James Leckman, MD, PhD
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Research Summary
Dr. Leckman is widely recognized as a master clinician with special skills in the evaluation and treatment of Tourette's syndrome (TS) and early onset obsessive-compulsive disorder (OCD). Since the early 1980s, he has seen and evaluated hundreds of individuals with these conditions. In 1999, he edited with Dr. Donald J. Cohen, Tourette's Syndrome: Tics, Obsessions, Compulsions - Developmental Psychopathology and Clinical Care, published by John Wiley & Sons. Given its success, this volume was re-issued in paperback in 2001. More recently, Dr. Leckman edited (along with Davide Martino) a 30-chapter volume, entitled, Tourette Syndrome published in 2014 by Oxford University Press. Dr. Leckman's specific research interests include the interaction of genes and environment in the pathogenesis of TS and OCD. His research on these disorders is well known and multifaceted from phenomenology and natural history, to neurobiology (neuroimaging, neuroendocrinology, neuroimmunology) to genetics, to risk factor research (perinatal factors are important), to treatment studies.
Specialized Terms: Child and adolescent psychiatry; Tourette's syndrome; Obsessive/compulsive disorder (OCD)
Extensive Research Description
James F. Leckman, M.D. is the Neison Harris Professor of Child Psychiatry, Psychiatry, Psychology and Pediatrics at Yale. He serves as the Director of Research for the Yale Child Study Center. Dr. Leckman is a well known child psychiatrist and patient-oriented clinical investigator. His peers have regularly selected him as one of the Best Doctors in America. Dr. Leckman is the author or co-author of over 450 original articles published in peer-reviewed journals, seven books, and 145 book chapters. In 2002, he was identified by American Society for Information, Science and Technology as a “Highly Cited Researcher” - one of the world's most cited authors in Psychology and Psychiatry – in the top half of the top one percent of all publishing researchers.
In 1999, he edited with Dr. Donald J. Cohen, Tourette's Syndrome: Tics, Obsessions, Compulsions - Developmental Psychopathology and Clinical Care, published by John Wiley & Sons. Given its success, this volume was re-issued in paper back in the fall of 2001. More recently, Dr. Leckman edited (along with Davide Martino) a 30-chapter volume, entitled, Tourette Syndrome published in 2014 by Oxford University Press.
Clinical expertise
Dr. Leckman is widely recognized as a committed clinician with special skills in the evaluation and treatment of Tourette’s syndrome (TS) and early onset obsessive-compulsive disorder (OCD). Since the early 1980s, he has seen and evaluated hundreds of individuals with these conditions. Physicians, patients and families from across the country and around the world regularly seek his advice. He is frequently invited to address professional, parent and advocacy groups at local, regional, and national meetings as well as international meetings. For example during the past four years, he has presented to professional and/or family groups in London, Rotterdam, Berlin, Rome, Johannesburg, Istanbul, Beirut, Sharm El Sheikh, Tehran, Tel Aviv, Taipei, Tokyo, Mexico City, Lima, and Sao Paulo. He is also a fully trained psychoanalyst.
Interdisciplinary research program on TS & OCD
One of Dr. Leckman’s main research interests has been the interaction of genes and environment in the pathogenesis of TS and OCD. His research on these disorders is well known and multifaceted from phenomenology and natural history, to neurobiology (neuroimaging, neuroendocrinology, neuroimmunology) to genetics, to risk factor research (perinatal factors are important), to treatment studies.
Formative Childhood and Peace Building
Most recently, in partnership with colleagues at UNICEF and the Mother-Child Education Foundation based in Turkey, Dr. Leckman has begun to explore the question whether strengthening families and enhancing child development is a path to peace and violence prevention. Related efforts include the Early Childhood Peace Consortium that was launched (September 2013) in New York in at the United Nations and the 15th Ernst Strüngmann Forum that took place in Frankfurt, Germany in October 2013. The deliberations of 40 international experts from a broad range of scientific disciplines are summarized in volume entitled, Formative Childhoods: The Transformative Power of Children and Families, published by the Massachusetts Institute of Technology Press in 2014. More information is available at: https://ecdpeace.org/work-content/revolutionary-volume-pathways-peace-transformative-power-children-families.
Coauthors
Research Interests
Adolescent Psychiatry; Child Psychiatry; Tourette Syndrome; Obsessive-Compulsive Disorder; Psychiatry; Tic Disorders; Global Health
Selected Publications
- Mispatterning and interneuron deficit in Tourette Syndrome basal ganglia organoidsBrady M, Mariani J, Koca Y, Szekely A, King R, Bloch M, Landeros-Weisenberger A, Leckman J, Vaccarino F. Mispatterning and interneuron deficit in Tourette Syndrome basal ganglia organoids Molecular Psychiatry 2022, 27: 5007-5019. PMID: 36447010, PMCID: PMC9949887, DOI: 10.1038/s41380-022-01880-5.
- TICS AND TOURETTE'S DISORDER: RECENT DEVELOPMENTS AND CLINICAL IMPLICATIONSAbi-Jaoude E, Leckman J. TICS AND TOURETTE'S DISORDER: RECENT DEVELOPMENTS AND CLINICAL IMPLICATIONS Journal Of The American Academy Of Child & Adolescent Psychiatry 2022, 61: s18-s19. DOI: 10.1016/j.jaac.2022.07.082.
- COMMUNICATION AND LANGUAGE DISORDERS IN CHILDREN AND ADOLESCENTSPetti T, Leckman J. COMMUNICATION AND LANGUAGE DISORDERS IN CHILDREN AND ADOLESCENTS Journal Of The American Academy Of Child & Adolescent Psychiatry 2022, 61: s136. DOI: 10.1016/j.jaac.2022.07.541.
- CAREGIVER RESILIENCE, PSYCHOPATHOLOGY, AND THE RELATION WITH SOCIAL-EMOTIONAL ADJUSTMENT OF YOUNG CHILDREN AFFECTED BY ARMED CONFLICT IN COLOMBIAJohnson I, Hein S, Ponguta L, Flores J, Tobón A, Larran J, Leckman J. CAREGIVER RESILIENCE, PSYCHOPATHOLOGY, AND THE RELATION WITH SOCIAL-EMOTIONAL ADJUSTMENT OF YOUNG CHILDREN AFFECTED BY ARMED CONFLICT IN COLOMBIA Journal Of The American Academy Of Child & Adolescent Psychiatry 2022, 61: s271. DOI: 10.1016/j.jaac.2022.09.411.
- A Functional Magnetic Resonance Imaging Study of Tic Suppression in Tourette SyndromePeterson B, Shudlarski P, Anderson A, Zhang H, Gatenby J, Lacadie C, Leckman J, Gore J. A Functional Magnetic Resonance Imaging Study of Tic Suppression in Tourette Syndrome 2022, 198-205. DOI: 10.4324/9780203822937-19.
- Course of Tic Severity in Tourette Syndrome: The First Two DecadesLeckman J, Zhang H, Vitale A, Lahnin F, Lynch K, Bondi C, Kim Y, Peterson B. Course of Tic Severity in Tourette Syndrome: The First Two Decades 2022, 80-85. DOI: 10.4324/9780203822937-8.
- Phenomenology of Tics and Sensory UrgesLeckman J, Bloch M, Sukhodolsky D, Artukoğlu B, Scahill L, King R. Phenomenology of Tics and Sensory Urges 2022, 6-25. DOI: 10.1093/med/9780197543214.003.0002.
- Social and Adaptive Functioning in Tourette SyndromeSukhodolsky D, Kalvin C, Artukoğlu B, Eicher V, Leckman J. Social and Adaptive Functioning in Tourette Syndrome 2022, 391-404. DOI: 10.1093/med/9780197543214.003.0023.
- The neurobiology of Gilles de la Tourette syndrome and chronic ticsLeckman J. The neurobiology of Gilles de la Tourette syndrome and chronic tics 2022, 3: 69-101. DOI: 10.1016/bs.irmvd.2021.11.005.
- Hats Off: Journal Awards 2021Novins D, Carlson G, Leckman J, Campo J, Towbin K. Hats Off: Journal Awards 2021 Journal Of The American Academy Of Child & Adolescent Psychiatry 2021, 60: 1539-1541. DOI: 10.1016/j.jaac.2021.10.001.
- Promoting Social Cohesion and Peacebuilding Through Investment in Early Childhood Development ProgramsDunne L, Brennan-Wilson A, Craig N, Miller S, Connolly P, Leckman J, Aber J, Yoshikawa H, Fitzpatrick S, Pham P, Vinck P, Walmsley P. Promoting Social Cohesion and Peacebuilding Through Investment in Early Childhood Development Programs 2021, 305-322. DOI: 10.1007/978-3-030-77688-6_17.
- Synaptic processes and immune-related pathways implicated in Tourette syndromeTsetsos F, Yu D, Sul JH, Huang AY, Illmann C, Osiecki L, Darrow SM, Hirschtritt ME, Greenberg E, Muller-Vahl KR, Stuhrmann M, Dion Y, Rouleau GA, Aschauer H, Stamenkovic M, Schlögelhofer M, Sandor P, Barr CL, Grados MA, Singer HS, Nöthen MM, Hebebrand J, Hinney A, King RA, Fernandez TV, Barta C, Tarnok Z, Nagy P, Depienne C, Worbe Y, Hartmann A, Budman CL, Rizzo R, Lyon GJ, McMahon WM, Batterson JR, Cath DC, Malaty IA, Okun MS, Berlin C, Woods DW, Lee PC, Jankovic J, Robertson MM, Gilbert DL, Brown LW, Coffey BJ, Dietrich A, Hoekstra PJ, Kuperman S, Zinner SH, Wagner M, Knowles JA, Jeremy Willsey A, Tischfield JA, Heiman GA, Cox NJ, Freimer NB, Neale BM, Davis LK, Coppola G, Mathews CA, Scharf JM, Paschou P, Barr C, Batterson J, Berlin C, Budman C, Cath D, Coppola G, Cox N, Darrow S, Davis L, Dion Y, Freimer N, Grados M, Greenberg E, Hirschtritt M, Huang A, Illmann C, King R, Kurlan R, Leckman J, Lyon G, Malaty I, Mathews C, McMahon W, Neale B, Okun M, Osiecki L, Robertson M, Rouleau G, Sandor P, Scharf J, Singer H, Smit J, Sul J, Yu D, Aschauer H, Barta C, Budman C, Cath D, Depienne C, Hartmann A, Hebebrand J, Konstantinidis A, Mathews C, Müller-Vahl K, Nagy P, Nöthen M, Paschou P, Rizzo R, Rouleau G, Sandor P, Scharf J, Schlögelhofer M, Stamenkovic M, Stuhrmann M, Tsetsos F, Tarnok Z, Wolanczyk T, Worbe Y, Brown L, Cheon K, Coffey B, Dietrich A, Fernandez T, Garcia-Delgar B, Gilbert D, Grice D, Hagstrøm J, Hedderly T, Heiman G, Heyman I, Hoekstra P, Huyser C, Kim Y, Kim Y, King R, Koh Y, Kook S, Kuperman S, Leventhal B, Madruga-Garrido M, Mir P, Morer A, Münchau A, Plessen K, Roessner V, Shin E, Song D, Song J, Tischfield J, Willsey A, Zinner S, Aschauer H, Barr C, Barta C, Batterson J, Berlin C, Brown L, Budman C, Cath D, Coffey B, Coppola G, Cox N, Darrow S, Davis L, Depienne C, Dietrich A, Dion Y, Fernandez T, Freimer N, Gilbert D, Grados M, Greenberg E, Hartmann A, Hebebrand J, Heiman G, Hirschtritt M, Hoekstra P, Huang A, Illmann C, Jankovic J, King R, Kuperman S, Lee P, Lyon G, Malaty I, Mathews C, McMahon W, Müller-Vahl K, Nagy P, Neale B, Nöthen M, Okun M, Osiecki L, Paschou P, Rizzo R, Robertson M, Rouleau G, Sandor P, Scharf J, Schlögelhofer M, Singer H, Stamenkovic M, Stuhrmann M, Sul J, Tarnok Z, Tischfield J, Tsetsos F, Willsey A, Woods D, Worbe Y, Yu D, Zinner S. Synaptic processes and immune-related pathways implicated in Tourette syndrome Translational Psychiatry 2021, 11: 56. PMID: 33462189, PMCID: PMC7814139, DOI: 10.1038/s41398-020-01082-z.
- 28.7 INTEGRATING CLINICAL AND RESEARCH TRAINING IN CHILD PSYCHIATRY: 15-YEAR OUTCOMES OF A FEDERALLY SUPPORTED PROGRAMCalhoun A, Bloch M, Stubbe D, Leckman J, Martin A. 28.7 INTEGRATING CLINICAL AND RESEARCH TRAINING IN CHILD PSYCHIATRY: 15-YEAR OUTCOMES OF A FEDERALLY SUPPORTED PROGRAM Journal Of The American Academy Of Child & Adolescent Psychiatry 2020, 59: s205. DOI: 10.1016/j.jaac.2020.08.252.
- OCD IN CHILDREN AND ADOLESCENTS: TREATMENT OUTCOMES, FAMILY PRESENTATION, AND PREDICTORS OF TREATMENT OUTCOMESThomsen P, Leckman J. OCD IN CHILDREN AND ADOLESCENTS: TREATMENT OUTCOMES, FAMILY PRESENTATION, AND PREDICTORS OF TREATMENT OUTCOMES Journal Of The American Academy Of Child & Adolescent Psychiatry 2020, 59: s301-s302. DOI: 10.1016/j.jaac.2020.07.686.
- Pathways to a more peaceful and sustainable world: The transformative power of children in familiesBritto PR, Hanöz-Penney S, Ponguta LA, Sunar D, Issa G, Hein SD, do Rosário MC, Almuneef MA, Korucu I, Togo Y, Kurbonov J, Choibekov N, Phan HTT, Fallon NS, Artukoğlu BB, Hartl FJ, Salah R, Fitzpatrick S, Connolly P, Dunne L, Miller S, Pruett K, Leckman JF. Pathways to a more peaceful and sustainable world: The transformative power of children in families Development And Psychopathology 2020, 33: 409-420. PMID: 32935656, DOI: 10.1017/s0954579420000681.
- Empiric Recurrence Risk Estimates for Chronic Tic Disorders: Implications for Genetic CounselingHeiman GA, Rispoli J, Seymour C, Leckman JF, King RA, Fernandez TV. Empiric Recurrence Risk Estimates for Chronic Tic Disorders: Implications for Genetic Counseling Frontiers In Neurology 2020, 11: 770. PMID: 32849224, PMCID: PMC7432137, DOI: 10.3389/fneur.2020.00770.
- Manifesto for new directions in developmental scienceBarbot B, Hein S, Trentacosta C, Beckmann JF, Bick J, Crocetti E, Liu Y, Rao SF, Liew J, Overbeek G, Ponguta LA, Scheithauer H, Super C, Arnett J, Bukowski W, Cook TD, Côté J, Eccles JS, Eid M, Hiraki K, Johnson M, Juang L, Landi N, Leckman J, McCardle P, Mulvey KL, Piquero AR, Preiss DD, Siegler R, Soenens B, Yousafzai AK, Bornstein MH, Cooper CR, Goossens L, Harkness S, IJzendoorn M. Manifesto for new directions in developmental science New Directions For Child And Adolescent Development 2020, 2020: 135-149. PMID: 32960503, DOI: 10.1002/cad.20359.
- An examination of the relationship between regulatory T cells and symptom flare-ups in children and adolescents diagnosed with chronic tic disorder and Tourette syndromeYildirim Z, Karabekiroglu K, Yildiran A, Celiksoy MH, Artukoglu B, Baykal S, Babadağı Z, Leckman J. An examination of the relationship between regulatory T cells and symptom flare-ups in children and adolescents diagnosed with chronic tic disorder and Tourette syndrome Nordic Journal Of Psychiatry 2020, 75: 18-24. PMID: 32580599, DOI: 10.1080/08039488.2020.1779808.
- Autoantibody Biomarkers for Basal Ganglia Encephalitis in Sydenham Chorea and Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal InfectionsChain JL, Alvarez K, Mascaro-Blanco A, Reim S, Bentley R, Hommer R, Grant P, Leckman JF, Kawikova I, Williams K, Stoner JA, Swedo SE, Cunningham MW. Autoantibody Biomarkers for Basal Ganglia Encephalitis in Sydenham Chorea and Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infections Frontiers In Psychiatry 2020, 11: 564. PMID: 32670106, PMCID: PMC7328706, DOI: 10.3389/fpsyt.2020.00564.
- Antibodies From Children With PANDAS Bind Specifically to Striatal Cholinergic Interneurons and Alter Their ActivityXu J, Liu RJ, Fahey S, Frick L, Leckman J, Vaccarino F, Duman RS, Williams K, Swedo S, Pittenger C. Antibodies From Children With PANDAS Bind Specifically to Striatal Cholinergic Interneurons and Alter Their Activity American Journal Of Psychiatry 2020, 178: 48-64. PMID: 32539528, PMCID: PMC8573771, DOI: 10.1176/appi.ajp.2020.19070698.
- Effects of the Global Coronavirus Disease-2019 Pandemic on Early Childhood Development: Short- and Long-Term Risks and Mitigating Program and Policy ActionsYoshikawa H, Wuermli AJ, Britto PR, Dreyer B, Leckman JF, Lye SJ, Ponguta LA, Richter LM, Stein A. Effects of the Global Coronavirus Disease-2019 Pandemic on Early Childhood Development: Short- and Long-Term Risks and Mitigating Program and Policy Actions The Journal Of Pediatrics 2020, 223: 188-193. PMID: 32439312, PMCID: PMC7234941, DOI: 10.1016/j.jpeds.2020.05.020.
- Integrating clinical and research training in child psychiatry: fifteen-year outcomes of a federally supported programCalhoun A, Bloch MH, Stubbe D, Leckman JF, Martin A. Integrating clinical and research training in child psychiatry: fifteen-year outcomes of a federally supported program Child And Adolescent Psychiatry And Mental Health 2020, 14: 21. PMID: 32467724, PMCID: PMC7227282, DOI: 10.1186/s13034-020-00328-4.
- The prevalence of behavioral and emotional problems among Chinese school children and adolescents aged 6–16: a national surveyCui Y, Li F, Leckman JF, Guo L, Ke X, Liu J, Zheng Y, Li Y. The prevalence of behavioral and emotional problems among Chinese school children and adolescents aged 6–16: a national survey European Child & Adolescent Psychiatry 2020, 30: 233-241. PMID: 32172341, DOI: 10.1007/s00787-020-01507-6.
- Maternal perceptions of father involvement among refugee and disadvantaged families in Beirut, LebanonHein S, Bick J, Issa G, Aoude L, Maalouf C, Awar A, Nourallah S, Zonderman AL, Householder S, Katsovich L, Khoshnood K, Moore C, Salah R, Britto PR, Leckman JF, Ponguta LA. Maternal perceptions of father involvement among refugee and disadvantaged families in Beirut, Lebanon PLOS ONE 2020, 15: e0229670. PMID: 32134961, PMCID: PMC7058288, DOI: 10.1371/journal.pone.0229670.
- An integrated program of computer-presented and physical cognitive training exercises for children with attention-deficit/hyperactivity disorderWexler BE, Vitulano LA, Moore C, Katsovich L, Smith SD, Rush C, Grantz H, Dong J, Leckman JF. An integrated program of computer-presented and physical cognitive training exercises for children with attention-deficit/hyperactivity disorder Psychological Medicine 2020, 51: 1524-1535. PMID: 32090720, DOI: 10.1017/s0033291720000288.
- Risk factors for obsessive–compulsive symptoms. Follow-up of a community-based youth cohortMacul Ferreira de Barros P, do Rosário MC, Szejko N, Polga N, Requena GL, Ravagnani B, Fatori D, Batistuzzo MC, Hoexter MQ, Rohde LA, Polanczyk GV, Leckman JF, Miguel EC, de Alvarenga PG. Risk factors for obsessive–compulsive symptoms. Follow-up of a community-based youth cohort European Child & Adolescent Psychiatry 2020, 30: 89-104. PMID: 32076869, DOI: 10.1007/s00787-020-01495-7.
- Effects of the Mother-Child Education Program on Parenting Stress and Disciplinary Practices Among Refugee and Other Marginalized Communities in Lebanon: A Pilot Randomized Controlled TrialPonguta LA, Issa G, Aoudeh L, Maalouf C, Hein SD, Zonderman AL, Katsovich L, Khoshnood K, Bick J, Awar A, Nourallah S, Householder S, Moore CC, Salah R, Britto PR, Leckman JF. Effects of the Mother-Child Education Program on Parenting Stress and Disciplinary Practices Among Refugee and Other Marginalized Communities in Lebanon: A Pilot Randomized Controlled Trial Journal Of The American Academy Of Child & Adolescent Psychiatry 2020, 59: 727-738. PMID: 32014538, DOI: 10.1016/j.jaac.2019.12.010.
- Kundalini Yoga Meditation Versus the Relaxation Response Meditation for Treating Adults With Obsessive-Compulsive Disorder: A Randomized Clinical TrialShannahoff-Khalsa D, Fernandes RY, de B. Pereira C, March JS, Leckman JF, Golshan S, Vieira MSR, Polanczyk GV, Miguel EC, Shavitt RG. Kundalini Yoga Meditation Versus the Relaxation Response Meditation for Treating Adults With Obsessive-Compulsive Disorder: A Randomized Clinical Trial Frontiers In Psychiatry 2019, 10: 793. PMID: 31780963, PMCID: PMC6859828, DOI: 10.3389/fpsyt.2019.00793.
- TOWARDS AN IMMUNE (INFLAMMATION)-MEDIATED SUBTYPE OF ASDThom R, McDougle C, Leckman J. TOWARDS AN IMMUNE (INFLAMMATION)-MEDIATED SUBTYPE OF ASD Journal Of The American Academy Of Child & Adolescent Psychiatry 2019, 58: s102. DOI: 10.1016/j.jaac.2019.07.540.
- Implementation Evaluation of the Mother‐Child Education Program Among Refugee and Other Vulnerable Communities in LebanonPonguta LA, Issa G, Aoudeh L, Maalouf C, Nourallah S, Khoshnood K, Zonderman AL, Katsovich L, Moore C, Salah R, Al‐Soleiti M, Britto PR, Leckman JF. Implementation Evaluation of the Mother‐Child Education Program Among Refugee and Other Vulnerable Communities in Lebanon New Directions For Child And Adolescent Development 2019, 2019: 91-116. PMID: 31509332, DOI: 10.1002/cad.20314.
- What does immunology have to do with brain development and neuropsychiatric disorders?Leckman J, Alvarenga P, Ravagnani B, Johnson I. What does immunology have to do with brain development and neuropsychiatric disorders? Revista De Medicina 2019, 98: 241-253. DOI: 10.11606/issn.1679-9836.v98i4p241-253.
- Randomized, Sham-Controlled Trial of Real-Time Functional Magnetic Resonance Imaging Neurofeedback for Tics in Adolescents With Tourette SyndromeSukhodolsky DG, Walsh C, Koller WN, Eilbott J, Rance M, Fulbright RK, Zhao Z, Bloch MH, King R, Leckman JF, Scheinost D, Pittman B, Hampson M. Randomized, Sham-Controlled Trial of Real-Time Functional Magnetic Resonance Imaging Neurofeedback for Tics in Adolescents With Tourette Syndrome Biological Psychiatry 2019, 87: 1063-1070. PMID: 31668476, PMCID: PMC7015800, DOI: 10.1016/j.biopsych.2019.07.035.
- Effects of Integrated Brain, Body, and Social (IBBS) intervention on ERP measures of attentional control in children with ADHDSmith SD, Crowley MJ, Ferrey A, Ramsey K, Wexler BE, Leckman JF, Sukhodolsky DG. Effects of Integrated Brain, Body, and Social (IBBS) intervention on ERP measures of attentional control in children with ADHD Psychiatry Research 2019, 278: 248-257. PMID: 31233935, PMCID: PMC6637759, DOI: 10.1016/j.psychres.2019.06.021.
- Pathways to Wellbeing and a More Peaceful and Sustainable World: The Transformative Power of Children and FamiliesLECKMAN J, DONALDSON C, AFFOLTER F, PONGUTA L. Pathways to Wellbeing and a More Peaceful and Sustainable World: The Transformative Power of Children and Families 児童青年精神医学とその近接領域 2019, 60: 278-298. DOI: 10.20615/jscap.60.3_278.
- Not just in Philadelphia – But across the globeLeckman JF, Rubinstein J. Not just in Philadelphia – But across the globe Depression And Anxiety 2019, 36: 584-585. PMID: 31099452, DOI: 10.1002/da.22905.
- F36. Obsessive-Compulsive symptoms, Polygenic Risk Score and Thalamic Development in Children From the Brazilian High-Risk Cohort StudyRavagnani B, Hoexter M, Santoro M, Leckman J, Pan P, Salum G, Jackowski A, Hampson M, do Rosário M, Belangero S, Alvarenga P, de Barros P, Miguel E, Zugman A. F36. Obsessive-Compulsive symptoms, Polygenic Risk Score and Thalamic Development in Children From the Brazilian High-Risk Cohort Study Biological Psychiatry 2019, 85: s226. DOI: 10.1016/j.biopsych.2019.03.573.
- The impact of attention deficit hyperactivity disorder in obsessive‐compulsive disorder subjectsBlanco‐Vieira T, Santos M, Ferrão YA, Torres AR, Miguel EC, Bloch MH, Leckman JF, do Rosario MC. The impact of attention deficit hyperactivity disorder in obsessive‐compulsive disorder subjects Depression And Anxiety 2019, 36: 533-542. PMID: 30990937, DOI: 10.1002/da.22898.
- Oxytocin Enhances the Neural Efficiency of Social PerceptionTillman R, Gordon I, Naples A, Rolison M, Leckman JF, Feldman R, Pelphrey KA, McPartland JC. Oxytocin Enhances the Neural Efficiency of Social Perception Frontiers In Human Neuroscience 2019, 13: 71. PMID: 30914935, PMCID: PMC6421852, DOI: 10.3389/fnhum.2019.00071.
- Obsessive-Compulsive Symptomatology in Community Youth: Typical Development or a Red Flag for Psychopathology?Barzilay R, Patrick A, Calkins ME, Moore TM, Wolf DH, Benton TD, Leckman JF, Gur RC, Gur RE. Obsessive-Compulsive Symptomatology in Community Youth: Typical Development or a Red Flag for Psychopathology? Journal Of The American Academy Of Child & Adolescent Psychiatry 2018, 58: 277-286.e4. PMID: 30738554, DOI: 10.1016/j.jaac.2018.06.038.
- Early Childhood Development Programs, Peacebuilding, and the Sustainable Development Goals: Opportunities for Interdisciplinary Research and Multisectoral PartnershipsAngelica Ponguta L, Donaldson C, Affolter F, Connolly P, Dunne L, Miller S, Britto P, Salah R, Leckman J. Early Childhood Development Programs, Peacebuilding, and the Sustainable Development Goals: Opportunities for Interdisciplinary Research and Multisectoral Partnerships 2018, 74: 77-95. DOI: 10.1007/978-3-319-96592-5_4.
- 2.57 ADHD Treatments for Children: Parent PerspectivesVitulano L, Saunders D, Kober H, Mitchell J, Davis N, Leckman J, Vitulano M, Goodhue B, Artukoglu B. 2.57 ADHD Treatments for Children: Parent Perspectives Journal Of The American Academy Of Child & Adolescent Psychiatry 2018, 57: s177. DOI: 10.1016/j.jaac.2018.09.144.
- 38.3 Reliability and Revision of the Yale Global Tic Severity ScaleMcGuire J, Leckman J, Scahill L. 38.3 Reliability and Revision of the Yale Global Tic Severity Scale Journal Of The American Academy Of Child & Adolescent Psychiatry 2018, 57: s56. DOI: 10.1016/j.jaac.2018.07.236.
- De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in PathogenesisWang S, Mandell JD, Kumar Y, Sun N, Morris MT, Arbelaez J, Nasello C, Dong S, Duhn C, Zhao X, Yang Z, Padmanabhuni SS, Yu D, King RA, Dietrich A, Khalifa N, Dahl N, Huang AY, Neale BM, Coppola G, Mathews CA, Scharf JM, Study T, Abdulkadir M, Arbelaez J, Bodmer B, Bromberg Y, Brown L, Cheon K, Coffey B, Deng L, Dietrich A, Dong S, Duhn C, Elzerman L, Fernandez T, Fremer C, Garcia-Delgar B, Gilbert D, Grice D, Hagstrøm J, Hedderly T, Heiman G, Heyman I, Hoekstra P, Hong H, Huyser C, Kim E, Kim Y, Kim Y, King R, Koh Y, Kook S, Kuperman S, Leventhal B, Ludolph A, Madruga-Garrido M, Mandell J, Maras A, Mir P, Morer A, Morris M, Müller-Vahl K, Münchau A, Murphy T, Nasello C, Plessen K, Poisner H, Roessner V, Sanders S, Shin E, Song D, Song J, State M, Sun N, Thackray J, Tischfield J, Tübing J, Visscher F, Wanderer S, Wang S, Willsey A, Woods M, Xing J, Zhang Y, Zhao X, Zinner S, Initiative T, Androutsos C, Barta C, Farkas L, Fichna J, Georgitsi M, Janik P, Karagiannidis I, Koumoula A, Nagy P, Paschou P, Puchala J, Rizzo R, Szejko N, Szymanska U, Tarnok Z, Tsironi V, Wolanczyk T, Zekanowski C, Genetics T, Barr C, Batterson J, Berlin C, Bruun R, Budman C, Cath D, Chouinard S, Coppola G, Cox N, Darrow S, Davis L, Dion Y, Freimer N, Grados M, Hirschtritt M, Huang A, Illmann C, Kurlan R, Leckman J, Lyon G, Malaty I, Mathews C, MacMahon W, Neale B, Okun M, Osiecki L, Pauls D, Posthuma D, Ramensky V, Robertson M, Rouleau G, Sandor P, Scharf J, Singer H, Smit J, Sul J, Yu D, Fernandez T, Buxbaum J, De Rubeis S, Grice D, Xing J, Heiman G, Tischfield J, Paschou P, Willsey A, State M. De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in Pathogenesis Cell Reports 2018, 24: 3441-3454.e12. PMID: 30257206, PMCID: PMC6475626, DOI: 10.1016/j.celrep.2018.08.082.
- Adaptive treatment strategies for children and adolescents with Obsessive-Compulsive Disorder: A sequential multiple assignment randomized trialFatori D, de Bragança Pereira CA, Asbahr FR, Requena G, Alvarenga PG, de Mathis MA, Rohde LA, Leckman JF, March JS, Polanczyk GV, Miguel EC, Shavitt RG. Adaptive treatment strategies for children and adolescents with Obsessive-Compulsive Disorder: A sequential multiple assignment randomized trial Journal Of Anxiety Disorders 2018, 58: 42-50. PMID: 30025255, DOI: 10.1016/j.janxdis.2018.07.002.
- A multicenter examination and strategic revisions of the Yale Global Tic Severity ScaleMcGuire JF, Piacentini J, Storch EA, Murphy TK, Ricketts EJ, Woods DW, Walkup JW, Peterson AL, Wilhelm S, Lewin AB, McCracken JT, Leckman JF, Scahill L. A multicenter examination and strategic revisions of the Yale Global Tic Severity Scale Neurology 2018, 90: e1711-e1719. PMID: 29653992, PMCID: PMC5952973, DOI: 10.1212/wnl.0000000000005474.
- Attention and executive functions computer training for attention-deficit/hyperactivity disorder (ADHD): results from a randomized, controlled trialBikic A, Leckman JF, Christensen TØ, Bilenberg N, Dalsgaard S. Attention and executive functions computer training for attention-deficit/hyperactivity disorder (ADHD): results from a randomized, controlled trial European Child & Adolescent Psychiatry 2018, 27: 1563-1574. PMID: 29644473, DOI: 10.1007/s00787-018-1151-y.
- Steps Toward Peace and Violence Prevention Across Generations: The Potential of Early Child Development in the Context of the 2030 Sustainable Development GoalsLeckman JF, Britto PR. Steps Toward Peace and Violence Prevention Across Generations: The Potential of Early Child Development in the Context of the 2030 Sustainable Development Goals New Directions For Child And Adolescent Development 2018, 2018: 5-12. PMID: 29537184, DOI: 10.1002/cad.20227.
- Efficacy and Safety of Deep Brain Stimulation in Tourette Syndrome: The International Tourette Syndrome Deep Brain Stimulation Public Database and RegistryMartinez-Ramirez D, Jimenez-Shahed J, Leckman JF, Porta M, Servello D, Meng FG, Kuhn J, Huys D, Baldermann JC, Foltynie T, Hariz MI, Joyce EM, Zrinzo L, Kefalopoulou Z, Silburn P, Coyne T, Mogilner AY, Pourfar MH, Khandhar SM, Auyeung M, Ostrem JL, Visser-Vandewalle V, Welter ML, Mallet L, Karachi C, Houeto JL, Klassen BT, Ackermans L, Kaido T, Temel Y, Gross RE, Walker HC, Lozano AM, Walter BL, Mari Z, Anderson WS, Changizi BK, Moro E, Zauber SE, Schrock LE, Zhang JG, Hu W, Rizer K, Monari EH, Foote KD, Malaty IA, Deeb W, Gunduz A, Okun MS. Efficacy and Safety of Deep Brain Stimulation in Tourette Syndrome: The International Tourette Syndrome Deep Brain Stimulation Public Database and Registry JAMA Neurology 2018, 75: 353-359. PMID: 29340590, PMCID: PMC5885852, DOI: 10.1001/jamaneurol.2017.4317.
- DNA methylome variation in a perinatal nurse-visitation program that reduces child maltreatment: a 27-year follow-upO’Donnell K, Chen L, MacIsaac JL, McEwen LM, Nguyen T, Beckmann K, Zhu Y, Chen LM, Brooks-Gunn J, Goldman D, Grigorenko EL, Leckman JF, Diorio J, Karnani N, Olds DL, Holbrook JD, Kobor MS, Meaney MJ. DNA methylome variation in a perinatal nurse-visitation program that reduces child maltreatment: a 27-year follow-up Translational Psychiatry 2018, 8: 15. PMID: 29317599, PMCID: PMC5802588, DOI: 10.1038/s41398-017-0063-9.
- Chapter 49 Genetic susceptibility in obsessive-compulsive disorderFernandez TV, Leckman JF, Pittenger C. Chapter 49 Genetic susceptibility in obsessive-compulsive disorder 2018, 148: 767-781. PMID: 29478613, DOI: 10.1016/b978-0-444-64076-5.00049-1.
- Differential binding of antibodies in PANDAS patients to cholinergic interneurons in the striatumFrick L, Rapanelli M, Jindachomthong K, Grant P, Leckman JF, Swedo S, Williams K, Pittenger C. Differential binding of antibodies in PANDAS patients to cholinergic interneurons in the striatum Brain Behavior And Immunity 2017, 69: 304-311. PMID: 29233751, PMCID: PMC5857467, DOI: 10.1016/j.bbi.2017.12.004.
- 6. A Biobehavioral Model of Attachment and BondingLeckman J, Hrdy S, Keverne E, Carter C. 6. A Biobehavioral Model of Attachment and Bonding 2017, 116-146. DOI: 10.12987/9780300159318-007.
- A total-population multigenerational family clustering study of autoimmune diseases in obsessive–compulsive disorder and Tourette’s/chronic tic disordersMataix-Cols D, Frans E, Pérez-Vigil A, Kuja-Halkola R, Gromark C, Isomura K, Fernández de la Cruz L, Serlachius E, Leckman JF, Crowley JJ, Rück C, Almqvist C, Lichtenstein P, Larsson H. A total-population multigenerational family clustering study of autoimmune diseases in obsessive–compulsive disorder and Tourette’s/chronic tic disorders Molecular Psychiatry 2017, 23: 1652-1658. PMID: 29133949, PMCID: PMC5951741, DOI: 10.1038/mp.2017.215.
- Longitudinal outcomes of children with pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS)Leon J, Hommer R, Grant P, Farmer C, D’Souza P, Kessler R, Williams K, Leckman JF, Swedo S. Longitudinal outcomes of children with pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS) European Child & Adolescent Psychiatry 2017, 27: 637-643. PMID: 29119300, DOI: 10.1007/s00787-017-1077-9.
- What Are the Transgenerational Consequences of Maternal Childhood Adversity and Maternal Stress During Pregnancy?Leckman JF. What Are the Transgenerational Consequences of Maternal Childhood Adversity and Maternal Stress During Pregnancy? Journal Of The American Academy Of Child & Adolescent Psychiatry 2017, 56: 914-915. PMID: 29096770, DOI: 10.1016/j.jaac.2017.09.421.
- Clinical Management of Pediatric Acute-Onset Neuropsychiatric Syndrome: Part I—Psychiatric and Behavioral InterventionsThienemann M, Murphy T, Leckman J, Shaw R, Williams K, Kapphahn C, Frankovich J, Geller D, Bernstein G, Chang K, Elia J, Swedo S. Clinical Management of Pediatric Acute-Onset Neuropsychiatric Syndrome: Part I—Psychiatric and Behavioral Interventions Journal Of Child And Adolescent Psychopharmacology 2017, 27: 566-573. PMID: 28722481, PMCID: PMC5610394, DOI: 10.1089/cap.2016.0145.
- Risk of Irritability With Psychostimulant Treatment in Children With ADHD: A Meta-Analysis.Stuckelman ZD, Mulqueen JM, Ferracioli-Oda E, Cohen SC, Coughlin CG, Leckman JF, Bloch MH. Risk of Irritability With Psychostimulant Treatment in Children With ADHD: A Meta-Analysis. The Journal Of Clinical Psychiatry 2017, 78: e648-e655. PMID: 28682529, DOI: 10.4088/jcp.15r10601.
- A double-blind randomized pilot trial comparing computerized cognitive exercises to Tetris in adolescents with attention-deficit/hyperactivity disorderBikic A, Christensen TØ, Leckman JF, Bilenberg N, Dalsgaard S. A double-blind randomized pilot trial comparing computerized cognitive exercises to Tetris in adolescents with attention-deficit/hyperactivity disorder Nordic Journal Of Psychiatry 2017, 71: 455-464. PMID: 28598701, DOI: 10.1080/08039488.2017.1328070.
- De Novo Coding Variants Are Strongly Associated with Tourette DisorderWillsey AJ, Fernandez TV, Yu D, King RA, Dietrich A, Xing J, Sanders SJ, Mandell JD, Huang AY, Richer P, Smith L, Dong S, Samocha KE, Genetics T, Abdulkadir M, Bohnenpoll J, Bromberg Y, Brown L, Cheon K, Coffey B, Deng L, Dietrich A, Dong S, Elzerman L, Fernandez T, Fründt O, Garcia-Delgar B, Gedvilaite E, Gilbert D, Grice D, Hagstrøm J, Hedderly T, Heiman G, Heyman I, Hoekstra P, Hong H, Huyser C, Ibanez-Gomez L, Kim Y, Kim Y, King R, Koh Y, Kook S, Kuperman S, Lamerz A, Leventhal B, Ludolph A, da Silva C, Madruga-Garrido M, Mandell J, Maras A, Mir P, Morer A, Münchau A, Murphy T, Nasello C, Openneer T, Plessen K, Richer P, Roessner V, Sanders S, Shin E, Sival D, Smith L, Song D, Song J, State M, Stolte A, Sun N, Tischfield J, Tübing J, Visscher F, Walker M, Wanderer S, Wang S, Willsey A, Woods M, Xing J, Zhang Y, Zhou A, Zinner S, Genetics T, Barr C, Batterson J, Berlin C, Bruun R, Budman C, Cath D, Chouinard S, Coppola G, Cox N, Darrow S, Davis L, Dion Y, Freimer N, Grados M, Hirschtritt M, Huang A, Illmann C, Kurlan R, Leckman J, Lyon G, Malaty I, Mathews C, MaMahon W, Neale B, Okun M, Osiecki L, Pauls D, Posthuma D, Ramensky V, Robertson M, Rouleau G, Sandor P, Scharf J, Singer H, Smit J, Sul J, Yu D, Neale B, Coppola G, Mathews C, Tischfield J, Scharf J, State M, Heiman G. De Novo Coding Variants Are Strongly Associated with Tourette Disorder Neuron 2017, 94: 486-499.e9. PMID: 28472652, PMCID: PMC5769876, DOI: 10.1016/j.neuron.2017.04.024.
- Mortality risk in a nationwide cohort of individuals with tic disorders and with tourette syndromeMeier SM, Dalsgaard S, Mortensen PB, Leckman JF, Plessen KJ. Mortality risk in a nationwide cohort of individuals with tic disorders and with tourette syndrome Movement Disorders 2017, 32: 605-609. PMID: 28339122, DOI: 10.1002/mds.26939.
- The Child Behavior Checklist—Obsessive-Compulsive Subscale Detects Severe Psychopathology and Behavioral Problems Among School-Aged ChildrenSaad LO, do Rosario MC, Cesar RC, Batistuzzo MC, Hoexter MQ, Manfro GG, Shavitt RG, Leckman JF, Miguel EC, Alvarenga PG. The Child Behavior Checklist—Obsessive-Compulsive Subscale Detects Severe Psychopathology and Behavioral Problems Among School-Aged Children Journal Of Child And Adolescent Psychopharmacology 2017, 27: 342-348. PMID: 28151703, PMCID: PMC5439443, DOI: 10.1089/cap.2016.0125.
- Gilles de la Tourette syndromeRobertson MM, Eapen V, Singer HS, Martino D, Scharf JM, Paschou P, Roessner V, Woods DW, Hariz M, Mathews CA, Črnčec R, Leckman JF. Gilles de la Tourette syndrome Nature Reviews Disease Primers 2017, 3: 16097. PMID: 28150698, DOI: 10.1038/nrdp.2016.97.
- Temporal Association of Certain Neuropsychiatric Disorders Following Vaccination of Children and Adolescents: A Pilot Case–Control StudyLeslie DL, Kobre RA, Richmand BJ, Guloksuz S, Leckman JF. Temporal Association of Certain Neuropsychiatric Disorders Following Vaccination of Children and Adolescents: A Pilot Case–Control Study Frontiers In Psychiatry 2017, 8: 3. PMID: 28154539, PMCID: PMC5244035, DOI: 10.3389/fpsyt.2017.00003.
- Elevated plasma concentrations of S100 calcium-binding protein B and tumor necrosis factor alpha in children with autism spectrum disordersGuloksuz SA, Abali O, Cetin E, Gazioglu S, Deniz G, Yildirim A, Kawikova I, Guloksuz S, Leckman JF. Elevated plasma concentrations of S100 calcium-binding protein B and tumor necrosis factor alpha in children with autism spectrum disorders Brazilian Journal Of Psychiatry 2017, 39: 195-200. PMID: 28099628, PMCID: PMC7111377, DOI: 10.1590/1516-4446-2015-1843.
- Systematic review of severity scales and screening instruments for tics: Critique and recommendationsMartino D, Pringsheim TM, Cavanna AE, Colosimo C, Hartmann A, Leckman JF, Luo S, Munchau A, Goetz CG, Stebbins GT, Martinez‐Martin P, Development T. Systematic review of severity scales and screening instruments for tics: Critique and recommendations Movement Disorders 2017, 32: 467-473. PMID: 28071825, PMCID: PMC5482361, DOI: 10.1002/mds.26891.
- Oxytocin response to youth–mother interactions in clinically anxious youth is associated with separation anxiety and dyadic behaviorLebowitz ER, Silverman WK, Martino AM, Zagoory‐Sharon O, Feldman R, Leckman JF. Oxytocin response to youth–mother interactions in clinically anxious youth is associated with separation anxiety and dyadic behavior Depression And Anxiety 2017, 34: 127-136. PMID: 28052452, PMCID: PMC5503301, DOI: 10.1002/da.22585.
- Tics and Tourette SyndromeSukhodolsky D, Gladstone T, Kaushal S, Piasecka J, Leckman J. Tics and Tourette Syndrome 2017, 241-256. DOI: 10.1007/978-3-319-71210-9_14.
- A preliminary study of movement intensity during a Go/No-Go task and its association with ADHD outcomes and symptom severityLi F, Zheng Y, Smith SD, Shic F, Moore CC, Zheng X, Qi Y, Liu Z, Leckman JF. A preliminary study of movement intensity during a Go/No-Go task and its association with ADHD outcomes and symptom severity Child And Adolescent Psychiatry And Mental Health 2016, 10: 47. PMID: 27999615, PMCID: PMC5153899, DOI: 10.1186/s13034-016-0135-2.
- Intranasal Oxytocin Enhances Connectivity in the Neural Circuitry Supporting Social Motivation and Social Perception in Children with AutismGordon I, Jack A, Pretzsch CM, Vander Wyk B, Leckman JF, Feldman R, Pelphrey KA. Intranasal Oxytocin Enhances Connectivity in the Neural Circuitry Supporting Social Motivation and Social Perception in Children with Autism Scientific Reports 2016, 6: 35054. PMID: 27845765, PMCID: PMC5109935, DOI: 10.1038/srep35054.
- Prenatal and Perinatal Risk Factors and the Promise of Birth Cohort Studies: Origins of Obsessive-Compulsive DisorderFernandez TV, Leckman JF. Prenatal and Perinatal Risk Factors and the Promise of Birth Cohort Studies: Origins of Obsessive-Compulsive Disorder JAMA Psychiatry 2016, 73: 1117-1118. PMID: 27706471, PMCID: PMC5180419, DOI: 10.1001/jamapsychiatry.2016.2092.
- Nurturing care: promoting early childhood developmentBritto PR, Lye SJ, Proulx K, Yousafzai AK, Matthews SG, Vaivada T, Perez-Escamilla R, Rao N, Ip P, Fernald LCH, MacMillan H, Hanson M, Wachs TD, Yao H, Yoshikawa H, Cerezo A, Leckman JF, Bhutta ZA, Group F. Nurturing care: promoting early childhood development The Lancet 2016, 389: 91-102. PMID: 27717615, DOI: 10.1016/s0140-6736(16)31390-3.
- The Origins of Tourette Syndrome: Prenatal Risk Factors and the Promise of Birth Cohort StudiesLeckman JF, Fernandez TV. The Origins of Tourette Syndrome: Prenatal Risk Factors and the Promise of Birth Cohort Studies Journal Of The American Academy Of Child & Adolescent Psychiatry 2016, 55: 751-753. PMID: 27566115, PMCID: PMC5180440, DOI: 10.1016/j.jaac.2016.06.009.
- Randomized, Controlled Trial of Intravenous Immunoglobulin for Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal InfectionsWilliams KA, Swedo SE, Farmer CA, Grantz H, Grant PJ, D’Souza P, Hommer R, Katsovich L, King RA, Leckman JF. Randomized, Controlled Trial of Intravenous Immunoglobulin for Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections Journal Of The American Academy Of Child & Adolescent Psychiatry 2016, 55: 860-867.e2. PMID: 27663941, DOI: 10.1016/j.jaac.2016.06.017.
- Rapid Eye Movement Sleep Abnormalities in Children with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS).Gaughan T, Buckley A, Hommer R, Grant P, Williams K, Leckman JF, Swedo SE. Rapid Eye Movement Sleep Abnormalities in Children with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS). Journal Of Clinical Sleep Medicine 2016, 12: 1027-32. PMID: 27166296, PMCID: PMC4918985, DOI: 10.5664/jcsm.5942.
- A Randomized Controlled Trial of an Integrated Brain, Body, and Social Intervention for Children With ADHDSmith SD, Vitulano LA, Katsovich L, Li S, Moore C, Li F, Grantz H, Zheng X, Eicher V, Guloksuz S, Zheng Y, Dong J, Sukhodolsky DG, Leckman JF. A Randomized Controlled Trial of an Integrated Brain, Body, and Social Intervention for Children With ADHD Journal Of Attention Disorders 2016, 24: 780-794. PMID: 27178060, PMCID: PMC5107355, DOI: 10.1177/1087054716647490.
- Cross-generational influences on childhood anxiety disorders: pathways and mechanismsLebowitz ER, Leckman JF, Silverman WK, Feldman R. Cross-generational influences on childhood anxiety disorders: pathways and mechanisms Journal Of Neural Transmission 2016, 123: 1053-1067. PMID: 27145763, PMCID: PMC5007197, DOI: 10.1007/s00702-016-1565-y.
- N-Acetylcysteine in the Treatment of Pediatric Tourette Syndrome: Randomized, Double-Blind, Placebo-Controlled Add-On TrialBloch MH, Panza KE, Yaffa A, Alvarenga PG, Jakubovski E, Mulqueen JM, Landeros-Weisenberger A, Leckman JF. N-Acetylcysteine in the Treatment of Pediatric Tourette Syndrome: Randomized, Double-Blind, Placebo-Controlled Add-On Trial Journal Of Child And Adolescent Psychopharmacology 2016, 26: 327-334. PMID: 27027204, PMCID: PMC6445198, DOI: 10.1089/cap.2015.0109.
- Deep Brain Stimulation for Tourette Syndrome: Lessons Learned and Future DirectionsLeckman JF. Deep Brain Stimulation for Tourette Syndrome: Lessons Learned and Future Directions Biological Psychiatry 2016, 79: 343-344. PMID: 26847660, DOI: 10.1016/j.biopsych.2015.11.028.
- Understanding the covariation of tics, attention‐deficit/hyperactivity, and obsessive‐compulsive symptoms: A population‐based adult twin studyPinto R, Monzani B, Leckman JF, Rück C, Serlachius E, Lichtenstein P, Mataix‐Cols D. Understanding the covariation of tics, attention‐deficit/hyperactivity, and obsessive‐compulsive symptoms: A population‐based adult twin study American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2016, 171: 938-947. PMID: 26919823, DOI: 10.1002/ajmg.b.32436.
- Understanding Developmental Psychopathology: How Useful Are Evolutionary Perspectives?Leckman J. Understanding Developmental Psychopathology: How Useful Are Evolutionary Perspectives? 2016, 1-28. DOI: 10.1002/9781119125556.devpsy204.
- The International Deep Brain Stimulation Registry and Database for Gilles de la Tourette Syndrome: How Does It Work?Deeb W, Rossi PJ, Porta M, Visser-Vandewalle V, Servello D, Silburn P, Coyne T, Leckman JF, Foltynie T, Hariz M, Joyce EM, Zrinzo L, Kefalopoulou Z, Welter ML, Karachi C, Mallet L, Houeto JL, Shahed-Jimenez J, Meng FG, Klassen BT, Mogilner AY, Pourfar MH, Kuhn J, Ackermans L, Kaido T, Temel Y, Gross RE, Walker HC, Lozano AM, Khandhar SM, Walter BL, Walter E, Mari Z, Changizi BK, Moro E, Baldermann JC, Huys D, Zauber SE, Schrock LE, Zhang JG, Hu W, Foote KD, Rizer K, Mink JW, Woods DW, Gunduz A, Okun MS. The International Deep Brain Stimulation Registry and Database for Gilles de la Tourette Syndrome: How Does It Work? Frontiers In Neuroscience 2016, 10: 170. PMID: 27199634, PMCID: PMC4842757, DOI: 10.3389/fnins.2016.00170.
- On the Nature of Separation Challenges and Attachment Solutions in Severe, Refractory Gilles de la Tourette Syndrome (GTS): Deep Brain Stimulation (DBS) Has Been Helpful, But What About Rikki and Luci and Now Riley?Leckman J. On the Nature of Separation Challenges and Attachment Solutions in Severe, Refractory Gilles de la Tourette Syndrome (GTS): Deep Brain Stimulation (DBS) Has Been Helpful, But What About Rikki and Luci and Now Riley? 2016, 67-73. DOI: 10.1007/978-3-319-42190-2_12.
- Salivary oxytocin in clinically anxious youth: Associations with separation anxiety and family accommodationLebowitz ER, Leckman JF, Feldman R, Zagoory-Sharon O, McDonald N, Silverman WK. Salivary oxytocin in clinically anxious youth: Associations with separation anxiety and family accommodation Psychoneuroendocrinology 2015, 65: 35-43. PMID: 26716876, PMCID: PMC4895196, DOI: 10.1016/j.psyneuen.2015.12.007.
- A Prospective Longitudinal Study of Perceived Infant Outcomes at 18–24 Months: Neural and Psychological Correlates of Parental Thoughts and Actions Assessed during the First Month PostpartumKim P, Rigo P, Leckman JF, Mayes LC, Cole PM, Feldman R, Swain JE. A Prospective Longitudinal Study of Perceived Infant Outcomes at 18–24 Months: Neural and Psychological Correlates of Parental Thoughts and Actions Assessed during the First Month Postpartum Frontiers In Psychology 2015, 6: 1772. PMID: 26635679, PMCID: PMC4654106, DOI: 10.3389/fpsyg.2015.01772.
- Cognitive computer training in children with attention deficit hyperactivity disorder (ADHD) versus no intervention: study protocol for a randomized controlled trialBikic A, Leckman JF, Lindschou J, Christensen TØ, Dalsgaard S. Cognitive computer training in children with attention deficit hyperactivity disorder (ADHD) versus no intervention: study protocol for a randomized controlled trial Trials 2015, 16: 480. PMID: 26499057, PMCID: PMC4619562, DOI: 10.1186/s13063-015-0975-8.
- Violence, health, and South-North collaboration: Interdisciplinary research in light of the 2030 AgendaLee BX, Leckman JF, Khoshnood K. Violence, health, and South-North collaboration: Interdisciplinary research in light of the 2030 Agenda Social Science & Medicine 2015, 146: 236-242. PMID: 26516097, DOI: 10.1016/j.socscimed.2015.10.029.
- Intrapartum Oxytocin Use in Denmark and the Risk of Autism in Offspring.Dalsgaard S, Leckman J, Carter C, Harris J, Uldbjerg N, Henriksen T, Thygesen M, Mortensen P, Agerbo E. Intrapartum Oxytocin Use in Denmark and the Risk of Autism in Offspring. International Journal Of Epidemiology 2015, 44: i2-i2. DOI: 10.1093/ije/dyv097.004.
- Familial Risks of Tourette Syndrome and Chronic Tic Disorders: A Population-Based Cohort StudyMataix-Cols D, Isomura K, Pérez-Vigil A, Chang Z, Rück C, Larsson KJ, Leckman JF, Serlachius E, Larsson H, Lichtenstein P. Familial Risks of Tourette Syndrome and Chronic Tic Disorders: A Population-Based Cohort Study JAMA Psychiatry 2015, 72: 787-793. PMID: 26083307, DOI: 10.1001/jamapsychiatry.2015.0627.
- Effect of drugs on the risk of injuries in children with attention deficit hyperactivity disorder: a prospective cohort studyDalsgaard S, Leckman JF, Mortensen PB, Nielsen HS, Simonsen M. Effect of drugs on the risk of injuries in children with attention deficit hyperactivity disorder: a prospective cohort study The Lancet Psychiatry 2015, 2: 702-709. PMID: 26249301, DOI: 10.1016/s2215-0366(15)00271-0.
- Residential and foster careIJzendoorn M, Bakermans‐Kranenburg M, Scott S, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Residential and foster care 2015, 261-272. DOI: 10.1002/9781118381953.ch21.
- Physical examination and medical investigationTowbin K, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Physical examination and medical investigation 2015, 449-460. DOI: 10.1002/9781118381953.ch35.
- Systems neurosciencePine D, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Systems neuroscience 2015, 119-131. DOI: 10.1002/9781118381953.ch10.
- Gender dysphoria and paraphilic sexual disordersZucker K, Seto M, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Gender dysphoria and paraphilic sexual disorders 2015, 983-998. DOI: 10.1002/9781118381953.ch69.
- School‐based mental health interventionsMerry S, Moor S, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. School‐based mental health interventions 2015, 545-558. DOI: 10.1002/9781118381953.ch42.
- Neurobiological perspectives on developmental psychopathologyJohnson M, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Neurobiological perspectives on developmental psychopathology 2015, 105-118. DOI: 10.1002/9781118381953.ch9.
- Children with specific sensory impairmentsDale N, Edwards L, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Children with specific sensory impairments 2015, 612-622. DOI: 10.1002/9781118381953.ch47.
- Attachment: normal development, individual differences, and associations with experienceDozier M, Bernard K, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Attachment: normal development, individual differences, and associations with experience 2015, 65-78. DOI: 10.1002/9781118381953.ch6.
- Refugee, asylum‐seeking and internally displaced children and adolescentsFazel M, Reed R, Stein A, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Refugee, asylum‐seeking and internally displaced children and adolescents 2015, 573-585. DOI: 10.1002/9781118381953.ch44.
- Pharmacological, medically‐led and related treatmentsTaylor E, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Pharmacological, medically‐led and related treatments 2015, 559-572. DOI: 10.1002/9781118381953.ch43.
- Disorders of personalityHill J, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Disorders of personality 2015, 950-965. DOI: 10.1002/9781118381953.ch67.
- Conceptual issues and empirical challenges in the disruptive behavior disordersHill J, Maughan B, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Conceptual issues and empirical challenges in the disruptive behavior disorders 2015, 41-52. DOI: 10.1002/9781118381953.ch4.
- ADHD and hyperkinetic disorderSonuga‐Barke E, Taylor E, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. ADHD and hyperkinetic disorder 2015, 738-756. DOI: 10.1002/9781118381953.ch55.
- Psychological assessment in the clinical contextCharman T, Hood J, Howlin P, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Psychological assessment in the clinical context 2015, 436-448. DOI: 10.1002/9781118381953.ch34.
- Disorders of reading, mathematical and motor developmentSnowling M, Hulme C, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Disorders of reading, mathematical and motor development 2015, 702-718. DOI: 10.1002/9781118381953.ch53.
- Disorders of attachment and social engagement related to deprivationZeanah C, Smyke A, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Disorders of attachment and social engagement related to deprivation 2015, 793-805. DOI: 10.1002/9781118381953.ch58.
- Use of structured interviews, rating scales, and observational methods in clinical settingsFisher P, Chin E, Vidair H, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Use of structured interviews, rating scales, and observational methods in clinical settings 2015, 419-435. DOI: 10.1002/9781118381953.ch33.
- Anxiety disordersPine D, Klein R, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Anxiety disorders 2015, 822-840. DOI: 10.1002/9781118381953.ch60.
- Cognitive‐behavioral therapy, behavioral therapy, and related treatments in childrenKendall P, Peterman J, Cummings C, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Cognitive‐behavioral therapy, behavioral therapy, and related treatments in children 2015, 496-509. DOI: 10.1002/9781118381953.ch38.
- Educational interventions for children's learning difficultiesHulme C, Melby‐Lervåg M, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Educational interventions for children's learning difficulties 2015, 533-544. DOI: 10.1002/9781118381953.ch41.
- Forensic psychiatryYoung S, Church R, Thapar A, Pine D, Leckman J, Scott S, Snowling M, Taylor E. Forensic psychiatry 2015, 636-647. DOI: 10.1002/9781118381953.ch49.
- Meta-Analysis: Risk of Tics Associated With Psychostimulant Use in Randomized, Placebo-Controlled TrialsCohen SC, Mulqueen JM, Ferracioli-Oda E, Stuckelman ZD, Coughlin CG, Leckman JF, Bloch MH. Meta-Analysis: Risk of Tics Associated With Psychostimulant Use in Randomized, Placebo-Controlled Trials Journal Of The American Academy Of Child & Adolescent Psychiatry 2015, 54: 728-736. PMID: 26299294, DOI: 10.1016/j.jaac.2015.06.011.
- Obsessive–compulsive symptoms are associated with psychiatric comorbidities, behavioral and clinical problems: a population-based study of Brazilian school childrenAlvarenga PG, do Rosario MC, Cesar RC, Manfro GG, Moriyama TS, Bloch MH, Shavitt RG, Hoexter MQ, Coughlin CG, Leckman JF, Miguel EC. Obsessive–compulsive symptoms are associated with psychiatric comorbidities, behavioral and clinical problems: a population-based study of Brazilian school children European Child & Adolescent Psychiatry 2015, 25: 175-182. PMID: 26015374, DOI: 10.1007/s00787-015-0723-3.
- The association between 2D:4D ratio and cognitive empathy is contingent on a common polymorphism in the oxytocin receptor gene (OXTR rs53576)Weisman O, Pelphrey KA, Leckman JF, Feldman R, Lu Y, Chong A, Chen Y, Monakhov M, Chew SH, Ebstein RP. The association between 2D:4D ratio and cognitive empathy is contingent on a common polymorphism in the oxytocin receptor gene (OXTR rs53576) Psychoneuroendocrinology 2015, 58: 23-32. PMID: 25935637, DOI: 10.1016/j.psyneuen.2015.04.007.
- Maternal History of Autoimmune Disease and Later Development of Tourette Syndrome in OffspringDalsgaard S, Waltoft BL, Leckman JF, Mortensen PB. Maternal History of Autoimmune Disease and Later Development of Tourette Syndrome in Offspring Journal Of The American Academy Of Child & Adolescent Psychiatry 2015, 54: 495-501.e1. PMID: 26004665, DOI: 10.1016/j.jaac.2015.03.008.
- Mortality in children, adolescents, and adults with attention deficit hyperactivity disorder: a nationwide cohort studyDalsgaard S, Østergaard SD, Leckman JF, Mortensen PB, Pedersen MG. Mortality in children, adolescents, and adults with attention deficit hyperactivity disorder: a nationwide cohort study The Lancet 2015, 385: 2190-2196. PMID: 25726514, DOI: 10.1016/s0140-6736(14)61684-6.
- Oxytocin-augmented labor and risk for autism in malesWeisman O, Agerbo E, Carter CS, Harris JC, Uldbjerg N, Henriksen TB, Thygesen M, Mortensen PB, Leckman JF, Dalsgaard S. Oxytocin-augmented labor and risk for autism in males Behavioural Brain Research 2015, 284: 207-212. PMID: 25707712, DOI: 10.1016/j.bbr.2015.02.028.
- Obsessive-compulsive symptom dimensions in a population-based, cross-sectional sample of school-aged childrenAlvarenga PG, Cesar RC, Leckman JF, Moriyama TS, Torres AR, Bloch MH, Coughlin CG, Hoexter MQ, Manfro GG, Polanczyk GV, Miguel EC, do Rosario MC. Obsessive-compulsive symptom dimensions in a population-based, cross-sectional sample of school-aged children Journal Of Psychiatric Research 2015, 62: 108-114. PMID: 25702286, DOI: 10.1016/j.jpsychires.2015.01.018.
- Tourette syndrome deep brain stimulation: A review and updated recommendationsSchrock LE, Mink JW, Woods DW, Porta M, Servello D, Visser‐Vandewalle V, Silburn PA, Foltynie T, Walker HC, Shahed‐Jimenez J, Savica R, Klassen BT, Machado AG, Foote KD, Zhang J, Hu W, Ackermans L, Temel Y, Mari Z, Changizi BK, Lozano A, Auyeung M, Kaido T, Agid Y, Welter ML, Khandhar SM, Mogilner AY, Pourfar MH, Walter BL, Juncos JL, Gross RE, Kuhn J, Leckman JF, Neimat JA, Okun MS, Group T. Tourette syndrome deep brain stimulation: A review and updated recommendations Movement Disorders 2014, 30: 448-471. PMID: 25476818, DOI: 10.1002/mds.26094.
- Randomized Sham Controlled Double-blind Trial of Repetitive Transcranial Magnetic Stimulation for Adults With Severe Tourette SyndromeLanderos-Weisenberger A, Mantovani A, Motlagh MG, de Alvarenga PG, Katsovich L, Leckman JF, Lisanby SH. Randomized Sham Controlled Double-blind Trial of Repetitive Transcranial Magnetic Stimulation for Adults With Severe Tourette Syndrome Brain Stimulation 2014, 8: 574-581. PMID: 25912296, PMCID: PMC4454615, DOI: 10.1016/j.brs.2014.11.015.
- Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette’s Syndrome and OCDYu D, Mathews CA, Scharf JM, Neale BM, Davis LK, Gamazon ER, Derks EM, Evans P, Edlund CK, Crane J, Fagerness JA, Osiecki L, Gallagher P, Gerber G, Haddad S, Illmann C, McGrath LM, Mayerfeld C, Arepalli S, Barlassina C, Barr CL, Bellodi L, Benarroch F, Berrió GB, Bienvenu OJ, Black DW, Bloch MH, Brentani H, Bruun RD, Budman CL, Camarena B, Campbell DD, Cappi C, Silgado JC, Cavallini MC, Chavira DA, Chouinard S, Cook EH, Cookson MR, Coric V, Cullen B, Cusi D, Delorme R, Denys D, Dion Y, Eapen V, Egberts K, Falkai P, Fernandez T, Fournier E, Garrido H, Geller D, Gilbert DL, Girard SL, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Hardy J, Heiman GA, Hemmings SM, Herrera LD, Hezel DM, Hoekstra PJ, Jankovic J, Kennedy JL, King RA, Konkashbaev AI, Kremeyer B, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Liu C, Lochner C, Lowe TL, Lupoli S, Macciardi F, Maier W, Manunta P, Marconi M, McCracken JT, Mesa Restrepo SC, Moessner R, Moorjani P, Morgan J, Muller H, Murphy DL, Naarden AL, Nurmi E, Ochoa WC, Ophoff RA, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Rauch SL, Renner T, Reus VI, Richter MA, Riddle MA, Robertson MM, Romero R, Rosário MC, Rosenberg D, Ruhrmann S, Sabatti C, Salvi E, Sampaio AS, Samuels J, Sandor P, Service SK, Sheppard B, Singer HS, Smit JH, Stein DJ, Strengman E, Tischfield JA, Turiel M, Valencia Duarte AV, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Weale M, Weiss R, Wendland JR, Westenberg HG, Shugart YY, Hounie AG, Miguel EC, Nicolini H, Wagner M, Ruiz-Linares A, Cath DC, McMahon W, Posthuma D, Oostra BA, Nestadt G, Rouleau GA, Purcell S, Jenike MA, Heutink P, Hanna GL, Conti DV, Arnold PD, Freimer NB, Stewart SE, Knowles JA, Cox NJ, Pauls DL. Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette’s Syndrome and OCD American Journal Of Psychiatry 2014, 172: 82-93. PMID: 25158072, PMCID: PMC4282594, DOI: 10.1176/appi.ajp.2014.13101306.
- Disordered Eating and Food Restrictions in Children with PANDAS/PANSToufexis MD, Hommer R, Gerardi DM, Grant P, Rothschild L, D'Souza P, Williams K, Leckman J, Swedo SE, Murphy TK. Disordered Eating and Food Restrictions in Children with PANDAS/PANS Journal Of Child And Adolescent Psychopharmacology 2014, 25: 48-56. PMID: 25329522, PMCID: PMC4340640, DOI: 10.1089/cap.2014.0063.
- Editorial commentary: “What does immunology have to do with brain development and neuropsychiatric disorders?”Leckman JF, Vaccarino FM. Editorial commentary: “What does immunology have to do with brain development and neuropsychiatric disorders?” Brain Research 2014, 1617: 1-6. PMID: 25283746, DOI: 10.1016/j.brainres.2014.09.052.
- Successful Treatment of Tourette Syndrome With Electroconvulsive Therapy: A Case ReportGuo JN, Kothari JS, Leckman JF, Ostroff RB. Successful Treatment of Tourette Syndrome With Electroconvulsive Therapy: A Case Report Biological Psychiatry 2014, 79: e13-e14. PMID: 25481620, DOI: 10.1016/j.biopsych.2014.09.020.
- Pediatric Acute-Onset Neuropsychiatric SyndromeMurphy TK, Gerardi DM, Leckman JF. Pediatric Acute-Onset Neuropsychiatric Syndrome Psychiatric Clinics Of North America 2014, 37: 353-374. PMID: 25150567, DOI: 10.1016/j.psc.2014.06.001.
- Transcriptome Analysis of the Human Striatum in Tourette SyndromeLennington JB, Coppola G, Kataoka-Sasaki Y, Fernandez TV, Palejev D, Li Y, Huttner A, Pletikos M, Sestan N, Leckman JF, Vaccarino FM. Transcriptome Analysis of the Human Striatum in Tourette Syndrome Biological Psychiatry 2014, 79: 372-382. PMID: 25199956, PMCID: PMC4305353, DOI: 10.1016/j.biopsych.2014.07.018.
- Practitioner Review: Engaging fathers – recommendations for a game change in parenting interventions based on a systematic review of the global evidencePanter-Brick C, Burgess A, Eggerman M, McAllister F, Pruett K, Leckman JF. Practitioner Review: Engaging fathers – recommendations for a game change in parenting interventions based on a systematic review of the global evidence Journal Of Child Psychology And Psychiatry 2014, 55: 1187-1212. PMID: 24980187, PMCID: PMC4277854, DOI: 10.1111/jcpp.12280.
- Neural plasticity in fathers of human infantsKim P, Rigo P, Mayes LC, Feldman R, Leckman JF, Swain JE. Neural plasticity in fathers of human infants Social Neuroscience 2014, 9: 522-535. PMID: 24958358, PMCID: PMC4144350, DOI: 10.1080/17470919.2014.933713.
- Copy Number Variation in Obsessive-Compulsive Disorder and Tourette Syndrome: A Cross-Disorder StudyMcGrath LM, Yu D, Marshall C, Davis LK, Thiruvahindrapuram B, Li B, Cappi C, Gerber G, Wolf A, Schroeder FA, Osiecki L, O'Dushlaine C, Kirby A, Illmann C, Haddad S, Gallagher P, Fagerness JA, Barr CL, Bellodi L, Benarroch F, Bienvenu OJ, Black DW, Bloch MH, Bruun RD, Budman CL, Camarena B, Cath DC, Cavallini MC, Chouinard S, Coric V, Cullen B, Delorme R, Denys D, Derks EM, Dion Y, Rosário MC, Eapen V, Evans P, Falkai P, Fernandez TV, Garrido H, Geller D, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Heiman GA, Hemmings SM, Herrera LD, Hounie AG, Jankovic J, Kennedy JL, King RA, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Lochner C, Lowe TL, Lyon GJ, Macciardi F, Maier W, McCracken JT, McMahon W, Murphy DL, Naarden AL, Neale BM, Nurmi E, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Reus VI, Richter MA, Riddle M, Robertson MM, Rosenberg D, Rouleau GA, Ruhrmann S, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Tischfield JA, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Wendland JR, Shugart YY, Miguel EC, Nicolini H, Oostra BA, Moessner R, Wagner M, Ruiz-Linares A, Heutink P, Nestadt G, Freimer N, Petryshen T, Posthuma D, Jenike MA, Cox NJ, Hanna GL, Brentani H, Scherer SW, Arnold PD, Stewart SE, Mathews CA, Knowles JA, Cook EH, Pauls DL, Wang K, Scharf JM. Copy Number Variation in Obsessive-Compulsive Disorder and Tourette Syndrome: A Cross-Disorder Study Journal Of The American Academy Of Child & Adolescent Psychiatry 2014, 53: 910-919. PMID: 25062598, PMCID: PMC4218748, DOI: 10.1016/j.jaac.2014.04.022.
- Cardiovascular Safety of Stimulants in Children with Attention-Deficit/Hyperactivity Disorder: A Nationwide Prospective Cohort StudyDalsgaard S, Kvist AP, Leckman JF, Nielsen HS, Simonsen M. Cardiovascular Safety of Stimulants in Children with Attention-Deficit/Hyperactivity Disorder: A Nationwide Prospective Cohort Study Journal Of Child And Adolescent Psychopharmacology 2014, 24: 302-310. PMID: 24956171, PMCID: PMC4137345, DOI: 10.1089/cap.2014.0020.
- Meta-analysis: hoarding symptoms associated with poor treatment outcome in obsessive–compulsive disorderBloch MH, Bartley CA, Zipperer L, Jakubovski E, Landeros-Weisenberger A, Pittenger C, Leckman JF. Meta-analysis: hoarding symptoms associated with poor treatment outcome in obsessive–compulsive disorder Molecular Psychiatry 2014, 19: 1025-1030. PMID: 24912494, PMCID: PMC4169729, DOI: 10.1038/mp.2014.50.
- Commentary: What does immunology have to do with brain development and psychopathology? – a commentary on O'Connor et al. (2014)Leckman JF. Commentary: What does immunology have to do with brain development and psychopathology? – a commentary on O'Connor et al. (2014) Journal Of Child Psychology And Psychiatry 2014, 55: 632-634. PMID: 24840172, DOI: 10.1111/jcpp.12259.
- Gender and Injuries Predict Stimulant Medication UseDalsgaard S, Leckman JF, Nielsen HS, Simonsen M. Gender and Injuries Predict Stimulant Medication Use Journal Of Child And Adolescent Psychopharmacology 2014, 24: 253-259. PMID: 24813570, PMCID: PMC4064734, DOI: 10.1089/cap.2013.0101.
- Clinical features of Tourette syndrome and tic disordersLeckman JF, King RA, Bloch MH. Clinical features of Tourette syndrome and tic disorders Journal Of Obsessive-Compulsive And Related Disorders 2014, 3: 372-379. PMID: 30197854, PMCID: PMC6124690, DOI: 10.1016/j.jocrd.2014.03.004.
- The Modulating Role of Stress in the Onset and Course of Tourette’s SyndromeBuse J, Kirschbaum C, Leckman JF, Münchau A, Roessner V. The Modulating Role of Stress in the Onset and Course of Tourette’s Syndrome Behavior Modification 2014, 38: 184-216. PMID: 24516255, DOI: 10.1177/0145445514522056.
- From Attachment to Groups: Tapping Into the Neurobiology of Our InterconnectednessGordon I, Leckman JF, Berg DN. From Attachment to Groups: Tapping Into the Neurobiology of Our Interconnectedness Journal Of The American Academy Of Child & Adolescent Psychiatry 2014, 53: 130-132. PMID: 24472246, DOI: 10.1016/j.jaac.2013.10.012.
- Oxytocin enhances brain function in children with autismGordon I, Wyk B, Bennett RH, Cordeaux C, Lucas MV, Eilbott JA, Zagoory-Sharon O, Leckman JF, Feldman R, Pelphrey KA. Oxytocin enhances brain function in children with autism Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 20953-20958. PMID: 24297883, PMCID: PMC3876263, DOI: 10.1073/pnas.1312857110.
- Brain Human Monoclonal Autoantibody from Sydenham Chorea Targets Dopaminergic Neurons in Transgenic Mice and Signals Dopamine D2 Receptor: Implications in Human DiseaseCox CJ, Sharma M, Leckman JF, Zuccolo J, Zuccolo A, Kovoor A, Swedo SE, Cunningham MW. Brain Human Monoclonal Autoantibody from Sydenham Chorea Targets Dopaminergic Neurons in Transgenic Mice and Signals Dopamine D2 Receptor: Implications in Human Disease The Journal Of Immunology 2013, 191: 5524-5541. PMID: 24184556, PMCID: PMC3848617, DOI: 10.4049/jimmunol.1102592.
- Lessons Learned from Open-label Deep Brain Stimulation for Tourette Syndrome: Eight Cases over 7 YearsMotlagh MG, Smith ME, Landeros-Weisenberger A, Kobets AJ, King RA, Miravite J, de Lotbinière AC, Alterman RL, Mogilner AY, Pourfar MH, Okun MS, Leckman JF. Lessons Learned from Open-label Deep Brain Stimulation for Tourette Syndrome: Eight Cases over 7 Years Tremor And Other Hyperkinetic Movements 2013, 3: 03. PMID: 24255802, PMCID: PMC3822402, DOI: 10.5334/tohm.126.
- Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic ArchitectureDavis LK, Yu D, Keenan CL, Gamazon ER, Konkashbaev AI, Derks EM, Neale BM, Yang J, Lee SH, Evans P, Barr CL, Bellodi L, Benarroch F, Berrio GB, Bienvenu OJ, Bloch MH, Blom RM, Bruun RD, Budman CL, Camarena B, Campbell D, Cappi C, Silgado J, Cath DC, Cavallini MC, Chavira DA, Chouinard S, Conti DV, Cook EH, Coric V, Cullen BA, Deforce D, Delorme R, Dion Y, Edlund CK, Egberts K, Falkai P, Fernandez TV, Gallagher PJ, Garrido H, Geller D, Girard SL, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Haddad S, Heiman GA, Hemmings SM, Hounie AG, Illmann C, Jankovic J, Jenike MA, Kennedy JL, King RA, Kremeyer B, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Liu C, Lochner C, Lowe TL, Macciardi F, McCracken JT, McGrath LM, Restrepo S, Moessner R, Morgan J, Muller H, Murphy DL, Naarden AL, Ochoa WC, Ophoff RA, Osiecki L, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Rauch SL, Renner TJ, Reus VI, Richter MA, Riddle MA, Robertson MM, Romero R, Rosàrio MC, Rosenberg D, Rouleau GA, Ruhrmann S, Ruiz-Linares A, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Strengman E, Tischfield JA, Duarte A, Vallada H, Van Nieuwerburgh F, Veenstra-VanderWeele J, Walitza S, Wang Y, Wendland JR, Westenberg HG, Shugart YY, Miguel EC, McMahon W, Wagner M, Nicolini H, Posthuma D, Hanna GL, Heutink P, Denys D, Arnold PD, Oostra BA, Nestadt G, Freimer NB, Pauls DL, Wray NR, Stewart SE, Mathews CA, Knowles JA, Cox NJ, Scharf JM. Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture PLOS Genetics 2013, 9: e1003864. PMID: 24204291, PMCID: PMC3812053, DOI: 10.1371/journal.pgen.1003864.
- Does Early Mentorship in Child and Adolescent Psychiatry Make a Difference? The Klingenstein Third-Generation Foundation Medical Student Fellowship ProgramStein JA, Althoff R, Anders T, Davison Y, Edwards S, Frosch E, Horst R, Hudziak JJ, Hunt J, Joshi SV, Li Kitts R, Larson J, Leckman J, O’Brien J, Lowenhaupt E, Pruitt D, Malloy E, Martin A, Partner A, Sarles R, Sikich L, Wells L, Kolevzon A. Does Early Mentorship in Child and Adolescent Psychiatry Make a Difference? The Klingenstein Third-Generation Foundation Medical Student Fellowship Program Academic Psychiatry 2013, 37: 321-324. PMID: 24026370, DOI: 10.1176/appi.ap.12070136.
- Brain mechanisms for prepulse inhibition in adults with Tourette syndrome: Initial findingsZebardast N, Crowley MJ, Bloch MH, Mayes LC, Wyk BV, Leckman JF, Pelphrey KA, Swain JE. Brain mechanisms for prepulse inhibition in adults with Tourette syndrome: Initial findings Psychiatry Research 2013, 214: 33-41. PMID: 23916249, PMCID: PMC3932431, DOI: 10.1016/j.pscychresns.2013.05.009.
- Gene variants associated with antisocial behaviour: a latent variable approachBentley MJ, Lin H, Fernandez TV, Lee M, Yrigollen CM, Pakstis AJ, Katsovich L, Olds DL, Grigorenko EL, Leckman JF. Gene variants associated with antisocial behaviour: a latent variable approach Journal Of Child Psychology And Psychiatry 2013, 54: 1074-1085. PMID: 23822756, PMCID: PMC3766409, DOI: 10.1111/jcpp.12109.
- What's next for developmental psychiatry?Leckman JF. What's next for developmental psychiatry? World Psychiatry 2013, 12: 125-126. PMID: 23737415, PMCID: PMC3683258, DOI: 10.1002/wps.20029.
- LONG‐TERM OUTCOME IN ADULTS WITH OBSESSIVE‐COMPULSIVE DISORDERBloch MH, Green C, Kichuk SA, Dombrowski PA, Wasylink S, Billingslea E, Landeros‐Weisenberger A, Kelmendi B, Goodman WK, Leckman JF, Coric V, Pittenger C. LONG‐TERM OUTCOME IN ADULTS WITH OBSESSIVE‐COMPULSIVE DISORDER Depression And Anxiety 2013, 30: 716-722. PMID: 23532944, PMCID: PMC3932438, DOI: 10.1002/da.22103.
- The Risks and Benefits of Antidepressants to Treat Pediatric-Onset Depression and Anxiety Disorders: A Developmental PerspectiveLeckman JF. The Risks and Benefits of Antidepressants to Treat Pediatric-Onset Depression and Anxiety Disorders: A Developmental Perspective Psychotherapy And Psychosomatics 2013, 82: 129-131. PMID: 23548739, DOI: 10.1159/000345543.
- Editorial Commentary: Resilience in child development – interconnected pathways to wellbeingPanter‐Brick C, Leckman JF. Editorial Commentary: Resilience in child development – interconnected pathways to wellbeing Journal Of Child Psychology And Psychiatry 2013, 54: 333-336. PMID: 23517424, DOI: 10.1111/jcpp.12057.
- N-Acetylcysteine in the Treatment of Pediatric Trichotillomania: A Randomized, Double-Blind, Placebo-Controlled Add-On TrialBloch MH, Panza KE, Grant JE, Pittenger C, Leckman JF. N-Acetylcysteine in the Treatment of Pediatric Trichotillomania: A Randomized, Double-Blind, Placebo-Controlled Add-On Trial Journal Of The American Academy Of Child & Adolescent Psychiatry 2013, 52: 231-240. PMID: 23452680, PMCID: PMC3745012, DOI: 10.1016/j.jaac.2012.12.020.
- Developmental approaches to child psychopathology: longitudinal studies and implications for clinical practice.Séguin JR, Leckman JF. Developmental approaches to child psychopathology: longitudinal studies and implications for clinical practice. Journal Of The Canadian Academy Of Child And Adolescent Psychiatry = Journal De L'Academie Canadienne De Psychiatrie De L'enfant Et De L'adolescent 2013, 22: 3-5. PMID: 23390426, PMCID: PMC3565708.
- More than Two Dozen “Autisms”Mercadante MT, Leckman JF. More than Two Dozen “Autisms” Brazilian Journal Of Psychiatry 2013, 35: 3-4. PMID: 23567593, DOI: 10.1016/j.rbp.2013.01.003.
- Chapter Nine Neuroendocrine Aspects of Tourette SyndromeMartino D, Macerollo A, Leckman JF. Chapter Nine Neuroendocrine Aspects of Tourette Syndrome 2013, 112: 239-279. PMID: 24295624, DOI: 10.1016/b978-0-12-411546-0.00009-3.
- Clinical assessment of Tourette syndrome and tic disordersCohen SC, Leckman JF, Bloch MH. Clinical assessment of Tourette syndrome and tic disorders Neuroscience & Biobehavioral Reviews 2012, 37: 997-1007. PMID: 23206664, PMCID: PMC3674220, DOI: 10.1016/j.neubiorev.2012.11.013.
- Systematic review: Pharmacological treatment of tic disorders – Efficacy of antipsychotic and alpha-2 adrenergic agonist agentsWeisman H, Qureshi IA, Leckman JF, Scahill L, Bloch MH. Systematic review: Pharmacological treatment of tic disorders – Efficacy of antipsychotic and alpha-2 adrenergic agonist agents Neuroscience & Biobehavioral Reviews 2012, 37: 1162-1171. PMID: 23099282, PMCID: PMC3674207, DOI: 10.1016/j.neubiorev.2012.09.008.
- Early Postpartum Parental Preoccupation and Positive Parenting Thoughts: Relationship with Parent–Infant InteractionKim P, Mayes L, Feldman R, Leckman JF, Swain JE. Early Postpartum Parental Preoccupation and Positive Parenting Thoughts: Relationship with Parent–Infant Interaction Infant Mental Health Journal 2012, 34: 104-116. PMID: 26834300, PMCID: PMC4732877, DOI: 10.1002/imhj.21359.
- FAMILY ACCOMMODATION IN PEDIATRIC ANXIETY DISORDERSLebowitz ER, Woolston J, Bar‐Haim Y, Calvocoressi L, Dauser C, Warnick E, Scahill L, Chakir AR, Shechner T, Hermes H, Vitulano LA, King RA, Leckman JF. FAMILY ACCOMMODATION IN PEDIATRIC ANXIETY DISORDERS Depression And Anxiety 2012, 30: 47-54. PMID: 22965863, PMCID: PMC3932435, DOI: 10.1002/da.21998.
- Trajectory in obsessive-compulsive disorder comorbiditiesde Mathis MA, Diniz JB, Hounie AG, Shavitt RG, Fossaluza V, Ferrão Y, Leckman JF, de Bragança Pereira C, do Rosario MC, Miguel EC. Trajectory in obsessive-compulsive disorder comorbidities European Neuropsychopharmacology 2012, 23: 594-601. PMID: 22921470, DOI: 10.1016/j.euroneuro.2012.08.006.
- Genome-wide association study of Tourette's syndromeScharf JM, Yu D, Mathews CA, Neale BM, Stewart SE, Fagerness JA, Evans P, Gamazon E, Edlund CK, Service SK, Tikhomirov A, Osiecki L, Illmann C, Pluzhnikov A, Konkashbaev A, Davis LK, Han B, Crane J, Moorjani P, Crenshaw AT, Parkin MA, Reus VI, Lowe TL, Rangel-Lugo M, Chouinard S, Dion Y, Girard S, Cath DC, Smit JH, King RA, Fernandez TV, Leckman JF, Kidd KK, Kidd JR, Pakstis AJ, State MW, Herrera LD, Romero R, Fournier E, Sandor P, Barr CL, Phan N, Gross-Tsur V, Benarroch F, Pollak Y, Budman CL, Bruun RD, Erenberg G, Naarden AL, Lee PC, Weiss N, Kremeyer B, Berrío GB, Campbell DD, Cardona Silgado JC, Ochoa WC, Mesa Restrepo SC, Muller H, Valencia Duarte AV, Lyon GJ, Leppert M, Morgan J, Weiss R, Grados MA, Anderson K, Davarya S, Singer H, Walkup J, Jankovic J, Tischfield JA, Heiman GA, Gilbert DL, Hoekstra PJ, Robertson MM, Kurlan R, Liu C, Gibbs JR, Singleton A, Hardy J, Strengman E, Ophoff R, Wagner M, Moessner R, Mirel D, Posthuma D, Sabatti C, Eskin E, Conti D, Knowles J, Ruiz-Linares A, Rouleau G, Purcell S, Heutink P, Oostra B, McMahon W, Freimer N, Cox N, Pauls D. Genome-wide association study of Tourette's syndrome Molecular Psychiatry 2012, 18: 721-728. PMID: 22889924, PMCID: PMC3605224, DOI: 10.1038/mp.2012.69.
- Effects of Ketamine in Treatment-Refractory Obsessive-Compulsive DisorderBloch MH, Wasylink S, Landeros-Weisenberger A, Panza KE, Billingslea E, Leckman JF, Krystal JH, Bhagwagar Z, Sanacora G, Pittenger C. Effects of Ketamine in Treatment-Refractory Obsessive-Compulsive Disorder Biological Psychiatry 2012, 72: 964-970. PMID: 22784486, PMCID: PMC3667652, DOI: 10.1016/j.biopsych.2012.05.028.
- Meta-analysis of Long-Chain Polyunsaturated Fatty Acid Supplementation of Formula and Infant CognitionQawasmi A, Landeros-Weisenberger A, Leckman JF, Bloch MH. Meta-analysis of Long-Chain Polyunsaturated Fatty Acid Supplementation of Formula and Infant Cognition Pediatrics 2012, 129: 1141-1149. PMID: 22641753, PMCID: PMC3362904, DOI: 10.1542/peds.2011-2127.
- Editorial commentary: challenges and potential of DSM-5 and ICD-11 revisions.Leckman JF, Pine DS. Editorial commentary: challenges and potential of DSM-5 and ICD-11 revisions. Journal Of Child Psychology And Psychiatry, And Allied Disciplines 2012, 53: 449-53. PMID: 22486485, DOI: 10.1111/j.1469-7610.2012.02548.x.
- Tourette syndrome in youth with and without obsessive compulsive disorder and attention deficit hyperactivity disorderLebowitz ER, Motlagh MG, Katsovich L, King RA, Lombroso PJ, Grantz H, Lin H, Bentley MJ, Gilbert DL, Singer HS, Coffey BJ, the Tourette Syndrome Study Group, Kurlan RM, Leckman JF. Tourette syndrome in youth with and without obsessive compulsive disorder and attention deficit hyperactivity disorder European Child & Adolescent Psychiatry 2012, 21: 451-457. PMID: 22543961, PMCID: PMC3722559, DOI: 10.1007/s00787-012-0278-5.
- Behavioral, Pharmacological, and Immunological Abnormalities after Streptococcal Exposure: A Novel Rat Model of Sydenham Chorea and Related Neuropsychiatric DisordersBrimberg L, Benhar I, Mascaro-Blanco A, Alvarez K, Lotan D, Winter C, Klein J, Moses AE, Somnier FE, Leckman JF, Swedo SE, Cunningham MW, Joel D. Behavioral, Pharmacological, and Immunological Abnormalities after Streptococcal Exposure: A Novel Rat Model of Sydenham Chorea and Related Neuropsychiatric Disorders Neuropsychopharmacology 2012, 37: 2076-2087. PMID: 22534626, PMCID: PMC3398718, DOI: 10.1038/npp.2012.56.
- Oxytocin during the initial stages of romantic attachment: Relations to couples’ interactive reciprocitySchneiderman I, Zagoory-Sharon O, Leckman JF, Feldman R. Oxytocin during the initial stages of romantic attachment: Relations to couples’ interactive reciprocity Psychoneuroendocrinology 2012, 37: 1277-1285. PMID: 22281209, PMCID: PMC3936960, DOI: 10.1016/j.psyneuen.2011.12.021.
- Tic disorders.Leckman JF. Tic disorders. BMJ (Clinical Research Ed.) 2012, 344: d7659. PMID: 22223834, DOI: 10.1136/bmj.d7659.
- Rare Copy Number Variants in Tourette Syndrome Disrupt Genes in Histaminergic Pathways and Overlap with AutismFernandez TV, Sanders SJ, Yurkiewicz IR, Ercan-Sencicek AG, Kim YS, Fishman DO, Raubeson MJ, Song Y, Yasuno K, Ho WS, Bilguvar K, Glessner J, Chu SH, Leckman JF, King RA, Gilbert DL, Heiman GA, Tischfield JA, Hoekstra PJ, Devlin B, Hakonarson H, Mane SM, Günel M, State MW. Rare Copy Number Variants in Tourette Syndrome Disrupt Genes in Histaminergic Pathways and Overlap with Autism Biological Psychiatry 2011, 71: 392-402. PMID: 22169095, PMCID: PMC3282144, DOI: 10.1016/j.biopsych.2011.09.034.
- Involvement of immunologic and biochemical mechanisms in the pathogenesis of Tourette’s syndromeLandau YE, Steinberg T, Richmand B, Leckman JF, Apter A. Involvement of immunologic and biochemical mechanisms in the pathogenesis of Tourette’s syndrome Journal Of Neural Transmission 2011, 119: 621-626. PMID: 22139323, PMCID: PMC3936959, DOI: 10.1007/s00702-011-0739-x.
- Love Alters Autonomic Reactivity to EmotionsSchneiderman I, Zilberstein-Kra Y, Leckman JF, Feldman R. Love Alters Autonomic Reactivity to Emotions Emotion 2011, 11: 1314-1321. PMID: 22142209, DOI: 10.1037/a0024090.
- Variations in Maternal Behavior—Oxytocin and Reward Pathways—Peripheral Measures Matter?!Leckman JF. Variations in Maternal Behavior—Oxytocin and Reward Pathways—Peripheral Measures Matter?! Neuropsychopharmacology 2011, 36: 2587-2588. PMID: 22071897, PMCID: PMC3230502, DOI: 10.1038/npp.2011.201.
- Risperidone-Related Improvement of Irritability in Children with Autism Is not Associated with Changes in Serum of Epidermal Growth Factor and Interleukin-13Tobiasova Z, van der Lingen KH, Scahill L, Leckman JF, Zhang Y, Chae W, McCracken JT, McDougle CJ, Vitiello B, Tierney E, Aman MG, Arnold LE, Katsovich L, Hoekstra PJ, Volkmar F, Bothwell AL, Kawikova I. Risperidone-Related Improvement of Irritability in Children with Autism Is not Associated with Changes in Serum of Epidermal Growth Factor and Interleukin-13 Journal Of Child And Adolescent Psychopharmacology 2011, 21: 555-564. PMID: 22070180, PMCID: PMC3279715, DOI: 10.1089/cap.2010.0134.
- Editorial Perspective: When OCD takes over…the family! Coercive and disruptive behaviours in paediatric obsessive compulsive disorderLebowitz ER, Vitulano LA, Mataix‐Cols D, Leckman JF. Editorial Perspective: When OCD takes over…the family! Coercive and disruptive behaviours in paediatric obsessive compulsive disorder Journal Of Child Psychology And Psychiatry 2011, 52: 1249-1250. PMID: 22022883, DOI: 10.1111/j.1469-7610.2011.02480.x.
- Oxytocin and social motivationGordon I, Martin C, Feldman R, Leckman JF. Oxytocin and social motivation Developmental Cognitive Neuroscience 2011, 1: 471-493. PMID: 21984889, PMCID: PMC3185363, DOI: 10.1016/j.dcn.2011.07.007.
- Early interventions to prevent mental disorders - learning lessons from the field of psychosisMoriyama TS, Miguel EC, Leckman J. Early interventions to prevent mental disorders - learning lessons from the field of psychosis Brazilian Journal Of Psychiatry 2011, 33: s125-s128. PMID: 22286563, DOI: 10.1590/s1516-44462011000600001.
- Thank Goodness for Uncle Sam and the National Institute of Mental Health Intramural ProgramLeckman JF. Thank Goodness for Uncle Sam and the National Institute of Mental Health Intramural Program Journal Of The American Academy Of Child & Adolescent Psychiatry 2011, 50: 851-853. PMID: 21871365, DOI: 10.1016/j.jaac.2010.04.012.
- Coercive and disruptive behaviors in pediatric obsessive–compulsive disorderLebowitz ER, Omer H, Leckman JF. Coercive and disruptive behaviors in pediatric obsessive–compulsive disorder Depression And Anxiety 2011, 28: 899-905. PMID: 21769998, PMCID: PMC4006629, DOI: 10.1002/da.20858.
- The familial association of tourette's disorder and ADHD: The impact of OCD symptomsO'Rourke JA, Scharf JM, Platko J, Stewart SE, Illmann C, Geller DA, King RA, Leckman JF, Pauls DL. The familial association of tourette's disorder and ADHD: The impact of OCD symptoms American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2011, 156: 553-560. PMID: 21557467, PMCID: PMC3292860, DOI: 10.1002/ajmg.b.31195.
- Breastfeeding, brain activation to own infant cry, and maternal sensitivityKim P, Feldman R, Mayes LC, Eicher V, Thompson N, Leckman JF, Swain JE. Breastfeeding, brain activation to own infant cry, and maternal sensitivity Journal Of Child Psychology And Psychiatry 2011, 52: 907-915. PMID: 21501165, PMCID: PMC3134570, DOI: 10.1111/j.1469-7610.2011.02406.x.
- Editorial: Developmental neuroscience comes of age.Leckman JF, March JS. Editorial: Developmental neuroscience comes of age. Journal Of Child Psychology And Psychiatry, And Allied Disciplines 2011, 52: 333-8. PMID: 21410471, DOI: 10.1111/j.1469-7610.2011.02378.x.
- Poor fine‐motor and visuospatial skills predict persistence of pediatric‐onset obsessive‐compulsive disorder into adulthoodBloch MH, Sukhodolsky DG, Dombrowski PA, Panza KE, Craiglow BG, Landeros‐Weisenberger A, Leckman JF, Peterson BS, Schultz RT. Poor fine‐motor and visuospatial skills predict persistence of pediatric‐onset obsessive‐compulsive disorder into adulthood Journal Of Child Psychology And Psychiatry 2011, 52: 974-983. PMID: 21244423, PMCID: PMC3625937, DOI: 10.1111/j.1469-7610.2010.02366.x.
- Biofeedback of Real-Time Functional Magnetic Resonance Imaging Data from the Supplementary Motor Area Reduces Functional Connectivity to Subcortical RegionsHampson M, Scheinost D, Qiu M, Bhawnani J, Lacadie CM, Leckman JF, Constable RT, Papademetris X. Biofeedback of Real-Time Functional Magnetic Resonance Imaging Data from the Supplementary Motor Area Reduces Functional Connectivity to Subcortical Regions Brain Connectivity 2011, 1: 91-98. PMID: 22432958, PMCID: PMC3621512, DOI: 10.1089/brain.2011.0002.
- Streptococcal Upper Respiratory Tract Infections and Exacerbations of Tic and Obsessive-Compulsive Symptoms: A Prospective Longitudinal StudyLeckman JF, King RA, Gilbert DL, Coffey BJ, Singer HS, Dure LS, Grantz H, Katsovich L, Lin H, Lombroso PJ, Kawikova I, Johnson DR, Kurlan RM, Kaplan EL. Streptococcal Upper Respiratory Tract Infections and Exacerbations of Tic and Obsessive-Compulsive Symptoms: A Prospective Longitudinal Study Journal Of The American Academy Of Child & Adolescent Psychiatry 2010, 50: 108-118.e3. PMID: 21241948, PMCID: PMC3024577, DOI: 10.1016/j.jaac.2010.10.011.
- Altered immunoglobulin profiles in children with Tourette syndromeBos-Veneman NG, Olieman R, Tobiasova Z, Hoekstra PJ, Katsovich L, Bothwell AL, Leckman JF, Kawikova I. Altered immunoglobulin profiles in children with Tourette syndrome Brain Behavior And Immunity 2010, 25: 532-538. PMID: 21156204, PMCID: PMC3056238, DOI: 10.1016/j.bbi.2010.12.003.
- Neuropsychological Functioning in Children With Tourette Syndrome With and Without Attention-Deficit/Hyperactivity DisorderSukhodolsky DG, Landeros-Weisenberger A, Scahill L, Leckman JF, Schultz RT. Neuropsychological Functioning in Children With Tourette Syndrome With and Without Attention-Deficit/Hyperactivity Disorder Journal Of The American Academy Of Child & Adolescent Psychiatry 2010, 49: 1155-1164.e1. PMID: 20970703, PMCID: PMC2965169, DOI: 10.1016/j.jaac.2010.08.008.
- The Plasticity of Human Maternal Brain: Longitudinal Changes in Brain Anatomy During the Early Postpartum PeriodKim P, Leckman JF, Mayes LC, Feldman R, Wang X, Swain JE. The Plasticity of Human Maternal Brain: Longitudinal Changes in Brain Anatomy During the Early Postpartum Period Behavioral Neuroscience 2010, 124: 695-700. PMID: 20939669, PMCID: PMC4318549, DOI: 10.1037/a0020884.
- Tourette Syndrome in Children: An Updated ReviewDu JC, Chiu TF, Lee KM, Wu HL, Yang YC, Hsu SY, Sun CS, Hwang B, Leckman JF. Tourette Syndrome in Children: An Updated Review Pediatrics & Neonatology 2010, 51: 255-264. PMID: 20951354, DOI: 10.1016/s1875-9572(10)60050-2.
- Oxytocin, cortisol, and triadic family interactionsGordon I, Zagoory-Sharon O, Leckman JF, Feldman R. Oxytocin, cortisol, and triadic family interactions Physiology & Behavior 2010, 101: 679-684. PMID: 20723553, DOI: 10.1016/j.physbeh.2010.08.008.
- Pathological laughter in Gilles de la Tourette syndrome: An unusual phonic ticCavanna AE, Ali F, Leckman JF, Robertson MM. Pathological laughter in Gilles de la Tourette syndrome: An unusual phonic tic Movement Disorders 2010, 25: 2233-2239. PMID: 20683924, DOI: 10.1002/mds.23216.
- Neurobiological Substrates of Tourette's DisorderLeckman JF, Bloch MH, Smith ME, Larabi D, Hampson M. Neurobiological Substrates of Tourette's Disorder Journal Of Child And Adolescent Psychopharmacology 2010, 20: 237-247. PMID: 20807062, PMCID: PMC2958453, DOI: 10.1089/cap.2009.0118.
- The Immunobiology of Tourette's Disorder, Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus, and Related Disorders: A Way ForwardMurphy TK, Kurlan R, Leckman J. The Immunobiology of Tourette's Disorder, Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus, and Related Disorders: A Way Forward Journal Of Child And Adolescent Psychopharmacology 2010, 20: 317-331. PMID: 20807070, PMCID: PMC4003464, DOI: 10.1089/cap.2010.0043.
- Adverse Effects of Heavy Prenatal Maternal Smoking on Attentional Control in Children With ADHDMotlagh MG, Sukhodolsky DG, Landeros-Weisenberger A, Katsovich L, Thompson N, Scahill L, King RA, Peterson BS, Schultz RT, Leckman JF. Adverse Effects of Heavy Prenatal Maternal Smoking on Attentional Control in Children With ADHD Journal Of Attention Disorders 2010, 15: 593-603. PMID: 20616372, PMCID: PMC3974616, DOI: 10.1177/1087054710374576.
- Psychosocial outcome and psychiatric comorbidity in older adolescents with Tourette syndrome: controlled studyGorman DA, Thompson N, Plessen KJ, Robertson MM, Leckman JF, Peterson BS. Psychosocial outcome and psychiatric comorbidity in older adolescents with Tourette syndrome: controlled study The British Journal Of Psychiatry 2010, 197: 36-44. PMID: 20592431, PMCID: PMC2894981, DOI: 10.1192/bjp.bp.109.071050.
- Severe psychosocial stress and heavy cigarette smoking during pregnancy: an examination of the pre- and perinatal risk factors associated with ADHD and Tourette syndromeMotlagh MG, Katsovich L, Thompson N, Lin H, Kim YS, Scahill L, Lombroso PJ, King RA, Peterson BS, Leckman JF. Severe psychosocial stress and heavy cigarette smoking during pregnancy: an examination of the pre- and perinatal risk factors associated with ADHD and Tourette syndrome European Child & Adolescent Psychiatry 2010, 19: 755-764. PMID: 20532931, PMCID: PMC3932440, DOI: 10.1007/s00787-010-0115-7.
- Should OCD be classified as an anxiety disorder in DSM‐V?Stein DJ, Fineberg NA, Bienvenu OJ, Denys D, Lochner C, Nestadt G, Leckman JF, Rauch SL, Phillips KA. Should OCD be classified as an anxiety disorder in DSM‐V? Depression And Anxiety 2010, 27: 495-506. PMID: 20533366, DOI: 10.1002/da.20699.
- Should an obsessive–compulsive spectrum grouping of disorders be included in DSM‐V?Phillips KA, Stein DJ, Rauch SL, Hollander E, Fallon BA, Barsky A, Fineberg N, Mataix‐Cols D, Ferrão YA, Saxena S, Wilhelm S, Kelly MM, Clark LA, Pinto A, Bienvenu OJ, Farrow J, Leckman J. Should an obsessive–compulsive spectrum grouping of disorders be included in DSM‐V? Depression And Anxiety 2010, 27: 528-555. PMID: 20533367, PMCID: PMC3985410, DOI: 10.1002/da.20705.
- Tic disorders: some key issues for DSM‐VWalkup JT, Ferrão Y, Leckman JF, Stein DJ, Singer H. Tic disorders: some key issues for DSM‐V Depression And Anxiety 2010, 27: 600-610. PMID: 20533370, DOI: 10.1002/da.20711.
- Prolactin, Oxytocin, and the development of paternal behavior across the first six months of fatherhoodGordon I, Zagoory-Sharon O, Leckman JF, Feldman R. Prolactin, Oxytocin, and the development of paternal behavior across the first six months of fatherhood Hormones And Behavior 2010, 58: 513-518. PMID: 20399783, PMCID: PMC3247300, DOI: 10.1016/j.yhbeh.2010.04.007.
- Oxytocin and the Development of Parenting in HumansGordon I, Zagoory-Sharon O, Leckman JF, Feldman R. Oxytocin and the Development of Parenting in Humans Biological Psychiatry 2010, 68: 377-382. PMID: 20359699, PMCID: PMC3943240, DOI: 10.1016/j.biopsych.2010.02.005.
- Hoarding disorder: a new diagnosis for DSM‐V?Mataix‐Cols D, Frost RO, Pertusa A, Clark LA, Saxena S, Leckman JF, Stein DJ, Matsunaga H, Wilhelm S. Hoarding disorder: a new diagnosis for DSM‐V? Depression And Anxiety 2010, 27: 556-572. PMID: 20336805, DOI: 10.1002/da.20693.
- Obsessive–compulsive disorder: a review of the diagnostic criteria and possible subtypes and dimensional specifiers for DSM‐VLeckman JF, Denys D, Simpson HB, Mataix‐Cols D, Hollander E, Saxena S, Miguel EC, Rauch SL, Goodman WK, Phillips KA, Stein DJ. Obsessive–compulsive disorder: a review of the diagnostic criteria and possible subtypes and dimensional specifiers for DSM‐V Depression And Anxiety 2010, 27: 507-527. PMID: 20217853, PMCID: PMC3974619, DOI: 10.1002/da.20669.
- Elevated expression of MCP-1, IL-2 and PTPR-N in basal ganglia of Tourette syndrome casesMorer A, Chae W, Henegariu O, Bothwell AL, Leckman JF, Kawikova I. Elevated expression of MCP-1, IL-2 and PTPR-N in basal ganglia of Tourette syndrome cases Brain Behavior And Immunity 2010, 24: 1069-1073. PMID: 20193755, DOI: 10.1016/j.bbi.2010.02.007.
- Predictors of early adulthood quality of life in children with obsessive–compulsive disorderPalermo SD, Bloch MH, Craiglow B, Landeros-Weisenberger A, Dombrowski PA, Panza K, Smith ME, Peterson BS, Leckman JF. Predictors of early adulthood quality of life in children with obsessive–compulsive disorder Social Psychiatry And Psychiatric Epidemiology 2010, 46: 291-297. PMID: 20191262, PMCID: PMC3645906, DOI: 10.1007/s00127-010-0194-2.
- Editorial: Developmental transitions to psychopathology: from genomics and epigenomics to social policyLeckman JF, Yazgan MY. Editorial: Developmental transitions to psychopathology: from genomics and epigenomics to social policy Journal Of Child Psychology And Psychiatry 2010, 51: 333-340. PMID: 20180880, DOI: 10.1111/j.1469-7610.2010.02226.x.
- The Human Immune Response to Streptococcal Extracellular Antigens: Clinical, Diagnostic, and Potential Pathogenetic ImplicationsJohnson DR, Kurlan R, Leckman J, Kaplan EL. The Human Immune Response to Streptococcal Extracellular Antigens: Clinical, Diagnostic, and Potential Pathogenetic Implications Clinical Infectious Diseases 2010, 50: 481-490. PMID: 20067422, DOI: 10.1086/650167.
- Refining the diagnostic boundaries of compulsive hoarding: A critical reviewPertusa A, Frost RO, Fullana MA, Samuels J, Steketee G, Tolin D, Saxena S, Leckman JF, Mataix-Cols D. Refining the diagnostic boundaries of compulsive hoarding: A critical review Clinical Psychology Review 2010, 30: 371-386. PMID: 20189280, DOI: 10.1016/j.cpr.2010.01.007.
- Autism spectrum and obsessive–compulsive disorders: OC behaviors, phenotypes and geneticsJacob S, Landeros‐Weisenberger A, Leckman JF. Autism spectrum and obsessive–compulsive disorders: OC behaviors, phenotypes and genetics Autism Research 2009, 2: 293-311. PMID: 20029829, PMCID: PMC3974607, DOI: 10.1002/aur.108.
- Children with Tourette's Syndrome May Suffer Immunoglobulin A Dysgammaglobulinemia: Preliminary ReportKawikova I, Grady BP, Tobiasova Z, Zhang Y, Vojdani A, Katsovich L, Richmand BJ, Park TW, Bothwell AL, Leckman JF. Children with Tourette's Syndrome May Suffer Immunoglobulin A Dysgammaglobulinemia: Preliminary Report Biological Psychiatry 2009, 67: 679-683. PMID: 20006327, PMCID: PMC3974615, DOI: 10.1016/j.biopsych.2009.09.034.
- Clinical course of Tourette syndromeBloch MH, Leckman JF. Clinical course of Tourette syndrome Journal Of Psychosomatic Research 2009, 67: 497-501. PMID: 19913654, PMCID: PMC3974606, DOI: 10.1016/j.jpsychores.2009.09.002.
- Streptococcal Upper Respiratory Tract Infections and Psychosocial Stress Predict Future Tic and Obsessive-Compulsive Symptom Severity in Children and Adolescents with Tourette Syndrome and Obsessive-Compulsive DisorderLin H, Williams KA, Katsovich L, Findley DB, Grantz H, Lombroso PJ, King RA, Bessen DE, Johnson D, Kaplan EL, Landeros-Weisenberger A, Zhang H, Leckman JF. Streptococcal Upper Respiratory Tract Infections and Psychosocial Stress Predict Future Tic and Obsessive-Compulsive Symptom Severity in Children and Adolescents with Tourette Syndrome and Obsessive-Compulsive Disorder Biological Psychiatry 2009, 67: 684-691. PMID: 19833320, PMCID: PMC2843763, DOI: 10.1016/j.biopsych.2009.08.020.
- Predictors of Early Adult Outcomes in Pediatric-Onset Obsessive-Compulsive DisorderBloch MH, Craiglow BG, Landeros-Weisenberger A, Dombrowski PA, Panza KE, Peterson BS, Leckman JF. Predictors of Early Adult Outcomes in Pediatric-Onset Obsessive-Compulsive Disorder Pediatrics 2009, 124: 1085-1093. PMID: 19786445, PMCID: PMC3974608, DOI: 10.1542/peds.2009-0015.
- Perceived quality of maternal care in childhood and structure and function of mothers' brainKim P, Leckman JF, Mayes LC, Newman M, Feldman R, Swain JE. Perceived quality of maternal care in childhood and structure and function of mothers' brain Developmental Science 2009, 13: 662-673. PMID: 20590729, PMCID: PMC3974609, DOI: 10.1111/j.1467-7687.2009.00923.x.
- Decreased number of parvalbumin and cholinergic interneurons in the striatum of individuals with Tourette syndromeKataoka Y, Kalanithi PS, Grantz H, Schwartz ML, Saper C, Leckman JF, Vaccarino FM. Decreased number of parvalbumin and cholinergic interneurons in the striatum of individuals with Tourette syndrome The Journal Of Comparative Neurology 2009, 518: 277-291. PMID: 19941350, PMCID: PMC2846837, DOI: 10.1002/cne.22206.
- Meta-Analysis: Treatment of Attention-Deficit/Hyperactivity Disorder in Children With Comorbid Tic DisordersBloch MH, Panza KE, Landeros-Weisenberger A, Leckman JF. Meta-Analysis: Treatment of Attention-Deficit/Hyperactivity Disorder in Children With Comorbid Tic Disorders Journal Of The American Academy Of Child & Adolescent Psychiatry 2009, 48: 884-893. PMID: 19625978, PMCID: PMC3943246, DOI: 10.1097/chi.0b013e3181b26e9f.
- Obsessive–compulsive Disorder: Diagnostic and Treatment IssuesStein DJ, Denys D, Gloster AT, Hollander E, Leckman JF, Rauch SL, Phillips KA. Obsessive–compulsive Disorder: Diagnostic and Treatment Issues Psychiatric Clinics Of North America 2009, 32: 665-685. PMID: 19716996, DOI: 10.1016/j.psc.2009.05.007.
- Dimensional predictors of response to SRI pharmacotherapy in obsessive–compulsive disorderLanderos-Weisenberger A, Bloch MH, Kelmendi B, Wegner R, Nudel J, Dombrowski P, Pittenger C, Krystal JH, Goodman WK, Leckman JF, Coric V. Dimensional predictors of response to SRI pharmacotherapy in obsessive–compulsive disorder Journal Of Affective Disorders 2009, 121: 175-179. PMID: 19577308, PMCID: PMC3974618, DOI: 10.1016/j.jad.2009.06.010.
- Validation of the University of São Paulo Sensory Phenomena Scale:Initial Psychometric PropertiesRosario MC, Prado HS, Borcato S, Diniz JB, Shavitt RG, Hounie AG, Mathis ME, Mastrorosa RS, Velloso P, Perin EA, Fossaluza V, Pereira CA, Geller D, Leckman J, Miguel E. Validation of the University of São Paulo Sensory Phenomena Scale:Initial Psychometric Properties CNS Spectrums 2009, 14: 315-323. PMID: 19668122, DOI: 10.1017/s1092852900020319.
- Meta-analysis of the dose-response relationship of SSRI in obsessive-compulsive disorderBloch MH, McGuire J, Landeros-Weisenberger A, Leckman JF, Pittenger C. Meta-analysis of the dose-response relationship of SSRI in obsessive-compulsive disorder Molecular Psychiatry 2009, 15: 850-855. PMID: 19468281, PMCID: PMC2888928, DOI: 10.1038/mp.2009.50.
- Immunopathogenic mechanisms in tourette syndrome: A critical reviewMartino D, Dale RC, Gilbert DL, Giovannoni G, Leckman JF. Immunopathogenic mechanisms in tourette syndrome: A critical review Movement Disorders 2009, 24: 1267-1279. PMID: 19353683, PMCID: PMC3972005, DOI: 10.1002/mds.22504.
- Randomized Trial of Anger Control Training for Adolescents With Tourette's Syndrome and Disruptive BehaviorSukhodolsky DG, Vitulano LA, Carroll DH, McGuire J, Leckman JF, Scahill L. Randomized Trial of Anger Control Training for Adolescents With Tourette's Syndrome and Disruptive Behavior Journal Of The American Academy Of Child & Adolescent Psychiatry 2009, 48: 413-421. PMID: 19242384, DOI: 10.1097/chi.0b013e3181985050.
- Symptom dimensions and subtypes of obsessive-compulsive disorder: a developmental perspectiveLeckman JF, Bloch MH, King RA. Symptom dimensions and subtypes of obsessive-compulsive disorder: a developmental perspective Dialogues In Clinical Neuroscience 2009, 11: 21-33. PMID: 19432385, PMCID: PMC3181902, DOI: 10.31887/dcns.2009.11.1/jfleckman.
- Risk and Resilience: Early Manipulation of Macaque Social Experience and Persistent Behavioral and Neurophysiological OutcomesStevens HE, Leckman JF, Coplan JD, Suomi SJ. Risk and Resilience: Early Manipulation of Macaque Social Experience and Persistent Behavioral and Neurophysiological Outcomes Journal Of The American Academy Of Child & Adolescent Psychiatry 2009, 48: 114-127. PMID: 19127170, DOI: 10.1097/chi.0b013e318193064c.
- Editorial: Envisioning the Future after 50 Years of Science and DiscoveryCharman T, Leckman J, Verhulst F. Editorial: Envisioning the Future after 50 Years of Science and Discovery Journal Of Child Psychology And Psychiatry 2009, 50: 1-1. PMID: 19220585, DOI: 10.1111/j.1469-7610.2008.02063.x.
- Perfectionism and sensory phenomena: phenotypic components of obsessive-compulsive disorderLee JC, Prado HS, Diniz JB, Borcato S, da Silva CB, Hounie AG, Miguel EC, Leckman JF, do Rosário MC. Perfectionism and sensory phenomena: phenotypic components of obsessive-compulsive disorder Comprehensive Psychiatry 2009, 50: 431-436. PMID: 19683613, DOI: 10.1016/j.comppsych.2008.11.007.
- Brain Areas Coactivating with Motor Cortex During Chronic Motor Tics and Intentional MovementsHampson M, Tokoglu F, King RA, Constable RT, Leckman JF. Brain Areas Coactivating with Motor Cortex During Chronic Motor Tics and Intentional Movements Biological Psychiatry 2008, 65: 594-599. PMID: 19111281, PMCID: PMC2679868, DOI: 10.1016/j.biopsych.2008.11.012.
- Meta-Analysis of the Symptom Structure of Obsessive-Compulsive DisorderBloch MH, Landeros-Weisenberger A, Rosario MC, Pittenger C, Leckman JF. Meta-Analysis of the Symptom Structure of Obsessive-Compulsive Disorder American Journal Of Psychiatry 2008, 165: 1532-1542. PMID: 18923068, PMCID: PMC3972003, DOI: 10.1176/appi.ajp.2008.08020320.
- Romantic attraction and conflict negotiation among late adolescent and early adult romantic couplesShulman S, Mayes LC, Cohen TH, Swain JE, Leckman JF. Romantic attraction and conflict negotiation among late adolescent and early adult romantic couples Journal Of Adolescence 2008, 31: 729-745. PMID: 18835494, PMCID: PMC3247301, DOI: 10.1016/j.adolescence.2008.02.002.
- A Developmental and Evolutionary Perspective on Obsessive-Compulsive Disorder: Whence and Whither Compulsive Hoarding?Leckman JF, Bloch MH. A Developmental and Evolutionary Perspective on Obsessive-Compulsive Disorder: Whence and Whither Compulsive Hoarding? American Journal Of Psychiatry 2008, 165: 1229-1233. PMID: 18829875, DOI: 10.1176/appi.ajp.2008.08060891.
- Neuropsychiatric Disorders Associated With Streptococcal InfectionLESLIE DL, KOZMA L, MARTIN A, LANDEROS A, KATSOVICH L, KING RA, LECKMAN JF. Neuropsychiatric Disorders Associated With Streptococcal Infection Journal Of The American Academy Of Child & Adolescent Psychiatry 2008, 47: 1166-1172. PMID: 18724258, PMCID: PMC2783578, DOI: 10.1097/chi.0b013e3181825a3d.
- Consanguineous Iranian kindreds with severe Tourette syndromeMotlagh MG, Seddigh A, Dashti B, Leckman JF, Alaghband‐Rad J. Consanguineous Iranian kindreds with severe Tourette syndrome Movement Disorders 2008, 23: 2079-2083. PMID: 18785237, PMCID: PMC3972002, DOI: 10.1002/mds.22261.
- Maternal brain response to own baby‐cry is affected by cesarean section deliverySwain JE, Tasgin E, Mayes LC, Feldman R, Constable RT, Leckman JF. Maternal brain response to own baby‐cry is affected by cesarean section delivery Journal Of Child Psychology And Psychiatry 2008, 49: 1042-1052. PMID: 18771508, PMCID: PMC3246837, DOI: 10.1111/j.1469-7610.2008.01963.x.
- Model Curriculum for Academic Child and Adolescent Psychiatry TrainingStubbe D, Martin A, Bloch M, Belitsky R, Carter D, Ebert M, Friedman A, Giese A, Kirwin P, Ross RG, Leckman JF. Model Curriculum for Academic Child and Adolescent Psychiatry Training Academic Psychiatry 2008, 32: 366-376. PMID: 18945975, DOI: 10.1176/appi.ap.32.5.366.
- Four-Factor Structure of Obsessive-Compulsive Disorder Symptoms in Children, Adolescents, and AdultsStewart SE, Rosario MC, Baer L, Carter AS, Brown TA, Scharf JM, Illmann C, Leckman JF, Sukhodolsky D, Katsovich L, Rasmussen S, Goodman W, Delorme R, Leboyer M, Chabane N, Jenike MA, Geller DA, Pauls DL. Four-Factor Structure of Obsessive-Compulsive Disorder Symptoms in Children, Adolescents, and Adults Journal Of The American Academy Of Child & Adolescent Psychiatry 2008, 47: 763-772. PMID: 18520961, DOI: 10.1097/chi.0b013e318172ef1e.
- Editorial: A global perspective on child and adolescent mental healthLeckman JF, Leventhal BL. Editorial: A global perspective on child and adolescent mental health Journal Of Child Psychology And Psychiatry 2008, 49: 221-225. PMID: 18333928, DOI: 10.1111/j.1469-7610.2008.01884.x.
- Oxytocin and cortisol in romantically unattached young adults: Associations with bonding and psychological distressGordon I, Zagoory‐Sharon O, Schneiderman I, Leckman JF, Weller A, Feldman R. Oxytocin and cortisol in romantically unattached young adults: Associations with bonding and psychological distress Psychophysiology 2008, 45: 349-352. PMID: 18266803, DOI: 10.1111/j.1469-8986.2008.00649.x.
- Genes Controlling Affiliative Behavior as Candidate Genes for AutismYrigollen CM, Han SS, Kochetkova A, Babitz T, Chang JT, Volkmar FR, Leckman JF, Grigorenko EL. Genes Controlling Affiliative Behavior as Candidate Genes for Autism Biological Psychiatry 2008, 63: 911-916. PMID: 18207134, PMCID: PMC2386897, DOI: 10.1016/j.biopsych.2007.11.015.
- Association of the serotonin transporter polymorphism and obsessive‐compulsive disorder: Systematic reviewBloch MH, Landeros‐Weisenberger A, Sen S, Dombrowski P, Kelmendi B, Coric V, Pittenger C, Leckman JF. Association of the serotonin transporter polymorphism and obsessive‐compulsive disorder: Systematic review American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2008, 147B: 850-858. PMID: 18186076, DOI: 10.1002/ajmg.b.30699.
- An Evolutionary and Developmental PerspectiveLeckman JF. An Evolutionary and Developmental Perspective Biological Psychiatry 2007, 62: 831-832. PMID: 17825798, PMCID: PMC2693705, DOI: 10.1016/j.biopsych.2007.07.006.
- A developmental perspective on the controversy surrounding the use of SSRIs to treat pediatric depression.Leckman JF, King RA. A developmental perspective on the controversy surrounding the use of SSRIs to treat pediatric depression. The American Journal Of Psychiatry 2007, 164: 1304-6. PMID: 17728409, DOI: 10.1176/appi.ajp.2007.07050880.
- Issues for DSM-V: How Should Obsessive-Compulsive and Related Disorders Be Classified?Mataix-Cols D, Pertusa A, Leckman JF. Issues for DSM-V: How Should Obsessive-Compulsive and Related Disorders Be Classified? American Journal Of Psychiatry 2007, 164: 1313-1314. PMID: 17728412, DOI: 10.1176/appi.ajp.2007.07040568.
- Systematic Review: Pharmacological and Behavioral Treatment for TrichotillomaniaBloch MH, Landeros-Weisenberger A, Dombrowski P, Kelmendi B, Wegner R, Nudel J, Pittenger C, Leckman JF, Coric V. Systematic Review: Pharmacological and Behavioral Treatment for Trichotillomania Biological Psychiatry 2007, 62: 839-846. PMID: 17727824, DOI: 10.1016/j.biopsych.2007.05.019.
- Repetitive Transcranial Magnetic Stimulation of the Supplementary Motor Area in the treatment of Tourette Syndrome: Report of two casesMantovani A, Leckman JF, Grantz H, King RA, Sporn AL, Lisanby SH. Repetitive Transcranial Magnetic Stimulation of the Supplementary Motor Area in the treatment of Tourette Syndrome: Report of two cases Clinical Neurophysiology 2007, 118: 2314-2315. PMID: 17709291, DOI: 10.1016/j.clinph.2007.07.011.
- Tourette Syndrome and Tic DisordersSwain JE, Scahill L, Lombroso PJ, King RA, Leckman JF. Tourette Syndrome and Tic Disorders Journal Of The American Academy Of Child & Adolescent Psychiatry 2007, 46: 947-968. PMID: 17667475, DOI: 10.1097/chi.0b013e318068fbcc.
- Obsessive-Compulsive Disorder: An Open-Label Pilot Trial of EscitalopramGalvão-de Almeida A, Quarantini LC, Góis CR, Santos-Jesus R, Miranda-Scippa AM, de Oliveira IR, da Silva Prado H, Leckman JF, Rosário MC. Obsessive-Compulsive Disorder: An Open-Label Pilot Trial of Escitalopram CNS Spectrums 2007, 12: 519-524. PMID: 17603402, DOI: 10.1017/s1092852900021258.
- Deep brain stimulation in Tourette's syndromeBajwa RJ, de Lotbinière AJ, King RA, Jabbari B, Quatrano S, Kunze K, Scahill L, Leckman JF. Deep brain stimulation in Tourette's syndrome Movement Disorders 2007, 22: 1346-1350. PMID: 17580320, DOI: 10.1002/mds.21398.
- The role of abnormal neural oscillations in the pathophysiology of co-occurring Tourette syndrome and attention-deficit/hyperactivity disorderSukhodolsky DG, Leckman JF, Rothenberger A, Scahill L. The role of abnormal neural oscillations in the pathophysiology of co-occurring Tourette syndrome and attention-deficit/hyperactivity disorder European Child & Adolescent Psychiatry 2007, 16: 51-59. PMID: 17665283, DOI: 10.1007/s00787-007-1007-3.
- Co-existence of tic disorders and attention-deficit/hyperactivity disorder-recent advances in understanding and treatmentRothenberger A, Roessner V, Banaschewski T, Leckman JF. Co-existence of tic disorders and attention-deficit/hyperactivity disorder-recent advances in understanding and treatment European Child & Adolescent Psychiatry 2007, 16: 1-4. PMID: 17665277, DOI: 10.1007/s00787-007-1001-9.
- Parental representations and subclinical changes in postpartum moodMayes LC, Leckman JF. Parental representations and subclinical changes in postpartum mood Infant Mental Health Journal 2007, 28: 281-295. PMID: 28640466, DOI: 10.1002/imhj.20136.
- Symptom Dimensions in Obsessive-Compulsive Disorder: Implications for the DSM-VLeckman JF, Rauch SL, Mataix-Cols D. Symptom Dimensions in Obsessive-Compulsive Disorder: Implications for the DSM-V CNS Spectrums 2007, 12: 376-387. PMID: 17514082, DOI: 10.1017/s1092852900021179.
- Gender differences in obsessive–compulsive symptom dimensionsLabad J, Menchon JM, Alonso P, Segalas C, Jimenez S, Jaurrieta N, Leckman JF, Vallejo J. Gender differences in obsessive–compulsive symptom dimensions Depression And Anxiety 2007, 25: 832-838. PMID: 17436312, DOI: 10.1002/da.20332.
- Nurturing resilient childrenLeckman JF, Mayes LC. Nurturing resilient children Journal Of Child Psychology And Psychiatry 2007, 48: 221-223. PMID: 17355396, DOI: 10.1111/j.1469-7610.2007.01743.x.
- Frontal dopaminergic abnormality in Tourette syndrome: A postmortem analysisYoon DY, Gause CD, Leckman JF, Singer HS. Frontal dopaminergic abnormality in Tourette syndrome: A postmortem analysis Journal Of The Neurological Sciences 2007, 255: 50-56. PMID: 17337006, DOI: 10.1016/j.jns.2007.01.069.
- Nurturing resilient childrenLeckman JF. Nurturing resilient children Brazilian Journal Of Psychiatry 2007, 29: 5-6. PMID: 17435918, DOI: 10.1590/s1516-44462007000100003.
- From Too Little Too Late to Early and Often: Child Psychiatry Education During Medical School (and Before and After)Martin A, Bloch M, Pruett K, Stubbe D, Belitsky R, Ebert M, Leckman JF. From Too Little Too Late to Early and Often: Child Psychiatry Education During Medical School (and Before and After) Child And Adolescent Psychiatric Clinics Of North America 2007, 16: 17-43. PMID: 17141116, DOI: 10.1016/j.chc.2006.07.005.
- Principal Components Analysis of Obsessive–Compulsive Disorder Symptoms in Children and AdolescentsStewart SE, Rosario MC, Brown TA, Carter AS, Leckman JF, Sukhodolsky D, Katsovitch L, King R, Geller D, Pauls DL. Principal Components Analysis of Obsessive–Compulsive Disorder Symptoms in Children and Adolescents Biological Psychiatry 2006, 61: 285-291. PMID: 17161383, DOI: 10.1016/j.biopsych.2006.08.040.
- Psychosocial stress predicts future symptom severities in children and adolescents with Tourette syndrome and/or obsessive‐compulsive disorderLin H, Katsovich L, Ghebremichael M, Findley DB, Grantz H, Lombroso PJ, King RA, Zhang H, Leckman JF. Psychosocial stress predicts future symptom severities in children and adolescents with Tourette syndrome and/or obsessive‐compulsive disorder Journal Of Child Psychology And Psychiatry 2006, 48: 157-166. PMID: 17300554, PMCID: PMC3073143, DOI: 10.1111/j.1469-7610.2006.01687.x.
- Patient selection and assessment recommendations for deep brain stimulation in Tourette syndromeMink JW, Walkup J, Frey KA, Como P, Cath D, DeLong MR, Erenberg G, Jankovic J, Juncos J, Leckman JF, Swerdlow N, Visser‐Vandewalle V, Vitek JL. Patient selection and assessment recommendations for deep brain stimulation in Tourette syndrome Movement Disorders 2006, 21: 1831-1838. PMID: 16991144, DOI: 10.1002/mds.21039.
- A Controlled Family Study of Attention-Deficit/Hyperactivity Disorder and Tourette's DisorderStewart SE, Illmann C, Geller DA, Leckman JF, King R, Pauls DL. A Controlled Family Study of Attention-Deficit/Hyperactivity Disorder and Tourette's Disorder Journal Of The American Academy Of Child & Adolescent Psychiatry 2006, 45: 1354-1362. PMID: 17075358, DOI: 10.1097/01.chi.0000251211.36868.fe.
- Identification of pyruvate kinase as an antigen associated with Tourette syndromeKansy JW, Katsovich L, McIver KS, Pick J, Zabriskie JB, Lombroso PJ, Leckman JF, Bibb JA. Identification of pyruvate kinase as an antigen associated with Tourette syndrome Journal Of Neuroimmunology 2006, 181: 165-176. PMID: 17011640, PMCID: PMC1853370, DOI: 10.1016/j.jneuroim.2006.08.007.
- Decreased Numbers of Regulatory T Cells Suggest Impaired Immune Tolerance in Children with Tourette Syndrome: A Preliminary StudyKawikova I, Leckman JF, Kronig H, Katsovich L, Bessen DE, Ghebremichael M, Bothwell AL. Decreased Numbers of Regulatory T Cells Suggest Impaired Immune Tolerance in Children with Tourette Syndrome: A Preliminary Study Biological Psychiatry 2006, 61: 273-278. PMID: 16996487, DOI: 10.1016/j.biopsych.2006.06.012.
- Tourette Syndrome: The Self Under SiegeLeckman JF, Bloch MH, Scahill L, King RA. Tourette Syndrome: The Self Under Siege Journal Of Child Neurology 2006, 21: 642-649. PMID: 16970864, DOI: 10.1177/08830738060210081001.
- A primary candidate gene for obsessive-compulsive disorder.Leckman JF, Kim YS. A primary candidate gene for obsessive-compulsive disorder. Archives Of General Psychiatry 2006, 63: 717-20. PMID: 16818860, DOI: 10.1001/archpsyc.63.7.717.
- Annotation: Tourette syndrome: a relentless drumbeat – driven by misguided brain oscillationsLeckman JF, Vaccarino FM, Kalanithi PS, Rothenberger A. Annotation: Tourette syndrome: a relentless drumbeat – driven by misguided brain oscillations Journal Of Child Psychology And Psychiatry 2006, 47: 537-550. PMID: 16712630, DOI: 10.1111/j.1469-7610.2006.01620.x.
- A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorderBloch MH, Landeros-Weisenberger A, Kelmendi B, Coric V, Bracken MB, Leckman JF. A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder Molecular Psychiatry 2006, 11: 622-632. PMID: 16585942, DOI: 10.1038/sj.mp.4001823.
- The normalcy of neurosis: Evolutionary origins of obsessive–compulsive disorder and related behaviorsFeygin DL, Swain JE, Leckman JF. The normalcy of neurosis: Evolutionary origins of obsessive–compulsive disorder and related behaviors Progress In Neuro-Psychopharmacology And Biological Psychiatry 2006, 30: 854-864. PMID: 16530315, DOI: 10.1016/j.pnpbp.2006.01.009.
- The Dimensional Yale–Brown Obsessive–Compulsive Scale (DY-BOCS): an instrument for assessing obsessive–compulsive symptom dimensionsRosario-Campos MC, Miguel EC, Quatrano S, Chacon P, Ferrao Y, Findley D, Katsovich L, Scahill L, King RA, Woody SR, Tolin D, Hollander E, Kano Y, Leckman JF. The Dimensional Yale–Brown Obsessive–Compulsive Scale (DY-BOCS): an instrument for assessing obsessive–compulsive symptom dimensions Molecular Psychiatry 2006, 11: 495-504. PMID: 16432526, DOI: 10.1038/sj.mp.4001798.
- Adulthood Outcome of Tic and Obsessive-Compulsive Symptom Severity in Children With Tourette SyndromeBloch MH, Peterson BS, Scahill L, Otka J, Katsovich L, Zhang H, Leckman JF. Adulthood Outcome of Tic and Obsessive-Compulsive Symptom Severity in Children With Tourette Syndrome JAMA Pediatrics 2006, 160: 65-69. PMID: 16389213, PMCID: PMC2291298, DOI: 10.1001/archpedi.160.1.65.
- Phenomenology of tics and natural history of tic disorders.Leckman JF, Bloch MH, King RA, Scahill L. Phenomenology of tics and natural history of tic disorders. Advances In Neurology 2006, 99: 1-16. PMID: 16536348.
- Disruptive behavior problems in a community sample of children with tic disorders.Scahill L, Williams S, Schwab-Stone M, Applegate J, Leckman JF. Disruptive behavior problems in a community sample of children with tic disorders. Advances In Neurology 2006, 99: 184-90. PMID: 16536365.
- Fine‐motor skill deficits in childhood predict adulthood tic severity and global psychosocial functioning in Tourette's syndromeBloch MH, Sukhodolsky DG, Leckman JF, Schultz RT. Fine‐motor skill deficits in childhood predict adulthood tic severity and global psychosocial functioning in Tourette's syndrome Journal Of Child Psychology And Psychiatry 2005, 47: 551-559. PMID: 16712631, DOI: 10.1111/j.1469-7610.2005.01561.x.
- The wolf boy: reactive attachment disorder in an adolescent boy.Swain JE, Leckman JF, Volkmar FR. The wolf boy: reactive attachment disorder in an adolescent boy. Innov Clin Neurosci 2005, 2: 55-61. PMID: 21120097, PMCID: PMC2993525.
- Caudate volumes in childhood predict symptom severity in adults with Tourette syndromeBloch MH, Leckman JF, Zhu H, Peterson BS. Caudate volumes in childhood predict symptom severity in adults with Tourette syndrome Neurology 2005, 65: 1253-1258. PMID: 16247053, PMCID: PMC2367161, DOI: 10.1212/01.wnl.0000180957.98702.69.
- Sequence Variants in SLITRK1 Are Associated with Tourette's SyndromeAbelson JF, Kwan KY, O'Roak BJ, Baek DY, Stillman AA, Morgan TM, Mathews CA, Pauls DL, Rašin M, Gunel M, Davis NR, Ercan-Sencicek AG, Guez DH, Spertus JA, Leckman JF, Dure LS, Kurlan R, Singer HS, Gilbert DL, Farhi A, Louvi A, Lifton RP, Šestan N, State MW. Sequence Variants in SLITRK1 Are Associated with Tourette's Syndrome Science 2005, 310: 317-320. PMID: 16224024, DOI: 10.1126/science.1116502.
- Antineural antibody in patients with Tourette’s syndrome and their family membersYeh CB, Wu CH, Tsung HC, Chen CW, Shyu JF, Leckman JF. Antineural antibody in patients with Tourette’s syndrome and their family members Journal Of Biomedical Science 2005, 13: 101-112. PMID: 16215701, DOI: 10.1007/s11373-005-9033-y.
- Altered parvalbumin-positive neuron distribution in basal ganglia of individuals with Tourette syndromeKalanithi PS, Zheng W, Kataoka Y, DiFiglia M, Grantz H, Saper CB, Schwartz ML, Leckman JF, Vaccarino FM. Altered parvalbumin-positive neuron distribution in basal ganglia of individuals with Tourette syndrome Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 13307-13312. PMID: 16131542, PMCID: PMC1201574, DOI: 10.1073/pnas.0502624102.
- A family study of early‐onset obsessive‐compulsive disorderdo Rosario‐Campos M, Leckman JF, Curi M, Quatrano S, Katsovitch L, Miguel EC, Pauls DL. A family study of early‐onset obsessive‐compulsive disorder American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2005, 136B: 92-97. PMID: 15892140, DOI: 10.1002/ajmg.b.30149.
- Tourette syndrome and tic disorders: overview and practical guide to diagnosis and treatment.Swain JE, Leckman JF. Tourette syndrome and tic disorders: overview and practical guide to diagnosis and treatment. Innov Clin Neurosci 2005, 2: 26-36. PMID: 21152158, PMCID: PMC3000195.
- Adaptive, Emotional, and Family Functioning of Children With Obsessive-Compulsive Disorder and Comorbid Attention Deficit Hyperactivity DisorderSukhodolsky DG, do Rosario-Campos MC, Scahill L, Katsovich L, Pauls DL, Peterson BS, King RA, Lombroso PJ, Findley DB, Leckman JF. Adaptive, Emotional, and Family Functioning of Children With Obsessive-Compulsive Disorder and Comorbid Attention Deficit Hyperactivity Disorder American Journal Of Psychiatry 2005, 162: 1125-1132. PMID: 15930061, PMCID: PMC2291297, DOI: 10.1176/appi.ajp.162.6.1125.
- Microinfusion of antineuronal antibodies into rodent striatum: Failure to differentiate between elevated and low titersSinger HS, Mink JW, Loiselle CR, Burke KA, Ruchkina I, Morshed S, Parveen S, Leckman JF, Hallett JJ, Lombroso PJ. Microinfusion of antineuronal antibodies into rodent striatum: Failure to differentiate between elevated and low titers Journal Of Neuroimmunology 2005, 163: 8-14. PMID: 15885303, DOI: 10.1016/j.jneuroim.2005.02.018.
- Increased serum levels of interleukin-12 and tumor necrosis factor-alpha in Tourette’s syndromeLeckman JF, Katsovich L, Kawikova I, Lin H, Zhang H, Krönig H, Morshed S, Parveen S, Grantz H, Lombroso PJ, King RA. Increased serum levels of interleukin-12 and tumor necrosis factor-alpha in Tourette’s syndrome Biological Psychiatry 2005, 57: 667-673. PMID: 15780855, DOI: 10.1016/j.biopsych.2004.12.004.
- Sudden death in a patient with Tourette syndrome during a clinical trial of ziprasidoneScahill L, Blair J, Leckman JF, Martin A. Sudden death in a patient with Tourette syndrome during a clinical trial of ziprasidone Journal Of Psychopharmacology 2005, 19: 205-206. PMID: 15728441, DOI: 10.1177/0269881105049042.
- A Multidimensional Model of Obsessive-Compulsive DisorderMataix-Cols D, Rosario-Campos MC, Leckman JF. A Multidimensional Model of Obsessive-Compulsive Disorder American Journal Of Psychiatry 2005, 162: 228-238. PMID: 15677583, DOI: 10.1176/appi.ajp.162.2.228.
- Public health significance of tic disorders in children and adolescents.Scahill L, Sukhodolsky DG, Williams SK, Leckman JF. Public health significance of tic disorders in children and adolescents. Advances In Neurology 2005, 96: 240-8. PMID: 16383223.
- Antidepressant-induced manic conversion: a developmentally informed synthesis of the literature.Lim CJ, Leckman JF, Young C, Martin A. Antidepressant-induced manic conversion: a developmentally informed synthesis of the literature. International Review Of Neurobiology 2005, 65: 25-52. PMID: 16140052, DOI: 10.1016/S0074-7742(04)65002-1.
- Obsessive-compulsive disorder phenotypes: implications for genetic studiesMiguel EC, Leckman JF, Rauch S, do Rosario-Campos MC, Hounie AG, Mercadante MT, Chacon P, Pauls DL. Obsessive-compulsive disorder phenotypes: implications for genetic studies Molecular Psychiatry 2004, 10: 258-275. PMID: 15611786, DOI: 10.1038/sj.mp.4001617.
- Linkage analysis of ordinal traits for pedigree dataFeng R, Leckman JF, Zhang H. Linkage analysis of ordinal traits for pedigree data Proceedings Of The National Academy Of Sciences Of The United States Of America 2004, 101: 16739-16744. PMID: 15548606, PMCID: PMC534720, DOI: 10.1073/pnas.0404623101.
- Altered Interhemispheric Connectivity in Individuals With Tourettes DisorderPlessen KJ, Wentzel-Larsen T, Hugdahl K, Feineigle P, Klein J, Staib LH, Leckman JF, Bansal R, Peterson BS. Altered Interhemispheric Connectivity in Individuals With Tourettes Disorder American Journal Of Psychiatry 2004, 161: 2028-2037. PMID: 15514403, DOI: 10.1176/appi.ajp.161.11.2028.
- Age Effects on Antidepressant-Induced Manic ConversionMartin A, Young C, Leckman JF, Mukonoweshuro C, Rosenheck R, Leslie D. Age Effects on Antidepressant-Induced Manic Conversion JAMA Pediatrics 2004, 158: 773-780. PMID: 15289250, DOI: 10.1001/archpedi.158.8.773.
- Obsessive‐compulsive symptoms in parents of Tourette syndrome probands and autism spectrum disorder probandsKANO Y, OHTA M, NAGAI Y, PAULS DL, LECKMAN JF. Obsessive‐compulsive symptoms in parents of Tourette syndrome probands and autism spectrum disorder probands Psychiatry And Clinical Neurosciences 2004, 58: 348-352. PMID: 15298645, DOI: 10.1111/j.1440-1819.2004.01266.x.
- Prospective Longitudinal Study of Children With Tic Disorders and/or Obsessive-Compulsive Disorder: Relationship of Symptom Exacerbations to Newly Acquired Streptococcal InfectionsLuo F, Leckman JF, Katsovich L, Findley D, Grantz H, Tucker DM, Lombroso PJ, King RA, Bessen DE. Prospective Longitudinal Study of Children With Tic Disorders and/or Obsessive-Compulsive Disorder: Relationship of Symptom Exacerbations to Newly Acquired Streptococcal Infections Pediatrics 2004, 113: e578-e585. PMID: 15173540, DOI: 10.1542/peds.113.6.e578.
- Primary parental preoccupation: circuits, genes, and the crucial role of the environmentLeckman JF, Feldman R, Swain JE, Eicher V, Thompson N, Mayes LC. Primary parental preoccupation: circuits, genes, and the crucial role of the environment Journal Of Neural Transmission 2004, 111: 753-771. PMID: 15205997, DOI: 10.1007/s00702-003-0067-x.
- Expression of BEN, a member of TFII-I family of transcription factors, during mouse pre- and postimplantation developmentBayarsaihan D, Bitchevaia N, Enkhmandakh B, Tussie-Luna MI, Leckman JF, Roy A, Ruddle F. Expression of BEN, a member of TFII-I family of transcription factors, during mouse pre- and postimplantation development Gene Expression Patterns 2003, 3: 579-589. PMID: 12971990, DOI: 10.1016/s1567-133x(03)00118-2.
- Homez, a homeobox leucine zipper gene specific to the vertebrate lineageBayarsaihan D, Enkhmandakh B, Makeyev A, Greally JM, Leckman JF, Ruddle FH. Homez, a homeobox leucine zipper gene specific to the vertebrate lineage Proceedings Of The National Academy Of Sciences Of The United States Of America 2003, 100: 10358-10363. PMID: 12925734, PMCID: PMC193566, DOI: 10.1073/pnas.1834010100.
- Tourette’s syndrome in childrenSwain JE, Leckman JF. Tourette’s syndrome in children Current Treatment Options In Neurology 2003, 5: 299-308. PMID: 12791197, DOI: 10.1007/s11940-003-0036-6.
- Influence of Age and Tic Disorders on Obsessive-Compulsive Disorder in a Pediatric SampleScahill L, Kano Y, King RA, Carlson A, Peller A, LeBrun U, do Rosario-Campos MC, Leckman JF. Influence of Age and Tic Disorders on Obsessive-Compulsive Disorder in a Pediatric Sample Journal Of Child And Adolescent Psychopharmacology 2003, 13: 7-17. PMID: 12880496, DOI: 10.1089/104454603322126304.
- A placebo-controlled trial of risperidone in Tourette syndromeScahill L, Leckman JF, Schultz RT, Katsovich L, Peterson BS. A placebo-controlled trial of risperidone in Tourette syndrome Neurology 2003, 60: 1130-1135. PMID: 12682319, DOI: 10.1212/01.wnl.0000055434.39968.67.
- Epigenetic abnormalities associated with a chromosome 18(q21-q22) inversion and a Gilles de la Tourette syndrome phenotypeState MW, Greally JM, Cuker A, Bowers PN, Henegariu O, Morgan TM, Gunel M, DiLuna M, King RA, Nelson C, Donovan A, Anderson GM, Leckman JF, Hawkins T, Pauls DL, Lifton RP, Ward DC. Epigenetic abnormalities associated with a chromosome 18(q21-q22) inversion and a Gilles de la Tourette syndrome phenotype Proceedings Of The National Academy Of Sciences Of The United States Of America 2003, 100: 4684-4689. PMID: 12682296, PMCID: PMC153616, DOI: 10.1073/pnas.0730775100.
- Development of the Yale Children’s Global Stress Index (YCGSI) and Its Application in Children and Adolescents With Tourette’s Syndrome and Obsessive-Compulsive DisorderFINDLEY DB, LECKMAN JF, KATSOVICH L, LIN H, ZHANG H, GRANTZ H, OTKA J, LOMBROSO PJ, KING RA. Development of the Yale Children’s Global Stress Index (YCGSI) and Its Application in Children and Adolescents With Tourette’s Syndrome and Obsessive-Compulsive Disorder Journal Of The American Academy Of Child & Adolescent Psychiatry 2003, 42: 450-457. PMID: 12649632, DOI: 10.1097/01.chi.0000046816.95464.ef.
- Basal Ganglia Volumes in Patients With Gilles de la Tourette SyndromePeterson BS, Thomas P, Kane MJ, Scahill L, Zhang H, Bronen R, King RA, Leckman JF, Staib L. Basal Ganglia Volumes in Patients With Gilles de la Tourette Syndrome JAMA Psychiatry 2003, 60: 415-424. PMID: 12695320, DOI: 10.1001/archpsyc.60.4.415.
- Obsessions and compulsions in anorexia nervosa subtypesHalmi KA, Sunday SR, Klump KL, Strober M, Leckman JF, Fichter M, Kaplan A, Woodside B, Treasure J, Berrettini WH, Shabboat M, Bulik CM, Kaye WH. Obsessions and compulsions in anorexia nervosa subtypes International Journal Of Eating Disorders 2003, 33: 308-319. PMID: 12655628, DOI: 10.1002/eat.10138.
- Disruptive Behavior in Children With Tourette’s Syndrome: Association With ADHD Comorbidity, Tic Severity, and Functional ImpairmentSUKHODOLSKY DG, SCAHILL L, ZHANG H, PETERSON BS, KING RA, LOMBROSO PJ, KATSOVICH L, FINDLEY D, LECKMAN JF. Disruptive Behavior in Children With Tourette’s Syndrome: Association With ADHD Comorbidity, Tic Severity, and Functional Impairment Journal Of The American Academy Of Child & Adolescent Psychiatry 2003, 42: 98-105. PMID: 12500082, DOI: 10.1097/00004583-200301000-00016.
- Phenomenology of tics and natural history of tic disordersLeckman JF. Phenomenology of tics and natural history of tic disorders Brain And Development 2003, 25: s24-s28. PMID: 14980368, DOI: 10.1016/s0387-7604(03)90004-0.
- Obsessive‐compulsive symptom dimensions in affected sibling pairs diagnosed with Gilles de la Tourette syndromeLeckman JF, Pauls DL, Zhang H, Rosario‐Campos M, Katsovich L, Kidd KK, Pakstis AJ, Alsobrook JP, Robertson MM, McMahon WM, Walkup JT, van de Wetering BJ, King RA, Cohen DJ. Obsessive‐compulsive symptom dimensions in affected sibling pairs diagnosed with Gilles de la Tourette syndrome American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2002, 116B: 60-68. PMID: 12497616, DOI: 10.1002/ajmg.b.10001.
- Tourette's syndromeLeckman JF. Tourette's syndrome The Lancet 2002, 360: 1577-1586. PMID: 12443611, DOI: 10.1016/s0140-6736(02)11526-1.
- CLINICAL CHARACTERISTICS OF TOURETTE SYNDROME PROBANDS AND RELATIVES’ RISKSKano Y, Leckman JF, Pauls DL. CLINICAL CHARACTERISTICS OF TOURETTE SYNDROME PROBANDS AND RELATIVES’ RISKS Journal Of The American Academy Of Child & Adolescent Psychiatry 2002, 41: 1148-1149. PMID: 12364837, DOI: 10.1097/00004583-200210000-00005.
- Assessment of Symptom Exacerbations in a Longitudinal Study of Children With Tourette’s Syndrome or Obsessive-Compulsive DisorderLIN H, YEH CB, PETERSON BS, SCAHILL L, GRANTZ H, FINDLEY DB, KATSOVICH L, OTKA J, LOMBROSO PJ, KING RA, LECKMAN JF. Assessment of Symptom Exacerbations in a Longitudinal Study of Children With Tourette’s Syndrome or Obsessive-Compulsive Disorder Journal Of The American Academy Of Child & Adolescent Psychiatry 2002, 41: 1070-1077. PMID: 12218428, DOI: 10.1097/00004583-200209000-00007.
- Development and natural history of mood disordersCostello EJ, Pine DS, Hammen C, March JS, Plotsky PM, Weissman MM, Biederman J, Goldsmith HH, Kaufman J, Lewinsohn PM, Hellander M, Hoagwood K, Koretz DS, Nelson CA, Leckman JF. Development and natural history of mood disorders Biological Psychiatry 2002, 52: 529-542. PMID: 12361667, DOI: 10.1016/s0006-3223(02)01372-0.
- Characteristics of acute stress symptoms and nitric oxide concentration in young rescue workers in TaiwanYeh CB, Leckman J, Wan FJ, Shiah IS, Lu RB. Characteristics of acute stress symptoms and nitric oxide concentration in young rescue workers in Taiwan Psychiatry Research 2002, 112: 59-68. PMID: 12379451, DOI: 10.1016/s0165-1781(02)00179-8.
- Obsessive-compulsive disorders in children. Subtypes of OCD and their relation to infection with group A streptococci.Thomsen PH, Leckman J. Obsessive-compulsive disorders in children. Subtypes of OCD and their relation to infection with group A streptococci. Ugeskrift For Laeger 2002, 164: 3763-7. PMID: 12362609.
- Treatment non-response in OCD: methodological issues and operational definitionsPallanti S, Hollander E, Bienstock C, Koran L, Leckman J, Marazziti D, Pato M, Stein D, Zohar J. Treatment non-response in OCD: methodological issues and operational definitions The International Journal Of Neuropsychopharmacology 2002, 5: 181-191. PMID: 12135542, DOI: 10.1017/s1461145702002900.
- An Animal Model of Tourettes SyndromeTaylor JR, Morshed SA, Parveen S, Mercadante MT, Scahill L, Peterson BS, King RA, Leckman JF, Lombroso PJ. An Animal Model of Tourettes Syndrome American Journal Of Psychiatry 2002, 159: 657-660. PMID: 11925307, DOI: 10.1176/appi.ajp.159.4.657.
- Genomewide Scan of Hoarding in Sib Pairs in Which Both Sibs Have Gilles de la Tourette SyndromeZhang H, Leckman JF, Pauls DL, Tsai CP, Kidd KK, Campos MR, Genetics T. Genomewide Scan of Hoarding in Sib Pairs in Which Both Sibs Have Gilles de la Tourette Syndrome American Journal Of Human Genetics 2002, 70: 896-904. PMID: 11840360, PMCID: PMC379118, DOI: 10.1086/339520.
- Maternal behavior and developmental psychopathologyLeckman JF, Herman AE. Maternal behavior and developmental psychopathology Biological Psychiatry 2002, 51: 27-43. PMID: 11801229, DOI: 10.1016/s0006-3223(01)01277-x.
- Tic disorders: when habit forming neural systems form habits of their own?Leckman JF, Yeh CB, Cohen DJ. Tic disorders: when habit forming neural systems form habits of their own? Journal Of The Chinese Medical Association 2001, 64: 669-92. PMID: 11922487.
- Adults With Early-Onset Obsessive-Compulsive DisorderRosario-Campos MC, Leckman JF, Mercadante MT, Shavitt RG, Prado HS, Sada P, Zamignani D, Miguel EC. Adults With Early-Onset Obsessive-Compulsive Disorder American Journal Of Psychiatry 2001, 158: 1899-1903. PMID: 11691698, DOI: 10.1176/appi.ajp.158.11.1899.
- A Placebo-Controlled Study of Guanfacine in the Treatment of Children With Tic Disorders and Attention Deficit Hyperactivity DisorderScahill L, Chappell PB, Kim YS, Schultz RT, Katsovich L, Shepherd E, Arnsten AF, Cohen DJ, Leckman JF. A Placebo-Controlled Study of Guanfacine in the Treatment of Children With Tic Disorders and Attention Deficit Hyperactivity Disorder American Journal Of Psychiatry 2001, 158: 1067-1074. PMID: 11431228, DOI: 10.1176/appi.ajp.158.7.1067.
- Regional Brain and Ventricular Volumes in Tourette SyndromePeterson BS, Staib L, Scahill L, Zhang H, Anderson C, Leckman JF, Cohen DJ, Gore JC, Albert J, Webster R. Regional Brain and Ventricular Volumes in Tourette Syndrome JAMA Psychiatry 2001, 58: 427-440. PMID: 11343521, DOI: 10.1001/archpsyc.58.5.427.
- Phenomenology of tics and natural history of tic disorders.Leckman JF, Peterson BS, King RA, Scahill L, Cohen DJ. Phenomenology of tics and natural history of tic disorders. Advances In Neurology 2001, 85: 1-14. PMID: 11530419.
- Tourette syndrome: pieces of the puzzle.Leckman JF, Cohen DJ, Goetz CG, Jankovic J. Tourette syndrome: pieces of the puzzle. Advances In Neurology 2001, 85: 369-90. PMID: 11530445.
- The Psychiatric Symptoms of Rheumatic FeverMercadante MT, Busatto GF, Lombroso PJ, Prado L, Rosário-Campos MC, do Valle R, Marques-Dias MJ, Kiss MH, Leckman JF, Miguel EC. The Psychiatric Symptoms of Rheumatic Fever American Journal Of Psychiatry 2000, 157: 2036-2038. PMID: 11097972, DOI: 10.1176/appi.ajp.157.12.2036.
- Preliminary Findings of Antistreptococcal Antibody Titers and Basal Ganglia Volumes in Tic, Obsessive-compulsive, and Attention-Deficit/Hyperactivity DisordersPeterson BS, Leckman JF, Tucker D, Scahill L, Staib L, Zhang H, King R, Cohen DJ, Gore JC, Lombroso P. Preliminary Findings of Antistreptococcal Antibody Titers and Basal Ganglia Volumes in Tic, Obsessive-compulsive, and Attention-Deficit/Hyperactivity Disorders JAMA Psychiatry 2000, 57: 364-372. PMID: 10768698, DOI: 10.1001/archpsyc.57.4.364.
- Sensory phenomena in obsessive-compulsive disorder and Tourette's disorder.Miguel EC, do Rosário-Campos MC, Prado HS, do Valle R, Rauch SL, Coffey BJ, Baer L, Savage CR, O'Sullivan RL, Jenike MA, Leckman JF. Sensory phenomena in obsessive-compulsive disorder and Tourette's disorder. The Journal Of Clinical Psychiatry 2000, 61: 150-6; quiz 157. PMID: 10732667, DOI: 10.4088/jcp.v61n0213.
- Risperidone-Associated Weight Gain in Children and Adolescents: A Retrospective Chart ReviewMartin A, Landau J, Leebens P, Ulizio K, Cicchetti D, Scahill L, Leckman JF. Risperidone-Associated Weight Gain in Children and Adolescents: A Retrospective Chart Review Journal Of Child And Adolescent Psychopharmacology 2000, 10: 259-268. PMID: 11191686, DOI: 10.1089/cap.2000.10.259.
- Developmental psychopathology: research, clinical care and social policy.Cohen DJ, Leckman JF. Developmental psychopathology: research, clinical care and social policy. The Israel Journal Of Psychiatry And Related Sciences 2000, 37: 162-4. PMID: 11084803.
- The Tourette Syndrome Diagnostic Confidence IndexRobertson MM, Banerjee S, Kurlan R, Cohen DJ, Leckman JF, McMahon W, Pauls DL, Sandor P, van de Wetering B. The Tourette Syndrome Diagnostic Confidence Index Neurology 1999, 53: 2108-2112. PMID: 10599790, DOI: 10.1212/wnl.53.9.2108.
- Incremental progress in developmental psychopathology: simply complex.Leckman JF. Incremental progress in developmental psychopathology: simply complex. The American Journal Of Psychiatry 1999, 156: 1495-8. PMID: 10518156, DOI: 10.1176/ajp.156.10.1495.
- Early parental preoccupations and behaviors and their possible relationship to the symptoms of obsessive‐compulsive disorderLeckman JF, Mayes LC, Feldman R, Evans DW, King RA, Cohen DJ. Early parental preoccupations and behaviors and their possible relationship to the symptoms of obsessive‐compulsive disorder Acta Psychiatrica Scandinavica. Supplementum. 1999, 100: 1-26. PMID: 10478283, DOI: 10.1111/j.1600-0447.1999.tb10951.x.
- Cerebrospinal fluid dynorphin A[1-8] and beta-endorphin levels in Tourette's syndrome are unaltered.van Wattum PJ, Anderson GM, Chappell PB, Goodman WK, Riddle MA, Leckman JF. Cerebrospinal fluid dynorphin A[1-8] and beta-endorphin levels in Tourette's syndrome are unaltered. Biological Psychiatry 1999, 45: 1527-8. PMID: 10356639.
- Oxytocin, vasopressin, and autism: is there a connection?Insel TR, O'Brien DJ, Leckman JF. Oxytocin, vasopressin, and autism: is there a connection? Biological Psychiatry 1999, 45: 145-57. PMID: 9951561, DOI: 10.1016/s0006-3223(98)00142-5.
- Prader-Willi SyndromeMartin A, State M, Koenig K, Schultz R, Dykens EM, Cassidy SB, Leckman JF. Prader-Willi Syndrome American Journal Of Psychiatry 1998, 155: 1265-1273. PMID: 9734553, DOI: 10.1176/ajp.155.9.1265.
- A Functional Magnetic Resonance Imaging Study of Tic Suppression in Tourette SyndromePeterson BS, Skudlarski P, Anderson AW, Zhang H, Gatenby JC, Lacadie CM, Leckman JF, Gore JC. A Functional Magnetic Resonance Imaging Study of Tic Suppression in Tourette Syndrome JAMA Psychiatry 1998, 55: 326-333. PMID: 9554428, DOI: 10.1001/archpsyc.55.4.326.
- Visual–Motor Integration Functioning in Children With Tourette SyndromeSchultz RT, Carter AS, Gladstone M, Scahill L, Leckman JF, Peterson BS, Zhang H, Cohen DJ, Pauls D. Visual–Motor Integration Functioning in Children With Tourette Syndrome Neuropsychology 1998, 12: 134-145. PMID: 9460741, DOI: 10.1037/0894-4105.12.1.134.
- Symptoms of obsessive-compulsive disorderLeckman JF, Grice DE, Boardman J, Zhang H, Vitale A, Bondi C, Alsobrook J, Peterson BS, Cohen DJ, Rasmussen SA, Goodman WK, McDougle CJ, Pauls DL. Symptoms of obsessive-compulsive disorder American Journal Of Psychiatry 1997, 154: 911-917. PMID: 9210740, DOI: 10.1176/ajp.154.7.911.
- FUTURE THERAPIES OF TOURETTE SYNDROME * *Portions of this article have previously appeared in Chappell PB, Leckman JF, Riddle MA: The pharmacologic treatment of tic disorders. Child Adolesc Psychiatr Clin North Am. 4:197, 1995.Chappell PB, Scahill LD, Leckman JF. FUTURE THERAPIES OF TOURETTE SYNDROME * *Portions of this article have previously appeared in Chappell PB, Leckman JF, Riddle MA: The pharmacologic treatment of tic disorders. Child Adolesc Psychiatr Clin North Am. 4:197, 1995. Neurologic Clinics 1997, 15: 429-450. PMID: 9115473, DOI: 10.1016/s0733-8619(05)70324-8.
- Obsessive-compulsive disorder with and without tics in an epidemiological sample of adolescentsZohar AH, Pauls DL, Ratzoni G, Apter A, Dycian A, Binder M, King R, Leckman JF, Kron S, Cohen DJ. Obsessive-compulsive disorder with and without tics in an epidemiological sample of adolescents American Journal Of Psychiatry 1997, 154: 274-276. PMID: 9016283, DOI: 10.1176/ajp.154.2.274.
- Fluoxetine Has No Marked Effect on Tic Symptoms in Patients with Tourette's Syndrome: A Double-Blind Placebo-Controlled StudyScahill L, Riddle MA, King RA, Hardin MT, Rasmusson A, Makuch RW, Leckman JF. Fluoxetine Has No Marked Effect on Tic Symptoms in Patients with Tourette's Syndrome: A Double-Blind Placebo-Controlled Study Journal Of Child And Adolescent Psychopharmacology 1997, 7: 75-85. PMID: 9334893, DOI: 10.1089/cap.1997.7.75.
- Linkage disequilibrium between an allele at the dopamine D4 receptor locus and Tourette syndrome, by the transmission-disequilibrium test.Grice DE, Leckman JF, Pauls DL, Kurlan R, Kidd KK, Pakstis AJ, Chang FM, Buxbaum JD, Cohen DJ, Gelernter J. Linkage disequilibrium between an allele at the dopamine D4 receptor locus and Tourette syndrome, by the transmission-disequilibrium test. American Journal Of Human Genetics 1996, 59: 644-52. PMID: 8751866, PMCID: PMC1914894.
- Risperidone addition in fluvoxamine-refractory obsessive-compulsive disorder: three cases.McDougle CJ, Fleischmann RL, Epperson CN, Wasylink S, Leckman JF, Price LH. Risperidone addition in fluvoxamine-refractory obsessive-compulsive disorder: three cases. The Journal Of Clinical Psychiatry 1995, 56: 526-8. PMID: 7592506.
- [123I]beta-CIT SPECT imaging of striatal dopamine transporter binding in Tourette's disorderMalison RT, McDougle CJ, van Dyck CH, Scahill L, Baldwin RM, Seibyl JP, Price LH, Leckman JF, Innis RB. [123I]beta-CIT SPECT imaging of striatal dopamine transporter binding in Tourette's disorder American Journal Of Psychiatry 1995, 152: 1359-1361. PMID: 7653693, DOI: 10.1176/ajp.152.9.1359.
- Basic fibroblast growth factor increases the number of excitatory neurons containing glutamate in the cerebral cortex.Vaccarino FM, Schwartz ML, Hartigan D, Leckman JF. Basic fibroblast growth factor increases the number of excitatory neurons containing glutamate in the cerebral cortex. Cerebral Cortex 1995, 5: 64-78. PMID: 7719131, DOI: 10.1093/cercor/5.1.64.
- A family study of obsessive-compulsive disorderPauls DL, Alsobrook JP, Goodman W, Rasmussen S, Leckman JF. A family study of obsessive-compulsive disorder American Journal Of Psychiatry 1995, 152: 76-84. PMID: 7802125, DOI: 10.1176/ajp.152.1.76.
- Sensory phenomena in Tourette's syndrome.Scahill LD, Leckman JF, Marek KL. Sensory phenomena in Tourette's syndrome. Advances In Neurology 1995, 65: 273-80. PMID: 7872145.
- Tourette's syndrome: a multigenerational, neuropsychiatric disorder.Lombroso PJ, Scahill LD, Chappell PB, Pauls DL, Cohen DJ, Leckman JF. Tourette's syndrome: a multigenerational, neuropsychiatric disorder. Advances In Neurology 1995, 65: 305-18. PMID: 7872149.
- "Just right" perceptions associated with compulsive behavior in Tourette's syndromeLeckman JF, Walker DE, Goodman WK, Pauls DL, Cohen DJ. "Just right" perceptions associated with compulsive behavior in Tourette's syndrome American Journal Of Psychiatry 1994, 151: 675-680. PMID: 8166308, DOI: 10.1176/ajp.151.5.675.
- D2 Dopamine Receptor Alleles Do Not Influence Severity of Tourette's Syndrome: Results From Four Large KindredsGelernter J, Pauls DL, Leckman J, Kidd KK, Kurlan R. D2 Dopamine Receptor Alleles Do Not Influence Severity of Tourette's Syndrome: Results From Four Large Kindreds JAMA Neurology 1994, 51: 397-400. PMID: 8155017, DOI: 10.1001/archneur.1994.00540160099012.
- Haloperidol Addition in Fluvoxamine-Refractory Obsessive-Compulsive Disorder: A Double-blind, Placebo-Controlled Study in Patients With and Without TicsMcDougle CJ, Goodman WK, Leckman JF, Lee NC, Heninger GR, Price LH. Haloperidol Addition in Fluvoxamine-Refractory Obsessive-Compulsive Disorder: A Double-blind, Placebo-Controlled Study in Patients With and Without Tics JAMA Psychiatry 1994, 51: 302-308. PMID: 8161290, DOI: 10.1001/archpsyc.1994.03950040046006.
- Severe disturbances in speech, swallowing, and gait following stereotactic infrathalamic lesions in Gilles de la Tourette's syndrome.Leckman JF, de Lotbinière AJ, Marek K, Gracco C, Scahill L, Cohen DJ. Severe disturbances in speech, swallowing, and gait following stereotactic infrathalamic lesions in Gilles de la Tourette's syndrome. Neurology 1993, 43: 890-4. PMID: 8492943, DOI: 10.1212/wnl.43.5.890.
- Reduced basal ganglia volumes in Tourette's syndrome using three-dimensional reconstruction techniques from magnetic resonance images.Peterson B, Riddle MA, Cohen DJ, Katz LD, Smith JC, Hardin MT, Leckman JF. Reduced basal ganglia volumes in Tourette's syndrome using three-dimensional reconstruction techniques from magnetic resonance images. Neurology 1993, 43: 941-9. PMID: 8492950, DOI: 10.1212/wnl.43.5.941.
- Limited therapeutic effect of addition of buspirone in fluvoxamine- refractory obsessive-compulsive disorderMcDougle CJ, Goodman WK, Leckman JF, Holzer JC, Barr LC, McCance-Katz E, Heninger GR, Price LH. Limited therapeutic effect of addition of buspirone in fluvoxamine- refractory obsessive-compulsive disorder American Journal Of Psychiatry 1993, 150: 647-649. PMID: 8465885, DOI: 10.1176/ajp.150.4.647.
- Premonitory urges in Tourette's syndromeLeckman JF, Walker DE, Cohen DJ. Premonitory urges in Tourette's syndrome American Journal Of Psychiatry 1993, 150: 98-102. PMID: 8417589, DOI: 10.1176/ajp.150.1.98.
- Sensory phenomena associated with Gilles de la Tourette's syndrome.Cohen AJ, Leckman JF. Sensory phenomena associated with Gilles de la Tourette's syndrome. The Journal Of Clinical Psychiatry 1992, 53: 319-23. PMID: 1517194.
- Tourette's syndrome.Leckman JF. Tourette's syndrome. New Directions For Mental Health Services 1992, 29-33. PMID: 1352621, DOI: 10.1002/yd.23319925407.
- K-ABC profiles in children with fragile X syndrome, Down syndrome, and nonspecific mental retardation.Hodapp RM, Leckman JF, Dykens EM, Sparrow SS, Zelinsky DG, Ort SI. K-ABC profiles in children with fragile X syndrome, Down syndrome, and nonspecific mental retardation. American Journal On Intellectual And Developmental Disabilities 1992, 97: 39-46. PMID: 1386742.
- Postmortem analysis of subcortical monoamines and amino acids in Tourette syndrome.Anderson GM, Pollak ES, Chatterjee D, Leckman JF, Riddle MA, Cohen DJ. Postmortem analysis of subcortical monoamines and amino acids in Tourette syndrome. Advances In Neurology 1992, 58: 123-33. PMID: 1414615.
- Pathogenesis of Tourette syndrome. Clues from the clinical phenotype and natural history.Leckman JF, Pauls DL, Peterson BS, Riddle MA, Anderson GM, Cohen DJ. Pathogenesis of Tourette syndrome. Clues from the clinical phenotype and natural history. Advances In Neurology 1992, 58: 15-24. PMID: 1414618.
- Neuroendocrine and behavioral effects of naloxone in Tourette syndrome.Chappell PB, Leckman JF, Riddle MA, Anderson GM, Listwack SJ, Ort SI, Hardin MT, Scahill LD, Cohen DJ. Neuroendocrine and behavioral effects of naloxone in Tourette syndrome. Advances In Neurology 1992, 58: 253-62. PMID: 1414631.
- Tourette syndrome. Extending basic research to clinical care.Cohen DJ, Friedhoff AJ, Leckman JF, Chase TN. Tourette syndrome. Extending basic research to clinical care. Advances In Neurology 1992, 58: 341-62. PMID: 1414642.
- Detection of homeobox genes in development and evolution.Murtha MT, Leckman JF, Ruddle FH. Detection of homeobox genes in development and evolution. Proceedings Of The National Academy Of Sciences Of The United States Of America 1991, 88: 10711-10715. PMID: 1720547, PMCID: PMC53000, DOI: 10.1073/pnas.88.23.10711.
- Exacerbation of Gilles de la Tourette's syndrome associated with thermal stress: a family study.Lombroso PJ, Mack G, Scahill L, King RA, Leckman JF. Exacerbation of Gilles de la Tourette's syndrome associated with thermal stress: a family study. Neurology 1991, 41: 1984-7. PMID: 1745360, DOI: 10.1212/wnl.41.12.1984.
- Tourette's syndrome.Cohen DJ, Leckman JF. Tourette's syndrome. JAMA 1991, 265: 1738. PMID: 2002580, DOI: 10.1001/jama.265.13.1738.
- Clonidine Treatment of Gilles de la Tourette's SyndromeLeckman JF, Hardin MT, Riddle MA, Stevenson J, Ort SI, Cohen DJ. Clonidine Treatment of Gilles de la Tourette's Syndrome JAMA Psychiatry 1991, 48: 324-328. PMID: 2009034, DOI: 10.1001/archpsyc.1991.01810280040006.
- Basal ganglia research and Tourette's syndromeLeckman JF, Knorr AM, Rasmusson AM, Cohen DJ. Basal ganglia research and Tourette's syndrome Trends In Neurosciences 1991, 14: 94. PMID: 1709538, DOI: 10.1016/0166-2236(91)90066-4.
- Progress in the search for genetic linkage with Tourette syndrome: an exclusion map covering more than 50% of the autosomal genome.Pakstis AJ, Heutink P, Pauls DL, Kurlan R, van de Wetering BJ, Leckman JF, Sandkuyl LA, Kidd JR, Breedveld GJ, Castiglione CM. Progress in the search for genetic linkage with Tourette syndrome: an exclusion map covering more than 50% of the autosomal genome. American Journal Of Human Genetics 1991, 48: 281-94. PMID: 1990837, PMCID: PMC1683024.
- A family study of Gilles de la Tourette syndrome.Pauls DL, Raymond CL, Stevenson JM, Leckman JF. A family study of Gilles de la Tourette syndrome. American Journal Of Human Genetics 1991, 48: 154-63. PMID: 1985456, PMCID: PMC1682764.
- Beyond the serotonin hypothesis: a role for dopamine in some forms of obsessive compulsive disorder?Goodman WK, McDougle CJ, Price LH, Riddle MA, Pauls DL, Leckman JF. Beyond the serotonin hypothesis: a role for dopamine in some forms of obsessive compulsive disorder? The Journal Of Clinical Psychiatry 1990, 51 Suppl: 36-43; discussion 55-8. PMID: 2199433.
- Gilles de La Tourette's syndrome and some forms of obsessive-compulsive disorder may share a common genetic diathesis.Leckman JF, Chittenden EH. Gilles de La Tourette's syndrome and some forms of obsessive-compulsive disorder may share a common genetic diathesis. L'Encephale 1990, 16 Spec No: 321-3. PMID: 2209489.
- Possible exacerbation of tics by androgenic steroids.Leckman JF, Scahill L. Possible exacerbation of tics by androgenic steroids. The New England Journal Of Medicine 1990, 322: 1674. PMID: 2342531, DOI: 10.1056/nejm199006073222314.
- Thyroid function in fragile-X syndrome males.Bregman JD, Leckman JF, Ort SI. Thyroid function in fragile-X syndrome males. The Yale Journal Of Biology And Medicine 1990, 63: 293-9. PMID: 2125773, PMCID: PMC2589194.
- Plasma debrisoquin levels in the assessment of reduction of plasma homovanillic acid. The debrisoquin method.Riddle MA, Jatlow PI, Anderson GM, Cho SC, Hardin MT, Cohen DJ, Leckman JF. Plasma debrisoquin levels in the assessment of reduction of plasma homovanillic acid. The debrisoquin method. Neuropsychopharmacology 1989, 2: 123-9. PMID: 2742727, DOI: 10.1016/0893-133x(89)90015-8.
- Fluoxetine treatment of obsessions and compulsions in patients with Tourette's syndrome.Riddle MA, Leckman JF, Hardin MT, Anderson GM, Cohen DJ. Fluoxetine treatment of obsessions and compulsions in patients with Tourette's syndrome. The American Journal Of Psychiatry 1988, 145: 1173-4. PMID: 3046386, DOI: 10.1176/ajp.145.9.1173a.
- Tourette syndrome and neuropsychiatric disorders: is there a genetic relationship?Pauls DL, Cohen DJ, Kidd KK, Leckman JF. Tourette syndrome and neuropsychiatric disorders: is there a genetic relationship? American Journal Of Human Genetics 1988, 43: 206-17. PMID: 3165247, PMCID: PMC1715348.
- Elevated CSF dynorphin A [1–8] in Tourette's syndromeLeckman JF, Riddle MA, Berrettini WH, Anderson GM, Hardin M, Chappell P, Bissette G, Nemeroff CB, Goodman WK, Cohen DJ. Elevated CSF dynorphin A [1–8] in Tourette's syndrome Life Sciences 1988, 43: 2015-2023. PMID: 2463450, DOI: 10.1016/0024-3205(88)90575-9.
- The relationship between obsessive-compulsive disorder and Tourette's syndrome: a twin study.Walkup JT, Leckman JF, Price RA, Hardin M, Ort SI, Cohen DJ. The relationship between obsessive-compulsive disorder and Tourette's syndrome: a twin study. Psychopharmacology Bulletin 1988, 24: 375-9. PMID: 3153496.
- Strengths and weaknesses in the intellectual functioning of males with fragile X syndrome.Dykens EM, Hodapp RM, Leckman JF. Strengths and weaknesses in the intellectual functioning of males with fragile X syndrome. American Journal On Intellectual And Developmental Disabilities 1987, 92: 234-6. PMID: 3434594.
- Drug treatment of obsessive-compulsive disorder: a review of findings in the light of diagnostic and metric limitations.Towbin KE, Leckman JF, Cohen DJ. Drug treatment of obsessive-compulsive disorder: a review of findings in the light of diagnostic and metric limitations. Psychiatric Developments 1987, 5: 25-50. PMID: 2885832.
- Assessment of dopaminergic function in children and adults: long and brief debrisoquin administration combined with plasma homovanillic acid.Riddle MA, Leckman JF, Anderson GM, Hardin MT, Ort SI, Towbin KE, Shaywitz BA, Cohen DJ. Assessment of dopaminergic function in children and adults: long and brief debrisoquin administration combined with plasma homovanillic acid. Psychopharmacology Bulletin 1987, 23: 411-4. PMID: 3481088.
- Assessment or central dopaminergic function using plasma-free homovanillic acid after debrisoquin administrationRiddle MA, Leckman JF, Cohen DJ, Anderson M, Ort SI, Caruso KA, Shaywitz BA. Assessment or central dopaminergic function using plasma-free homovanillic acid after debrisoquin administration Journal Of Neural Transmission 1986, 67: 31-43. PMID: 3465864, DOI: 10.1007/bf01243357.
- Gilles de la Tourette's syndrome: tics and central nervous system stimulants in twins and nontwins.Price RA, Leckman JF, Pauls DL, Cohen DJ, Kidd KK. Gilles de la Tourette's syndrome: tics and central nervous system stimulants in twins and nontwins. Neurology 1986, 36: 232-7. PMID: 2868428, DOI: 10.1212/wnl.36.2.232.
- A possible genetic relationship exists between Tourette's syndrome and obsessive-compulsive disorder.Pauls DL, Leckman JF, Towbin KE, Zahner GE, Cohen DJ. A possible genetic relationship exists between Tourette's syndrome and obsessive-compulsive disorder. Psychopharmacology Bulletin 1986, 22: 730-3. PMID: 3467387.
- Computed tomographic brain scanning in four neuropsychiatric disorders of childhoodHarcherik DF, Cohen DJ, Ort S, Paul R, Shaywitz BA, Volkmar FR, Rothman SL, Leckman JF. Computed tomographic brain scanning in four neuropsychiatric disorders of childhood American Journal Of Psychiatry 1985, 142: 731-734. PMID: 3859227, DOI: 10.1176/ajp.142.6.731.
- Depressives with secondary alcoholism: psychiatric disorders in offspring.Merikangas KR, Weissman MM, Prusoff BA, Pauls DL, Leckman JF. Depressives with secondary alcoholism: psychiatric disorders in offspring. Journal Of Studies On Alcohol And Drugs 1985, 46: 199-204. PMID: 4010295, DOI: 10.15288/jsa.1985.46.199.
- Short- and long-term treatment of Tourette's syndrome with clonidine: a clinical perspective.Leckman JF, Detlor J, Harcherik DF, Ort S, Shaywitz BA, Cohen DJ. Short- and long-term treatment of Tourette's syndrome with clonidine: a clinical perspective. Neurology 1985, 35: 343-51. PMID: 3883235, DOI: 10.1212/wnl.35.3.343.
- Major depression and panic disorder: a family study perspective.Leckman JF, Weissman MM, Merikangas KR, Pauls DL, Prusoff BA, Kidd KK. Major depression and panic disorder: a family study perspective. Psychopharmacology Bulletin 1985, 21: 543-5. PMID: 4034871.
- Fragile X in a Survey of 75 Autistic MalesWatson MS, Leckman JF, Annex B, Breg WR, Boles D, Volkmar FR, Cohen DJ, Carter C. Fragile X in a Survey of 75 Autistic Males New England Journal Of Medicine 1984, 310: 1462. PMID: 6717529, DOI: 10.1056/nejm198405313102214.
- Tourette's syndrome: advances in treatment and research.Cohen DJ, Leckman JF. Tourette's syndrome: advances in treatment and research. Journal Of The American Academy Of Child Psychiatry 1984, 23: 123-5. PMID: 6585413, DOI: 10.1097/00004583-198403000-00001.
- On the study of children of parents with affective disorders.Solnit AJ, Leckman JF. On the study of children of parents with affective disorders. The American Journal Of Psychiatry 1984, 141: 241-2. PMID: 6691485, DOI: 10.1176/ajp.141.2.241.
- Psychiatric illness in relatives of probands with delusional depression.Prusoff BA, Weissman MM, Merikangas KR, Leckman JF, Harding PS. Psychiatric illness in relatives of probands with delusional depression. Psychopharmacology Bulletin 1984, 20: 358-61. PMID: 6473630.
- Anxiety disorders and depression: contradictions between family study data and DSM-III conventionsLeckman JF, Merikangas KR, Pauls DL, Prusoff BA, Weissman MM. Anxiety disorders and depression: contradictions between family study data and DSM-III conventions American Journal Of Psychiatry 1983, 140: 880-882. PMID: 6859304, DOI: 10.1176/ajp.140.7.880.
- Recent advances in Gilles de la Tourette syndrome: implications for clinical practice and future research.Leckman JF, Cohen DJ. Recent advances in Gilles de la Tourette syndrome: implications for clinical practice and future research. Psychiatric Developments 1983, 1: 301-16. PMID: 6324164.
- Developmental and pharmacological aspects of attention deficit disorder (ADD).Anderson GM, Shaywitz BA, Leckman JF, Hunt RD, Shaywitz SE, Cohen DJ. Developmental and pharmacological aspects of attention deficit disorder (ADD). Progress In Clinical And Biological Research 1983, 135: 207-23. PMID: 6364156.
- Clonidine in the treatment of Tourette syndrome: a review of data.Leckman JF, Cohen DJ, Detlor J, Young JG, Harcherik D, Shaywitz BA. Clonidine in the treatment of Tourette syndrome: a review of data. Advances In Neurology 1982, 35: 391-401. PMID: 6756089.
- Interaction of biological and psychological factors in the natural history of Tourette syndrome: a paradigm for childhood neuropsychiatric disorders.Cohen DJ, Detlor J, Shaywitz BA, Leckman JF. Interaction of biological and psychological factors in the natural history of Tourette syndrome: a paradigm for childhood neuropsychiatric disorders. Advances In Neurology 1982, 35: 31-40. PMID: 6959506.
- Induction of rapid mood cycling during L-dopa treatment in a bipolar patientKo GN, Leckman JF, Heninger GR. Induction of rapid mood cycling during L-dopa treatment in a bipolar patient American Journal Of Psychiatry 1981, 138: 1624-1625. PMID: 7304798, DOI: 10.1176/ajp.138.12.1624.
- Clonidine in Neonatal Narcotic-Abstinence SyndromeHoder EL, Leckman JF, Ehrenkranz R, Kleber H, Cohen DJ, Poulsen JA. Clonidine in Neonatal Narcotic-Abstinence Syndrome New England Journal Of Medicine 1981, 305: 1284. PMID: 7290147, DOI: 10.1056/nejm198111193052114.
- Relationship between estimated premorbid adjustment and CSF homovanillic acid and 5-hydroxyindoleacetic acid levelsLeckman JF, Bowers MB, Sturges JS. Relationship between estimated premorbid adjustment and CSF homovanillic acid and 5-hydroxyindoleacetic acid levels American Journal Of Psychiatry 1981, 138: 472-477. PMID: 6163366, DOI: 10.1176/ajp.138.4.472.
- Intravenous chlorimipramine affects REM cycle in patients with excessive daytime sleepiness and control subjects.Leckman JF, Gillin JC, Sitaram N, Duncan W, Wyatt RJ. Intravenous chlorimipramine affects REM cycle in patients with excessive daytime sleepiness and control subjects. Communications In Psychopharmacology 1980, 4: 35-40. PMID: 7398240.
- Platelet monoamine oxidase (MAO) activity and genetic vulnerability to bipolar (BP) affective illness.Gershon ES, Targum SD, Leckman JF. Platelet monoamine oxidase (MAO) activity and genetic vulnerability to bipolar (BP) affective illness. Psychopharmacology Bulletin 1979, 15: 27-30. PMID: 419242.
- Pentylenetetrazol in the treatment of geriatric patients with disturbed memory function.Leckman J, Ananth JV, Ban TA, Lehmann HE. Pentylenetetrazol in the treatment of geriatric patients with disturbed memory function. The Journal Of Clinical Pharmacology And New Drugs 1971, 11: 301-3. PMID: 4932747.
Clinical Trials
Conditions | Study Title |
---|---|
Child Development & Autism; Children's Health; Mental Health & Behavioral Research | Anger Control Training for Youth With Tourette Syndrome |
Diseases of the Nervous System; Mental Health & Behavioral Research | Neurofeedback for Obsessive-Compulsive Disorder |