Etienne Leveille, MD, PhD
Instructor of Medicine (Medical Oncology & Hematology)DownloadHi-Res Photo
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Instructor of Medicine (Medical Oncology & Hematology)
Biography
Etienne Leveille is a hematology & oncology fellow in the ABIM Physician-Scientist Research Pathway at the Yale School of Medicine. He completed his medical school at McGill University, where he also studied the genetics of Parkinson’s disease and hereditary spastic paraplegia under the supervision of Dr. Ziv Gan-Or and mechanisms of inhibition of apoptosis in diffuse large B-cell lymphoma with Dr. Nathalie Johnson. While at McGill , Etienne was also the Co-Editor-in-Chief of the McGill Journal of Medicine. Etienne is a member of the Center of Molecular and Cellular Oncology and studies ferroptosis and other novel therapeutic approaches in B-cell malignancies under the mentorship of Dr. Markus Müschen.
Last Updated on August 02, 2024.
Appointments
Medical Oncology and Hematology
InstructorPrimary
Other Departments & Organizations
- ABIM Physician-Scientist Research Pathway
- Center of Molecular and Cellular Oncology
- Internal Medicine
- Medical Oncology and Hematology
- Müschen Lab
- Yale Medicine
Education & Training
- PhD
- Yale University (2026)
- MD
- McGill University (2021)
Research
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Research at a Glance
Yale Co-Authors
Frequent collaborators of Etienne Leveille's published research.
Publications Timeline
A big-picture view of Etienne Leveille's research output by year.
Jennifer M. Kwan, MD, PhD
Markus Müschen, MD, PhD
Giulia Biancon, PhD
Jennifer VanOudenhove, PhD
Kohei Kume, PhD
Shalin Kothari, MD
18Publications
48Citations
Publications
2024
Clonal Hematopoiesis Is Associated With Cardiomyopathy During Solid Tumor Therapy
Leveille E, Cheheyeb R, Matute-Martinez C, Chen N, Jayakrishnan R, Christofides A, Lin D, Im Y, Biancon G, VanOudenhove J, Halene S, Kwan J. Clonal Hematopoiesis Is Associated With Cardiomyopathy During Solid Tumor Therapy. JACC CardioOncology 2024, 6: 605-607. PMID: 39239339, PMCID: PMC11372300, DOI: 10.1016/j.jaccao.2024.05.013.Peer-Reviewed Original ResearchCitationsAltmetricImpact of COVID-19 pandemic on physician-scientist trainees to faculty one year into the pandemic
Obradovic A, Toubat O, Chen N, Siebert A, Jansen C, Christophers B, Leveille E, Noch E, Kwan J. Impact of COVID-19 pandemic on physician-scientist trainees to faculty one year into the pandemic. BMC Medical Education 2024, 24: 587. PMID: 38807106, PMCID: PMC11134762, DOI: 10.1186/s12909-024-05541-9.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPersonal healthLong-term effects of COVID-19Physician-scientist traineesPhysician-scientistsCross-sectional survey of medical studentsCOVID-19 pandemicSurvey of medical studentsClustering techniqueScientific pursuitsHealth of familiesMultivariate regression analysisEffects of COVID-19ConclusionsThis national surveyLevel of trainingTailored supportPhysician-scientist trainingResearch productivityMental healthFewer physiciansLonger-term impactMedical studentsImpaired productionCOVID-19Long-term effectsReport concerns
2022
Genetic Modeling of B-cell State Transitions for Rational Design of Lymphoma Therapies.
Leveille E, Kothari S, Müschen M. Genetic Modeling of B-cell State Transitions for Rational Design of Lymphoma Therapies. Blood Cancer Discovery 2022, 4: 8-11. PMID: 36534735, PMCID: PMC9816816, DOI: 10.1158/2643-3230.bcd-22-0180.Commentaries, Editorials and LettersCitationsAltmetricSYK and ZAP70 kinases in autoimmunity and lymphoid malignancies
Leveille E, Chan LN, Mirza AS, Kume K, Müschen M. SYK and ZAP70 kinases in autoimmunity and lymphoid malignancies. Cellular Signalling 2022, 94: 110331. PMID: 35398488, DOI: 10.1016/j.cellsig.2022.110331.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetricMeSH Keywords and ConceptsConceptsChronic lymphocytic leukemiaB-cell malignanciesT cell receptorB cell receptorB-cell chronic lymphocytic leukemiaPathological B-cellsPoor clinical outcomeAcute lymphoblastic leukemiaExpression of SykT lymphocyte developmentClinical outcomesAggressive diseaseActivation of NFATAutoimmune diseasesLymphoblastic leukemiaT lymphocytesLymphocytic leukemiaCell lymphomaLymphoid malignanciesB cellsPI3K-pathwayOncogenic driversMalignancyNegative selectionPremalignant cells
2021
GCH1 mutations in hereditary spastic paraplegia.
Varghaei P, Yoon G, Estiar MA, Veyron S, Leveille E, Dupré N, Trempe JF, Rouleau GA, Gan-Or Z. GCH1 mutations in hereditary spastic paraplegia. Clinical Genetics 2021, 100: 51-58. PMID: 33713342, DOI: 10.1111/cge.13955.Peer-Reviewed Original ResearchMetabolic determinants of B-cell selection
Chan LN, Aghania E, Leveille E, Müschen M. Metabolic determinants of B-cell selection. Biochemical Society Transactions 2021, 49: 1467-1478. PMID: 34196360, DOI: 10.1042/bst20201316.BooksCitationsAltmetricMeSH Keywords and ConceptsConceptsB cellsAutoimmune diseasesB cell selectionB cell developmentImmune systemNegative B cell selectionRisk of developmentAutoreactive B cellsB-cell malignanciesAdaptive immune protectionAdaptive immune systemAntibody-producing cellsPremalignant B cellsEarly B cell developmentHarmful autoantibodiesHigh-affinity antibodiesImmune protectionAutoreactive clonesChronic restrictionBone marrowMalignant transformationMetabolic determinantsDiseaseLymphomaLeukemiaGenetic Events Inhibiting Apoptosis in Diffuse Large B Cell Lymphoma.
Leveille E, Johnson NA. Genetic Events Inhibiting Apoptosis in Diffuse Large B Cell Lymphoma. Cancers 2021, 13 PMID: 33946435, PMCID: PMC8125500, DOI: 10.3390/cancers13092167.Peer-Reviewed Original ResearchInvestigating the relationship between the SNCA gene and cognitive abilities in idiopathic Parkinson's disease using machine learning.
Ramezani M, Mouches P, Yoon E, Rajashekar D, Ruskey JA, Leveille E, Martens K, Kibreab M, Hammer T, Kathol I, Maarouf N, Sarna J, Martino D, Pfeffer G, Gan-Or Z, Forkert ND, Monchi O. Investigating the relationship between the SNCA gene and cognitive abilities in idiopathic Parkinson's disease using machine learning. Scientific Reports 2021, 11: 4917. PMID: 33649398, PMCID: PMC7921412, DOI: 10.1038/s41598-021-84316-4.Peer-Reviewed Original ResearchEvidence for Non-Mendelian Inheritance in Spastic Paraplegia 7.
Estiar MA, Yu E, Haj Salem I, Ross JP, Mufti K, Akçimen F, Leveille E, Spiegelman D, Ruskey JA, Asayesh F, Dagher A, Yoon G, Tarnopolsky M, Boycott KM, Dupre N, Dion PA, Suchowersky O, Trempe JF, Rouleau GA, Gan-Or Z. Evidence for Non-Mendelian Inheritance in Spastic Paraplegia 7. Movement Disorders : Official Journal Of The Movement Disorder Society 2021 PMID: 33598982, DOI: 10.1002/mds.28528.Peer-Reviewed Original Research
2020
GBA variants in REM sleep behavior disorder: A multicenter study.
Krohn L, Ruskey JA, Rudakou U, Leveille E, Asayesh F, Hu MTM, Arnulf I, Dauvilliers Y, Högl B, Stefani A, Monaca CC, Abril B, Plazzi G, Antelmi E, Ferini-Strambi L, Heidbreder A, Boeve BF, Espay AJ, De Cock VC, Mollenhauer B, Sixel-Döring F, Trenkwalder C, Sonka K, Kemlink D, Figorilli M, Puligheddu M, Dijkstra F, Viaene M, Oertel W, Toffoli M, Gigli GL, Valente M, Gagnon JF, Desautels A, Montplaisir JY, Postuma RB, Rouleau GA, Gan-Or Z. GBA variants in REM sleep behavior disorder: A multicenter study. Neurology 2020, 95: e1008-e1016. PMID: 32591474, PMCID: PMC7668554, DOI: 10.1212/WNL.0000000000010042.Peer-Reviewed Original Research
News
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News
- January 08, 2026
Yale-Led Study Identifies a New Target for Treating Acute Leukemia
- December 09, 2025
Yale research advances presented at American Society of Hematology annual meeting
- June 04, 2025
Lymphoma Research Foundation Awards Dr. Etienne Leveille a Postdoctoral Fellowship Grant
- August 16, 2023
Welcome New Postdocs, Postgrads, Fellows, Faculty & Staff! (August 2023)
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