Nicola Micali, PhD
Associate Research Scientist in Neuroscience
Research & Publications
Biography
News
Coauthors
Selected Publications
- Molecular programs of regional specification and neural stem cell fate progression in macaque telencephalonMicali N, Ma S, Li M, Kim S, Mato-Blanco X, Sindhu S, Arellano J, Gao T, Shibata M, Gobeske K, Duque A, Santpere G, Sestan N, Rakic P. Molecular programs of regional specification and neural stem cell fate progression in macaque telencephalon. Science 2023, 382: eadf3786. PMID: 37824652, PMCID: PMC10705812, DOI: 10.1126/science.adf3786.
- Radial Glial Cells: New Views on Old QuestionsArellano JI, Morozov YM, Micali N, Rakic P. Radial Glial Cells: New Views on Old Questions. Neurochemical Research 2021, 46: 2512-2524. PMID: 33725233, PMCID: PMC8855517, DOI: 10.1007/s11064-021-03296-z.
- Variation of Human Neural Stem Cells Generating Organizer States In Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal FatesMicali N, Kim SK, Diaz-Bustamante M, Stein-O’Brien G, Seo S, Shin JH, Rash BG, Ma S, Wang Y, Olivares NA, Arellano JI, Maynard KR, Fertig EJ, Cross AJ, Bürli RW, Brandon NJ, Weinberger DR, Chenoweth JG, Hoeppner DJ, Sestan N, Rakic P, Colantuoni C, McKay RD. Variation of Human Neural Stem Cells Generating Organizer States In Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates. Cell Reports 2020, 31: 107599. PMID: 32375049, PMCID: PMC7357345, DOI: 10.1016/j.celrep.2020.107599.
- Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCsBurke EE, Chenoweth JG, Shin JH, Collado-Torres L, Kim SK, Micali N, Wang Y, Colantuoni C, Straub RE, Hoeppner DJ, Chen HY, Sellers A, Shibbani K, Hamersky GR, Diaz Bustamante M, Phan BN, Ulrich WS, Valencia C, Jaishankar A, Price AJ, Rajpurohit A, Semick SA, Bürli RW, Barrow JC, Hiler DJ, Page SC, Martinowich K, Hyde TM, Kleinman JE, Berman KF, Apud JA, Cross AJ, Brandon NJ, Weinberger DR, Maher BJ, McKay RDG, Jaffe AE. Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs. Nature Communications 2020, 11: 462. PMID: 31974374, PMCID: PMC6978526, DOI: 10.1038/s41467-019-14266-z.
- Gliogenesis in the outer subventricular zone promotes enlargement and gyrification of the primate cerebrumRash BG, Duque A, Morozov YM, Arellano JI, Micali N, Rakic P. Gliogenesis in the outer subventricular zone promotes enlargement and gyrification of the primate cerebrum. Proceedings Of The National Academy Of Sciences Of The United States Of America 2019, 116: 7089-7094. PMID: 30894491, PMCID: PMC6452694, DOI: 10.1073/pnas.1822169116.
- Metabolic regulation and glucose sensitivity of cortical radial glial cellsRash BG, Micali N, Huttner AJ, Morozov YM, Horvath TL, Rakic P. Metabolic regulation and glucose sensitivity of cortical radial glial cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 2018, 115: 10142-10147. PMID: 30224493, PMCID: PMC6176632, DOI: 10.1073/pnas.1808066115.
- FGF2 and Insulin Signaling Converge to Regulate Cyclin D Expression in Multipotent Neural Stem CellsAdepoju A, Micali N, Ogawa K, Hoeppner DJ, McKay RD. FGF2 and Insulin Signaling Converge to Regulate Cyclin D Expression in Multipotent Neural Stem Cells. Stem Cells 2014, 32: 770-778. PMID: 24155149, DOI: 10.1002/stem.1575.
- Homeodomain transcription factor and tumor suppressor Prep1 is required to maintain genomic stability.Iotti G, Longobardi E, Masella S, Dardaei L, De Santis F, Micali N, Blasi F. Homeodomain transcription factor and tumor suppressor Prep1 is required to maintain genomic stability. Proceedings Of The National Academy Of Sciences Of The United States Of America 2011, 108: E314-22. PMID: 21715654, PMCID: PMC3141938, DOI: 10.1073/pnas.1105216108.
- Down syndrome fibroblasts and mouse Prep1-overexpressing cells display increased sensitivity to genotoxic stress.Micali N, Longobardi E, Iotti G, Ferrai C, Castagnaro L, Ricciardi M, Blasi F, Crippa MP. Down syndrome fibroblasts and mouse Prep1-overexpressing cells display increased sensitivity to genotoxic stress. Nucleic Acids Research 2010, 38: 3595-604. PMID: 20110257, PMCID: PMC2887940, DOI: 10.1093/nar/gkq019.
- Prep1 (pKnox1)-deficiency leads to spontaneous tumor development in mice and accelerates EmuMyc lymphomagenesis: a tumor suppressor role for Prep1.Longobardi E, Iotti G, Di Rosa P, Mejetta S, Bianchi F, Fernandez-Diaz LC, Micali N, Nuciforo P, Lenti E, Ponzoni M, Doglioni C, Caniatti M, Di Fiore PP, Blasi F. Prep1 (pKnox1)-deficiency leads to spontaneous tumor development in mice and accelerates EmuMyc lymphomagenesis: a tumor suppressor role for Prep1. Molecular Oncology 2010, 4: 126-34. PMID: 20106730, PMCID: PMC5527898, DOI: 10.1016/j.molonc.2010.01.001.
- Prep1 directly regulates the intrinsic apoptotic pathway by controlling Bcl-XL levels.Micali N, Ferrai C, Fernandez-Diaz LC, Blasi F, Crippa MP. Prep1 directly regulates the intrinsic apoptotic pathway by controlling Bcl-XL levels. Molecular And Cellular Biology 2009, 29: 1143-51. PMID: 19103748, PMCID: PMC2643814, DOI: 10.1128/MCB.01273-08.
- Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype.Ferretti E, Villaescusa JC, Di Rosa P, Fernandez-Diaz LC, Longobardi E, Mazzieri R, Miccio A, Micali N, Selleri L, Ferrari G, Blasi F. Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype. Molecular And Cellular Biology 2006, 26: 5650-62. PMID: 16847320, PMCID: PMC1592771, DOI: 10.1128/MCB.00313-06.