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Kumar Dharmarajan, MD, MBA

Assistant Professor Adjunct

Research & Publications
Biography
News

Research Summary

Dr. Dharmarajan's primary interests have been in improving health outcomes for older persons, including those with cardiovascular disease. His research has made fundamental contributions to understanding the vulnerability experienced by patients after hospitalization as well as important ways in which hospitals and health systems can help patients avoid rehospitalization.

Coauthors

Research Interests

Cardiology; Geriatrics; Quality of Health Care; Hospital Medicine

Public Health Interests

Health Care Quality, Efficiency; Health Policy

Selected Publications

Disability and Recovery After Hospitalization for Medical Illness Among Community‐Living Older Persons: A Prospective Cohort StudyDharmarajan K, Han L, Gahbauer EA, Leo‐Summers L, Gill TM. Disability and Recovery After Hospitalization for Medical Illness Among Community‐Living Older Persons: A Prospective Cohort Study Journal Of The American Geriatrics Society 2020, 68: 486-495. PMID: 32083319, PMCID: PMC7735402, DOI: 10.1111/jgs.16350.
Modeling defibrillation benefit for survival among cardiac resynchronization therapy defibrillator recipientsBilchick KC, Wang Y, Curtis JP, Cheng A, Dharmarajan K, Shadman R, Dardas TF, Anand I, Lund LH, Dahlström U, Sartipy U, Maggioni A, O'Connor C, Levy WC. Modeling defibrillation benefit for survival among cardiac resynchronization therapy defibrillator recipients American Heart Journal 2019, 222: 93-104. PMID: 32032927, PMCID: PMC7814502, DOI: 10.1016/j.ahj.2019.12.017.
Home Health Care After Skilled Nursing Facility Discharge Following Heart Failure HospitalizationWeerahandi H, Bao H, Herrin J, Dharmarajan K, Ross JS, Jones S, Horwitz LI. Home Health Care After Skilled Nursing Facility Discharge Following Heart Failure Hospitalization Journal Of The American Geriatrics Society 2019, 68: 96-102. PMID: 31603248, PMCID: PMC6964248, DOI: 10.1111/jgs.16179.
Post Hospital Syndrome: Is the Stress of Hospitalization Causing Harm?Caraballo C, Dharmarajan K, Krumholz HM. Post Hospital Syndrome: Is the Stress of Hospitalization Causing Harm? Revista Española De Cardiología (English Edition) 2019, 72: 896-898. PMID: 31175070, DOI: 10.1016/j.rec.2019.04.010.
Association Between Insurance Status and Access to Hospital Care in Emergency Department DispositionVenkatesh AK, Chou SC, Li SX, Choi J, Ross JS, D’Onofrio G, Krumholz HM, Dharmarajan K. Association Between Insurance Status and Access to Hospital Care in Emergency Department Disposition JAMA Internal Medicine 2019, 179: 686-693. PMID: 30933243, PMCID: PMC6503571, DOI: 10.1001/jamainternmed.2019.0037.
Thirty-Day Hospital Readmission After Acute Myocardial Infarction in ChinaLi J, Dharmarajan K, Bai X, Masoudi FA, Spertus JA, Li X, Zheng X, Zhang H, Yan X, Dreyer RP, Krumholz HM, Group F. Thirty-Day Hospital Readmission After Acute Myocardial Infarction in China Circulation Cardiovascular Quality And Outcomes 2019, 12: e005628. PMID: 31092023, DOI: 10.1161/circoutcomes.119.005628.
Risk of Readmission After Discharge From Skilled Nursing Facilities Following Heart Failure Hospitalization: A Retrospective Cohort StudyWeerahandi H, Li L, Bao H, Herrin J, Dharmarajan K, Ross JS, Kim KL, Jones S, Horwitz LI. Risk of Readmission After Discharge From Skilled Nursing Facilities Following Heart Failure Hospitalization: A Retrospective Cohort Study Journal Of The American Medical Directors Association 2019, 20: 432-437. PMID: 30954133, PMCID: PMC6486375, DOI: 10.1016/j.jamda.2019.01.135.
Trends in Performance and Opportunities for Improvement on a Composite Measure of Acute Myocardial Infarction CareDesai NR, Udell JA, Wang Y, Spatz ES, Dharmarajan K, Ahmad T, Julien HM, Annapureddy A, Goyal A, de Lemos JA, Masoudi FA, Bhatt DL, Minges KE, Krumholz HM, Curtis JP. Trends in Performance and Opportunities for Improvement on a Composite Measure of Acute Myocardial Infarction Care Circulation Cardiovascular Quality And Outcomes 2019, 12: e004983. PMID: 30871375, DOI: 10.1161/circoutcomes.118.004983.
Association of Income Disparities with Patient-Reported Healthcare ExperienceOkunrintemi V, Khera R, Spatz ES, Salami JA, Valero-Elizondo J, Warraich HJ, Virani SS, Blankstein R, Blaha MJ, Pawlik TM, Dharmarajan K, Krumholz HM, Nasir K. Association of Income Disparities with Patient-Reported Healthcare Experience Journal Of General Internal Medicine 2019, 34: 884-892. PMID: 30783877, PMCID: PMC6544715, DOI: 10.1007/s11606-019-04848-4.
Relationship Between Patient-Reported Hospital Experience and 30-Day Mortality and Readmission Rates for Acute Myocardial Infarction, Heart Failure, and PneumoniaDong N, Eisenberg JD, Dharmarajan K, Spatz ES, Desai NR. Relationship Between Patient-Reported Hospital Experience and 30-Day Mortality and Readmission Rates for Acute Myocardial Infarction, Heart Failure, and Pneumonia Journal Of General Internal Medicine 2019, 34: 526-528. PMID: 30746641, PMCID: PMC6446004, DOI: 10.1007/s11606-018-4746-6.
Assessment of Instruments for Measurement of Delirium SeverityJones RN, Cizginer S, Pavlech L, Albuquerque A, Daiello LA, Dharmarajan K, Gleason LJ, Helfand B, Massimo L, Oh E, Okereke OI, Tabloski P, Rabin LA, Yue J, Marcantonio ER, Fong TG, Hshieh TT, Metzger ED, Erickson K, Schmitt EM, Inouye SK. Assessment of Instruments for Measurement of Delirium Severity JAMA Internal Medicine 2019, 179: 231-239. PMID: 30556827, PMCID: PMC6382582, DOI: 10.1001/jamainternmed.2018.6975.
Admission diagnoses among patients with heart failure: Variation by ACO performance on a measure of risk-standardized acute admission ratesBenchetrit L, Zimmerman C, Bao H, Dharmarajan K, Altaf F, Herrin J, Lin Z, Krumholz HM, Drye EE, Lipska KJ, Spatz ES. Admission diagnoses among patients with heart failure: Variation by ACO performance on a measure of risk-standardized acute admission rates American Heart Journal 2018, 207: 19-26. PMID: 30404047, DOI: 10.1016/j.ahj.2018.09.006.
Trends in 30-Day Readmission Rates for Medicare and Non-Medicare Patients in the Era of the Affordable Care ActAngraal S, Khera R, Zhou S, Wang Y, Lin Z, Dharmarajan K, Desai NR, Bernheim SM, Drye EE, Nasir K, Horwitz LI, Krumholz HM. Trends in 30-Day Readmission Rates for Medicare and Non-Medicare Patients in the Era of the Affordable Care Act The American Journal Of Medicine 2018, 131: 1324-1331.e14. PMID: 30016636, PMCID: PMC6380174, DOI: 10.1016/j.amjmed.2018.06.013.
Association of the Hospital Readmissions Reduction Program With Mortality During and After Hospitalization for Acute Myocardial Infarction, Heart Failure, and PneumoniaKhera R, Dharmarajan K, Wang Y, Lin Z, Bernheim SM, Wang Y, Normand ST, Krumholz HM. Association of the Hospital Readmissions Reduction Program With Mortality During and After Hospitalization for Acute Myocardial Infarction, Heart Failure, and Pneumonia JAMA Network Open 2018, 1: e182777. PMID: 30646181, PMCID: PMC6324473, DOI: 10.1001/jamanetworkopen.2018.2777.
Rising Mortality in Patients With Heart Failure in the United States Facts Versus FictionKhera R, Dharmarajan K, Krumholz HM. Rising Mortality in Patients With Heart Failure in the United States Facts Versus Fiction JACC Heart Failure 2018, 6: 610-612. PMID: 29914774, DOI: 10.1016/j.jchf.2018.02.011.
Is Posthospital Syndrome a Result of Hospitalization-Induced Allostatic Overload?Goldwater DS, Dharmarajan K, McEwan BS, Krumholz HM. Is Posthospital Syndrome a Result of Hospitalization-Induced Allostatic Overload? Journal Of Hospital Medicine 2018, 13 PMID: 29813141, DOI: 10.12788/jhm.2986.
Reply to Soo Hoo and Esquinas: Risk Trajectories of Readmission and Death in the First Year after Hospitalization for Chronic Obstructive Pulmonary Disease: Don’t Shortchange Noninvasive VentilationLindenauer PK, Dharmarajan K, Krumholz HM. Reply to Soo Hoo and Esquinas: Risk Trajectories of Readmission and Death in the First Year after Hospitalization for Chronic Obstructive Pulmonary Disease: Don’t Shortchange Noninvasive Ventilation American Journal Of Respiratory And Critical Care Medicine 2018, 198: 283-284. PMID: 29566340, PMCID: PMC6058983, DOI: 10.1164/rccm.201803-0426le.
Evaluating Readmission—Need for More Clarity on MethodsKrumholz HM, Dharmarajan K, Normand ST. Evaluating Readmission—Need for More Clarity on Methods JAMA Cardiology 2018, 3: 265. PMID: 29450464, DOI: 10.1001/jamacardio.2017.5321.
Risk Trajectories of Readmission and Death in the First Year after Hospitalization for Chronic Obstructive Pulmonary DiseaseLindenauer PK, Dharmarajan K, Qin L, Lin Z, Gershon AS, Krumholz HM. Risk Trajectories of Readmission and Death in the First Year after Hospitalization for Chronic Obstructive Pulmonary Disease American Journal Of Respiratory And Critical Care Medicine 2017, 197: 1009-1017. PMID: 29206052, PMCID: PMC5909167, DOI: 10.1164/rccm.201709-1852oc.
Consequences of Reductions in Hospital Readmissions—ReplyDharmarajan K, Krumholz HM. Consequences of Reductions in Hospital Readmissions—Reply JAMA 2017, 318: 1934-1934. PMID: 29164250, DOI: 10.1001/jama.2017.14799.
Age Differences in Hospital Mortality for Acute Myocardial Infarction: Implications for Hospital Profiling.Dharmarajan K, McNamara RL, Wang Y, Masoudi FA, Ross JS, Spatz EE, Desai NR, de Lemos JA, Fonarow GC, Heidenreich PA, Bhatt DL, Bernheim SM, Slattery LE, Khan YM, Curtis JP. Age Differences in Hospital Mortality for Acute Myocardial Infarction: Implications for Hospital Profiling. Annals Of Internal Medicine 2017, 167: 555-564. PMID: 28973634, PMCID: PMC9359429, DOI: 10.7326/m16-2871.
Hospital-Readmission Risk — Isolating Hospital Effects from Patient EffectsKrumholz HM, Wang K, Lin Z, Dharmarajan K, Horwitz LI, Ross JS, Drye EE, Bernheim SM, Normand ST. Hospital-Readmission Risk — Isolating Hospital Effects from Patient Effects New England Journal Of Medicine 2017, 377: 1055-1064. PMID: 28902587, PMCID: PMC5671772, DOI: 10.1056/nejmsa1702321.
Predicting death after acute myocardial infarctionCastro-Dominguez Y, Dharmarajan K, McNamara RL. Predicting death after acute myocardial infarction Trends In Cardiovascular Medicine 2017, 28: 102-109. PMID: 28826668, DOI: 10.1016/j.tcm.2017.07.011.
Length of Stay From the Hospital PerspectiveRosen JE, Salazar MC, Dharmarajan K, Kim AW, Detterbeck FC, Boffa DJ. Length of Stay From the Hospital Perspective Annals Of Surgery 2017, 266: 383-388. PMID: 27564681, DOI: 10.1097/sla.0000000000001971.
Regional variation in hospitalisation and mortality in heart failure: comparison of England and Lombardy using multistate modellingBottle A, Ventura CM, Dharmarajan K, Aylin P, Ieva F, Paganoni AM. Regional variation in hospitalisation and mortality in heart failure: comparison of England and Lombardy using multistate modelling Health Care Management Science 2017, 21: 292-304. PMID: 28755175, DOI: 10.1007/s10729-017-9410-x.
Reductions in Readmission Rates Are Associated With Modest Improvements in Patient-reported Health Gains Following Hip and Knee Replacement in EnglandFriebel R, Dharmarajan K, Krumholz HM, Steventon A. Reductions in Readmission Rates Are Associated With Modest Improvements in Patient-reported Health Gains Following Hip and Knee Replacement in England Medical Care 2017, 55: 834-840. PMID: 28742545, PMCID: PMC5555974, DOI: 10.1097/mlr.0000000000000779.
Association of Changing Hospital Readmission Rates With Mortality Rates After Hospital DischargeDharmarajan K, Wang Y, Lin Z, Normand ST, Ross JS, Horwitz LI, Desai NR, Suter LG, Drye EE, Bernheim SM, Krumholz HM. Association of Changing Hospital Readmission Rates With Mortality Rates After Hospital Discharge JAMA 2017, 318: 270-278. PMID: 28719692, PMCID: PMC5817448, DOI: 10.1001/jama.2017.8444.
Epidemiology, Pathophysiology, and Prognosis of Heart Failure in Older AdultsDharmarajan K, Rich MW. Epidemiology, Pathophysiology, and Prognosis of Heart Failure in Older Adults Heart Failure Clinics 2017, 13: 417-426. PMID: 28602363, DOI: 10.1016/j.hfc.2017.02.001.
Quality of Care in Chinese Hospitals: Processes and Outcomes After ST‐segment Elevation Myocardial InfarctionDowning NS, Wang Y, Dharmarajan K, Nuti SV, Murugiah K, Du X, Zheng X, Li X, Li J, Masoudi FA, Spertus JA, Jiang L, Krumholz HM. Quality of Care in Chinese Hospitals: Processes and Outcomes After ST‐segment Elevation Myocardial Infarction Journal Of The American Heart Association 2017, 6: e005040. PMID: 28645937, PMCID: PMC5669155, DOI: 10.1161/jaha.116.005040.
Outcomes after observation stays among older adult Medicare beneficiaries in the USA: retrospective cohort studyDharmarajan K, Qin L, Bierlein M, Choi JES, Lin Z, Desai NR, Spatz ES, Krumholz HM, Venkatesh AK. Outcomes after observation stays among older adult Medicare beneficiaries in the USA: retrospective cohort study The BMJ 2017, 357: j2616. PMID: 28634181, PMCID: PMC5476173, DOI: 10.1136/bmj.j2616.
Seattle Heart Failure and Proportional Risk Models Predict Benefit From Implantable Cardioverter-DefibrillatorsBilchick KC, Wang Y, Cheng A, Curtis JP, Dharmarajan K, Stukenborg GJ, Shadman R, Anand I, Lund LH, Dahlström U, Sartipy U, Maggioni A, Swedberg K, O’Conner C, Levy WC. Seattle Heart Failure and Proportional Risk Models Predict Benefit From Implantable Cardioverter-Defibrillators Journal Of The American College Of Cardiology 2017, 69: 2606-2618. PMID: 28545633, PMCID: PMC5502749, DOI: 10.1016/j.jacc.2017.03.568.
Sex Differences in Trajectories of Risk After Rehospitalization for Heart Failure, Acute Myocardial Infarction, or PneumoniaDreyer RP, Dharmarajan K, Hsieh AF, Welsh J, Qin L, Krumholz HM. Sex Differences in Trajectories of Risk After Rehospitalization for Heart Failure, Acute Myocardial Infarction, or Pneumonia Circulation Cardiovascular Quality And Outcomes 2017, 10: e003271. PMID: 28506980, PMCID: PMC5650228, DOI: 10.1161/circoutcomes.116.003271.
The medically managed patient with severe symptomatic aortic stenosis in the TAVR era: Patient characteristics, reasons for medical management, and quality of shared decision making at heart valve treatment centersDharmarajan K, Foster J, Coylewright M, Green P, Vavalle JP, Faheem O, Huang PH, Krishnaswamy A, Thourani VH, McCoy LA, Wang TY. The medically managed patient with severe symptomatic aortic stenosis in the TAVR era: Patient characteristics, reasons for medical management, and quality of shared decision making at heart valve treatment centers PLOS ONE 2017, 12: e0175926. PMID: 28430791, PMCID: PMC5400246, DOI: 10.1371/journal.pone.0175926.
Patient–Provider Communication and Health Outcomes Among Individuals With Atherosclerotic Cardiovascular Disease in the United StatesOkunrintemi V, Spatz ES, Di Capua P, Salami JA, Valero-Elizondo J, Warraich H, Virani SS, Blaha MJ, Blankstein R, Butt AA, Borden WB, Dharmarajan K, Ting H, Krumholz HM, Nasir K. Patient–Provider Communication and Health Outcomes Among Individuals With Atherosclerotic Cardiovascular Disease in the United States Circulation Cardiovascular Quality And Outcomes 2017, 10: e003635. PMID: 28373270, DOI: 10.1161/circoutcomes.117.003635.
Sex Differences in 1-Year All-Cause Rehospitalization in Patients After Acute Myocardial InfarctionDreyer RP, Dharmarajan K, Kennedy KF, Jones PG, Vaccarino V, Murugiah K, Nuti SV, Smolderen KG, Buchanan DM, Spertus JA, Krumholz HM. Sex Differences in 1-Year All-Cause Rehospitalization in Patients After Acute Myocardial Infarction Circulation 2017, 135: 521-531. PMID: 28153989, PMCID: PMC5312975, DOI: 10.1161/circulationaha.116.024993.
Hospitals’ Role In ReadmissionsDharmarajan K, Lin Z, Normand ST. Hospitals’ Role In Readmissions Health Affairs 2017, 36: 382.1-382. PMID: 28167732, DOI: 10.1377/hlthaff.2016.1515.
Pathway from Delirium to Death: Potential In‐Hospital Mediators of Excess MortalityDharmarajan K, Swami S, Gou RY, Jones RN, Inouye SK. Pathway from Delirium to Death: Potential In‐Hospital Mediators of Excess Mortality Journal Of The American Geriatrics Society 2016, 65: 1026-1033. PMID: 28039852, PMCID: PMC5435507, DOI: 10.1111/jgs.14743.
Association Between Hospital Penalty Status Under the Hospital Readmission Reduction Program and Readmission Rates for Target and Nontarget ConditionsDesai NR, Ross JS, Kwon JY, Herrin J, Dharmarajan K, Bernheim SM, Krumholz HM, Horwitz LI. Association Between Hospital Penalty Status Under the Hospital Readmission Reduction Program and Readmission Rates for Target and Nontarget Conditions JAMA 2016, 316: 2647-2656. PMID: 28027367, PMCID: PMC5599851, DOI: 10.1001/jama.2016.18533.
Relationship Between Age and Trajectories of Rehospitalization Risk in Older AdultsDharmarajan K, Hsieh A, Dreyer RP, Welsh J, Qin L, Krumholz HM. Relationship Between Age and Trajectories of Rehospitalization Risk in Older Adults Journal Of The American Geriatrics Society 2016, 65: 421-426. PMID: 27874977, PMCID: PMC5310961, DOI: 10.1111/jgs.14583.
Analysis of Machine Learning Techniques for Heart Failure ReadmissionsMortazavi BJ, Downing NS, Bucholz EM, Dharmarajan K, Manhapra A, Li SX, Negahban SN, Krumholz HM. Analysis of Machine Learning Techniques for Heart Failure Readmissions Circulation Cardiovascular Quality And Outcomes 2016, 9: 629-640. PMID: 28263938, PMCID: PMC5459389, DOI: 10.1161/circoutcomes.116.003039.
Trajectories of Risk for Specific Readmission Diagnoses after Hospitalization for Heart Failure, Acute Myocardial Infarction, or PneumoniaKrumholz HM, Hsieh A, Dreyer RP, Welsh J, Desai NR, Dharmarajan K. Trajectories of Risk for Specific Readmission Diagnoses after Hospitalization for Heart Failure, Acute Myocardial Infarction, or Pneumonia PLOS ONE 2016, 11: e0160492. PMID: 27716841, PMCID: PMC5055318, DOI: 10.1371/journal.pone.0160492.
What Can Geriatrics Teach Cardiology?Dharmarajan K. What Can Geriatrics Teach Cardiology? Current Cardiovascular Risk Reports 2016, 10: 34. PMID: 28729895, PMCID: PMC5513184, DOI: 10.1007/s12170-016-0516-3.
Impact of Exercise Programs on Hospital Readmission Following Hospitalization for Heart Failure: A Systematic ReviewGoyal P, Delgado D, Hummel SL, Dharmarajan K. Impact of Exercise Programs on Hospital Readmission Following Hospitalization for Heart Failure: A Systematic Review Current Cardiovascular Risk Reports 2016, 10: 33. PMID: 28713480, PMCID: PMC5507625, DOI: 10.1007/s12170-016-0514-5.
Treatment for Multiple Acute Cardiopulmonary Conditions in Older Adults Hospitalized with Pneumonia, Chronic Obstructive Pulmonary Disease, or Heart FailureDharmarajan K, Strait KM, Tinetti ME, Lagu T, Lindenauer PK, Lynn J, Krukas MR, Ernst FR, Li SX, Krumholz HM. Treatment for Multiple Acute Cardiopulmonary Conditions in Older Adults Hospitalized with Pneumonia, Chronic Obstructive Pulmonary Disease, or Heart Failure Journal Of The American Geriatrics Society 2016, 64: 1574-1582. PMID: 27448329, PMCID: PMC4988873, DOI: 10.1111/jgs.14303.
Declining Admission Rates And Thirty-Day Readmission Rates Positively Associated Even Though Patients Grew Sicker Over TimeDharmarajan K, Qin L, Lin Z, Horwitz LI, Ross JS, Drye EE, Keshawarz A, Altaf F, Normand SL, Krumholz HM, Bernheim SM. Declining Admission Rates And Thirty-Day Readmission Rates Positively Associated Even Though Patients Grew Sicker Over Time Health Affairs 2016, 35: 1294-1302. PMID: 27385247, DOI: 10.1377/hlthaff.2015.1614.
Outcomes 1 Year After Implantable Cardioverter–Defibrillator Lead Abandonment Versus Explantation for Unused or Malfunctioning LeadsZeitler EP, Wang Y, Dharmarajan K, Anstrom KJ, Peterson ED, Daubert JP, Curtis JP, Al-Khatib SM. Outcomes 1 Year After Implantable Cardioverter–Defibrillator Lead Abandonment Versus Explantation for Unused or Malfunctioning Leads Circulation Arrhythmia And Electrophysiology 2016, 9: e003953. PMID: 27406605, PMCID: PMC4973616, DOI: 10.1161/circep.116.003953.
Coronary Catheterization and Percutaneous Coronary Intervention in China: 10-Year Results From the China PEACE-Retrospective CathPCI StudyZheng X, Curtis JP, Hu S, Wang Y, Yang Y, Masoudi FA, Spertus JA, Li X, Li J, Dharmarajan K, Downing NS, Krumholz HM, Jiang L. Coronary Catheterization and Percutaneous Coronary Intervention in China: 10-Year Results From the China PEACE-Retrospective CathPCI Study JAMA Internal Medicine 2016, 176: 512. PMID: 26974883, PMCID: PMC5459379, DOI: 10.1001/jamainternmed.2016.0166.
New Approaches to Reduce Readmissions in Patients With Heart FailureDharmarajan K, Chaudhry SI. New Approaches to Reduce Readmissions in Patients With Heart Failure JAMA Internal Medicine 2016, 176: 318. PMID: 26857025, DOI: 10.1001/jamainternmed.2015.7993.
Multimorbidity in Older Adults with Heart FailureDharmarajan K, Dunlay SM. Multimorbidity in Older Adults with Heart Failure Clinics In Geriatric Medicine 2016, 32: 277-289. PMID: 27113146, DOI: 10.1016/j.cger.2016.01.002.
Comprehensive Strategies to Reduce Readmissions in Older Patients With Cardiovascular DiseaseDharmarajan K. Comprehensive Strategies to Reduce Readmissions in Older Patients With Cardiovascular Disease Canadian Journal Of Cardiology 2016, 32: 1306-1314. PMID: 27084075, DOI: 10.1016/j.cjca.2016.01.030.
Opportunities and Challenges for Reducing Hospital Revisits.Dharmarajan K, Krumholz HM. Opportunities and Challenges for Reducing Hospital Revisits. Annals Of Internal Medicine 2015, 163: 727-8. PMID: 26524581, DOI: 10.7326/l15-5154-2.
Hospital variation in admission to intensive care units for patients with acute myocardial infarctionChen R, Strait KM, Dharmarajan K, Li SX, Ranasinghe I, Martin J, Fazel R, Masoudi FA, Cooke CR, Nallamothu BK, Krumholz HM. Hospital variation in admission to intensive care units for patients with acute myocardial infarction American Heart Journal 2015, 170: 1161-1169. PMID: 26678638, PMCID: PMC5459386, DOI: 10.1016/j.ahj.2015.09.003.
Variation in care and outcome following myocardial infarctionDharmarajan K. Variation in care and outcome following myocardial infarction The BMJ 2015, 351: h4133. PMID: 26254446, DOI: 10.1136/bmj.h4133.
National Trends in Hospital Readmission Rates among Medicare Fee-for-Service Survivors of Mitral Valve Surgery, 1999–2010Dodson JA, Wang Y, Murugiah K, Dharmarajan K, Cooper Z, Hashim S, Nuti SV, Spatz E, Desai N, Krumholz HM. National Trends in Hospital Readmission Rates among Medicare Fee-for-Service Survivors of Mitral Valve Surgery, 1999–2010 PLOS ONE 2015, 10: e0132470. PMID: 26147225, PMCID: PMC4493110, DOI: 10.1371/journal.pone.0132470.
Sex Differences in the Rate, Timing, and Principal Diagnoses of 30-Day Readmissions in Younger Patients with Acute Myocardial InfarctionDreyer RP, Ranasinghe I, Wang Y, Dharmarajan K, Murugiah K, Nuti SV, Hsieh AF, Spertus JA, Krumholz HM. Sex Differences in the Rate, Timing, and Principal Diagnoses of 30-Day Readmissions in Younger Patients with Acute Myocardial Infarction Circulation 2015, 132: 158-166. PMID: 26085455, PMCID: PMC5322973, DOI: 10.1161/circulationaha.114.014776.
Hospital Variability in Use of Anticoagulant Strategies During Acute Myocardial Infarction Treated With an Early Invasive StrategyArnold SV, Li SX, Alexander KP, Spertus JA, Nallamothu BK, Curtis JP, Kosiborod M, Gupta A, Wang TY, Lin H, Dharmarajan K, Strait KM, Lowe TJ, Krumholz HM. Hospital Variability in Use of Anticoagulant Strategies During Acute Myocardial Infarction Treated With an Early Invasive Strategy Journal Of The American Heart Association 2015, 4: e002009. PMID: 26077589, PMCID: PMC4599539, DOI: 10.1161/jaha.115.002009.
Opportunities and challenges for reducing hospital revisits.Dharmarajan K, Krumholz HM. Opportunities and challenges for reducing hospital revisits. Annals Of Internal Medicine 2015, 162: 793-4. PMID: 26030636, DOI: 10.7326/m15-0878.
Balloon animals, guitars, and fewer blood draws: applying strategies from pediatrics to the treatment of hospitalized adults.O'Brien MR, Rosenthal MS, Dharmarajan K, Krumholz HM. Balloon animals, guitars, and fewer blood draws: applying strategies from pediatrics to the treatment of hospitalized adults. Annals Of Internal Medicine 2015, 162: 726-7. PMID: 25984849, DOI: 10.7326/m14-2219.
Patients need safer hospitals, every day of the weekDharmarajan K, Kim N, Krumholz HM. Patients need safer hospitals, every day of the week The BMJ 2015, 350: h1826. PMID: 25877669, DOI: 10.1136/bmj.h1826.
Readmissions After Carotid Artery Revascularization in the Medicare PopulationAl-Damluji MS, Dharmarajan K, Zhang W, Geary LL, Stilp E, Dardik A, Mena-Hurtado C, Curtis JP. Readmissions After Carotid Artery Revascularization in the Medicare Population Journal Of The American College Of Cardiology 2015, 65: 1398-1408. PMID: 25857904, PMCID: PMC4403264, DOI: 10.1016/j.jacc.2015.01.048.
Trajectories of risk after hospitalization for heart failure, acute myocardial infarction, or pneumonia: retrospective cohort studyDharmarajan K, Hsieh AF, Kulkarni VT, Lin Z, Ross JS, Horwitz LI, Kim N, Suter LG, Lin H, Normand SL, Krumholz HM. Trajectories of risk after hospitalization for heart failure, acute myocardial infarction, or pneumonia: retrospective cohort study The BMJ 2015, 350: h411. PMID: 25656852, PMCID: PMC4353309, DOI: 10.1136/bmj.h411.
Intravenous Fluids in Acute Decompensated Heart FailureBikdeli B, Strait KM, Dharmarajan K, Li SX, Mody P, Partovian C, Coca SG, Kim N, Horwitz LI, Testani JM, Krumholz HM. Intravenous Fluids in Acute Decompensated Heart Failure JACC Heart Failure 2015, 3: 127-133. PMID: 25660836, PMCID: PMC4438991, DOI: 10.1016/j.jchf.2014.09.007.
Risk after hospitalization: We have a lot to learnDharmarajan K, Krumholz HM. Risk after hospitalization: We have a lot to learn Journal Of Hospital Medicine 2015, 10: 135-136. PMID: 25627350, PMCID: PMC4337805, DOI: 10.1002/jhm.2309.
Trends in Hospitalizations Among Medicare Survivors of Aortic Valve Replacement in the United States From 1999 to 2010Murugiah K, Wang Y, Dodson JA, Nuti SV, Dharmarajan K, Ranasinghe I, Cooper Z, Krumholz HM. Trends in Hospitalizations Among Medicare Survivors of Aortic Valve Replacement in the United States From 1999 to 2010 The Annals Of Thoracic Surgery 2014, 99: 509-517. PMID: 25527425, PMCID: PMC4454375, DOI: 10.1016/j.athoracsur.2014.08.045.
Readmissions after Hospitalization for Heart Failure, Acute Myocardial Infarction, or Pneumonia among Young and Middle-Aged Adults: A Retrospective Observational Cohort StudyRanasinghe I, Wang Y, Dharmarajan K, Hsieh AF, Bernheim SM, Krumholz HM. Readmissions after Hospitalization for Heart Failure, Acute Myocardial Infarction, or Pneumonia among Young and Middle-Aged Adults: A Retrospective Observational Cohort Study PLOS Medicine 2014, 11: e1001737. PMID: 25268126, PMCID: PMC4181962, DOI: 10.1371/journal.pmed.1001737.
Strategies to Reduce 30-Day Readmissions in Older Patients Hospitalized with Heart Failure and Acute Myocardial InfarctionDharmarajan K, Krumholz HM. Strategies to Reduce 30-Day Readmissions in Older Patients Hospitalized with Heart Failure and Acute Myocardial Infarction Current Geriatrics Reports 2014, 3: 306-315. PMID: 25431752, PMCID: PMC4242430, DOI: 10.1007/s13670-014-0103-8.
National Trends in Recurrent AMI Hospitalizations 1 Year After Acute Myocardial Infarction in Medicare Beneficiaries: 1999–2010Chaudhry SI, Khan RF, Chen J, Dharmarajan K, Dodson JA, Masoudi FA, Wang Y, Krumholz HM. National Trends in Recurrent AMI Hospitalizations 1 Year After Acute Myocardial Infarction in Medicare Beneficiaries: 1999–2010 Journal Of The American Heart Association 2014, 3: e001197. PMID: 25249298, PMCID: PMC4323804, DOI: 10.1161/jaha.114.001197.
Use of Intravenous Diuretics on Day of Discharge in Adults Hospitalized for Heart FailureFazel R, Strait KM, Bikdeli B, Dharmarajan K, Krumholz HM. Use of Intravenous Diuretics on Day of Discharge in Adults Hospitalized for Heart Failure Journal Of Cardiac Failure 2014, 20: 706-707. PMID: 24951932, PMCID: PMC4427892, DOI: 10.1016/j.cardfail.2014.06.354.
National trends in stroke after acute myocardial infarction among Medicare patients in the United States: 1999 to 2010Wang Y, Lichtman JH, Dharmarajan K, Masoudi FA, Ross JS, Dodson JA, Chen J, Spertus JA, Chaudhry SI, Nallamothu BK, Krumholz HM. National trends in stroke after acute myocardial infarction among Medicare patients in the United States: 1999 to 2010 American Heart Journal 2014, 169: 78-85.e4. PMID: 25497251, PMCID: PMC4824179, DOI: 10.1016/j.ahj.2014.06.011.
Hospital Variation in the Use of Noninvasive Cardiac Imaging and Its Association With Downstream Testing, Interventions, and OutcomesSafavi KC, Li SX, Dharmarajan K, Venkatesh AK, Strait KM, Lin H, Lowe TJ, Fazel R, Nallamothu BK, Krumholz HM. Hospital Variation in the Use of Noninvasive Cardiac Imaging and Its Association With Downstream Testing, Interventions, and Outcomes JAMA Internal Medicine 2014, 174: 546-553. PMID: 24515551, PMCID: PMC5459406, DOI: 10.1001/jamainternmed.2013.14407.
Hospital Variation in Noninvasive Positive Pressure Ventilation for Acute Decompensated Heart FailureKulkarni VT, Kim N, Dai Y, Dharmarajan K, Safavi KC, Bikdeli B, Lindenauer PK, Testani J, Dries DL, Krumholz HM. Hospital Variation in Noninvasive Positive Pressure Ventilation for Acute Decompensated Heart Failure Circulation Heart Failure 2014, 7: 427-433. PMID: 24633829, PMCID: PMC4386575, DOI: 10.1161/circheartfailure.113.000698.
Most Important Outcomes Research Papers on Cardiac Arrest and Cardiopulmonary ResuscitationMurugiah K, Chen SI, Dharmarajan K, Nuti SV, Wayda B, Shojaee A, Ranasinghe I, Dreyer RP. Most Important Outcomes Research Papers on Cardiac Arrest and Cardiopulmonary Resuscitation Circulation Cardiovascular Quality And Outcomes 2014, 7: 335-345. PMID: 24619323, DOI: 10.1161/circoutcomes.114.000957.
Protocol for the China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) retrospective study of coronary catheterisation and percutaneous coronary interventionLi J, Dharmarajan K, Li X, Lin Z, Normand SL, Krumholz HM, Jiang L, . Protocol for the China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) retrospective study of coronary catheterisation and percutaneous coronary intervention BMJ Open 2014, 4: e004595. PMID: 24607563, PMCID: PMC3948460, DOI: 10.1136/bmjopen-2013-004595.
Caution Warranted When Defining Contraindications in Initiating β-Blocker Therapy—ReplyDharmarajan K, Krumholz HM. Caution Warranted When Defining Contraindications in Initiating β-Blocker Therapy—Reply JAMA Internal Medicine 2014, 174: 481-482. PMID: 24590098, DOI: 10.1001/jamainternmed.2013.13685.
Most Important Outcomes Research Papers on Stroke and Transient Ischemic AttackDreyer R, Murugiah K, Nuti SV, Dharmarajan K, Chen SI, Chen R, Wayda B, Ranasinghe I. Most Important Outcomes Research Papers on Stroke and Transient Ischemic Attack Circulation Cardiovascular Quality And Outcomes 2014, 7: 191-204. PMID: 24425708, DOI: 10.1161/circoutcomes.113.000831.
Hospital readmission performance and patterns of readmission: retrospective cohort study of Medicare admissionsDharmarajan K, Hsieh AF, Lin Z, Bueno H, Ross JS, Horwitz LI, Barreto-Filho JA, Kim N, Suter LG, Bernheim SM, Drye EE, Krumholz HM. Hospital readmission performance and patterns of readmission: retrospective cohort study of Medicare admissions The BMJ 2013, 347: f6571. PMID: 24259033, PMCID: PMC3898430, DOI: 10.1136/bmj.f6571.
The China Patient-Centered Evaluative Assessment of Cardiac Events (China PEACE) Retrospective Study of Acute Myocardial InfarctionDharmarajan K, Li J, Li X, Lin Z, Krumholz HM, Jiang L. The China Patient-Centered Evaluative Assessment of Cardiac Events (China PEACE) Retrospective Study of Acute Myocardial Infarction Circulation Cardiovascular Quality And Outcomes 2013, 6: 732-740. PMID: 24221838, PMCID: PMC4054693, DOI: 10.1161/circoutcomes.113.000441.
National Trends in Heart Failure Hospitalization After Acute Myocardial Infarction for Medicare BeneficiariesChen J, Hsieh AF, Dharmarajan K, Masoudi FA, Krumholz HM. National Trends in Heart Failure Hospitalization After Acute Myocardial Infarction for Medicare Beneficiaries Circulation 2013, 128: 2577-2584. PMID: 24190958, PMCID: PMC4415510, DOI: 10.1161/circulationaha.113.003668.
Acute Decompensated Heart Failure Is Routinely Treated as a Cardiopulmonary SyndromeDharmarajan K, Strait KM, Lagu T, Lindenauer PK, Tinetti ME, Lynn J, Li SX, Krumholz HM. Acute Decompensated Heart Failure Is Routinely Treated as a Cardiopulmonary Syndrome PLOS ONE 2013, 8: e78222. PMID: 24250751, PMCID: PMC3824040, DOI: 10.1371/journal.pone.0078222.
Contraindicated Initiation of β-Blocker Therapy in Patients Hospitalized for Heart FailureDharmarajan K, Masoudi FA, Spertus JA, Li SX, Krumholz HM. Contraindicated Initiation of β-Blocker Therapy in Patients Hospitalized for Heart Failure JAMA Internal Medicine 2013, 173: 1547-1549. PMID: 23797379, PMCID: PMC4043342, DOI: 10.1001/jamainternmed.2013.7717.
Most Important Outcomes Research Papers on HypertensionChen R, Dharmarajan K, Kulkarni VT, Punnanithinont N, Gupta A, Bikdeli B, Mody PS, Ranasinghe I. Most Important Outcomes Research Papers on Hypertension Circulation Cardiovascular Quality And Outcomes 2013, 6: e26-e35. PMID: 23838106, PMCID: PMC8152105, DOI: 10.1161/circoutcomes.113.000424.
Spending more, doing more, or both? An alternative method for quantifying utilization during hospitalizationsLagu T, Krumholz HM, Dharmarajan K, Partovian C, Kim N, Mody PS, Li S, Strait KM, Lindenauer PK. Spending more, doing more, or both? An alternative method for quantifying utilization during hospitalizations Journal Of Hospital Medicine 2013, 8: 373-379. PMID: 23757115, PMCID: PMC4014449, DOI: 10.1002/jhm.2046.
Most Important Outcomes Research Papers on Treatment of Stable Coronary Artery DiseaseBikdeli B, Ranasinghe I, Chen R, Gupta A, Lampropulos JF, Kulkarni VT, Mody PS, Dharmarajan K. Most Important Outcomes Research Papers on Treatment of Stable Coronary Artery Disease Circulation Cardiovascular Quality And Outcomes 2013, 6: e17-e25. PMID: 23674308, DOI: 10.1161/circoutcomes.113.000310.
Dominance of Furosemide for Loop Diuretic Therapy in Heart Failure Time to Revisit the Alternatives?Bikdeli B, Strait KM, Dharmarajan K, Partovian C, Coca SG, Kim N, Li SX, Testani JM, Khan U, Krumholz HM. Dominance of Furosemide for Loop Diuretic Therapy in Heart Failure Time to Revisit the Alternatives? Journal Of The American College Of Cardiology 2013, 61: 1549-1550. PMID: 23500272, PMCID: PMC4038646, DOI: 10.1016/j.jacc.2012.12.043.
Most Important Outcomes Research Papers on Variation in Cardiovascular DiseaseLampropulos JF, Gupta A, Kulkarni VT, Mody P, Chen R, Bikdeli B, Dharmarajan K. Most Important Outcomes Research Papers on Variation in Cardiovascular Disease Circulation Cardiovascular Quality And Outcomes 2013, 6: e9-e16. PMID: 23481532, DOI: 10.1161/circoutcomes.113.000185.
National Trends in Heart Failure Hospital Stay Rates, 2001 to 2009Chen J, Dharmarajan K, Wang Y, Krumholz HM. National Trends in Heart Failure Hospital Stay Rates, 2001 to 2009 Journal Of The American College Of Cardiology 2013, 61: 1078-1088. PMID: 23473413, PMCID: PMC3939721, DOI: 10.1016/j.jacc.2012.11.057.
Variation Exists in Rates of Admission to Intensive Care Units for Heart Failure Patients Across Hospitals in the United StatesSafavi KC, Dharmarajan K, Kim N, Strait KM, Li SX, Chen SI, Lagu T, Krumholz HM. Variation Exists in Rates of Admission to Intensive Care Units for Heart Failure Patients Across Hospitals in the United States Circulation 2013, 127: 923-929. PMID: 23355624, PMCID: PMC3688061, DOI: 10.1161/circulationaha.112.001088.
Diagnoses and Timing of 30-Day Readmissions After Hospitalization for Heart Failure, Acute Myocardial Infarction, or PneumoniaDharmarajan K, Hsieh AF, Lin Z, Bueno H, Ross JS, Horwitz LI, Barreto-Filho JA, Kim N, Bernheim SM, Suter LG, Drye EE, Krumholz HM. Diagnoses and Timing of 30-Day Readmissions After Hospitalization for Heart Failure, Acute Myocardial Infarction, or Pneumonia JAMA 2013, 309: 355-363. PMID: 23340637, PMCID: PMC3688083, DOI: 10.1001/jama.2012.216476.
Most Important Outcomes Research Papers on Cardiovascular Disease in WomenGupta A, Lampropulos JF, Bikdeli B, Mody P, Chen R, Kulkarni VT, Dharmarajan K. Most Important Outcomes Research Papers on Cardiovascular Disease in Women Circulation Cardiovascular Quality And Outcomes 2013, 6: e1-e7. PMID: 23322810, DOI: 10.1161/circoutcomes.112.970202.
Most Important Outcomes Research Papers on Valvular Heart DiseaseLampropulos JF, Bikdeli B, Gupta A, Mody P, Kulkarni VT, Chen R, Dharmarajan K. Most Important Outcomes Research Papers on Valvular Heart Disease Circulation Cardiovascular Quality And Outcomes 2012, 5: e95-e103. PMID: 23170009, DOI: 10.1161/circoutcomes.112.969766.
Most Important Outcomes Research Papers on Anticoagulation for Cardiovascular DiseaseBikdeli B, Gupta A, Mody P, Lampropulos JF, Dharmarajan K. Most Important Outcomes Research Papers on Anticoagulation for Cardiovascular Disease Circulation Cardiovascular Quality And Outcomes 2012, 5: e65-e74. PMID: 22991352, DOI: 10.1161/circoutcomes.112.968701.
Most Important Articles on Cardiovascular Disease Among Racial and Ethnic MinoritiesMody P, Gupta A, Bikdeli B, Lampropulos JF, Dharmarajan K. Most Important Articles on Cardiovascular Disease Among Racial and Ethnic Minorities Circulation Cardiovascular Quality And Outcomes 2012, 5: e33-e41. PMID: 22811508, DOI: 10.1161/circoutcomes.112.967638.
Procedure Intensity and the Cost of CareChen SI, Dharmarajan K, Kim N, Strait KM, Li SX, Safavi KC, Lindenauer PK, Krumholz HM, Lagu T. Procedure Intensity and the Cost of Care Circulation Cardiovascular Quality And Outcomes 2012, 5: 308-313. PMID: 22576844, PMCID: PMC3415230, DOI: 10.1161/circoutcomes.112.966069.
Most Important Outcomes Research Papers in Cardiovascular Disease in the ElderlyGupta A, Mody P, Bikdeli B, Lampropulos JF, Dharmarajan K. Most Important Outcomes Research Papers in Cardiovascular Disease in the Elderly Circulation Cardiovascular Quality And Outcomes 2012, 5: e17-e26. PMID: 22592757, DOI: 10.1161/circoutcomes.112.966531.
Most Important Papers in Health Costs, Cost-Effectiveness, and Resource UtilizationDharmarajan K, Lampropulos J, Bikdeli B, Mody P, Gupta A. Most Important Papers in Health Costs, Cost-Effectiveness, and Resource Utilization Circulation Cardiovascular Quality And Outcomes 2012, 5: e9-e15. PMID: 22438466, DOI: 10.1161/circoutcomes.112.965830.
Transthyretin Cardiac Amyloidoses in Older North AmericansDharmarajan K, Maurer MS. Transthyretin Cardiac Amyloidoses in Older North Americans Journal Of The American Geriatrics Society 2012, 60: 765-774. PMID: 22329529, PMCID: PMC3325376, DOI: 10.1111/j.1532-5415.2011.03868.x.

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Kumar Dharmarajan, MD, MBA

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