Skip to Main Content

INFORMATION FOR

Kevin Sheth, MD

Professor of Neurology and Neurosurgery; Executive Director of the NNCTU and Vice Chair for Clinical and Translational Research in the Departments of Neurology and Neurosurgery; Division Chief, Neurocritical Care and Emergency Neurology

Research Summary

Dr. Sheth's research focuses on the identification and translation of new therapies for patients with acute neurological injury such as stroke, brain hemorrhage, and trauma. The primary goal of his group is to identify and translate innovative approaches to improved patient care, using clinical trials in neurological disease as a platform. His group has special expertise in identifying unique patient populations (large and small) using population, genomic, and other big data, collaborating with preclinical labs to prepare pharmacotherapy for translation (including drug delivery), and advancing biomarkers and outcomes that facilitate the detection of clinically relevant treatment effect. This work is aimed primarily towards patients with all forms of cerebrovascular disease including the prevention, acute treatment, and recovery of ischemic and hemorrhagic stroke.

Specialized Terms: Brain edema; Stroke; Intracranial hemorrhage; Neurocritical Care; Critical care; Prognosis; Biomarkers; Clinical Trials

Extensive Research Description

Representative Projects

Pre-Clinical

co-Principal Investigator, “Improved Glyburide Therapy Via Acid-Triggered Release Functional Nanoparticles,” (R01NS110721-01A1) - Together with Dr. Jiangbing Zhou, we are developing novel nanoparticle formulations for treatment of acute ischemic stroke. These nanoparticle have unique structural and composition profiles tailored for acute brain injury and have been developed for a number of candidate treatments, as well as penetration and engagement across the blood-brain-barrier.

co-investigator, “Yale Site for Stroke Preclinical Assessment Network (SPAN) for Acute Neuroprotection,” UO1NS113445 - Together with Dr. Lauren Sansing, we are participating in a multi-center preclinical ischemia-reperfusion stroke model network aimed at identifying candidate therapies for stroke translation.

Clinical Trials

Prevention

co-Investigator, Director of the Recruitment Core Lab, “ARCADIA-CSI (Cognition and Silent Infarcts),” U01NS110728 - Together with Dr. Maarten Lansberg at Stanford, this study will evaluate the role of silent brain infarction on functional and cognitive outcome after stroke caused by cardioembolism. It will also provide information on whether or not anticoagulation may modify this outcome.

co-Principal Investigator, “Anticoagulation in ICH Survivors for Prevention and Recovery (ASPIRE)”, NINDS, U01NS106513 - Together with Dr. Hooman Kamel at Cornell, I am leading this phase III StrokeNet clinical trial which will enroll 700 patients at 125 US centers who survive intracerebral hemorrhage and also have atrial fibrillation. The study will determine whether or not anticoagulation or aspirin results in improved stroke prevention and survival

co-Principal Investigator, “The Recovery in Stroke Using PAP: RISE-UP” Study”, NINR, RO1NR018335 - Together with Dr. Klar Yaggi, this randomized control trial, funded by the NINR, will examine whether or not sleep apnea treatment using positive airway pressure therapy can improve functional outcome and other patient centered symptoms in 180 patients. We will also obtain unique information in this population regarding adherence and qualitative benefit.

Acute Treatment

co-Principal Investigator - INTREPID (Impact of Fever Prevention in Brain Injured Patients) (Sponsor: Bard) - This is a phase III study of over 1000 ischemic and hemorrhagic stroke patients testing the following hypothesis: does fever prevention, using an advanced cooling device, result in improved neurology outcomes in patients with severe stroke.

co-Principal Investigator - Saponimod in Intracerebral Hemorrhage (Sponsor: Novartis) - This is a phase II clinical trial of S1P modulation in patients with spontaneous intracerebral hemorrhage at approximately 20 US sites. We will enroll approximately 60 patients in order to obtain information regarding the feasibility of recruitment, evaluation and administration of S1P modulators and to obtain exploratory information regarding imaging measures of swelling and inflammation and clinical outcomes.

co-Global Lead CHARM (Cirara in Large Hemishperic Infarction Analyzing mRS and Mortality) - The CHARM study is an international, multicenter, randomized, double-blind, placebo-controlled, Phase 3 study that aims to enroll 680 patients with LHI in approximately 20 countries. It will evaluate the efficacy and safety of IV glibenclamide treatment within 10 hours following stroke onset. The primary endpoint is the modified Rankin Scale (mRS), a functional outcome, assessed at 90 days. This trial represents over 10 years of a collaborative translational effort from molecular discovery at the bench to phase III trial in stroke patients who are at high risk for brain swelling.

Recovery

Both the ASPIRE and RISE-UP clinical trials are both prevention and recovery clinical trials in stroke.

Neuroscience Clinical Trial Networks

I am the co-Principal Investigator of 2 NIH Networks in New England.

INFINITY (Investigations For Improved Neurological Treatments at Yale) was selected in 2018 by the National Institutes of Neurological Disorders and Stroke (NINDS) as one of approximately 25 U.S. sites designated to participate in the Network of Excellence in Neuroscience Clinical Trials (NeuroNEXT). This network conducts both biomarker validation and Phase 2 studies of treatment for neurological disease in adults and children through partnerships with academia, private foundations and industry. NeuroNEXT is designed to expand NINDS's capabilty to test the most promising new therapies; increase the efficiency of clinical trials before on embarking on larger studies; and respond quickly as new opportunities arise to test promising treatments for people with neurological disorders. INFINITY is a highly effective research team which includes both adult and pediatric neurologists, neurosurgeons, neuropsychologists, neuroradiologists, and translational scientists committed to conducting high impact clinical trials in neurological diseases.

SPIRIT (Southern New England Partnership In Stroke Research, Innovation and Treatment) was selected in 2018 by the National Institutes of Health (NIH) as one of approximately 25 U.S. Sites designed to participate in StrokeNet. The primary goal of this network is to maximize efficiencies to develop, promote and conduct high-quality, multi-site clinical trials focused on key interventions in stroke prevention, treatment and recovery. The StrokeNet Network is designed to serve as the infrastructure and pipeline for exciting new potential treatments for patients with stroke and those at risk for stroke. SPIRIT is anchored by 3 leading institutes: Yale School of Medicine, Warren Alpert School of Medicine at Brown University, and Hartford Hospital

Engineering and Technology

The nanoparticle project above is in collaboration with biomedical engineering at Yale University.

Principal Investigator, “Portable, Bedside Magnetic Resonance Imaging in Neuroscience”, Hyperfine, Inc and American Heart Association - In collaboration with Dr. W.T. Kimberly and Matthew Rosen at Harvard and with Hyperfine, we have developed and deployed the first portable, bedside MRI in the world.

Data Resources and Repository

My group works with a number of "big data" resources, including publicly available clinical trial datasets (e.g. NIH), administrative and claims datasets (e.g., Nationwide Inpatient Sample, Medicare, Healthcare Utilization Project), quality improvement (AHA-Get With the Guidelines), genomics (e.g. UK Biobank) to make and replicate clinically relevant observations and to understand current practice patterns.

co-Principal Investigator, “Intensive Blood Pressure Reduction in Deep Intracerebral Hemorrhage,” RO3NS112859 - This project examines the role of neuroanatomical location and treatment effect in prior clinical trial and observational series of patients with brain hemorrhage.

Mentorship

Our group fosters the development of academic investigators in clinical and translational research in brain injury from the undergraduate to the faculty level. The focus is on the themes and patient populations identified above.

Coauthors

Research Interests

Biotechnology; Brain Edema; Neurology; Neurosciences; Neurosurgery; Primary Prevention; Quality of Health Care; Subarachnoid Hemorrhage; Drug Delivery Systems; Trauma, Nervous System; Brain Hemorrhage, Traumatic; Infarction, Middle Cerebral Artery; Brain Infarction; Stroke; Biomarkers, Pharmacological; Secondary Prevention

Public Health Interests

Biomarkers; Cardiovascular Diseases; Clinical Guidelines; Clinical Trials; End-of-life Care; Ethics; Health Care Management; e-Health

Selected Publications

  • Temporal profiles of systolic blood pressure variability and neurologic outcomes after endovascular thrombectomyPrasad A, Kobsa J, Kodali S, Bartolome D, Begunova L, Quispe-Orozco D, Farooqui M, Zevallos C, Ortega-Gutiérrez S, Anadani M, Almallouhi E, Spiotta A, Giles J, Keyrouz S, Kim J, Maier I, Liman J, Psychogios M, Riou-Comte N, Richard S, Gory B, Wolfe S, Quintero Wolfe S, Brown P, Fargen K, Mistry E, Fakhri H, Mistry A, Wong K, Nascimento F, Kan P, de Havenon A, Sheth K, Petersen N. Temporal profiles of systolic blood pressure variability and neurologic outcomes after endovascular thrombectomy European Stroke Journal 2022, 239698732211069. DOI: 10.1177/23969873221106907.
  • 445-P: CV Risk Factor Control in Patients with T2D and Coronary Artery Disease vs. StrokeBALASUBRAMANIAN P, KERNAN W, SHETH K, OFSTAD A, MATTHEUS M, MARX N, INZUCCHI S. 445-P: CV Risk Factor Control in Patients with T2D and Coronary Artery Disease vs. Stroke Diabetes 2022, 71 DOI: 10.2337/db22-445-p.
  • Blood Pressure and Low‐Density Lipoprotein Cholesterol in Stroke Survivors Versus Controls in the United States From 1999 to 2018Havenon A, Prabhakaran S, Stulberg E, McLean K, Johnston K, Lansberg M, Grory B, Tirschwell D, Majersik J, Ney J, Sharma R, Sheth K. Blood Pressure and Low‐Density Lipoprotein Cholesterol in Stroke Survivors Versus Controls in the United States From 1999 to 2018 Stroke Vascular And Interventional Neurology 2022, 2 DOI: 10.1161/svin.121.000286.
  • WORSE VASCULAR RISK FACTOR CONTROL IN PATIENTS WITH STROKE COMPARED TO PATIENTS WITH MYOCARDIAL INFARCTIONLeasure A, Acosta J, Schwartz A, Forman R, Sharma R, de Havenon A, Falcone G, Inzucchi S, Kernan W, Sheth K. WORSE VASCULAR RISK FACTOR CONTROL IN PATIENTS WITH STROKE COMPARED TO PATIENTS WITH MYOCARDIAL INFARCTION Journal Of The American College Of Cardiology 2022, 79: 1504. DOI: 10.1016/s0735-1097(22)02495-0.
  • Abstract 67: Observed And Genomic Life’S Simple 7 Influence Brain Health-related Neuroimaging Traits In Persons Without Stroke Or DementiaAcosta J, Both C, Rivier C, Leasure A, Gill T, Payabvash S, Sheth K, Falcone G. Abstract 67: Observed And Genomic Life’S Simple 7 Influence Brain Health-related Neuroimaging Traits In Persons Without Stroke Or Dementia Stroke 2022, 53: a67-a67. DOI: 10.1161/str.53.suppl_1.67.
  • Abstract 103: Burden Of Ischemic And Hemorrhagic Stroke Across The Us From 1990-2019: A Global Burden Of Disease StudyLeasure A, Acosta J, Sharma R, Krumholz H, de Havenon A, Falcone G, Sheth K. Abstract 103: Burden Of Ischemic And Hemorrhagic Stroke Across The Us From 1990-2019: A Global Burden Of Disease Study Stroke 2022, 53: a103-a103. DOI: 10.1161/str.53.suppl_1.103.
  • Abstract 107: Effect Of Intensive Blood Pressure Control On Incident Stroke Risk In Patients With Mild Cognitive Impairmentde Havenon A, Sharma R, Falcone G, Prabhakaran S, Sheth K. Abstract 107: Effect Of Intensive Blood Pressure Control On Incident Stroke Risk In Patients With Mild Cognitive Impairment Stroke 2022, 53: a107-a107. DOI: 10.1161/str.53.suppl_1.107.
  • Abstract 9: Pervasive White Matter Microstructure Dysintegrity Related To High Blood Pressure Among Asymptomatic PopulationAcosta J, Haider S, Rivier C, Leasure A, Sheth K, Falcone G, Payabvash S. Abstract 9: Pervasive White Matter Microstructure Dysintegrity Related To High Blood Pressure Among Asymptomatic Population Stroke 2022, 53: a9-a9. DOI: 10.1161/str.53.suppl_1.9.
  • Abstract 123: Carotid Artery Stenosis In Underrepresented Populations Defined By Factors Other Than Race/ethnicity: Results From All Of UsRenedo D, Acosta J, Sheth K, Matouk C, Falcone G. Abstract 123: Carotid Artery Stenosis In Underrepresented Populations Defined By Factors Other Than Race/ethnicity: Results From All Of Us Stroke 2022, 53: a123-a123. DOI: 10.1161/str.53.suppl_1.123.
  • Abstract TMP22: Genetic Predisposition To Cardiovascular Disease Is Associated With Higher Risk Of Stroke In Persons With COVID-19Both C, Both C, Abdelhakim S, Acosta J, Acosta J, Szejko N, Szejko N, Leasure A, Leasure A, Jasne A, Sharma R, Sharma R, Sheth K, Falcone G. Abstract TMP22: Genetic Predisposition To Cardiovascular Disease Is Associated With Higher Risk Of Stroke In Persons With COVID-19 Stroke 2022, 53: atmp22-atmp22. DOI: 10.1161/str.53.suppl_1.tmp22.
  • Abstract 71: Cognitive Impairment And The Risk Of Incident Stroke In Hypertensive Patientsde Havenon A, Sharma R, Falcone G, Sheth K. Abstract 71: Cognitive Impairment And The Risk Of Incident Stroke In Hypertensive Patients Stroke 2022, 53: a71-a71. DOI: 10.1161/str.53.suppl_1.71.
  • Abstract WMP81: Association Between Systemic Amyloidosis And Intracranial HemorrhageChen D, Zhang C, Jalil S, Parikh N, Merkler A, Fink M, Gupta A, Sheth K, Falcone G, Navi B, Kamel H, Murthy S. Abstract WMP81: Association Between Systemic Amyloidosis And Intracranial Hemorrhage Stroke 2022, 53: awmp81-awmp81. DOI: 10.1161/str.53.suppl_1.wmp81.
  • Abstract WP178: Biological Age Influences Clinically-evident And Asymptomatic Cerebrovascular Disease: Combined Analysis In The Uk Biobank And All Of UsRivier C, Szejko N, Acosta J, Both C, Leasure A, Lopez V, Gill T, Sheth K, Falcone G. Abstract WP178: Biological Age Influences Clinically-evident And Asymptomatic Cerebrovascular Disease: Combined Analysis In The Uk Biobank And All Of Us Stroke 2022, 53: awp178-awp178. DOI: 10.1161/str.53.suppl_1.wp178.
  • Abstract TP134: Association Of Neutrophil-lymphocyte Ratio With Functional Outcome In Spontaneous Intracerebral HemorrhageAtillasoy J, Leasure A, Schwartz A, Reznik M, Moody S, Bevers M, Matouk C, Falcone G, Sansing L, Kimberly W, Sheth K. Abstract TP134: Association Of Neutrophil-lymphocyte Ratio With Functional Outcome In Spontaneous Intracerebral Hemorrhage Stroke 2022, 53: atp134-atp134. DOI: 10.1161/str.53.suppl_1.tp134.
  • Abstract WP191: Genetic Analyses Support A Causal Role Of Lung Cancer In Ischemic StrokeVanent K, Acosta J, Both C, Leasure A, Lopez V, Szejko N, Rivier C, de Havenon A, Sharma R, Levitt M, Sheth K, Falcone G. Abstract WP191: Genetic Analyses Support A Causal Role Of Lung Cancer In Ischemic Stroke Stroke 2022, 53: awp191-awp191. DOI: 10.1161/str.53.suppl_1.wp191.
  • Abstract 105: Polygenic Burden Of Hypertension-related Alleles Leads To Non-traumatic Subarachnoid Hemorrhage At Younger AgesVanent K, Acosta J, Both C, Leasure A, Noche R, Levitt M, Matouk C, Gunel M, Sheth K, Falcone G. Abstract 105: Polygenic Burden Of Hypertension-related Alleles Leads To Non-traumatic Subarachnoid Hemorrhage At Younger Ages Stroke 2022, 53: a105-a105. DOI: 10.1161/str.53.suppl_1.105.
  • Abstract WP111: Deployment Of Portable, Bedside, Low-field Magnetic Resonance Imaging In The Emergency Department To Evaluate Patients With Acute StrokeChavva I, Mazurek M, Yuen M, Prabhat A, Crawford A, Cahn B, Schindler J, Sansing L, Matouk C, Hebert R, de Havenon A, Sharma R, Payabvash S, Sze G, Aydin A, Parwani V, Ulrich A, Brown K, Sheth K, Wira C. Abstract WP111: Deployment Of Portable, Bedside, Low-field Magnetic Resonance Imaging In The Emergency Department To Evaluate Patients With Acute Stroke Stroke 2022, 53: awp111-awp111. DOI: 10.1161/str.53.suppl_1.wp111.
  • Abstract 89: Nimodipine-induced Blood Pressure Reductions Below Personalized Limits Of Autoregulation Are Associated With Worse Outcomes After Subarachnoid HemorrhageBartolome D, Begunova Y, Prasad A, Soto A, Kobsa J, Top I, Quispe-Orozco D, Farooqui M, Zevallos C, Kim J, Gilmore E, Beekman R, de Havenon A, Matouk C, Sheth K, Ortega-Gutierrez S, Petersen N. Abstract 89: Nimodipine-induced Blood Pressure Reductions Below Personalized Limits Of Autoregulation Are Associated With Worse Outcomes After Subarachnoid Hemorrhage Stroke 2022, 53: a89-a89. DOI: 10.1161/str.53.suppl_1.89.
  • Abstract TMP55: Post-stroke Blood Pressure Variability In The Acute Phase Is Associated With Pre-stroke Blood Pressure Variability In Patients Undergoing Mechanical ThrombectomySoto A, Prasad A, Kobsa J, Bartolome D, Begunova Y, Kodali S, Quispe-Orozco D, Farooqui M, Zevallos C, Sansing L, Schindler J, Matouk C, Sheth K, de Havenon A, Ortega-Gutierrez S, Petersen N. Abstract TMP55: Post-stroke Blood Pressure Variability In The Acute Phase Is Associated With Pre-stroke Blood Pressure Variability In Patients Undergoing Mechanical Thrombectomy Stroke 2022, 53: atmp55-atmp55. DOI: 10.1161/str.53.suppl_1.tmp55.
  • Abstract WP218: Midlife Blood Pressure Trajectory And Later Life Risk Of Ischemic Stroke: A Post-hoc Analysis Of ARICde Havenon A, Yaghi S, Anadani M, Mistry E, Petersen N, Prabhakaran S, Lansberg M, Sheth K. Abstract WP218: Midlife Blood Pressure Trajectory And Later Life Risk Of Ischemic Stroke: A Post-hoc Analysis Of ARIC Stroke 2022, 53: awp218-awp218. DOI: 10.1161/str.53.suppl_1.wp218.
  • Abstract 91: Large Vessel Occlusion Stroke Patients With Rapid Early Infarct Progression And Poor Collaterals Are Vulnerable To Blood Pressure ReductionsBegunova Y, Bartolome D, Kobsa J, Prasad A, Soto A, Quispe-Orozco D, Farooqui M, Zevallos C, Sansing L, Schindler J, De Havenon A, Matouk C, Sheth K, Ortega-Gutierrez S, Petersen N. Abstract 91: Large Vessel Occlusion Stroke Patients With Rapid Early Infarct Progression And Poor Collaterals Are Vulnerable To Blood Pressure Reductions Stroke 2022, 53: a91-a91. DOI: 10.1161/str.53.suppl_1.91.
  • Abstract WP224: Trends In Self-reported Stroke And Myocardial Infarction Prevalence And Associated Modifiable Risk Factors Within Race/ethnicity Strata In The United States From 2011-2019de Havenon A, Heath T, Johnston K, Sharma R, Wong K, Yaghi S, NEY J, Sheth K. Abstract WP224: Trends In Self-reported Stroke And Myocardial Infarction Prevalence And Associated Modifiable Risk Factors Within Race/ethnicity Strata In The United States From 2011-2019 Stroke 2022, 53: awp224-awp224. DOI: 10.1161/str.53.suppl_1.wp224.
  • Abstract TMP21: Impact Of COVID-19 State-level Hospital Capacity On Overall Stroke Mortality In 2020 In The United Statesde Havenon A, Yaghi S, Stulberg E, Delic A, Anadani M, Sheth K, Majersik J. Abstract TMP21: Impact Of COVID-19 State-level Hospital Capacity On Overall Stroke Mortality In 2020 In The United States Stroke 2022, 53: atmp21-atmp21. DOI: 10.1161/str.53.suppl_1.tmp21.
  • Abstract TP142: Platelet Count And Intracerebral Hemorrhage Expansion In The ATACH 2 TrialAnadani M, Qureshi A, Sheth K, Yaghi S, de Havenon A. Abstract TP142: Platelet Count And Intracerebral Hemorrhage Expansion In The ATACH 2 Trial Stroke 2022, 53: atp142-atp142. DOI: 10.1161/str.53.suppl_1.tp142.
  • Abstract WP215: Population Attributable Risks For Potentially Modifiable Risk Factors Of Cerebrovascular And Cardiovascular-related Mortality In The National Health And Nutrition Examination SurveySharma R, Baker A, Mszar R, Leasure A, Khera R, de Havenon A, Lu Y, Jasne A, Forman R, Sheth K, Krumholz H, Sharma R. Abstract WP215: Population Attributable Risks For Potentially Modifiable Risk Factors Of Cerebrovascular And Cardiovascular-related Mortality In The National Health And Nutrition Examination Survey Stroke 2022, 53: awp215-awp215. DOI: 10.1161/str.53.suppl_1.wp215.
  • Abstract 106: Twenty Year Trends In US Stroke Mortality In Younger Vs Older Adultsde Havenon A, Majersik J, Leasure A, Delic A, Tirschwell D, Sheth K. Abstract 106: Twenty Year Trends In US Stroke Mortality In Younger Vs Older Adults Stroke 2022, 53: a106-a106. DOI: 10.1161/str.53.suppl_1.106.
  • Abstract 46: Effect Of Intravenous Alteplase On Ischemic Stroke Mortality Is Dependent On Stroke Severityde Havenon A, Sheth K, Sultan-qurraie A, Tirschwell D. Abstract 46: Effect Of Intravenous Alteplase On Ischemic Stroke Mortality Is Dependent On Stroke Severity Stroke 2022, 53: a46-a46. DOI: 10.1161/str.53.suppl_1.46.
  • Abstract 99: Single Cell RNA-Sequencing Reveals Array Of Immune Activation States In Intracerebral HemorrhageJohnson C, Askenase M, Beatty H, DeLong J, Zhang L, Sheth K, Cord B, Hebert R, Matouk C, Sansing L. Abstract 99: Single Cell RNA-Sequencing Reveals Array Of Immune Activation States In Intracerebral Hemorrhage Stroke 2022, 53: a99-a99. DOI: 10.1161/str.53.suppl_1.99.
  • Abstract TP188: Predicting Ischemic Stroke And All-cause Mortality Risk In Patients With Heart Failure With Reduced Ejection Fraction And Sinus Rhythm: A Secondary Analysis Of The Warcef TrialSharma R, Krumholz H, Sheth K, Faridi K, Kamel H, Merkler A, Sharma R. Abstract TP188: Predicting Ischemic Stroke And All-cause Mortality Risk In Patients With Heart Failure With Reduced Ejection Fraction And Sinus Rhythm: A Secondary Analysis Of The Warcef Trial Stroke 2022, 53: atp188-atp188. DOI: 10.1161/str.53.suppl_1.tp188.
  • Abstract WMP79: Elevated Cardiac Troponin Levels In Patients With Non-traumatic Intracerebral HemorrhageKim J, Sekar P, Castillo N, Langefeld C, Hillmann M, Birnbaum L, Sheth K, Flaherty M, Woo D, Testai F. Abstract WMP79: Elevated Cardiac Troponin Levels In Patients With Non-traumatic Intracerebral Hemorrhage Stroke 2022, 53: awmp79-awmp79. DOI: 10.1161/str.53.suppl_1.wmp79.
  • Abstract TP213: Arcadia CSI (Cognition And Silent Infarcts): UpdateLazar R, Lansberg M, Howard G, Sheth K, Tirschwell D, Wintermark M, Harris T, Myers T, KEMP S, Cassarly C, Broderick J, Kamel H, Elkind M. Abstract TP213: Arcadia CSI (Cognition And Silent Infarcts): Update Stroke 2022, 53: atp213-atp213. DOI: 10.1161/str.53.suppl_1.tp213.
  • Abstract TP20: Intravenous Glibenclamide For Large Hemispheric Infarction: Baseline Data From Initial Enrollees In The Charm Phase 3 StudySheth K, Kimberly W, Albers G, Campbell B, Cordonnier C, Hinson H, Molyneaux B, Nogueira R, Saver J, Steiner T, Toyoda K, Wintermark M, Hareedy R, Wald M, Zhang R, Ziogas N, Rizzo M. Abstract TP20: Intravenous Glibenclamide For Large Hemispheric Infarction: Baseline Data From Initial Enrollees In The Charm Phase 3 Study Stroke 2022, 53: atp20-atp20. DOI: 10.1161/str.53.suppl_1.tp20.
  • 56 Critical Care of the Patient With Acute StrokePicard J, Schmidt C, Sheth K, Bösel J. 56 Critical Care of the Patient With Acute Stroke 2022, 800-830.e10. DOI: 10.1016/b978-0-323-69424-7.00056-9.
  • Race/Ethnicity Considerations in the Prevention and Treatment of StrokeForman R, Sheth K. Race/Ethnicity Considerations in the Prevention and Treatment of Stroke Current Treatment Options In Neurology 2021, 23: 33. DOI: 10.1007/s11940-021-00684-2.
  • Author Response: Cause of Death in Spontaneous Intracerebral Hemorrhage Survivors: Multistate Longitudinal StudyKuohn L, Sheth K. Author Response: Cause of Death in Spontaneous Intracerebral Hemorrhage Survivors: Multistate Longitudinal Study Neurology 2021, 97: 149.1-149. DOI: 10.1212/wnl.0000000000012283.
  • Abstract P41: Integrating Demographics, TCD and EEG Diagnostic Modalities Improves Delayed Cerebral Ischemia Prediction After Subarachnoid HemorrhageChen H, Elmer J, Ghanta M, Valdery-Moura J, Zahar S, Rosenthal E, Gilmore E, Hirsch L, Zaveri H, Sheth K, Petersen N, Westover M, Kim J. Abstract P41: Integrating Demographics, TCD and EEG Diagnostic Modalities Improves Delayed Cerebral Ischemia Prediction After Subarachnoid Hemorrhage Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p41.
  • Abstract 33: Qualitative Description of Ischemic Stroke Appearance on Low-Field, Point-Of-Care Magnetic Resonance ImagingYuen M, Mazurek M, Cahn B, Prabhat A, By S, Hu H, Welch E, Sacolick L, O’Halloran R, Ward A, Timario N, Falcone G, Gilmore E, Hwang D, Kim J, Kaddouh F, Sharma R, Amin H, Schindler J, Matouk C, Hebert R, Wira C, Sze G, Rosen M, Kimberly W, Sheth K. Abstract 33: Qualitative Description of Ischemic Stroke Appearance on Low-Field, Point-Of-Care Magnetic Resonance Imaging Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.33.
  • Abstract MP13: Polygenic Susceptibility to Atrial Fibrillation is Associated With Silent Cerebrovascular Disease in Stroke-Free Persons Without Atrial FibrillationBoth C, Acosta J, Szejko N, Vanent K, Leasure A, Payabvash S, Sharma R, Murthy S, Sheth K, Kamel H, Falcone G. Abstract MP13: Polygenic Susceptibility to Atrial Fibrillation is Associated With Silent Cerebrovascular Disease in Stroke-Free Persons Without Atrial Fibrillation Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.mp13.
  • Abstract MP40: Klotho -vS Heterozygosity is Associated With Lower Risk of Lobar Intracerebral HemorrhageAcosta J, Szejko N, Both C, Leasure A, Woo D, Langefeld C, Biffi A, Anderson C, Rosand J, Gill T, Sansing L, Sheth K, Falcone G. Abstract MP40: Klotho -vS Heterozygosity is Associated With Lower Risk of Lobar Intracerebral Hemorrhage Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.mp40.
  • Abstract MP53: Intensive Blood Pressure Reduction and Secondary Stroke Risk: A Posthoc Analysis of the Sps3 Trialde Havenon A, Lansberg M, Falcone G, Noche R, Yaghi S, Sheth K. Abstract MP53: Intensive Blood Pressure Reduction and Secondary Stroke Risk: A Posthoc Analysis of the Sps3 Trial Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.mp53.
  • Abstract P410: Association of Serum GFAP With Hematoma Expansion and Poor Outcome After Intracerebral Hemorrhage: The Factor VII for ICH TrialLeasure A, Vanent K, Bevers M, Kimberly W, Mayer S, Steiner T, Matouk C, Sansing L, Falcone G, Sheth K. Abstract P410: Association of Serum GFAP With Hematoma Expansion and Poor Outcome After Intracerebral Hemorrhage: The Factor VII for ICH Trial Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p410.
  • Abstract P412: Klotho -vS Heterozygosity is Associated With Lower Risk of Non-Traumatic Subarachnoid HemorrhageAcosta J, Szejko N, Torres Lopez V, Both C, Sansing L, Sheth K, Matouk C, Gunel M, Falcone G. Abstract P412: Klotho -vS Heterozygosity is Associated With Lower Risk of Non-Traumatic Subarachnoid Hemorrhage Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p412.
  • Abstract P423: Race and Ethnicity Influence Perihematomal Edema Volume in Supratentorial Intracerebral HemorrhageAcosta J, Chen Y, Both C, Leasure A, Testai F, Woo D, Lee J, Sheth K, Dhar R, Falcone G. Abstract P423: Race and Ethnicity Influence Perihematomal Edema Volume in Supratentorial Intracerebral Hemorrhage Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p423.
  • Abstract P439: Mortality After an Arterial Ischemic Event Among Intracerebral Hemorrhage SurvivorsParasram M, Parikh N, Merkler A, Falcone G, Sheth K, Navi B, Kamel H, Zhang C, Murthy S. Abstract P439: Mortality After an Arterial Ischemic Event Among Intracerebral Hemorrhage Survivors Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p439.
  • Abstract P510: Ct Angiographic Radiomics Signature Predicts Functional Outcome Following Endovascular Thrombectomy in Large Vessel Occlusion StrokeAvery E, Behland J, Haider S, Zeevi T, Nguyen C, Peshwe K, Petersen N, Falcone G, Sansing L, Malhotra A, Matouk C, Sheth K, Payabvash S. Abstract P510: Ct Angiographic Radiomics Signature Predicts Functional Outcome Following Endovascular Thrombectomy in Large Vessel Occlusion Stroke Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p510.
  • Abstract P622: Racial Variation in White Matter Hyperintensity Progression in the ACCORDION MIND StudyHerman A, De Havenon A, Falcone G, Yaghi S, Prabhakaran S, Sheth K. Abstract P622: Racial Variation in White Matter Hyperintensity Progression in the ACCORDION MIND Study Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p622.
  • Abstract P629: Genome-Wide Association Study of Individuals of Native Hawaiian Ancestry Reveals Unique Genetic Risk Factors for Stroke and Myocardial InfarctionBrown S, Both C, Acosta J, Szejko N, Torres V, Leasure A, Nakagawa K, Gerschenson M, Seto T, Sheth K, Falcone G. Abstract P629: Genome-Wide Association Study of Individuals of Native Hawaiian Ancestry Reveals Unique Genetic Risk Factors for Stroke and Myocardial Infarction Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p629.
  • Abstract P633: Polygenic Susceptibility to Hypertension is Associated With Uncontrolled and Resistant Hypertension in Stroke SurvivorsAcosta J, Both C, Szejko N, Brown S, Petersen N, Sansing L, Sheth K, Falcone G. Abstract P633: Polygenic Susceptibility to Hypertension is Associated With Uncontrolled and Resistant Hypertension in Stroke Survivors Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p633.
  • Abstract P879: Differences in Statistical Performance of Polygenic Risk Scores for Cardiovascular Disease Across Different Race/EthnicitiesAcosta J, Both C, Szejko N, Brown S, Sheth K, Falcone G. Abstract P879: Differences in Statistical Performance of Polygenic Risk Scores for Cardiovascular Disease Across Different Race/Ethnicities Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p879.
  • Abstract P91: Excess Cerebrovascular Mortality in the U.S. During the Covid-19 PandemicSharma R, Kuohn L, Weinberger D, Warren J, Sansing L, Jasne A, Falcone G, Dhand A, Sheth K. Abstract P91: Excess Cerebrovascular Mortality in the U.S. During the Covid-19 Pandemic Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p91.
  • Abstract P384: Outcomes of Endovascular Therapy in Patients With Pre-Stroke Mobility ImpairmentBeekman R, Sun J, Alhanti B, Schwamm L, Smith E, Bhatt D, Xian Y, Shah S, Lytle B, Fonarow G, Sheth K. Abstract P384: Outcomes of Endovascular Therapy in Patients With Pre-Stroke Mobility Impairment Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p384.
  • Abstract MP33: Association Between Neurologic Outcomes and Temporal Profile of Systolic Blood Pressure Variability After Endovascular ThrombectomyPrasad A, Kobsa J, Kodali S, Nguyen C, Quispe Orozco D, Farooqui M, Zevallos C, Ortega S, Anadani M, Almallouhi E, Giles J, Spiotta A, Kim J, Maier I, Psychogios M, Liman J, Riou-Comte N, Richard S, Gory B, Wolfe S, Brown P, Fargen K, Mistry E, Fakhri H, Mistry A, Wong K, De Havenon A, Nascimento F, Kan P, Sheth K, Petersen N. Abstract MP33: Association Between Neurologic Outcomes and Temporal Profile of Systolic Blood Pressure Variability After Endovascular Thrombectomy Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.mp33.
  • Abstract P649: Extracranial Hemorrhage in the Setting of Gastrointestinal Or Genitourinary Cancer is Associated With Increased Risk of Ischemic Stroke in Patients With Atrial FibrillationZhou E, Lord A, Boehme A, Henninger N, De Havenon A, Vahidy F, Ishida K, Torres J, Mistry E, Mac Grory B, Sheth K, Gurol E, Furie K, Elkind M, Yaghi S. Abstract P649: Extracranial Hemorrhage in the Setting of Gastrointestinal Or Genitourinary Cancer is Associated With Increased Risk of Ischemic Stroke in Patients With Atrial Fibrillation Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p649.
  • Abstract MP35: Blood Pressure Reductions Before Arrival at a Thrombectomy-Capable Hospital Are Associated With Neurologic Worsening in Patients With Large-Vessel OcclusionKobsa J, Prasad A, Soto A, Kodali S, Nguyen C, Peshwe K, Quispe-Orozco D, Farooqui M, Zeballos C, Sansing L, Schindler J, Matouk C, Sheth K, Ortega-Gutierrez S, Petersen N. Abstract MP35: Blood Pressure Reductions Before Arrival at a Thrombectomy-Capable Hospital Are Associated With Neurologic Worsening in Patients With Large-Vessel Occlusion Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.mp35.
  • Abstract MP36: Blood Pressure Reductions in the Hyperacute Phase of Large Vessel Occlusion Ischemic Stroke Are Associated With Infarct Progression and Poor Functional OutcomePeshwe K, Nguyen C, Kodali S, Kobsa J, Prasad A, Soto A, Wira C, Matouk C, Sheth K, Petersen N. Abstract MP36: Blood Pressure Reductions in the Hyperacute Phase of Large Vessel Occlusion Ischemic Stroke Are Associated With Infarct Progression and Poor Functional Outcome Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.mp36.
  • Abstract 65: Targeted Drug Delivery via Acid-Triggered Release Antioxidant Nanoparticles Improves Efficacy of Na1 for Stroke TreatmentZhang S, Chen Z, Deng G, Kimberly W, Simard J, Zhou J, Sheth K. Abstract 65: Targeted Drug Delivery via Acid-Triggered Release Antioxidant Nanoparticles Improves Efficacy of Na1 for Stroke Treatment Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.65.
  • Abstract P133: Geospatial Mapping of Prehospital Delay in Acute Ischemic Stroke and Association With Social VulnerabilityDhand A, Nieves A, Jarman M, Bergmark R, Semco R, Ader J, Fonarow G, Smith E, Reeves M, Saver J, Schwamm L, Sheth K. Abstract P133: Geospatial Mapping of Prehospital Delay in Acute Ischemic Stroke and Association With Social Vulnerability Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p133.
  • Abstract P677: Ischemic Stroke, Depressed Ejection Fraction, and Sinus Rhythm: Prevalence, Practice Patterns, and OutcomesSharma R, Sugeng L, Sheth K, Jasne A, Baker A, Mac Grory B, Stretz C, Furie K, yaghi S, Schwamm L, Kleindorfer D, Sucharew H, Coleman E, Mackey J, Walsh K, Flaherty M, Haverbusch M, De Los Rios La Rosa F. Abstract P677: Ischemic Stroke, Depressed Ejection Fraction, and Sinus Rhythm: Prevalence, Practice Patterns, and Outcomes Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p677.
  • 30-Day Outcomes of Trans-Carotid Artery Revascularization with Proximal Protection Through ICA Flow Reversal in Neurosurgical PracticeCord B, Santarosa C, Sujijantarat N, Koo A, Elsamadicy A, Sheth K, Falcone G, Sansing L, Schindler J, Petersen N, Matouk C. 30-Day Outcomes of Trans-Carotid Artery Revascularization with Proximal Protection Through ICA Flow Reversal in Neurosurgical Practice Neurosurgery 2020, 67 DOI: 10.1093/neuros/nyaa447_334.
  • Obstructive Sleep Apnea: A Prevalent and Novel Risk Factor for Intracerebral HemorrhageGeer J, Vanent K, Leasure A, Pisani M, Sansing L, Woo D, Langefeld C, Falcone G, Sheth K, Yaggi H. Obstructive Sleep Apnea: A Prevalent and Novel Risk Factor for Intracerebral Hemorrhage 2020, a2713-a2713. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2713.
  • Abstract 117: Fixed Compared to Autoregulation-oriented Blood Pressure Thresholds After Mechanical Thrombectomy for Ischemic StrokePetersen N, Silverman A, Strander S, Kodali S, Wang A, Sansing L, Schindler J, Falcone G, Gilmore E, Jasne A, Cord B, Hebert R, Johnson M, Matouk C, Sheth K. Abstract 117: Fixed Compared to Autoregulation-oriented Blood Pressure Thresholds After Mechanical Thrombectomy for Ischemic Stroke Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.117.
  • Abstract 156: Recurrent Stroke in Middle-Aged Lacunar Stroke Survivors: Understanding Risk Factors and Vulnerability in an Important Target PopulationNoche R, Biffi A, Sansing L, Shoamanesh A, Benavente O, Falcone G, Sheth K. Abstract 156: Recurrent Stroke in Middle-Aged Lacunar Stroke Survivors: Understanding Risk Factors and Vulnerability in an Important Target Population Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.156.
  • Abstract 18: Diffusion Weighted Imaging Lesions in Patients With Acute Intracerebral Hemorrhage: A Pooled Analysis of Individual Patient Data From MISTIE-III, ATACH-II, I-DEF, and ERICHMurthy S, Cho S, Gupta A, Shoamanesh A, Avadhani R, Gruber J, Greige T, Lioutas V, Norton C, Mandava P, Falcone G, Sheth K, Qureshi A, Goldstein J, Kidwell C, Selim M, Woo D, Kamel H, Ziai W, Hanley D. Abstract 18: Diffusion Weighted Imaging Lesions in Patients With Acute Intracerebral Hemorrhage: A Pooled Analysis of Individual Patient Data From MISTIE-III, ATACH-II, I-DEF, and ERICH Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.18.
  • Abstract 57: Deployment of Portable, Bedside, Low-Field Magnetic Resonance Imaging for Evaluation of Stroke PatientsCahn B, Shah J, Dyvorne H, O'Halloran R, Poole M, Yuen M, Mazurek M, Ward A, Payabvash S, Beekman R, Brown S, Falcone G, Gobeske K, Petersen N, Jasne A, Sharma R, Schindler J, Sansing L, Gilmore E, Wira C, Matouk C, Sze G, Rosen M, Kimberly W, Sheth K. Abstract 57: Deployment of Portable, Bedside, Low-Field Magnetic Resonance Imaging for Evaluation of Stroke Patients Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.57.
  • Abstract 66: Causal Associations Between Genetically-determined Smoking and Risk of Subarachnoid HemorrhageAcosta J, Both C, Brown S, Leasure A, Vanent K, Noche R, Kirsch E, Petersen N, Matouk C, Gunel M, Gill T, Sheth K, Falcone G. Abstract 66: Causal Associations Between Genetically-determined Smoking and Risk of Subarachnoid Hemorrhage Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.66.
  • Abstract 71: Sex and Genetic Predisposition Synergistically Influence Risk of Stroke and Myocardial Infarction in Middle-Aged Persons Without Risk FactorsFalcone G, Acosta J, Leasure A, Vanent K, Noche R, Kirsch E, Petersen N, Schindler J, Sansing L, Gill T, Matouk C, Gunel M, Sheth K. Abstract 71: Sex and Genetic Predisposition Synergistically Influence Risk of Stroke and Myocardial Infarction in Middle-Aged Persons Without Risk Factors Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.71.
  • Abstract TP347: Obstructive Sleep Apnea Frequency in Intracerebral HemorrhageGeer J, Leasure A, Vanent K, Sansing L, Woo D, Langefeld C, Yaggi H, Falcone G, Sheth K. Abstract TP347: Obstructive Sleep Apnea Frequency in Intracerebral Hemorrhage Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tp347.
  • Abstract WMP101: Prediction of Clinical Outcome in Supratentorial Intracerebral Hemorrhage: Application of Baseline Ct Scan Radiomics Feature Extraction and Machine Learning ClassifiersPayabvash S, Acosta J, Haider S, Noche R, Kirsch E, Matouk C, Sansing L, Sheth K, Falcone G. Abstract WMP101: Prediction of Clinical Outcome in Supratentorial Intracerebral Hemorrhage: Application of Baseline Ct Scan Radiomics Feature Extraction and Machine Learning Classifiers Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wmp101.
  • Abstract WP11: Timing of Blood Pressure Decreases During Mechanical Thrombectomy for Ischemic StrokeKimmel A, Silverman A, Kodali S, Strander S, Nguyen C, Peshwe K, Wang A, Lopez G, Holcombe A, Zevallos C, Dandapat S, Sansing L, Schindler J, Falcone G, Matouk C, Sheth K, Ortega-Gutiérrez S, Petersen N. Abstract WP11: Timing of Blood Pressure Decreases During Mechanical Thrombectomy for Ischemic Stroke Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp11.
  • Abstract WP214: Risk Factors for Recurrence of Vascular Events in Middle-Aged Stroke SurvivorsVanent K, Leasure A, Kuohn L, Benavente O, Shoamanesh A, Biffi A, Sheth K, Falcone G. Abstract WP214: Risk Factors for Recurrence of Vascular Events in Middle-Aged Stroke Survivors Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp214.
  • Abstract WP235: Risk of Arterial Ischemic Events After Non-Traumatic Subdural HemorrhageMurthy S, Wu X, Diaz I, Parasram M, Parikh N, Merkler A, Falcone G, Navi B, Sheth K, Kamel H. Abstract WP235: Risk of Arterial Ischemic Events After Non-Traumatic Subdural Hemorrhage Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp235.
  • Abstract WP400: Causes of Death in a Longitudinal Analysis of Spontaneous Intracerebral Hemorrhage SurvivorsKuohn L, Leasure A, Acosta J, Vanent K, Murthy S, Kamel H, Matouk C, Sansing L, Falcone G, Sheth K. Abstract WP400: Causes of Death in a Longitudinal Analysis of Spontaneous Intracerebral Hemorrhage Survivors Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp400.
  • Abstract WP410: Hemoglobin Levels and Poor Outcome in Intracerebral Hemorrhage: An Exploratory Analysis of Individual Patient Data Across Multiple StudiesAcosta J, Leasure A, Kuohn L, Petersen N, Sansing L, Matouk C, Testai F, Langefeld C, Woo D, Qureshi A, Mayer S, Sheth K, Falcone G. Abstract WP410: Hemoglobin Levels and Poor Outcome in Intracerebral Hemorrhage: An Exploratory Analysis of Individual Patient Data Across Multiple Studies Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp410.
  • Abstract 120: Systolic Blood Pressure Trajectories 72 Hours After Mechanical Thrombectomy Are Associated With Poor Functional Outcome: A Multicenter Analysis of Individual Patient Blood Pressure DataKodali S, Meng C, Strander S, Nguyen C, Silverman A, Kimmel A, Peshwe K, Wang A, Anadani M, Spiotta A, de Havenon A, Wong K, Holcombe A, Ortega-Gutiérrez S, Zevallos C, Mistry E, Fakhri H, Mistry A, Tarasaria K, Nouh A, Maier I, Psychogios M, Liman J, Goyal N, Arthur A, Pandhi A, Wolfe S, Nascimento F, Kan P, Riou-Comte N, Gory B, Kim J, Sheth K, Petersen N. Abstract 120: Systolic Blood Pressure Trajectories 72 Hours After Mechanical Thrombectomy Are Associated With Poor Functional Outcome: A Multicenter Analysis of Individual Patient Blood Pressure Data Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.120.
  • Abstract TMP89: Impaired Cerebral Autoregulation Increases Risk of Worse Outcome After Endovascular Thrombectomy in Stroke Patients With High Blood Pressure VariabilityNguyen C, Silverman A, Wang A, Kodali S, Strander S, Kimmel A, Peshwe K, De Havenon A, Gilmore E, Matouk C, Sansing L, Schindler J, Sheth K, Petersen N. Abstract TMP89: Impaired Cerebral Autoregulation Increases Risk of Worse Outcome After Endovascular Thrombectomy in Stroke Patients With High Blood Pressure Variability Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tmp89.
  • Abstract TP11: CTA Collateral Status and Final Infarct Distribution Following Thrombectomy in Stroke Patients With Large Vessel OcclusionAl-Dasuqi K, Payabvash S, Abou Karam A, Strander S, Kodali S, Silverman A, Sansing L, Schindler J, Matouk C, Sheth K, Malhotra A, Petersen N. Abstract TP11: CTA Collateral Status and Final Infarct Distribution Following Thrombectomy in Stroke Patients With Large Vessel Occlusion Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tp11.
  • Abstract TP417: An Autoregulation-Derived Prediction Model for Midline Shift After Ischemic StrokeSilverman A, Wang A, Kodali S, Strander S, Kimmel A, Nguyen C, Peshwe K, Matouk C, Kimberly W, Sheth K, Tan C, Petersen N. Abstract TP417: An Autoregulation-Derived Prediction Model for Midline Shift After Ischemic Stroke Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tp417.
  • Abstract TP40: Time From Stroke Onset to Reperfusion is Associated With Worse Functional Outcomes in Patients With Rapidly Progressing InfarctsWang A, Strander S, Kodali S, Silverman A, Kimmel A, Nguyen C, Peshwe K, Sansing L, Schindler J, Matouk C, Sheth K, Petersen N. Abstract TP40: Time From Stroke Onset to Reperfusion is Associated With Worse Functional Outcomes in Patients With Rapidly Progressing Infarcts Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tp40.
  • Abstract WP374: High Frequency Blood Pressure Monitoring in the Acute Phase of Large Vessel Occlusion Ischemic StrokePeshwe K, Nguyen C, Kimmel A, Kodali S, Silverman A, Strander S, Wang A, Wira C, Sansing L, Matouk C, Sheth K, Petersen N. Abstract WP374: High Frequency Blood Pressure Monitoring in the Acute Phase of Large Vessel Occlusion Ischemic Stroke Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp374.
  • Abstract WP413: Portable, Bedside, Point of Care Magnetic Resonance Imaging in an Intensive Care Setting for Intracranial HemorrhageCahn B, Shah J, By S, Welch E, Sacolick L, Yuen M, Mazurek M, Wira C, Leasure A, Matouk C, Ward A, Payabvash S, Beekman R, Brown S, Falcone G, Gobeske K, Petersen N, Jasne A, Sharma R, Schindler J, Sansing L, Gilmore E, Sze G, Rosen M, Kimberly W, Sheth K. Abstract WP413: Portable, Bedside, Point of Care Magnetic Resonance Imaging in an Intensive Care Setting for Intracranial Hemorrhage Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp413.
  • Abstract TMP14: Contemporary Use of IV Alteplase in Acute Ischemic Stroke Beyond 4.5 Hours of Stroke Onset in Clinical Practice is RareSchwamm L, Xu H, Matsouaka R, Shah S, Sheth K, Saver J, Xian Y, Fonarow G, Smith E. Abstract TMP14: Contemporary Use of IV Alteplase in Acute Ischemic Stroke Beyond 4.5 Hours of Stroke Onset in Clinical Practice is Rare Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tmp14.
  • Abstract TMP49: Social Network Simulation Identifies Persistent Racial Disparities of Delay to Hospital in Acute Ischemic Stroke PatientsGreben R, Sheth K, Dhand A. Abstract TMP49: Social Network Simulation Identifies Persistent Racial Disparities of Delay to Hospital in Acute Ischemic Stroke Patients Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tmp49.
  • Abstract WMP97: Haptoglobin is Associated With Increased Early Perihematoma Edema Progression in Spontaneous Intracranial HemorrhageHalstead M, Mould W, Sheth K, Rosand J, Thompson R, Levy A, Hanley D, Goldstien J, Nyquist P. Abstract WMP97: Haptoglobin is Associated With Increased Early Perihematoma Edema Progression in Spontaneous Intracranial Hemorrhage Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wmp97.
  • Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic strokePowers W, Rabinstein A, Ackerson T, Adeoye O, Bambakidis N, Becker K, Biller J, Brown M, Demaerschalk B, Hoh B, Jauch E, Kidwell C, Leslie-Mazwi T, Ovbiagele B, Scott P, Sheth K, Southerl A, Summers D, Tirschwell. Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic stroke International Journal Of Cerebrovascular Diseases 2020, 28: 1-43. DOI: 10.3760/cma.j.issn.1673-4165.2020.01.001.
  • Percutaneous Trans-Carotid Puncture for Mechanical Thrombectomy in Acute Ischemic Stroke Patients is Safe and Effective: A Large, Single-Center Case SeriesCord B, Wang A, Chouairi F, Koo A, Porto C, Silverman A, Kodali S, Strander S, Falcone G, Sheth K, Hebert R, Sansing L, Schindler J, Petersen N, Matouk C. Percutaneous Trans-Carotid Puncture for Mechanical Thrombectomy in Acute Ischemic Stroke Patients is Safe and Effective: A Large, Single-Center Case Series Neurosurgery 2019, 66: 310-167. DOI: 10.1093/neuros/nyz310_167.
  • Deviation from Dynamic and Personalized Optimal Blood Pressure Targets is Associated With Worse Functional Outcomes After Aneurysmal Subarachnoid HemorrhageSilverman A, Kodali S, Strander S, Gilmore E, Kimmel A, Wang A, Cord B, Falcone G, Hebert R, Matouk C, Sheth K, Petersen N. Deviation from Dynamic and Personalized Optimal Blood Pressure Targets is Associated With Worse Functional Outcomes After Aneurysmal Subarachnoid Hemorrhage Neurosurgery 2019, 66: 310-186. DOI: 10.1093/neuros/nyz310_186.
  • Preliminary Experience With Proximal Flow Reversal During Intracranial Balloon Angioplasty and Stenting for Symptomatic, Severe Intracranial StenosisCord B, Cord B, Santarosa C, Santarosa C, Sujijantarat N, Kundishora A, Falcone G, Sheth K, Sansing L, Schindler J, Petersen N, Matouk C. Preliminary Experience With Proximal Flow Reversal During Intracranial Balloon Angioplasty and Stenting for Symptomatic, Severe Intracranial Stenosis Neurosurgery 2019, 66: 310-675. DOI: 10.1093/neuros/nyz310_675.
  • 1. The Pathophysiology of Intracranial Hypertension and Cerebral Herniation SyndromesSheth K, McCullough M. 1. The Pathophysiology of Intracranial Hypertension and Cerebral Herniation Syndromes 2019, 1-27. DOI: 10.36019/9780813579337-003.
  • Abstract 18: Genetically-Determined Cholesterol Levels are Associated with Risk of Spontaneous Intracerebral HemorrhageKirsch E, Leasure A, Matouk C, Sansing L, Crawford K, Kourkoulis C, Woo D, Rosand J, Anderson C, Sheth K, Falcone G. Abstract 18: Genetically-Determined Cholesterol Levels are Associated with Risk of Spontaneous Intracerebral Hemorrhage Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.18.
  • Abstract 76: Intensive Blood Pressure Reduction is Associated With Reduced Hematoma Expansion in Deep Intracerebral Hemorrhage: A Secondary Analysis of ATACH-2Leasure A, Qureshi A, Goldstein J, Murthy S, Kamel H, Woo D, Matouk C, Sansing L, Sheth K, Falcone G. Abstract 76: Intensive Blood Pressure Reduction is Associated With Reduced Hematoma Expansion in Deep Intracerebral Hemorrhage: A Secondary Analysis of ATACH-2 Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.76.
  • Abstract 77: Perihematomal Edema Expansion Rate is Associated With Poor Functional Outcomes in Basal Ganglia Intracerebral HemorrhageLeasure A, Qureshi A, Goldstein J, Murthy S, Kamel H, Woo D, Matouk C, Sansing L, Falcone G, Sheth K. Abstract 77: Perihematomal Edema Expansion Rate is Associated With Poor Functional Outcomes in Basal Ganglia Intracerebral Hemorrhage Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.77.
  • Abstract TP15: Percutaneous Transcarotid Puncture is a Viable Alternative for Thrombectomy in Acute Ischemic Stroke Patients With Difficult Vascular AccessWang A, Cord B, Chouairi F, Koo A, Porto C, Silverman A, Kodali S, Strander S, Hebert R, Falcone G, Sheth K, Sansing L, Schindler J, Matouk C, Petersen N. Abstract TP15: Percutaneous Transcarotid Puncture is a Viable Alternative for Thrombectomy in Acute Ischemic Stroke Patients With Difficult Vascular Access Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.tp15.
  • Abstract WMP97: Racial/Ethnic Disparities in the Risk of Intracerebral Hemorrhage RecurrenceKing Z, Leasure A, Torres-Lopez V, Woo D, Hanley D, Ziai W, Murthy S, Matouk C, Sansing L, Falcone G, Sheth K. Abstract WMP97: Racial/Ethnic Disparities in the Risk of Intracerebral Hemorrhage Recurrence Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.wmp97.
  • Abstract WP223: Ischemic and Hemorrhagic Stroke in Native AmericansKing Z, Beekman R, Chu S, Leasure A, Orgrass H, Gilmore E, Sansing L, Matouk C, Sheth K, Falcone G. Abstract WP223: Ischemic and Hemorrhagic Stroke in Native Americans Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.wp223.
  • Abstract 147: Individualized Blood Pressure Management After Subarachnoid Hemorrhage Using Real-time Autoregulation Monitoring: A Pilot Study Using NIRS and ICP-derived Limits of AutoregulationSilverman A, Wang A, Kodali S, Strander S, Cord B, Hebert R, Matouk C, Gilmore E, Sheth K, Petersen N. Abstract 147: Individualized Blood Pressure Management After Subarachnoid Hemorrhage Using Real-time Autoregulation Monitoring: A Pilot Study Using NIRS and ICP-derived Limits of Autoregulation Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.147.
  • Abstract 95: Exceeding Personalized Blood Pressure Targets After Endovascular Stroke Therapy is Associated With Hemorrhagic Transformation and Worse Functional OutcomePetersen N, Wang A, Strander S, Kodali S, Silverman A, Gilmore E, Sansing L, Schindler J, Hebert R, Cord B, Matouk C, Sheth K. Abstract 95: Exceeding Personalized Blood Pressure Targets After Endovascular Stroke Therapy is Associated With Hemorrhagic Transformation and Worse Functional Outcome Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.95.
  • Abstract TP34: Malignant CT Perfusion Profile is Associated With Increased Sensitivity to Blood Pressure Reductions During Endovascular Stroke TherapyStrander S, Wang A, Kodali S, Silverman A, Agarwal T, Stretz C, Zheng-Lin B, Lopez Cardenas G, Sansing L, Schindler J, Matouk C, Hebert R, Sheth K, Ortega Gutierrez S, Petersen N. Abstract TP34: Malignant CT Perfusion Profile is Associated With Increased Sensitivity to Blood Pressure Reductions During Endovascular Stroke Therapy Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.tp34.
  • Abstract WP3: Decreases in Blood Pressure During Endovascular Stroke Therapy are Associated With Larger Infarct Volumes and Poor Functional OutcomePetersen N, Wang A, Zhen-Li B, Strander S, Kodali S, Silverman A, Sansing L, Lopez G, Schindler J, Matouk C, Hebert R, Sheth K, Ortega Gutierrez S. Abstract WP3: Decreases in Blood Pressure During Endovascular Stroke Therapy are Associated With Larger Infarct Volumes and Poor Functional Outcome Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.wp3.
  • Abstract TP411: Distinct Systolic Blood Pressure Trajectories 72 Hours After Mechanical Thrombectomy Predict Hemorrhagic Transformation and Poor Functional OutcomeKodali S, Wang A, Strander S, Silverman A, Agarwal T, Stretz C, Sansing L, Schindler J, Sheth K, Petersen N. Abstract TP411: Distinct Systolic Blood Pressure Trajectories 72 Hours After Mechanical Thrombectomy Predict Hemorrhagic Transformation and Poor Functional Outcome Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.tp411.
  • Abstract 29: Low Socioeconomic Status and Longer Home-to-Hospital Distances Are Associated With Less Timely Treatment of Ischemic StrokeAder J, Wu J, Fonarow G, Smith E, Shah S, Xian Y, Bhatt D, Schwamm L, Reeves M, Matsouaka R, Sheth K. Abstract 29: Low Socioeconomic Status and Longer Home-to-Hospital Distances Are Associated With Less Timely Treatment of Ischemic Stroke Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.29.
  • Abstract 75: Predictors of Poor Outcome After Intracerebral Hemorrhage: Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) StudyWoo D, Comeau M, Venema S, Anderson C, Flaherty M, Testai F, Kittner S, Frankel M, James M, Sung G, Elkind M, Worrall B, Kidwell C, Gonzales N, Koch S, Hall C, Birnbaum L, Mayson D, Coull B, Malkoff M, Sheth K, Chong J, McCauley J, Osborne J, Wethington M, Gilkerson L, Behymer T, Coleman E, Sekar P, Moomaw C, Rosand J, Langefeld C. Abstract 75: Predictors of Poor Outcome After Intracerebral Hemorrhage: Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) Study Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.75.
  • Abstract TMP18: Intravenous Glibenclamide Reduces Hypoxanthine, a Novel Predictor of Brain Edema Formation: An Exploratory Analysis of GAMES-RPIrvine H, Acharjee A, Wolcott Z, Ament Z, Hinson H, Molyneaux B, Simard J, Sheth K, Kimberly W. Abstract TMP18: Intravenous Glibenclamide Reduces Hypoxanthine, a Novel Predictor of Brain Edema Formation: An Exploratory Analysis of GAMES-RP Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.tmp18.
  • Abstract TP400: Intravenous Glibenclamide Reduces Water Uptake and Mass Effect in Large Hemispheric Infarction (GAMES-RP Study)Vorasayan P, Vorasayan P, Bevers M, Bevers M, Beslow L, Beslow L, Sze G, Molyneaux B, Molyneaux B, Hinson H, Hinson H, Simard J, Simard J, Kummer R, Kummer R, Sheth K, Kimberly W, Kimberly W. Abstract TP400: Intravenous Glibenclamide Reduces Water Uptake and Mass Effect in Large Hemispheric Infarction (GAMES-RP Study) Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.tp400.
  • Abstract TP418: Asymptomatic Hemorrhagic Infarction on 24-Hour CT Post Intravenous Recombinant Tissue Plasminogen Activator for Acute Ischemic Stroke Predicts Symptomatic Intracerebral Hemorrhage After Initiation of Antiplatelet TherapyRicci B, Mac Grory B, Chang A, Cutting S, Burton T, Dakay K, McTaggart R, Jayaraman M, Reznik M, Thompson B, Wendell L, Mahta A, Rao S, Potter S, Sheth K, Willey J, Khatri P, Furie K, Yaghi S. Abstract TP418: Asymptomatic Hemorrhagic Infarction on 24-Hour CT Post Intravenous Recombinant Tissue Plasminogen Activator for Acute Ischemic Stroke Predicts Symptomatic Intracerebral Hemorrhage After Initiation of Antiplatelet Therapy Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.tp418.
  • Abstract TP98: Diabetes Mellitus Predicts Symptomatic Intracerebral Hemorrhage Following Thrombectomy in Acute Ischemic StrokeMontalvo M, Yakhind A, Jayaraman M, McTaggart R, Chang A, Akiki R, Mac Grory B, Cutting S, Burton T, Reznik M, Thompson B, Wendell L, Rao S, Potter S, Sheth K, Willey J, Furie K, Khatri P, Yaghi S. Abstract TP98: Diabetes Mellitus Predicts Symptomatic Intracerebral Hemorrhage Following Thrombectomy in Acute Ischemic Stroke Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.tp98.
  • Abstract WMP100: Prior Antiplatelet Use and Outcomes After Lobar, Deep, and Intraventricular HemorrhageMurthy S, Roh D, Chatterjee A, Chen M, Dlugash R, McBee N, ElJalby M, Merkler A, Navi B, Awad I, Hanley D, Sheth K, Kamel H, Ziai W. Abstract WMP100: Prior Antiplatelet Use and Outcomes After Lobar, Deep, and Intraventricular Hemorrhage Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.wmp100.
  • Abstract WMP98: Apolipoprotein E Genotype Predicts Anticoagulation-associated Intracerebral Hemorrhage RecurrenceUrday S, Biffi A, Rodriguez-Torres A, Pasi M, Kourkoulis C, Schwab K, Greenberg S, Viswanathan A, Gurol M, Sheth K, Anderson C, Rosand J. Abstract WMP98: Apolipoprotein E Genotype Predicts Anticoagulation-associated Intracerebral Hemorrhage Recurrence Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.wmp98.
  • 57 Improving the Safety and Quality of Inter-Hospital Transfer for Nontraumatic Intracerebral and Subarachnoid HemorrhageLittauer R, Sather J, Rothenberg C, Finn E, Yip M, Matouk C, Pham L, Sheth K, Ulrich A, Parwani Y, Venkatesh A. 57 Improving the Safety and Quality of Inter-Hospital Transfer for Nontraumatic Intracerebral and Subarachnoid Hemorrhage Annals Of Emergency Medicine 2018, 72: s25-s26. DOI: 10.1016/j.annemergmed.2018.08.062.
  • 105 Decreases in Blood Pressure During Endovascular Stroke Therapy Are Common and Associated With Poor Functional OutcomeMampre D, Wang A, Sheth K, Tan C, Hebert R, Matouk C, Petersen N. 105 Decreases in Blood Pressure During Endovascular Stroke Therapy Are Common and Associated With Poor Functional Outcome Neurosurgery 2018, 65: 82. DOI: 10.1093/neuros/nyy303.105.
  • History of Intracranial Hemorrhage Is Associated with In-Hospital Mortality in Ischemic Stroke Patients Treated with Intravenous ThrombolyticsSommaruga S, Chu S, Hwang D, Dearborn J, Sansing L, Cord B, Santarosa C, Samarth G, Petersen N, Gilmore E, Schindler J, Bijlenga P, Schaller K, Matouk C, Sheth K, Falcone G. History of Intracranial Hemorrhage Is Associated with In-Hospital Mortality in Ischemic Stroke Patients Treated with Intravenous Thrombolytics Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660745.
  • Spontaneous Intracerebral Hemorrhage in the Elderly PopulationSommaruga S, Beekman R, Chu S, King Z, Matouk C, Hwang D, Sheth K, Falcone G. Spontaneous Intracerebral Hemorrhage in the Elderly Population Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660768.
  • Predictors of Vessel Wall Enhancement in Unruptured Intracranial AneurysmsSommaruga S, Cord B, Santarosa C, Malhotra A, Jonhson M, Sheth K, Gunel M, Herbert R, Bijlenga P, Schaller K, Falcone G, Matouk C. Predictors of Vessel Wall Enhancement in Unruptured Intracranial Aneurysms Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660769.
  • 2018 Guidelines for the early management of patients with acute ischemic strokePowers W, Rabinstein A, Ackerson T, Adeoye O, Bambakidis N, Becker K, Biller J, Brown M, Demaerschalk B, Hoh B, Jauch E, Kidwell C, Leslie-Mazwi T, Ovbiagele B, Scott P, Sheth K, Southerland A, Summers D, Tirschwell D. 2018 Guidelines for the early management of patients with acute ischemic stroke International Journal Of Cerebrovascular Diseases 2018, 26: 81-113. DOI: 10.3760/cma.j.issn.1673-4165.2018.02.001.
  • Abstract WP203: Left Atrial Appendage Morphology is Similar in Embolic Stroke of Undetermined Source and Cardioembolic Stroke and Different From Atherothrombotic SubtypesYaghi S, Chang A, Hung P, Mac Grory B, Collins S, Gupta A, Reynolds J, Finn C, Hemendinger M, Cutting S, McTaggart R, Jayaraman M, Leasure A, Sansing L, Panda N, Song C, Chu A, Merkler A, Gialdini G, Sheth K, Kamel H, Elkind M, Greer D, Furie K, Atalay M. Abstract WP203: Left Atrial Appendage Morphology is Similar in Embolic Stroke of Undetermined Source and Cardioembolic Stroke and Different From Atherothrombotic Subtypes Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.wp203.
  • Abstract TMP14: Thrombolysis in Ischemic Stroke Patients with Prior History of Intracranial HemorrhageChu S, Sommaruga S, Hwang D, Dearborn J, Sansing L, Matouk C, Samarth G, Petersen N, Gilmore E, Schindler J, Sheth K, Falcone G. Abstract TMP14: Thrombolysis in Ischemic Stroke Patients with Prior History of Intracranial Hemorrhage Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.tmp14.
  • Abstract TP277: The Neurointensivists’ Role in Management of Cerebral Venous Sinus ThrombosisStretz C, Ghoshal S, Marcolini E, Hwang D, Petersen N, Schindler J, Sheth K, Falcone G, Gilmore E. Abstract TP277: The Neurointensivists’ Role in Management of Cerebral Venous Sinus Thrombosis Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.tp277.
  • Abstract TP304: Stroke-Specific Quality of Life as an Independent Outcome in Intracerebral HemorrhageLeasure A, Sreekrishnan A, Ormseth C, Miyares L, Mampre D, McLaughlin C, Amin H, Sansing L, Falcone G, Sheth K. Abstract TP304: Stroke-Specific Quality of Life as an Independent Outcome in Intracerebral Hemorrhage Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.tp304.
  • Abstract TP331: Plasma IL-6 Levels are Independently Associated With Functional Outcome and Markers of Secondary Injury in Spontaneous Intracerebral HemorrhageLeasure A, Steinschneider A, Falcone G, Gilmore E, Sansing L, Sheth K. Abstract TP331: Plasma IL-6 Levels are Independently Associated With Functional Outcome and Markers of Secondary Injury in Spontaneous Intracerebral Hemorrhage Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.tp331.
  • Abstract WMP101: Soluble St2 Predicts Functional Outcome After Spontaneous Intraparenchymal HemorrhageBevers M, Wolcott Z, Leasure A, Falcone G, Sansing L, Sheth K, Kimberly W. Abstract WMP101: Soluble St2 Predicts Functional Outcome After Spontaneous Intraparenchymal Hemorrhage Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.wmp101.
  • Abstract WMP31: Vessel Wall Enhancement is Associated With Clinical and Imaging Markers of Aneurysm InstabilitySommaruga S, Cord B, Molhotra A, Johnson M, Minja F, Gunel M, Sheth K, Herbert R, Melnikov F, Schaller K, Mandell D, Bijlenga P, Falcone G, Matouk C. Abstract WMP31: Vessel Wall Enhancement is Associated With Clinical and Imaging Markers of Aneurysm Instability Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.wmp31.
  • Abstract WMP96: Racial Variation in Comfort Measures Only Status in Patients With Intracerebral HemorrhageOrmseth C, Falcone G, Jasak S, Mampre D, Leasure A, Miyares L, Hwang D, James M, Testai F, Becker K, Tirschwell D, Langefeld C, Woo D, Sheth K. Abstract WMP96: Racial Variation in Comfort Measures Only Status in Patients With Intracerebral Hemorrhage Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.wmp96.
  • Abstract WP320: Blood Pressure Reduction During Endovascular Stroke Therapy is Associated With Poor Functional OutcomeWang A, Mampre D, Sheth K, Tan C, Matouk C, Hebert R, Petersen N. Abstract WP320: Blood Pressure Reduction During Endovascular Stroke Therapy is Associated With Poor Functional Outcome Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.wp320.
  • Abstract 35: Hyperexcitability and Seizures in Primary Intraventricular HemorrhageStretz C, Sheikh Z, Maciel C, Sheth K, Hirsch L, Gilmore E. Abstract 35: Hyperexcitability and Seizures in Primary Intraventricular Hemorrhage Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.35.
  • Abstract 130: Intracerebral Hemorrhage and Subsequent Risk of Arterial ThromboembolismMurthy S, Diaz I, Merkler A, Iadecola C, Navi B, Sheth K, Kamel H. Abstract 130: Intracerebral Hemorrhage and Subsequent Risk of Arterial Thromboembolism Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.130.
  • Abstract 132: Utility of Prophylactic Antiepileptic Drug Administration on Seizure Prevention and Disability Following Intracerebral Hemorrhage in the Ethnic/Racial Variations of Intracerebral Hemorrhage StudySavalia K, Sekar P, Moomaw C, Koch S, Sheth K, Woo D, Mayson D. Abstract 132: Utility of Prophylactic Antiepileptic Drug Administration on Seizure Prevention and Disability Following Intracerebral Hemorrhage in the Ethnic/Racial Variations of Intracerebral Hemorrhage Study Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.132.
  • Abstract 51: Organ- and Cell-Specific Immune Responses Are Associated With the Outcomes of Intracerebral HemorrhageShi K, Zhang J, Li Z, li M, Han Y, Wang L, Zhang Z, Yu C, Zhang F, Song L, Dong J, Liu Q, La Cava A, Sheth K, Shi F. Abstract 51: Organ- and Cell-Specific Immune Responses Are Associated With the Outcomes of Intracerebral Hemorrhage Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.51.
  • Abstract TP196: Incidence of Atrial Fibrillation in Patients With Recent Ischemic Stroke versus Matched ControlsKamel H, Witsch J, Merkler A, Sheth K, Navi B. Abstract TP196: Incidence of Atrial Fibrillation in Patients With Recent Ischemic Stroke versus Matched Controls Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.tp196.
  • Abstract TP43: Trends in Interhospital Transfers and Mechanical Thrombectomy for Acute Ischemic StrokeGeorge B, Pieters T, Zammit C, Sheth K, Bhalla T. Abstract TP43: Trends in Interhospital Transfers and Mechanical Thrombectomy for Acute Ischemic Stroke Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.tp43.
  • Abstract WMP2: Outcomes of Endovascular Therapy Following Interhospital TransferShah S, Sheng S, Xian Y, Zachrison K, Sheth K, Saver J, Smith E, Fonarow G, Schwamm L. Abstract WMP2: Outcomes of Endovascular Therapy Following Interhospital Transfer Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.wmp2.
  • Abstract WP292: Changing Landscape of Stroke Systems of Care: Increase in Inter Hospital Transfer in the United StatesShah S, Sheng S, Xian Y, Zachrison K, Sheth K, Saver J, Smith E, Fonarow G, Schwamm L. Abstract WP292: Changing Landscape of Stroke Systems of Care: Increase in Inter Hospital Transfer in the United States Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.wp292.
  • Abstract WP347: Cardioembolic Risk and Recovery After Anticoagulation-Related Intracerebral HemorrhageBiffi A, Murphy M, Kuramatsu J, Leasure A, Kamel H, Kourkoulis C, Schwab K, Ayres A, Elm J, Gurol M, Greenberg S, Viswanathan A, Anderson C, Schwab S, Rosand J, Testai F, Woo D, Huttner H, Sheth K. Abstract WP347: Cardioembolic Risk and Recovery After Anticoagulation-Related Intracerebral Hemorrhage Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.wp347.
  • Abstract WP5: Reperfusion Reduces Brain Edema in Patients With Acute Ischemic Stroke. A MR CLEAN SubstudyKimberly W, Dutra B, Boers A, Alves H, Berkhemer O, van den Berg L, Sheth K, Roos Y, van der Lugt A, Beenen L, Dippel D, van Zwam W, van Oostenbrugge R, Lingsma H, Marquering H, Majoie C. Abstract WP5: Reperfusion Reduces Brain Edema in Patients With Acute Ischemic Stroke. A MR CLEAN Substudy Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.wp5.
  • 49 Management of Postoperative SeizuresGrory B, Hirsch L, Gilmore E, Sheth K. 49 Management of Postoperative Seizures 2018, 497-507. DOI: 10.1016/b978-0-323-32106-8.00049-2.
  • 295 Interhospital Transfer is Not a Predictor of In-Hospital Mortality for Patients With Nontraumatic Intracranial HemorrhageYip M, Sather J, Sheth K, Matouk C, Littauer R, Finn E, Rothenberg C, Costello D, Parwani V, Venkatesh A. 295 Interhospital Transfer is Not a Predictor of In-Hospital Mortality for Patients With Nontraumatic Intracranial Hemorrhage Annals Of Emergency Medicine 2017, 70: s116-s117. DOI: 10.1016/j.annemergmed.2017.07.273.
  • 168 Wall Enhancement in Unruptured Aneurysms is Associated with Symptomatic Presentation and SizeCord B, Sommaruga S, Hebert R, Malhotra A, Johnson M, Minja F, Gunel M, Sheth K, Falcone G, Matouk C. 168 Wall Enhancement in Unruptured Aneurysms is Associated with Symptomatic Presentation and Size Neurosurgery 2017, 64: 243. DOI: 10.1093/neuros/nyx417.168.
  • The Role of Advanced Practice Clinicians in the Neuroscience ICUWhite J, Sheth K. The Role of Advanced Practice Clinicians in the Neuroscience ICU 2017, 1-4. DOI: 10.1007/978-3-319-48669-7_1.
  • Intracerebral HemorrhageStevenson D, Sheth K. Intracerebral Hemorrhage 2017, 75-91. DOI: 10.1007/978-3-319-48669-7_5.
  • Abstract TP338: Differences Between the Modified Rankin Scale and Barthel Index in Measuring Intracerebral Hemorrhage Recovery at 12 MonthsSreekrishnan A, Leasure A, Zhou S, Amin H, Petersen N, Hwang D, Schindler J, Gilmore E, Sansing L, Greer D, Sheth K. Abstract TP338: Differences Between the Modified Rankin Scale and Barthel Index in Measuring Intracerebral Hemorrhage Recovery at 12 Months Stroke 2017, 48 DOI: 10.1161/str.48.suppl_1.tp338.
  • Abstract 15: Long Term Outcomes of Intravenous Glyburide in Patients 70 Years of Age or Under: Subgroup Analysis From the Phase II GAMES-RP Study of Patients with Large Hemispheric InfarctionSheth K, Cheung K, Cheung K, Elm J, Elm J, Hinson H, Molyneaux B, Molyneaux B, Beslow L, Beslow L, Sze G, Ostwaldt A, Ostwaldt A, Kimberly W, Kimberly W. Abstract 15: Long Term Outcomes of Intravenous Glyburide in Patients 70 Years of Age or Under: Subgroup Analysis From the Phase II GAMES-RP Study of Patients with Large Hemispheric Infarction Stroke 2017, 48 DOI: 10.1161/str.48.suppl_1.15.
  • Abstract TMP24: Analysis of Adjudicated Edema Endpoints in the Glyburide Advantage in Malignant Edema and Stroke (GAMES-RP) TrialKimberly W, von Kummer R, Demchuk A, Romero J, Elm J, Hinson H, Molyneaux B, Sheth K. Abstract TMP24: Analysis of Adjudicated Edema Endpoints in the Glyburide Advantage in Malignant Edema and Stroke (GAMES-RP) Trial Stroke 2017, 48 DOI: 10.1161/str.48.suppl_1.tmp24.
  • Abstract TMP54: Seasonal Patterns of Ischemic Stroke in the United StatesChu S, Cox M, Fonarow G, Smith E, Schwamm L, Bhatt D, Xian Y, Matsouaka R, Sheth K. Abstract TMP54: Seasonal Patterns of Ischemic Stroke in the United States Stroke 2017, 48 DOI: 10.1161/str.48.suppl_1.tmp54.
  • Abstract TP196: Incident Atrial Fibrillation After Ischemic versus Hemorrhagic StrokeWitsch J, Merkler A, Gialdini G, Navi B, Sheth K, Kamel H. Abstract TP196: Incident Atrial Fibrillation After Ischemic versus Hemorrhagic Stroke Stroke 2017, 48 DOI: 10.1161/str.48.suppl_1.tp196.
  • Abstract TP343: The 1-1 Haptoglobin Phenotype is Associated With Perihematoma Edema Progression in Acute Intracranial HemorrhageHalstead M, Mould W, Sheth K, Rosand J, Thompson R, Levy A, Hanley D, Goldstein J, Nyquist P. Abstract TP343: The 1-1 Haptoglobin Phenotype is Associated With Perihematoma Edema Progression in Acute Intracranial Hemorrhage Stroke 2017, 48 DOI: 10.1161/str.48.suppl_1.tp343.
  • Abstract WP47: Reperfusion Following Ischemic Stroke is Associated with Reduced Brain EdemaIrvine H, Battey T, Ostwaldt A, Campbell B, Davis S, Donnan G, Sheth K, Kimberly W. Abstract WP47: Reperfusion Following Ischemic Stroke is Associated with Reduced Brain Edema Stroke 2017, 48 DOI: 10.1161/str.48.suppl_1.wp47.
  • Chapter 10 Sur1–Trpm4-Promising Target for Brain Edema Treatment in Brain Edema From Molecular Mechanisms to Clinical PracticeUrday S, Sheth K, Simard J. Chapter 10 Sur1–Trpm4-Promising Target for Brain Edema Treatment in Brain Edema From Molecular Mechanisms to Clinical Practice 2017, 183-198. DOI: 10.1016/b978-0-12-803196-4.00010-2.
  • Abstract WP292: Discharge Disposition After Intracerebral Hemorrhage and Functional OutcomesOsborne J, Sekar P, Moomaw C, Hwang D, Sheth K, Langefeld C, Vashkevich A, Woo D. Abstract WP292: Discharge Disposition After Intracerebral Hemorrhage and Functional Outcomes Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.wp292.
  • Abstract WMP86: Evaluation of Cerebrospinal Fluid Dynamics and External Ventricular Drain Management in the Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage trial (CLEAR III)Ziai W, Bhuiyan M, McBee N, Dlugash R, Sheth K, Ram M, Mayo S, Thompson C, Lane K, Awad I, Hanley D. Abstract WMP86: Evaluation of Cerebrospinal Fluid Dynamics and External Ventricular Drain Management in the Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage trial (CLEAR III) Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.wmp86.
  • Abstract 211: Do Women Receive Less Aggressive Care Following Intracerebral Hemorrhage?Chaturvedi S, Koch S, Sekar P, Moomaw C, Osborne J, Boehme A, Demel S, Li J, Woodrich E, Bracho J, James M, Sheth K, Cai X, Langefeld C, Woo D. Abstract 211: Do Women Receive Less Aggressive Care Following Intracerebral Hemorrhage? Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.211.
  • Abstract WMP88: Perihematomal Edema Expansion Rate Predicts Functional Outcome in Deep Intracerebral HemorrhageGrunwald Z, Urday S, Beslow L, Vashkevich A, Ayres A, Greenberg S, Goldstein J, Battey T, Simard J, Rosand J, Kimberly W, Sheth K. Abstract WMP88: Perihematomal Edema Expansion Rate Predicts Functional Outcome in Deep Intracerebral Hemorrhage Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.wmp88.
  • Abstract WP357: The Impact of Specific Neuroanatomical Location in Deep Supratentorial Intracerebral Hemorrhage (ICH): Findings From the Ethnic/Racial Variations of ICH StudySheth K, Moomaw C, Osborne J, Martini S, Katz B, Charidimou A, Comeau M, Langefeld C, Vashkevich A, Woo D. Abstract WP357: The Impact of Specific Neuroanatomical Location in Deep Supratentorial Intracerebral Hemorrhage (ICH): Findings From the Ethnic/Racial Variations of ICH Study Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.wp357.
  • Abstract WP368: Atrial Fibrillation in Patients With Intracerebral Hemorrhage - Proportion of Patients With Indications for AnticoagulationTirschwell D, Sheth K, Leira E, Kamel H, Greenberg S, Rosand J. Abstract WP368: Atrial Fibrillation in Patients With Intracerebral Hemorrhage - Proportion of Patients With Indications for Anticoagulation Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.wp368.
  • Abstract W P126: Accurate Outcome Predictions for Intracerebral Hemorrhage Patients Are More Likely Than Inaccurate Predictions to Be Influenced by Co-morbidities Not Included in Clinical ScalesHwang D, Dell C, Sparks M, Watson T, Langefeld C, Comeau M, Rosand J, Battey T, Koch S, Perez M, James M, McFarlin J, Osborne J, Woo D, Kittner S, Sheth K. Abstract W P126: Accurate Outcome Predictions for Intracerebral Hemorrhage Patients Are More Likely Than Inaccurate Predictions to Be Influenced by Co-morbidities Not Included in Clinical Scales Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.wp126.
  • Abstract NS20: Discharge Disposition After Intracerebral HemorrhageOsborne J, Langefeld C, Moomaw C, Sheth K, Hwang D, Flaherty M, Vashkevich A, Gohs J, Woo D. Abstract NS20: Discharge Disposition After Intracerebral Hemorrhage Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.ns20.
  • Abstract T MP65: Rate of Peri-Hematomal Edema Expansion Predicts Outcome After Intracerebral HemorrhageUrday S, Beslow L, Goldstein D, Dai F, Zhang F, Vashkevich A, Ayres A, Battey T, Simard M, Rosand J, Kimberly T, Sheth K. Abstract T MP65: Rate of Peri-Hematomal Edema Expansion Predicts Outcome After Intracerebral Hemorrhage Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.tmp65.
  • Abstract T MP68: Validating the Association of Peripheral Monocyte Count with 30-Day Case-Fatality in Intracerebral HemorrhageWalsh K, Sekar P, Langefeld C, Moomaw C, Elkind M, James M, Osborne J, Sheth K, Woo D, Adeoye O. Abstract T MP68: Validating the Association of Peripheral Monocyte Count with 30-Day Case-Fatality in Intracerebral Hemorrhage Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.tmp68.
  • Abstract T MP92: Variation of Blood Pressure Response of Antihypertensive Agents in Acute Intracerebral Hemorrhage (ICH)Lin W, Langefeld C, Koch S, Moomaw C, Chan Y, Sheth K, Sekar P, Osborne J, Woo D. Abstract T MP92: Variation of Blood Pressure Response of Antihypertensive Agents in Acute Intracerebral Hemorrhage (ICH) Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.tmp92.
  • Abstract 85: The Important Role of Drip and Ship Administration in Expanded Use of Thrombolytic Therapy in the United StatesSheth K, Smith E, Grau-Sepulveda M, Kleindorfer D, Fonarow G, Schwamm L. Abstract 85: The Important Role of Drip and Ship Administration in Expanded Use of Thrombolytic Therapy in the United States Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.85.
  • Abstract T P48: Neuroimaging Markers of Swelling Predict Outcome After Acute Ischemic StrokeBattey T, Karki M, Singhal A, Wu O, Sadaghiani S, Campbell B, Davis S, Donnan G, Sheth K, Kimberly W. Abstract T P48: Neuroimaging Markers of Swelling Predict Outcome After Acute Ischemic Stroke Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.tp48.
  • Abstract W P266: The Discharge Modified Rankin Score Correlates with Established Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated with ThrombolysisAsuzu D, Nystrom K, Sheth K, Halliday J, Wira C, Greer D, Pritchard D, Schindler J. Abstract W P266: The Discharge Modified Rankin Score Correlates with Established Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated with Thrombolysis Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.wp266.
  • Abstract W P265: Improved Symptomatic ICH Rates for Ischemic Stroke Patients Receiving IV rtPANystrom K, Asuzu D, Sheth K, Chi N, Halliday J, Wira C, Greer D, Schindler J. Abstract W P265: Improved Symptomatic ICH Rates for Ischemic Stroke Patients Receiving IV rtPA Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.wp265.
  • Abstract W P64: DRAGON Score Outperforms 7 Other Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated With IV r-tPAAsuzu D, Nystrom K, Chi N, Greer D, Halliday J, Wira C, Sschindler J, Sheth K. Abstract W P64: DRAGON Score Outperforms 7 Other Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated With IV r-tPA Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.wp64.
  • Abstract 211: Subjective Judgments of Physicians and Nurses Are More Accurate Than Formal Clinical Scales in Predicting Functional Outcome After Intracerebral HemorrhageHwang D, Dell C, Sparks M, Watson T, Langefeld C, Comeau M, Rosand J, Battey T, Koch S, Perez M, James M, McFarlin J, Osborne J, Woo D, Kittner S, Sheth K. Abstract 211: Subjective Judgments of Physicians and Nurses Are More Accurate Than Formal Clinical Scales in Predicting Functional Outcome After Intracerebral Hemorrhage Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.211.
  • Abstract 179: Racial-ethnic Blood Pressure Differences in Acute Intracerebral Hemorrhage.Koch S, Elkind M, Testai F, Brown M, Martini S, Sheth K, Chong J, Osborne J, Moomaw C, Langefeld C, Woo D. Abstract 179: Racial-ethnic Blood Pressure Differences in Acute Intracerebral Hemorrhage. Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.179.
  • Abstract T MP91: Association of Gender-Age Interaction With Outcome After Intracerebral Hemorrhage in Multiple EthnicitiesJames M, Sekar P, Langfeld C, Moomaw C, Worrall B, Sheth K, Frankel M, Martin S, Osborne J, Woo D. Abstract T MP91: Association of Gender-Age Interaction With Outcome After Intracerebral Hemorrhage in Multiple Ethnicities Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.tmp91.
  • Abstract T P28: Brain MRI FLAIR Signal Intensity Ratio Is Correlated With Matrix Metalloproteinase-9 Level In Acute Ischemic StrokeJha R, Battey T, Pham L, Irvine H, Furie K, Sheth K, Kimberly W. Abstract T P28: Brain MRI FLAIR Signal Intensity Ratio Is Correlated With Matrix Metalloproteinase-9 Level In Acute Ischemic Stroke Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.tp28.
  • Abstract T P340: Delays in Seeking Medical Attention in Intracerebral HemorrhageTestai F, Langefeld C, Mukarram F, Castillo N, Hillmann M, Sheth K, Smith S, Ali L, Rinek G, Moomaw C, Osborne J, Woo D. Abstract T P340: Delays in Seeking Medical Attention in Intracerebral Hemorrhage Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.tp340.
  • Abstract W P259: ICH &FUNC Scores in the Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) StudySheth K, Sung G, Langefeld C, Moomaw C, Osborne J, Elkind M, Martini S, Vashkevich A, Koch S, Rosand J, Woo D. Abstract W P259: ICH &FUNC Scores in the Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) Study Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.wp259.
  • Abstract W MP16: Lower Apparent Diffusion Coefficient Ratio Predicts Increased Swelling After Ischemic StrokeBattey T, Karki M, Wu O, Singhal A, Sheth K, Kimberly W. Abstract W MP16: Lower Apparent Diffusion Coefficient Ratio Predicts Increased Swelling After Ischemic Stroke Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.wmp16.
  • Abstract W P235: Predictors of Platelet Transfusion in Patients with Intracerebral HemorrhageGuerrero W, Gonzales N, Sekar P, Castillo J, Moomaw C, Worrall B, Langefeld C, Martini S, Flaherty M, Sheth K, Osborne J, Woo D. Abstract W P235: Predictors of Platelet Transfusion in Patients with Intracerebral Hemorrhage Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.wp235.
  • Abstract 164: Outcome Prediction After Endovascular Reperfusion Therapy For Acute Ischemic Stroke: The SNARL ScorePrabhakaran S, Sheth K, Terry J, Nogueira R, Horev A, Nguyen T, Gandhi D, Wisco D, Glenn B, Tayal A, Ludwig B, Hussain M, Jovin T, Clemmons P, Cronin C, Tian M, Gupta R. Abstract 164: Outcome Prediction After Endovascular Reperfusion Therapy For Acute Ischemic Stroke: The SNARL Score Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.a164.
  • Abstract 49: Withdrawal of Care in the Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) StudySheth K, Martini S, Tirschwell D, Becker K, Worrall B, James M, Sung G, Brown M, Langefeld C, Osborne J, Moomaw C, Woo D. Abstract 49: Withdrawal of Care in the Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) Study Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.a49.
  • Abstract TMP22: Intravenous Glyburide Treatment is Associated with Reduced Matrix Metalloproteinase-9 in Human Acute StrokePham L, O’Connor S, Yarbrough K, Jacobson S, Stern B, Sheth K, Kimberly W. Abstract TMP22: Intravenous Glyburide Treatment is Associated with Reduced Matrix Metalloproteinase-9 in Human Acute Stroke Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.atmp22.
  • Abstract TP188: Location of Intracerebral Hemorrhage in a Tri-ethnic Cohort: The ERICH StudyBirnbaum L, Leonard A, Andino J, Moomaw C, Langfeld C, Brown W, Osborne J, Martini S, Testai F, Sheth K, Woo D. Abstract TP188: Location of Intracerebral Hemorrhage in a Tri-ethnic Cohort: The ERICH Study Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.atp188.
  • Abstract TP8: Safety And Outcome After Endovascular Reperfusion Therapy In Elderly Patients With Acute Ischemic StrokePrabhakaran S, Sheth K, Terry J, Nogueira R, Horev A, Nguyen T, Gandhi D, Wisco D, Glenn B, Tayal A, Ludwig B, Hussain M, Jovin T, Clemmons P, Cronin C, Tian M, Gupta R. Abstract TP8: Safety And Outcome After Endovascular Reperfusion Therapy In Elderly Patients With Acute Ischemic Stroke Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.atp8.
  • Abstract WP140: Concurrent Anterior Cerebral Artery Involvement Is Predictive of Mortality In Severe Middle Cerebral Artery Ischemic StrokeWalcott B, Miller J, Kwon C, Sheth S, Hiller M, Cronin C, Schwamm L, Simard J, Kimberly W, Sheth K. Abstract WP140: Concurrent Anterior Cerebral Artery Involvement Is Predictive of Mortality In Severe Middle Cerebral Artery Ischemic Stroke Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.awp140.
  • Abstract 102: Adherence to ECASS III 3-4.5 Hour Exclusion Criteria and Association with Outcome in Clinical Practice: Data from Get With The Guidelines (GWTG)-StrokeCronin C, Sheth K, Zhao X, Messe S, Olson D, Hernandez A, Bhatt D, Schwamm L, Smith E. Abstract 102: Adherence to ECASS III 3-4.5 Hour Exclusion Criteria and Association with Outcome in Clinical Practice: Data from Get With The Guidelines (GWTG)-Stroke Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.a102.
  • Abstract 211: GAMES (Glyburide Advantage in Malignant Edema and Stroke) Pilot StudySheth K, Kimberly W, Elm J, Yarbrough K, O'Connor S, Hammer M, Kane A, Busl K, Cole T, Yoo A, Jacobson S, Stern B. Abstract 211: GAMES (Glyburide Advantage in Malignant Edema and Stroke) Pilot Study Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.a211.
  • Abstract TP290: Glyburide Reduces Cytotoxic Edema within the Cerebral Peduncles in Acute Ischemic StrokeEdlow B, Wu O, Singhal A, Chaudhry Z, Yoo A, Stern B, Sheth K, Kimberly W. Abstract TP290: Glyburide Reduces Cytotoxic Edema within the Cerebral Peduncles in Acute Ischemic Stroke Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.atp290.
  • Abstract TP37: Prediction of Outcome in Cerebellar Infarction by Diffusion MRITchopev Z, Hiller M, Betz J, Zhuo J, Gullapalli R, Sheth K. Abstract TP37: Prediction of Outcome in Cerebellar Infarction by Diffusion MRI Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.atp37.
  • Traditional systolic blood pressure targets underestimate hypotension-induced secondary brain injuryBrenner M, Stein D, Hu P, Aarabi B, Sheth K, Scalea T. Traditional systolic blood pressure targets underestimate hypotension-induced secondary brain injury Journal Of Trauma And Acute Care Surgery 2012, 72: 1456-1457. DOI: 10.1097/01.ta.0000414833.80358.72.
  • Penetrating Traumatic Brain Injury: A 10-Year Experience (P06.265)Park H, Stein D, Kufera J, Aarabi B, Scalea T, Sheth K. Penetrating Traumatic Brain Injury: A 10-Year Experience (P06.265) Neurology 2012, 78: p06.265-p06.265. DOI: 10.1212/wnl.78.1_meetingabstracts.p06.265.
  • Mortality and Penetrating Traumatic Brain Injury: Analysis of a 10 Year Cohort (P06.267)Park H, Stein D, Kufera J, Aarabi B, Scalea T, Sheth K. Mortality and Penetrating Traumatic Brain Injury: Analysis of a 10 Year Cohort (P06.267) Neurology 2012, 78: p06.267-p06.267. DOI: 10.1212/wnl.78.1_meetingabstracts.p06.267.
  • Hemisphere Volume Is Associated with Neurological Deterioration and Outcome after Malignant Infarction (P07.034)Sheth K, Yoo A, Gonzalez R, Kimberly W, Chaudhry Z, Elm J, Jacobson S, Davis S, Donnan G, Albers G, Stern B. Hemisphere Volume Is Associated with Neurological Deterioration and Outcome after Malignant Infarction (P07.034) Neurology 2012, 78: p07.034-p07.034. DOI: 10.1212/wnl.78.1_meetingabstracts.p07.034.
  • Anti-Epileptic Drug Use and Outcome in the Ethnic and Racial Variations in Intracerebral Hemorrhage (ERICH) Study (S23.005)Sheth K, Koch S, Elkind M, Sung G, Kittner S, Frankel M, Rosand J, Langefeld C, Comeau M, Waddy S, Osborne J, Woo D, For the ERICH Investigators. Anti-Epileptic Drug Use and Outcome in the Ethnic and Racial Variations in Intracerebral Hemorrhage (ERICH) Study (S23.005) Neurology 2012, 78: s23.005-s23.005. DOI: 10.1212/wnl.78.1_meetingabstracts.s23.005.
  • The authors replySheth K, Nutter T, Stein D, Scalea T, Bernat J. The authors reply Critical Care Medicine 2012, 40: 708-709. DOI: 10.1097/ccm.0b013e31823d7871.
  • Abstract 2483: No Increased Risk of sICH in tPA Treated Stroke Patients With ECASS Exclusion CriteriaCronin C, Shah N, Morovati T, Hermann L, Sheth K. Abstract 2483: No Increased Risk of sICH in tPA Treated Stroke Patients With ECASS Exclusion Criteria Stroke 2012, 43 DOI: 10.1161/str.43.suppl_1.a2483.
  • Abstract 98: Higher Volume Endovascular Stroke Centers Have Decreased Times to TreatmentGupta R, Horev A, Nguyen T, Gershon R, Gandhi D, Wisco D, Miller B, Tayal A, Ludwig B, Hussain M, Terry J, Jovin T, Belagaje S, Cronin C, Tian M, Anderson A, Frankel M, Sheth K, Liebeskind D, Nogueira R. Abstract 98: Higher Volume Endovascular Stroke Centers Have Decreased Times to Treatment Stroke 2012, 43 DOI: 10.1161/str.43.suppl_1.a98.
  • Abstract 160: Intravenous rt-PA is Not Associated with Increased Risk of Symptomatic Hemorrhage in Patients with Intracranial AneurysmsSheth K, Shah N, Morovati T, Hermann L, Cronin C. Abstract 160: Intravenous rt-PA is Not Associated with Increased Risk of Symptomatic Hemorrhage in Patients with Intracranial Aneurysms Stroke 2012, 43 DOI: 10.1161/str.43.suppl_1.a160.
  • Abstract 207: CT Perfusion Increases Time to Reperfusion and May Not Enhance Patient Selection for Endovascular Reperfusion Therapies in Acute Ischemic StrokeGupta R, Horev A, Wisco D, Tayal A, Miller B, Terry J, Gandhi D, Jovin T, Hussain M, Nguyen T, Ludwig B, Cronin C, Tian M, Sheth K, Nogueira R. Abstract 207: CT Perfusion Increases Time to Reperfusion and May Not Enhance Patient Selection for Endovascular Reperfusion Therapies in Acute Ischemic Stroke Stroke 2012, 43 DOI: 10.1161/str.43.suppl_1.a207.
  • Abstract 3479: Prediction of Outcome in Cerebellar Infarction by Diffusion MRITchopev Z, Zhuo J, Betz J, Gullapalli R, Sheth K. Abstract 3479: Prediction of Outcome in Cerebellar Infarction by Diffusion MRI Stroke 2012, 43 DOI: 10.1161/str.43.suppl_1.a3479.
  • Neurocritical CareSheth K. Neurocritical Care The Neurologist 2011, 17: 120. DOI: 10.1097/nrl.0b013e31820b61f2.
  • Intensive Care Management of Acute Ischemic StrokeSheth K, Greer D. Intensive Care Management of Acute Ischemic Stroke 2007, 163-196. DOI: 10.1002/9780470183397.ch8.

Clinical Trials