Markus Müschen, MD, PhD
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Biography
Markus Müschen, MD-PhD, is the Director of the Center of Molecular and Cellular Oncology, Arthur H. and Isabel Bunker Professor of Hematology, and Professor of Immunobiology at Yale University. He also serves as Chief of the Division of Basic Science of Yale Cancer Center. His research program focuses on signal transduction mechanisms in lymphoid malignancies and how these pathways can be intercepted for the treatment of drug-resistant leukemia and lymphoma. His laboratory established new conceptual frameworks for the understanding of B-cell signaling and energy metabolism and how these mechanisms are altered in lymphoid malignancies.
Markus Müschen studied medicine at the Heinrich-Heine-Universität Düsseldorf, Germany, Université de Nantes, France and the Institut Pasteur, Paris, France. After his clinical training in hematology-oncology with Volker Diehl at the University of Cologne, he completed postdoctoral fellowships in immunology with Klaus Rajewsky and Ralf Küppers and in leukemia genetics with Janet D. Rowley at the University of Chicago.
Before coming to Yale, Markus Müschen’s laboratory was at the University of California San Francisco (UCSF, 2010-2017) where he served as Program Leader of the Hematological Malignancies Program at the UCSF Comprehensive Cancer Center. Markus Müschen is currently a Howard Hughes Medical Institute (HHMI) Faculty Scholar, an elected member of the American Society of Clinical Investigation, the Connecticut Academy of Science and the Scientific Advisory Board of the Lymphoma Research Foundation. His research has been supported by an NCI Outstanding Investigator Award (R35) since 2016. As Director of the Center of Molecular and Cellular Oncology at Yale, he serves as mentor for nine junior faculty.
Müschen Laboratory Drug Discovery platform: http://lymphoblasts.org/
Education & Training
- Visiting Assistant ProfessorChildren's Hospital Los Angeles and University of Southern California (2009)
- Residency and FellowshipUniversity of Cologne (2006)
- PhDInstitute for Genetics Cologne, Immunology (2003)
- MD-PhD thesisUniversity of Cologne (2003)
- Postdoctoral fellowshipUniversity of Chicago (2002)
- Postdoctoral fellowshipInstitute for Genetics, University of Cologne (2000)
- MDHeinrich-Heine-Universität Düsseldorf, Biochemistry (1999)
- MD thesisHeinrich-Heine-Universitaet Duesseldorf (1999)
Honors & Recognition
Award | Awarding Organization | Date |
---|---|---|
Elected Member | Connecticut Academy of Science | 2023 |
NCI Outstanding Investigator Award 2021 | National Cancer Institute | 2021 |
Elected Member, ASCI | American Society of Clinical Investigation | 2019 |
18th Annual Maxwell M. Wintrobe Endowed Lecture | University of Utah | 2018 |
Stephen D. Williams, MD, Lectureship | Indiana University | 2018 |
20th Andrew I. Schafer Distinguished Lecture | Cornell University | 2018 |
Norman and Sadie Lee Foundation Endowed Chair | Norman and Sadie Lee Foundation | 2017 |
NCI Outstanding Investigator Award (R35) | National Cancer Institute | 2016 |
Howard Hughes Medical Institute Faculty Scholar Award | Howard Hughes Medical Institute | 2016 |
Cancer Research UK Programme Award | Cancer Research UK | 2014 |
Honorary faculty appointment | Cambridge University | 2014 |
Wellcome Trust Senior Investigator Award | Wellcome Trust | 2013 |
Sir Alexander Haddow Professorship | The Institute for Cancer Research (ICR) | 2012 |
Scholar Award | Leukemia and Lymphoma Society | 2011 |
Stand Up To Cancer Innovation | American Association for Cancer Research | 2009 |
Leukemia Clinical Research Award | German Society of Hematology and Oncology | 2006 |
Fritz-Melchers-Award in Immunology | German Association of Immunologists | 2003 |
Emmy-Noether-Award | German Science Foundation (DFG) | 2002 |
Irvington Postdoctoral Fellowship Award | Cancer Research Institute | 2000 |
Professional Service
Organization | Role | Date |
---|---|---|
Scientific Advisory Board, Lymphoma Research Foundation | Member | 2023 - Present |
Scientific Advisory Board, The Blood Research Institute, Milwaukee, WI | Member | 2021 - Present |
Hôpital Necker-Enfants Malades Scientific Advisory Board, Hôpital Necker-Enfants Malades | Scientific Advisor | 2018 - Present |
NIH Molecular Oncogenesis (MONC) study section | Member | 2016 - Present |
Biological Chemistry | Associate Editor | 2009 - Present |
Leukemia, Nature Publishing Group | Associate Editor | 2008 - 2014 |