman Y, Coskun S, Sempou E, Deniz E, Hintzen J, Cox A, Fomchenko E, Jung SW, Ozturk AK, Louvi A, Bilgüvar K, Connolly ES, Khokha MK, Kahle KT, Yasuno K, Lifton RP, Mishra-Gorur K, Nicoli S, Günel M. PPIL4 is essential for brain angiogenesis and implicated in intracranial aneurysms in humans. Nature Medicine 2021, 27: 2165-2175. PMID: 34887573, PMCID: PMC8768030, DOI: 10.1038/s41591-021-01572-7.
- Experience, circuit dynamics and forebrain recruitment in larval zebrafish prey captureOldfield C, Grossrubatscher I, Chávez M, Hoagland A, Huth A, Carroll E, Prendergast A, Qu T, Gallant J, Wyart C, Isacoff E. Experience, circuit dynamics and forebrain recruitment in larval zebrafish prey capture. ELife 2020, 9: e56619. PMID: 32985972, PMCID: PMC7561350, DOI: 10.7554/elife.56619.
- Glia: A Gate Controlling Animal Behavior?Wyart C, Prendergast A. Glia: A Gate Controlling Animal Behavior? Current Biology 2019, 29: r847-r850. PMID: 31505186, DOI: 10.1016/j.cub.2019.07.058.
- Regulation of the apical extension morphogenesis tunes the mechanosensory response of microvilliated neuronsDesban L, Prendergast A, Roussel J, Rosello M, Geny D, Wyart C, Bardet PL. Regulation of the apical extension morphogenesis tunes the mechanosensory response of microvilliated neurons. PLOS Biology 2019, 17: e3000235. PMID: 31002663, PMCID: PMC6493769, DOI: 10.1371/journal.pbio.3000235.
- Pkd2l1 is required for mechanoception in cerebrospinal fluid-contacting neurons and maintenance of spine curvatureSternberg JR, Prendergast AE, Brosse L, Cantaut-Belarif Y, Thouvenin O, Orts-Del’Immagine A, Castillo L, Djenoune L, Kurisu S, McDearmid JR, Bardet PL, Boccara C, Okamoto H, Delmas P, Wyart C. Pkd2l1 is required for mechanoception in cerebrospinal fluid-contacting neurons and maintenance of spine curvature. Nature Communications 2018, 9: 3804. PMID: 30228263, PMCID: PMC6143598, DOI: 10.1038/s41467-018-06225-x.
- Bioluminescence Monitoring of Neuronal Activity in Freely Moving Zebrafish Larvae.Knafo S, Prendergast A, Thouvenin O, Figueiredo SN, Wyart C. Bioluminescence Monitoring of Neuronal Activity in Freely Moving Zebrafish Larvae. Bio-protocol 2017, 7: e2550. PMID: 29130058, PMCID: PMC5681248, DOI: 10.21769/bioprotoc.2550.
- Mechanosensory neurons control the timing of spinal microcircuit selection during locomotionKnafo S, Fidelin K, Prendergast A, Tseng PB, Parrin A, Dickey C, Böhm UL, Figueiredo SN, Thouvenin O, Pascal-Moussellard H, Wyart C. Mechanosensory neurons control the timing of spinal microcircuit selection during locomotion. ELife 2017, 6: e25260. PMID: 28623664, PMCID: PMC5499942, DOI: 10.7554/elife.25260.
- The dual developmental origin of spinal cerebrospinal fluid-contacting neurons gives rise to distinct functional subtypesDjenoune L, Desban L, Gomez J, Sternberg JR, Prendergast A, Langui D, Quan FB, Marnas H, Auer TO, Rio JP, Del Bene F, Bardet PL, Wyart C. The dual developmental origin of spinal cerebrospinal fluid-contacting neurons gives rise to distinct functional subtypes. Scientific Reports 2017, 7: 719. PMID: 28389647, PMCID: PMC5428266, DOI: 10.1038/s41598-017-00350-1.
- Intraspinal Sensory Neurons Provide Powerful Inhibition to Motor Circuits Ensuring Postural Control during LocomotionHubbard JM, Böhm UL, Prendergast A, Tseng PB, Newman M, Stokes C, Wyart C. Intraspinal Sensory Neurons Provide Powerful Inhibition to Motor Circuits Ensuring Postural Control during Locomotion. Current Biology 2016, 26: 2841-2853. PMID: 27720623, DOI: 10.1016/j.cub.2016.08.026.
- Innervation regulates synaptic ribbons in lateral line mechanosensory hair cellsSuli A, Pujol R, Cunningham D, Hailey D, Prendergast A, Rubel E, Raible D. Innervation regulates synaptic ribbons in lateral line mechanosensory hair cells. Development 2016, 143: e1.2-e1.2. DOI: 10.1242/dev.140616.
- Remote z-scanning with a macroscopic voice coil motor for fast 3D multiphoton laser scanning microscopyRupprecht P, Prendergast A, Wyart C, Friedrich RW. Remote z-scanning with a macroscopic voice coil motor for fast 3D multiphoton laser scanning microscopy. Biomedical Optics Express 2016, 7: 1656-1671. PMID: 27231612, PMCID: PMC4871072, DOI: 10.1364/boe.7.001656.
- Reck enables cerebrovascular development by promoting canonical Wnt signalingUlrich F, Carretero-Ortega J, Menéndez J, Narvaez C, Sun B, Lancaster E, Pershad V, Trzaska S, Véliz E, Kamei M, Prendergast A, Kidd K, Shaw K, Castranova D, Pham V, Lo B, Martin B, Raible D, Weinstein B, Torres-Vázquez J. Reck enables cerebrovascular development by promoting canonical Wnt signaling. Development 2016, 143: 1055-1055. PMID: 26980794, PMCID: PMC4813290, DOI: 10.1242/dev.136507.
- CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuitsBöhm UL, Prendergast A, Djenoune L, Nunes Figueiredo S, Gomez J, Stokes C, Kaiser S, Suster M, Kawakami K, Charpentier M, Concordet JP, Rio JP, Del Bene F, Wyart C. CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits. Nature Communications 2016, 7: 10866. PMID: 26946992, PMCID: PMC4786674, DOI: 10.1038/ncomms10866.
- Locomotion: Electrical Coupling of Motor and Premotor NeuronsPrendergast A, Wyart C. Locomotion: Electrical Coupling of Motor and Premotor Neurons. Current Biology 2016, 26: r235-r237. PMID: 27003886, DOI: 10.1016/j.cub.2016.02.021.
- Innervation regulates synaptic ribbons in lateral line mechanosensory hair cellsSuli A, Pujol R, Cunningham DE, Hailey DW, Prendergast A, Rubel EW, Raible DW. Innervation regulates synaptic ribbons in lateral line mechanosensory hair cells. Journal Of Cell Science 2016, 129: 2250-2260. PMID: 27103160, PMCID: PMC4920245, DOI: 10.1242/jcs.182592.
- State-Dependent Modulation of Locomotion by GABAergic Spinal Sensory NeuronsFidelin K, Djenoune L, Stokes C, Prendergast A, Gomez J, Baradel A, Del Bene F, Wyart C. State-Dependent Modulation of Locomotion by GABAergic Spinal Sensory Neurons. Current Biology 2015, 25: 3035-3047. PMID: 26752076, DOI: 10.1016/j.cub.2015.09.070.
- Reck enables cerebrovascular development by promoting canonical Wnt signalingUlrich F, Carretero-Ortega J, Menéndez J, Narvaez C, Sun B, Lancaster E, Pershad V, Trzaska S, Véliz E, Kamei M, Prendergast A, Kidd KR, Shaw KM, Castranova DA, Pham VN, Lo BD, Martin BL, Raible DW, Weinstein BM, Torres-Vázquez J. Reck enables cerebrovascular development by promoting canonical Wnt signaling. Development 2015, 143: 147-159. PMID: 26657775, PMCID: PMC4725199, DOI: 10.1242/dev.123059.
- Chapter 13 Neural Crest Cells and Peripheral Nervous System DevelopmentPrendergast A, Raible D. Chapter 13 Neural Crest Cells and Peripheral Nervous System Development. 2014, 255-286. DOI: 10.1016/b978-0-12-401730-6.00014-4.
- Postembryonic neuronal addition in Zebrafish dorsal root ganglia is regulated by Notch signalingMcGraw HF, Snelson CD, Prendergast A, Suli A, Raible DW. Postembryonic neuronal addition in Zebrafish dorsal root ganglia is regulated by Notch signaling. Neural Development 2012, 7: 23. PMID: 22738203, PMCID: PMC3438120, DOI: 10.1186/1749-8104-7-23.
- The metalloproteinase inhibitor Reck is essential for zebrafish DRG developmentPrendergast A, Linbo TH, Swarts T, Ungos JM, McGraw HF, Krispin S, Weinstein BM, Raible DW. The metalloproteinase inhibitor Reck is essential for zebrafish DRG development. Development 2012, 139: 1141-1152. PMID: 22296847, PMCID: PMC3283124, DOI: 10.1242/dev.072439.
- Sensory neuron specification in the neural crest lineagePrendergast A, Linbo T, Swarts T, Ungos J, McGraw H, Raible D. Sensory neuron specification in the neural crest lineage. Developmental Biology 2011, 356: 118. DOI: 10.1016/j.ydbio.2011.05.058.
- Interplay between Foxd3 and Mitf regulates cell fate plasticity in the zebrafish neural crestCurran K, Lister JA, Kunkel GR, Prendergast A, Parichy DM, Raible DW. Interplay between Foxd3 and Mitf regulates cell fate plasticity in the zebrafish neural crest. Developmental Biology 2010, 344: 107-118. PMID: 20460180, PMCID: PMC2909359, DOI: 10.1016/j.ydbio.2010.04.023.
- Man is but a worm: Chordate originsBrown FD, Prendergast A, Swalla BJ. Man is but a worm: Chordate origins. Genesis 2008, 46: 605-613. PMID: 19003926, DOI: 10.1002/dvg.20471.