The central goal of my research is the early classification of brain injury severity, identification of secondary brain injury risk profiles, individualized brain-centered resuscitation to minimize secondary brain injury, and neuroprognostication in patients with hypoxic ischemic brain injury.
1. I am the site PI for the Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (ICECAP) trial, aimed at identifying the optimal duration of cooling to 33C in cardiac arrest patients.
2. I am the site PI for the Multimodal Outcome CHAracterization after cardiac arrest (MOCHA) study, a multi-site prospective observational trial aimed at improving multimodal prognostication in cardiac arrest survivors.
3. I am the PI on an investigator-initiated proposal to evaluate cerebral pressure autoregulation and individualized blood pressure goals after cardiac arrest, using near infrared spectroscopy.
4. I am the PI on an industry sponsored pilot grant to evaluate synaptic density in survivors of cardiac arrest, using SV2A PET.
Brain Death; Out-of-Hospital Cardiac Arrest; Post-Cardiac Arrest Syndrome