Alfred Lee, MD, PhD
Professor of Medicine (Hematology)Cards
About
Research
Publications
2026
The hematology workforce in the United States: past, present, and strategies for the future
Lee A, Masselink L, Naik R, Carraway H, Connell N, DeCastro L, Dent G, DiMichele D, Ellis L, Gómez-De León A, Loren A, Lucas T, Marshall A, Mims M, Nelson M, Nagalla S, O'Connell C, Park S, Rajasekhar A, Sharma D, Smith M, Weeks L, Wun T, Fritz J, Reynolds R, Van Havre N, Erikson C. The hematology workforce in the United States: past, present, and strategies for the future. Blood Advances 2026 PMID: 42600160, DOI: 10.1182/bloodadvances.2025019451.Peer-Reviewed Original ResearchBurnout in sickle cell disease–focused hematology-oncology–trained physicians: a national cross-sectional study
Restrepo-Espinosa V, Marshall A, Feder K, Afranie-Sakyi J, Carrithers B, Jones-Wonni B, Mensah C, Zhou B, Mistry R, McGann P, Azar S, De Castro L, Calhoun C, Boozang K, Brown T, Lee A, Van Doren L. Burnout in sickle cell disease–focused hematology-oncology–trained physicians: a national cross-sectional study. Blood Advances 2026, 10: 3653-3663. PMID: 41817318, PMCID: PMC13207547, DOI: 10.1182/bloodadvances.2025018338.Peer-Reviewed Original ResearchThis study investigates burnout in U.S. hematology-oncology physicians specializing in sickle cell disease, showing higher burnout rates linked to institutional and workplace challenges, reduced recreation, and lower job pride.Anemia of Inflammation
Lee A. Anemia of Inflammation. 2026, 33-36. DOI: 10.1007/978-3-032-13858-3_5.BooksProspective Evaluation of Large Language Model Integration Into a Classical Hematology Case Conference
Kewan T, Lee A, Van Doren L. Prospective Evaluation of Large Language Model Integration Into a Classical Hematology Case Conference. JMIR Formative Research 2026, 10: e89939. PMID: 41849561, PMCID: PMC12998601, DOI: 10.2196/89939.Peer-Reviewed Original ResearchUtilization patterns of hematology consultation in the intensive care unit: an 11-year single-center experience
Allen C, Streiff M, Naik R, Seam N, Kadri S, Lee A, Knauert M, Goshua G. Utilization patterns of hematology consultation in the intensive care unit: an 11-year single-center experience. Blood Advances 2026, 10: 1943-1946. PMID: 41348859, PMCID: PMC12995476, DOI: 10.1182/bloodadvances.2025018327.Peer-Reviewed Original ResearchThis study investigates hematology consultation patterns in ICUs, finding most queries address nonmalignant conditions like thrombocytopenia and coagulopathy, highlighting training and resource gaps.Thrombopoietin-Receptor Agonists in Chemotherapy-Induced Thrombocytopenia
Goshua G, Lee A. Thrombopoietin-Receptor Agonists in Chemotherapy-Induced Thrombocytopenia. The New England Journal Of Medicine 2026, 394: 1125-1126. PMID: 41812200, DOI: 10.1056/nejme2517578.Commentaries, Editorials and LettersCost-effectiveness of first-line IV vs oral iron for iron-deficiency anemia in women with heavy menstrual bleeding
Wang D, Sra M, Ito S, Ng D, Glaeser-Khan S, Wang D, Hirniak S, Lee A, Cuker A, Goshua G. Cost-effectiveness of first-line IV vs oral iron for iron-deficiency anemia in women with heavy menstrual bleeding. Blood Advances 2026, 10: 1508-1517. PMID: 41504430, PMCID: PMC12952766, DOI: 10.1182/bloodadvances.2025018315.Peer-Reviewed Original Research
2025
When genotype and phenotype disagree: rethinking thrombophilia testing in the genomic era
Ryu J, Lee A. When genotype and phenotype disagree: rethinking thrombophilia testing in the genomic era. Journal Of Thrombosis And Haemostasis 2025, 23: 3806-3808. PMID: 41260738, DOI: 10.1016/j.jtha.2025.07.044.Peer-Reviewed Original ResearchMolecular clues to venous thromboembolism recurrence
Ryu J, Lee A. Molecular clues to venous thromboembolism recurrence. Blood 2025, 146: 2281-2282. PMID: 41196621, DOI: 10.1182/blood.2025030460.Commentaries, Editorials and LettersA proteomic map of thromboinflammatory signatures in antiphospholipid syndrome: results from antiphospholipid syndrome alliance for clinical trials and international networking (APS ACTION) registry
Pine A, Butt A, Andreoli L, Knight J, Gerosa M, Cecchi I, Branch D, Lopez-Pedrera R, Belmont H, Kello N, Petri M, Cervera R, Pengo V, Meroni P, Cohen H, Willis R, Bertolaccini M, Goshua G, Gu S, Hwa J, Lee A, Erkan D, Sharda A. A proteomic map of thromboinflammatory signatures in antiphospholipid syndrome: results from antiphospholipid syndrome alliance for clinical trials and international networking (APS ACTION) registry. Frontiers In Immunology 2025, 16: 1676578. PMID: 41181143, PMCID: PMC12571811, DOI: 10.3389/fimmu.2025.1676578.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
News & Links
News
- March 19, 2026Source: Medscape (with Drs. Alfred Lee and George Goshua)
Can Romiplostim Reduce Chemotherapy Disruptions in GI Cancer?
- December 09, 2025
Yale research advances presented at American Society of Hematology annual meeting
- December 01, 2025
Yale Cancer Center Experts to Present Latest Findings at American Society of Hematology’s Annual Meeting
- February 06, 2025Source: Medscape
Compassion Fatigue: How Oncologists Can Recognize the Signs
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