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Shu-Xia Li, PhD

Staff Affiliate - YNHH; Associate Director, Data Management & Analytics, Center for Outcomes Research & Evaluation (CORE)

Research & Publications
Biography
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Coauthors

Selected Publications

Three-Month Symptom Profiles Among Symptomatic Adults With Positive and Negative Severe Acute Respiratory Syndrome Coronavirus 2 Tests: A Prospective Cohort Study From the INSPIRE Group.Spatz E, Gottlieb M, Wisk L, Anderson J, Chang A, Gentile N, Hill M, Huebinger R, Idris A, Kinsman J, Koo K, Li S, McDonald S, Plumb I, Rodriguez R, Saydah S, Slovis B, Stephens K, Unger E, Wang R, Yu H, Hota B, Elmore J, Weinstein R, Venkatesh A. Three-Month Symptom Profiles Among Symptomatic Adults With Positive and Negative Severe Acute Respiratory Syndrome Coronavirus 2 Tests: A Prospective Cohort Study From the INSPIRE Group. Clinical Infectious Diseases 2022, 76: 1559-1566. PMID: 36573005, DOI: 10.1093/cid/ciac966.
Uncoupling of all-cause excess mortality from COVID-19 cases in a highly vaccinated stateFaust JS, Renton B, Chen AJ, Du C, Liang C, Li SX, Lin Z, Krumholz HM. Uncoupling of all-cause excess mortality from COVID-19 cases in a highly vaccinated state. The Lancet Infectious Diseases 2022, 22: 1419-1420. PMID: 36007530, PMCID: PMC9395168, DOI: 10.1016/s1473-3099(22)00547-3.
Sex-Specific Risk Factors Associated With First Acute Myocardial Infarction in Young AdultsLu Y, Li SX, Liu Y, Rodriguez F, Watson KE, Dreyer RP, Khera R, Murugiah K, D’Onofrio G, Spatz ES, Nasir K, Masoudi FA, Krumholz HM. Sex-Specific Risk Factors Associated With First Acute Myocardial Infarction in Young Adults. JAMA Network Open 2022, 5: e229953. PMID: 35503221, PMCID: PMC9066284, DOI: 10.1001/jamanetworkopen.2022.9953.
Leading Causes of Death Among Adults Aged 25 to 44 Years by Race and Ethnicity in Texas During the COVID-19 Pandemic, March to December 2020Faust JS, Chen AJ, Tiako M, Du C, Li SX, Krumholz HM, Barnett ML. Leading Causes of Death Among Adults Aged 25 to 44 Years by Race and Ethnicity in Texas During the COVID-19 Pandemic, March to December 2020. JAMA Internal Medicine 2022, 182: 87-90. PMID: 34807250, PMCID: PMC8609460, DOI: 10.1001/jamainternmed.2021.6734.
Performance Metrics for the Comparative Analysis of Clinical Risk Prediction Models Employing Machine LearningHuang C, Li SX, Caraballo C, Masoudi FA, Rumsfeld JS, Spertus JA, Normand ST, Mortazavi BJ, Krumholz HM. Performance Metrics for the Comparative Analysis of Clinical Risk Prediction Models Employing Machine Learning. Circulation Cardiovascular Quality And Outcomes 2021, 14: e007526. PMID: 34601947, DOI: 10.1161/circoutcomes.120.007526.
Disparities in Excess Mortality Associated with COVID-19 — United States, 2020Rossen LM, Ahmad FB, Anderson RN, Branum AM, Du C, Krumholz HM, Li SX, Lin Z, Marshall A, Sutton PD, Faust JS. Disparities in Excess Mortality Associated with COVID-19 — United States, 2020. MMWR Morbidity And Mortality Weekly Report 2021, 70: 1114-1119. PMID: 34411075, PMCID: PMC8375709, DOI: 10.15585/mmwr.mm7033a2.
Mortality From Drug Overdoses, Homicides, Unintentional Injuries, Motor Vehicle Crashes, and Suicides During the Pandemic, March-August 2020Faust JS, Du C, Mayes KD, Li SX, Lin Z, Barnett ML, Krumholz HM. Mortality From Drug Overdoses, Homicides, Unintentional Injuries, Motor Vehicle Crashes, and Suicides During the Pandemic, March-August 2020. JAMA 2021, 326: 84-86. PMID: 34019096, PMCID: PMC8140390, DOI: 10.1001/jama.2021.8012.
Incorporating Present-on-Admission Indicators in Medicare Claims to Inform Hospital Quality Measure Risk Adjustment ModelsTriche EW, Xin X, Stackland S, Purvis D, Harris A, Yu H, Grady JN, Li SX, Bernheim SM, Krumholz HM, Poyer J, Dorsey K. Incorporating Present-on-Admission Indicators in Medicare Claims to Inform Hospital Quality Measure Risk Adjustment Models. JAMA Network Open 2021, 4: e218512. PMID: 33978722, PMCID: PMC8116982, DOI: 10.1001/jamanetworkopen.2021.8512.
Delays in antibiotic redosing: Association with inpatient mortality and risk factors for delayKemmler CB, Sangal RB, Rothenberg C, Li SX, Shofer FS, Abella BS, Venkatesh AK, Foster SD. Delays in antibiotic redosing: Association with inpatient mortality and risk factors for delay. The American Journal Of Emergency Medicine 2021, 46: 63-69. PMID: 33735698, DOI: 10.1016/j.ajem.2021.02.058.
SARS-CoV-2 Infection Hospitalization Rate and Infection Fatality Rate Among the Non-Congregate Population in ConnecticutMahajan S, Caraballo C, Li SX, Dong Y, Chen L, Huston SK, Srinivasan R, Redlich CA, Ko AI, Faust JS, Forman HP, Krumholz HM. SARS-CoV-2 Infection Hospitalization Rate and Infection Fatality Rate Among the Non-Congregate Population in Connecticut. The American Journal Of Medicine 2021, 134: 812-816.e2. PMID: 33617808, PMCID: PMC7895685, DOI: 10.1016/j.amjmed.2021.01.020.
Suicide Deaths During the COVID-19 Stay-at-Home Advisory in Massachusetts, March to May 2020Faust JS, Shah SB, Du C, Li SX, Lin Z, Krumholz HM. Suicide Deaths During the COVID-19 Stay-at-Home Advisory in Massachusetts, March to May 2020. JAMA Network Open 2021, 4: e2034273. PMID: 33475750, PMCID: PMC7821026, DOI: 10.1001/jamanetworkopen.2020.34273.
Seroprevalence of SARS-CoV-2-Specific IgG Antibodies Among Adults Living in Connecticut: Post-Infection Prevalence (PIP) StudyMahajan S, Srinivasan R, Redlich CA, Huston SK, Anastasio KM, Cashman L, Massey DS, Dugan A, Witters D, Marlar J, Li SX, Lin Z, Hodge D, Chattopadhyay M, Adams MD, Lee C, Rao LV, Stewart C, Kuppusamy K, Ko AI, Krumholz HM. Seroprevalence of SARS-CoV-2-Specific IgG Antibodies Among Adults Living in Connecticut: Post-Infection Prevalence (PIP) Study. The American Journal Of Medicine 2020, 134: 526-534.e11. PMID: 33130124, PMCID: PMC7598362, DOI: 10.1016/j.amjmed.2020.09.024.
Timely estimation of National Admission, readmission, and observation-stay rates in medicare patients with acute myocardial infarction, heart failure, or pneumonia using near real-time claims dataLi SX, Wang Y, Lama SD, Schwartz J, Herrin J, Mei H, Lin Z, Bernheim SM, Spivack S, Krumholz HM, Suter LG. Timely estimation of National Admission, readmission, and observation-stay rates in medicare patients with acute myocardial infarction, heart failure, or pneumonia using near real-time claims data. BMC Health Services Research 2020, 20: 733. PMID: 32778098, PMCID: PMC7416804, DOI: 10.1186/s12913-020-05611-w.
Surgeons: Buyer beware—does “universal” risk prediction model apply to patients universally?Mori M, Shahian DM, Huang C, Li SX, Normand ST, Geirsson A, Krumholz HM. Surgeons: Buyer beware—does “universal” risk prediction model apply to patients universally? Journal Of Thoracic And Cardiovascular Surgery 2020, 160: 176-179.e2. PMID: 32241616, DOI: 10.1016/j.jtcvs.2019.11.144.
Development and Validation of a Model for Predicting the Risk of Acute Kidney Injury Associated With Contrast Volume Levels During Percutaneous Coronary InterventionHuang C, Li SX, Mahajan S, Testani JM, Wilson FP, Mena CI, Masoudi FA, Rumsfeld JS, Spertus JA, Mortazavi BJ, Krumholz HM. Development and Validation of a Model for Predicting the Risk of Acute Kidney Injury Associated With Contrast Volume Levels During Percutaneous Coronary Intervention. JAMA Network Open 2019, 2: e1916021. PMID: 31755952, PMCID: PMC6902830, DOI: 10.1001/jamanetworkopen.2019.16021.
More Considerations on Both Model Assumptions and Results Interpretations—Evaluating ReadmissionDu C, Zhou G, Li SX. More Considerations on Both Model Assumptions and Results Interpretations—Evaluating Readmission. JAMA Internal Medicine 2019, 179: 1599-1599. PMID: 31682690, DOI: 10.1001/jamainternmed.2019.4688.
Substantial Differences Between Cohorts of Patients Hospitalized With Heart Failure in Canada and the United StatesLin Z, Li SX. Substantial Differences Between Cohorts of Patients Hospitalized With Heart Failure in Canada and the United States. JAMA Cardiology 2019, 4: 1178-1179. PMID: 31532467, DOI: 10.1001/jamacardio.2019.3314.
Development and Testing of Improved Models to Predict Payment Using Centers for Medicare & Medicaid Services Claims DataKrumholz HM, Warner F, Coppi A, Triche EW, Li SX, Mahajan S, Li Y, Bernheim SM, Grady J, Dorsey K, Desai NR, Lin Z, Normand ST. Development and Testing of Improved Models to Predict Payment Using Centers for Medicare & Medicaid Services Claims Data. JAMA Network Open 2019, 2: e198406. PMID: 31411709, PMCID: PMC6694388, DOI: 10.1001/jamanetworkopen.2019.8406.
Comparative Effectiveness of New Approaches to Improve Mortality Risk Models From Medicare Claims DataKrumholz HM, Coppi AC, Warner F, Triche EW, Li SX, Mahajan S, Li Y, Bernheim SM, Grady J, Dorsey K, Lin Z, Normand ST. Comparative Effectiveness of New Approaches to Improve Mortality Risk Models From Medicare Claims Data. JAMA Network Open 2019, 2: e197314. PMID: 31314120, PMCID: PMC6647547, DOI: 10.1001/jamanetworkopen.2019.7314.
Association Between Insurance Status and Access to Hospital Care in Emergency Department DispositionVenkatesh AK, Chou SC, Li SX, Choi J, Ross JS, D’Onofrio G, Krumholz HM, Dharmarajan K. Association Between Insurance Status and Access to Hospital Care in Emergency Department Disposition. JAMA Internal Medicine 2019, 179: 686-693. PMID: 30933243, PMCID: PMC6503571, DOI: 10.1001/jamainternmed.2019.0037.
Association of in-hospital resource utilization with post-acute spending in Medicare beneficiaries hospitalized for acute myocardial infarction: a cross-sectional studyNuti SV, Li SX, Xu X, Ott LS, Lagu T, Desai NR, Murugiah K, Duan M, Martin J, Kim N, Krumholz HM. Association of in-hospital resource utilization with post-acute spending in Medicare beneficiaries hospitalized for acute myocardial infarction: a cross-sectional study. BMC Health Services Research 2019, 19: 190. PMID: 30909904, PMCID: PMC6432744, DOI: 10.1186/s12913-019-4018-0.
Enhancing the prediction of acute kidney injury risk after percutaneous coronary intervention using machine learning techniques: A retrospective cohort studyHuang C, Murugiah K, Mahajan S, Li SX, Dhruva SS, Haimovich JS, Wang Y, Schulz WL, Testani JM, Wilson FP, Mena CI, Masoudi FA, Rumsfeld JS, Spertus JA, Mortazavi BJ, Krumholz HM. Enhancing the prediction of acute kidney injury risk after percutaneous coronary intervention using machine learning techniques: A retrospective cohort study. PLOS Medicine 2018, 15: e1002703. PMID: 30481186, PMCID: PMC6258473, DOI: 10.1371/journal.pmed.1002703.
The Relationship Between Nutritional Risks and Cancer-Related Fatigue in Patients With Colorectal Cancer Fast-Track Surgery.Wei JN, Li SX. The Relationship Between Nutritional Risks and Cancer-Related Fatigue in Patients With Colorectal Cancer Fast-Track Surgery. Cancer Nursing 2018, 41: E41-E47. PMID: 29049040, DOI: 10.1097/NCC.0000000000000541.
Quantifying the utilization of medical devices necessary to detect postmarket safety differences: A case study of implantable cardioverter defibrillatorsBates J, Parzynski CS, Dhruva SS, Coppi A, Kuntz R, Li S, Marinac‐Dabic D, Masoudi FA, Shaw RE, Warner F, Krumholz HM, Ross JS. Quantifying the utilization of medical devices necessary to detect postmarket safety differences: A case study of implantable cardioverter defibrillators. Pharmacoepidemiology And Drug Safety 2018, 27: 848-856. PMID: 29896873, PMCID: PMC6436550, DOI: 10.1002/pds.4565.
Systolic Blood Pressure Response in SPRINT (Systolic Blood Pressure Intervention Trial) and ACCORD (Action to Control Cardiovascular Risk in Diabetes): A Possible Explanation for Discordant Trial ResultsHuang C, Dhruva SS, Coppi AC, Warner F, Li S, Lin H, Nasir K, Krumholz HM. Systolic Blood Pressure Response in SPRINT (Systolic Blood Pressure Intervention Trial) and ACCORD (Action to Control Cardiovascular Risk in Diabetes): A Possible Explanation for Discordant Trial Results. Journal Of The American Heart Association 2017, 6: e007509. PMID: 29133522, PMCID: PMC5721802, DOI: 10.1161/jaha.117.007509.
Can machine learning complement traditional medical device surveillance? A case-study of dual-chamber implantable cardioverter–defibrillatorsRoss JS, Bates J, Parzynski CS, Akar JG, Curtis JP, Desai NR, Freeman JV, Gamble GM, Kuntz R, Li SX, Marinac-Dabic D, Masoudi FA, Normand ST, Ranasinghe I, Shaw RE, Krumholz HM. Can machine learning complement traditional medical device surveillance? A case-study of dual-chamber implantable cardioverter–defibrillators. Medical Devices Evidence And Research 2017, 10: 165-188. PMID: 28860874, PMCID: PMC5566316, DOI: 10.2147/mder.s138158.
Heterogeneity in Early Responses in ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial)Dhruva SS, Huang C, Spatz ES, Coppi AC, Warner F, Li SX, Lin H, Xu X, Furberg CD, Davis BR, Pressel SL, Coifman RR, Krumholz HM. Heterogeneity in Early Responses in ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial). Hypertension 2017, 70: 94-102. PMID: 28559399, DOI: 10.1161/hypertensionaha.117.09221.
Discovery of temporal and disease association patterns in condition-specific hospital utilization ratesHaimovich JS, Venkatesh AK, Shojaee A, Coppi A, Warner F, Li SX, Krumholz HM. Discovery of temporal and disease association patterns in condition-specific hospital utilization rates. PLOS ONE 2017, 12: e0172049. PMID: 28355219, PMCID: PMC5371293, DOI: 10.1371/journal.pone.0172049.
TOWARD IDENTIFYING PERSONALIZED PROGNOSIS IN HYPERTENSION: VARIATION IN EARLY RESPONSES IN THE ANTIHYPERTENSIVE AND LIPID-LOWERING TREATMENT TO PREVENT HEART ATTACK TRIAL (ALLHAT)Dhruva S, Huang C, Spatz E, Coppi A, Warner F, Li S, Lin H, Xu X, Furberg C, Davis B, Pressel S, Coifman R, Krumholz H. TOWARD IDENTIFYING PERSONALIZED PROGNOSIS IN HYPERTENSION: VARIATION IN EARLY RESPONSES IN THE ANTIHYPERTENSIVE AND LIPID-LOWERING TREATMENT TO PREVENT HEART ATTACK TRIAL (ALLHAT). Journal Of The American College Of Cardiology 2017, 69: 1762. DOI: 10.1016/s0735-1097(17)35151-3.
Analysis of Machine Learning Techniques for Heart Failure ReadmissionsMortazavi BJ, Downing NS, Bucholz EM, Dharmarajan K, Manhapra A, Li SX, Negahban SN, Krumholz HM. Analysis of Machine Learning Techniques for Heart Failure Readmissions. Circulation Cardiovascular Quality And Outcomes 2016, 9: 629-640. PMID: 28263938, PMCID: PMC5459389, DOI: 10.1161/circoutcomes.116.003039.
Hospital Phenotypes in the Management of Patients Admitted for Acute Myocardial InfarctionXu X, Li SX, Lin H, Normand SL, Lagu T, Desai N, Duan M, Kroch EA, Krumholz HM. Hospital Phenotypes in the Management of Patients Admitted for Acute Myocardial Infarction. Medical Care 2016, 54: 929-936. PMID: 27261637, PMCID: PMC5305177, DOI: 10.1097/mlr.0000000000000571.
Identification of Hospital Cardiac Services for Acute Myocardial Infarction Using Individual Patient Discharge DataChang TE, Krumholz HM, Li S, Martin J, Ranasinghe I. Identification of Hospital Cardiac Services for Acute Myocardial Infarction Using Individual Patient Discharge Data. Journal Of The American Heart Association 2016, 5: e003680. PMID: 27628573, PMCID: PMC5079029, DOI: 10.1161/jaha.116.003680.
Treatment for Multiple Acute Cardiopulmonary Conditions in Older Adults Hospitalized with Pneumonia, Chronic Obstructive Pulmonary Disease, or Heart FailureDharmarajan K, Strait KM, Tinetti ME, Lagu T, Lindenauer PK, Lynn J, Krukas MR, Ernst FR, Li SX, Krumholz HM. Treatment for Multiple Acute Cardiopulmonary Conditions in Older Adults Hospitalized with Pneumonia, Chronic Obstructive Pulmonary Disease, or Heart Failure. Journal Of The American Geriatrics Society 2016, 64: 1574-1582. PMID: 27448329, PMCID: PMC4988873, DOI: 10.1111/jgs.14303.
The china patient‐centered evaluative assessment of cardiac events (PEACE) prospective study of percutaneous coronary intervention: Study designDu X, Pi Y, Dreyer RP, Li J, Li X, Downing NS, Li L, Feng F, Zhan L, Zhang H, Guan W, Xu X, Li S, Lin Z, Masoudi FA, Spertus JA, Krumholz HM, Jiang L, Group F. The china patient‐centered evaluative assessment of cardiac events (PEACE) prospective study of percutaneous coronary intervention: Study design. Catheterization And Cardiovascular Interventions 2016, 88: e212-e221. PMID: 26945565, PMCID: PMC5215582, DOI: 10.1002/ccd.26461.
China Patient-centered Evaluative Assessment of Cardiac Events Prospective Study of Acute Myocardial Infarction: Study DesignLi J, Dreyer RP, Li X, Du X, Downing NS, Li L, Zhang HB, Feng F, Guan WC, Xu X, Li SX, Lin ZQ, Masoudi FA, Spertus JA, Krumholz HM, Jiang LX, Group T. China Patient-centered Evaluative Assessment of Cardiac Events Prospective Study of Acute Myocardial Infarction: Study Design. Chinese Medical Journal 2016, 129: 72-80. PMID: 26712436, PMCID: PMC4797546, DOI: 10.4103/0366-6999.172596.
Hospital variation in admission to intensive care units for patients with acute myocardial infarctionChen R, Strait KM, Dharmarajan K, Li SX, Ranasinghe I, Martin J, Fazel R, Masoudi FA, Cooke CR, Nallamothu BK, Krumholz HM. Hospital variation in admission to intensive care units for patients with acute myocardial infarction. American Heart Journal 2015, 170: 1161-1169. PMID: 26678638, PMCID: PMC5459386, DOI: 10.1016/j.ahj.2015.09.003.
Hospital Variability in Use of Anticoagulant Strategies During Acute Myocardial Infarction Treated With an Early Invasive StrategyArnold SV, Li SX, Alexander KP, Spertus JA, Nallamothu BK, Curtis JP, Kosiborod M, Gupta A, Wang TY, Lin H, Dharmarajan K, Strait KM, Lowe TJ, Krumholz HM. Hospital Variability in Use of Anticoagulant Strategies During Acute Myocardial Infarction Treated With an Early Invasive Strategy. Journal Of The American Heart Association 2015, 4: e002009. PMID: 26077589, PMCID: PMC4599539, DOI: 10.1161/jaha.115.002009.
Abstract 377: The China Patient-Centered Evaluative Assessment of Cardiac Events (PEACE) Prospective Study of Percutaneous Coronary Intervention: Study DesignDu X, Pi Y, Dreyer R, Li J, Li X, Downing N, Li L, Feng F, Zhan L, Zhang H, Guan W, Xu X, Li S, Lin Z, Masoudi F, Spertus J, Krumholz H, Jiang L. Abstract 377: The China Patient-Centered Evaluative Assessment of Cardiac Events (PEACE) Prospective Study of Percutaneous Coronary Intervention: Study Design. Circulation Cardiovascular Quality And Outcomes 2015, 8 DOI: 10.1161/circoutcomes.8.suppl_2.377.
Abstract 278: The China Patient-Centered Evaluative Assessment of Cardiac Events (PEACE) Prospective Study of Acute Myocardial Infarction: Study DesignLi J, Dreyer R, Li X, Du X, Downing N, Li L, Feng F, Zhang H, Zhan L, Guan W, Xu X, Li S, Lin Z, Masoudi F, Spertus J, Krumholz H, Jiang L. Abstract 278: The China Patient-Centered Evaluative Assessment of Cardiac Events (PEACE) Prospective Study of Acute Myocardial Infarction: Study Design. Circulation Cardiovascular Quality And Outcomes 2015, 8 DOI: 10.1161/circoutcomes.8.suppl_2.278.
Association Between Journal Citation Distribution and Impact Factor A Novel Application of the Gini CoefficientNuti SV, Ranasinghe I, Murugiah K, Shojaee A, Li SX, Krumholz HM. Association Between Journal Citation Distribution and Impact Factor A Novel Application of the Gini Coefficient. Journal Of The American College Of Cardiology 2015, 65: 1711-1712. PMID: 25908079, PMCID: PMC5459371, DOI: 10.1016/j.jacc.2014.12.071.
Intravenous Fluids in Acute Decompensated Heart FailureBikdeli B, Strait KM, Dharmarajan K, Li SX, Mody P, Partovian C, Coca SG, Kim N, Horwitz LI, Testani JM, Krumholz HM. Intravenous Fluids in Acute Decompensated Heart Failure. JACC Heart Failure 2015, 3: 127-133. PMID: 25660836, PMCID: PMC4438991, DOI: 10.1016/j.jchf.2014.09.007.
Abstract 20172: Identifying Hospital Cardiac Services for Acute Myocardial Infarction Using Individual Patient Claims DataChang T, Li S, Ranasinghe I, Krumholz H. Abstract 20172: Identifying Hospital Cardiac Services for Acute Myocardial Infarction Using Individual Patient Claims Data. Circulation 2014, 130 DOI: 10.1161/circ.130.suppl_2.20172.
“Phenotyping” Hospital Value of Care for Patients with Heart FailureXu X, Li S, Lin H, Normand S, Kim N, Ott LS, Lagu T, Duan M, Kroch EA, Krumholz HM. “Phenotyping” Hospital Value of Care for Patients with Heart Failure. Health Services Research 2014, 49: 2000-2016. PMID: 24974769, PMCID: PMC4254136, DOI: 10.1111/1475-6773.12197.
National Patterns of Risk-Standardized Mortality and Readmission After Hospitalization for Acute Myocardial Infarction, Heart Failure, and Pneumonia: Update on Publicly Reported Outcomes Measures Based on the 2013 ReleaseSuter LG, Li SX, Grady JN, Lin Z, Wang Y, Bhat KR, Turkmani D, Spivack SB, Lindenauer PK, Merrill AR, Drye EE, Krumholz HM, Bernheim SM. National Patterns of Risk-Standardized Mortality and Readmission After Hospitalization for Acute Myocardial Infarction, Heart Failure, and Pneumonia: Update on Publicly Reported Outcomes Measures Based on the 2013 Release. Journal Of General Internal Medicine 2014, 29: 1333-1340. PMID: 24825244, PMCID: PMC4175654, DOI: 10.1007/s11606-014-2862-5.
Hospital Variation in the Use of Noninvasive Cardiac Imaging and Its Association With Downstream Testing, Interventions, and OutcomesSafavi KC, Li SX, Dharmarajan K, Venkatesh AK, Strait KM, Lin H, Lowe TJ, Fazel R, Nallamothu BK, Krumholz HM. Hospital Variation in the Use of Noninvasive Cardiac Imaging and Its Association With Downstream Testing, Interventions, and Outcomes. JAMA Internal Medicine 2014, 174: 546-553. PMID: 24515551, PMCID: PMC5459406, DOI: 10.1001/jamainternmed.2013.14407.
Hospital Variation in Intravenous Inotrope Use for Patients Hospitalized With Heart FailureAllen LA, Fonarow GC, Grau-Sepulveda MV, Hernandez AF, Peterson PN, Partovian C, Li SX, Heidenreich PA, Bhatt DL, Peterson ED, Krumholz HM. Hospital Variation in Intravenous Inotrope Use for Patients Hospitalized With Heart Failure. Circulation Heart Failure 2014, 7: 251-260. PMID: 24488983, PMCID: PMC5459367, DOI: 10.1161/circheartfailure.113.000761.
Acute Decompensated Heart Failure Is Routinely Treated as a Cardiopulmonary SyndromeDharmarajan K, Strait KM, Lagu T, Lindenauer PK, Tinetti ME, Lynn J, Li SX, Krumholz HM. Acute Decompensated Heart Failure Is Routinely Treated as a Cardiopulmonary Syndrome. PLOS ONE 2013, 8: e78222. PMID: 24250751, PMCID: PMC3824040, DOI: 10.1371/journal.pone.0078222.
Contraindicated Initiation of β-Blocker Therapy in Patients Hospitalized for Heart FailureDharmarajan K, Masoudi FA, Spertus JA, Li SX, Krumholz HM. Contraindicated Initiation of β-Blocker Therapy in Patients Hospitalized for Heart Failure. JAMA Internal Medicine 2013, 173: 1547-1549. PMID: 23797379, PMCID: PMC4043342, DOI: 10.1001/jamainternmed.2013.7717.
Patterns of Change in Nesiritide Use in Patients With Heart Failure How Hospitals React to New InformationPartovian C, Li SX, Xu X, Lin H, Strait KM, Hwa J, Krumholz HM. Patterns of Change in Nesiritide Use in Patients With Heart Failure How Hospitals React to New Information. JACC Heart Failure 2013, 1: 318-324. PMID: 24621935, PMCID: PMC5322944, DOI: 10.1016/j.jchf.2013.04.005.
Spending more, doing more, or both? An alternative method for quantifying utilization during hospitalizationsLagu T, Krumholz HM, Dharmarajan K, Partovian C, Kim N, Mody PS, Li S, Strait KM, Lindenauer PK. Spending more, doing more, or both? An alternative method for quantifying utilization during hospitalizations. Journal Of Hospital Medicine 2013, 8: 373-379. PMID: 23757115, PMCID: PMC4014449, DOI: 10.1002/jhm.2046.
Abstract 325: Acute Decompensated Heart Failure, Pneumonia, and Exacerbated Chronic Obstructive Pulmonary Disease are all Routinely Treated as Cardiopulmonary SyndromesDharmarajan K, Strait K, Lagu T, Lindenauer P, Tinetti M, Lynn J, Li S, Krumholz H. Abstract 325: Acute Decompensated Heart Failure, Pneumonia, and Exacerbated Chronic Obstructive Pulmonary Disease are all Routinely Treated as Cardiopulmonary Syndromes. Circulation Cardiovascular Quality And Outcomes 2013, 6 DOI: 10.1161/circoutcomes.6.suppl_1.a325.
Abstract 345: Hospital Variation in Admission to Intensive Care Units for Patients with Acute Myocardial InfarctionChen R, Strait K, Dharmarajan K, Li S, Martin J, Masoudi F, Cooke C, Nallamothu B, Krumholz H. Abstract 345: Hospital Variation in Admission to Intensive Care Units for Patients with Acute Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2013, 6 DOI: 10.1161/circoutcomes.6.suppl_1.a345.
Dominance of Furosemide for Loop Diuretic Therapy in Heart Failure Time to Revisit the Alternatives?Bikdeli B, Strait KM, Dharmarajan K, Partovian C, Coca SG, Kim N, Li SX, Testani JM, Khan U, Krumholz HM. Dominance of Furosemide for Loop Diuretic Therapy in Heart Failure Time to Revisit the Alternatives? Journal Of The American College Of Cardiology 2013, 61: 1549-1550. PMID: 23500272, PMCID: PMC4038646, DOI: 10.1016/j.jacc.2012.12.043.
Variation Exists in Rates of Admission to Intensive Care Units for Heart Failure Patients Across Hospitals in the United StatesSafavi KC, Dharmarajan K, Kim N, Strait KM, Li SX, Chen SI, Lagu T, Krumholz HM. Variation Exists in Rates of Admission to Intensive Care Units for Heart Failure Patients Across Hospitals in the United States. Circulation 2013, 127: 923-929. PMID: 23355624, PMCID: PMC3688061, DOI: 10.1161/circulationaha.112.001088.
Hospital Patterns of Use of Positive Inotropic Agents in Patients With Heart FailurePartovian C, Gleim SR, Mody PS, Li SX, Wang H, Strait KM, Allen LA, Lagu T, Normand SL, Krumholz HM. Hospital Patterns of Use of Positive Inotropic Agents in Patients With Heart Failure. Journal Of The American College Of Cardiology 2012, 60: 1402-1409. PMID: 22981548, PMCID: PMC3636773, DOI: 10.1016/j.jacc.2012.07.011.
Procedure Intensity and the Cost of CareChen SI, Dharmarajan K, Kim N, Strait KM, Li SX, Safavi KC, Lindenauer PK, Krumholz HM, Lagu T. Procedure Intensity and the Cost of Care. Circulation Cardiovascular Quality And Outcomes 2012, 5: 308-313. PMID: 22576844, PMCID: PMC3415230, DOI: 10.1161/circoutcomes.112.966069.
Abstract 236: Complex Patients: The Majority Hospitalized with Heart Failure also Receive Treatment for Acute Respiratory ConditionsDharmarajan K, Strait K, Lagu T, Li S, Lynn J, Lindenauer P, Tinetti M, Krumholz H. Abstract 236: Complex Patients: The Majority Hospitalized with Heart Failure also Receive Treatment for Acute Respiratory Conditions. Circulation Cardiovascular Quality And Outcomes 2012, 5 DOI: 10.1161/circoutcomes.5.suppl_1.a236.
Abstract 114: Common Diagnostic Tests Do Not Guide Treatment for Acute Respiratory Conditions in Patients Hospitalized with Heart FailureDharmarajan K, Strait K, Lagu T, Li S, Krumholz H. Abstract 114: Common Diagnostic Tests Do Not Guide Treatment for Acute Respiratory Conditions in Patients Hospitalized with Heart Failure. Circulation Cardiovascular Quality And Outcomes 2012, 5 DOI: 10.1161/circoutcomes.5.suppl_1.a114.
Abstract 222: Administration of Intravenous Fluids in Patients Hospitalized with Heart FailureMody P, Li S, Dharmarajan K, Kim N, Strait K, Horwitz L, Krumholz H. Abstract 222: Administration of Intravenous Fluids in Patients Hospitalized with Heart Failure. Circulation Cardiovascular Quality And Outcomes 2012, 5 DOI: 10.1161/circoutcomes.5.suppl_1.a222.
Abstract 2: Cost of Care for Heart Failure Patients Varies Substantially Among Hospitals Even When Controlling for Procedure UseChen S, Strait K, Dharmarajan K, Li S, Kim N, Safavi K, Lagu T, Krumholz H. Abstract 2: Cost of Care for Heart Failure Patients Varies Substantially Among Hospitals Even When Controlling for Procedure Use. Circulation Cardiovascular Quality And Outcomes 2012, 5 DOI: 10.1161/circoutcomes.5.suppl_1.a2.
Abstract 187: Loop Diuretic Therapy in Acute Decompensated Heart Failure among Premier HospitalsBikdeli B, Strait K, Dharmarajan K, Partovian C, Kim N, Li S, Krumholz H. Abstract 187: Loop Diuretic Therapy in Acute Decompensated Heart Failure among Premier Hospitals. Circulation Cardiovascular Quality And Outcomes 2012, 5 DOI: 10.1161/circoutcomes.5.suppl_1.a187.
WIDE VARIATION EXISTS IN RATES OF ADMISSION TO INTENSIVE CARE UNITS FOR HEART FAILURE PATIENTS ACROSS US HOSPITALSSafavi K, Dharmarajan K, Kim N, Strait K, Li S, Chen S, Lagu T, Partovian C, Krumholz H. WIDE VARIATION EXISTS IN RATES OF ADMISSION TO INTENSIVE CARE UNITS FOR HEART FAILURE PATIENTS ACROSS US HOSPITALS. Journal Of The American College Of Cardiology 2012, 59: e1856. DOI: 10.1016/s0735-1097(12)61857-9.
Long-term Trends in Short-term Outcomes in Acute Myocardial InfarctionNguyen HL, Saczynski JS, Gore JM, Waring ME, Lessard D, Yarzebski J, Reed G, Spencer FA, Li SX, Goldberg RJ. Long-term Trends in Short-term Outcomes in Acute Myocardial Infarction. The American Journal Of Medicine 2011, 124: 939-946. PMID: 21962314, PMCID: PMC3185241, DOI: 10.1016/j.amjmed.2011.05.023.
DNA repair and personalized breast cancer therapyLi S, Sjolund A, Harris L, Sweasy JB. DNA repair and personalized breast cancer therapy. Environmental And Molecular Mutagenesis 2010, 51: 897-908. PMID: 20872853, PMCID: PMC2962983, DOI: 10.1002/em.20606.
Changes in gene expression predicting local control in cervical cancer: results from Radiation Therapy Oncology Group 0128.Weidhaas JB, Li SX, Winter K, Ryu J, Jhingran A, Miller B, Dicker AP, Gaffney D. Changes in gene expression predicting local control in cervical cancer: results from Radiation Therapy Oncology Group 0128. Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research 2009, 15: 4199-206. PMID: 19509178, PMCID: PMC2758917, DOI: 10.1158/1078-0432.CCR-08-2257.
A DNA polymerase β mutant from colon cancer cells induces mutationsLang T, Maitra M, Starcevic D, Li SX, Sweasy JB. A DNA polymerase β mutant from colon cancer cells induces mutations. Proceedings Of The National Academy Of Sciences Of The United States Of America 2004, 101: 6074-6079. PMID: 15075389, PMCID: PMC395925, DOI: 10.1073/pnas.0308571101.
Threonine 79 Is a Hinge Residue That Governs the Fidelity of DNA Polymerase β by Helping to Position the DNA within the Active Site*Maitra M, Gudzelak A, Li SX, Matsumoto Y, Eckert KA, Jager J, Sweasy JB. Threonine 79 Is a Hinge Residue That Governs the Fidelity of DNA Polymerase β by Helping to Position the DNA within the Active Site*. Journal Of Biological Chemistry 2002, 277: 35550-35560. PMID: 12121998, DOI: 10.1074/jbc.m204953200.
A DNA Polymerase β Mutator Mutant with Reduced Nucleotide Discrimination and Increased Protein Stability † , ‡Shah A, Conn D, Li S, Capaldi A, Jäger J, Sweasy J. A DNA Polymerase β Mutator Mutant with Reduced Nucleotide Discrimination and Increased Protein Stability † , ‡. Biochemistry 2001, 40: 11372-11381. PMID: 11560485, DOI: 10.1021/bi010755y.
Y265H Mutator Mutant of DNA Polymerase β PROPER GEOMETRIC ALIGNMENT IS CRITICAL FOR FIDELITY*Shah A, Li S, Anderson K, Sweasy J. Y265H Mutator Mutant of DNA Polymerase β PROPER GEOMETRIC ALIGNMENT IS CRITICAL FOR FIDELITY*. Journal Of Biological Chemistry 2001, 276: 10824-10831. PMID: 11154692, DOI: 10.1074/jbc.m008680200.
Involvement of Phenylalanine 272 of DNA Polymerase Beta in Discriminating between Correct and Incorrect Deoxynucleoside Triphosphates †Li S, Vaccaro J, Sweasy J. Involvement of Phenylalanine 272 of DNA Polymerase Beta in Discriminating between Correct and Incorrect Deoxynucleoside Triphosphates †. Biochemistry 1999, 38: 4800-4808. PMID: 10200168, DOI: 10.1021/bi9827058.
A genetic system to identify DNA polymerase β mutator mutantsWashington S, Yoon M, Chagovetz A, Li S, Clairmont C, Preston B, Eckert K, Sweasy J. A genetic system to identify DNA polymerase β mutator mutants. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 1321-1326. PMID: 9037051, PMCID: PMC19789, DOI: 10.1073/pnas.94.4.1321.

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