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Paul Stabach

Research Associate 3, MS
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Additional Titles

Biotechnology Associate

Contact Info

Yale School of Medicine

Department of Pathology, 310 Cedar Street

New Haven, CT 06520

United States

About

Titles

Research Associate 3, MS

Biotechnology Associate

Biography

A Research Associate/Lab Manager with 30 Years of Molecular/Cellular Biological experience from Yale, MIT, Baylor College of Medicine, Jefferson University, and University of Connecticut Health Center, currently focused on the design and implementation of novel enzyme biologics to treat debilitating pathologies associate with enzyme deficiency.

After an initial success in the Braddock lab with a rare disease of lethal vascular calcifications associated with ENPP1 deficiency called 'Generalized Arterial Calcification of Infancy' (GACI), he then published an article detailing how to improve the potency and longevity of any blood based enzyme biologic (Stabach et.al. Clin Transl Sci. 2020 Oct 16). He is now engineering a new enzyme biologic for the treatment of pathologies associate with the aberrant formation of neutrophil extracellular traps, or netosis. If successful, this biologic could have indications with several pathologies including Lupus, Acute Respiratory Distress Syndrome associated with COVID-19, Cancer metastasis, and coagulopathies such as Deep View Thrombosis and Disseminated Intravascular Coagulation.

Appointments

Departments & Organizations

Education & Training

BS
University of Connecticut (1984)

Research

Overview

Medical Subject Headings (MeSH)

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Chronic Kidney Disease-Mineral and Bone Disorder; Lupus Erythematosus, Systemic; Neutrophil Activation; Purpura, Thrombocytopenic, Idiopathic; Rickets, Hypophosphatemic

Research at a Glance

Yale Co-Authors

Frequent collaborators of Paul Stabach's published research.

Publications

Featured Publications

2024

2022

2021

2020

Get In Touch

Contacts

Academic Office Number
Mobile Phone Number
Mailing Address

Yale School of Medicine

Department of Pathology, 310 Cedar Street

New Haven, CT 06520

United States