Charles Wira, MD

• Adam de Havenon
• Adam Jasne
• Adithya Sivaraju
• Ajay Malhotra
• Akhil Khosla
• Andrew Ulrich
• Ani Aydin
• Basmah Safdar
• Charles Matouk
• Christopher L Moore
• Emily J. Gilmore
• Guido J. Falcone
• Howard Forman
• James Bonz
• James Daley
• James Dziura
• Jeremy J. Moeller
• Joseph Schindler
• Juan Carlos Perez Lozada
• Judith Lichtman
• Justin Belsky
• Kevin Gobeske
• Kevin Sheth
• Lauren Hachmann Sansing
• Lawrence Hirsch
• Lee Schwamm
• Nils Petersen
• Rachel Beekman
• Rachel Liu
• Reinier Van Tonder
• Ryan Coughlin
• Ryan JJ Buckley
• Ryan M Hebert
• Sam Payabvash
• Serena Spudich
• Steven Schiff
• Vivek Parwani

Emergency Medicine; Heart Arrest; Sepsis; Stroke

• Identification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imagingde Havenon A, Parasuram N, Crawford A, Mazurek M, Chavva I, Yadlapalli V, Iglesias J, Rosen M, Falcone G, Payabvash S, Sze G, Sharma R, Schiff S, Safdar B, Wira C, Kimberly W, Sheth K. Identification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imaging. Journal Of The American Heart Association 2023, 12: e029242. PMID: 37218590, PMCID: PMC10381997, DOI: 10.1161/jaha.122.029242.
• Validation of the rCAST score and comparison to the PCAC and FOUR scores for prognostication after out-of-hospital cardiac arrestKim N, Kitlen E, Garcia G, Khosla A, Miller P, Johnson J, Wira C, Greer D, Gilmore E, Beekman R. Validation of the rCAST score and comparison to the PCAC and FOUR scores for prognostication after out-of-hospital cardiac arrest. Resuscitation 2023, 188: 109832. PMID: 37178901, DOI: 10.1016/j.resuscitation.2023.109832.
• Diagnosis, Workup, Risk Reduction of Transient Ischemic Attack in the Emergency Department Setting: A Scientific Statement From the American Heart AssociationAmin H, Madsen T, Bravata D, Wira C, Johnston S, Ashcraft S, Burrus T, Panagos P, Wintermark M, Esenwa C, Disease O. Diagnosis, Workup, Risk Reduction of Transient Ischemic Attack in the Emergency Department Setting: A Scientific Statement From the American Heart Association. Stroke 2023, 54: e109-e121. PMID: 36655570, DOI: 10.1161/str.0000000000000418.
• Abstract 159: Time-course Of Left Ventricular Systolic Dysfunction Recovery After Cardiac ArrestBeekman R, Kim N, Faridi K, Aneni E, Chang T, Arakaki A, Kitlen E, Miller E, Khosla A, Wira C, Greer D, gilmore E. Abstract 159: Time-course Of Left Ventricular Systolic Dysfunction Recovery After Cardiac Arrest. Circulation 2022, 146: a159-a159. DOI: 10.1161/circ.146.suppl_1.159.
• Abstract 156: Clinical Significance Of Left Ventricular Systolic Dysfunction After Cardiac ArrestBeekman R, Kim N, Faridi K, Aneni E, Chang T, Arakaki A, Kitlen E, Miller E, Khosla A, Wira C, Greer D, gilmore E. Abstract 156: Clinical Significance Of Left Ventricular Systolic Dysfunction After Cardiac Arrest. Circulation 2022, 146: a156-a156. DOI: 10.1161/circ.146.suppl_1.156.
• Abstract WP111: Deployment Of Portable, Bedside, Low-field Magnetic Resonance Imaging In The Emergency Department To Evaluate Patients With Acute StrokeChavva I, Mazurek M, Yuen M, Prabhat A, Crawford A, Cahn B, Schindler J, Sansing L, Matouk C, Hebert R, de Havenon A, Sharma R, Payabvash S, Sze G, Aydin A, Parwani V, Ulrich A, Brown K, Sheth K, Wira C. Abstract WP111: Deployment Of Portable, Bedside, Low-field Magnetic Resonance Imaging In The Emergency Department To Evaluate Patients With Acute Stroke. Stroke 2022, 53: awp111-awp111. DOI: 10.1161/str.53.suppl_1.wp111.
• Abstract WMP59: Trends And Predictors Of Delay In Hospital Presentation After Symptom Onset Among Ischemic Stroke Patients: A Single-center StudyOkumu R, Baker A, Wira C, Schindler J, Sansing L, Jasne A, Amin H, Narula R, Forman R, Sharma R. Abstract WMP59: Trends And Predictors Of Delay In Hospital Presentation After Symptom Onset Among Ischemic Stroke Patients: A Single-center Study. Stroke 2022, 53: awmp59-awmp59. DOI: 10.1161/str.53.suppl_1.wmp59.
• Drip-and-ship versus mothership for endovascular treatment of acute stroke: A comparative effectiveness analysisWu X, Wira C, Matouk C, Forman H, Gandhi D, Sanelli P, Schindler J, Malhotra A. Drip-and-ship versus mothership for endovascular treatment of acute stroke: A comparative effectiveness analysis. International Journal Of Stroke 2021, 17: 315-322. PMID: 33759645, DOI: 10.1177/17474930211008701.
• Abstract 33: Qualitative Description of Ischemic Stroke Appearance on Low-Field, Point-Of-Care Magnetic Resonance ImagingYuen M, Mazurek M, Cahn B, Prabhat A, By S, Hu H, Welch E, Sacolick L, O’Halloran R, Ward A, Timario N, Falcone G, Gilmore E, Hwang D, Kim J, Kaddouh F, Sharma R, Amin H, Schindler J, Matouk C, Hebert R, Wira C, Sze G, Rosen M, Kimberly W, Sheth K. Abstract 33: Qualitative Description of Ischemic Stroke Appearance on Low-Field, Point-Of-Care Magnetic Resonance Imaging. Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.33.
• Abstract MP36: Blood Pressure Reductions in the Hyperacute Phase of Large Vessel Occlusion Ischemic Stroke Are Associated With Infarct Progression and Poor Functional OutcomePeshwe K, Nguyen C, Kodali S, Kobsa J, Prasad A, Soto A, Wira C, Matouk C, Sheth K, Petersen N. Abstract MP36: Blood Pressure Reductions in the Hyperacute Phase of Large Vessel Occlusion Ischemic Stroke Are Associated With Infarct Progression and Poor Functional Outcome. Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.mp36.
• Research Protocol and Case Report of Emergency Department Endovascular Aortic Occlusion (REBOA) in Non-traumatic Cardiac ArrestDaley J, Cannon K, Buckley R, Aydin A, Latich I, Perez Lozada J, Bonz J, Joseph D, Coughlin R, Belsky J, Sather J, Wira C, Liu R, Johnson A, Moore C. Research Protocol and Case Report of Emergency Department Endovascular Aortic Occlusion (REBOA) in Non-traumatic Cardiac Arrest. Journal Of Endovascular Resuscitation And Trauma Management 2020, 4 DOI: 10.26676/jevtm.v40i(2).140.
• A Research Protocol and Case Report of Emergency Department Endovascular Aortic Occlusion (REBOA) in Non-traumatic Cardiac ArrestDaley J, Cannon K, Buckley R, Aydin A, Latich I, Lozada J, Bonz J, Joseph D, Coughlin R, Belsky J, Van Tonder R, Sather J, Wira C, Liu R, Johnson A, Moore C. A Research Protocol and Case Report of Emergency Department Endovascular Aortic Occlusion (REBOA) in Non-traumatic Cardiac Arrest. Journal Of Endovascular Resuscitation And Trauma Management 2020, 4: 88-93. DOI: 10.26676/jevtm.v4i2.140.
• Crisis Resource Management and High-Performing Teams in Hyperacute Stroke CareRajendram P, Notario L, Reid C, Wira CR, Suarez JI, Weingart SD, Khosravani H. Crisis Resource Management and High-Performing Teams in Hyperacute Stroke Care. Neurocritical Care 2020, 33: 338-346. PMID: 32794144, PMCID: PMC7426067, DOI: 10.1007/s12028-020-01057-4.
• Stroke Code Presentations, Interventions, and Outcomes Before and During the COVID-19 PandemicJasne AS, Chojecka P, Maran I, Mageid R, Eldokmak M, Zhang Q, Nystrom K, Vlieks K, Askenase M, Petersen N, Falcone GJ, Wira CR, Lleva P, Zeevi N, Narula R, Amin H, Navaratnam D, Loomis C, Hwang DY, Schindler J, Hebert R, Matouk C, Krumholz HM, Spudich S, Sheth KN, Sansing LH, Sharma R. Stroke Code Presentations, Interventions, and Outcomes Before and During the COVID-19 Pandemic. Stroke 2020, 51: 2664-2673. PMID: 32755347, PMCID: PMC7446978, DOI: 10.1161/str.0000000000000347.
• Pandemic Guidance for Stroke Centers Aiding COVID-19 Treatment TeamsWira CR, Goyal M, Southerland AM, Sheth KN, McNair ND, Khosravani H, Leonard A, Panagos P, Council O. Pandemic Guidance for Stroke Centers Aiding COVID-19 Treatment Teams. Stroke 2020, 51: 10.1161/strokeaha.120.030749. PMID: 32716826, PMCID: PMC7326321, DOI: 10.1161/strokeaha.120.030749.
• Prehospital Triage of Acute Stroke Patients During the COVID-19 PandemicGoyal M, Ospel JM, Southerland AM, Wira C, Amin-Hanjani S, Fraser JF, Panagos P, Committees O. Prehospital Triage of Acute Stroke Patients During the COVID-19 Pandemic. Stroke 2020, 51: 2263-2267. PMID: 32401680, DOI: 10.1161/strokeaha.120.030340.
• Abstract 57: Deployment of Portable, Bedside, Low-Field Magnetic Resonance Imaging for Evaluation of Stroke PatientsCahn B, Shah J, Dyvorne H, O'Halloran R, Poole M, Yuen M, Mazurek M, Ward A, Payabvash S, Beekman R, Brown S, Falcone G, Gobeske K, Petersen N, Jasne A, Sharma R, Schindler J, Sansing L, Gilmore E, Wira C, Matouk C, Sze G, Rosen M, Kimberly W, Sheth K. Abstract 57: Deployment of Portable, Bedside, Low-Field Magnetic Resonance Imaging for Evaluation of Stroke Patients. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.57.
• Abstract WP374: High Frequency Blood Pressure Monitoring in the Acute Phase of Large Vessel Occlusion Ischemic StrokePeshwe K, Nguyen C, Kimmel A, Kodali S, Silverman A, Strander S, Wang A, Wira C, Sansing L, Matouk C, Sheth K, Petersen N. Abstract WP374: High Frequency Blood Pressure Monitoring in the Acute Phase of Large Vessel Occlusion Ischemic Stroke. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp374.
• Abstract WP354: The Rural Health Care Penalty: Urban-rural Disparities in Stroke Center PerformanceGropen T, Beasley M, Wira C, Egan A, Madsen T, Magdon-Ismail Z. Abstract WP354: The Rural Health Care Penalty: Urban-rural Disparities in Stroke Center Performance. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp354.
• CT Angiography for Triage of Patients with Acute Minor Stroke: A Cost-effectiveness Analysis.Wu X, Hughes DR, Gandhi D, Matouk CC, Sheth K, Schindler J, Wira C, Wintermark M, Sanelli P, Malhotra A. CT Angiography for Triage of Patients with Acute Minor Stroke: A Cost-effectiveness Analysis. Radiology 2020, 294: 580-588. PMID: 31934828, DOI: 10.1148/radiol.2019191238.
• Mobile Stroke Units—the Changing Face of Emergency Medicine Stroke ManagementWira C, Aydin A. Mobile Stroke Units—the Changing Face of Emergency Medicine Stroke Management. Current Emergency And Hospital Medicine Reports 2020, 8: 9-15. DOI: 10.1007/s40138-020-00207-4.
• Stroke Center Certification and Performance: A Longitudinal Analysis of the Northeast Cerebrovascular Consortium Region.Wira CR, Melluzzo S, Beasley TM, Magdon-Ismail Z, Day D, Madsen TE, McCullough LD, Stein J, Schwamm LH, Gropen T. Stroke Center Certification and Performance: A Longitudinal Analysis of the Northeast Cerebrovascular Consortium Region. The Yale Journal Of Biology And Medicine 2019, 92: 587-596. PMID: 31866774, PMCID: PMC6913814.
• The Future of Minor Stroke and Transient Ischemic Attack: The RAVEN Approach Is Promising but Not Ready for Prime TimeMadsen TE, Wira CR. The Future of Minor Stroke and Transient Ischemic Attack: The RAVEN Approach Is Promising but Not Ready for Prime Time. Annals Of Emergency Medicine 2019, 74: 572-574. PMID: 31543123, DOI: 10.1016/j.annemergmed.2019.08.458.
• Guiding Cardiopulmonary Resuscitation with Focused Echocardiography: A Report of Five CasesLiu R, Bogucki S, Marcolini EG, Yu CY, Wira CR, Kalam S, Daley J, Moore CL, Cone D. Guiding Cardiopulmonary Resuscitation with Focused Echocardiography: A Report of Five Cases. Prehospital Emergency Care 2019, 24: 297-302. PMID: 31150302, DOI: 10.1080/10903127.2019.1626955.
• Is There a Neurologist in the House? A Summary of the Current State of Neurovascular Rotations for Emergency Medicine ResidentsWira CR, Madsen TE, Chang BP, Nomura JT, Marcolini E, Gentile NT, Schreyer KE, Merck LH, Siket M, Greenberg K, Zammit CG, Jauch EC, Bellolio M, Group F. Is There a Neurologist in the House? A Summary of the Current State of Neurovascular Rotations for Emergency Medicine Residents. AEM Education And Training 2018, 2: s56-s67. PMID: 30607380, PMCID: PMC6304277, DOI: 10.1002/aet2.10200.
• A review of micronutrients in sepsis: the role of thiamine, l-carnitine, vitamin C, selenium and vitamin DBelsky JB, Wira CR, Jacob V, Sather JE, Lee PJ. A review of micronutrients in sepsis: the role of thiamine, l-carnitine, vitamin C, selenium and vitamin D. Nutrition Research Reviews 2018, 31: 281-290. PMID: 29984680, DOI: 10.1017/s0954422418000124.
• Sex as a Biological Variable in Emergency Medicine Research and Clinical Practice: A Brief Narrative ReviewMcGregor AJ, Beauchamp GA, Wira CR, Perman SM, Safdar B. Sex as a Biological Variable in Emergency Medicine Research and Clinical Practice: A Brief Narrative Review. Western Journal Of Emergency Medicine 2017, 18: 1079-1090. PMID: 29085541, PMCID: PMC5654878, DOI: 10.5811/westjem.2017.8.34997.
• Neurology Concepts: Young Women and Ischemic Stroke—Evaluation and Management in the Emergency DepartmentChang BP, Wira C, Miller J, Akhter M, Barth BE, Willey J, Nentwich L, Madsen T. Neurology Concepts: Young Women and Ischemic Stroke—Evaluation and Management in the Emergency Department. Academic Emergency Medicine 2017, 25: 54-64. PMID: 28646558, PMCID: PMC6415947, DOI: 10.1111/acem.13243.
• Infections of the Central Nervous SystemFelton O, Wira C. Infections of the Central Nervous System. 2017, 251-270. DOI: 10.1007/978-3-319-64523-0_13.
• Abstract 116: Minorities, Women, and Stroke Belters Left Behind in t-PA Use Despite Quality Improvement EffortsMadsen T, Melluzzo S, Wira C, Magdon-Ismail Z, Day D, Gropen T. Abstract 116: Minorities, Women, and Stroke Belters Left Behind in t-PA Use Despite Quality Improvement Efforts. Stroke 2017, 48 DOI: 10.1161/str.48.suppl_1.116.
• Evaluation of a novel 5-group classification system of sepsis by vasopressor use and initial serum lactate in the emergency departmentSwenson KE, Dziura JD, Aydin A, Reynolds J, Wira CR. Evaluation of a novel 5-group classification system of sepsis by vasopressor use and initial serum lactate in the emergency department. Internal And Emergency Medicine 2017, 13: 257-268. PMID: 28132131, DOI: 10.1007/s11739-017-1607-y.
• Volume of Plasma Expansion and Functional Outcomes in StrokeMiller JB, Lewandowski C, Wira CR, Taylor A, Burmeister C, Welch R. Volume of Plasma Expansion and Functional Outcomes in Stroke. Neurocritical Care 2016, 26: 191-195. PMID: 27629275, DOI: 10.1007/s12028-016-0316-0.
• The Advanced Reperfusion Era: Implications for Emergency Systems of Ischemic Stroke CareMiller JB, Merck LH, Wira CR, Meurer WJ, Schrock JW, Nomura JT, Siket MS, Madsen TE, Wright DW, Panagos PD, Lewandowski C. The Advanced Reperfusion Era: Implications for Emergency Systems of Ischemic Stroke Care. Annals Of Emergency Medicine 2016, 69: 192-201. PMID: 27600649, DOI: 10.1016/j.annemergmed.2016.06.042.
• Composition of the Sepsis Definitions Task ForceWira CR, Swenson KE. Composition of the Sepsis Definitions Task Force. JAMA 2016, 316: 460-460. PMID: 27458964, DOI: 10.1001/jama.2016.6371.
• When to Stop CPR and When to Perform Rhythm AnalysisGiberson B, Uber A, Gaieski D, Miller JB, Wira C, Berg K, Giberson T, Cocchi MN, Abella B, Donnino MW. When to Stop CPR and When to Perform Rhythm Analysis. Journal Of Intensive Care Medicine 2016, 31: 537-543. PMID: 25542192, DOI: 10.1177/0885066614561589.
• Validation of TURN, a simple predictor of symptomatic intracerebral hemorrhage after IV thrombolysisAsuzu D, Nystrӧm K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. Validation of TURN, a simple predictor of symptomatic intracerebral hemorrhage after IV thrombolysis. Clinical Neurology And Neurosurgery 2016, 146: 71-75. PMID: 27152469, DOI: 10.1016/j.clineuro.2016.04.017.
• Risk rtPA: An iOS mobile application based on TURN for predicting 90-day outcome after IV thrombolysisAsuzu D, Nystrӧm K, Schindler J, Wira C, Greer D, Halliday J, Sheth KN. Risk rtPA: An iOS mobile application based on TURN for predicting 90-day outcome after IV thrombolysis. Clinical Neurology And Neurosurgery 2016, 142: 148-152. PMID: 26875069, DOI: 10.1016/j.clineuro.2016.01.030.
• Missed Ischemic Stroke Diagnosis in the Emergency Department by Emergency Medicine and Neurology ServicesArch AE, Weisman DC, Coca S, Nystrom KV, Wira CR, Schindler JL. Missed Ischemic Stroke Diagnosis in the Emergency Department by Emergency Medicine and Neurology Services. Stroke 2016, 47: 668-673. PMID: 26846858, DOI: 10.1161/strokeaha.115.010613.
• Abstract TP240: Missed Ischemic Stroke Diagnosis in the Emergency Department at an Academic Center and Community HospitalArch A, Weisman D, Coca S, Nystrom K, Wira C, Schindler J. Abstract TP240: Missed Ischemic Stroke Diagnosis in the Emergency Department at an Academic Center and Community Hospital. Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.tp240.
• Lactate Clearance Predicts Survival Among Patients in the Emergency Department with Severe SepsisBhat SR, Swenson KE, Francis MW, Wira CR. Lactate Clearance Predicts Survival Among Patients in the Emergency Department with Severe Sepsis. Western Journal Of Emergency Medicine 2015, 16: 1118-1126. PMID: 26759665, PMCID: PMC4703153, DOI: 10.5811/westjem.2015.10.27577.
• On- versus Off-Hour Patient Cohorts at a Primary Stroke Center: Onset-to-Treatment Duration and Clinical Outcomes after IV ThrombolysisAsuzu D, Nystrӧm K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. On- versus Off-Hour Patient Cohorts at a Primary Stroke Center: Onset-to-Treatment Duration and Clinical Outcomes after IV Thrombolysis. Journal Of Stroke And Cerebrovascular Diseases 2015, 25: 447-451. PMID: 26654664, DOI: 10.1016/j.jstrokecerebrovasdis.2015.10.017.
• TURN Score Predicts 24-Hour Cerebral Edema After IV ThrombolysisAsuzu D, Nyström K, Sreekrishnan A, Schindler J, Wira C, Greer D, Halliday J, Kimberly WT, Sheth KN. TURN Score Predicts 24-Hour Cerebral Edema After IV Thrombolysis. Neurocritical Care 2015, 24: 381-388. PMID: 26341364, DOI: 10.1007/s12028-015-0198-6.
• The Emergency Medicine Debate on tPA for Stroke: What Is Best for Our Patients? Efficacy in the First Three HoursMiller JB, Heitsch L, Siket MS, Schrock JW, Wira CR, Lewandowski C, Madsen TE, Merck LH, Wright DW, Group. F. The Emergency Medicine Debate on tPA for Stroke: What Is Best for Our Patients? Efficacy in the First Three Hours. Academic Emergency Medicine 2015, 22: 852-855. PMID: 26113369, DOI: 10.1111/acem.12712.
• Cause of an Elevated Lactate LevelSwenson KE, Wira CR. Cause of an Elevated Lactate Level. JAMA 2015, 313: 2381-2381. PMID: 26080348, DOI: 10.1001/jama.2015.5043.
• TURN Score Predicts 90-day Outcome in Acute Ischemic Stroke Patients After IV ThrombolysisAsuzu D, Nyström K, Schindler J, Wira C, Greer D, Halliday J, Sheth KN. TURN Score Predicts 90-day Outcome in Acute Ischemic Stroke Patients After IV Thrombolysis. Neurocritical Care 2015, 23: 172-178. PMID: 26032809, DOI: 10.1007/s12028-015-0154-5.
• Prognostication of post-cardiac arrest coma: early clinical and electroencephalographic predictors of outcomeSivaraju A, Gilmore EJ, Wira CR, Stevens A, Rampal N, Moeller JJ, Greer DM, Hirsch LJ, Gaspard N. Prognostication of post-cardiac arrest coma: early clinical and electroencephalographic predictors of outcome. Intensive Care Medicine 2015, 41: 1264-1272. PMID: 25940963, DOI: 10.1007/s00134-015-3834-x.
• Abstract 306: Regional Differences in Stroke Center Designation and Get with The Guidelines (GWTG-S) Participation and Performance: Results From The NorthEast Cerebrovascular Consortium (NECC)Gropen T, Wira C, Melluzzo S, Magdon-Ismail Z, Day D, Madsen T, Schwamm L. Abstract 306: Regional Differences in Stroke Center Designation and Get with The Guidelines (GWTG-S) Participation and Performance: Results From The NorthEast Cerebrovascular Consortium (NECC). Circulation Cardiovascular Quality And Outcomes 2015, 8 DOI: 10.1161/circoutcomes.8.suppl_2.306.
• TURN: A Simple Predictor of Symptomatic Intracerebral Hemorrhage After IV ThrombolysisAsuzu D, Nyström K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. TURN: A Simple Predictor of Symptomatic Intracerebral Hemorrhage After IV Thrombolysis. Neurocritical Care 2015, 23: 166-171. PMID: 25869481, DOI: 10.1007/s12028-015-0131-z.
• Cohort-Based Identification of Predictors of Symptomatic Intracerebral Hemorrhage After IV ThrombolysisAsuzu D, Nyström K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. Cohort-Based Identification of Predictors of Symptomatic Intracerebral Hemorrhage After IV Thrombolysis. Neurocritical Care 2015, 23: 394-400. PMID: 25691004, DOI: 10.1007/s12028-015-0121-1.
• Abstract W MP76: Diagnostic Accuracy and Characteristics of Missed Ischemic Strokes in the Emergency DepartmentArch A, Nystrom K, Coca S, Wira C, Schindler J. Abstract W MP76: Diagnostic Accuracy and Characteristics of Missed Ischemic Strokes in the Emergency Department. Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.wmp76.
• Goal-Directed Therapy for Sepsis: Has the Beast Been Slain or Do Questions Remain?Wira CR, Swenson K. Goal-Directed Therapy for Sepsis: Has the Beast Been Slain or Do Questions Remain? Connecticut Medicine 2015, 79: 97-9. PMID: 26244208.
• Modest Association between the Discharge Modified Rankin Scale Score and Symptomatic Intracerebral Hemorrhage after Intravenous ThrombolysisAsuzu D, Nystrom K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. Modest Association between the Discharge Modified Rankin Scale Score and Symptomatic Intracerebral Hemorrhage after Intravenous Thrombolysis. Journal Of Stroke And Cerebrovascular Diseases 2014, 24: 548-553. PMID: 25540072, DOI: 10.1016/j.jstrokecerebrovasdis.2014.09.034.
• Gender Differences in Neurologic Emergencies Part I: A Consensus Summary and Research Agenda on Cerebrovascular DiseaseMadsen TE, Seigel TA, Mackenzie RS, Marcolini EG, Wira CR, Healy ME, Wright DW, Gentile NT. Gender Differences in Neurologic Emergencies Part I: A Consensus Summary and Research Agenda on Cerebrovascular Disease. Academic Emergency Medicine 2014, 21: 1403-1413. PMID: 25422086, DOI: 10.1111/acem.12528.
• Early Identification and Management of Patients with Severe Sepsis and Septic Shock in the Emergency DepartmentKeegan J, Wira CR. Early Identification and Management of Patients with Severe Sepsis and Septic Shock in the Emergency Department. Emergency Medicine Clinics Of North America 2014, 32: 759-776. PMID: 25441033, DOI: 10.1016/j.emc.2014.07.002.
• Comparison of 8 Scores for predicting Symptomatic Intracerebral Hemorrhage after IV ThrombolysisAsuzu D, Nystrom K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. Comparison of 8 Scores for predicting Symptomatic Intracerebral Hemorrhage after IV Thrombolysis. Neurocritical Care 2014, 22: 229-233. PMID: 25168743, DOI: 10.1007/s12028-014-0060-2.
• Abstract W P266: The Discharge Modified Rankin Score Correlates with Established Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated with ThrombolysisAsuzu D, Nystrom K, Sheth K, Halliday J, Wira C, Greer D, Pritchard D, Schindler J. Abstract W P266: The Discharge Modified Rankin Score Correlates with Established Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated with Thrombolysis. Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.wp266.
• Abstract W P265: Improved Symptomatic ICH Rates for Ischemic Stroke Patients Receiving IV rtPANystrom K, Asuzu D, Sheth K, Chi N, Halliday J, Wira C, Greer D, Schindler J. Abstract W P265: Improved Symptomatic ICH Rates for Ischemic Stroke Patients Receiving IV rtPA. Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.wp265.
• Abstract W P64: DRAGON Score Outperforms 7 Other Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated With IV r-tPAAsuzu D, Nystrom K, Chi N, Greer D, Halliday J, Wira C, Sschindler J, Sheth K. Abstract W P64: DRAGON Score Outperforms 7 Other Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated With IV r-tPA. Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.wp64.
• Meta-analysis of Protocolized Goal-Directed Hemodynamic Optimization for the Management of Severe Sepsis and Septic Shock in the Emergency DepartmentWira CR, Dodge K, Sather J, Dziura J. Meta-analysis of Protocolized Goal-Directed Hemodynamic Optimization for the Management of Severe Sepsis and Septic Shock in the Emergency Department. Western Journal Of Emergency Medicine 2014, 15: 51-59. PMID: 24696750, PMCID: PMC3952890, DOI: 10.5811/westjem.2013.7.6828.
• The Shock Index as a Predictor of Vasopressor Use in Emergency Department Patients with Severe SepsisWira CR, Francis MW, Bhat S, Ehrman R, Conner D, Siegel M. The Shock Index as a Predictor of Vasopressor Use in Emergency Department Patients with Severe Sepsis. Western Journal Of Emergency Medicine 2014, 15: 60-66. PMID: 24696751, PMCID: PMC3952891, DOI: 10.5811/westjem.2013.7.18472.
• Abstract WP381: Hospital Participation and Performance in Stroke Systems of Care: Results from The NorthEast Cerebrovascular Consortium (NECC) RegionWira C, Magdon-Ismail Z, Melluzzo S, Day D, McCullough L, Stein J, Schwamm L, Gropen T. Abstract WP381: Hospital Participation and Performance in Stroke Systems of Care: Results from The NorthEast Cerebrovascular Consortium (NECC) Region. Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.awp381.
• Missed Opportunities for Recognition of Ischemic Stroke in the Emergency DepartmentLever NM, Nyström KV, Schindler JL, Halliday J, Wira C, Funk M. Missed Opportunities for Recognition of Ischemic Stroke in the Emergency Department. Journal Of Emergency Nursing 2012, 39: 434-439. PMID: 22633790, DOI: 10.1016/j.jen.2012.02.011.
• Abstract 176: Regional Stroke Networks May Fill Gaps for Community and Quality ImprovementJanjua N, Melluzzo S, Wira C, Magdon-Ismail Z, Day D, McCullough L, Stein J, Lichtman J, Gropen T. Abstract 176: Regional Stroke Networks May Fill Gaps for Community and Quality Improvement. Circulation Cardiovascular Quality And Outcomes 2012, 5 DOI: 10.1161/circoutcomes.5.suppl_1.a176.
• Cardiac Complications in Acute Ischemic StrokeWira CR, Rivers E, Martinez-Capolino C, Silver B, Iyer G, Sherwin R, Lewandowski C. Cardiac Complications in Acute Ischemic Stroke. Western Journal Of Emergency Medicine 2011, 12: 414-420. PMID: 22224130, PMCID: PMC3236132, DOI: 10.5811/westjem.2011.2.1765.
• Epidemiology and Outcomes of Fever Burden Among Patients With Acute Ischemic StrokePhipps MS, Desai RA, Wira C, Bravata DM. Epidemiology and Outcomes of Fever Burden Among Patients With Acute Ischemic Stroke. Stroke 2011, 42: 3357-3362. PMID: 21980196, DOI: 10.1161/strokeaha.111.621425.
• The impact of cardiac contractility on cerebral blood flow in ischemia.Wira CR, Rivers E, Silver B, Lewandowski C. The impact of cardiac contractility on cerebral blood flow in ischemia. Western Journal Of Emergency Medicine 2011, 12: 227-32. PMID: 21691533, PMCID: PMC3099614.
• Etomidate use in severe sepsis and septic shock patients does not contribute to mortalityEhrman R, Wira C, Lomax A, Hayward A, Marcelin J, Ellis T, Przyklenk K, Volturo G, Mullen M. Etomidate use in severe sepsis and septic shock patients does not contribute to mortality. Internal And Emergency Medicine 2011, 6: 253-257. PMID: 21394520, DOI: 10.1007/s11739-011-0553-3.
• Cardiac Complications in Acute Ischemic StrokeWira C, Rivers E, Martinez-Capolino C, Silver B, Iyer G, Sherwin R, Lewandowski C. Cardiac Complications in Acute Ischemic Stroke. Western Journal Of Emergency Medicine 2011, 12: 414-420. DOI: 10.5811/westjem.2011.2.1785.
• 362: Etomidate Use In Sepsis Does Not Increase MortalityEhrman R, Wira C, Hayward A, Lomax A, Mullen M. 362: Etomidate Use In Sepsis Does Not Increase Mortality. Annals Of Emergency Medicine 2010, 56: s117. DOI: 10.1016/j.annemergmed.2010.06.419.
• Surviving sepsis in low-income and middle-income countries: new directions for care and researchBecker JU, Theodosis C, Jacob ST, Wira CR, Groce NE. Surviving sepsis in low-income and middle-income countries: new directions for care and research. The Lancet Infectious Diseases 2009, 9: 577-582. PMID: 19695494, DOI: 10.1016/s1473-3099(09)70135-5.
• Clinical risk stratification for gastrointestinal hemorrhage: still no consensusWira C, Sather J. Clinical risk stratification for gastrointestinal hemorrhage: still no consensus. Critical Care 2008, 12: 154. PMID: 18533048, PMCID: PMC2481453, DOI: 10.1186/cc6900.
• Anti-arrhythmic and vasopressor medications for the treatment of ventricular fibrillation in severe hypothermia: A systematic review of the literatureWira CR, Becker JU, Martin G, Donnino MW. Anti-arrhythmic and vasopressor medications for the treatment of ventricular fibrillation in severe hypothermia: A systematic review of the literature. Resuscitation 2008, 78: 21-29. PMID: 18406039, DOI: 10.1016/j.resuscitation.2008.01.025.
• Effective lactate clearance is associated with improved outcome in post-cardiac arrest patientsDonnino MW, Miller J, Goyal N, Loomba M, Sankey SS, Dolcourt B, Sherwin R, Otero R, Wira C. Effective lactate clearance is associated with improved outcome in post-cardiac arrest patients. Resuscitation 2007, 75: 229-234. PMID: 17583412, DOI: 10.1016/j.resuscitation.2007.03.021.
• 65 Correlation of Ejection Fraction with Transcranial Doppler Flow Rates in Acute Stroke PatientsWira C, Lewandowski C, Silver B, Martinez-Capolino C, Rivers E. 65 Correlation of Ejection Fraction with Transcranial Doppler Flow Rates in Acute Stroke Patients. Annals Of Emergency Medicine 2006, 48: 20. DOI: 10.1016/j.annemergmed.2006.07.513.
• 66 Myocardial and Hemodynamic Abnormalities in Patients with Acute Strokes and Transient Ischemic AttacksWira C, Lewandowski C, Martinez-Capolino C, Iyer G, Sherwin R, Kummer J, Rivers E. 66 Myocardial and Hemodynamic Abnormalities in Patients with Acute Strokes and Transient Ischemic Attacks. Annals Of Emergency Medicine 2006, 48: 20-21. DOI: 10.1016/j.annemergmed.2006.07.514.
• Application of normothermic cardiac arrest algorithms to hypothermic cardiac arrest in a canine modelWira C, Martin G, Stoner J, Margolis K, Donnino M. Application of normothermic cardiac arrest algorithms to hypothermic cardiac arrest in a canine model. Resuscitation 2006, 69: 509-516. PMID: 16597482, DOI: 10.1016/j.resuscitation.2005.10.028.
• The Chain of Survival: Is It Time for a Fifth Link?Garcia A, Donnino M, Rivers E, Shirazi E, Wira C, Goyal N, Makani S, Crawford J, Martinez-Capolino C, Martin G, Tomlanovich M. The Chain of Survival: Is It Time for a Fifth Link? Annals Of Emergency Medicine 2005, 46: 17. DOI: 10.1016/j.annemergmed.2005.06.067.
• SURROGATE MARKERS FOR LACTIC ACIDOSIS IN PATIENTS WITH SEVERE SEPSIS AND SEPTIC SHOCKwira C, Rivers E, Donnino M, Shirazi E, Goyal N, Tomlanovich M. SURROGATE MARKERS FOR LACTIC ACIDOSIS IN PATIENTS WITH SEVERE SEPSIS AND SEPTIC SHOCK. Critical Care Medicine 2004, 32: a151. DOI: 10.1097/00003246-200412001-00538.
• ASSESSMENT OF BLOOD CULTURE COLLECTION TECHNIQUE: A SILENT QUALITY ASSURANCE CRISISDonnino M, Rivers E, Floyd K, Terlicki T, Goyal N, Coggins P, Wira C, Tomlanovich M. ASSESSMENT OF BLOOD CULTURE COLLECTION TECHNIQUE: A SILENT QUALITY ASSURANCE CRISIS. Critical Care Medicine 2004, 32: a68. DOI: 10.1097/00003246-200412001-00251.
• Early goal-directed therapy in patients with end-stage renal diseaseDonnino M, Shirazi E, Wira C, Nguyen B, Jacobsen G, Floyd K, Rivers E. Early goal-directed therapy in patients with end-stage renal disease. Critical Care 2004, 8: p163. PMCID: PMC4099750, DOI: 10.1186/cc2630.